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2021

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A Comparative Study Of Saudi Arabian And U.S. Pre-Service Teachers’ Readiness For Technology Integration, Yosra M. Bugis, Randy Larkins Feb 2021

A Comparative Study Of Saudi Arabian And U.S. Pre-Service Teachers’ Readiness For Technology Integration, Yosra M. Bugis, Randy Larkins

Journal of Educational Research and Innovation

The purpose of this study is to understand how prepared teachers in two countries are to utilize technology effectively in a physical and virtual classroom environment. This research is a comparative study of Saudi Arabian and US preservice teachers’ readiness for technology integration in their actual teaching practices. Survey methodology was used to measure both knowledge and attitudinal variables found to be important to later integration of technology into teaching among preservice teachers. The results provide updated insight into the status of US and Saudi Arabian preservice teachers’ proficiencies and attitudes toward integrating technology into their teaching and implications for …

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Gated Practice: A Study Of Liberalism, Religion, And The Academy, Adelaide R. Gaughran-Bedell Feb 2021

Gated Practice: A Study Of Liberalism, Religion, And The Academy, Adelaide R. Gaughran-Bedell

Tapestries: Interwoven voices of local and global identities

This paper is an exploration of liberalism within the United States. More specifically, it looks at the ways in which liberalism is kept within academia and the ways it acts to construct and neutralize whiteness. Taking cues from Aisha M. Beliso-De Jesús in her essay Confounded Identities: A Meditation on Race, Feminism, and Religious Studies in Times of White Supremacy, this paper uses a religious studies methodology to deconstruct the structures and effects of liberalism. By framing liberalism as a religion and analysing it through this lens, Gaughran-Bedell seeks to deconstruct the secular bias that often applies to liberalism. If …

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How We Care Matters: Reproductive Justice And The Black Maternal Health Crisis, Addisa Z. Rigaud Feb 2021

How We Care Matters: Reproductive Justice And The Black Maternal Health Crisis, Addisa Z. Rigaud

Tapestries: Interwoven voices of local and global identities

Using a framework of Reproductive Justice, this piece locates what reproductive care could be and should be. In doing so, I highlight the inherent potential of Midwifery practices to remedy the Black Maternal and Infant Mortality Crisis in the United States.

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A Bisphosphonate With A Low Hydroxyapatite Binding Affinity Prevents Bone Loss In Mice After Ovariectomy And Reverses Rapidly With Treatment Cessation, Abigail A. Coffman, Jelena Basta-Pljakic, Rosa M. Guerra, Frank H. Ebetino, Mark W. Lundy, Robert J. Majeska, Mitchell B. Schaffler Feb 2021

A Bisphosphonate With A Low Hydroxyapatite Binding Affinity Prevents Bone Loss In Mice After Ovariectomy And Reverses Rapidly With Treatment Cessation, Abigail A. Coffman, Jelena Basta-Pljakic, Rosa M. Guerra, Frank H. Ebetino, Mark W. Lundy, Robert J. Majeska, Mitchell B. Schaffler

Publications and Research

Bisphosphonates (BPs) are a mainstay of osteoporosis treatment; however, concerns about bone health based on oversuppression of remodeling remain. Long-term bone remodeling suppression adversely affects bone material properties with microdamage accumulation and reduced fracture toughness in animals and increases in matrix mineralization and atypical femur fractures in patients. Although a “drug holiday” from BPs to restore remodeling and improve bone quality seems reasonable, clinical BPs have long functional half-lives because of their high hydroxyapatite (HAP) binding affinities. This places a practical limit on the reversibility and effectiveness of a drug holiday. BPs with low HAP affinity and strong osteoclast inhibition …

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Characterization Of Two Zygnema Strains (Zygnema Circumcarinatum Sag 698-1a And Sag 698-1b) And A Rapid Method To Estimate Nuclear Genome Size Of Zygnematophycean Green Algae, Xuehuan Feng, Andreas Holzinger, Charlotte Permann, Dirk Anderson, Yanbin Yin Feb 2021

Characterization Of Two Zygnema Strains (Zygnema Circumcarinatum Sag 698-1a And Sag 698-1b) And A Rapid Method To Estimate Nuclear Genome Size Of Zygnematophycean Green Algae, Xuehuan Feng, Andreas Holzinger, Charlotte Permann, Dirk Anderson, Yanbin Yin

Food for Health: Publications

Zygnematophyceae green algae (ZGA) have been shown to be the closest relatives of land plants. Three nuclear genomes (Spirogloea muscicola, Mesotaenium endlicherianum, and Penium margaritaceum) of ZGA have been recently published, and more genomes are underway. Here we analyzed two Zygnema circumcarinatum strains SAG 698-1a (mating +) and SAG 698-1b (mating −) and found distinct cell sizes and other morphological differences. The molecular identities of the two strains were further investigated by sequencing their 18S rRNA, psaA and rbcL genes. These marker genes of SAG 698-1a were surprisingly much more similar to Z. cylindricum (SAG 698-2) than to SAG 698-1b. …

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Characterization Of Two Zygnema Strains (Zygnema Circumcarinatum Sag 698-1a And Sag 698-1b) And A Rapid Method To Estimate Nuclear Genome Size Of Zygnematophycean Green Algae, Xuehuan Feng, Andreas Holzinger, Charlotte Permann, Dirk Anderson, Yanbin Yin Feb 2021

Characterization Of Two Zygnema Strains (Zygnema Circumcarinatum Sag 698-1a And Sag 698-1b) And A Rapid Method To Estimate Nuclear Genome Size Of Zygnematophycean Green Algae, Xuehuan Feng, Andreas Holzinger, Charlotte Permann, Dirk Anderson, Yanbin Yin

Food for Health: Publications

Zygnematophyceae green algae (ZGA) have been shown to be the closest relatives of land plants. Three nuclear genomes (Spirogloea muscicola, Mesotaenium endlicherianum, and Penium margaritaceum) of ZGA have been recently published, and more genomes are underway. Here we analyzed two Zygnema circumcarinatum strains SAG 698-1a (mating +) and SAG 698-1b (mating −) and found distinct cell sizes and other morphological differences. The molecular identities of the two strains were further investigated by sequencing their 18S rRNA, psaA and rbcL genes. These marker genes of SAG 698-1a were surprisingly much more similar to Z. cylindricum (SAG 698-2) than to SAG 698-1b. …

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Characterization Of Two Zygnema Strains (Zygnema Circumcarinatum Sag 698-1a And Sag 698-1b) And A Rapid Method To Estimate Nuclear Genome Size Of Zygnematophycean Green Algae, Xuehuan Feng, Andreas Holzinger, Charlotte Permann, Dirk Anderson, Yanbin Yin Feb 2021

Characterization Of Two Zygnema Strains (Zygnema Circumcarinatum Sag 698-1a And Sag 698-1b) And A Rapid Method To Estimate Nuclear Genome Size Of Zygnematophycean Green Algae, Xuehuan Feng, Andreas Holzinger, Charlotte Permann, Dirk Anderson, Yanbin Yin

Food for Health: Publications

Zygnematophyceae green algae (ZGA) have been shown to be the closest relatives of land plants. Three nuclear genomes (Spirogloea muscicola, Mesotaenium endlicherianum, and Penium margaritaceum) of ZGA have been recently published, and more genomes are underway. Here we analyzed two Zygnema circumcarinatum strains SAG 698-1a (mating +) and SAG 698-1b (mating −) and found distinct cell sizes and other morphological differences. The molecular identities of the two strains were further investigated by sequencing their 18S rRNA, psaA and rbcL genes. These marker genes of SAG 698-1a were surprisingly much more similar to Z. cylindricum (SAG 698-2) than to SAG 698-1b. …

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The Bg News February 10, 2021, Bowling Green State University Feb 2021

The Bg News February 10, 2021, Bowling Green State University

BG News (Student Newspaper)

The BGSU campus student newspaper. February 10, 2021. Volume 100-Issue 20.

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Evolution Of Realized Eltonian Niches Across Rajidae Species, Oliver N. Shipley, Joseph B. Kelly, Joseph J. Bizzarro, Jill A. Olin, Robert M. Cerrato, Michael Power, Michael G. Frisk Feb 2021

Evolution Of Realized Eltonian Niches Across Rajidae Species, Oliver N. Shipley, Joseph B. Kelly, Joseph J. Bizzarro, Jill A. Olin, Robert M. Cerrato, Michael Power, Michael G. Frisk

Michigan Tech Publications, Part 1

The notion that closely related species resemble each other in ecological niche space (i.e., phylogenetic dependence) has been a long-standing, contentious paradigm in evolutionary biology, the incidence of which is important for predicting the ecosystem-level effects of species loss. Despite being examined across a multitude of terrestrial taxa, many aspects of niche conservatism have yet to be explored in marine species, especially for characteristics related to resource use and trophic behavior (Eltonian niche characteristics, ENCs). We combined ENCs derived from stable isotope ratios at assemblage- and species-levels with phylogenetic comparative methods, to test the hypotheses that benthic marine fishes (1) …

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Understanding Molecular Interaction Between Sulfadoxine And Human Serum Albumin Through Spectroscopic And Molecular Docking Methods, Jaslene Anne Francis Feb 2021

Understanding Molecular Interaction Between Sulfadoxine And Human Serum Albumin Through Spectroscopic And Molecular Docking Methods, Jaslene Anne Francis

Student Works (2020-2029)

The main aim of this study was to characterize the molecular interaction between sulfadoxine (SDN) and the major transport protein in the blood plasma, human serum albumin (HSA) using fluorescence, absorption, circular dichroism and voltammetric techniques along with computational methods. SDN-induced changes in the fluorescence intensity of HSA hinted the complex formation between SDN and HSA. Both values of the bimolecular quenching rate constant and UV-Vis absorption spectral results characterized the quenching of HSA fluorescence as static quenching. Analysis of the quenching results showed a moderate binding affinity (Ka = 3.39×104 M‒1 at 300 K) between SDN and HSA. Thermodynamic …

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Potential Control Of The Seed Bug Elasmolomus Pallens By Entomopathogenic Fungi And Assessment Of Its Risks For The Transmission Of Aflatoxins, Fidelis Umaru Fredrick Feb 2021

Potential Control Of The Seed Bug Elasmolomus Pallens By Entomopathogenic Fungi And Assessment Of Its Risks For The Transmission Of Aflatoxins, Fidelis Umaru Fredrick

Student Works (2020-2029)

Elasmolomus pallens is a post-harvest insect pest which causes yield loss of peanuts and sesame in Africa and Asia. In view of mitigating the use of synthetic insecticides on the environment, this study evaluated the potential of entomopathogenic fungi for the biological control of E. pallens and assessment of the bug rostrum for its risks of aflatoxins transmission. Adults bugs were dipped briefly in different conidial concentrations of the isolates and observed at 25 ± 2 ℃, 80 ± 10 RH and 14: 10 L: D for 10 days. Dose-response bioassay employed dipping and filter paper methods for both 0.05% …

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Noise Distracts Foraging Bats, Louise C. Allen, Nickolay I. Hristov, Juliette J. Rubin, Joseph T. Lightsey, Jesse R. Barber Feb 2021

Noise Distracts Foraging Bats, Louise C. Allen, Nickolay I. Hristov, Juliette J. Rubin, Joseph T. Lightsey, Jesse R. Barber

Biology Faculty Publications and Presentations

Predators frequently must detect and localize their prey in challenging environments. Noisy environments have been prevalent across the evolutionary history of predator–prey relationships, but now with increasing anthropogenic activities noise is becoming a more prominent feature of many landscapes. Here, we use the gleaning pallid bat, Antrozous pallidus, to investigate the mechanism by which noise disrupts hunting behaviour. Noise can primarily function to mask—obscure by spectrally overlapping a cue of interest, or distract—occupy an animal's attentional or other cognitive resources. Using band-limited white noise treatments that either overlapped the frequencies of a prey cue or did not …

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Climate-Mediated Changes To Linked Terrestrial And Marine Ecosystems Across The Northeast Pacific Coastal Temperate Rainforest Margin, Allison Lynn Bidlack, Sarah Bisbing, Brian Buma, Heida L. Diefenderfer, Jason B. Fellman, William C. Floyd, Ian Giesbrecht, Amritpal Lally, Ken P. Lertzman, Steven S. Perakis, David E. Butman, David V. D'Amore, Sean W. Fleming, Eran Hood, Brian P. Hunt, Peter M. Kiffney, Gavin Mcnicol, Brian Menounos, Suzanne Tank Feb 2021

Climate-Mediated Changes To Linked Terrestrial And Marine Ecosystems Across The Northeast Pacific Coastal Temperate Rainforest Margin, Allison Lynn Bidlack, Sarah Bisbing, Brian Buma, Heida L. Diefenderfer, Jason B. Fellman, William C. Floyd, Ian Giesbrecht, Amritpal Lally, Ken P. Lertzman, Steven S. Perakis, David E. Butman, David V. D'Amore, Sean W. Fleming, Eran Hood, Brian P. Hunt, Peter M. Kiffney, Gavin Mcnicol, Brian Menounos, Suzanne Tank

Alaska Coastal Rainforest Center

Coastal margins are important areas of materials flux that link terrestrial and marine ecosystems. Consequently, climate-mediated changes to coastal terrestrial ecosystems and hydrologic regimes have high potential to influence nearshore ocean chemistry and food web dynamics. Research from tightly coupled, high-flux coastal ecosystems can advance understanding of terrestrial–marine links and climate sensitivities more generally. In the present article, we use the northeast Pacific coastal temperate rainforest as a model system to evaluate such links. We focus on key above- and belowground production and hydrological transport processes that control the land-to-ocean flow of materials and their influence on nearshore marine ecosystems. …

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Dewetting Induced Lipid Bilayer Multicomponent Scaffold For Synthetic Cell Vesicle And Their Stability, Anjana Khanal Feb 2021

Dewetting Induced Lipid Bilayer Multicomponent Scaffold For Synthetic Cell Vesicle And Their Stability, Anjana Khanal

Theses and Dissertations

This thesis introduces a microfluidic method to generate monodisperse water-in-oil-in water double emulsions. The microfluidic method is able to produce double emulsions with high degree of controllability and flexibility on size and number of droplets. We demonstrate this by producing double emulsions containing 1-8 inner water droplets and studied their dewetting phenomena to lipid bilayer scaffold. Our study shows that for the dewetting phenomenon to occur the oil must be volatile, polar and should make low contact angle with the involved interfaces. The chloroform shows self-emulsification behavior in presence of surfactant F127. The topological droplets formation with multiple compartments is …

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Establishing A Mechanistic Link Between Disturbed Flow And Aneurysm Formation In A 3d Cerebral Bifurcation Model, Nesrine Bouhrira Feb 2021

Establishing A Mechanistic Link Between Disturbed Flow And Aneurysm Formation In A 3d Cerebral Bifurcation Model, Nesrine Bouhrira

Theses and Dissertations

The effect of disturbed flow profiles on the endothelium have been studied extensively in systemic vasculature, but less is known about the response of the blood-brain barrier (BBB) to these flow regimes. Here we investigate the effect of steady and pulsatile disturbed flow on the integrity of the BBB using a three-dimensional, perfusable bifurcation model consisting of a co-culture of endothelial cells with mural and glial cells. Experimental flow patterns predicted by computational fluid dynamics mimic in vivo flow regimes, specifically the presence of a recirculation zone immediately downstream of the bifurcation reveal periodic changes in the instantaneous shear stress …

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The Effect Of A Text-Message Based Hydration Education Intervention On Hydration Knowledge And Behavior Of Division I Female Collegiate Soccer Players, Milaena Ferrarese Feb 2021

The Effect Of A Text-Message Based Hydration Education Intervention On Hydration Knowledge And Behavior Of Division I Female Collegiate Soccer Players, Milaena Ferrarese

Theses and Dissertations

There is increasing evidence of athletes entering their training sessions in an already dehydrated state. It is crucial for athletes to properly replenish fluid and electrolytes lost via sweat in order to optimize their training and recovery. The purpose of this study is to assess the effect of a text-message based hydration education intervention on the knowledge and hydration status of division I female collegiate soccer players.A total of 14 participants completed baseline testing, which included hydration knowledge and behavior questionnaires, and pre- and post-practice weights to calculate % weight change (%WC). The participants also provided a baseline urine sample …

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The Parthenon, February 10, 2021, Brittany Hively, Grant Goodrich, Emma Berry, Xena Bunton, Isabella Robinson, Tyler Spence, Denise Jackson, Zachary Hiser Feb 2021

The Parthenon, February 10, 2021, Brittany Hively, Grant Goodrich, Emma Berry, Xena Bunton, Isabella Robinson, Tyler Spence, Denise Jackson, Zachary Hiser

The Parthenon

No abstract provided.

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Hippocampus Guides Adaptive Learning During Dynamic Social Interactions, Oriel Feldmanhall, David F. Montez, Elizabeth A. Phelps, Lila Davachi, Vishnu P. Murty Feb 2021

Hippocampus Guides Adaptive Learning During Dynamic Social Interactions, Oriel Feldmanhall, David F. Montez, Elizabeth A. Phelps, Lila Davachi, Vishnu P. Murty

Open Access Publications

How do we evaluate whether someone will make a good friend or collaborative peer? A hallmark of human cognition is the ability to make adaptive decisions based on information garnered from limited prior experiences. Using an interactive social task measuring adaptive choice (deciding who to reengage or avoid) in male and female participants, we find the hippocampus supports value-based social choices following single-shot learning. These adaptive choices elicited a suppression signal in the hippocampus, revealing sensitivity for the subjective perception of a person and how well they treat you during choice. The extent to which the hippocampus was suppressed was …

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Antagonistic Cytoprotective Effects Of C60 Fullerene Nanoparticles In Simultaneous Exposure To Benzo[A]Pyrene In A Molluscan Animal Model, Awadhesh N. Jha Feb 2021

Antagonistic Cytoprotective Effects Of C60 Fullerene Nanoparticles In Simultaneous Exposure To Benzo[A]Pyrene In A Molluscan Animal Model, Awadhesh N. Jha

School of Biological and Marine Sciences

The hypothesis that C60 fullerene nanoparticles (C60) exert an antagonistic interactive effect on the toxicity of benzo[a]pyrene (BaP) has been supported by this investigation. Mussels were exposed to BaP (5, 50 & 100 μg/L) and C60 (C60–1 mg/L) separately and in combination. Both BaP and C60 were shown to co-localize in the secondary lysosomes of the hepatopancreatic digestive cells in the digestive gland where they reduced lysosomal membrane stability (LMS) or increased membrane permeability, while BaP also induced increased lysosomal lipid and lipofuscin, indicative of oxidative cell injury and autophagic dysfunction. Combinations of BaP and C60 showed antagonistic effects for …

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The Potential Of Raman Spectroscopy In The Diagnosis Of Dysplastic And Malignant Oral Lesions, Ola Ibrahim, M. Toner, Steven Flint, Hugh Byrne, Fiona Lyng Feb 2021

The Potential Of Raman Spectroscopy In The Diagnosis Of Dysplastic And Malignant Oral Lesions, Ola Ibrahim, M. Toner, Steven Flint, Hugh Byrne, Fiona Lyng

Articles

Early diagnosis, treatment and/or surveillance of oral premalignant lesions are important in preventing progression to oral squamous cell carcinoma (OSCC). The current gold standard is through histopathological diagnosis, which is limited by inter and intra observer and sampling errors. The objective of this work was to use Raman spectroscopy to discriminate between benign, mild, moderate and severe dysplasia and OSCC in formalin fixed paraffin preserved (FFPP) tissues. The study included 72 different pathologies from which 17 were benign lesions, 20 mildly dysplastic, 20 moderately dysplastic, 10 severely dysplastic and 5 invasive OSCC. The glass substrate and paraffin wax background were …

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Electromagnetic Pollution Alert: Microwave Radiation And Absorption In Human Organs And Tissues, Nantakan Wongkasem Feb 2021

Electromagnetic Pollution Alert: Microwave Radiation And Absorption In Human Organs And Tissues, Nantakan Wongkasem

Electrical and Computer Engineering Faculty Publications

Electromagnetic radiation from communication and electronic devices, networks, systems and base stations has drawn concern due to excessive global usage with increasing power and operating frequency level. Numerous previous researches only focus on how the radiation from certain frequency ranges of particular devices could harm specific human organs and tissues, resulting in distinct symptoms. In this research, electromagnetic propagation and properties in fourteen human organs and tissues were analyzed and investigated based on the organs and tissues’ electromagnetic and mechanical parameters, and chemical composition. Counting the organs and tissues as electromagnetic materials, their permittivity and conductivity, computed by a 4-Cole-Cole …

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The Comparative Psychology Of Intelligence: Macphail Revisited, Michael Colombo, Damian Scarf, Thomas R. Zentall Feb 2021

The Comparative Psychology Of Intelligence: Macphail Revisited, Michael Colombo, Damian Scarf, Thomas R. Zentall

Psychology Faculty Publications

No abstract provided.

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A Molecular Tetrahedral Cobalt-Seleno-Based Complex As An Efficient Electrocatalyst For Water Splitting, Ibrahim Munkaila Abdullahi, Jahangir Masud, Polydoros Chrisovalantis Ioannou, Eleftherios Ferentinos, Panayotis Kyritsis, Manashi Nath Feb 2021

A Molecular Tetrahedral Cobalt-Seleno-Based Complex As An Efficient Electrocatalyst For Water Splitting, Ibrahim Munkaila Abdullahi, Jahangir Masud, Polydoros Chrisovalantis Ioannou, Eleftherios Ferentinos, Panayotis Kyritsis, Manashi Nath

Chemistry Faculty Research & Creative Works

The cobalt-seleno-based coordination complex, [Co{(SePiPr2)2N}2], is reported with respect to its catalytic activity in oxygen evolution and hydrogen evolution reactions (OER and HER, respectively) in alkaline solutions. An overpotential of 320 and 630 mV was required to achieve 10 mA cm-2 for OER and HER, respectively. The overpotential for OER of this CoSe4-containing complex is one of the lowest that has been observed until now for molecular cobalt(II) systems, under the reported conditions. In addition, this cobalt-seleno-based complex exhibits a high mass activity (14.15 A g-1) and …

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Compoundhetvip: Compound Heterozygous Variant Identification Pipeline, Dustin B. Miller, Stephen R. Picollo Feb 2021

Compoundhetvip: Compound Heterozygous Variant Identification Pipeline, Dustin B. Miller, Stephen R. Picollo

Faculty Publications

Compound Heterozygous ( CH) variant identification requires distinguishing maternally from paternally derived nucleotides, a process that requires numerous computational tools. Using such tools often introduces unforeseen challenges such as installation procedures that are operating-system specific, software dependencies that must be installed, and formatting requirements for input files. To overcome these challenges, we developed Compound Heterozygous Variant Identification Pipeline (CompoundHetVIP), which uses a single Docker image to encapsulate commonly used software tools for file aggregation ( BCFtools or GATK4), VCF liftover ( Picard Tools), joint-genotyping ( GATK4), file conversion ( Plink2), phasing ( SHAPEIT2, Beagle …

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Child Obesity Moderates The Association Between Poverty And Academic Achievement, Ashley W. Kranjac, Dinko Kranjac Feb 2021

Child Obesity Moderates The Association Between Poverty And Academic Achievement, Ashley W. Kranjac, Dinko Kranjac

Sociology Faculty Articles and Research

Childhood overweight and obesity are major public health problems in the United States. Children who experience poverty are 1.5 times more likely to suffer with overweight and 1.6 times more likely to have obesity. The extent to which overweight or obesity exacerbates the negative influence of socioeconomic inequality on child academic outcomes has not yet been examined. We estimated the effect of poverty on math and reading achievement trajectories using the Early Childhood Longitudinal Study (ECLS) Kindergarten class of 1998−1999 survey data and multilevel growth curve modeling techniques. Our findings indicate that the impact of obesity status is more pronounced …

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Sequencing Of 53,831 Diverse Genomes From The Nhlbi Topmed Program, Daniel Taliun, Daniel N. Harris, Michael D. Kessler, Jedidiah Carlson, John Blangero, Joanne E. Curran, Michael C. Mahaney, Harald H. H. Goring, Ravindranath Duggirala, Juan M. Peralta Feb 2021

Sequencing Of 53,831 Diverse Genomes From The Nhlbi Topmed Program, Daniel Taliun, Daniel N. Harris, Michael D. Kessler, Jedidiah Carlson, John Blangero, Joanne E. Curran, Michael C. Mahaney, Harald H. H. Goring, Ravindranath Duggirala, Juan M. Peralta

School of Medicine Publications

The Trans-Omics for Precision Medicine (TOPMed) programme seeks to elucidate the genetic architecture and biology of heart, lung, blood and sleep disorders, with the ultimate goal of improving diagnosis, treatment and prevention of these diseases. The initial phases of the programme focused on whole-genome sequencing of individuals with rich phenotypic data and diverse backgrounds. Here we describe the TOPMed goals and design as well as the available resources and early insights obtained from the sequence data. The resources include a variant browser, a genotype imputation server, and genomic and phenotypic data that are available through dbGaP (Database of Genotypes and …

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The Rac-Gef Tiam1 Promotes Dendrite And Synapse Stabilization Of Dentate Granule Cells And Restricts Hippocampal-Dependent Memory Functions, Jinxuan Cheng, Federico Scala, Francisco A Blanco, Sanyong Niu, Karen Firozi, Laura Keehan, Shalaka Mulherkar, Emmanouil Froudarakis, Lingyong Li, Joseph G Duman, Xiaolong Jiang, Kimberley F Tolias Feb 2021

The Rac-Gef Tiam1 Promotes Dendrite And Synapse Stabilization Of Dentate Granule Cells And Restricts Hippocampal-Dependent Memory Functions, Jinxuan Cheng, Federico Scala, Francisco A Blanco, Sanyong Niu, Karen Firozi, Laura Keehan, Shalaka Mulherkar, Emmanouil Froudarakis, Lingyong Li, Joseph G Duman, Xiaolong Jiang, Kimberley F Tolias

Faculty, Staff and Students Publications

The dentate gyrus (DG) controls information flow into the hippocampus and is critical for learning, memory, pattern separation, and spatial coding, while DG dysfunction is associated with neuropsychiatric disorders. Despite its importance, the molecular mechanisms regulating DG neural circuit assembly and function remain unclear. Here, we identify the Rac-GEF Tiam1 as an important regulator of DG development and associated memory processes. In the hippocampus, Tiam1 is predominantly expressed in the DG throughout life. Global deletion of Tiam1 in male mice results in DG granule cells with simplified dendritic arbors, reduced dendritic spine density, and diminished excitatory synaptic transmission. Notably, DG …

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Nutrients Intake By The Ile‐De‐France Lambs Fed Up With Diets Containing Sugar Cane Forage Variety Or Corn Silage, A. G. Silva Sobrinho, G. M. B. Moreno, A. G. Leão, C. M. B. Loureiro, A. A. M. Sampaio Feb 2021

Nutrients Intake By The Ile‐De‐France Lambs Fed Up With Diets Containing Sugar Cane Forage Variety Or Corn Silage, A. G. Silva Sobrinho, G. M. B. Moreno, A. G. Leão, C. M. B. Loureiro, A. A. M. Sampaio

IGC Proceedings (1977-2023)

No abstract provided.

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So42- Uptake And Its Assimilation In The Different Genotypes Of Rape On The S‐Deficient, Lushen Li, Yulan Jin, Bok-Rye Lee, Woo-Jin Jung, Tae-Hwan Kim Feb 2021

So42- Uptake And Its Assimilation In The Different Genotypes Of Rape On The S‐Deficient, Lushen Li, Yulan Jin, Bok-Rye Lee, Woo-Jin Jung, Tae-Hwan Kim

IGC Proceedings (1977-2023)

No abstract provided.

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Rising To The Challenge: Managed Retreat And The Taking Clause In Maine's Climate Change Era, Maye C. Emlein Feb 2021

Rising To The Challenge: Managed Retreat And The Taking Clause In Maine's Climate Change Era, Maye C. Emlein

Maine Law Review

It is a near scientific certainty that sea levels will rise between one and eight feet by the end of the century. This will wreak havoc on our infrastructure, ecology, and public health, and cause an unquantifiable amount of economic damage. Given the inevitability of sea level rise, state and local governments must facilitate the managed retreat of people and property away from vulnerable coastal areas. However, governments’ ability to facilitate managed retreat comes head-to-head with the Takings Clauses of the United States and Maine Constitutions, which state that the government may not take private property without paying just compensation. …

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