Digital Commons Network^™

Effects Of Critical Environmental Factors On The Antimicrobial Activity Of Ε-Poly- L-Lysine, Zhenjie Liu, Peihao Huang, Shu Chen, Shun Rong, Feiting Peng, Ling Chen, Weipeng Guo

Journal of Food Science and Biotechnology

[Objective ] This study explored the effects of critical environmental factors [water activity (aw),pH,and temperature ] on the antimicrobial activity of ε-poly- L-lysine (ε-PL),aiming to provide a basis for the application of ε-PL.[Method ] With Staphylococcus aureus as an indicator strain,the micro-broth dilution and agar dilution methods as well as antimicrobial growth kinetics were utilized to determine the antimicrobial activity of ε-PL.The protein leakage assay was employed to evaluate the bacterial membrane disruption activity of ε-PL.Live/Dead fluorescence staining was performed to observe the bacterial membrane permeability.[Result ] The minimum inhibitory mass concentration (MIC ) of ε-PL against Staphylococcus aureus was …

Probiotic Properties Of Three Strains Of Lactobacillus And Their Application In Corn Husk Fermentation, Bo Zhai, Quanxian Shu, Xiaoyan Yang, Yin Mao, Yu Deng, Yunying Zhao

Journal of Food Science and Biotechnology

[Objective ] This study aims to improve the utilization of maize resources and address the shortage of feed resources.[Method ] The intestinal colonization capacity,tolerance,and antibacterial properties of three Lactobacillus strains,Lactobacillus paracasei ZB- 1 (ZB-1),L.paracasei DY- 2 (DY-2),and L.rhamnosus DY- 4 (DY-4) were evaluated.The most suitable strain for fermenting cornhusks was identified,and its fermentation process was optimized.[Result ] ZB-1 exhibited higher intestinal colonization ability and antibacterial properties than DY- 2 and DY- 4.The antibacterial mechanism of ZB- 1 was likely driven by the action of organic acids in an acidic environment and certain protein-based antimicrobial substances.The fermentation conditions for ZB- 1 …

Diversity Of Fungi On The Surfaces Of Grapes And Raisins In Turpan , Xinjiang, Lei Sun, Laifang Qi, Qiuyan Liang, Jinxuan Han, Tianli Fan, Yuhua Ma

Journal of Food Science and Biotechnology

[Objective ] This study aims to understand the potential harmful fungi that may affect the quality of raisins during the drying process of grapes from Turpan,Xinjiang and to explore the relationships between varieties and the fungal community structure and diversity on the surfaces of grapes and raisins.[Method ] Four popular grape varieties (‘Thompson Seedles s’,‘Boert e’,‘Xiangfe i’,and ‘Seedless Blac k’) in a grapery in Turpan were selected as research objects.The fungal diversity on the surfaces of grapes and raisins was analyzed via high-throughput sequencing.[Result ] The dominant fungal phyla on the surfaces of grapes and raisins were Ascomycota and Basidiomycota.The …

Regulatory Effects Of Hesperetin And Eriocitrin On Gut Microbiota In An In Vitro Simulation Model, Zeren Cheng, Xia Meng, Kejing Tang, Ling Shen, Qing Gu, Ping Li

Journal of Food Science and Biotechnology

[Objective ] This study aims to compare the effects of hesperetin and eriocitrin on the gut microbiota in different enterotypes.[Method ] An in vitro gut fermentation model was established,which was combined with 16S rRNA high-throughput sequencing and gas chromatography-mass spectrometry (GC-MS ) technique to evaluate the regulatory effects of the two flavonoids on the gut microbiota in different enterotypes.[Result ] After fermentation,both flavonoids significantly reduced the Firmicutes-to-Bacteroidota ratio (F/B ratio ) in terms of relative abundance at the phylum level in enterotype Bacteroides and enterotype Prevotella.At the genus level,pro-inflammatory bacteria including Paeniclostridium and Sutterella showed decreased relative abundance in treatment …

Effects Of Ultrasound-Assisted Enzymatic Extraction On The Physical And Chemical Properties Of Tortoise Shell Collagen, Xiong He, Rongxing Li, Shaotong Jiang, Jianfeng Lu, Lin Lin

Journal of Food Science and Biotechnology

[Objective ] The effects of different extraction methods on the yield,purity,structural characteristics,and physicochemical properties of tortoise shell collagen were investigated.[Method ] The ultrasound-assisted enzymatic method,acid method,and enzymatic method were used to extract collagen from tortoise shell powder.[Result ] The yield and purity of tortoise shell collagen extracted by ultrasound-assisted enzymatic method were 2.29% and 85.65%,respectively,significantly higher than those extracted by acid method (0.78% and 73.15%) and enzymatic method (1.77% and 75.63%).Ultraviolet absorption spectroscopy,infrared absorption spectroscopy,circular dichroism spectroscopy,and electrophoresis profiles showed that collagens extracted from tortoise shell by three methods were all type I collagen and retained intact triple helix structures.X-ray …

2025-10-15 Seeds Of Change: How Seattle Students Are Growing Community Through Urban Farming, Fatima Ali

The Spectator Online

No abstract provided.

Fall 2025 Environmental Sciences Seminar Series, Jessica Gersony, Jessica Gersony

NRESS Seminars

The field of ecology contains systemic issues and inequalities due to a history of exclusionary forces (e.g. colonialism). In response, there is a push to reimagine research labs outside of these forces. In this talk, Gersony will present the PLACE (PLant physiology, Art, and Community Engagement) lab’s artistic and scientific exploration of northeastern tree responses to climate change, and also discuss the lab’s broader project of reimagining a new way forward centered around joy, art, and community.

Justice Impacted Mothers: An Autoethnographic Study Exploring The Impacts Of Quality Prison Visitation With Children, Sarah E. Gore

PSU McNair Scholars Online Journal

This study explores the impacts of in-person visitation at correctional facilities and how the quality of this contact affects relationships between justice impacted mothers and their children. Little is known about these nuanced lived experiences as revealed by qualitative data and from someone who is mothering during incarceration. The literature on maternal incarceration is vast, but relies heavily on quantitative data. Existing research indicates facility visits, particularly those of high quality, offer constructive benefits such as reductions in maternal recidivism rates. However, separation during incarceration has shown higher risks for adolescent substance abuse, behavioral, and academic struggles. This study expands …

The Lumberjack, October 15, 2025

Cal Poly Humboldt's Student Newspaper

The student newspaper of Humboldt State University.

Commonwealth Times 2025-10-15

Commonwealth Times, 1969-

No abstract provided.

College Of Liberal Arts Faculty Bylaws 2025-2026, College Of Liberal Arts Faculty, Rollins College

College of Liberal Arts Bylaws

No abstract provided.

Hydralazine Inhibits Cysteamine Dioxygenase To Treat Preeclampsia And Senesce Glioblastoma, Kyosuke Shishikura, Jiasong Li, Yiming Chen, Nate R. Mcknight, Thomas P. Keeley, Katelyn A. Bustin, Eric W. Barr, Snehil R. Chilkamari, Mahaa Ayub, Sun Woo Kim, Zongtao Lin, Ren-Ming Hu, Kelly Hicks, Xie Wang, Donald M. O'Rourke, J. Martin Bollinger, Zev A. Binder, William H. Parsons, Kirill A. Martemyanov, Aimin Liu, Megan L. Matthews

SKMC Student Presentations and Publications

Hydralazine (HYZ), a treatment for preeclampsia and hypertensive crisis, is listed by the World Health Organization as an essential medicine. Its mode of action has remained unknown through its seven decades of clinical use. Here, we identify 2-aminoethanethiol dioxygenase (ADO), a key mediator of targeted protein degradation, as a selective HYZ target. The drug chelates ADO's metallocofactor and can alkylate one of its ligands. The resultant inactivation stabilizes regulators of G protein signaling (RGS4 and RGS5) that ADO normally marks for proteolysis, explaining the drug's vasodilatory activity and comporting with observations of diminished RGS levels in both clinical preeclampsia and …

Daily Eastern News: October 15, 2025, Eastern Illinois University

Daily Eastern News: 2025-2026

No abstract provided.

Forecasting Monthly Rainfall In The Pirmam Area, Kurdistan Region, Iraq: A Machine Learning Approach., Sakar Muhamad, Rawshan Ali

Polytechnic Journal

Agriculture, emergency preparedness, and water resource management all depend on accurate rainfall forecasts. This study investigates how well machine learning models predict monthly rainfall in the Kurdistan Region of Iraq, specifically in the Pirmam area. Historical weather data was analyzed using a variety of models, such as Artificial Neural Networks (ANN), Adaptive Neuro-Fuzzy Inference System (ANFIS), Multiple Linear Regression (MLR), Least Absolute Shrinkage and Selection Operator (LASSO), Elastic Net (ELNET), and Ridge Regression. Statistical measures including Nash-Sutcliffe Efficiency (NSE), Mean Bias Error (MBE), Normalized Root Mean Squared Error (nRMSE), Coefficient of Determination (R2), and Root Mean Squared Error (RMSE) were …

Understanding Callus Types In Maize By Genetic Mapping And Transcriptional Profiling, Guifang Lin, Yan Liu, Tej Man Tamang, Yang Qin, Mingxia Zhao, Hairong Wei, Et. Al.

Michigan Tech Publications

Plant transformation efficiency is highly dependent on species, individual genotypes, and tissue types. In maize, immature embryos are regularly used for transformation. The process relies heavily on callus development, as it is intricately associated with somatic embryogenesis and subsequent plant regeneration, both of which directly affect transformation efficiency. Immature embryos of the segregation progeny derived from the two inbred parents, a transformation-amenable line A188 and a recalcitrant line B73, can be cultured to form two primary callus types: Type I and Type II. The Type II callus grows faster and is a favorable type for regeneration. Here, Type I and …

Twenty Minutes Of Corsi Block Tapping Task Training Does Not Improve Mental Rotation In Adults With Stroke, Sarah A. Kettlety, Giuliet L. Kibler, Andrew Hooyman, Christina K. Holl, Sydney Y. Schaefer, Kristan A. Leech

Physical Therapy Faculty Articles and Research

Background: Visuospatial function is commonly impaired post-stroke and is associated with motor learning and recovery. A single, twenty-minute Corsi Block Tapping Task (CBTT) training session improved visuospatial function in young neurotypical adults; however, it is unclear whether this training would improve visuospatial function in adults with stroke.

Objective: To understand if a single, twenty-minute CBTT training session improved visuospatial function in adults with stroke compared to a no-training control group of adults with stroke.

Methods: Participants post-stroke were assigned to one of two groups. The training group completed twenty minutes of computerized CBTT training. The control group completed a survey …

Exploring The World Of Medical Exoskeleton Robots: A Classification Guide, Javlonbek Rakhmatillaev, Vytautas Bučinskas

Technical science and innovation

This article describes the classification of exoskeletons. This classification is based on the use of exoskeletons in the medical field, shape, power source, generation, parts related to the human body, structural material, and control forms based on sensor and actuator devices. In addition, examples of each category are given. The main goal is to comprehensively evaluate medical exoskeletons, pay special attention to their functions and goals, conduct scientific research, and further develop these devices. As a result, a completely new type of classification of medical exoskeletons was developed. The developed new type of classification serves as an important guide in …

Topology Across Scales On Heterogeneous Cell Data, M. Torras-Pérez, Iris Yoon , '13, P. Weeratunga, L.-P. Ho, H. M. Byrne, U. Tillmann, H. A. Harrington

Mathematics & Statistics Faculty Works

Multiplexed imaging allows multiple cell types to be simultaneously visualised in a single tissue sample, generating unprecedented amounts of spatially-resolved, biological data. In topological data analysis, persistent homology provides multiscale descriptors of “shape" suitable for the analysis of such spatial data. Here we propose a novel visualisation of persistent homology (PH) and fine-tune vectorisations thereof (exploring the effect of different weightings for persistence images, a prominent vectorisation of PH). These approaches offer new biological interpretations and promising avenues for improving the analysis of complex spatial biological data especially in multiple cell type data. To illustrate our methods, we apply them …

Structural And Biological Properties Of Chitosan/Copper Polymetallic Complexes Synthesized From Apis Mellifera-Derved Chitosan, Dilnoza Sohibovna Isomitdinova, Gulnora Akmalovna Ikhtiyarova, Nazira Madusmanovna Kuchkarbayeva, Nafisa Akhrorovna Ergasheva

Technical science and innovation

In this study, a chitosan/copper (Ch/Cu²⁺) polymetallic complex was synthesized from chitosan obtained by the cryogenic method from Apis mellifera bees. The structural and physicochemical properties of the complex were investigated using FTIR, UV-Vis, XRD, TGA, and DLS analyses. FTIR spectra showed shifts in absorption bands at 1400-1339 cm⁻¹ and 1640-1550 cm⁻¹, confirming the coordination of Cu²⁺ ions with amino and hydroxyl groups. UV-Vis spectra revealed absorption peaks in the 410-540 nm range, while XRD analysis indicated new crystalline peaks at 2θ = 24°, 27°, and 37°. Thermal analysis demonstrated high thermal stability of the complex, and DLS confirmed a …

Improvement Of Ultrasonic-Convective Equipment And Beetroot (Beta Vulgaris L.) Drying Process, Jasur Esirgapovich Safarov, Shakhnoza Abduvaxitovna Sultanova, R. M. Najafli

Technical science and innovation

In the world, the air-dried food market is seeing rapid expansion, valued at USD 103.26 billion in 2021, out of which the Asia Pacific region consumed the maximum amount. The freeze-dried vegetable and fruit market is predicted to reach USD 132.7 billion by 2027. Processed vegetables are also exported to a large extent from India. Uzbekistan recorded excellent development in agriculture in 2024, with record harvests, better yields, and use of advanced machinery. Azerbaijan also demonstrated good agriculture growth and export performance. Beetroot has now been identified as a functional food containing bioactive compounds like betaines and dietary fiber that …

Evaluation Of Hypolipidemic And Hypoglycemic Effects Of Dillenia Indica L. On Alloxan-Induced Diabetic Rats, Md Mahfuj Alam Siddiq

Student Scholarship

Context: Dillenia indica L. a tropical fruit-bearing plant native to South and Southeast Asia, has attracted scientific interest due to its rich phytochemical composition and potential therapeutic benefits in managing diabetes, lipid disorders, and oxidative stress. Objective: The objective of this study was to investigate the potential antidiabetic and lipid-lowering properties of D. indica fruit and bark extracts in a rat model of alloxan-induced type 2 diabetes. Methods: Diabetes was induced in rats using an intraperitoneal injection of alloxan (160 mg/kg) after a 12-hour fast. The chloroform fractions of D. indica fruit and bark (200 mg/kg) were administered intraperitoneally, with …

Estrogen-Related Receptor Alpha Promotes Skeletal Muscle Regeneration And Mitigates Muscular Dystrophy, Thi Thu Hao Nguyen, Ya Xiang Huang, Svitlana Poliakova, Citu Citu, Eira Mann, Danesh H Sopariwala, Zhongming Zhao, Ashok Kumar, Vihang A Narkar

The Brown Foundation: Institute of Molecular Medicine

Skeletal muscle regeneration in chronic muscle diseases such as Duchenne Muscular Dystrophy (DMD) has remained clinically unsurmountable. Estrogen‐related receptor alpha (ERRα) plays a critical role in adult skeletal muscle metabolism and exercise fitness. Whether ERRα activation can drive muscle regeneration and mitigate dystrophy in DMD is not known. We have investigated ERRα signaling in pre‐clinical models of acute muscle injury and DMD. ERRα is induced in differentiating C2C12 myoblast and regenerating muscle. ERRα silencing suppressed proliferation and differentiation in C2C12 myoblasts. RNA sequencing revealed that angiogenic factor and proliferation genes were downregulated by ERRα knockdown in proliferating cells, whereas oxidative …

Introducing Mcodegpt As A Zero-Shot Information Extraction From Clinical Free Text Data Tool For Cancer Research, Kai Zhang, Tongtong Huang, Bradley A Malin, Travis Osterman, Qi Long, Xiaoqian Jiang

Faculty, Staff and Student Publications

Background: The vast amount of natural language clinical notes about patients with cancer presents a challenge for efficient information extraction, standardization, and structuring. Traditional NLP methods require extensive annotation by domain experts for each type of named entity and necessitate model training, highlighting the need for an efficient and accurate extraction method.

Methods: This study introduces a tool based on the Large Language Model (LLM) for zero-shot information extraction from cancer-related clinical notes into structured data aligned with the minimal Common Oncology Data Elements (mCODE™) structure. We utilize the zero-shot learning capabilities of LLMs for information extraction, eliminating the need …

Tacscope: A Miniaturized Vision-Based Tactile Sensor For Surgical Applications, Md Rakibul Islam Prince, Sheeraz Athar, Pokuang Zhou, Yu She

School of Industrial Engineering Faculty Publications

The lack of tactile feedback in robot-assisted minimally invasive surgery (RMIS) limits surgeons’ ability to palpate tissues, a critical technique for locating abnormalities such as tumors. To address this challenge, we introduce TacScope, a novel, vision-based tactile sensor leveraging the magnification properties of a spherical-surface elastomer to provide tactile feedback for advanced clinical applications. TacScope features a robust, low-cost, and easyly fabricate design, enabling seamless integration into surgical robotic setups. It reconstructs high-resolution 3D geometry from variations in particle-density distribution across its elastomer surface, requiring only a single image for calibration. The curved elastomer membrane alters particle-density distribution under …

“I Just Need Another Set Of Eyes”: Understanding Students’ Idea Of The Writing Center, Isabelle M. Lundin, Neal Lerner

The Writing Center Journal

In this article, we describe writing center clients’ “idea” of the writing center based on interviews with 26 writing center users and qualitative coding of interview transcripts. Participants’ constructs of the writing center provide a lens to better understand how they perceive writing as an activity, the “writing culture” of the institution, the role of the writing center in their writing processes, and, ultimately, if they see writing centers in the way we would expect them to. The tensions we derived from our data are (1) between who and what tutors are and offer: discipline-specific expertise (including the disciplines of …

Evaluating Platinum, Gold, Glassy Carbon, And Graphite Anodes For Chlorine Evolution In Molten Calcium Chloride Salt, Cameron Vann, Shelssie Klvacek, Carlos Mejia, Devin Rappleye

Faculty Publications

The chlorine evolution reaction (CER) in molten CaCl₂ plays a critical role in high-temperature electrochemical processes, including chlorination, metal refining, and used nuclear fuel treatment. This study evaluates the performance of gold (Au), platinum (Pt), glassy carbon (GC), and graphite anodes for the CER under consistent electrochemical conditions. Anode performance was assessed based on chlorine (Cl₂) gas evolution, material robustness, and kinetic parameters. Cl₂ generation was directly confirmed using quadrupole mass spectrometry for Pt, GC, and graphite anodes. GC and graphite demonstrated stable and sustained CER activity. Pt and Au were shown to have significant mass …

Alterations Of The Upper Respiratory Microbiome Among Children Living With Hiv Infection In Botswana, Sweta M Patel, John Farirai, Mohamed Z Patel, Sifelane Boiditswe, Leabaneng Tawe, Shimane Lekalake, Mogomotsi Matshaba, Andrew P Steenhoff, Tonya Arscott-Mills, Kristen A Feemster, Samir S Shah, Nathan Thielman, Coleen K Cunningham, Lawrence A David, David M Murdoch, Matthew S Kelly

Faculty, Staff and Students Publications

Children living with HIV (CLWH) are at high risk of colonization and infection by respiratory pathogens, though this risk can be reduced by other microbes in the upper respiratory microbiome. The impact of HIV infection on the pediatric upper respiratory microbiome is poorly understood, and we sought to address this knowledge gap by identifying associations between HIV infection and the nasopharyngeal microbiomes of Batswana children. We enrolled Batswana CLWH (< 5 years) and age- and sex-matched HIV-exposed, uninfected and HIV-unexposed, uninfected children in a cross-sectional study. We used shotgun metagenomic sequencing to compare nasopharyngeal microbiomes by HIV status. Among the 143 children in this study, HIV and HIV-associated immunosuppression were associated with alterations in nasopharyngeal microbiome composition, including lower abundances of Corynebacterium species associated with resistance to bacterial pathogen colonization. These findings suggest that the upper respiratory microbiome may contribute to the high risk of respiratory infections among CLWH.

Sub-Ciliary Localization Of Cep290 And Effects Of Its Loss In Mouse Photoreceptors During Development, Abigail R. Moye, Michael A. Robichaux, Melina A. Agosto, Alexandre P. Moulin, Alexandra Graff-Meyer, Carlo Rivolta, Theodore G. Wensel

Faculty, Staff and Students Publications

No abstract provided.

Differential Bk Channel Potentiation By Vanzacaftor Enantiomers Enables Therapy For Modulator-Ineligible People With Cystic Fibrosis, Nathalie Baumlin, Sumedha Gunewardena, Scott H Randell, Frank T Horrigan, Matthias Salathe

Faculty, Staff and Students Publications

No abstract provided.

Stereoelectroencephalography Reveals Neural Signatures Of Multisensory Integration In The Human Superior Temporal Sulcus During Audiovisual Speech Perception, Yue Zhang, John F Magnotti, Xiang Zhang, Zhengjia Wang, Yingjia Yu, Kathryn A Davis, Sameer A Sheth, H Isaac Chen, Daniel Yoshor, Michael S Beauchamp

Faculty, Staff and Students Publications

Human speech perception is multisensory, integrating auditory information from the talker's voice with visual information from the talker's face. BOLD fMRI studies have implicated the superior temporal gyrus (STG) in processing auditory speech and the superior temporal sulcus (STS) in integrating auditory and visual speech, but as an indirect hemodynamic measure, fMRI is limited in its ability to track the rapid neural computations underlying speech perception. Using stereoelectroencephalography (sEEG) electrodes, we directly recorded from the STG and STS in 42 epilepsy patients (25F, 17M). Participants identified single words presented in auditory, visual, and audiovisual formats with and without added auditory …