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The Diamond, February 12, 2021, Dordt University

Dordt Diamond

• Front Page: City Council Invites Feedback for Future Dome Sports Facility; New Semester, New Regulations; Cine-Rupture Fills the Prairie Grass Vacuum
• News: Changes for the Commons; The Stock Market Prevails; Dordt Posts Record Total Enrollment for a Spring Semester
• Sports: The Super Bowl Turns Fifty-Five; Dordt Baseball Kicks Off Season in Kansas; NFL Quarterback Dominos Start to Fall
• Art & Entertainment: WandaVision Fever; Disenchantment Season Three: Strange But Enjoyable; Attack on Titan: An Ode to Freedom
• Opinion: Dordt University's COVID-19 Dashboard; OMORI: Welcome to the White Space; East Campus is a Scam; Valentine's Day …

Impact D’Un Stress Thermique Représentatif Des Milieux De Travail Sur L’Absorption Pulmonaire Et La Toxicocinétique De Trois Solvants Organiques, Axelle Marchand, Pierre Brochu, Jessie Ménard, Sami Haddad

Rapports de recherche scientifique

Plusieurs des changements physiologiques associés à la thermorégulation peuvent influencer la cinétique des substances chimiques dans le corps humain, comme la ventilation alvéolaire et la redistribution du débit sanguin aux organes. Si certaines mesures préventives peuvent permettre de protéger les travailleurs contre les effets directs de la chaleur, elles ne permettent toutefois pas d’empêcher les processus de thermorégulation de prendre place. Une exposition concomitante à la chaleur et aux substances chimiques volatiles peut donc entraîner des variations dans l’absorption par inhalation et dans la cinétique de ces substances, biaisant ainsi l’évaluation des données de biosurveillance.

Dans cette étude, l’influence de …

Under Pressure: Hydrogel Swelling In A Granular Medium, Jean François Louf, Nancy B. Lu, Margaret G. O'Connell, H. Jeremy Cho, Sujit S. Datta

Mechanical Engineering Faculty Research

Copyright © 2021 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works. Distributed under a Creative Commons Attribution NonCommercial License 4.0 (CC BY-NC). Hydrogels hold promise in agriculture as reservoirs of water in dry soil, potentially alleviating the burden of irrigation. However, confinement in soil can markedly reduce the ability of hydrogels to absorb water and swell, limiting their widespread adoption. Unfortunately, the underlying reason remains unknown. By directly visualizing the swelling of hydrogels confined in three-dimensional granular media, we demonstrate that the extent of hydrogel swelling is …

Immunomodulatory Effects Of Azithromycin Revisited: Potential Applications To Covid-19, Vincent J. Venditto, Dalia Haydar, Ahmed K. Abdel-Latif, John C. Gensel, Michael I. Anstead, Michelle G. Pitts, Jarrod W. Creameans, Timothy J. Kopper, Chi Peng, David J. Feola

Pharmaceutical Sciences Faculty Publications

The rapid advancement of the COVID-19 pandemic has prompted an accelerated pursuit to identify effective therapeutics. Stages of the disease course have been defined by viral burden, lung pathology, and progression through phases of the immune response. Immunological factors including inflammatory cell infiltration and cytokine storm have been associated with severe disease and death. Many immunomodulatory therapies for COVID-19 are currently being investigated, and preliminary results support the premise of targeting the immune response. However, because suppressing immune mechanisms could also impact the clearance of the virus in the early stages of infection, therapeutic success is likely to depend on …

Plenary Session 2 - The Impact Of “Impact” In Ip Scholarship: Citations, Downloads And Why We (Should/Don’T) Care, Christine Farley, Gregory N. Mandel, Leah Chan Grinvald, Kimberlee Weatherall, Paul Heald

Presentations

By American University Washington College of Law, Texas A&M University School of Law, and University of Utah S.J. Quinney College of Law.

Protecting Intestinal Microenvironment Alleviates Acute Graft-Versus-Host Disease, Zhengcan Zhou, Ting Shang, Xiurong Li, Hongyan Zhu, Yu-Bo Qi, Xin Zhao, Xi Chen, Zhe-Xin Shi, Guixiang Pan, Yue-Fei Wang, Guanwei Fan, Xiumei Gao, Yan Zhu, Benjamin Feng

Peer Reviewed Articles

Acute gut graft-versus-host disease (aGVHD) is a leading threat to the survival of allogeneic hematopoietic stem cell transplantation (allo-HSCT) recipients. Abnormal gut microbiota is correlated with poor prognosis in allo-HSCT recipients. A disrupted intestinal microenvironment exacerbates dysbiosis in GVHD patients. We hypothesized that maintaining the integrity of the intestinal barrier may protect gut microbiota and attenuate aGVHD. This hypothesis was tested in a murine aGVHD model and an in vitro intestinal epithelial culture. Millipore cytokine array was utilized to determine the expression of proinflammatory cytokines in the serum. The 16S rRNA sequencing was used to determine the abundance and diversity …

Aesthetically Designing Video-Call Technology With Care Home Residents: A Focus Group Study, Sonam Zamir, Felicity Allman, Catherine Hagan Hennessy, Adrian Haffner Taylor, Ray Brian Jones

Peninsula Medical School

BackgroundVideo-calls have proven to be useful for older care home residents in improving socialization and reducing loneliness. Nonetheless, to facilitate the acceptability and usability of a new technological intervention, especially among people with dementia, there is a need for user-led design improvements. The current study conducted focus groups with an embedded activity with older people to allow for a person-centered design of a video-call intervention.MethodsTwenty-eight residents across four care homes in the South West of England participated in focus groups to aesthetically personalize and ‘dress-up’ the equipment used in a video-call intervention. Each care home was provided with a ‘Skype …

Nitrate Uptake Enhanced By Availability Of Dissolved Organic Matter In Tropical Montane Streams, Bianca M. Rodriguez-Cardona, Adam S. Wymore, William H. Mcdowell

NRESS Publications

Tropical forests store large amounts of Earth’s terrestrial C, but many tropical montane streams have low dissolved organic matter (DOM). This low availability of energy likely limits certain pathways of inorganic N uptake, as evidenced by the high rates of nitrification and predominance of nitrate (NO3−) in the total pool of dissolved N seen in many tropical montane forests. To explore the influence of DOM availability on tropical stream N cycling, we performed nutrient pulse additions of NO3− with or without an added C source (acetate or urea) in streams of the Luquillo Experimental Forest, Puerto Rico. In the absence …

Can Track And Field’S Governing Body Ban Female Runners From Competing In The U.S. Because Of High Testosterone Levels?, Katz, Ronald S., Luckinbill, Robert W.

Santa Clara Law Review

This article explores the applicability, if any, in the United States of a decision rendered by a private sports arbitration organization in Lausanne, Switzerland: the Court of Arbitration for Sport (CAS). The decision validated regulations of World Athletics—the private organization that governs track and field internationally—which had the effect of banning an Olympic champion, Caster Semenya of South Africa, from international competition against females because she had testosterone levels that World Athletics deemed too high. The article focuses on the fact that the CAS decision uses the law of Monaco to decide the matter. CAS specifically states that the decision …

Seizure Clusters, Seizure Severity Markers, And Sudep Risk., Manuela Ochoa-Urrea, Nuria Lacuey, Laura Vilella, Liang Zhu, Shirin Jamal-Omidi, M R Sandhya Rani, Johnson P Hampson, Mojtaba Dayyani, Jaison Hampson, Norma J Hupp, Shiqiang Tao, Rup K Sainju, Daniel Friedman, Maromi Nei, Catherine Scott, Luke Allen, Brian K Gehlbach, Victoria Reick-Mitrisin, Stephan Schuele, Jennifer Ogren, Ronald M Harper, Beate Diehl, Lisa M Bateman, Orrin Devinsky, George B Richerson, Guo-Qiang Zhang, Samden D Lhatoo

Department of Neurology Faculty Papers

Rationale: Seizure clusters may be related to Sudden Unexpected Death in Epilepsy (SUDEP). Two or more generalized convulsive seizures (GCS) were captured during video electroencephalography in 7/11 (64%) patients with monitored SUDEP in the MORTEMUS study. It follows that seizure clusters may be associated with epilepsy severity and possibly with SUDEP risk. We aimed to determine if electroclinical seizure features worsen from seizure to seizure within a cluster and possible associations between GCS clusters, markers of seizure severity, and SUDEP risk. Methods: Patients were consecutive, prospectively consented participants with drug-resistant epilepsy from a multi-center study. Seizure clusters were defined as …

Humans Long Ignored: Revisiting Nepa's Definition Of "Human Environment" In The Era Of Black Lives Matter, Travis D. Jones

Villanova Environmental Law Journal (1991 - )

No abstract provided.

The Wall That Trumps Environmental Law: A Review Of The Environmental And Legal Implications Of The U.S.-Mexico Border Wall, Olivia Merritt

Villanova Environmental Law Journal (1991 - )

No abstract provided.

Integrated Plasma Proteomic And Single-Cell Immune Signaling Network Signatures Demarcate Mild, Moderate, And Severe Covid-19, Dorien Feyaerts, Julien Hedou, Joshua Gillard, Han Chen, Eileen S. Tsai, Laura S. Peterson, Kazuo Ando, Monali Manohar, Evan Do, Gopal K.R. Chinthrajah, Christopher M. Warren, Rich Wittman, Justin G. Meyeroqitz, Edward A. Ganio, Ina A. Stelzer, Xiaoyuan Han, Franck Verdonk, Dyani K. Gaudilliere, Nilanjan Mukherjee, Amy S. Tsai, Kristen K. Rumer, Sizun Jiang, Sergio Ivan Valdes Ferrer, J. Daniel Kelly, David Furman, Nima Aghaeepour, Martin S. Angst, Scott D. Boyd, Benjamin A. Pinsky, Garry P. Nolan, Kari C. Nadeau, Brice Gaudilliere, David R. Mcilwain

All Dugoni School of Dentistry Faculty Articles

The biological determinants of the wide spectrum of COVID-19 clinical manifestations are not fully understood. Here, over 1400 plasma proteins and 2600 single-cell immune features comprising cell phenotype, basal signaling activity, and signaling responses to inflammatory ligands were assessed in peripheral blood from patients with mild, moderate, and severe COVID-19, at the time of diagnosis. Using an integrated computational approach to analyze the combined plasma and single-cell proteomic data, we identified and independently validated a multivariate model classifying COVID-19 severity (multi-class AUCtraining = 0.799, p-value = 4.2e-6; multi-class AUCvalidation = 0.773, p-value = 7.7e-6). Features of this high-dimensional model recapitulated …

Randomized Controlled Trials Of Remdesivir In Hospitalized Coronavirus Disease 2019 Patients: A Meta-Analysis, Azza Sarfraz, Zouina Sarfraz, Marcos Sanchez-Gonzalez, Jack Michel, George Michel, Odalys Frontela, Jorge Posada, Jose Cardona, Eugenio Angueira

Department of Paediatrics and Child Health

Background: The first cases of the coronavirus disease 2019 (COVID-19) were reported in Wuhan, China. No antiviral treatment options are currently available with proven clinical efficacy. However, preliminary findings from phase III trials suggest that remdesivir is an effective and safe treatment option for COVID-19 patients with both moderate and severe disease.
Objective: The aim of the present meta-analysis was to investigate whether remdesivir was effective for treating COVID-19 including reduced in-hospital adverse events, oxygen support, and mortality rates.
Methods: According to the PRISMA reporting guidelines, a review was conducted from January 1, 2020, until August 25, 2020, with MeSH …

Evidence For The Effects Of Decommissioning Man-Made Structures On Marine Ecosystems Globally: A Systematic Map Protocol, Anaëlle J. Lemasson, Antony M. Knights, Murray Thompson, Gennadi Lessin, Nicola Beaumont, Christine Pascoe, Ana M. Queirós, Louise Mcneill, Michaela Schratzberger, Paul J. Somerfield

School of Biological and Marine Sciences

Background: Numerous man-made structures (MMS) have been installed in various parts of the ocean (e.g. oil and gas structures, offshore wind installations). Many are now at, or nearing, the end of their intended life. Currently, we only have a limited understanding of decommissioning effects. In many locations, such as the North Sea, regulations restrict decommissioning options to complete removal, with little consideration of alternative management options might offer. To generate a reliable evidence-base to inform the decision-making processes pertaining to marine MMS management, we propose a wide-encompassing systematic map of published research on the ecosystem effects (including ecosystem services) of …

Organic Waste Substrates Induce Important Shifts In Gut Microbiota Of Black Soldier Fly (Hermetia Illucens L.): Coexistence Of Conserved, Variable, And Potential Pathogenic Microbes, Chrysantus M. Tanga, Jacqueline Wahura Waweru, Yosef Hamba Tola, Abel Anyega Onyoni, Fathiya M. Khamis, Sunday Ekesi, Juan C. Paredes

All Peer-Reviewed Publications

The sustainable utilization of black soldier fly (BSF) for recycling organic waste into nutrient-rich biomass, such as high-quality protein additive, is gaining momentum, and its microbiota is thought to play important roles in these processes. Several studies have characterized the BSF gut microbiota in different substrates and locations; nonetheless, in-depth knowledge on community stability, consistency of member associations, pathogenic associations, and microbe–microbe and host–microbe interactions remains largely elusive. In this study, we characterized the bacterial and fungal communities of BSF larval gut across four untreated substrates (brewers’ spent grain, kitchen food waste, poultry manure, and rabbit manure) using 16S and …

Combination Therapy: Dual Drug-Loaded Superparamagnetic Iron-Oxide Nanoparticle For Targeted Drug Delivery And Treatment Of Cancer, Himanshu Polara

Electronic Theses & Dissertations

Lung cancer is the most occurring form of cancer of all ages in the United States after breast cancer. Many treatments are currently available in the market to treat cancer, but they all have some side effects. The concept of nanomedicine-based targeted drug delivery has been developed to overcome the limitations of current treatment. The advantages of this method of treatment include biocompatibility, significant toxicity towards cancer cells, immediate drug response, and fewer side effects. For the specific treatment of A549 lung cancer cells, polyacrylic acid (PAA) coated Iron Oxide Nanoparticle (IONP) were introduced for magnetic resonance imaging (MRI) of …

Areas Of Metabolomic Exploration For Helminth Infections, Jeffrey D Whitman, Judy A Sakanari, Makedonka Mitreva

2020-Current year OA Pubs

Helminths represent a diverse category of parasitic organisms that can thrive within a host for years, if not decades, in the absence of treatment. As such, they must establish mechanisms to subsist off their hosts, evade the immune system, and develop a niche among the other cohabiting microbial communities. The complex interplay of biologically small molecules (collectively known as the metabolome) derived from, utilized by, or in response to the presence of helminths within a host is an emerging field of study. In this Perspective, we briefly summarize the current existing literature, categorize key host-pathogen-microbiome interfaces that could be studied …

Student Insights: Meet The Student Senate Leadership, Uab Heersink School Of Medicine News

Browse All News

No abstract provided.

Tiller Development Of Three Bromegrass (Bromus) Species Following Defoliation, Biligetu, B. E. Coulman

IGC Proceedings (1977-2023)

No abstract provided.

Heritability And Genetic Correlations Of Forage Yield Traits In Alfalfa (Medicago Sativa L.) For Central Valley Of Mexico, B. Alarcon‐Zuniga, R. Perdomo‐Gomez

IGC Proceedings (1977-2023)

No abstract provided.

Genetic Diversity Of Hemarthria Compressa Germplasm In Southwest China Detected By Issr Markers, Fang Li, Yan Fan, Xinquan Zhang, Xiao Ma

IGC Proceedings (1977-2023)

No abstract provided.

February Agenda, Wku Graduate Council

Graduate School

Meeting agenda which includes January 14 meeting minutes, graduate council curriculum report tracking and graduate enrollment report.

New And Noteworthy: Young Adult Literature, Ed Spicer

Michigan Reading Journal

No abstract provided.

Observations Of A Correctional Educator, Merle Davenport

Michigan Reading Journal

No abstract provided.

Explorations In Expository Writing 11, Elizabeth W. Peters

Michigan Reading Journal

No abstract provided.

New And Noteworthy Books Published In 2003, Edward A. Spicer

Michigan Reading Journal

No abstract provided.

A Summary Of The Report On Higher Education And Economic Growth, Gwen Graham

Michigan Reading Journal

No abstract provided.

Bookends: Reviews Of Young Adult Literature, Ed Spicer

Michigan Reading Journal

No abstract provided.

Bookends: Reviews Of Young Adult Literature, Ed Spicer

Michigan Reading Journal

No abstract provided.