Digital Commons Network^™

The Probability Of Spotted Lanternfly, Lycorma Delicatula (Hemiptera: Fulgoridae), Escape Differs Among Life Stages And Between Two Trapping Techniques Commonly Used By Landowners, Sticky Bands And Duct Tape., Matthew Desko, Carolyne Schiebel, Samantha Silverman, Jessica Bickel, Karen Felton, Jennifer L. Chandler

The Great Lakes Entomologist

The invasive Lycorma delicatula (White) was first identified in Pennsylvania, U.S.A. in 2014, and has since increased its range to several Eastern states. Lycorma delicatula pose a serious threat to many native species, including hardwoods and grapes, and land owners are continually seeking effective traps to control populations. Both commercially-produced Web-Cote brand sticky bands and less expensive duct tape are often used by land owners to trap L. delicatula. However, the probability of escape from these adhesives has not been formally assessed, and almost certainly differs as a function of life stage and type of adhesive used. The purpose …

Coleoptera Collected Using Three Trapping Methods At Grass River Natural Area, Antrim County, Michigan, Robert A. Haack, Bill Ruesink

The Great Lakes Entomologist

Abstract. Overall, 409 Coleoptera species (369 identified to species, 24 to genus only, and 16 to subfamily only), representing 275 genera and 58 beetle families, were collected from late May through late September 2017 at the Grass River Natural Area (GRNA), Antrim County, Michigan, using baited multi-funnel traps (210 species), pitfall traps (104 species), and sweep nets (168 species). All three collecting methods were used in three distinct habitats: a rich conifer swamp (cedar), near the edge of a red pine plantation (pine), and within a mesic northern hardwood forest (hardwoods). Additional collections were made along two trails and in …

Occurrence Of Ticks (Acari: Ixodidae) On Birds In Northwestern Lower Michigan, 2011-2019, William C. Scharf, Lisa Aukland, Gary W. Shugart, Sarah A. Hamer

The Great Lakes Entomologist

Abstract

Monitoring tick infestation of wildlife provides baseline tick

occurrence data that may have human or animal health implications. We collected 312 ticks of four species from 5,122 birds of 93 species while monitoring bird migration during 15 fall and spring seasons between 2011 and 2019 in the northern Lower Peninsula of Michigan. Twenty-seven of 93 bird species hosted ticks with an overall prevalence (=at least one tick) of 3.6% (185/5,122). Median burden was one tick/per infested bird with a range of 1-16 ticks per infested bird. Tick species collected were primarily Haemaphysalis leporispalustris (Packard) and Ixodes scapularis Say, with …

Multi-Year Biological Control Of Black Vine Weevil, Otiorhynchus Sulcatus, With Persistent Entomopathogenic Nematodes, Elson J. Shields, Antonio M. Testa

The Great Lakes Entomologist

Abstract:

The black vine weevil (BVW), Otiorhynchus sulcatus Fabricius (Coleoptera: Curculionidae), has a worldwide distribution and is a serious pest of many agricultural crops with a host plant species range of 140 plants. Common economic losses occur in small fruits, including strawberries, ornamental and nursery plants, caused primarily by the root feeding larvae resulting in reduced vigor and plant death.

The susceptibility of BVW to entomopathogenic nematodes (EPNs) is well established with numerous authors publishing papers using a wide array of EPN species from commercial sources and very high application rates for use as a biopesticide. The concept of using …

Minnesota State Records For Osmia Georgica, Megachile Inimica, And Megachile Frugalis (Hymenoptera, Megachilidae), Including A New Nest Description For Megachile Frugalis Compared With Other Species In The Subgenus Sayapis, Colleen D. Satyshur, Thea A. Evans, Britt M. Forsberg, Robert B. Blair

The Great Lakes Entomologist

In this note, we report the first Minnesota state records of Osmia (Helicosmia) georgica Cresson 1878,Megachile (Sayapis) inimica Cresson 1872, and Megachile (Sayapis) frugalis Cresson 1872, which were collected in 2018. We also provide the first description of the nest structure of M. frugalis. All three species typically have more southern distributions. The nest of M. frugalis shows similar structure to other species in the subgenus Sayapis Titus, such as M. inimica and M. pugnata, particularly in that the longitudinal nest cell walls lack a lining of leaf pieces, and the cell partitions are made from …

A Synopsis Of The Flat Bugs (Heteroptera: Aradidae) Of Michigan, Daniel R. Swanson

The Great Lakes Entomologist

An overview of the 28 species of Aradidae found in Michigan is presented, along with an identification key, distribution maps, and relevant literature. Eleven new state records are presented for the following species: Aradus approximatus Parshley, Aradus duzeei Bergroth, Aradus falleni Stål, Aradus insolitus Van Duzee, Aradus intectus Parshley, Aradus montanus Bergroth, Aradus proboscideus Walker, Aradus shermani Heidemann, Aradus uniformis Heidemann, Quilnus niger (Stål) (all Aradinae), and Neuroctenus simplex (Uhler) (Mezirinae).

Cover Pages For Tgle Vol. 53 Nos. 3 & 4

The Great Lakes Entomologist

Cover Pages for TGLE Vol. 53 Nos. 3 & 4

Resources And Resilience In Older Women: Implications For Health Outcomes And Culturally Tailored Interventions., Sparkle Springfield Phd

Faculty & Staff Black History Research Symposium

Dr. Springfield's Bio:

As a nutritionist, Springfield’s research interests focus on the social, behavioral, and structural determinants of dietary behaviors in African American women and developing community-based interventions to promote health equity. Her most recent work examines relationships between psychological resilience, diet quality, and cardiovascular disease-related outcomes.

Abstract: 

Introduction 

Resilience – which we define as the “ability to bounce back from stress” – can foster successful aging among older, ethnically diverse women. This study investigated the association between psychological resilience in the Women’s Health Initiative Extension Study (WHI-ES) and three constructs defined by Staudinger’s 2015 model of resilience and aging: …

Bookpourri: Reviews Of Books For K-5 Children, Vera E. Milz

Michigan Reading Journal

No abstract provided.

Learning To Use Reciprocal Teaching: One Teacher's Journey, Ann Hager

Michigan Reading Journal

No abstract provided.

Observational Study Of Two Ex Situ North American River Otters (Lontra Canadensis), Julia Rifenberg

The Pegasus Review: UCF Undergraduate Research Journal

Zoos enable the ability to study how captive conditions impact the behaviors of animals. In this study, I observed two North American river otters housed at the Central Florida Zoo to evaluate behavioral changes after the male had been removed from the female for a month-long medical examination. The aim of this study was to 1) determine if mating behaviors were still occurring between the two river otters following the male’s removal and 2) to assess the welfare of the male and female river otters in captivity by observing their interactions and individual behaviors. Observed behaviors were compared to documented …

Manuscripts: Preservation In The Digital Age, Sarita Somarajan, S Mohamed Esmail Dr

Library Philosophy and Practice (e-journal)

Library is the indispensable part of educational institution designed to serve educational, cultural, research, recreational information to the users. . Libraries are the places wherever the complete information gathering takes place together with intellectual and our cultural heritage. The collections possessed by the library are affected by numerous environmental factors that ultimately results in irreparable harm to numerous collections. The information embodied in manuscripts is effective however materials used for this purpose cause a true challenge. These manuscripts have proof of facts, their accomplishments, thoughts, work they need done, theories then on, that are essential for human development. These guide …

Reaction Coordinate And Thermodynamics Of Base Flipping In Rna, Lev Levintov, Sanjib Paul, Harish Vashisth

New Hampshire EPSCoR

Base flipping is a key biophysical event involved in recognition of various ligands by ribonucleic acid (RNA) molecules. However, the mechanism of base flipping in RNA remains poorly understood, in part due to the lack of atomistic details on complex rearrangements in neighboring bases. In this work, we applied transition path sampling (TPS) methods to study base flipping in a double-stranded RNA (dsRNA) molecule that is known to interact with RNA-editing enzymes through this mechanism. We obtained an ensemble of 1000 transition trajectories to describe the base-flipping process. We used the likelihood maximization method to determine the refined reaction coordinate …

2020 Annual Report, Prep (Piscataqua Region Estuaries Partnership)

PREP Reports & Publications

No abstract provided.

Commonwealth Times 2021-02-17

Commonwealth Times, 1969-

No abstract provided.

The Pedagogical Representation Of Mass Functions With Lego And Their Origin, Stefan Kautsch

Chemistry and Physics Faculty Articles

We promote the teaching of mass functions as an integral part of an interdisciplinary science education. Mass functions characterize the frequency distributions of objects with different masses on all cosmic scales. We intend to enhance experiential learning of this concept with a creative LEGO brick experiment for a diverse student audience. To our surprise, the LEGO mass function is not only qualitatively but also quantitatively comparable to mass functions found across the universe. We also discuss the relation between gravitation and mass distributions as a possible explanation for the continuity of the universal mass function.

Neuro-Anatomical Changes Of Carbon Monoxide Poisoning On Advanced Imaging: A Literature Review, James M. Mckivigan, Gregory Gilmour

Touro Scholarly Works

Carbon monoxide (CO) poisoning is a major public health issue in the United States that accounts for approximately 50% of poisoning cases in the nation each year and around 50,000 emergency room visits. In most instances of CO poisoning, the culprit is a malfunctioning or poorly tended heating system within the home or, occasionally, commercial building, which causes the system to leak this hazardous gas. One of the more insidious aspects of CO poisoning is that the gas is odorless and colorless, and victims of CO poisoning often do not realize that there is a problem until they begin to …

The Need For Dedicated Microbiology Leadership In The Clinical Microbiology Laboratory, Linoj P. Samuel, Glen T. Hansen, Colleen S. Kraft, Bobbi S. Pritt

Pathology and Laboratory Medicine Articles

Clinical microbiology laboratories play a crucial role in patient care using traditional and innovative diagnostics. Challenges faced by laboratories include emerging pathogens, rapidly evolving technologies, healthcare-acquired infections, antibiotic-resistant organisms and diverse patient populations. Despite these challenges, many clinical microbiology laboratories in the United States are not directed by doctoral level microbiology-trained individuals with sufficient time dedicated to laboratory leadership. This manuscript highlights the need for medical microbiology laboratory directors with appropriate training and qualifications.

Uab Biology Professor Awarded Nsf Early Concept Grant For Exploratory Research, Staff

Browse All News

No abstract provided.

Role Of Nadþ In Regulating Cellular And Metabolic Signaling Pathways, Sara Amjad, Sabah Nisar, Ajaz A. Bhat, Ab Rauf Shah, Michael P. Frenneaux, Khalid Fakhro, Mohammad Haris, Ravinder Reddy, Zoltan Patay, Joseph Baur, Puneet Bagga

Department of Agricultural and Biological Systems Engineering: Faculty Publications

Background: Nicotinamide adenine dinucleotide (NAD⁺), a critical coenzyme present in every living cell, is involved in a myriad of metabolic processes associated with cellular bioenergetics. For this reason, NAD⁺ is often studied in the context of aging, cancer, and neurodegenerative and metabolic disorders.

Scope of review: Cellular NAD⁺ depletion is associated with compromised adaptive cellular stress responses, impaired neuronal plasticity, impaired DNA repair, and cellular senescence. Increasing evidence has shown the efficacy of boosting NAD⁺ levels using NAD⁺ precursors in various diseases. This review provides a comprehensive understanding into the role of NAD^{+ …}

Using Molecular Dynamics Simulations To Understand Receptor-Complex Communication And Signaling, Hannah Margaret Hoag

Theses and Dissertations

The overarching purpose of this document is to use Computer-aided drug design and Molecular dynamic simulations to better understand elusive drug-receptor interactions, as well as various types of inter-receptor signaling. Chapter One introduces the theory and importance of Computer-aided drug design and the methodology used in both Chapters Two and Three.

Chapter Two uncovers the relationship between the well-studied ABCB1 transporter and a newly identified drug known as Xanthohumol (XN). XN is compared to a commonly used drug, Doxorubicin (DOX), in this chapter. If the ABCB1 transporter can be properly inhibited, cancer-fighting drugs will be able to stay within the …

Pharmacokinetic And Pharmacodynamic Profiling Of Minocycline For Injection Following A Single Infusion In Critically Ill Adults In A Phase Iv Open-Label Multicenter Study (Acumin), Thomas P Lodise, Yasir Hamad, Et Al

Open Access Publications

Intravenous (i.v.) minocycline is increasingly used to treat infections caused by multidrug-resistant (MDR)

February 17, 2021, Faculty, Illinois Wesleyan University

2020-2021

No abstract provided.

CertL Reduces C16 Ceramide, Amyloid-Β Levels, And Inflammation In A Model Of Alzheimer’S Disease, Simone M. Crivelli, Qian Luo, Jo A. A. Stevens, Caterina Giovagnoni, Daan Van Kruining, Gerard Bode, Sandra Den Hoedt, Barbara Hobo, Anna-Lena Scheithauer, Jochen Walter, Monique T. Mulder, Christopher Exley, Matthew Mold, Michelle M. Mielke, Helga E. De Vries, Kristiaan Wouters, Daniel L. A. Van Den Hove, Dusan Berkes, María Dolores Ledesma, Joost Verhaagen, Mario Losen, Erhard Bieberich, Pilar Martinez-Martinez

Physiology Faculty Publications

BACKGROUND: Dysregulation of ceramide and sphingomyelin levels have been suggested to contribute to the pathogenesis of Alzheimer's disease (AD). Ceramide transfer proteins (CERTs) are ceramide carriers which are crucial for ceramide and sphingomyelin balance in cells. Extracellular forms of CERTs co-localize with amyloid-β (Aβ) plaques in AD brains. To date, the significance of these observations for the pathophysiology of AD remains uncertain.

METHODS: A plasmid expressing CERT_L, the long isoform of CERTs, was used to study the interaction of CERT_L with amyloid precursor protein (APP) by co-immunoprecipitation and immunofluorescence in HEK cells. The recombinant CERT_L protein …

Balancing Trade And Economic Security: Andritz V. United States And The Role Of Customs And Border Protection In Enforcing The Plant Protection Act, Alexandra Khrebtukova

University of Miami International and Comparative Law Review

This paper examines the case of Andritz v. United States—first filed in the U.S. Court of International Trade then transferred to the U.S. District Court for the Southern District of Texas—as a demonstrative case study highlighting the collaboration between U.S. Customs and Border Protection (CBP) of the Department of Homeland Security and the Animal and Plant Health Inspection Service (APHIS) of the Department of Agriculture. CBP is charged with facilitating legitimate trade and travel while safeguarding the borders of the United States to protect against, inter alia, the entry of dangerous goods, including through agricultural import and entry inspection. …

Retiform Hemangioendothelioma: A Case Series And Review Of The Literature, Qurratulain Chundriger, Muhammad Usman Tariq, Shabina Rahim, Jamshid Abdul-Ghafar, Nasir Ud Din

Department of Pathology and Laboratory Medicine

Background: Retiform Hemangioendothelioma (RH) is an extremely rare vascular tumor of intermediate biological behavior, which is prone to local recurrence but rarely shows metastasis to distant sites. It may harbor areas resembling Dabska tumor in some cases and angiosarcoma, which in its well differentiated form may exhibit similar pathological appearance in some areas, making it problematic to rule out a possibility of a malignant diagnosis on a core biopsy. Therefore, complete surgical resection with negative margins is essential for accurate diagnosis and local control.
Results: In our series, two of the three Pakistani cases were in females, with an age …

Mapping Major Sars-Cov-2 Drug Targets And Assessment Of Druggability Using Computational Fragment Screening: Identification Of An Allosteric Small-Molecule Binding Site On The Nsp13 Helicase., Matthew R Freidel, Roger S Armen

College of Pharmacy Faculty Papers

The 2019 emergence of, SARS-CoV-2 has tragically taken an immense toll on human life and far reaching impacts on society. There is a need to identify effective antivirals with diverse mechanisms of action in order to accelerate preclinical development. This study focused on five of the most established drug target proteins for direct acting small molecule antivirals: Nsp5 Main Protease, Nsp12 RNA-dependent RNA polymerase, Nsp13 Helicase, Nsp16 2'-O methyltransferase and the S2 subunit of the Spike protein. A workflow of solvent mapping and free energy calculations was used to identify and characterize favorable small-molecule binding sites for an aromatic pharmacophore …

Missing The Marc: Utilization Of Marc Fields In The Search Process, Liz Woolcott, Andrea Payant, Becky Skeen, Paul Daybell

Library Faculty & Staff Publications

Utah State University Cataloging and Metadata Services (CMS) unit analyzed MARC record discoverability within the libraries’ discovery layer, Encore, using web analytics, a web-scrapping tool, and a relational database to examine MARC records listed in users’ search results. MARC records were identified, isolated, and coded to pinpoint where search terms appeared, determine whether they were present in full or in part, and ascertain prominent fields not present in records. Analysis of results showed that notes and summaries were important for record retrieval and that users interacted with authorized name fields more frequently than authorized subject fields.

The Mitochondrial Protease Lonp1 Promotes Proteasome Inhibitor Resistance In Multiple Myeloma, Polina Iakova, Shannon E Moree, Ergun Sahin, Premal Lulla, Sarvari V Yellapragada, Francis T F Tsai, Andre Catic

Faculty, Staff and Students Publications

Multiple myeloma and its precursor plasma cell dyscrasias affect 3% of the elderly population in the US. Proteasome inhibitors are an essential part of several standard drug combinations used to treat this incurable cancer. These drugs interfere with the main pathway of protein degradation and lead to the accumulation of damaged proteins inside cells. Despite promising initial responses, multiple myeloma cells eventually become drug resistant in most patients. The biology behind relapsed/refractory multiple myeloma is complex and poorly understood. Several studies provide evidence that in addition to the proteasome, mitochondrial proteases can also contribute to protein quality control outside of …

Nvp-Bez235 Or Jaki Treatment Leads To Decreased Survival Of Examined Gbm And Bbc Cells, Neftali Vazquez, Alma Lopez, Victoria Cuello, Michael W. Persans, Erin Schuenzel, Wendy Innis-Whitehouse, Megan Keniry

School of Integrative Biological & Chemical Sciences (Formerly Dept. of Biology)

Cancer cells almost universally harbor constitutively active Phosphatidylinositol-3 Kinase (PI3K) Pathway ac-tivity via mutation of key signaling components and/or epigenetic mechanisms. Scores of PI3K Pathway in-hibitors are currently under investigation as putative chemotherapeutics. However, feedback and stem cell mechanisms induced by PI3K Pathway inhibition can lead to reduced treatment efficacy. To address therapeutic barriers, we examined whether JAKi would reduce stem gene expression in a setting of PI3K Pathway inhibition in order to improve treatment efficacy. We targeted the PI3K Pathway with NVP-BEZ235 (dual PI3K and mTOR inhibitor) in combination with the Janus Kinase inhibitor JAKi in glioblastoma (GBM) and …