Digital Commons Network^™

Mortality Comparison Of Using Anti Interleukin-6 Therapy And Using Standard Treatment In Severe Covid-19, Jonathan Christianto Sutadji, Agung Dwi Wahyu Widodo, Danti Nur Indiastuti

Folia Medica Indonesiana

Severe Coronavirus Disease 19 (COVID-19) can cause serious lung inflammation and death. COVID-19 is characterized by a high mortality rate. This severity is associated with the overproduction of proinflammatory cytokines called "cytokine storms". One of the cytokines that play a central role is Interleukin-6 (IL-6). High IL-6 levels are associated with mortality. Expectedly, the IL-6 blockade could reduce cytokine storms and thus reduce deaths in severe COVID-19 patients. This systematic review aimed to summarize the comparison between mortality using anti-IL-6 therapy and mortality using standard treatment in severe COVID-19 patients. We systematically searched the PubMed, ScienceDirect, and ProQuest databases until …

A Group Of Homoeopathic Medicines For Covid-19: A Systematic Review Of Clinical Features, Horacio Escalante, Nazmul Hasan, Adriana Delgado, Salvador Soto, Jessica Vivas

Indian Journal of Research in Homoeopathy

Background: Historically, several homoeopathic medicines are known to have attributed a significant role in the control and management of infectious epidemic diseases. Objectives: This study aimed to compile a list of prospective homoeopathic medicines for the treatment and prophylaxis of the COVID-19 epidemic by conducting a systematic review and statistical analysis of clinical characteristics of this emerging coronavirus disease. Materials and Methods: A> systematic review protocol was developed according to the reporting items of the Preferred Reporting Items for Systematic Reviews and Meta-Analyses statement. Articles for review were selected from PubMed, World Health Organization database, MedRxiV, and BioRxiv. Studies in …

American Punishment And Pandemic, Danielle C. Jefferis

Nevada Law Journal

Many of the sites of the worst outbreaks of the disease caused by the novel coronavirus (COVID-19) are America’s prisons and jails. As of March 2021, the virus has infected hundreds of thousands of incarcerated people and well over two thousand have died as a result contracting the disease caused by the virus. Prisons and jails have been on perpetual lockdowns since the onset of the pandemic, with family visits suspended and some facilities resorting to solitary confinement to mitigate the virus’s spread, thereby exacerbating the punitiveness and harmfulness of incarceration. With the majority of the 2.3 million people incarcerated …

The Improvement Of Community Knowledge, Attitudes And Practices After Covid-19 Socialization, Siti Khaerunnisa, Irmi Syafa'ah, Citrawati Dyah Kencono Wungu, Gwenny Ichsan Prabowo, Retno Handajani, Indri Safitri, Harianto Notopuro, Ema Qurnianingsih, Lina Lukitasari, Ira Humairah, Arief Bakhtiar, Suwandito Suwandito, Susi Wahyuning Asih, Zuhrotul Eka Yulis Anggraeni, Ginanjar Sasmito Adi, Ely Rahmatika Nugrahani, Ayesie Natasha Zulka, Soetjipto Soetjipto

Folia Medica Indonesiana

This study determined community knowledge, attitudes, and practices after COVID-19 socialization in Rambipuji and Suci Village, Jember District, East Java, Indonesia. This study used the analytic observational design study. As many as 40 people were given socialization about COVID-19 by gathering and online. The questionnaires were completed in two parts included before-socialization and after-socialization. The questionnaire data were analyzed descriptively by calculating frequency, percentage, and inferential statistics by t-test, Spearman correlation, and chi-square test. The data analysis used IBM SPSS version 23 software. The mean and standard deviation of percentage of knowledge pre-test, knowledge post-test, high attitude, moderate attitude, low …

Molecular Genotyping Of Tsst-1 Gene Staphylococcus Aureus From Clinical Specimen, Marinda Dwi Puspitarini, Wahyu Setyarini, Usman Hadi, Kuntaman Kuntaman

Folia Medica Indonesiana

Staphylococcus aureus (S. aureus) is the most common pathogen in humans that causes various infections. Variations in infections due to S. aureus are related to the presence of virulence factors, one of which is Toxic Shock Syndrome Toxin-1 (TSST-1) which is the main cause of Toxic Shock Syndrome (TSS). This study aimed to explore the genetic pattern of the tsst-1 genes among MSSA and MRSA from clinical isolates of patients at Dr. Soetomo Academic Hospital, Surabaya-Indonesia. PCR examination was performed on 106 clinical samples of S. aureus isolates to determine the presence of the tsst-1 genes; subsequently, phylogenetic analysis was …

Distribution Of Human Papilloma Virus (Hpv) In Cervical Adenocarcinoma And Adenosquamous Carcinoma, Gondo Mastutik, Alphania Rahniayu, Nila Kurniasari, Anny Setijo Rahaju, Budi Harjanto

Folia Medica Indonesiana

Approximately 20-30% of all cervical cancer cases are adenocarcinoma and adenosquamous carcinoma. Around 70% of all of these types of cancer are related to infection of Human Papillomavirus (HPV). This study evaluated the distribution of HPV genotype in cervical adenocarcinoma and adenosquamous carcinoma. A cross-sectional study was conducted at the Department of Anatomic Pathology, Dr. Soetomo General Academic Hospital, Surabaya, Indonesia, from January to December 2015. The sample were 22 formalin-fixed paraffin-embedded (FFPE) of cervical adenocarcinoma tissues and adenosquamous carcinoma tissues. FFPE was used for DNA extraction and followed with HPV genotyping to detect 40 genotypes of HPV, including low …

Overview Of The Microbiome Among Nurses Study (Micro-N) As An Example Of Prospective Characterization Of The Microbiome Within Cohort Studies, Christine Everett, Chengchen Li, Jeremy E. Wilkinson, Long H. Nguyen, Lauren J. Mciver, Kerry Ivey, Jacques Izard, Natalia Palacios, A. Heather Eliassen, Walter C. Willett, Alberto Ascherio, Qi Sun, Shelley S. Tworoger, Andrew T. Chan, Wendy S. Garrett, Curtis Huttenhower, Eric B. Rimm, Mingyang Song

Department of Food Science and Technology: Faculty Publications

A lack of prospective studies has been a major barrier for assessing the role of the microbiome in human health and disease on a population-wide scale. To address this significant knowledge gap, we have launched a large-scale collection targeting fecal and oral microbiome specimens from 20,000 women within the Nurses’ Health Study II cohort (the Microbiome Among Nurses study, or Micro-N). Leveraging the rich epidemiologic data that have been repeatedly collected from this cohort since 1989; the established biorepository of archived blood, urine, buccal cell, and tumor tissue specimens; the available genetic and biomarker data; the cohort’s ongoing follow-up; and …

An Evaluation Of Body-Grip Trap Trigger Configurations For Reducing River Otter Take Incidental To Beaver Trapping, Alec J. Sundelius, Nicholas Forman, Nathan M. Roberts, Shawn T. Rossler, David B. Ruid, Robert C. Willging

United States Department of Agriculture Wildlife Services: Staff Publications

River otter (Lontra canadensis) populations in North America have been the focus of significant restoration efforts. Wildlife management agencies, concerned about the unintentional take of river otters incidental to beaver (Castor canadensis) trapping, may recommend techniques to avoid capturing river otters. River otter avoidance techniques that are ineffective or diminish trap performance for beavers are undesirable. We conducted a field evaluation in 2015 and 2016 in Wisconsin to assess how two trigger configurations (offset and center) on body-grip traps would affect the incidental capture rate of river otters during beaver trapping. We also evaluated effects of …

Outpatient Antibiotic Handbook, Children's Mercy Kansas City

Clinical Pathways (Formally Known As Care Process Models)

No abstract provided.

Covid-19: A Crisis And An Opportunity To Improve The Emergency Use Authorization Process, Daniel Walsh

Minnesota Journal of Law, Science & Technology

No abstract provided.

Modeling The Spread Of Covid-19 Over Varied Contact Networks, Ryan L. Solorzano

Master's Theses

When attempting to mitigate the spread of an epidemic without the use of a vaccine, many measures may be made to dampen the spread of the disease such as physically distancing and wearing masks. The implementation of an effective test and quarantine strategy on a population has the potential to make a large impact on the spread of the disease as well. Testing and quarantining strategies become difficult when a portion of the population are asymptomatic spreaders of the disease. Additionally, a study has shown that randomly testing a portion of a population for asymptomatic individuals makes a small impact …

N Y State Dent J June-July 2021

The New York State Dental Journal

The New York State Dental Journal (NYSDJ) is produced by the New York State Dental Association (NYSDA) six times a year, in January, March, April, July, September and November. Each issue features clinical and scientific articles written by researchers and practitioners from around the globe and is subject to review by a panel of specialists convened by the Editor.

Issues include cover and feature articles alongside regular columns with regional news impacting the New York membership including editorial and perspectives columns, legal, association activities, component news, continuing education opportunities, and classifieds.

Impact Of Intratumor Heterogeneity And The Tumor Microenvironment In Shaping Tumor Evolution And Response To Therapy, Akash Mitra

Dissertations and Theses (Open Access)

Intratumor heterogeneity (ITH) is a crucial challenge in cancer treatment. The genotypic and phenotypic heterogeneity underlying diverse cancer types leads to subclonal variation, which may result in mixed or failed response to therapy. The heterogeneity at the tumor level, along with the tumor microenvironment (TME), often shapes tumor evolution and ultimately clinical outcome. Given that modern treatment paradigms increasingly expose patients with metastatic disease to multiple treatment modalities through the course of their disease, there exists a need to characterize robust and predictive biomarkers of response to therapy. In order to accurately characterize tumor evolution, we need to account for …

Hypoxia Acts As An Environmental Cue For The Human Tissue-Resident Memory T-Cell Differentiation Program, Farah Hasan

Dissertations and Theses (Open Access)

Tissue-resident memory T-cells (T_RM) provide frontline defense against viral diseases and can contribute to anti-tumor immunity; however, aside from the necessity of TGF-β, little is known regarding cues for T_RM differentiation. Oxygen tension is an environmental cue that distinguishes peripheral tissues from the circulation and here, we demonstrate that differentiation of human CD8+ T-cells under hypoxic conditions in the presence of TGF-β1 led to the development of a T_RM phenotype, characterized by a greater than five-fold increase in CD69+CD103+ cells expressing human T_RM hallmarks and enrichment for endogenous human T_RM gene signatures, including increased …

An Assessment Of Outpatient Clinic Room Ventilation Systems And Possible Relationship To Disease Transmission, Kristin G King, George L Delclos, Eric L Brown, Susan Tortolero Emery, Jose Miguel Yamal, Robert J Emery

Faculty, Staff and Student Publications

BACKGROUND: With healthcare shifting to the outpatient setting, this study examined whether outpatient clinics operating in business occupancy settings were conducting procedures in rooms with ventilation rates above, at, or below thresholds defined in the American National Standards Institute/American Society of Heating, Refrigerating and Air-Conditioning Engineers/American Society for Health Care Engineering Standard 170 for Ventilation in Health Care Facilities and whether lower ventilation rates and building characteristics increase the risk of disease transmission.

METHODS: Ventilation rates were measured in 105 outpatient clinic rooms categorized by services rendered. Building characteristics were evaluated as determinants of ventilation rates, and risk of disease …

Divide And Conquer: A Hygienic, Efficient, And Reliable Assembly-Line For Housekeeping, Xiao Alison Chen, Rowan Wang, Jianghua Zhang

Research Collection Lee Kong Chian School Of Business

Problem definition: This work focuses on the hotel housekeeping process. In a field study, a possible channel of disease transmission between consecutive guests in hotel rooms is revealed. In order to prevent the transmission, an innovative assembly-line housekeeping method is developed. Academic/practical relevance: The transmission of infectious diseases during hotel stays (e.g., by touching unclean towels or bed linens) has been reported globally. Under the current COVID-19 pandemic, having contact with saliva or mucus left by an infected person could cause infection. The standard housekeeping process used by the majority of hotels leaves a channel for new towels and bed …

Community Healthcare Clinic - Adaptation System To The Pandemic And Post Pandemic Periods, Nhu Le

Masters Theses

Due to COVID-19, uncertainties and significant changes have been occurring around the world, especially in the U.S. The future is always ambiguous but it will lead to breakthroughs. Emerging issues are the vulnerability of previous conventional design solutions, especially of the healthcare-related architecture and urban planning.

This thesis focuses on helping construct a new healthcare system, which could be used during either a pandemic or post-pandemic era, by designing a local community clinic. In fact, public health clinics are always needed and expected to be more flexibly adjustable and up-gradable. Those new clinics play a very important role since the …

Manahatta, Nicholas Hinckfuss

Masters Theses

The explosive population growth of overly indulgent urban societies, in conjunction with the absence of systematic structures that alleviate human environmental impacts, contribute to unfavorable socio-economic consequences which actively interfere with the long-term prospect of human development. One of the hidden costs of the urban population boom is the alarming trend of infectious disease outbreaks. To meet the demands of an ever growing population, essential urban conditions such as green spaces, eco-infrastructure, and amiable living conditions are lacking from modern urban contexts. New York City, is the perfect example of a hyperly urban community that lacks an overall organizational strategy …

Incidence Of Intestinal Parasitic Infections Among Random Samples At Al- Aziziyah Hospital In Wasit Province/Iraq, Zeina Anwar Jaffar, Ashwak Jasim Kzar Shammari, Maysoon Abdul-Zahra Merdaw

Baghdad Science Journal

The study is designed to identify intestinal parasitic infections examined at Al-Aziziyah Hospital in Wasit Governorate in Iraq. In this study, a total of (460) internal and external patients were monitored for intestinal parasitic infections. All stool samples were analyzed by the direct method (microscopic exam.) to discover the trophozoite stages and cyst stages for intestinal protozoan parasites. The most incidence parasites in different sex, area residence and different age groups. Out of (460) patient sample were infected with 217 at a percentage of (47.17%), 101(46.5%) were for males and 116 (53.5%) were for females. It was found that the …

Cured: Proposing A Solution To The Hague Convention’S “Zone Of Disease” Defense, Savannah Mora

Chicago Journal of International Law

Each year, thousands of children are taken from their homes to foreign countries by one of their parents (the “taking parent”) without the consent of their other parent (the “left-behind parent”). This phenomenon is frequently referred to as international child abduction. If both the country from which the child was taken and the country to which the child was taken are signatories to the Hague Convention, the left-behind parent can file a petition for return of the child under the treaty. Recently, in a number of courts around the world, taking parents facing Hague Convention litigation have argued that, because …

A Comparison Of Intestinal Parasite Infections And Activity Budgets In Three Free-Ranging Vs. Enclosure-Housed Lemur Species (Lemur Catta, Varecia Rubra, And Eulemur Mongoz), Angela M. Achorn, Jeffrey Winking

Anthropology Faculty Publications

This study examines how range size affects intestinal parasite infections, and how such infections affect activity budgets in captive lemurs. There were no differences in parasite richness or intensity attributable to habitat type. However, there was a strong suggestion that parasite loads reduce activity levels.

Toxoplasma Gondii, Suicidal Behavior, And Intermediate Phenotypes For Suicidal Behavior, Teodor T. Postolache, Abhishek Wadhawan, Dan Rujescu, Andrew J. Hoisington, Aline Dagdag, Enrique Baca-Garcia, Christopher A. Lowry, Olaoluwa O. Okusaga, Lisa A. Brenner

Faculty Publications

Within the general literature on infections and suicidal behavior, studies on Toxoplasma gondii ( T. gondii ) occupy a central position. This is related to the parasite's neurotropism, high prevalence of chronic infection, as well as specific and non-specific behavioral alterations in rodents that lead to increased risk taking, which are recapitulated in humans by T. gondii's associations with suicidal behavior, as well as trait impulsivity and aggression, mental illness and traffic accidents. This paper is a detailed review of the associations between T. gondii serology and suicidal behavior, a field of study that started 15 years ago with our …

A Case Study On The Ucsf Transplant Center Renovation: Mitigating Covid-19 Risks And Tracking Cost Impact, Alec Steven Woodyatt

Construction Management

At the beginning of 2020, the world was turned upside down at the hands of the global coronavirus pandemic. Today, economies and business are counting the costs and wondering what recovery will look like – how to navigate and adapt to a new style of life after returning from government-mandated lockdowns. The question on everyone’s minds is, “how do we continue to work while keeping people safe?” This question is extremely relevant in the construction industry where, for most people, working from home is not an option. This case study will delve into how Dome Construction, along with their client, …

Prevalence And Outcome Of Isoniazid-Monoresistant Tuberculosis At A University Hospital In Saudi Arabia, Khalifa M. Binkhamis, Mohammed A. Bahatheg, Faisal A. Altahan, Saleh S. Alwakeel, Khalid A. Almutairi, Abdullah F. Alsaeed, Dalal A. Alkadi, Hanan A. Alshafai, Fahad M. Almajid, Mazin A. Barry

Saudi Medical Journal

Objectives: To determine the prevalence and outcome in patients with isoniazid-monoresistant Mycobacterium tuberculosis complex and compare them to those in patients with non-isoniazid-monoresistant Mycobacterium tuberculosis . Methods: This cross-sectional analytical study was conducted at King Khalid University Hospital, Riyadh, Saudi Arabia. The data were retrospectively collected from the electronic medical records of patients who tested positive for Mycobacterium tuberculosis between May 2015 and April 2019. Results: We identified 105 patients infected with Mycobacterium tuberculosis . The prevalence proportion of isoniazid-monoresistant tuberculosis was 8.6% (n=9). Five patients with isoniazid-monoresistant tuberculosis (55.6%) were successfully treated, while one patient died. In the nonresistant …

Trade Administration, Kathleen Claussen

Articles

At the core of public debates about trade policy making in the United States and the so-called "trade war" is a controversy over who should be responsible for making U.S. trade law: Congress or the President. What these important conversations miss is that underlying much of our trade policy in recent decades is a widespread executive-branch lawmaking apparatus with monitoring, rulemaking, adjudicative, and enforcement features that operates in considerable shadow. Executive branch agencies are now the primary actors in trade lawmaking. This Article excavates that critical underbelly: what I call our "trade administrative state." It maps the trade administrative state's …

Experience And Satisfaction With Hearing Aid Services Delivered Via Teleaudiology In Adult Populations: A Systematic Review, Shelby Platia

Dissertations, Theses, and Capstone Projects

Objective: The goal of this systematic review is to examine the current literature to look at patient experience and satisfaction with teleaudiology services. Specifically, teleaudiology services that occur at the fitting and/or post-fitting stage of the adult hearing aid patient journey.

Methods: A comprehensive search utilizing PubMed, MEDLINE and EBSCOhost databases were conducted to identify pertinent, peer-reviewed, articles related to the clinical usage or clinical applications of teleaudiology for hearing aid fittings and/or follow-up for adult individuals. Inclusion criteria were studies that are empirical, included quantitative results, articles published in English, peer-reviewed articles; and persons who are 18 …

Global Research Trends And Network Visualization On Climate Action : A Bibliometric Study, Binod K. Das, Mayuri Pandya, Shanti P. Chaudhari, Atul Bhatt, Dharmendra Trivedi

Library Philosophy and Practice (e-journal)

Abstract

The purpose of the study is to explore the bibliometric features of scientific publications in the area of climate action for the period during 1995–2020, thus, enabling the scientific community to understand the research progress on the topic. The data of the scientific publications were retrieved from the Scopus database. The key word “Climate Action” were applied as topic terms to search articles published during the study period. Total 1638 scientific publications retrieved for statistical analysis for bibliometric analysis and for visualization network analysis study has VOSviewer© tools along with RStudio and MS Excel. Result shows steady progress on …

Dean's Update, June 2021, Jerry Nadler

SOM Dean's Research Newsletter

No abstract provided.

Cortical Screw Fixation Using Ct-Navigation Coupled With Real-Time Electrophysiological Monitoring Of Individual Screw Placement For Unstable Degenerative Lumbar Spondylolisthesis, Fiu Herbert Wertheim College Of Medicine Affiliates, Kunal Patel, Daniel Segui, Amy Starosciak, Sergio Gonzalez-Arias

All Publications

No abstract provided.

The Covid-19 Pandemic And International Law, Preston J. Lim, Oona A. Hathaway, Alasdair Phillips-Robins, Mark Stevens

Faculty Publications

How does the COVID-19 pandemic affect States’ obligations under international law? This is a question of not just academic interest but real importance for people’s lives. After all, whether States abide by international law—and whether international law is fit for purpose—is vitally important for everyone from refugees exposed to the virus in unsanitary detention centers to national leaders fighting disinformation campaigns and safeguarding vaccine supply chains. International law has been central to the world’s response to the pandemic from the start—even if the participants did not always realize it. International law, after all, required States to take certain actions to …