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2021

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Pase Perdido Missing Pass, Larissa M. Garcia Jan 2021

Pase Perdido Missing Pass, Larissa M. Garcia

Theses and Dissertations

This paper contains the following terms: colonialism, ghost populations, natural occurrences, global positioning, poetic relation, confrontation/vengeance, mapping, graphs, models, warfare, bio warfare, magic, mystery, migration, memory, mutation, ghosts, and esoteric systems


Medical Expenditures And Health Care Utilization: A Comparison Among U.S. Adult Tobacco Consumers (I.E. Never Tobacco Users, Cigarette Smokers And Smokeless Tobacco Users), Raheema S. Muhammad Jan 2021

Medical Expenditures And Health Care Utilization: A Comparison Among U.S. Adult Tobacco Consumers (I.E. Never Tobacco Users, Cigarette Smokers And Smokeless Tobacco Users), Raheema S. Muhammad

Theses and Dissertations

Introduction

Cigarette smoking poses a great economic cost on the U.S. health care system by incurring high health care expenditure and health care utilization in the adult population. Although there is a sufficient amount of information on the health care cost associated with cigarette smoking there is a gap in how other forms of tobacco use may impact healthcare expenditures and utilization in comparison to cigarette smoking. The main objectives of this study were: 1) to estimate and compare health care expenditure and health care utilization across different tobacco use groups using nationally representative data 2) to estimate and compare …


Governance ≠ Leadership: What Blockchain And Ai Won't Do For Corporate Lawyers, Jeffrey M. Lipshaw Jan 2021

Governance ≠ Leadership: What Blockchain And Ai Won't Do For Corporate Lawyers, Jeffrey M. Lipshaw

Suffolk University Law School Faculty Works

This is a contribution to the Journal of Corporation Law’s 2020 symposium on blockchain technology and corporate governance. The thesis is that blockchain technology is well suited to the monitoring function in corporate governance; that monitoring as the primary function of corporate governance is a particularly legal conception; and that the business conception of governance has far more to do with leadership, strategy, and operations. If the legal and business conceptions of governance tend to be ships passing in the night (at least in this somewhat exaggerated rendering), it is because prevailing economic and legal theoretical models have a difficult …


The Role Of Social Media In Human Trafficking Victimization, Alicia Marie Terwilliger Jan 2021

The Role Of Social Media In Human Trafficking Victimization, Alicia Marie Terwilliger

Theses and Dissertations

Human trafficking is the recruitment, transportation, transfer, harboring, and receipt of people. Humans are one of the only global commodities that can be sold and used repeatedly (Jones et al., 2007), helping to make trafficking a multi-billion-dollar industry worldwide. There are several types of trafficking, including forced labor, debt bondage, organ harvesting, and sexual exploitation. Often, trafficking includes threats, the use of force, coercion, abduction, and fraud for exploitation, labor, harvested organs, or sex. Human trafficking occurs domestically and across international borders, with over 45 million victims globally (Bonilla & Mo, 2019). Every state in the United States is affected …


Vol. 24, No. 2: Full Issue, Water Law Review Jan 2021

Vol. 24, No. 2: Full Issue, Water Law Review

Water Law Review

No abstract provided.


The Aboriginal Land And Water Rights Of The Jemez Pueblo, John W. Ragsdale Jr. Jan 2021

The Aboriginal Land And Water Rights Of The Jemez Pueblo, John W. Ragsdale Jr.

Water Law Review

No abstract provided.


Sub-Optimal Deterrence And Criminal Sanctioning Under The U.S. Clean Water Act, Joshua Ozymy, Melissa Jarrell Ozymy Jan 2021

Sub-Optimal Deterrence And Criminal Sanctioning Under The U.S. Clean Water Act, Joshua Ozymy, Melissa Jarrell Ozymy

Water Law Review

Both the U.S. Environmental Protection Agency ("EPA") and Department of Justice put forth significant resources to investigate and prosecute environmental crimes under the U.S. Clean Water Act ("CWA"). Criminal sanctions are used to raise the cost of violations relative to the benefits of criminal action to directly deter rational individuals and firms from offending and indirectly via the observation of other potential offenders. While many studies examine sanctioning in environmental law, little research explores the plausibility of any deterrent effects of criminal sanctions under the CWA. We use content analysis to explore all criminal prosecutions resulting from EPA criminal investigations, …


Covid-19 Student Mental Health Check, Dianna Blankenship, Irma S. Jones Jan 2021

Covid-19 Student Mental Health Check, Dianna Blankenship, Irma S. Jones

Criminal Justice Faculty Publications

The COVID-19 pandemic has produced many changes in the lives of our students and families. In this article, the responses of students in criminal justice classes at a Hispanic serving institution in south Texas were collected and synthesized. The 252 responses were divided into seven frequently observed and repeated themes: jobs and job related, school and courses, graduation, routine, family, positivity, and groceries/shopping. Findings for this time period matched what much of what the national and international news and reports have all reported. It indicates that, as teaching professionals, we must be mindful to provide the added support to assist …


The Second World Ocean Assessment Volume 1, Jason Hall-Spencer, Louise Firth Jan 2021

The Second World Ocean Assessment Volume 1, Jason Hall-Spencer, Louise Firth

School of Biological and Marine Sciences

In its resolutions 57/141 and 58/240, the General Assembly decided to establish a regular processunder the United Nations for global reporting and assessment of the state of the marineenvironment, including socioeconomic aspects, both current and foreseeable, building on existingregional assessments. In its resolution 71/257, the Assembly recalled that the scope of thefirst cycle of the Regular Process focused on establishing a baseline and decided that the scopeof the second cycle would extend to evaluating trends and identifying gaps. The programme ofwork for the period 2017–2020 of the second cycle of the Regular Process includes the preparationby the Group of Experts …


Through A Lens Of Therapeutic Jurisprudence: A Case Study Of The Children’S Court Drug Court In Perth, Suzanne Ellis Jan 2021

Through A Lens Of Therapeutic Jurisprudence: A Case Study Of The Children’S Court Drug Court In Perth, Suzanne Ellis

Theses: Doctorates and Masters

The Children’s Court Drug Court (CCDC) has operated for 20 years in Perth as an alternative Court for drug-using young offenders who present at the Children’s Court. Despite the CCDC’s relative longevity, researchers have examined neither the inner workings of the Court nor the experiences of its actors. The current study aimed, not to evaluate the CCDC, but to identify measures needed to refine CCDC processes to enhance the experiences and outcomes of young people who participate in the CCDC. It argues that despite the CCDC’s foundations in contentious therapeutic jurisprudence principles, on balance, the actors – young people, their …


Evaluating The Relative Importance Of Stormwater For Nutrient And Metal Contamination To The Urban, Groundwater Dependent Yellagonga Wetlands, Through Wetland Budgeting, Jonas Polifka Jan 2021

Evaluating The Relative Importance Of Stormwater For Nutrient And Metal Contamination To The Urban, Groundwater Dependent Yellagonga Wetlands, Through Wetland Budgeting, Jonas Polifka

Theses: Doctorates and Masters

Wetlands provide numerous ecosystem services and can be utilised as pollutant sinks, however excessive contamination of wetlands can induce adverse effects to wetland ecology and lead to degradation of its values. Runoff from precipitation mobilizes contaminants from impervious surfaces which are, in some case, transported directly to wetlands through stormwater drainage. Urban stormwater can be a significant source of contaminants to wetlands, although its overall importance needs to be assessed for each wetland individually. Wetland budgeting is a management tool used to evaluate the relative importance of contaminant sources to wetlands, by comparing contaminant loads. Environmental management of the Yellagonga …


Coalition For Prisoners' Rights Newsletter, Vol. 46-C, No. 2, Coalition For Prisoners' Rights Jan 2021

Coalition For Prisoners' Rights Newsletter, Vol. 46-C, No. 2, Coalition For Prisoners' Rights

Coalition for Prisoners' Rights Newsletters

Is It Life or Death?

Behind Bars

No Sense

Free Newsletter

The Least Read Part of the Newsletter

"La Colina Escalamos"

Resources & Information


The Health Of Older Western Australians: The Role Of Age, Gender, Geographic Location, Psychological Distress, Perceived Health, Tobacco And Alcohol, Celia Wilkinson, Kim Clarke, Ros Sambell, Julie Dare, Stephen J. Bright Jan 2021

The Health Of Older Western Australians: The Role Of Age, Gender, Geographic Location, Psychological Distress, Perceived Health, Tobacco And Alcohol, Celia Wilkinson, Kim Clarke, Ros Sambell, Julie Dare, Stephen J. Bright

Research outputs 2014 to 2021

Purpose: Rates of drinking- and alcohol-related harms among older adults are increasing in most developed nations. The purpose of this paper was to explore the relationship among at-risk alcohol use, smoking, gender, geographical location, self-reported health and psychological well-being among Western Australians aged 65 years and older.

Design/methodology/approach: A secondary analysis was conducted of a cross-sectional survey that collected data from 7,804 West Australians aged 65 years and older between 2013 and 2015. Participants were categorised according to the following age groups: young-old (aged 65–74 years), older-old (aged 75–84 years) and oldest-old (aged 85+ years).

Findings: Results from a multinomial …


Evaluation Of The Antimicrobial Activity Of Ridinilazole And Six Comparators Against Chinese, Japanese And South Korean Strains Of Clostridioides Difficile, Deirdre A. Collins, Yuan Wu, Kazuhiro Tateda, Hee Jung Kim, Richard J. Vickers, Thomas V. Riley Jan 2021

Evaluation Of The Antimicrobial Activity Of Ridinilazole And Six Comparators Against Chinese, Japanese And South Korean Strains Of Clostridioides Difficile, Deirdre A. Collins, Yuan Wu, Kazuhiro Tateda, Hee Jung Kim, Richard J. Vickers, Thomas V. Riley

Research outputs 2014 to 2021

BACKGROUND: Clostridioides difficile is the most common cause of antimicrobial-associated diarrhoea in high-income countries. Fluoroquinolone resistance enabled the emergence and intercontinental spread of the epidemic ribotype (RT) 027 strain of C. difficile in the early 2000s. Despite frequent inappropriate antimicrobial use in Asia, RT 027 is rarely isolated in the region, but the often fluoroquinolone- and clindamycin-resistant RT 017 strain predominates. OBJECTIVES: This study evaluated the antimicrobial activity of ridinilazole, a novel antimicrobial agent with highly specific activity for C. difficile, against clinical strains of C. difficile from Asia. METHODS: C. difficile strains from Japan (n = 64), South Korea …


Accountability’S Aa1000ap Standard: A Framework For Integrating Sustainability Into Organisations, Muhammad Bilal Farooq, Rashid Zaman, Muhammad Nadeem Jan 2021

Accountability’S Aa1000ap Standard: A Framework For Integrating Sustainability Into Organisations, Muhammad Bilal Farooq, Rashid Zaman, Muhammad Nadeem

Research outputs 2014 to 2021

Purpose: This study aims to evaluate corporate sustainability integration by evaluating corporate practices against the sustainability principles of inclusivity, materiality, responsiveness and impact outlined in AccountAbility’s AA1000 Accountability Principles (AA1000AP) standard.

Design/methodology/approach: Data comprise 12 semi-structured interviews with senior managers of listed New Zealand companies. Findings are evaluated against AccountAbility’s principles of inclusivity, materiality, responsiveness and impact, which are based on a normative view of stakeholder theory.

Findings: In terms of inclusivity, stakeholder engagement is primarily monologic and is directed more towards traditional stakeholder groups. However, social media, which is gaining popularity, has the potential to facilitate greater dialogic stakeholder …


Are National Cancer Control Indicators For Patient Experiences Being Met In Regional And Remote Australia? A Cross-Sectional Study Of Cancer Survivors Who Travelled For Treatment, Jeff Dunn, Belinda Goodwin, Joanne F. Aitken, Sonja March, Fiona Crawford-Williams, Michael Ireland, Nicholas Ralph, Leah Zajdlewicz, Arlen Rowe, Suzanne K. Chambers Jan 2021

Are National Cancer Control Indicators For Patient Experiences Being Met In Regional And Remote Australia? A Cross-Sectional Study Of Cancer Survivors Who Travelled For Treatment, Jeff Dunn, Belinda Goodwin, Joanne F. Aitken, Sonja March, Fiona Crawford-Williams, Michael Ireland, Nicholas Ralph, Leah Zajdlewicz, Arlen Rowe, Suzanne K. Chambers

Research outputs 2014 to 2021

Objective: To examine the health services experience of patients with cancer from regional and remote Australia using the Australian National Cancer Control Indicators (NCCI) guidelines as an assessment framework. Design: Cross-sectional. Setting Queensland non-for-profit cancer accommodation lodges. Participants: Participants were patients with cancer who travelled for treatment from rural and remote Queensland to major urban centres (n=518; age mean=64.6, SD=11.18). Outcome measures: Assessments included NCCI patient indicators, quality of life (QoL), psychological distress and unmet supportive care needs. Results: The frequency at which NCCI indicators were met ranged from 37.5% for receiving an assessment and care plan to 97.3% for …


How Is Organisational Fit Addressed In Australian Entry Level Midwifery Job Advertisements, Dianne Bloxsome, Courtney Glass, Sara Bayes Jan 2021

How Is Organisational Fit Addressed In Australian Entry Level Midwifery Job Advertisements, Dianne Bloxsome, Courtney Glass, Sara Bayes

Research outputs 2014 to 2021

Background: Midwifery job retention is an ongoing global issue. Prior research has recognised that considering an individual’s attributes in relation to their work environment may assist in improving job satisfaction among midwives, leading to improved long-term job retention in the midwifery profession. The aim of this study was to evaluate whether, and how organisational fit is addressed in current entry level midwifery job advertisements within Australia. Methods: Midwifery jobs were searched for within 12 search engines, using the search term ‘midwife’, including Seek.com, Indeed.com, government employment websites for all Australian states and territories, and private health organisation websites. Data were …


Process Development And Safety Evaluation Of Abcb5+ Limbal Stem Cells As Advanced-Therapy Medicinal Product To Treat Limbal Stem Cell Deficiency, Alexandra Norrick, Jasmina Esterlechner, Elke Niebergall-Roth, Ulf Dehio, Samar Sadeghi, Hannes M. Schröder, Seda Ballikaya, Nicole Stemler, Christoph Ganss, Kathrin Dieter, Ann-Kathrin Dachtler, Patrick Merz, Saadettin Sel, James Chodosh, Claus Cursiefen, Natasha Y. Frank, Gerd U. Auffarth, Bruce Ksander, Markus H. Frank, Mark A. Kluth Jan 2021

Process Development And Safety Evaluation Of Abcb5+ Limbal Stem Cells As Advanced-Therapy Medicinal Product To Treat Limbal Stem Cell Deficiency, Alexandra Norrick, Jasmina Esterlechner, Elke Niebergall-Roth, Ulf Dehio, Samar Sadeghi, Hannes M. Schröder, Seda Ballikaya, Nicole Stemler, Christoph Ganss, Kathrin Dieter, Ann-Kathrin Dachtler, Patrick Merz, Saadettin Sel, James Chodosh, Claus Cursiefen, Natasha Y. Frank, Gerd U. Auffarth, Bruce Ksander, Markus H. Frank, Mark A. Kluth

Research outputs 2014 to 2021

Background: While therapeutic success of the limbal tissue or cell transplantation to treat severe cases of limbal stem cell (LSC) deficiency (LSCD) strongly depends on the percentage of LSCs within the transplanted cells, prospective LSC enrichment has been hampered by the intranuclear localization of the previously reported LSC marker p63. The recent identification of the ATP-binding cassette transporter ABCB5 as a plasma membrane-spanning marker of LSCs that are capable of restoring the cornea and the development of an antibody directed against an extracellular loop of the ABCB5 molecule stimulated us to develop a novel treatment strategy based on the utilization …


An Integrative Literature Review Of The Implementation Of Microcredentials In Higher Education: Implications For Practice In Australasia, Ratna M. Selvaratnam, Michael D. Sankey Jan 2021

An Integrative Literature Review Of The Implementation Of Microcredentials In Higher Education: Implications For Practice In Australasia, Ratna M. Selvaratnam, Michael D. Sankey

Research outputs 2014 to 2021

Micro-credentials research, which includes digital badges, is a relatively new field of study that seeks to inform the implementation, portability and sustainability of the ecology of meaningful delivery. This paper reviews literature relevant to understanding connections between universities' intent to offer micro-credentials and the environment that is needed to do so. From this integrated study, the paper distils a number of core concerns and identifies some gaps in the literature. One of its primary goals is to clear the ground for the construction of a technical model of micro-credentialing implementation that can be used by the various stakeholders involved in …


Standardisation Of Clinical Assessment, Management And Follow-Up Of Acute Hospitalised Exacerbation Of Copd: A Europe-Wide Consensus, Sanjay Ramakrishnan, Wim Janssens, Pierre R. Burgel, Marco Contoli, Frits M. E. Franssen, Neil J. Greening, Timm Greulich, Iwein Gyselinck, Andreas Halner, Arturo Huerta, Rebecca L. Morgan, Jennifer K. Quint, Lowie E. G. W. Vanfleteren, Kristina Vermeersch, Henrik Watz, Mona Bafadhel Jan 2021

Standardisation Of Clinical Assessment, Management And Follow-Up Of Acute Hospitalised Exacerbation Of Copd: A Europe-Wide Consensus, Sanjay Ramakrishnan, Wim Janssens, Pierre R. Burgel, Marco Contoli, Frits M. E. Franssen, Neil J. Greening, Timm Greulich, Iwein Gyselinck, Andreas Halner, Arturo Huerta, Rebecca L. Morgan, Jennifer K. Quint, Lowie E. G. W. Vanfleteren, Kristina Vermeersch, Henrik Watz, Mona Bafadhel

Research outputs 2014 to 2021

Background: Despite hospitalization for exacerbation being a high-risk event for morbidity and mortality, there is little consensus globally regarding the assessment and management of hospitalised exacerbations of COPD. We aimed to establish a consensus list of symptoms, physiological measures, clinical scores, patient questionnaires and investigations to be obtained at time of hospitalised COPD exacerbation and follow-up. Methods: A modified Delphi online survey with pre-defined consensus of importance, feasibility and frequency of measures at hospitalisation and follow-up of a COPD exacerbation was undertaken. Findings: A total of 25 COPD experts from 18 countries contributed to all 3 rounds of the survey. …


Development Of A Breech-Specific Integrated Care Pathway For Pregnant Women: Protocol For A Mixed Methods Study, Sara Morris, Sadie Geraghty, Deborah Sundin Jan 2021

Development Of A Breech-Specific Integrated Care Pathway For Pregnant Women: Protocol For A Mixed Methods Study, Sara Morris, Sadie Geraghty, Deborah Sundin

Research outputs 2014 to 2021

Background: The development of an integrated care pathway with multidisciplinary input to standardize and streamline care for pregnant women experiencing breech presentation at 36 or more weeks of gestation poses several challenges because of the divisive and contentious nature of the phenomenon. Although many clinicians are interested in obtaining the skills required to safely support women desiring a vaginal breech birth, the primary trend in most health care facilities is to recommend a cesarean section. Objective: This paper aims to discuss the mixed methods approach used in a doctoral study conducted to generate new knowledge regarding women’s experiences of breech …


Detect Schools Study Protocol: A Prospective Observational Cohort Surveillance Study Investigating The Impact Of Covid-19 In Western Australian Schools, Marianne J. Mullane, Hannah M. Thomas, Melanie Epstein, Joelie Mandzufas, Narelle Mullan, Alexandra Whelan, Karen Lombardi, Tina Barrow, Sherlynn Ang, Adele Leahy, Ewan Cameron, Leanne Lester, Matt Cooper, Paul Stevenson, Mitch Hartman, Anne Mckenzie, Francis Mitrou, Stephen R. Zubrick, Juli Coffin, Donna Cross, Asha C. Bowen, Peter Gething Jan 2021

Detect Schools Study Protocol: A Prospective Observational Cohort Surveillance Study Investigating The Impact Of Covid-19 In Western Australian Schools, Marianne J. Mullane, Hannah M. Thomas, Melanie Epstein, Joelie Mandzufas, Narelle Mullan, Alexandra Whelan, Karen Lombardi, Tina Barrow, Sherlynn Ang, Adele Leahy, Ewan Cameron, Leanne Lester, Matt Cooper, Paul Stevenson, Mitch Hartman, Anne Mckenzie, Francis Mitrou, Stephen R. Zubrick, Juli Coffin, Donna Cross, Asha C. Bowen, Peter Gething

Research outputs 2014 to 2021

Introduction: Amidst the evolving COVID-19 pandemic, understanding the transmission dynamics of the SARS-CoV-2 virus is key to providing peace of mind for the community and informing policy-making decisions. While available data suggest that school-aged children are not significant spreaders of SARS-CoV-2, the possibility of transmission in schools remains an ongoing concern, especially among an aging teaching workforce. Even in low-prevalence settings, communities must balance the potential risk of transmission with the need for students' ongoing education. Through the roll out of high-throughput school-based SARS-CoV-2 testing, enhanced follow-up for individuals exposed to COVID-19 and wellbeing surveys, this study investigates the dynamics …


A Geospatiotemporal And Causal Inference Epidemiological Exploration Of Substance And Cannabinoid Exposure As Drivers Of Rising Us Pediatric Cancer Rates, Albert S. Reece, Gary K. Hulse Jan 2021

A Geospatiotemporal And Causal Inference Epidemiological Exploration Of Substance And Cannabinoid Exposure As Drivers Of Rising Us Pediatric Cancer Rates, Albert S. Reece, Gary K. Hulse

Research outputs 2014 to 2021

Background: Age-adjusted US total pediatric cancer incidence rates (TPCIR) rose 49% 1975–2015 for unknown reasons. Prenatal cannabis exposure has been linked with several pediatric cancers which together comprise the majority of pediatric cancer types. We investigated whether cannabis use was related spatiotemporally and causally to TPCIR. Methods: State-based age-adjusted TPCIR data was taken from the CDC Surveillance, Epidemiology and End Results cancer database 2003–2017. Drug exposure was taken from the nationally-representative National Survey of Drug Use and Health, response rate 74.1%. Drugs included were: tobacco, alcohol, cannabis, opioid analgesics and cocaine. This was supplemented by cannabinoid concentration data from the …


Plasma Amyloid‐Beta Levels In A Pre‐Symptomatic Dutch‐Type Hereditary Cerebral Amyloid Angiopathy Pedigree: A Cross‐Sectional And Longitudinal Investigation, Pratishtha Chatterjee, Michelle Tegg, Steve Pedrini, Anne M. Fagan, Chengjie Xiong, Abhay K. Singh, Kevin Taddei, Samantha Gardener, Colin L. Masters, Peter R. Schofield, Gerhard Multhaup, Tammie L. S. Benzinger, John C. Morris, Randall J. Bateman, Steven M. Greenberg, Mark A. Van Buchem, Erik Stoops, Hugo Vanderstichele, Charlotte E. Teunissen, Graeme J. Hankey, Marieke J. H. Wermer, Hamid R. Sohrabi, Ralph N. Martins, The Dominantly Inherited Alzheimer Network Jan 2021

Plasma Amyloid‐Beta Levels In A Pre‐Symptomatic Dutch‐Type Hereditary Cerebral Amyloid Angiopathy Pedigree: A Cross‐Sectional And Longitudinal Investigation, Pratishtha Chatterjee, Michelle Tegg, Steve Pedrini, Anne M. Fagan, Chengjie Xiong, Abhay K. Singh, Kevin Taddei, Samantha Gardener, Colin L. Masters, Peter R. Schofield, Gerhard Multhaup, Tammie L. S. Benzinger, John C. Morris, Randall J. Bateman, Steven M. Greenberg, Mark A. Van Buchem, Erik Stoops, Hugo Vanderstichele, Charlotte E. Teunissen, Graeme J. Hankey, Marieke J. H. Wermer, Hamid R. Sohrabi, Ralph N. Martins, The Dominantly Inherited Alzheimer Network

Research outputs 2014 to 2021

Plasma amyloid‐beta (Aβ) has long been investigated as a blood biomarker candidate for Cerebral Amyloid Angiopathy (CAA), however previous findings have been inconsistent which could be attributed to the use of less sensitive assays. This study investigates plasma Aβ alterations between pre‐symptomatic Dutch‐type hereditary CAA (D‐CAA) mutation‐carriers (MC) and non-carriers (NC) using two Aβ measurement platforms. Seventeen pre‐symptomatic members of a D‐ CAA pedigree were assembled and followed up 3–4 years later (NC = 8;MC = 9). Plasma Aβ1‐40 and Aβ1‐42 were cross‐sectionally and longitudinally analysed at baseline (T1) and follow‐up (T2) and were found to be lower in MCs …


Metabolomics And Lipidomics: Expanding The Molecular Landscape Of Exercise Biology, Mehdi R. Belhaj, Nathan G. Lawler, Nolan J. Hoffman Jan 2021

Metabolomics And Lipidomics: Expanding The Molecular Landscape Of Exercise Biology, Mehdi R. Belhaj, Nathan G. Lawler, Nolan J. Hoffman

Research outputs 2014 to 2021

Dynamic changes in circulating and tissue metabolites and lipids occur in response to exercise-induced cellular and whole-body energy demands to maintain metabolic homeostasis. The metabolome and lipidome in a given biological system provides a molecular snapshot of these rapid and complex metabolic perturbations. The application of metabolomics and lipidomics to map the metabolic responses to an acute bout of aerobic/endurance or resistance exercise has dramatically expanded over the past decade thanks to major analytical advancements, with most exercise-related studies to date focused on analyzing human biofluids and tissues. Experimental and analytical con-siderations, as well as complementary studies using animal model …


High Commitment Hrm And Burnout Of Frontline Food Service Employees: A Moderated Mediation Model, Stephen T. Teo, Diep T. N. Nguyen, Azadeh Shafaei, Tim Bentley Jan 2021

High Commitment Hrm And Burnout Of Frontline Food Service Employees: A Moderated Mediation Model, Stephen T. Teo, Diep T. N. Nguyen, Azadeh Shafaei, Tim Bentley

Research outputs 2014 to 2021

Purpose:

Drawing from the Job Demands-Resources (JD-R) framework and Conservation of Resources (COR) theory, the authors’ study examines the impact of high commitment HR management (HCHRM) practices and psychological capital (PsyCap) on job autonomy and job demands in predicting burnout in frontline food service employees.

Design/methodology/approach:

A moderated mediation model was developed and tested on 257 Australian workers employed in the food service industry. Hypotheses were tested using structural equation modeling.

Findings:

There was support for the mediation effect of HCHRM on burnout, via two sequential mediators: job autonomy and job demands. PsyCap was found to buffer (moderation) the effect …


Hospital Staff, Volunteers’ And Patients’ Perceptions Of Barriers And Facilitators To Communication Following Stroke In An Acute And A Rehabilitation Private Hospital Ward: A Qualitative Description Study, Sarah D'Souza, Erin Godecke, Natalie Ciccone, Deborah J. Hersh, Heidi Janssen, Elizabeth Armstrong Jan 2021

Hospital Staff, Volunteers’ And Patients’ Perceptions Of Barriers And Facilitators To Communication Following Stroke In An Acute And A Rehabilitation Private Hospital Ward: A Qualitative Description Study, Sarah D'Souza, Erin Godecke, Natalie Ciccone, Deborah J. Hersh, Heidi Janssen, Elizabeth Armstrong

Research outputs 2014 to 2021

Objectives

To explore barriers and facilitators to patient communication in an acute and rehabilitation ward setting from the perspectives of hospital staff, volunteers and patients following stroke.

Design

A qualitative descriptive study as part of a larger study which aimed to develop and test a Communication Enhanced Environment model in an acute and a rehabilitation ward.

Setting

A metropolitan Australian private hospital.

Participants

Focus groups with acute and rehabilitation doctors, nurses, allied health staff and volunteers (n=51), and interviews with patients following stroke (n=7), including three with aphasia, were conducted.

Results

The key themes related to barriers and facilitators to …


Meta-Analysis Of Genome-Wide Dna Methylation Identifies Shared Associations Across Neurodegenerative Disorders, Marta F. Nabais, Simon M. Laws, Tian Lin, Costanza L. Vallerga, Nicola J. Armstrong, Ian P. Blair, John B. Kwok, Karen A. Mather, George D. Mellick, Perminder S. Sachdev, Leanne Wallace, Anjali K. Henders, Ramona A. J. Zwamborn, Paul J. Hop, Katie Lunnon, Ehsan Pishva, Janou A. Y. Roubroeks, Hilkka Soininen, Magda Tsolaki, Patrizia Mecocci, Simon Lovestone, Iwona Kłoszewska, Bruno Vellas, Sarah Furlong, Fleur C. Garton, Robert D. Henderson, Susan Mathers, Pamela A. Mccombe, Merrilee Needham, Shyuan T. Ngo, Garth Nicholson, Roger Pamphlett, Dominic B. Rowe, Frederik J. Steyn, Kelly L. Williams, Tim J. Anderson, Steven R. Bentley, John Dalrymple-Alford, Javed Fowder, Jacob Gratten, Glenda Halliday, Ian B. Hickie, Martin Kennedy, Simon J. G. Lewis, Grant W. Montgomery, John Pearson, Toni L. Pitcher, Peter Silburn, Futao Zhang, Peter M. Visscher, Jian Yang, Anna J. Stevenson, Robert F. Hillary, Riccardo E. Marioni, Sarah E. Harris, Ian J. Deary, Ashley R. Jones, Aleksey Shatunov, Alfredo Iacoangeli, Wouter Van Rheenen, Leonard H. Van Den Berg, Pamela J. Shaw, Cristopher E. Shaw, Karen E. Morrison, Ammar Al-Chalabi, Jan H. Veldink, Eilis Hannon, Jonathan Mill, Naomi R. Wray, Allan F. Mcrae, The Alzheimer's Disease Neuroimaging Initiative, The Australian Imaging Biomarkers And Lifestyle Study Jan 2021

Meta-Analysis Of Genome-Wide Dna Methylation Identifies Shared Associations Across Neurodegenerative Disorders, Marta F. Nabais, Simon M. Laws, Tian Lin, Costanza L. Vallerga, Nicola J. Armstrong, Ian P. Blair, John B. Kwok, Karen A. Mather, George D. Mellick, Perminder S. Sachdev, Leanne Wallace, Anjali K. Henders, Ramona A. J. Zwamborn, Paul J. Hop, Katie Lunnon, Ehsan Pishva, Janou A. Y. Roubroeks, Hilkka Soininen, Magda Tsolaki, Patrizia Mecocci, Simon Lovestone, Iwona Kłoszewska, Bruno Vellas, Sarah Furlong, Fleur C. Garton, Robert D. Henderson, Susan Mathers, Pamela A. Mccombe, Merrilee Needham, Shyuan T. Ngo, Garth Nicholson, Roger Pamphlett, Dominic B. Rowe, Frederik J. Steyn, Kelly L. Williams, Tim J. Anderson, Steven R. Bentley, John Dalrymple-Alford, Javed Fowder, Jacob Gratten, Glenda Halliday, Ian B. Hickie, Martin Kennedy, Simon J. G. Lewis, Grant W. Montgomery, John Pearson, Toni L. Pitcher, Peter Silburn, Futao Zhang, Peter M. Visscher, Jian Yang, Anna J. Stevenson, Robert F. Hillary, Riccardo E. Marioni, Sarah E. Harris, Ian J. Deary, Ashley R. Jones, Aleksey Shatunov, Alfredo Iacoangeli, Wouter Van Rheenen, Leonard H. Van Den Berg, Pamela J. Shaw, Cristopher E. Shaw, Karen E. Morrison, Ammar Al-Chalabi, Jan H. Veldink, Eilis Hannon, Jonathan Mill, Naomi R. Wray, Allan F. Mcrae, The Alzheimer's Disease Neuroimaging Initiative, The Australian Imaging Biomarkers And Lifestyle Study

Research outputs 2014 to 2021

Background: People with neurodegenerative disorders show diverse clinical syndromes, genetic heterogeneity, and distinct brain pathological changes, but studies report overlap between these features. DNA methylation (DNAm) provides a way to explore this overlap and heterogeneity as it is determined by the combined effects of genetic variation and the environment. In this study, we aim to identify shared blood DNAm differences between controls and people with Alzheimer’s disease, amyotrophic lateral sclerosis, and Parkinson’s disease. Results: We use a mixed-linear model method (MOMENT) that accounts for the effect of (un)known confounders, to test for the association of each DNAm site with each …


Circulating Tumor Dna Reflects Uveal Melanoma Responses To Protein Kinase C Inhibition, John J. Park, Russell J. Diefenbach, Natalie Byrne, Georgina V. Long, Richard A. Scolyer, Elin S. Gray, Matteo S. Carlino, Helen Rizos Jan 2021

Circulating Tumor Dna Reflects Uveal Melanoma Responses To Protein Kinase C Inhibition, John J. Park, Russell J. Diefenbach, Natalie Byrne, Georgina V. Long, Richard A. Scolyer, Elin S. Gray, Matteo S. Carlino, Helen Rizos

Research outputs 2014 to 2021

The prognosis for patients with UM is poor, and recent clinical trials have failed to prolong overall survival (OS) of these patients. Over 95% of UM harbor activating driver mutations, and this allows for the investigation of ctDNA. In this study, we investigated the value of ctDNA for adaptive clinical trial design in metastatic UM. Longitudinal plasma samples were analyzed for ctDNA in 17 metastatic UM patients treated with PKCi-based therapy in a phase 1 clinical trial setting. Plasma ctDNA was assessed using digital droplet PCR (ddPCR) and a custom melanoma gene panel for targeted next generation sequencing (NGS). Baseline …


Classification Of Skin Disease Using Deep Learning Neural Networks With Mobilenet V2 And Lstm, Parvathaneni N. Srinivasu, Jalluri G. Siva Sai, Muhammad F. Ijaz, Akash K. Bhoi, Wonjoon Kim, James J. Kang Jan 2021

Classification Of Skin Disease Using Deep Learning Neural Networks With Mobilenet V2 And Lstm, Parvathaneni N. Srinivasu, Jalluri G. Siva Sai, Muhammad F. Ijaz, Akash K. Bhoi, Wonjoon Kim, James J. Kang

Research outputs 2014 to 2021

Deep learning models are efficient in learning the features that assist in understanding complex patterns precisely. This study proposed a computerized process of classifying skin disease through deep learning-based MobileNet V2 and Long Short Term Memory (LSTM). The MobileNet V2 model proved to be efficient with a better accuracy that can work on lightweight computational devices. The proposed model is efficient in maintaining stateful information for precise predictions. A grey-level co-occurrence matrix is used for assessing the progress of diseased growth. The performance has been compared against other state-of-the-art models such as Fine-Tuned Neural Networks (FTNN), Convolutional Neural Network (CNN), …