Digital Commons Network^™

Assessment Of The Impact Of Tardive Dyskinesia In Clinical Practice: Consensus Panel Recommendations, Richard Jackson, Matthew N Brams, Leslie Citrome, Amber R Hoberg, Stuart H Isaacson, John M Kane, Rajeev Kumar

Faculty, Staff and Students Publications

PURPOSE: Tardive dyskinesia (TD) is a hyperkinetic movement disorder in which patients experience abnormal involuntary movements that can have profound negative impacts on physical, cognitive, and psychosocial functioning. Use of measures to assess the functional impact of TD in routine clinical practice is lacking. To address this gap, an advisory panel of experts in psychiatry and movement disorder neurology was convened to develop consensus recommendations on assessment of the impact of TD on patients' functioning that can be used in clinical practice.

METHODS: An advisory panel provided recommendations using an iterative process, beginning with a narrative literature review regarding current …

X-Linked Serotonin 2c Receptor Is Associated With A Non-Canonical Pathway For Sudden Unexpected Death In Epilepsy, Cory A Massey, Samantha J Thompson, Ryan W Ostrom, Janice Drabek, Olafur A Sveinsson, Torbjörn Tomson, Elisabeth A Haas, Othon J Mena, Alica M Goldman, Jeffrey L Noebels

Faculty, Staff and Students Publications

Sudden Unexpected Death in Epilepsy is a leading cause of epilepsy-related mortality, and the analysis of mouse Sudden Unexpected Death in Epilepsy models is steadily revealing a spectrum of inherited risk phenotypes based on distinct genetic mechanisms. Serotonin (5-HT) signalling enhances post-ictal cardiorespiratory drive and, when elevated in the brain, reduces death following evoked audiogenic brainstem seizures in inbred mouse models. However, no gene in this pathway has yet been linked to a spontaneous epilepsy phenotype, the defining criterion of Sudden Unexpected Death in Epilepsy. Most monogenic models of Sudden Unexpected Death in Epilepsy invoke a failure of inhibitory synaptic …

Examination Of Sex- And Limb-Specific Fatigue During Unilateral, Isometric Forearm Exercise, Caleb Christian Voskuil

Theses and Dissertations--Kinesiology and Health Promotion

The purpose of this study was to examine the effects of unilateral, isometric handgrip holds to failure for the dominant (Dm) and non-dominant (NDm) limb on ipsilateral ([IPS] exercised side) and contralateral ([CON] non-exercised side) performance fatigability. Twenty individuals participated in this study (Men [n =10]; Women [n = 10; Composite Demographics: Age: 22.2 years; Height: 174.4 cm; Body Mass: 75.0 kg) and completed three visits. Two, 6 s maximal voluntary isometric contractions (MVICs) for the Dm and NDm limb were performed during visit 1, followed by a familiarization of the fatigue test. Visits 2 and 3 included an isometric, …

Quantification Of In-Play Competition Demands Of Collegiate American Football Players Using Global Positioning Systems, Alex Brownell

Theses and Dissertations--Kinesiology and Health Promotion

There is limited information describing the competition demands of American football. A greater understanding of competition demands will allow strength and conditioning practitioners to create appropriate training programs to enhance athlete readiness and performance. Therefore, the purpose of this study was to analyze the competition demands of collegiate American football players using global positioning systems (GPS), specifically comparing the in-play GPS versus out-of-play GPS outcomes. Twenty-two American football athletes (Age: 20.8 ± 0.9 yr, Height: 190.2 ± 4.7 cm, Body mass: 113.4 ± 22.3 kg) were monitored during 12 regular season competitions over 13 weeks. Athletes were divided into specific …

Drivers Of Health Policy Adoption: A Political Economy Of Hiv Treatment Policy, Matthew M. Kavanagh, Kalind Parish, Somya Gupta

Georgetown Law Faculty Publications and Other Works

Why do some countries rapidly adopt policies suggested by scientific consensus while others are slow to do so? Through a mixed methods study, we show that the institutional political economy of countries is a stronger and more robust predictor of health policy adoption than either disease burden or national wealth. Our findings challenge expectations in scholarship and among many international actors that policy divergence is best addressed through greater evidence and dissemination channels. Our study of HIV treatment policies shows that factors such as the formal structures of government and the degree of racial and ethnic stratification in society predict …

Federal Courts: Art. Iii(1), Art. I(8), Art. Iv(3)(2), Art. Ii(2)/I(8)(3), And Art. Ii(1) Adjudication, Laura K. Donohue, Jeremy M. Mccabe

Georgetown Law Faculty Publications and Other Works

The distinction among the several types of federal courts in the United States has gone almost unremarked in the academic literature. Instead, attention focuses on Article III “constitutional” courts with occasional discussion of how they differ from what are referred to as “non-constitutional” or “legislative” courts. At best, these labels are misleading: all federal courts have a constitutional locus, and most, but not all, federal courts are brought into being via legislation. The binary approach further ignores the full range of federal courts, which are rooted in different constitutional provisions: Art. III(1), Art. I(8); Art. IV(3); Art. II(2)/I(8)(3); and Art. …

The Evolution And Jurisprudence Of The Foreign Intelligence Surveillance Court And Foreign Intelligence Surveillance Court Of Review, Laura K. Donohue

Georgetown Law Faculty Publications and Other Works

The past eight years have witnessed an explosion in the number of publicly-available opinions and orders issued by the Foreign Intelligence Surveillance Court and Foreign Intelligence Surveillance Court of Review. From only six opinions in the public domain 1978–2012, by early 2021, eighty-eight opinions had been released. The sharp departure is even more pronounced in relation to orders: from only one order declassified during 1978–2012, since 2013, 288 have been formally released. These documents highlight how the courts’s roles have evolved since 2004 and reveal four key areas that dominate the courts’ jurisprudence: its position as a specialized, Article III …

Sovereignty 2.0, Anupam Chander, Haochen Sun

Georgetown Law Faculty Publications and Other Works

Digital sovereignty—the exercise of control over the internet—is the ambition of the world’s leaders, from Australia to Zimbabwe, a bulwark against both foreign state and foreign corporation. Governments have resoundingly answered first-generation internet law questions of who if anyone should regulate the internet—they all will. We now confront second generation questions—not whether, but how to regulate the internet. We argue that digital sovereignty is simultaneously a necessary incident of democratic governance and democracy’s dreaded antagonist. As international law scholar Louis Henkin taught us, sovereignty can insulate a government’s worst ills from foreign intrusion. Assertions of digital sovereignty, in particular, …

Board Gender Diversity: A Path To Achieving Substantive Equality In The United States, Kimberly A. Houser, Jamillah Bowman Williams

Georgetown Law Faculty Publications and Other Works

While the European Union (EU) was founded on the concept of equality as a fundamental value in 1993, the United States was created at a time when women were considered legally inferior to men. This has had the lasting effect of preventing women in the United States from making inroads into positions of power. While legislated board gender diversity (BGD) mandates have been instituted in some EU countries, the United States has been loath to take that route, relying instead on the goodwill of corporate boards, with little progress. On September 30, 2018, however, California enacted a law that has …

Could Private Legislation Be The First Key To Unlocking The Nation’S Information Resources In The Battle Against Misinformation?, Michelle M. Wu

Georgetown Law Faculty Publications and Other Works

Unfiltered, unverified information flows freely on the web and is much more easily found and used than reliable sources. There are logical reasons for this, as quality, reliable information often costs both time and money to investigate, verify, and publish. However, that type of investment only justifies the charging for the information at the outset, not the cabining of it once it is available and has been purchased. Where public libraries have acquired content, they should be allowed to maximize its use in society within the bounds of copyright. Such use is within the spirit of copyright and its hope …

Storming Zuckerberg’S Castle, Anupam Chander

Georgetown Law Faculty Publications and Other Works

A company’s server is its castle, Richard Epstein once declared. Because of this, anyone sending an email to that server needs permission to enter. Within its own logic, this seems incontrovertible, but it depends on a few logical steps worth unpacking. It begins with the premise that a man’s home is his castle. (The masculine pronoun in the early formulation seems relevant.) Let us accept that premise for the purpose of argument. Combining this premise with the investiture of legal personhood on a corporation, we might then deduce that a company’s home must be its castle. Finally, combining that …

A Taxonomy Of Police Technology’S Racial Inequity Problems, Laura M. Moy

Georgetown Law Faculty Publications and Other Works

Over the past several years, increased awareness of racial inequity in policing, combined with increased scrutiny of police technologies, have sparked concerns that new technologies may aggravate inequity in policing. To help address these concerns, some advocates and scholars have proposed requiring police agencies to seek and obtain legislative approval before adopting a new technology, or requiring the completion of “algorithmic impact assessments” to evaluate new tools.

In order for policymakers, police agencies, or scholars to evaluate whether and how particular technologies may aggravate existing inequities, however, the problem must be more clearly defined. Some scholars have explored inequity in …

From Lex Informatica To The Control Revolution, Julie E. Cohen

Georgetown Law Faculty Publications and Other Works

Legal scholarship on the encounter between networked digital technologies and law has focused principally on how legal and policy processes should respond to new technological developments and has spent much less time considering what that encounter might signify for the shape of legal institutions themselves. This essay focuses on the latter question. Within fields like technology studies, labor history, and economic sociology, there is a well-developed tradition of studying the ways that new information technologies and the “control revolution” they enabled—in brief, a quantum leap in the capacity for highly granular oversight and management—have elicited long-term, enduring changes in the …

Congressional Oversight Of Us Intelligence Activities, Mary B. Derosa

Georgetown Law Faculty Publications and Other Works

This chapter examines the challenges, how they affect congressional oversight of intelligence, and Congress’s efforts to ensure accountability for United States (US) intelligence activities. The United States Government has engaged in intelligence collection and covert action since its earliest days. Congressional oversight of intelligence activities, however, has a relatively short history. It was not until the late 1940s, with the creation of the Central Intelligence Agency (CIA), that the US House of Representatives and Senate created entities – subcommittees of their Armed Services committees – with responsibility for intelligence oversight. The Church Committee revelations and other concerns that surfaced during …

Youth And Parent Health-Related Quality Of Life And Association With Glycemic Outcomes In Preadolescents And Adolescents With Type 1 Diabetes, Joan P. Totka, Julia A. Snethen, Elizabeth D. Cox

College of Nursing Faculty Research and Publications

Introduction

We explored differences in Health-Related Quality of Life (HRQOL) and the youth's glycosylated hemoglobin (A1c) of preadolescent and adolescent youths with type 1 diabetes (T1D) by individual (age, sex, race) and family (socioeconomic status) factors, and associations between youths’ HRQOL, their parents’ HRQOL, and youth's A1c.

Method

Correlational secondary analysis of baseline data from a randomized controlled trial testing a developmental intervention for youths with T1D and their parents from two diabetes clinics.

Results

Better adolescent HRQOL was associated with better glycemic control. Better preadolescent HRQOL was associated with better parent HRQOL. Non-White adolescents had worse HRQOL than White …

An Engaged Community-Academic Partnership To Promote Positive Youth Development, Kristin Haglund, Angela Ortiz, Johanna De Los Santos, Mauricio Garnier-Villarreal, Ruth Ann Belknap

College of Nursing Faculty Research and Publications

In this paper, we discuss how we cultivated a sustainable community-academic partnership and describe how our community-based participatory research project, Bembé Drum and Dance, contributed to youth development. Bembé Drum and Dance is an Afro-Latino performing arts program based on the positive youth development theory. Thirteen children ages 9–13 participated in the ensemble. We used a multimethod descriptive design. Data were gathered using surveys, participant observation, and interviews. Increases in the Five Cs (competence, confidence, connection, character, and caring) were noted among youth, most notably in competence and confidence. Recognizing that the project belonged to the community and supporting this …

Intensive Care Unit Nurse: Could We Call A Palliative Care Consult? Intensive Care Unit Provider: It's Too Early. Palliative Care Integration In The Intensive Care Unit: The Struggle To Translate Evidence Into Practice, Natalie S. Mcandrew, Jill L. Guttormson, Sean Marks, Mary Rhodes, Jayshil Patel, Colleen Mccracken

College of Nursing Faculty Research and Publications

Despite evidence regarding the value of palliative care, there remains a translation-to-practice gap in the intensive care setting. The purpose of this article is to describe challenges and propose solutions to palliative care integration through the presentation and discussion of a critical care patient scenario. We also present recommendations for a collaborative palliative care practice framework that holds the potential to improve quality of life for patients and families. Collaborative palliative care is characterized by close working relationships with families, interprofessional intensive care unit healthcare teams, and palliative care specialists. The shortage of palliative care specialists has become a pressing …

Safety And Efficacy Of Balloon-Mounted Stent In The Treatment Of Symptomatic Intracranial Atherosclerotic Disease: A Multicenter Experience, Mahmoud H. Mohammaden, Raul G. Nogueira, Wondwossen G. Tekle, Santiago Ortega-Gutierrez, Mudassir Farooqui, Cynthia B. Zevallos, Ricardo Hanel, Gustavo M. Cortez, Amin Aghaebrahim, Ameer E. Hassan

School of Medicine Publications

Background Randomized clinical trials have failed to prove that the safety and efficacy of endovascular treatment for symptomatic intracranial atherosclerotic disease (ICAD) is better than that of medical management. A recent study using a self-expandable stent showed acceptable lower rates of periprocedural complications.

Objective To study the safety and efficacy of a balloon-mounted stent (BMS) in the treatment of symptomatic ICAD.

Methods Prospectively maintained databases from 15 neuroendovascular centers between 2010 and 2020 were reviewed. Patients were included if they had severe symptomatic intracranial stenosis in the target artery, medical management had failed, and they underwent intracranial stenting with BMS …

Development Of A Digital Toolkit To Improve Quality Of Life Of Patients With Systemic Lupus Erythematosus, Jerik Leung, Laura Kloos, Alfred H Kim, Elizabeth A Baker

2020-Current year OA Pubs

OBJECTIVE: The purpose of this manuscript is to detail development and initial usability testing of an e-toolkit designed to provide skills and knowledge around self-management behaviors for individuals living with systemic lupus erythematosus.

METHODS: Researchers worked with a steering committee of patients and providers to (1) develop a clickable prototype of an e-toolkit and (2) conduct alpha (individuals not affiliated with an academic clinic as patient or provider) and beta (individual patients with systemic lupus erythematosus as well as members of the clinic healthcare team and individuals who work in patient advocacy organizations) usability testing through semistructured interviews.

RESULTS: During …

Decline In Subarachnoid Haemorrhage Volumes Associated With The First Wave Of The Covid-19 Pandemic, Than N. Nguyen, Diogo C. Haussen, Muhammad M. Qureshi, Hiroshi Yamagami, Toshiyuki Fujinaka, Ossama Y. Mansour, Mohamad Abdalkader, Michael Frankel, Zhongming Qiu, Ameer E. Hassan

School of Medicine Publications

Background During the COVID-19 pandemic, decreased volumes of stroke admissions and mechanical thrombectomy were reported. The study’s objective was to examine whether subarachnoid haemorrhage (SAH) hospitalisations and ruptured aneurysm coiling interventions demonstrated similar declines.

Methods We conducted a cross-sectional, retrospective, observational study across 6 continents, 37 countries and 140 comprehensive stroke centres. Patients with the diagnosis of SAH, aneurysmal SAH, ruptured aneurysm coiling interventions and COVID-19 were identified by prospective aneurysm databases or by International Classification of Diseases, 10th Revision, codes. The 3-month cumulative volume, monthly volumes for SAH hospitalisations and ruptured aneurysm coiling procedures were compared for the period …

Variations In Anterior Segment Vasculature Of The Eye And Their Implication In Strabismus Surgery And Other Surgical Procedures, Adam L. Lewis, Clayton Marolt, M. Scott Draper, Victoria Gordon, Kenneth S. Johnson, Joanna Rowe, Kanwalgeet Hans, Steven M. Silverstein, Anthony Olinger

Faculty and Staff Publications

Objective:

Anterior segment ischemia (ASI) is a serious complication of strabismus surgery and other ocular procedures. The purpose of this study is to evaluate variation of the long posterior artery (LPCA). These variations may predispose patients to anterior segment ischemia following strabismus surgery, and proper mapping may provide surgical “danger zones” for other invasive ocular procedures.

Subjects:

A total of 100 preserved cadaveric eyeballs from University of Nebraska Medical Center (UNMC), Creighton University, and Kansas City University (KCU) were utilized for this study.

Methods:

LPCAs were identified, isolated, and counted prior to removal of the choroid. Two distances were measured …

French Military Masculinities And The Birth Of Cinéma Colonial: Triangulating Queer Desire In Jacques Feyder’S L’Atlantide (1921), Barry Nevin

Articles

Jacques Feyder’s L’Atlantide (1921) is widely considered not only cinéma colonial’s first major representative example but also one of the genre’s most emblematic narratives. However, ambiguities in the film’s portrayal of the mission civilisatrice have received comparatively little analysis. This article aims to expand on our understanding of L’Atlantide and the mirror it held up to interwar France in three main stages. First, it situates the film’s discourses of gender and colonialism within present post-colonial scholarship. Second, it analyses the aesthetic and political contexts of L’Atlantide, paying particular attention to how the film offered a remedy to France’s ailing postwar …

Politics At The Pulpit: Elite Religious Cues And Immigration Attitudes, Benjamin Knoll, Matthew Baker

Commonwealth Review of Political Science

Previous scholarship has demonstrated a link between religiosity and immigration attitudes, often inferring the effect of cues from religious leaders as the motivating source. This study directly examines the “elite cues” linking mechanism with an experiment embedded in a nationally representative public opinion survey. We improve on previous research designs by introducing a pretest that measures immigration policy attitudes among respondents which can then be directly compared to posttest measures after the introduction of the elite cue stimulus. Multivariate analysis of the survey results reveal no support for the elite cues explanation. We discuss the implications of these findings for …

Building Services Engineering January/February

Building Services Engineering

No abstract provided.

Attuning To Need: Reconceptualizing “Help” In Poor Rural Areas, Jennifer M. Frank, Laura Brierton Granruth, Brittany Leffler, Rachel Preibisch, Dawn Watson, Heather Girvin, Mary Glazier

Contemporary Rural Social Work Journal

Social isolation is closely linked to overall health and well-being and is a serious concern for those in rural areas. Our research seeks insights into the needs experienced in poor rural areas by utilizing letter writing between students and community agency participants as a research methodology. In the letters, we observed that community participants relied upon friend and family style relationships and even viewed their agency relationships as such. This suggests that transforming "professional helping relationships" into alliances that are less impersonal might be in order. Such relationships and connections seemed conducive to the development of empowering self-efficacy. This finding …

Recalibrating Directors’ Liabilities Amidst Technological Flux, Pey Woan Lee, Susanna Leong

Research Collection Yong Pung How School Of Law

In this chapter, we consider how to balance corporate innovation and personal liability in the specific context of directors’ exposure to personal liability for corporate copyright infringements. Directors may incur personal liability in the statutory context if they have ‘authorised’ the company’s infringement, or at common law if they acted as the company’s joint tortfeasor. Due to the conflicting policy goals of encouraging innovation whilst preserving personal accountability, we observe that this regime is unsatisfactory. Delving into the modern history of copyright law, we seek to demonstrate that directors of technological companies operate in an environment of high legal uncertainty …

Governing Science And Technology Under The International Economic Order: Regulatory Divergence And Convergence In The Age Of Megaregionals By Shin-Yi Peng, Han-Wei Liu And Ching-Fu Lin, Henry S. Gao, Weihuan Zhou

Research Collection Yong Pung How School Of Law

Trade and technology have a long history of interdependence. It was the trade along the ancient silk road that helped to spread the technologies of China – such as paper-making, gun power, compass, and moveable type printing – to Europe. These technologies helped to launch the Renaissance, the Reformation, and the Great Discoveries, which in turn set in motion globalization as we know today. As we enter the third decade of the twenty-first century, the role of science and technology grows even stronger in international trade. For example, the advancement of information and communications technology (ICT) has greatly facilitated the …

Spandeck: A Relational View Of The Duty Of Care, Kian Peng Soh

Research Collection Yong Pung How School Of Law

The use of a general framework in the determination of a duty of care has seemingly fallen out of favour following the UK Supreme Court’s decision in Robinson. Relying on the example of the Spandeck framework in Singaporean jurisprudence, this piece presents the argument that such frameworks, being consistent with a relational conception of tort law, can provide a useful means of determining whether a duty of care exists. In so doing, this piece addresses some criticisms of the relational view and re-emphasises the important role the duty of care plays in the tort of negligence.

The Confederate Surrender At Tiptonville And The Conclusion Of The Island No. 10 Campaign

Jackson Purchase Historical Society Journal Archive

The Confederate Surrender at Tiptonville and the Conclusion of the Island No. 10 Campaign

Dieter C. Ullrich

Hidden Bias In Empirical Textualism, Matthew C. Jennejohn, D. Carolina Nunez, Samuel Nelson

Faculty Scholarship

A new interpretive technique called “corpus linguistics” has exploded in use over the past five years from state supreme courts and federal courts of appeals to the U.S. Supreme Court. Corpus linguistics involves searching a large database, or corpus, of text to identify patterns in the way in which a certain term is used in context. Proponents of the method argue that it is a more “empirical” approach than referencing dictionaries to determine a word’s public meaning, which is a touchstone in originalist approaches to legal interpretation.

This Article identifies an important concern about the use of corpus linguistics in …