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2021

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Pineal Gland Abnormalities And The Relationship Of Melatonin To The Development And Symptom Severity Of Schizophrenia: An Integrative Review Of The Literature, Kathryn Margretta Jan 2021

Pineal Gland Abnormalities And The Relationship Of Melatonin To The Development And Symptom Severity Of Schizophrenia: An Integrative Review Of The Literature, Kathryn Margretta

Honors Undergraduate Theses

The purpose of this thesis is to critique the literature focusing on the role of pineal gland volume and function and the development of schizophrenia by asking the question, "What is the relationship between pineal gland physiologic function and development and symptom severity of schizophrenia? It is crucial that health care providers continue advocate for better understanding of schizophrenia in order to develop a more appropriate treatment and relive the suffering of those with schizophrenia. A review of published literature focusing on the pineal glands association with schizophrenia was performed using several databases including: ScienceDirect, PubMED, Google Scholar, Cumulated Index …

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Workspace And Kinematic Modeling And Analysis Of Semi-Robotic Laparoscopic Surgery, Immanuel E. Girgis Jan 2021

Workspace And Kinematic Modeling And Analysis Of Semi-Robotic Laparoscopic Surgery, Immanuel E. Girgis

Honors Undergraduate Theses

Laparoscopic Surgery has been revolutionized by the world of Surgical Robotics. Robot-Assisted Surgeries have been proven to have many advantages over the fundamental, traditional "by-hand" procedures previously conducted, and still currently being done for certain operations. Robot-assisted surgery may offer benefits to patients through the use of minimally invasive techniques, which may result in reduced blood loss, reduced blood transfusion, fewer complications, reduced postoperative pain, shorter hospital stays, and reduced recovery times (Ho et al., 2011). Studies have proven that robotic surgery may lead to patients recovering faster depending on the timeframe and the type of procedure (Tang et al., …

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Using Genetics In A Model Organism To Understand Polyamine Transport, Victoria A. Millington Jan 2021

Using Genetics In A Model Organism To Understand Polyamine Transport, Victoria A. Millington

Honors Undergraduate Theses

Polyamines are small positively charged molecules that control major vital cellular processes including cell growth and proliferation, gene expression, protein production and cell death. Cells can obtain polyamines by making them (biosynthesis) or bringing them into the cell from the outside (transport). Cancer cells require high levels of polyamines to sustain their rapid growth, and depletion of polyamines slows the growth of malignant cells. An FDA approved drug, difluoromethylornithine (DFMO), blocks biosynthesis but is often ineffective because tumor cells respond by increasing transport of polyamines. Thus, a dual therapy that simultaneously targets polyamine biosynthesis and transport is needed. The mechanism …

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Fish Weirs Et Alia: A Gis Based Use-Analysis Of Artificial, Pre-Columbian Earthworks In West Central Llanos De Mojos, Bolivia, Charlotte A. Robinson Jan 2021

Fish Weirs Et Alia: A Gis Based Use-Analysis Of Artificial, Pre-Columbian Earthworks In West Central Llanos De Mojos, Bolivia, Charlotte A. Robinson

Honors Undergraduate Theses

This study employed a GIS-based use-analysis on a network of recently mapped pre-Columbian earthworks lying on the west side of a Bolivian floodplain. This wetland region, called Llanos de Mojos, is home to many different types of artificial mounds that served different roles for the ancient communities who constructed them thousands of years ago. This new set of features, which was mapped by volunteers of the Proyecto Sistemas Informaticas Geograficas y Arqueologicas del Beni (ProSIGAB) was purported to be a network of fish weirs, linear earthworks built in rivers or floodplains that are designed to trap fish by exploiting seasonal …

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A Right To A Pollution-Free Environment Through The Right To Life, Natalie S. Mousa Jan 2021

A Right To A Pollution-Free Environment Through The Right To Life, Natalie S. Mousa

Honors Undergraduate Theses

Since humans have existed on Earth, the environment has been one of the primary resources contributing to humans' ability to live life adequately. Pollution has not only destroyed natural life, but it has also diminished humans' right to life. The United Nations 1966 International Covenant on Civil and Political Rights (ICCPR) guarantees "every human being has the inherent right to life," but how can one exercise this right in an environment that is degrading through pollution? This is the basis of which this thesis is surrounded; the issue of environmental pollution hindering humans' right to life. Thus, this thesis …

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Disease And Democracy: Understanding The Impact Of Disease Burden On Civil Liberties And Civil Society In Sub-Saharan Africa, Abigail E. Reynolds Jan 2021

Disease And Democracy: Understanding The Impact Of Disease Burden On Civil Liberties And Civil Society In Sub-Saharan Africa, Abigail E. Reynolds

Honors Undergraduate Theses

What is the impact of disease burden on democracy in sub-Saharan Africa? Despite increasing interest in the implications of health crises for state stability, there has been a dearth of literature exploring the relationship between disease burden more generally and democracy specifically. This thesis takes a comprehensive approach to bridge this gap in the literature. Using quantitative and qualitative methods, it draws on data from the Global Burden of Disease database and the Varieties of Democracy (V-Dem) dataset to analyze this relationship. The diseases studied are categorized as long-wave (e.g., HIV/AIDS and tuberculosis), short-wave (e.g., Ebola and lower respiratory infections), …

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Phototransduction Components In The Visual System Of Hard-Bodied Ticks, Arimar J. López Limas Jan 2021

Phototransduction Components In The Visual System Of Hard-Bodied Ticks, Arimar J. López Limas

Honors Undergraduate Theses

Ticks are terrestrial invertebrate parasites that attach to their hosts to feed on their blood. Ticks are composed of three families: Ixodidae, Argasidae, and Nuttalliellidae. Ixodid ticks include members of the genera Amblyomma, Ixodes, Haemaphysalis, Hyalomma, Dermacentor, and Rhipicephalus. Ticks can transmit diseases to animals and humans, making them an important organism to study. Current tick-bite mitigation strategies include acaricides (harmful if misused), and CO2 traps (effective in decreasing tick abundance, but costly to use). Since the visual system of ticks has not been studied extensively, I expect that by studying their visual system, alternative tick-bite mitigation …

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Examining Everyday Literacies: An Autoethnographic Analysis Of Mundane Textualities, Kyle J. Mauter Jan 2021

Examining Everyday Literacies: An Autoethnographic Analysis Of Mundane Textualities, Kyle J. Mauter

Honors Undergraduate Theses

As a way of extending perspectives of writing and learning, this thesis explores everyday literacy activities and their role in function in shaping people's activities. Taking up an autoethnographic approach to studying the mundane literacies of everyday life, this thesis offers a fine-grained analysis of the processes and practices involved in two specific literate activities I have engaged in over the two years: creating a mixtape for a friend and streaming my participation in online video games. As key findings, the analysis of these everyday literate activities suggests that the interactions between people and social contexts figure prominently in the …

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The Australian Paradox: Politics Of An Energy Transition, Lindsay H. Bushing Jan 2021

The Australian Paradox: Politics Of An Energy Transition, Lindsay H. Bushing

Honors Undergraduate Theses

The 1973 oil shock was the first energy crisis modern industrialized economies experienced. The disruption exposed the limitations of energy systems that rely on fossil fuels, creating a demand for experimentation of energy alternatives. In their book, Renewables: The Politics of a Global Energy Transition, Michaël Aklin, and Johannes Urpelainen provide a framework to analyze this transitionary period for selected countries, as well as the events that provoke the need for change in the form of the 1970s external shocks in oil prices. In this paper, for the first time, Aklin & Urpelainen's framework will be applied to Australia …

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Recapture: A Virtual Reality Interactive Narrative Experience Concerning Perspectives And Self-Reflection, Indira Avendano Jan 2021

Recapture: A Virtual Reality Interactive Narrative Experience Concerning Perspectives And Self-Reflection, Indira Avendano

Honors Undergraduate Theses

This project presents a virtual reality (VR) Interactive Narrative aiming to leave users reflecting on the perspectives one chooses to view life through. The narrative is driven by interactions designed using the concept of procedural rhetoric, which explores how rules and mechanics in games can persuade people about an idea, and Shin's cognitive model, which presents a dynamic view of immersion in VR. The persuasive nature of procedural rhetoric in combination with immersion techniques such as tangible interfaces and first-person elements of VR can effectively work together to immerse users into a compelling narrative experience with an intended emotional response …

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Chinese Paradox : Where Are Chinese Monuments?, Alberto Castelli Jan 2021

Chinese Paradox : Where Are Chinese Monuments?, Alberto Castelli

Journal of Urban Culture Research

The bareness of the Chinese monumental landscape is the result of various factors, the analysis of which deserves an inquiry into Chinese modus vivendi. Daoist imprimatur and its recognition of nature’s superiority is but one. Buddhist sectarianism, Chinese fluid conception of time, Chinese iconoclasm, are phenomena that, largely, have concurred on creating a periodic tabula rasa of cultural heritage. Making sense of this is simply to recognize that artistic representations are not only metaphors for understanding social dynamics, but also a magnifying glass on the relation between people and their past.

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The Process Of Creating A Work Of Art From Sensory Integration Of Students With Intellectual Disabilities Of The Panyanukul Schools In Eastern Thailand, Tuenrudee Rugmai Jan 2021

The Process Of Creating A Work Of Art From Sensory Integration Of Students With Intellectual Disabilities Of The Panyanukul Schools In Eastern Thailand, Tuenrudee Rugmai

Journal of Urban Culture Research

The research was based on creating art together with children with intellectual disabilities. In this study, art therapy was applied along with sensory integration. The objectives are to determine the process of creating art from sensory integration of children with intellectual disabilities in order to develop model activities for art classes and explore how to develop products from artworks created by children with intellectual disabilities, which can generate income for the children and the communities. In this qualitative research, the data were collected as a volunteer in the field and analyzed to determine the process of creating a work of …

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Futurism In Conceptual Textile Art : An Approach To Improving Sanitation In Ghana, William Badoe, Frederick Boamah Jan 2021

Futurism In Conceptual Textile Art : An Approach To Improving Sanitation In Ghana, William Badoe, Frederick Boamah

Journal of Urban Culture Research

Century old art movements have become relevant in modern art especially in conceptual art to address societal issues. Ghana is confronted with sanitation issues of which government interventions have proved futile in dealing with the situation. This art studio experimental study explored the philosophy concept of futurism through conceptual textile art towards sanitation improvement in Ghana. The Studio-Based research approach was employed with adoption of Aesthetico-Action Research model in generating the results. The results revealed that conceptual textile art could be used as a communicative tool through the concept of futurism as the driving force. The results proved the possibility …

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Brain Interhemispheric Alterations In Attention-Deficit Hyperactivity Disorder Using Structural Neuroimaging Features, Cintya Dutta Jan 2021

Brain Interhemispheric Alterations In Attention-Deficit Hyperactivity Disorder Using Structural Neuroimaging Features, Cintya Dutta

Electronic Theses and Dissertations, 2020-2023

This dissertation examines brain lateralization and interhemispheric asymmetry patterns found in youths with Attention-Deficit / Hyperactivity Disorder (ADHD). Prior research groups have found mixed findings with respect to left and right hemisphere alterations from ADHD subjects using structural magnetic resonance imaging. In these investigations, we propose the use of Asymmetry Index (AI), a subject-specific metric that quantifies the extent of brain asymmetry and allows each subject to serve as their own control, thus reducing variability when pooling across different sites. We compare AI metric with laterality across volumetric, surface area, thickness, morphology, and white matter measures in order to characterize …

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The Impact Of Misspecification Of Within-Person Autocorrelated Covariance Structure On Nonlinear Latent Growth Curve Models: A Monte Carlo Simulation Study, Mingming Zhou Jan 2021

The Impact Of Misspecification Of Within-Person Autocorrelated Covariance Structure On Nonlinear Latent Growth Curve Models: A Monte Carlo Simulation Study, Mingming Zhou

Electronic Theses and Dissertations, 2020-2023

The purpose of this study was to assess the effects of misspecification (i.e., under-specification, over-specification, and general misspecification) of the within-person level errors in longitudinal data under quadratic, exponential, and logistic latent growth curve models and to make a contribution to the literature in this area. A Monte Carlo simulation in R uncovered a common bias pattern throughout this study. For under-specification of autocorrelated processes and general misspecification of MA as AR, the mean intercept was more likely to be downward- biased, but the linear slope and nonlinear slope for an individual tend to be upward-biased. On average, the variation …

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Downregulation Of Mir-34a Via Calorie Restriction Regulates Lipid Metabolism In The Liver Of Long-Living Ames Dwarf Mice, Sarah Ashiqueali Jan 2021

Downregulation Of Mir-34a Via Calorie Restriction Regulates Lipid Metabolism In The Liver Of Long-Living Ames Dwarf Mice, Sarah Ashiqueali

Electronic Theses and Dissertations, 2020-2023

Ames dwarf mice (df/df) display delayed aging relative to their normal siblings, living approximately 40-60% longer. As such, investigating the mechanisms that enable these organisms to have superior life expectancies may prove useful in developing therapies to slow aging and deter age-related disease. Nonalcoholic fatty liver disease (NAFLD) is a condition that is characterized by the accumulation of excess adipose tissue in the liver. Interestingly, its prevalence tends to increase with age with an incidence rate of greater than 40% in individuals over the age of 60. Previous studies highlight the potential of calorie restriction (CR) in promoting longevity, but …

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An Examination Of Factors Associated With Lgbtq+ College Students' Adoption Of Post-Exposure Prophylaxis (Pep) As An Hiv Prevention Method, Shayna Forgetta Jan 2021

An Examination Of Factors Associated With Lgbtq+ College Students' Adoption Of Post-Exposure Prophylaxis (Pep) As An Hiv Prevention Method, Shayna Forgetta

Electronic Theses and Dissertations, 2020-2023

Post-exposure prophylaxis (PEP) is an effective human immunodeficiency virus (HIV) prevention medication taken after exposure, yet it is not widely used in the lesbian, gay, bisexual, transgender, and queer/questioning (LGBTQ+) community. Understanding its acceptability is vital, given this population's increased risk for contracting HIV. Drawing from the Health Literacy Skills Framework and the Theory of Planned Behavior, this study provides an examination of PEP-related awareness and knowledge, as well as intention to request and use PEP. Using a cross-sectional survey design, a convenience sample of 131 LGBTQ+ college students from a Southeastern university was recruited through email and social media. …

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On The Strategic Relationship Between Leadership And Innovation In Us Firms, Shabeer Kirmani Jan 2021

On The Strategic Relationship Between Leadership And Innovation In Us Firms, Shabeer Kirmani

Electronic Theses and Dissertations, 2020-2023

Leadership is one of the most important factors in organizational success. Innovation is another of most important factors in organizational success. Leaders play a pivotal role in the innovation capabilities of organizations. One of the most important areas in Leadership Studies (LS) is the association between leadership style and the firm's innovation performance, but a lack of understanding and consensus still remains as a major issue. This research aims to address the research gap by reviewing the empirical literature and determining how the ambidextrous leadership (transactional and transformational) styles in top level U.S. management (CEOs) are related with firm ambidextrous …

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Engaging Elementary Preservice Teachers In Reflection For, In, And On Practice During An Approximation Of Practice In Teachlivetm Using Sentence Frames For English Language Learners, Courtney Lopas Jan 2021

Engaging Elementary Preservice Teachers In Reflection For, In, And On Practice During An Approximation Of Practice In Teachlivetm Using Sentence Frames For English Language Learners, Courtney Lopas

Electronic Theses and Dissertations, 2020-2023

The purpose of this study was to explore how a teacher educator (myself) and preservice teachers engaged in joint reflection-for-action, reflection-in-action, and reflection-on-action during an approximation of practice in a TeachLivETM setting using sentence frames to support English Language Learners' (ELLs') writing. Four elementary education preservice teachers participated in this study based on set inclusion criteria. This action research study included video-recorded approximations of practice, the sentence frames preservice teachers submitted in the skill seven module, reflective journaling, and analytic memoing. Instructional sequence analysis through transcription, holistic coding, message units, action units, interaction units, instructional sequences, and phase units were …

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The Effect Of Dynamic Span Wise Bending On The Forces Of A Pitching Flat Plate, Manoj Prabakar Sargunaraj Jan 2021

The Effect Of Dynamic Span Wise Bending On The Forces Of A Pitching Flat Plate, Manoj Prabakar Sargunaraj

Electronic Theses and Dissertations, 2020-2023

A novel experiment has been conducted to investigate the effect of dynamic spanwise bending on the formation of a dynamic stall vortex on a rapidly pitching flat plate. Experiments have been performed in a towing tank at different nondimensional pitch rates (Kp) in the range of 0.4112 < Kp < 0.8225, and four maximum pitch angles (30° , 45°, 60°, and 90°) at a Reynolds number of 12,000. Synchronized direct force measurements and particle image velocimetry (PIV) are used to characterize the effect of bending on the unsteady forces and the flow field. An unsteady analytical model based on the bending and pitching kinematics is used to model the lift force histories. It is found that a spanwise bending of a pitching wing alleviated the unsteady lift forces. However, the main contribution was found to come from the non-circulatory forces. The circulation and pressure analysis of the pitching wing revealed little or no sensitivity to the wing bending motions examined.

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A Holistic Approach For Power Systems Using Machine Learning And System Dynamics, Bibi Ibrahim Jan 2021

A Holistic Approach For Power Systems Using Machine Learning And System Dynamics, Bibi Ibrahim

Electronic Theses and Dissertations, 2020-2023

The growing digital economy has imposed greater demand on the electricity supply's reliability in the past decades, with more consumers and electric vehicles (EV) becoming connected to the electric grid. While the uncertainty of the outcomes is unavoidable, there is a need for more accurate forecasts, modeling tools, and detailed roadmaps that can support the reliable transitioning of power systems. Predicting the electricity demand growth will allow energy managers to understand consumer demand in the near future better. However, there are challenges for forecasting the peak demand growth since it is very difficult to model the various complex features that …

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Influence Of Geography On The Healthy Gut Microbiome And The Role Of The Gut Microbiome In Ibd Symptom And Disease Progression, Sayf Al-Deen Hassouneh Jan 2021

Influence Of Geography On The Healthy Gut Microbiome And The Role Of The Gut Microbiome In Ibd Symptom And Disease Progression, Sayf Al-Deen Hassouneh

Electronic Theses and Dissertations, 2020-2023

The human gut microbiome is believed to play an integral role in host health and disease. In a microbial community, associations between constituent members play an important role in determining the overall structure and function of the community. To understand the nature of bacterial associations at the species level in healthy human gut microbiomes, we analyzed previously published collections of whole-genome shotgun sequence data, from fecal samples obtained from four different healthy human populations. Using a Random Forest Classifier, we identified bacterial species that were prevalent in these populations and whose relative abundances could be used to accurately distinguish between …

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Genomic And Physiological Bioremediation Characteristics Of The Actinobacteria Frankia, Erik Swanson Jan 2021

Genomic And Physiological Bioremediation Characteristics Of The Actinobacteria Frankia, Erik Swanson

Doctoral Dissertations

Introduction: Frankia is a genus of symbiotic, nitrogen fixing actinobacteria found in the soil and root tissue of actinorhizal plants throughout the world. Both Frankia and actinorhizal plants are resistant to a wide range of environmental and chemical stresses including heavy metals, high salinity, and drought. This makes Frankia and the actinorhizal symbiosis an interesting candidate for bioremediation applications. However, the microbial community found in the actinorhizal rhizosphere and surrounding soil has been implicated in some of the symbiotic and resistance traits attributed to Frankia. This necessitates thorough investigation of the genomic and genetic components of any bioremediation traits possessed …

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The Ideal International Student: Intersections Of Race, Gender, And Accent In International Multilingual Student Identity, Kristin Raymond Jan 2021

The Ideal International Student: Intersections Of Race, Gender, And Accent In International Multilingual Student Identity, Kristin Raymond

Doctoral Dissertations

Perceptions of international multilingual students from the university community have a significant impact on those students’ identities and status on campus. These perceptions construct narratives of the ideal international multilingual student, which is defined by an optimal set of student characteristics that appear to be divorced from factors of race, gender, and accent. This dissertation examines the concept of the ideal international multilingual student in intersection with factors of race, gender, and accent. This qualitative, IRB-approved study draws from the model of investment (Norton 2000, 2013; Darvin & Norton, 2015; De Costa & Norton, 2017) and the concept of racialization …

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Synthesis Of Thioacids And Dicarboxylic Acids Derived From Open Β-Lactams For Inhibition Of Metallo-Β-Lactamases, Junfu Chen Jan 2021

Synthesis Of Thioacids And Dicarboxylic Acids Derived From Open Β-Lactams For Inhibition Of Metallo-Β-Lactamases, Junfu Chen

Doctoral Dissertations

Antibiotics are important substances that have been used in clinical treatment for over 70 years. Because of overuse and misuse of antibiotics, bacteria developed resistance. However, bacterial resistance towards antibiotics, especially the β-lactam antibiotics, is becoming increasingly threat. Currently, the β-lactam antibiotics are seriously threatened by β-lactamases. Metallo-β-lactamases (MBLs), a sub-class of β-lactamases, have been found in several bacteria since they confer resistance to many different β-lactams, and as a result, the bacteria survive in their presence. A potential treatment is to synthesize inhibitors of MBLs, however, there are no inhibitors synthesized in clinical use. The goal of this project …

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The Effect Of Deep-Water Multibeam Mapping Activity On The Foraging Behavior Of Cuvier’S Beaked Whales And The Marine Acoustic Environment, Hilary Suzanne Curran Kates Varghese Jan 2021

The Effect Of Deep-Water Multibeam Mapping Activity On The Foraging Behavior Of Cuvier’S Beaked Whales And The Marine Acoustic Environment, Hilary Suzanne Curran Kates Varghese

Doctoral Dissertations

Sound can propagate great distances underwater and is an important mode for marine life to obtain information. Human activities in the ocean such as global shipping, coastal construction, gas and oil exploration, and mapping navigation routes intentionally and unintentionally emit sound into the ocean, potentially interacting with marine life. Therefore, it is essential that the effects of anthropogenic noise on marine life and the ambient marine acoustic environment be understood. Most of the work, to date, has focused on the impact of low-frequency (<1 kHz) sources such as shipping noise, which is ubiquitous in the ocean, and mid-frequency (1-10 kHz) sources such as naval sonar, to which many marine mammals have shown to be sensitive. The effect of these sources can be as salient as a mass stranding event or as benign as an animal swimming away from a source of noise with no other effect. Less work has focused on higher frequency sources (>10 kHz), including ocean-mapping sonar systems. However, most marine mammals, namely toothed whales (odontocetes), are capable …

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Without Religion W(H)Ither Family Law?, Anita Bernstein Jan 2021

Without Religion W(H)Ither Family Law?, Anita Bernstein

Faculty Scholarship

No abstract provided.

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2021-2022 Halmos College Of Arts And Sciences Graduate Program Catalog, Nova Southeastern University Jan 2021

2021-2022 Halmos College Of Arts And Sciences Graduate Program Catalog, Nova Southeastern University

Halmos College of Arts and Sciences Course Catalogs

No abstract provided.

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Naturally Occurring Rock Type Influences The Settlement Of Fucus Spiralis L. Zygotes, William G. Ambrose, Paul E. Renaud, David C. Adler, Robert L. Vadas Jan 2021

Naturally Occurring Rock Type Influences The Settlement Of Fucus Spiralis L. Zygotes, William G. Ambrose, Paul E. Renaud, David C. Adler, Robert L. Vadas

Marine Science

The settlement of spores and larvae on hard substrates has been shown to be influenced by many factors, but few studies have evaluated how underlying bedrock may influence recruitment. The characteristics of coastal rock types such as color, heat capacity, mineral size, and free energy have all been implicated in settlement success. We examined the influence of naturally occurring rock types on the initial attachment of zygotes of the brown alga Fucus spiralis Linnaeus 1753. We also assessed the dislodgment of zygotes on four bedrock types after initial attachment in laboratory experiments using wave tanks. Settling plates were prepared from …

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Patient-Derived Induced Pluripotent Stem Cell Models For Phenotypic Screening In The Neuronal Ceroid Lipofuscinoses, Ahmed Morsy, Angelica V. Carmona, Paul C. Trippier Jan 2021

Patient-Derived Induced Pluripotent Stem Cell Models For Phenotypic Screening In The Neuronal Ceroid Lipofuscinoses, Ahmed Morsy, Angelica V. Carmona, Paul C. Trippier

Journal Articles: Pharmaceutical Sciences

Batten disease or neuronal ceroid lipofuscinosis (NCL) is a group of rare, fatal, inherited neurodegenerative lysosomal storage disorders. Numerous genes (CLN1-CLN8, CLN10-CLN14) were identified in which mutations can lead to NCL; however, the underlying pathophysiology remains elusive. Despite this, the NCLs share some of the same features and symptoms but vary in respect to severity and onset of symptoms by age. Some common symptoms include the progressive loss of vision, mental and motor deterioration, epileptic seizures, premature death, and in the rare adult-onset, dementia. Currently, all forms of NCL are fatal, and no curative treatments are available. Induced pluripotent stem …

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