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การออกแบบเรขศิลป์เพื่อเตรียมพร้อมรับภัยพิบัติสำหรับเจเนอเรชันแอลฟ่า, โชติกานต์ สัตย์ซื่อ

Chulalongkorn University Theses and Dissertations (Chula ETD)

ปัญหาความไม่ปลอดภัยในชีวิตของเด็กและเยาวชนซึ่งส่งผลให้เด็กและเยาวชนของประเทศเสียชีวิต บาดเจ็บ และพิการในแต่ละปีเป็นจำนวนมาก โดยเกิดจาก การบาดเจ็บที่เกิดจากภัยพิบัติทางธรรมชาติในรูปแบบต่างๆ เช่น อุทกภัย วาตภัย อัคคีภัย เป็นต้นเนื่องจากสภาพแวดล้อมของชุมชนมีความเสี่ยงอยู่เดิมก่อนเกิดเหตุแต่ไม่ได้แก้ไข ประกอบกับผู้ปกครองคิดว่าลูกสามารถดูแลตัวเองได้ โดยที่ไม่เคยตรวจสอบหรือฝึกทักษะให้ลูก เช่น การข้ามถนน การว่ายน้ำ เป็นต้น ดังนั้น ครูและผู้ปกครองควรสอนทักษะให้เด็กสามารถช่วยตัวเองให้รอดจากภัยพิบัติทางธรรมชาติหรืออุบัติเหตุเพื่อลดอัตราการเสียชีวิตลง ผู้วิจัยจึงได้คิดค้นเว็บไซต์ แอปพลิเคชั่นและ Ebook เพื่อเตรียมคความพร้อมรับมือกับภัยพิบัติทางธรรมชาติ โดยสอดแทรกเกมเพื่อให้เหมาะกับวัยที่ชื่นชอบการเรียนรู้ผ่านการเล่น และเพื่อการจดจำได้ง่ายจึงใช้คาแรคเตอร์ที่เป็นตัวแทนปกป้องจากภัยพิบัติต่างๆ เข้ามาช่วย

ผลของโคลชิซินต่อตัวชี้วัดทางชีวภาพที่แสดงพังผืดในไตในผู้ป่วยโรคไตเสื่อมเรื้อรัง, ธันยธร วุฒิพุธนันท์

Chulalongkorn University Theses and Dissertations (Chula ETD)

ที่มา: การเกิดพังผืดในไตและการอักเสบเรื้อรังเป็นปัจจัยหลักที่นำไปสู่การเกิดไตเสื่อมเรื้อรัง การใช้ยา colchicine ซึ่งมีคุณสมบัติยับยั้งการอักเสบและลดการสร้างพังผืด จึงน่าจะช่วยชะลอการดำเนินโรคของโรคไตเสื่อมเรื้อรังได้ วิธีการศึกษา: การศึกษานี้เป็น randomized, double-blind, placebo-controlled trial โดยผู้วิจัยได้สุ่มผู้เข้าร่วมวิจัยที่มีโรคไตเสื่อมเรื้อรังระยะที่ 3 และ 4 เป็นสองกลุ่มด้วยอัตราส่วน 1:1 คือกลุ่มแรกให้ colchicine 0.6 mg รับประทานวันเว้นวัน และกลุ่มที่สองให้ยาหลอก การวิจัยนี้ได้ศึกษา primary outcome เป็นการเปลี่ยนแปลงของ urine transforming growth factor beta-1 (TGF-β1) หลังได้ยานาน 12 สัปดาห์ และ secondary outcome ศึกษาการเปลี่ยนแปลงของ urine monocyte chemotactic protein-1 (MCP-1), การเปลี่ยนแปลงการทำงานของไต ตัวชี้วัดการอักเสบเรื้อรัง และผลข้างเคียงจากยา ผลการศึกษา: มีผู้เข้าร่วมวิจัยทั้งหมด 40 ราย ไม่พบการเปลี่ยนแปลง urine TGF-β1 อย่างมีนัยสำคัญทางสถิติที่แตกต่างกันระหว่างสองกลุ่ม ส่วน secondary outcome นั้น ไม่พบว่าค่าการทำงานของไต และ C-reactive protein ต่างกัน แต่พบว่าในกลุ่ม colchicine มี white blood cell count, absolute neutrophil count, neutrophil-to-lymphocyte ratio และ platelet count ลดลงมากกว่าอย่างมีนัยสำคัญทางสถิติ อย่างไรก็ตาม พบว่าในกลุ่ม colchicine มีการเพิ่มขึ้นของ urine MCP-1 มากกว่ากลุ่มยาหลอก ส่วนผลข้างเคียงจากยาไม่แตกต่างกันในสองกลุ่ม สรุปผล: colchicine ไม่สามารถลดตัวชี้วัดการเกิดพังผืดในไตหรือทำให้การทำงานของไตดีขึ้นในผู้ป่วยโรคไตเสื่อมเรื้อรัง ส่วนผลต่อการลดการอักเสบยังไม่สามารถสรุปแน่ชัดได้ โดยพบว่า colchicine สามารถลดตัวชี้วัดการอักเสบเรื้อรังในเลือดได้ แต่เพิ่ม urine MCP-1 …

Evaluation Of The Effectiveness Of A Pain Neuroscience Education Curriculum For Patients Who Experience Chronic Musculoskeletal Pain With Concurrent Opioid Dependence, Nicole D. Windsor

Theses and Dissertations--Rehabilitation Sciences

Background: Chronic musculoskeletal pain (CMP) is estimated to affect over 100 million adults annually and is targeted as an instigator of opioid dependence (OpD). Opioid medications are often the first response for patients suffering from CMP, but over 10 million people annually admit to misusing opioids. With the opioid epidemic, the healthcare system now has a population of patients who experience CMP with concurrent OpD. This persistent problem creates a perfect storm of fear of movement, low self-efficacy, and physical dysfunction. A critical component to chronic pain management is understanding how patients view their pain experience. Education may be one …

The Use Of Mechanotherapy To Promote The Recovery From Disuse Atrophy In Aging Rat Skeletal Muscle, Zachary Hettinger

Theses and Dissertations--Rehabilitation Sciences

The combination of age and disuse-related skeletal muscle atrophy predisposes older adults to reduced mobility, loss of independence, and poor quality of life. Poor health outcomes resulting from periods of disuse in older adults are exacerbated by an inability to fully recover, ultimately accelerating geriatric populations towards further functional decline. Aged-related changes to skeletal muscle viscoelastic properties, specifically of muscle extracellular matrix (ECM) stiffness, may not only impact how muscle responds during recovery, but also to interventions intended to augment recovery. Remodeling of muscle ECM in the aged may therefore benefit muscle mass recovery, yet therapies focused on ECM remodeling …

Full Issue, Journal Editors

Yalobusha Review

No abstract provided.

Lonidamine Is A Novel Inhibitor Of Fatty Acid Oxidation, Tianhai He

Theses and Dissertations

In this thesis project, we examined the hypothesis that lonidamine is an effective inhibitor of FAO in mammalian cells, underling its inhibitory effects on bioenergetic production and anti-cancer action. We compared its effects on FAO and glycolysis in multiple human cancer cell lines of different lineages.

Squirreling From Afar: Adapting Squirrel-Net Modules For Remote Teaching And Learning, Laurie Dizney, Johanna Varner, Jennifer Duggan, Hayley C. Lanier, Patrice K. Connors, Liesl P. Erb, Elizabeth A. Flaherty, Christopher J. Yahnke, John D. Hanson

AES Faculty Publications and Presentations

The shift from face-to-face instruction to remote teaching and learning has proven to be a challenging endeavor for many reasons, including lack of time, resources, and inspiration. Lab courses, the “hands-on” portion of many curricula, may be especially difficult to adapt to online learning given the common use of specialized equipment, materials, and techniques that require close supervision. Without the time and resources to creatively modify existing activities or create new ones, remote lab courses run the risk of becoming less effective, equitable, and/or engaging. Squirrel-Net has created four field-based activities for biology labs that are easy to implement, highly …

Implications Of Climate-Driven Fallowing For Ecological Connectivity Of Species At Risk, Sofie He Mccomb, Claire Powers, Forrest Melton, Ashley Larsen

AES Faculty Publications and Presentations

Context.

Climate change and agricultural intensification are modifying the configuration of natural lands within agricultural landscapes, further impacting species’ ability to move freely between remaining natural areas. These working landscapes have inherently high opportunity costs, making the establishment of additional permanent reserves for species movement unlikely.

Objectives.

Here we explore the potential for opportunistic and dynamic conservation reserves, in the form of temporary fallowed croplands, to increase connectivity in competing land use regions.

Methods.

We evaluate the potential for fallowed lands to facilitate habitat connectivity for at-risk species in the San Joaquin Valley (SJV), an intensive agricultural landscape in California. …

Math Leaders’ Perceptions Of Social Justice Pedagogy: Implications For Professional Development On Teaching Mathematics For Climate And Environmental Justice, Angela M. Allen

Theses and Dissertations

Two significant crises facing communities of color are climate and environmental injustices (Schlosberg & Collins, 2014) and the achievement gap in standardized test performance as an impact of inequitable educational experiences rooted in a history of social inequities (Agarwal, 2011; Milner, 2020). Previous studies on teaching mathematics for social justice demonstrate positive student outcomes from this practice (Berry, 2008; Gutstein, 2006). Existing literature also points to benefits when focusing on a specific social justice topic during mathematics instruction (Bartell, 2013; Stocker, 2012). However, few studies focus on math leaders’ perceptions of teaching mathematics for climate and environmental justice (TMCEJ).

This …

A Comprehensive Study To Delineate The Role Of An Extracellular Vesicle-Associated Microrna-29a In Chronic Methamphetamine Use Disorder, Subhash Chand, Austin Gowen, Mason Savine, Dalia Moore, Alexander Clark, Wendy Huynh, Niming Wu, Katherine Odegaard, Lucas Weyrich, Rick A. Bevins, Howard S. Fox, Gurudutt Pendyala, Sowmya V. Yelamanchili

Department of Psychology: Faculty Publications

Extracellular vesicles (EVs), which express a repertoire of cargo molecules (cf. proteins, microRNA, lipids, etc.), have been garnering a prominent role in the modulation of several cellular processes. Here, using both non-human primate and rodent model systems, we provide evidence that brain-derived EV (BDE) miRNA, miR- 29a-3p (mir-29a), is significantly increased during chronic methamphetamine (MA) exposure. Further, miR-29a levels show significant increase both with drug-seeking and reinstatement in a rat MA self-administration model. We also show that EVassociated miR-29a is enriched in EV pool comprising of small EVs and exomeres and further plays a critical role in MA-induced inflammation and …

Prepare For Takeoff: Improving Asset Measurement And Audit Quality With Drone-Enabled Inventory Audit Procedures, Margaret H. Christ, Scott A. Emett, Scott L. Summers, David A. Wood

Faculty Publications

Auditors increasingly employ technologies to improve audit quality. Using a design science approach, we examine whether using drones and automated counting software can improve audit quality and thereby improve financial reporting. We assess three dimensions of audit quality—efficiency, effectiveness, and quality of audit documentation. We provide evidence that auditors can perform inventory counts with these technologies much more efficiently than they can with manual techniques, decreasing count time in our study from 681 hours to 19 hours. At the same time, auditors can maintain or improve audit effectiveness with these technologies, decreasing error rates in our study from 0.15% to …

Corporate Governance And Tax Avoidance: Evidence From Governance Reform, Jon Kerr, Richard Price, Francisco J. Román, Miles A. Romney

Faculty Publications

Prior literature struggles to find evidence in U.S. settings to support the Desai and Dharmapala (2006) theory on how corporate governance affects tax avoidance. Most studies rely on equity incentive compensation as their governance proxy. We use a Mexican setting to examine this association and find firms with stronger governance engage in less tax avoidance. We rely on both a hand-collected governance index and governance reform to show improved corporate governance pushes tax avoidance toward a new equilibrium. Supplementary analyses show associations between governance and tax avoidance are greatest for tax-cost-sensitive familyowned firms and non-cross-listed firms with naturally weaker governance. …

Impacts Of Multiple Environmental Changes On Long‐Term Nitrogen Loading From The Chesapeake Bay Watershed, Shufen Pan, Zihao Bian, Hanqin Tian, Yuanzhi Yao, Raymond G. Najjar, Marjorie A.M. Friedrichs, Eileen E. Hofmann, Rongting Xu, Bowen Zhang

CCPO Publications

Excessive nutrient inputs from land, particularly nitrogen (N), have been found to increase the occurrence of hypoxia and harmful algal blooms in coastal ecosystems. To identify the main contributors of increased N loading and evaluate the efficacy of water pollution control policies, it is essential to quantify and attribute the long‐term changes in riverine N export. Here, we use a state‐of‐the‐art terrestrial–aquatic interface model to examine how multiple environmental factors may have affected N export from the Chesapeake Bay watershed since 1900. These factors include changes in climate, carbon dioxide, land use, and N inputs (i.e., atmospheric N deposition, animal …

Property Transitions, Michael A. Heller

Faculty Scholarship

Time plays a key role in this book. The last two chapters discussed two reasons why time matters to the life of property: over time, owners effect voluntary changes to property in order to carry out their life plans and the state imposes involuntary changes (from the individual owner’s perspective) in response to changing circumstances, shifting needs and wants, and revised public goals. For the state to function – and to remain justified on liberal principles – the government must have this ability to adjust ownership. However, state-initiated transitions to ownership – implemented through governments’ police and takings powers – …

Authoring The Law, Shyamkrishna Balganesh

Faculty Scholarship

Copyright law denies protection to legal texts through a rule known as the “government edicts doctrine”. Entirely a creation of nineteenth century courts, the government edicts doctrine treats expression produced by lawmakers in the exercise of their lawmaking function as altogether uncopyrightable. Despite having been in existence for over a century, the doctrine remains shrouded in significant mystery and complexity. Lacking statutory recognition, the doctrine has come to be seen as driven by open-ended considerations of “public policy” that draw on the overarching importance of public access to laws. In its decision in Georgia v. Public.Resource.Org., Inc., the Supreme …

The African Human Rights System As ‘Norm Leader’: Three Case Studies, Obiora C. Okafor, Godwin E.K. Dzah

Articles & Book Chapters

Africa (including its human rights system) is rarely imagined or considered an originator, agent and purveyor of ideas, including in the human rights sphere. On this occasion of the fortieth anniversary of the adoption of the 1981 African Charter on Human and Peoples’ Rights which founded the African human rights system, it is only fitting that its contributions or otherwise to global human rights praxis, over these four decades, be examined from this perspective. Utilising the theory of the norm life cycle, developed by scholars of international relations who work within ‘strategic social constructivism’, this article examines how the African …

Removing Carbon Dioxide Through Seaweed Cultivation: Legal Challenges And Opportunities, Korey Silverman-Roati, Michael B. Gerrard, Romany M. Webb

Faculty Scholarship

Scientists increasingly agree that carbon dioxide removal will be needed, alongside deep emissions cuts, to stave off the worst impacts of climate change. A wide variety of technologies and strategies have been proposed to remove carbon dioxide from the atmosphere. To date, most research has focused on terrestrial-based approaches, but they often have large land requirements, and may present other risks and challenges. As such, there is growing interest in using the oceans, which have already absorbed more than a quarter of anthropogenic carbon dioxide emissions, and could become an even larger carbon sink in the future.

This paper explores …

Images Of Reach, Range, And Recognition: Thinking About Emotions In The Study Of International Law, Emily Kidd White

Articles & Book Chapters

There is much critical potential in bringing together the philosophy of emotion and the study of international law. Narratives about legitimate political and legal authority have tended to either assume that it is possible to extricate emotions from political judgement, or to rest upon uncomplicated (and wholly demystified) assumptions about the legibility of emotions over time and place. Philosophers interested in emotion have regularly grappled with questions concerning an emotion’s reach and range (insofar that the emotion in question bears an intersubjective component), and recognition (comprehensibility) of emotions beyond one’s own social and political communities (or even beyond one’s self). …

Why Supervise Banks? The Foundations Of The American Monetary Settlement, Lev Menand

Faculty Scholarship

Administrative agencies are generally designed to operate at arm’s length, making rules and adjudicating cases. But the banking agencies are different: they are designed to supervise. They work cooperatively with banks and their remedial powers are so extensive they rarely use them. Oversight proceeds through informal, confidential dialogue.

Today, supervision is under threat: banks oppose it, the banking agencies restrict it, and scholars misconstrue it. Recently, the critique has turned legal. Supervision’s skeptics draw on a uniform, flattened view of administrative law to argue that supervision is inconsistent with norms of due process and transparency. These arguments erode the intellectual …

Introduction To The Edward Elgar Research Handbook On Law And Emotion, Susan A. Bandes, Jody Lynee Madeira, Kathryn D. Temple, Emily Kidd White

Articles & Book Chapters

The role of emotion in law has long been shrouded in mystery. The legal system is built on assumptions about human behavior, including assumptions about emotion. Thus, unavoidably, understanding emotion is an essential part of building a fairer, more effective system. Yet the emergence and growth of Law and Emotion as a field of study has been slowed by the belief that merely by acknowledging emotion, scholars and jurists would undermine the rule of law. It has been further hampered by the suspicion that emotions are too ephemeral or subjective to be understood in any systematic way. For too long, …

Long Live The Common Law Of Copyright!: Georgia V. Public.Resource.Org., Inc. And The Debate Over Judicial Role In Copyright, Shyamkrishna Balganesh

Faculty Scholarship

In Georgia v. Public.Resource.Org, Inc., the Supreme Court resurrected a nineteenth-century copyright doctrine – the government edicts doctrine – and applied it to statutory annotations prepared by a legislative agency. While the substance of the decision has serious impli­cations for due process and the rule of law, the Court’s treatment of the doctrine recognized an invigorated role for courts in the development of copyright law through the use of principled reasoning. In expounding the doctrine, the Court announced a vision for the judicial role in copy­right adjudication that is at odds with the dominant approach under the Copyright …

Presidential Primacy Amidst Democratic Decline, Ashraf Ahmed, Karen M. Tani

Faculty Scholarship

Fifty years ago, when the Harvard Law Review asked Professor Harry Kalven, Jr., to take stock of the Supreme Court’s 1970 Term, Kalven faced a task not unlike Professor Cristina Rodríguez’s. That Term’s Court had two new members, Justices Harry Blackmun and Warren Burger. The Nixon Administration was young, but clearly bent on making its own stamp on American law, including via the Supreme Court. Kalven thus expected to see “dislocations” when he reviewed the Court’s recent handiwork. He reported the opposite. Surveying a Term that included such cases as Palmer v. Thompson, Younger v. Harris, Boddie v. …

A Theory Of Mistaken Assumptions In Contract Law, Jennifer Nadler

Articles & Book Chapters

In Great Peace Shipping v Tsavliris Salvage, the English Court of Appeal rejected the equitable doctrine of mistaken assumptions, arguing that the doctrine lacks a principled foundation. Defenders of the doctrine appear to agree that the doctrine lacks a coherent animating principle, but they think that its open-endedness is an argument in its favour. Against both the critics and the defenders, this article argues that the equitable doctrine of mistaken assumptions is a principled doctrine, one that protects individual self-determination by setting aside a contract that, due to a mistake about the quality of the thing contracted for, serves …

Evolutionary Responses Of Marine Organisms To Urbanized Seascapes, S. Elizabeth Alter, Laraib Tariq, James Keanu Creed, Emmanuel Megafu

Biology, Agriculture and Chemistry Faculty Publications and Presentations

Many of the world's major cities are located in coastal zones, resulting in urban and industrial impacts on adjacent marine ecosystems. These pressures, which include pollutants, sewage, runoff and debris, temperature increases, hardened shorelines/structures, and light and acoustic pollution, have resulted in new evolutionary landscapes for coastal marine organisms. Marine environmental changes influenced by urbanization may create new selective regimes or may influence neutral evolution via impacts on gene flow or partitioning of genetic diversity across seascapes. While some urban selective pressures, such as hardened surfaces, are similar to those experienced by terrestrial species, others, such as oxidative stress, are …

Extracting Indigenous Jurisdiction On Private Land: The Duty To Consult And Indigenous Relations With Place In Canadian Law, Estair Van Wagner

Articles & Book Chapters

Indigenous relations with land are grounded in place-based legal orders which have been regulating the territories now making up Canada for millennia (Borrows 2010, 2018; McGregor 2010). Judicial consideration of Indigenous relations with place has focused on the duty to consult and accommodate with respect to ‘Crown land’ – lands for which federal and provincial governments are the deemed owners. This emphasis on Crown lands is logical – 89 per cent of land in Canada is held by either the federal or provincial Crown (Neimanis 2013). Indigenous claims often expressly exclude private land, wary of courts’ willingness to unsettle third-party …

Do You Copy? Post-Traumatic Stress Disorder, Auditory Processing, And Heart Rate Variability, Lyndsey Johnson

UNF Graduate Theses and Dissertations

Self -report measures used in PTSD research have the potential to limit the degree of symptom severity in military veterans, especially as there is often underreporting in this population (Kline, Falca-Dodson, Susner et al., 2010). Polyvagal Theory provides a framework assessing if physiological measures can tap into PTSD Symptomology (Porges, 1995). It is therefore hypothesized that lower scores on auditory processing tests will be positively correlated with higher scores on Stress and PTSD measures. Additionally, it is thought that lower scores on auditory processing tedts as well as higher scores on PTSD and Stress Measures will be positively correlated with …

Weak Olfactory Preferences Of The Gall Midge Asphondylia Borrichiae, Associated Fungal Endophytes And Implications On Gene Flow And Host Range Expansion, Frances S. Nagle

UNF Graduate Theses and Dissertations

Asphondylia borrichaie is a small fly (Diptera: Cecidomyiidae) that is currently undergoing host-associated sympatric divergence. Asphondylia borrichaie is an ambrosia galler, these insects utilize a host plant for oviposition, but its offspring also rely on a symbiotic fungus (or fungal community) to promote the formation of the gall as well as serve as a food source for the developing larvae. Previous studies indicate that A. borrichaie consists of two host- associated populations based on its original host plant Borrichia frutescens (Asterales: Asteraceae), and another one from the two Iva species (I. frutescens (Asterales: Asteraceae) and I. imbricata …

Inside The Zoo: Captive Giraffes’ Changes In Social Ties Throughout Membership Variations, Morgan Paige Howard

UNF Graduate Theses and Dissertations

Many animals live in gregarious, fission-fusion societies where group size and composition are continually changing. Despite this, many studies have suggested that captive animals are capable of maintaining long term social bonds with others. In captive giraffes, effects on their social bonds during membership transitions have not been studied thoroughly, however, prior research does show that social bonds are a defining factor in non-captive animals. Captive giraffe social network patterns were investigated at the Jacksonville Zoo and Botanical Gardens using all occurrence behavioral data. Based on previous research, I hypothesized that when one of the individuals in the group was …

An Assessment Study Of Student Experiences In A University Conduct Process, Lucas Jay Morrill

UNF Graduate Theses and Dissertations

This study implements a quantitative assessment survey to explore how experiences of students who participated in a conduct hearing process during the 2020 fall academic semester align with the conduct process learning outcomes of a private liberal arts institution located in northeast Florida (Northeast University). Survey descriptive statistics indicate Northeast University’s conduct process facilitated student understanding of university policies, understanding of their impact on the campus community, and facilitated a process that resulted in a student’s intention to no longer violate university policy again in the future. Data collected also presents trends for students held responsible for COVID-19 related policy …

Lipid Markers And Compound-Specific Carbon Isotopes As Diet And Biosynthesis Reflectors In The Northern Neptune Whelk Neptunea Heros, H. Rodger Harvey, Rachel Mcmahon, Karen A. Taylor

OES Faculty Publications

A suite of lipid biomarkers plus compound-specific carbon isotopes of major sterols were determined in muscle tissues across increasing sizes of northern Neptune whelks Neptunea heros, developing eggs and potential diets to link trophic patterns, metabolism and carbon sources on the Chukchi Sea shelf. Analysis of primary prey included the northern clam Astarte borealis, water column particulate organic matter (POM) and surface sediments near the collection sites. Sterols specific to major algal groups along with algal-derived polyunsaturated fatty acids (C20:5n-3, C20:4n-3, C22:6n-3) in whelk muscle tissue reflected the importance of algal primary production to benthic consumers and its …