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The Wealth Of Nations V.2, Adam Smith

Hannah Arendt Marginalia - All

London: Dent; New York: Dutton, 1950, 1910

Contains marginalia, underlining and marginal lining.

Call #: HB161 .S64 1950

PDF Information: 18 pages – 13.3mb

Disunion And Convict Labor Along The Gulf Coast Pine Belt, 1870-1930, Brianna Harrison

Electronic Theses and Dissertations Archive

This project examines lumber and naval stores workers from the late nineteenth and early twentieth centuries along the Gulf Coast of Louisiana, Mississippi, Alabama, and Florida. After the Civil War, lumbermen who had exhausted the timber supply in the North and Midwest looked to the South’s pine forests as the national demand for lumber and lumber products increased. The creation of the lumber and naval stores industries along the Gulf Coast pine belt, however, coincided with labor abuses, including the convict lease system and debt peonage. Moreover, company owners and management structured the industries in a way that perpetuated the …

Chemically Mediated Communication In Mound-Building Termites, Sree Subha Ramaswamy

Theses and Dissertations

Nest-building in social insects requires layered communication to coordinate complex, functional structures for housing, protection, storage, and homeostasis. This is especially striking in mound-building termites, which construct and repair large mounds collectively despite lacking image-forming eyes. This thesis investigates how Odontotermes obesus achieves such coordination through chemical communication embedded in soil.

Using controlled two-choice assays with manipulated soils, I separated airborne volatile signals from contact non-volatile signals by baking to remove volatiles, a mesh assay that presented volatile cues without contact, and solvent extraction with reapplication of contact cues. I quantified responses in major-only, minor-only, and mixed groups at two …

Impact Of Urban Fine Particulate Matter Exposure On Cardiovascular Health, Shelby P. Briggs

Honors Theses

Air pollution, particularly exposure to fine particulate matter (PM2.5), poses a growing threat to cardiopulmonary health. PM2.5 consists of microscopic particles smaller than 2.5 microns in diameter and originates from industrial combustion, transportation, and urban dust. These particles are classified as xenobiotics and are capable of bypassing respiratory defenses to enter systemic circulation, where they cause oxidative stress, inflammation, and cardiovascular dysfunction. This study examines the effects of PM2.5 on cardiovascular function using a murine model. Male C57BL/6 mice were divided into control (saline), subchronic (10 µg), and chronic (100 µg) groups and were exposed weekly for 11 weeks via …

Nestview-Transforming House Hunting With Ar, Chia-An Lee

Theses

NestView is an augmented reality (AR) based smart glasses system which aims to facilitate the process of finding rental homes for people. Conventional rental websites bombard users with two-dimensional data and have no sense of place, which is why they're both time-consuming and mentally taxing. NestView gives the user real-time mobile listings displayed in AR right in their physical space, providing an immersive, contextually aware rental experience. Informed by a user-centered design methodology, this study examines what frustrations the renters experience, and in what ways AR applications can meet those frustrations. The system comes with proximity-driven filtering, voice interactions, an …

Successful Artificial Incubation And Juvenile-Rearing Of Dropped Eggs Of A Critically Endangered Freshwater Crayfish (Cherax Tenuimanus), Rodney Duffy Dr., Blaine Hodgson, Amber Quinn, Marcus Newman

Fisheries Research Articles

One-third of the world’s freshwater crayfish species face extinction risk, necessitating extreme and urgent conservation measures such as captive rearing. Little information exists on these measures for most threatened species. The hairy marron, Cherax tenuimanus (Parastacidae), is a critically endangered freshwater crayfish endemic to the Margaret River in south-western Western Australia. C. tenuimanus is being rapidly replaced by the smooth marron, Cherax cainii, a translocated congener, causing its progressive decline in range, and now it faces imminent extinction in the wild. Attempts at captive breeding have resulted in few occurrences of egg laying of C. tenuimanus, which ended in complete …

Hippocampal Avoidance During Prophylactic Cranial Irradiation For Patients With Small Cell Lung Cancer: Randomized Phase Ii/Iii Trial Nrg-Cc003, Vinai Gondi, Stephanie L Pugh, Minesh P Mehta, Jeffrey S Wefel, Wolfgang A Tomé, Alexander Y Sun, John Grecula, Kristin J Redmond, Shannon Fogh, Laurie Gaspar, Andre Konski, Joseph Bovi, Clifford G Robinson, Benjamin Corn, Gregory M Videtic, Benjamin H Lok, Harold A Yoon, John H Heinzerling, Albert S Denittis, Ronald C Mcgarry, Kiran Devisetty, Vijayananda Kundapur, Abraham J Wu, Edward C Mccarron, Isabelle Thibault, Edmund L Simon, Andrew M Baschnagel, Samir Narayan, Jondavid Pollock, Rebecca Paulus, Lisa A Kachnic

Faculty, Staff and Student Publications

Purpose: Hippocampal avoidance (HA) during therapeutic whole-brain radiotherapy reduces the risk of neurocognitive function (NCF) toxicity in patients with brain metastasis. This trial hypothesized that HA during prophylactic cranial irradiation (PCI) in patients with small cell lung cancer (SCLC) leads to noninferior intracranial relapse (ICR) and reduction in NCF toxicity.

Methods: This randomized phase II/III trial enrolled patients with SCLC, no brain metastases, and response to chemotherapy. The primary end points were 12-month ICR (noninferiority design, randomized phase II) and 6-month Hopkins Verbal Learning Test-Revised (HVLT-R) Delayed Recall (DR) failure (phase III). Secondary end points were failure in any NCF …

Keap1 And Stk11/Lkb1 Alterations Enhance Vulnerability To Atr Inhibition In Kras Mutant Non-Small Cell Lung Cancer, Ana Galan-Cobo, Natalie I Vokes, Yu Qian, David Molkentine, Kavya Ramkumar, Alvaro G Paula, Marlese Pisegna, Daniel J Mcgrail, Alissa Poteete, Sungnam Cho, Minh Truong Do, Amirali Karimi, Yifan Kong, Anisha Solanki, Ankur Karmokar, Nicolas Floc'h, Adina Hughes, Rebecca Sargeant, Lucy Young, Li Shen, Gozde Kar, Caezaan Keshvani, Claudio Arrechedera, Sharia Hernandez, Katharina Schlacher, Jing Wang, Sonia Iyer, James Conway, Mohamed Reda Keddar, Marta Milo, Ilario De Toma, Susan E Critchlow, J Carl Barrett, Jan Cosaert, Alan Lau, Viia Valge-Archer, Lauren A Byers, Simon T Barry, John V Heymach

Faculty, Staff and Student Publications

KRAS mutations frequently co-occur with alterations in STK11/LKB1 and/or KEAP1, defining an aggressive subset of lung cancers resistant to immuno- and chemotherapy. While LKB1 loss is associated with vulnerability to DNA damage response-based therapies, the impact of KEAP1 alterations remains unknown. We demonstrate that KEAP1-NRF2 pathway drives a compensatory modulation of ATR-CHK1 signaling, enhancing vulnerability to ATR inhibitors (ATRi), particularly in the setting of increased replication stress associated with LKB1 loss. ATRi shows enhanced anti-tumor activity in LKB1 and/or KEAP1-deficient non-small cell lung cancer (NSCLC) models and synergizes with gemcitabine. ATRi also enhances antitumor immunity and mitigates the immunosuppressed phenotype …

Agricultural Biotechnology In The Courts: Judicial Opinions And Commentary, Drew L. Kershen

Faculty Articles

Seven jurisdictions from around the world have issued judicial opinions that address fundamental issues about the governance and regulatory systems of agricultural biotechnology. This article summarizes these legal proceedings and describes their impact upon agricultural biotechnology. The article then provides a commentary and critique of the legal proceedings and resulting judicial opinions.

Core Outcome Set And Measures Of Chest Health In Children And Young People With Cerebral Palsy In The Community Setting: The Chesti Study Protocol, Chesti-Study Steering Group, Rachel Knight Lozano, Christopher Morris, Harriet Shannon, Kayleigh Bell, Hugh Malyon, Julia Melluish, Jos Latour, Morag Andrews, Sarah Crombie, Noula Gibson, Samantha Grace, Sian Goddard, Nicola Harman, Sarah Mc Goldrick Kolawole, Laura Lowndes, Paul Mcnamara, Madeline Pilbury, Rachel Rapson, Nicola Scivier, Diane Sellers, Caroline Weighton, Mark Williams, Luana Winston

School of Health Professions

Introduction Poor chest health is the leading cause of early mortality in children with cerebral palsy (CP). It is also the most common reason to seek healthcare, accruing significant costs and reducing quality-of-life for children and families. Clinical trials examining chest health interventions in CP are characterised by inconsistent outcome measures, limiting the capacity for evidence synthesis to inform clinical application. The study aims to develop a core outcome set (COS) and related measurement instruments to assess, monitor and evaluate chest health in children with CP, both in research and routine clinical practice. The COS will reflect the views of …

Effect Of Potassium Fertilizer On The Nutrition And Physical Quality Of Job’S Tears (Coix Lacryma-Jobi L.) Seeds, Qinthara Nail Haysa, Yuyun Yuwariah, Fiky Yulianto Wicaksono

Jurnal Kultivasi

Job's tears is a cereal crop that has beneficial nutrients. Potassium is known to affect the growth and yield of cereal crops, but there has been limited study on whether potassium affects the nutrition and physical quality of Job’s tears seeds. This study aimed to analyze the effect of K fertilizer on the nutritional content and physical quality of Job's tears seeds. This research was conducted from January to May 2024 at Ciparanje Experimental Field, Faculty of Agriculture, Universitas Padjadjaran, Sumedang, Indonesia. This experiment used the Randomized Block Design (RBD) method with six treatments and four replications. Various doses of …

The Interplay Of Oxidative Stress, Mitochondrial Dysfunction, And Neuroinflammation In Autism Spectrum Disorder: Behavioral Implications And Therapeutic Strategies, Ansab Akhtar, S K. Rahaman

School of Medicine Faculty Publications

Autism spectrum disorder (ASD) deals with several symptoms, including language and speech impairment and developmental delays. The main brain regions affected could be the prefrontal cortex (PFC) or the temporal lobe. The detrimental features could include oxidative stress, mitochondrial dysfunction, and neuroinflammation. Most often, these phenomena are interrelated and can lead to one another, creating a vicious cycle. They also influence the regulation of certain genes involved in the pathogenesis of ASD or related behavior. In the brain regions prone to these detrimental features, a cascade of free radicals, inflammatory cytokines, and mitochondrial energy disruptions is initiated. These actions during …

Promoting Mitochondrial Fusion Is Protective Against Cancer-Induced Muscle Detriments In Males And Females, Francielly F. Morena, Seongkyun Lim, Ana Regina Cabrera, Toby L. Chambers, Pieter J. Koopmans, Stavroula Tsitanou, Sabin Khadgi, Calvin Peterson, Eleanor R. Schrems, Ruqaiza Muhyudin, Sepideh Shakeri, Kevin Zhao, Devan Mishra, Tyrone A. Washington, Kevin A. Murach, Nicholas P. Greene

Health, Human Performance and Recreation Faculty Publications and Presentations

Background Skeletal muscle atrophy during cancer-induced cachexia remains a significant challenge in cancer management. Mitochondrial defects precede muscle mass and functional losses in models of cancer cachexia (CC). We hypothesized targeting Opa1-a key regulator of mitochondrial fusion-can attenuate LLC-induced CC outcomes.

Methods We utilized 1) in vivo transgenic Opa1 overexpression (OPA1 TG) in LLC-induced CC in vivo, and 2) BPG15 administration to induce Opa1 in vitro and in vivo.

Results OPA1 TG attenuated plantaris, gastrocnemius, and EDL loss with LLC in males and alleviated gastrocnemius loss infemales. OPA1 TG had greater mitochondrial respiration in plantaris and white gastrocnemius, and lowered …

It Shucks To Be Inbred: Effects Of Small Population Sizes On Genomic Diversity Of Hatchery Reared Olympia Oysters (Ostrea Lurida), Anna S. Heasley

Master's Theses

Olympia oysters (Ostrea lurida), critical members of estuarine ecosystems along the California Current Ecosystem (CCE), have faced significant population declines due to historical overfishing and habitat deterioration. Today, managers from multiple estuaries across the CCE are focusing on conservation aquaculture breeding efforts to aid in restoration; however, the genetic implications of these efforts remain unexplored. As with other Ostrea spp, Olympia oysters have a viviparous reproductive strategy that creates unique challenges for aquaculture-mediated restoration. This study evaluates the genetic impact of current captive breeding practices on Olympia oyster cohorts produced in three California estuaries: Elkhorn Slough (EHS), Morro Bay (MB), …

Polo-Like Kinase 1 Inactivation Enhances Pi3k Inhibition-Mediated Apoptosis Of Notch1-Mutant Head And Neck Squamous Cell Carcinoma, Pooja A Shah, Tuhina Mazumdar, Soma Ghosh, Lacin Yapindi, Reid T Powell, Yong S Park, Li Shen, Anne M Fernandez, Clifford C Stephan, Jing Wang, Andrew G Sikora, Jawad Kazi, Mitchell J Frederick, Faye M Johnson

Children’s Nutrition Research Center Staff Publications

PI3K inhibition causes apoptosis selectively in NOTCH1-mutant head and neck squamous cell carcinoma (HNSCC), but modest single-agent responses and acquired resistance (AR) limit the clinical efficacy of targeted agents. To address these limitations, we investigated novel combination therapies. We tested the efficacy of 5768 compounds as single agents and 139 in combination with PI3K inhibitors in sensitive and AR NOTCH1-mutant HNSCC cell lines. We generated synergy/efficacy classifications for the combinations using multiple metrics of statistical drug synergy and growth rate indices. The PLK1/PI3K combination's efficacy was validated using orthogonal in vitro methods and in two HNSCC xenograft models. Compound efficacy …

Mutant P53 Confers Chemoresistance By Activating Kmt5b-Mediated Dna Repair Pathway In Nasopharyngeal Carcinoma, Haidan Luo, Mo-Fan Huang, An Xu, Donghui Wang, Julian A Gingold, Jian Tu, Ruoyu Wang, Zijun Huo, Yen-Ting Chiang, Kuang-Lei Tsai, Jie Su, Danielle A Bazer, Mien-Chie Hung, Canmao Xie, Yubiao Guo, Dung-Fang Lee, Huiling Yang, Ruiying Zhao

Faculty, Staff and Student Publications

Nasopharyngeal carcinoma (NPC), a malignancy arising from the nasopharyngeal epithelium, is common in the east and southeast area of Asia. Treatments for locally advanced and recurrent NPC include chemotherapy (usually combined with 5-Fluorouracil, 5-FU) and radiotherapy, but response is limited due to chemo-resistance. p53 mutation is a critical factor for 5-FU resistance in some cancers, but its role in NPC chemo-resistance remains unclear. Here, we demonstrate that p53(R280T), a common p53 somatic mutation found in multiple NPC tumor samples, induces gain-of-function upregulation of DNA repair genes which leads to 5-FU resistance in NPC. p53(R280T) specifically upregulates the expression of DNA …

Paradoxical Forms Of Scientific Heroism When Responsibly Conducting Research, Theresa A. Thorkildsen

Heroism Science

The Stanford Prison Experiment is widely known for offering insight into the responsible conduct of research as well as how prisoners and prison guards fall easily into potentially harmful roles. As the principal investigator of the study, Philip Zimbardo became a polarizing figure in the social sciences -- both celebrated as a pioneering hero and criticized for ethical shortcomings -- while consistently engaging with his critics throughout his career (Zimbardo, n.d.). Highlighting Zimbardo’s influence on the protection of human research participants, this article uses details from Zimbardo’s self-reflections and insights on the paradoxes of heroism to convey how research personalities …

Proceedings Of The 2025 Undergraduate Research Day, Rebecca Day Babcock Dr., Mohamed Zobaa

UTPB Student Research Day 2026

No abstract provided.

Vaccination With Acinetobacter Baumannii Adhesin Abp2d Provides Protection Against Catheter-Associated Urinary Tract Infection, Morgan R Timm, Kevin O Tamadonfar, Taylor M Nye, Jesús Bazán Villicaña, Jerome S Pinkner, Karen W Dodson, Ali H Ellebedy, Scott J Hultgren

2020-Current year OA Pubs

Catheter-associated urinary tract infections (CAUTIs) contribute greatly to the burden of healthcare-associated infections. Acinetobacter baumannii is a Gram-negative bacterium with high levels of antibiotic resistance that is of increasing concern as a CAUTI pathogen. A. baumannii expresses fibrinogen-binding adhesins (Abp1D and Abp2D) that mediate biofilm formation on catheters, which become coated with fibrinogen upon insertion. Here we develop a protein subunit vaccine against the Abp1D and Abp2D receptor binding domains (RBD) and show that vaccination significantly reduces bacterial titers in a female mouse model of CAUTI. We further demonstrate that immunity to Abp2D

Impact Of A Multi-Strain L. Crispatus-Based Vaginal Synbiotic On The Vaginal Microbiome: A Randomized Placebo-Controlled Trial, Jacques Ravel, Sheri Simmons, Eleni Greenwood Jaswa, Sara Gottfried, Miriam Greene, Susan Kellogg-Spadt, Dirk Gevers, Diane M. Harper

Institute of Emerging Health Professions Faculty Papers

A clinical trial of a multi-strain vaginal synbiotic (NCT05659745, registered 12/19/2022 at clinicaltrials.gov) led to an optimal vaginal microbiome dominated by L. crispatus (CST I). The synbiotic led to a significant increase in L. crispatus compared to placebo (p <  0.05), and conversion to CST I was significantly higher with the vaginal synbiotic than with placebo (90 vs 11%; p <  0.002). Mechanistically, the synbiotic reduced Gardnerella vaginalis and Candida, clinically important microbes.

Enhancing Target Dose Conformity While Effectively Sparing The Spinal Cord In Proton Arc Treatment Plans For Cervical Chordomas And Chondrosarcomas, Jon Blalock

Masters Projects

Cervical spinal chordomas and chondrosarcomas present significant therapeutic challenges due to their proximity to the spinal cord and resistance to conventional radiotherapy. This retrospective study investigated the capability of proton arc therapy (PAT) to maintain or improve adequate target coverage while reducing dose to the spinal cord for cervical spinal chordomas and chondrosarcomas over standard fixed beam intensity modulated proton therapy (IMPT). While both IMPT and PAT use pencil beam scanning (PBS) to with energy modulation to deliver dose in discrete layers, IMPT relies on a limited number of fixed beam angles, whereas PAT delivers dose over an arc trajectory. …

Between Shelter & Ash, Designing Fire-Proof Resilient Neighborhoods, Arlene I. Garcia Guzman

McNair Summer Research Program

In response to the ongoing catastrophic wildfires in the U.S., especially the West Coast region, the State of California is proactively implementing the first multi-faceted legislative and regulatory framework to enhance wildfire resiliency.

During a disaster, embers are the most important contributors to wildfire, and can dictate whether homes ignite or not. Given their potent ignition source, their capacity to travel for miles, researchers have concluded that wind-blown embers are the leading cause of destruction during wildfires. Simultaneously, the purpose of the 2025 building codes is to strengthen construction methods, requiring the use of rated structural materials, such as sheathing, …

Environmental Citizenship And Behavioral Determinants Of Wind Farm Tourism: Evidence From Grass Skyline, Zhangjiakou, China, Danqing Liu, Leonardo Jackson, Randall S. Upchurch, Catherine Johnson

Plymouth Business School

This study examines the intersection of renewable energy and tourism by exploring why domestic tourists visit wind farm sites for recreation. Traditionally seen as industrial facilities, wind farms are now recognized as dual-purpose attractions that promote environmental awareness and local economic growth. Using the Value–Belief–Norm (VBN) theory, Theory of Planned Behavior (TPB), and New Environmental Paradigm (NEP) as theoretical lenses, we investigate the psychological, social, and cultural factors influencing wind farm tourism. The key determinants of tourist behavior include attitudes, subjective norms, perceived behavioral control, personal norms, and environmental beliefs. Structural equation modeling (SEM) indicates that personal norms have the …

The Tabernacle Hermeneutic: Mosaic Permission From Ex 25:40 To Behold Christ, Christopher G. Miller

Liberty Theological Review

Ex 25:40 is a hermeneutic used by Moses which gives the reader permission to behold Christ and “heavenly things” (τῶν ἐπουρανίων) in the tabernacle instructions (Ex 25-40). This Mosaic hermeneutic is highlighted by the author of Hebrews (Heb 8:5). The overwhelming textual and thematic connections between the tabernacle instructions and the creation account (Gen 1-3) demonstrates that this tabernacle hermeneutic (Ex 25:40) may be useful in other contexts in the Pentateuch. This tabernacle hermeneutic should be used on passages that share words, plot, and ceremonial practices with the tabernacle instructions. The use of “horn” (qeren) is analyzed in each major …

The Problem Of Selective Miracles, Andrew Hronich

Liberty Theological Review

The problem of evil designates an umbrella of similarly related arguments linked together by family characteristics. Within this larger genus, the problem of selective miracles stands apart as a particularly underdeveloped species of argument that analytical and philosophical theologians have failed to adequately reckon with. By contextualizing this peculiar argument within an adequate metaethical framework, this article synthesizes a deontological framework with the elucidating work of John Peckham and his cosmic warfare theodicy. It further repudiates alternative approaches to the problem of selective miracles proffered by consequentialists and process theologians. In sum, the article contends that Peckham's cosmic warfare theodicy …

Subject Index, 13 Months Ended January 1978, American Institute Of Certified Public Accountants

Tax Adviser

No abstract provided.

Building Climate Resilience: Community Gardens And Environmental Education In Christchurch, New Zealand, Caleb T. Mccauley

Capstone Collection

The socio-political movements in post-earthquake Christchurch are studied to better understand the interplay of community gardens, climate, environmental, and land-based education, and to analyze their relevance to entrenching climate resilience in the region. Social networks and community responses to natural disasters like an earthquake are leveraged to understand their ability to influence the pillars of climate resilience, those being community, economic, and ecological resilience, respectively. The central hypothesis and research question of this paper will seek to answer: Can social cooperation in the wake of a natural disaster influence the ability of a community to respond to similar disruptions caused …

Shimmering Mirage Or A Promised Land? Climate Change, Agriculture, And Internal Migration In Sabha, Jordan, Tyler J. Rak

Capstone Collection

Given the rapidly shifting climate, high vulnerability, and low adaptability to climate related changes that rural areas face, this study highlights the complex relationship between climate change -- especially water scarcity -- agriculture, and internal migration in rural Jordan. I predict that if water scarcity is present and climate changes are occurring, they will undercut the rural agriculture sector which could contribute to rural out-migration. To study this relationship, I conducted a case study in Sabha, a small rural community in the Northern Badia of Jordan. Data was gathered by engaging in semi-structured interviews with current community members in Sabha …

Textile Work And Its Interface With Climate Change For Quechua Communities In Peru, Esmeralda Torres-Martinez

Capstone Collection

English – Indigenous communities have argued that their knowledge, lived experiences, and representation are crucial to address the climate transition because their communities have adapted to past climatic changes. Although climate change and culture can be interconnected in ways that are unique to each community, little research is done on how cultural practices can be catalysts for climate action. In fact, communities around the world have sparked socio-political movements from within their cultural context to solve both local and global issues. Therefore, this research asks how the practice of traditional textile making and weaving assist Quechua communities with adapting to …

From Larvae To Livelihoods: Examining The Realities Of Black Soldier Fly Farming In Malawi, Emily Herriott

Capstone Collection

Black Soldier Fly (BSF) larvae offer a cost-effective, nutrient-rich alternative to synthetic fertilizers and conventional feed inputs such as soy, fishmeal, and maize bran in sub-Saharan Africa. In Malawi, where smallholder farmers grapple with declining soil fertility, high input prices, chronic food insecurity, and livestock nutritional challenges, BSF farming is emerging as a promising circular agricultural innovation. Despite its technical promise, the social, economic, and ecological realities of BSF adoption remain underexplored.This study investigates the early implementation of BSF farming in Malawi through the Sustainable Livelihoods Framework, focusing on farmer experiences, challenges, and the social and structural processes shaping uptake …