Digital Commons Network^™

Standing In Solidarity, Marching For More, Lauren Durham

Materials from the University of Dayton Magazine Website

Students organized a march and rally to demonstrate and affirm the dignity of every person.

Aberrant Recruitment Of Leukocytes Defines Poor Wound Healing In Patients With Recessive Dystrophic Epidermolysis Bullosa., Taylor Phillips, Leonie Huitema, Rodrigo Cepeda, Diego De Los Cobos, Regina Isabella Matus Perez, Mauricio Salas Garza, Franziska Ringpfeil, Bahar Dasgeb, Jouni Uitto, Julio Cesar Salas-Alanis, Vitali Alexeev, Olga Igoucheva

Department of Dermatology and Cutaneous Biology Faculty Papers

BACKGROUND: Poorly healing wounds are one of the major complications in patients suffering from recessive dystrophic epidermolysis bullosa (RDEB). At present, there are no effective means to analyze changes in cellular and molecular networks occurring during RDEB wound progression to predict wound outcome and design betted wound management approaches.

OBJECTIVES: To better define mechanisms influencing RDEB wound progression by evaluating changes in molecular and cellular networks.

METHODS: We developed a non-invasive approach for sampling and analysis of wound-associated constituents using wound-covering bandages. Cellular and molecular components from seventy-six samples collected from early, established and chronic RDEB wounds were evaluated by …

Content Modelling For Unbiased Information Analysis, Milind Gayakwad, Suhas Patil Dr

Library Philosophy and Practice (e-journal)

Content is the form through which the information is conveyed as per the requirement of user. A volume of content is huge and expected to grow exponentially hence classification of useful data and not useful data is a very tedious task. Interface between content and user is Search engine. Therefore, the contents are designed considering search engine's perspective. Content designed by the organization, utilizes user’s data for promoting their products and services. This is done mostly using inorganic ways utilized to influence the quality measures of a content, this may mislead the information. There is no correct mechanism available to …

Determination Of The Δ 2 H Values Of High Molecular Weight Lipids By High Temperature Gc Coupled To Isotope Ratio Mass Spectrometry, Sk Lengger, Y Weber, Kwr Taylor, Sh Kopf, Et Al

School of Geography, Earth and Environmental Sciences

Rationale The hydrogen isotopic composition of lipids (d2Hlipid) is widely used in food science and as a proxy for past hydrological conditions. Determining the d2H values of large, well-preserved triacylglycerides and other microbial lipids, such as glycerol dialkyl glycerol tetraether (GDGT) lipids, is thus of widespread interest but has so far not been possible due to their low volatility which prohibits analysis by traditional gas chromatography/pyrolysis/isotope ratio mass spectrometry (GC/P/IRMS). Methods We determined the d2H values of large, polar molecules and applied high-temperature gas chromatography (HTGC) methods on a modified GC/P/IRMS system. The system used a high-temperature 7-m GC column, …

Characterization Of The 5′-Flanking Region Of The Human And Mouse Chac1 Genes, Yuki Nomura, Charity F. Sylvester, Lisa O. Nguyen, Mahmoud Kandeel, Yoko Hirata, Imran N. Mungrue, Kentaro Oh-Hashi

School of Medicine Faculty Publications

The Unfolded Protein Response pathway is a conserved signaling mechanism having important roles in cellular physiology and is perturbed accompanying disease. We previously identified the novel UPR target gene CHAC1, a direct target of ATF4, downstream of PERK-EIF2A and activated by the UPR pathway. CHAC1 enzyme directs catalysis of γ-linked glutamate bonds within specific molecular targets. CHAC1 is the first enzyme characterized that can catalyze intracellular glutathione degradation in eukaryotes, having implications for regulation of oxidative stress. DDIT3 (CHOP) is a terminal UPR transcription factor, regulated by ATF4 and an output promoting cell death signaling. Herein we examine the relationship …

Reviews, Various Authors

Marvels & Tales

No abstract provided.

Affirmative Action And Mismatch: Evidence From Statewide Affirmative Action Bans, Leon Ren

Undergraduate Economic Review

This paper empirically evaluates the mismatch hypothesis by exploiting the quasi-experimental variation in the adoption of statewide affirmative action bans. Specifically, this paper examines the effect of such bans on minority graduation rates using a difference-in-difference, synthetic control, and triple-difference approach. My results suggest that statewide affirmative action bans are associated with an increase in minority graduation rates, consistent with the mismatch hypothesis, at highly selective institutions. Moreover, mismatch effects are not confined to science, technology, engineering, and math (STEM) majors. JEL Codes: I28, J15

Built-In @ Booth: Dei As A Library Priority, Kirstin Duffin, Stacey Knight-Davis, Beth Heldebrandt, Zach Newell

Together We RISE (Making Excellence Inclusive)

Booth Library has been working as a cross-disciplinary partner to facilitate critical conversations and has been acting as an ally in advancing diversity, equity and inclusion initiatives. Booth has also prioritized its work with DEI by recently completing a strategic plan. One of the main goals of the strategic plan is to build in and sustain DEI initiatives as part of a holistic effort to ally Booth with campus and community partners in advancing this goal. The presenters will discuss how Booth has been positioned as a model and hub for promoting DEI on campus. Among the initiatives to be …

Level Up On Diversity, Inclusion And Equity, Jack Blahnik

Together We RISE (Making Excellence Inclusive)

This presentation will detail practices and procedures faculty and staff can take in a virtual environment to be more equitable, inclusive and diverse minded. Now more than ever, it is integral to not only advocate for our underserved student populations, but actively support and engage these students in practices that equitable and inclusive for all. Now more than ever, it is vital that institutions across the US recognize the injustices that often plaque our communities of color and underserved populations; thus, it is critical that faculty and staff make a conscious and intentional effort to do better. As the people …

Il-1 Inhibitor Anakinra Is An Effective Alternative To Standard Treatments For Reducing Pain Due To Acute Gout Flare, Cheryl Craig

Clinical Research in Practice: The Journal of Team Hippocrates

A clinical decision report appraising Janssen CA, Voshaar MAHO, Vonkeman HE, et al. Anakinra for the treatment of acute gout flares: a randomized, double-blind, placebo-controlled, active-comparator, non-inferiority trial. Rheumatology. 2019;58(8):1344-1352. https://doi.org/10.1093/rheumatology/key402 for a patient with an acute gouty attack refractory to standard treatment.

Cyclosporine Shows Benefit As Compared To Methotrexate For Treatment Of Pediatric Atopic Dermatitis Refractory To Topical Medications When Rapidity Of Clinical Response Is Of Key Importance To The Patient, Connor R. Buechler, Steven Daveluy Md

Clinical Research in Practice: The Journal of Team Hippocrates

A clinical decision report appraising El-Khalawany MA, Hassan H, Shaaban D, Ghonaim N, Eassa B. Methotrexate versus cyclosporine in the treatment of severe atopic dermatitis in children: a multicenter experience from Egypt. European Journal of Pediatrics. 2012;172(3):351-356. https://doi.org10.1007/s00431-012-1893-3 for a pediatric patient with severe atopic dermatitis.

Little Is Known About Cannabidiol For Improving Severe Behavioral Symptoms Of Autistic Spectrum Disorder, Keerteshwrya Mishra

Clinical Research in Practice: The Journal of Team Hippocrates

A clinical decision report appraising Barchel D, Stolar O, De-Haan T, et al. Oral cannabidiol use in children with autism spectrum disorder to treat related symptoms and co-morbidities. Frontiers in Pharmacology. 2019;9. https://doi.org/10.3389/fphar.2018.01521

Incorporating Brain-Based Learning Into Virtual Career Support And Delivery, Angela Evans, Hannah Nicolaisen, Mildred Wallace

Together We RISE (Making Excellence Inclusive)

Career development is a life-long, continuous process with many complex factors and interplay. This is also reflected in what makes up the learner of today and the demands of the current pandemic on flexible learning styles and modes of delivery to prepare for success. An eclectic toolbox is needed to meet and adapt to one’s unique strengths, needs, abilities, and preferences via different modes of communication. A purposeful and enhanced focus on experiential learning strategies may be achieved by using pseudo-flipped career training and brain-based learning. Some tenets include emotional intelligence, cognitive behavior therapy, and stages of readiness which may …

The Nexstem Program: A Community Assets Program That Fosters The Next Generation Of Stem Leaders, Maggie Evans, Sheri L. Glowinski, Pennie Gray, Rebecca Roesner

Together We RISE (Making Excellence Inclusive)

Underrepresentation in science, technology, engineering, and mathematics (STEM) fields by individuals with low socioeconomic status (SES) is a long-standing concern. Funded in late 2018, the NexSTEM Program (the “Program”) is a National Science Foundation multi-institution consortia S-STEM grant-funded program at Illinois Wesleyan University (IWU), Illinois State University (ISU), and Heartland Community College (HCC) with the goal of reducing barriers for low SES students from Central Illinois enrolling in and completing STEM degree programs at the three institutions and identifying effective, and sustainable, programmatic components. To help address barriers, the Program awards 2- and 4-year scholarships to academically successful students with …

Changing Guidelines: Recommendation Of Early Peanut Introduction For Prevention Of Peanut Allergy In Infants With Severe Eczema, Alexandra H. Zetye

Clinical Research in Practice: The Journal of Team Hippocrates

A clinical decision report appraising Du Toit G, Roberts G, Sayre PH, et al. Randomized trial of peanut consumption in infants at risk for peanut allergy. New Eng J Med. 2015;372(9):803-813. https://doi.org/10.1056/nejmoa1414850

Assessing Motivation And Utilizing Motivational Interviewing In Introductory College Biology For Improved Student Success, William Martin

Together We RISE (Making Excellence Inclusive)

Student motivation, metacognition and engagement are strong predictors of academic success in the undergraduate biology classroom. Implementation of diverse active learning strategies results in increased student engagement and improved student performance. Instructors direct students on behaviors aimed to promote self-reflection and self-efficacy towards academic success yet see varying follow-through from students. This research study assesses motivation in students in two separate but parallel, introductory biology courses required for majors. Students in one course, with traditionally high attrition and serving students from diverse majors, will be compared to a second with low historical attrition and serving a single pre-professional program at …

2020 12th Annual Student Center For Science Engagement Research Symposium, Student Center For Science Engagement

Student Center for Science Engagement Research Symposium

Student presentations in Biology, Chemistry, Physics, Earth Science, Environmental Science, Computer Science, Mathematics, & Psychology

Please note, this conference was held remotely due to the COVID-19 pandemic.

Sovereign Lands, Brent D. Chicken, Amanda J. Dick

Oil and Gas, Natural Resources, and Energy Journal

No abstract provided.

Nevada, Diana S. Prulhiere

Oil and Gas, Natural Resources, and Energy Journal

No abstract provided.

Syndrome Of Death Of Marandugrass In The Western Brazilian Amazon, Judson F. Valentim, Carlos M. S. De Andrade, Eufran Ferreira Do Amaral

IGC Proceedings (1977-2023)

No abstract provided.

Induced Plant Succession As A Strategy To Reclaim Degraded Pastures In The Brazilian Amazon, Carlos M. S. De Andrade, Judson F. Valentim

IGC Proceedings (1977-2023)

No abstract provided.

Zoning Of Risk Of Death Of Brachiaria Brizanthain The State Of Acre, Brazil, Eufran Ferreira Do Amaral, Judson F. Valentim, João Luiz Lani, Nilson Gomes Bardales, Edson Alves De Araújo, Carlos M. S. De Andrade

IGC Proceedings (1977-2023)

No abstract provided.

Restoration Of Desertified Grassland And Challenges In Northern China--For The Possibility Of Sustained Desertification Reversion, Xueyong Zhao, Halin Zhao, Xiaoan Zuo, Yayong Luo, Shaokun Wang, Zhiqiang Kou, Hao Qu

IGC Proceedings (1977-2023)

No abstract provided.

A Detailed Assessment Of Groundwater Quality In The Kabul Basin, Afghanistan, And Suitability For Future Development, Hussain Ali Jawadi, Jay Sagin, Daniel D. Snow

Nebraska Water Center: Faculty Publications

Kabul is one of the most populated cities in Afghanistan and providing resources to support this population in an arid climate presents a serious environmental challenge. The current study evaluated the quality of local Kabul Basin groundwater to determine its suitability water for drinking and irrigation purposes now and into the future. This aim was aided through groundwater parameter assessment as well as determination ofWater Quality Index (WQI) developed from 15 observation points near the city. The results of our physicochemical analysis illustrate that groundwater in the majority of areas of the Kabul Basin is not generally suitable for human …

Protein Conformational Entropy Is Not Slaved To Water, Bryan S Marques, Matthew A Stetz, Christine Jorge, Kathleen G Valentine, A Joshua Wand, Nathaniel V Nucci

College of Science & Mathematics Departmental Research

Conformational entropy can be an important element of the thermodynamics of protein functions such as the binding of ligands. The observed role for conformational entropy in modulating molecular recognition by proteins is in opposition to an often-invoked theory for the interaction of protein molecules with solvent water. The "solvent slaving" model predicts that protein motion is strongly coupled to various aspects of water such as bulk solvent viscosity and local hydration shell dynamics. Changes in conformational entropy are manifested in alterations of fast internal side chain motion that is detectable by NMR relaxation. We show here that the fast-internal side …

By Shattering The Vulture’S Nose, Melissa Yang

The Goose

This project explores an unusual ornithological debate between 19th-century naturalists John James Audubon and Charles Waterton on the olfaction of vultures. Both naturalists involved were also artists—certainly more than they were scientists—and prone to artifice and performative amplification. This article examines the rhetorical dynamics of this niche but sensational debate on avian olfaction, and its problematic influence on scientific progress.

Cross-Shelf Transport Through The Interaction Among A Coastal Jet, A Topographic Wave, And Tides, Helga Huntley, Charles W. Mcmahon, Joseph J. Kuehl, A. D. Kirwan Jr.

College of Science & Mathematics Departmental Research

Shelf break flows are often characterized by along-isobath jets with cross-shelf currents associated with tides and waves guided by variable topography. Here, we address the question: Can a superposition of such flows produce significant aperiodic cross-shelf transport? To answer this question, we use a barotropic analytic model for the jet based on a similarity solution of the shallow water equations over variable topography, a wave disturbance determined by the topography, and a diurnal tidal disturbance. We use standard Lagrangian methods to assess the cross-shelf transport, presenting the results, however, in a Eulerian frame, so as to be amenable to oceanographic …

Emergence Of Organisms., Andrea Roli, Stuart A Kauffman

Articles, Abstracts, and Reports

Since early cybernetics studies by Wiener, Pask, and Ashby, the properties of living systems are subject to deep investigations. The goals of this endeavour are both understanding and building: abstract models and general principles are sought for describing organisms, their dynamics and their ability to produce adaptive behavior. This research has achieved prominent results in fields such as artificial intelligence and artificial life. For example, today we have robots capable of exploring hostile environments with high level of self-sufficiency, planning capabilities and able to learn. Nevertheless, the discrepancy between the emergence and evolution of life and artificial systems is still …

Description Of A New Species Of Chrysina Kirby (Coleoptera: Scarabaeidae: Rutelinae) From The Sierra Azul, Oaxaca, Mexico, A New Synonymy, And Notes On Chrysina Species Found In The Sierra Azul, José Monzón Sierra, Julian Federico Blackaller-Bages, David C. Hawks

Insecta Mundi

A new species of Chrysina Kirby, C. clavellina Monzón, Blackaller, and Hawks (Coleoptera: Scarabaeidae: Rutelinae: Rutelini) is described from Santiago Clavellinas in the Sierra Azul in Oaxaca, Mexico. Chrysina cosijoezai (Ramírez-Ponce and Curoe) is placed as a junior synonym of C. lacordairei (Boucard), and notes on the Chrysina fauna of this mountain range are included.

Se describe una nueva especie de Chrysina Kirby, C. clavellina Monzón, Blackaller, y Hawks (Coleoptera: Scarabaeidae: Rutelinae) de Santiago Clavellinas en la Sierra Azul en Oaxaca, México. Chrysina cosijoezai (Ramírez-Ponce y Curoe) se sitúa como un sinónimo de C. lacordairei (Boucard) y se incluyen notas …

Dialib-Qc An Assessment Tool For Spectral Libraries In Data-Independent Acquisition Proteomics., Mukul K Midha, David S Campbell, Charu Kapil, Ulrike Kusebauch, Michael R Hoopmann, Samuel L Bader, Robert L Moritz

Articles, Abstracts, and Reports

Data-independent acquisition (DIA) mass spectrometry, also known as Sequential Window Acquisition of all Theoretical Mass Spectra (SWATH), is a popular label-free proteomics strategy to comprehensively quantify peptides/proteins utilizing mass spectral libraries to decipher inherently multiplexed spectra collected linearly across a mass range. Although there are many spectral libraries produced worldwide, the quality control of these libraries is lacking. We present the DIALib-QC (DIA library quality control) software tool for the systematic evaluation of a library's characteristics, completeness and correctness across 62 parameters of compliance, and further provide the option to improve its quality. We demonstrate its utility in assessing and …