Digital Commons Network^™

Marxist And Socialist Feminism, Elisabeth Armstrong

Study of Women, Gender, & Sexuality: Faculty Publications

Beginning in the 1840s, Marxism has analyzed unpaid, reproductive “women’s work” as an integral part of capitalism. Marxist feminism historicizes reproduction in relation to production to better understand women’s exploitation and oppression in capitalism. Marxist feminism also theorizes revolutionary subjectivity and possibilities for an anti-capitalist future. Particularly important to Marxist feminism are its theories of imperialism and primitive accumulation, or theft, of land, resources and women’s unpaid labor to the reproduction of lives and generations.

Population Pharmacokinetics Of Ribavirin In Lung Transplant Recipients And Examination Of Current And Alternative Dosing Regimens, Eliza Milliken

Theses

Ribavirin is used in the treatment of respiratory paramyxovirus infection in lung transplant recipients; however, its pharmacokinetic profile in the transplant population is unknown despite the potential for alterations due to underlying pathology. Furthermore, the ability of current regimens to meet exposure targets has not been established. This study examined the pharmacokinetics of ribavirin in a lung transplant population from which current and alternate dosing regimens were assessed. Population pharmacokinetic modelling was conducted in NONMEM using concentrationtime data from 24 lung transplant recipients and 6 healthy volunteers. Monte Carlo simulation was used to assess the ability of dosing regimens to …

Active Rehabilitation In Sports-Related Concussions: An Educational Intervention For Primary Care Providers, Lior Habinsky

Doctor of Nursing Practice Projects

Background and Review of Literature: Sports-related concussion (SRC) is a form of traumatic brain injury caused by a blow to the head and remains a prevalent issue across the 11-18-year-old age group within the United States. Historically, total physical and cognitive rest has been the preferred method to help individuals recover after suffering a concussion. However, recent data have shown that incorporating active rehabilitation or aerobic exercise therapy as part of acute post-concussion treatment is safe. Further investigation into these methods could provide valuable insight into prognosis as well as promote clinical recovery.

Purposes/Goal: This project involved delivering an educational …

Using Digital Health Technology To Optimise Older People’S Pain Self-Management Capabilities: A Mixed Methods Study (The Digitech Pain Project), Priyanka Bhattarai

Theses

Background

Arthritic pain is a major cause of illness and disability among older people. As the use of smartphones and apps increases in the lives of older people, there is an opportunity to explore the role of these apps in helping older people better manage their arthritic pain.

Aim

To explore the feasibility and acceptability of older people using an arthritic pain selfmanagement app to improve their pain symptoms.

Methods

A parallel convergent, mixed methods design underpinned by Bandura’s Self-Efficacy Theory and the Technology Acceptance Model 2; comprising of the following five studies:

(i) Study 1a: an integrative review;

(ii) …

Causes Of Variable Jarrah (Eucalyptus Marginata) And Marri (Corymbia Calophylla) Seedling Density At Establishment Following Bauxite Mining In The Northern Jarrah Forest Of Western Australia, Tai White-Toney

Theses

Seedling densities at establishment of jarrah (Eucalyptus marginata D. Don ex Sm.) and marri (Corymbia calophylla (Lindl). K. D. Hill & L. A. S. Johnson) following bauxite mining in the Northern Jarrah Forest of south-western Australia are variable and few factors explored during 40 years of field studies have explained this variability. This study explored establishment within the framework of limitation due to amount of seed supply and number of suitable microsites for establishment. First, relationships were identified between seedling establishment densities on 654 mine sites restored between 1998 and 2017 and restoration practices (seed and fertiliser application rates), climate …

Times Of The Multitude And The Antichrist, Gary Shapiro

Philosophy Faculty Publications

In Nietzsche’s Europeanism Gary Shapiro discerns key resonances of his “great politics of the Earth” out of which those capable of “re-thinking the direction of the earth” may ultimately deploy a “philosophy of the Antichrist” to realize their vision of the future. In considering how philosophers of the future may create the opportune moment in which to revalue all values in such a new direction, Shapiro accounts for Nietzsche’s rejection of the priestly philosophers’ teleological conception of time. He also explicates Nietzsche’s notion of the multitude (Menge), whose diversity contrasts with the homogenous masses and mitigates against the reactionary state.

Neonatal Abstinence Syndrome: Effectiveness Of Targeted Umbilical Cord Drug Screening In Determining Risk Of Withdrawal, Alecia Karr

DNP Projects

Neonatal Abstinence Syndrome (NAS) is a condition in which an infant experiences withdrawal from uterine exposure to various substances such as caffeine, nicotine, amphetamines, THC, opioids, benzodiazepines, and other types of substances. Depending on the severity of the symptoms, these infants may experience a longer hospital stay and may need treatment and monitoring in the neonatal intensive care unit (NICU), resulting in an increase in healthcare costs. The objective of this project was to determine if targeted drug screening of newborns was effective in determining infants at risk of NAS based on a positive screening result. This study utilized a …

Evaluating Colorectal Cancer Screening Rates In An Urban Primary Care Practice, Kristen Makowski

DNP Projects

Colorectal cancer accounts for 8% of all cancer deaths and can be prevented through timely removal of colon polyps. Despite recommendations for routine screening, approximately 31.2% of patients go unscreened for this disease (Centers for Disease Control and Prevention, 2018). The purpose of this project was to determine screening rates and documentation mechanisms for colorectal cancer in an urban primary care practice, to determine how many patients completed the screening, and to present findings to the practice providers along with exploring ways to increase screenings. An additional purpose of this project was to determine and identify patient demographics which can …

Effectiveness Of A School-Based Asthma Education Program For 8-10-Year-Old Children, Laura Hunt

DNP Projects

Background: Asthma is the most common chronic condition to affect children in the United States Five million children throughout the United States and approximately 112, 000 children in Kentucky are living with the diagnosis of asthma (CDC, 2017; CHFS, 2017). Based on current rates 1 out of 10 elementary school-age students will likely have asthma (CDC, 2019). Educating elementary-age students about asthma and symptoms of an asthma exacerbation is very important and could save a life.

Methods: A school-based asthma education program targeting children in third and fourth grades was implemented at two elementary schools in Central Kentucky. The asthma …

Cover Crops And Cover Crop Mixes: Stratification Of Biological Effects, Landon M. Gibbs

Theses and Dissertations--Plant and Soil Sciences

The potential nutrient cycling benefits from legumes (e.g. N₂-fixation) and the high biomass potential of cereal rye are well known. Further studies are warranted to evaluate bi-culture mixtures and their effects on soil nutrient stratification and microbial enzyme activity because these two properties may be differently expressed (enhanced) by legume/grass mixes. The objectives of this study were: (1) show different cover crops and cover crop mixes containing grasses and legumes differentially stratify carbon and N; (2) show the change in microbial enzyme activity in soils planted with individual cover crops relative to cover crop mixes; 3) determine the …

Nickel Speciation, Microbial Community Structure, And Chemical Attributes In The Rhizosphere Of Nickel Hyperaccumulating And Non-Accumulating Plants Growing In Serpentine Soils, James W. Morris

Theses and Dissertations--Plant and Soil Sciences

Serpentine soils are formed from weathering of serpentinite, the ultramafic parent material that provides serpentine soils with their unique identity. Weathering of serpentinite results in a plethora of edaphic factors that impose strong selection pressures on plant life, with high magnesium (Mg) to calcium (Ca) ratio, low fertility, and high levels of geologically derived metals such as cobalt (Co), chromium (Cr), and nickel (Ni). Appropriately, plant life on serpentine soils is often specialized, sparse, and endemic which in turn affects the ecosystems that develop on serpentine soils from the landscape scale down to the physiology of their inhabitants. At the …

Using Biology To Better Inform Marestail [Conyza Canadensis (L.) Cronq.] Management, Ryan James Collins

Theses and Dissertations--Plant and Soil Sciences

The importance of sustainable weed management practices continues to grow as farmers are increasingly faced with herbicide resistant weed populations. Marestail (Conyza canadensis), also known as horseweed, is a problematic weed in soybean cropping systems that has developed resistance to multiple herbicide modes of action. A two year study was conducted in Lexington, KY, examining timing patterns of marestail emergence and different integrated weed management strategies for marestail prior to no-till soybean. Treatments contained fall and spring applied herbicides with different levels of residual activities, cover crops and combinations of the two. Additionally, yields and partial budget net …

In Pursuit Of Understanding Barrel Variation: Surveying The Lignocellulose Composition And Content Changes In Quercus Alba Barrel Staves During Cooperage And Bourbon Whiskey Maturation, Jarrad Wade Gollihue

Theses and Dissertations--Plant and Soil Sciences

Bourbon whiskey is a distilled spirit which is a uniquely American with several legal requirements including 1) the major grain in the mash is corn, 2) must be aged in a new charred white oak barrel, and 3) made in the United States of America. Kentucky is the whiskey historical home, producing most of the bourbon in the United States. Interest in whiskey has developed a need to understand more about the underlying chemistry of bourbon. The charred white oak barrel used in bourbon production is of substantial interest because the barrel has been implicated in giving American whiskey its …

The Balancing Act Of Cytokinin In Environmental Stress Tolerance, Sumudu Sandeepani Karunadasa

Theses and Dissertations--Plant and Soil Sciences

Cytokinin, long known as a phytohormone that regulates plant growth and development, has been recently recognized as an important regulator of stress responses. However, our current knowledge about the mechanisms by which cytokinin regulates stress responses is fragmentary, as many of the studies in this field yielded conflicting results. Most of the work described here has focused on analyses of the molecular mechanisms of cytokinin-dependent regulation of growth and development under stress conditions, with an emphasis on the role of cytokinin-dependent regulation of protein synthesis in development and stress tolerance.

One of the important contributions of this study is the …

The Concluding Chapter: Recircumscription Of Goodenia (Goodeniaceae) To Include Four Allied Genera With An Updated Infrageneric Classification, Kelly A. Shepherd, Brendan J. Lepschi, Eden A. Johnson, Andrew G. Gardner, Emily B. Sessa, Rachel S. Jabaily

Faculty and Student Publications

© 2020. Close scrutiny of Goodenia (Goodeniaceae) and allied genera in the 'Core Goodeniaceae' over recent years has clarified our understanding of this captivating group. While expanded sampling, sequencing of multiple regions, and a genome skimming reinforced backbone clearly supported Goodenia s.l. as monophyletic and distinct from Scaevola and Coopernookia, there appears to be no synapomorphic characters that uniquely characterise this morphologically diverse clade. Within Goodenia s.l., there is strong support from nuclear, chloroplast and mitochondrial data for three major clades (Goodenia Clades A, B and C) and various subclades, which lead to earlier suggestions for the possible recognition of …

Timescales Of Variation In Diversity And Production Of Bacterioplankton Assemblages In The Lower Mississippi River, Jason T. Payne, Colin R. Jackson, Justin J. Millar, Clifford A. Ochs

Faculty and Student Publications

Copyright: © 2020 Payne et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Rivers are characterized by rapid and continuous one-way directional fluxes of flowing, aqueous habitat, chemicals, suspended particles, and resident plankton. Therefore, at any particular location in such systems there is the potential for continuous, and possibly abrupt, changes in diversity and metabolic activities of suspended biota. As microorganisms are the principal catalysts of organic matter degradation and nutrient cycling in …

The Current Application Of The Myriad And Mayo/Alice Rulings On Patent Eligibility: Inconsistent Results And Contradistinguishing Biotechnology Products, Skye Cho

Cardozo Arts & Entertainment Law Journal

The note examines the inconsistent application of the patent eligibility framework under Section 101 of the Patent Act, particularly in biotechnology. It argues that despite efforts by the USPTO to clarify the framework through memos and examples, courts have applied it inconsistently, leading to discrimination against biotechnology products. The analysis focuses on key Supreme Court decisions, such as Myriad Genetics and Mayo, and their impact on the patent eligibility of biotechnological innovations. The note highlights the need for clearer guidance to ensure consistent outcomes and fair treatment of biotechnological inventions.

Induction Of Seed Coat Darkening In Common Beans (Phaseolus Vulgaris L.) And The Association With Cooking Time After Storage, Renata C. Alvares, Helton S. Pereira, Leonardo C. Melo, Phillip N. Miklas, Patrícia G.S. Melo

United States Department of Agriculture-Agricultural Research Service / University of Nebraska-Lincoln: Faculty Publications

Carioca is the most important edible dry bean (Phaseolus vulgaris L.) grown in Brazil. It represents the largest dry bean market class in the world. The seed coat of carioca beans will darken under adverse harvest conditions and with the increasing of storage time. In general, darkened seeds are associated with older seeds that suffer from prolonged cooking times. A relatively new ‘slow darkening’ trait is available in carioca that delays seed coat darkening under storage. However, its effect on cooking time is unknown. The objective of this work was to evaluate two induction methods of seed coat darkening and …

Cropping System And Landscape Characteristics Influence Long-Term Grain Crop Profitability, L. S. Conway, M. A. Yost, Newell Kitchen, K. A. Sudduth, R. E. Massey, E. J. Sadler

United States Department of Agriculture-Agricultural Research Service / University of Nebraska-Lincoln: Faculty Publications

Converting from standard tillage or no-tillage cropping systems to more conservation-based cropping systems that include no-tillage, cover crops, and reduced agrichemical inputs must be profitable for large-scale adoption. Therefore, research was conducted at the central Mississippi River Basin site of the USDA Long-Term Agroecosystem Research Network from 1996 to 2009 to determine how cropping systems, landscape position, and depth to claypan affected net economic return. Treatments consisted of three cropping systems {mulch-till corn (Zea mays L.)–soybean [Glycine max (L.) Merr.], MTCS; no-till corn–soybean, NTCS; no-till corn–soybean–wheat (Triticum aestivum L.) (NTCSW)–cover crop} and three landscape positions (summit, backslope, and footslope). Within …

Full Issue, Journal Editors

Yalobusha Review

No abstract provided.

Law, Structural Racism, And The Covid-19 Pandemic, Ruqaiijah Yearby, Seema Mohapatra

All Faculty Scholarship

Racial and ethnic minorities have always been the most impacted by pandemics because of: disparities in exposure to the virus; disparities in susceptibility to contracting the virus; and disparities in treatment. This article explains how structural racism, the ways in which laws are used to advantage the majority and disadvantage racial and ethnic minorities, has caused these disparities. Specifically, this article focuses on how employment, housing, health care, and COVID-19 relief laws have been manipulated to disadvantage racial and ethnic minorities, making minorities more susceptible to COVID-19 infection and death. This article uses Blumenshine’s 2008 framework to outline how structural …

Structural Discrimination In Covid-19 Workplace Protections, Ruqaiijah Yearby, Seema Mohapatra

All Faculty Scholarship

Workers, who are being asked to risk their health by working outside their homes during the COVID-19 pandemic, need adequate hazard compensation, safe workplace conditions, and personal protective equipment (PPE). Sadly, this is not happening for many essential workers, such as those working in home health care and in the meat processing industry. These workers are not only being unnecessarily exposed to the virus, but they are also not receiving paid sick leave, unemployment benefits, and affordable health care and childcare. The lack of these protections is due to structural discrimination and has disproportionately disadvantaged women of color and low-wage …

The Problem With Relying On Profit-Driven Models To Produce Pandemic Drugs, Ana Santos Rutschman

All Faculty Scholarship

The longstanding problems of relying on a market response to a pandemic are becoming readily apparent in the United States, which has quickly become the epicenter of the COVID-19 outbreak. The problems are particularly pronounced in pharmaceutical markets, where we are pinning our hopes for both cures and vaccines. In previous work we have shown how characteristics of healthcare markets in the United States create a divergence between the private incentives of for-profit companies and public health needs, leading to sub-optimal health outcomes in what is a uniquely market-driven healthcare system. In this Essay, written as the COVID-19 pandemic unfolds, …

'Sex' And Religion After Bostock, Sachin S. Pandya, Marcia L. Mccormick

All Faculty Scholarship

This paper reviews the U.S. Supreme Court’s opinion in Bostock v. Clayton County. There, the Court held that by barring employer discrimination against any individual “because of such individual’s . . . sex,” Title VII of the Civil Rights Act of 1964 also bars employment discrimination because an individual is gay or transgender. The paper then speculates about how much Bostock will affect how likely lower court judges will read other “sex” discrimination prohibitions in the U.S. Code in the same way, in part based on a canvass of the text of about 150 of those prohibitions. The paper also …

Post-Traumatic Stress Disorder (Ptsd) Coverage And Other Expanding Benefit Changes In The Workers’ Compensation Insurance Marketplace: Academic Legal Perspective, Michael C. Duff

All Faculty Scholarship

This paper discusses the increased use of causation presumptions in workers' compensation cases involving firefighters and other first responders. It also considers increasing workers' compensation coverage of post traumatic stress disorder with respect to those same categories of workers. The paper discusses how workers' compensation coverage of certain conditions tends to parallel the growth of potential tort liability, observes that disease presumptions were a feature of early 20th century workers' compensation statutes (and so are not new), and argues that recognition of workers' compensation "mental-mental" claims has been consistent with "zone of danger" expansion of the negligent infliction of emotional …

Synthesis Of Radioluminescent Caf2:Ln Core, Mesoporous Silica Shell Nanoparticles For Use In X-Ray Based Theranostics, Hayden Winter, Megan J. Neufeld, Lydia Makotamo, Conroy Sun, Andrea M. Goforth

Chemistry Faculty Publications and Presentations

X-ray radiotherapy is a common method of treating cancerous tumors or other malignant lesions. The side effects of this treatment, however, can be deleterious to patient quality of life if critical tissues are affected. To potentially lower the effective doses of radiation and negative side-effects, new classes of nanoparticles are being developed to enhance reactive oxygen species production during irradiation. This report presents the synthesis and radiotherapeutic efficacy evaluation of a new nanoparticle formulation designed for this purpose, composed of a CaF₂ core, mesoporous silica shell, and polyethylene glycol coating. The construct was additionally doped with Tb and Eu …

Innovative, Yes: But Is It Rewilding?, Daniel T. Blumstein, Kate E. Lynch

Animal Sentience

Baker & Winkler’s extremely stimulating proposal clearly illustrates conflicting priorities in biodiversity conservation and management that are exacerbated when human cultural resources and animal welfare are a part of the solution. We suggest that the discussion can benefit from an even more explicit unpacking of the conflicting values associated with the proposal.

'Terroristic Threats' And Covid-19: A Guide For The Perplexed, Chad Flanders, Courtney Federico, Eric Harmon, Lucas Klein

All Faculty Scholarship

The first few months of the COVID-19 outbreak in the United States saw the rise of a troubling sort of behavior: people would cough or spit on people or otherwise threaten to spread the COVID-19 virus, resulting in panic and sometimes thousands of dollars’ worth of damages to businesses. Those who have been caught doing this — or have filmed themselves doing it — have been charged under so-called “terroristic threat” statutes. But what is a terroristic threat, and is it an appropriate charge in these cases? Surprisingly little has been written about these statutes given their long history and …

Mechanistic And Functional Shades Of Mucins And Associated Glycans In Colon Cancer, Ramesh Pothuraju, Shiv Ram Krishn, Shailendra K. Gautam, Priya Pai, Koelina Ganguly, Sanjib Chaudhary, Satyanarayana Rachagani, Sukhwinder Kaur, Surinder K. Batra

Journal Articles: Biochemistry & Molecular Biology

Mucus serves as the chief protective barrier against pathogenic and mechanical insults in respiratory, gastrointestinal, and urogenital tracts. Altered mucin expression, the major component of mucus, in conjunction with differential glycosylation has been strongly associated with both benign and malignant pathologies of colon. Mucins and their associated glycans arbitrate their impact sterically as well as mechanically by altering molecular and microbial spectrum during pathogenesis. Mucin expression in normal and pathological conditions is regulated by nonspecific (dietary factors and gut microbiota) and specific (epigenetic and transcriptional) modulators. Further, recent studies highlight the impact of altering mucin glycome (cancer-associated carbohydrate antigens including …

Size-Dependent Interactions Of Lipid-Coated Gold Nanoparticles: Developing A Better Mechanistic Understanding Through Model Cell Membranes And In Vivo Toxicity, Arek M. Engstrom, Ryan A. Faase, Joe E. Baio, Marilyn R. Mackiewicz, Stacey L. Harper

Chemistry Faculty Publications and Presentations

Introduction: Humans are intentionally exposed to gold nanoparticles (AuNPs) where they are used in variety of biomedical applications as imaging and drug delivery agents as well as diagnostic and therapeutic agents currently in clinic and in a variety of upcoming clinical trials. Consequently, it is critical that we gain a better understanding of how physiochemical properties such as size, shape, and surface chemistry drive cellular uptake and AuNP toxicity in vivo. Understanding and being able to manipulate these physiochemical properties will allow for the production of safer and more efficacious use of AuNPs in biomedical applications.
Methods and Materials: Here, …