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2020

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Articles 29161 - 29190 of 32163

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Induction Of Seed Coat Darkening In Common Beans (Phaseolus Vulgaris L.) And The Association With Cooking Time After Storage, Renata C. Alvares, Helton S. Pereira, Leonardo C. Melo, Phillip N. Miklas, Patrícia G.S. Melo Jan 2020

Induction Of Seed Coat Darkening In Common Beans (Phaseolus Vulgaris L.) And The Association With Cooking Time After Storage, Renata C. Alvares, Helton S. Pereira, Leonardo C. Melo, Phillip N. Miklas, Patrícia G.S. Melo

United States Department of Agriculture-Agricultural Research Service / University of Nebraska-Lincoln: Faculty Publications

Carioca is the most important edible dry bean (Phaseolus vulgaris L.) grown in Brazil. It represents the largest dry bean market class in the world. The seed coat of carioca beans will darken under adverse harvest conditions and with the increasing of storage time. In general, darkened seeds are associated with older seeds that suffer from prolonged cooking times. A relatively new ‘slow darkening’ trait is available in carioca that delays seed coat darkening under storage. However, its effect on cooking time is unknown. The objective of this work was to evaluate two induction methods of seed coat darkening and …

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Cropping System And Landscape Characteristics Influence Long-Term Grain Crop Profitability, L. S. Conway, M. A. Yost, Newell Kitchen, K. A. Sudduth, R. E. Massey, E. J. Sadler Jan 2020

Cropping System And Landscape Characteristics Influence Long-Term Grain Crop Profitability, L. S. Conway, M. A. Yost, Newell Kitchen, K. A. Sudduth, R. E. Massey, E. J. Sadler

United States Department of Agriculture-Agricultural Research Service / University of Nebraska-Lincoln: Faculty Publications

Converting from standard tillage or no-tillage cropping systems to more conservation-based cropping systems that include no-tillage, cover crops, and reduced agrichemical inputs must be profitable for large-scale adoption. Therefore, research was conducted at the central Mississippi River Basin site of the USDA Long-Term Agroecosystem Research Network from 1996 to 2009 to determine how cropping systems, landscape position, and depth to claypan affected net economic return. Treatments consisted of three cropping systems {mulch-till corn (Zea mays L.)–soybean [Glycine max (L.) Merr.], MTCS; no-till corn–soybean, NTCS; no-till corn–soybean–wheat (Triticum aestivum L.) (NTCSW)–cover crop} and three landscape positions (summit, backslope, and footslope). Within …

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Full Issue, Journal Editors Jan 2020

Full Issue, Journal Editors

Yalobusha Review

No abstract provided.

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Law, Structural Racism, And The Covid-19 Pandemic, Ruqaiijah Yearby, Seema Mohapatra Jan 2020

Law, Structural Racism, And The Covid-19 Pandemic, Ruqaiijah Yearby, Seema Mohapatra

All Faculty Scholarship

Racial and ethnic minorities have always been the most impacted by pandemics because of: disparities in exposure to the virus; disparities in susceptibility to contracting the virus; and disparities in treatment. This article explains how structural racism, the ways in which laws are used to advantage the majority and disadvantage racial and ethnic minorities, has caused these disparities. Specifically, this article focuses on how employment, housing, health care, and COVID-19 relief laws have been manipulated to disadvantage racial and ethnic minorities, making minorities more susceptible to COVID-19 infection and death. This article uses Blumenshine’s 2008 framework to outline how structural …

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Structural Discrimination In Covid-19 Workplace Protections, Ruqaiijah Yearby, Seema Mohapatra Jan 2020

Structural Discrimination In Covid-19 Workplace Protections, Ruqaiijah Yearby, Seema Mohapatra

All Faculty Scholarship

Workers, who are being asked to risk their health by working outside their homes during the COVID-19 pandemic, need adequate hazard compensation, safe workplace conditions, and personal protective equipment (PPE). Sadly, this is not happening for many essential workers, such as those working in home health care and in the meat processing industry. These workers are not only being unnecessarily exposed to the virus, but they are also not receiving paid sick leave, unemployment benefits, and affordable health care and childcare. The lack of these protections is due to structural discrimination and has disproportionately disadvantaged women of color and low-wage …

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The Problem With Relying On Profit-Driven Models To Produce Pandemic Drugs, Ana Santos Rutschman Jan 2020

The Problem With Relying On Profit-Driven Models To Produce Pandemic Drugs, Ana Santos Rutschman

All Faculty Scholarship

The longstanding problems of relying on a market response to a pandemic are becoming readily apparent in the United States, which has quickly become the epicenter of the COVID-19 outbreak. The problems are particularly pronounced in pharmaceutical markets, where we are pinning our hopes for both cures and vaccines. In previous work we have shown how characteristics of healthcare markets in the United States create a divergence between the private incentives of for-profit companies and public health needs, leading to sub-optimal health outcomes in what is a uniquely market-driven healthcare system. In this Essay, written as the COVID-19 pandemic unfolds, …

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'Sex' And Religion After Bostock, Sachin S. Pandya, Marcia L. Mccormick Jan 2020

'Sex' And Religion After Bostock, Sachin S. Pandya, Marcia L. Mccormick

All Faculty Scholarship

This paper reviews the U.S. Supreme Court’s opinion in Bostock v. Clayton County. There, the Court held that by barring employer discrimination against any individual “because of such individual’s . . . sex,” Title VII of the Civil Rights Act of 1964 also bars employment discrimination because an individual is gay or transgender. The paper then speculates about how much Bostock will affect how likely lower court judges will read other “sex” discrimination prohibitions in the U.S. Code in the same way, in part based on a canvass of the text of about 150 of those prohibitions. The paper also …

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Post-Traumatic Stress Disorder (Ptsd) Coverage And Other Expanding Benefit Changes In The Workers’ Compensation Insurance Marketplace: Academic Legal Perspective, Michael C. Duff Jan 2020

Post-Traumatic Stress Disorder (Ptsd) Coverage And Other Expanding Benefit Changes In The Workers’ Compensation Insurance Marketplace: Academic Legal Perspective, Michael C. Duff

All Faculty Scholarship

This paper discusses the increased use of causation presumptions in workers' compensation cases involving firefighters and other first responders. It also considers increasing workers' compensation coverage of post traumatic stress disorder with respect to those same categories of workers. The paper discusses how workers' compensation coverage of certain conditions tends to parallel the growth of potential tort liability, observes that disease presumptions were a feature of early 20th century workers' compensation statutes (and so are not new), and argues that recognition of workers' compensation "mental-mental" claims has been consistent with "zone of danger" expansion of the negligent infliction of emotional …

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Synthesis Of Radioluminescent Caf2:Ln Core, Mesoporous Silica Shell Nanoparticles For Use In X-Ray Based Theranostics, Hayden Winter, Megan J. Neufeld, Lydia Makotamo, Conroy Sun, Andrea M. Goforth Jan 2020

Synthesis Of Radioluminescent Caf2:Ln Core, Mesoporous Silica Shell Nanoparticles For Use In X-Ray Based Theranostics, Hayden Winter, Megan J. Neufeld, Lydia Makotamo, Conroy Sun, Andrea M. Goforth

Chemistry Faculty Publications and Presentations

X-ray radiotherapy is a common method of treating cancerous tumors or other malignant lesions. The side effects of this treatment, however, can be deleterious to patient quality of life if critical tissues are affected. To potentially lower the effective doses of radiation and negative side-effects, new classes of nanoparticles are being developed to enhance reactive oxygen species production during irradiation. This report presents the synthesis and radiotherapeutic efficacy evaluation of a new nanoparticle formulation designed for this purpose, composed of a CaF2 core, mesoporous silica shell, and polyethylene glycol coating. The construct was additionally doped with Tb and Eu …

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Innovative, Yes: But Is It Rewilding?, Daniel T. Blumstein, Kate E. Lynch Jan 2020

Innovative, Yes: But Is It Rewilding?, Daniel T. Blumstein, Kate E. Lynch

Animal Sentience

Baker & Winkler’s extremely stimulating proposal clearly illustrates conflicting priorities in biodiversity conservation and management that are exacerbated when human cultural resources and animal welfare are a part of the solution. We suggest that the discussion can benefit from an even more explicit unpacking of the conflicting values associated with the proposal.

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'Terroristic Threats' And Covid-19: A Guide For The Perplexed, Chad Flanders, Courtney Federico, Eric Harmon, Lucas Klein Jan 2020

'Terroristic Threats' And Covid-19: A Guide For The Perplexed, Chad Flanders, Courtney Federico, Eric Harmon, Lucas Klein

All Faculty Scholarship

The first few months of the COVID-19 outbreak in the United States saw the rise of a troubling sort of behavior: people would cough or spit on people or otherwise threaten to spread the COVID-19 virus, resulting in panic and sometimes thousands of dollars’ worth of damages to businesses. Those who have been caught doing this — or have filmed themselves doing it — have been charged under so-called “terroristic threat” statutes. But what is a terroristic threat, and is it an appropriate charge in these cases? Surprisingly little has been written about these statutes given their long history and …

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Mechanistic And Functional Shades Of Mucins And Associated Glycans In Colon Cancer, Ramesh Pothuraju, Shiv Ram Krishn, Shailendra K. Gautam, Priya Pai, Koelina Ganguly, Sanjib Chaudhary, Satyanarayana Rachagani, Sukhwinder Kaur, Surinder K. Batra Jan 2020

Mechanistic And Functional Shades Of Mucins And Associated Glycans In Colon Cancer, Ramesh Pothuraju, Shiv Ram Krishn, Shailendra K. Gautam, Priya Pai, Koelina Ganguly, Sanjib Chaudhary, Satyanarayana Rachagani, Sukhwinder Kaur, Surinder K. Batra

Journal Articles: Biochemistry & Molecular Biology

Mucus serves as the chief protective barrier against pathogenic and mechanical insults in respiratory, gastrointestinal, and urogenital tracts. Altered mucin expression, the major component of mucus, in conjunction with differential glycosylation has been strongly associated with both benign and malignant pathologies of colon. Mucins and their associated glycans arbitrate their impact sterically as well as mechanically by altering molecular and microbial spectrum during pathogenesis. Mucin expression in normal and pathological conditions is regulated by nonspecific (dietary factors and gut microbiota) and specific (epigenetic and transcriptional) modulators. Further, recent studies highlight the impact of altering mucin glycome (cancer-associated carbohydrate antigens including …

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Size-Dependent Interactions Of Lipid-Coated Gold Nanoparticles: Developing A Better Mechanistic Understanding Through Model Cell Membranes And In Vivo Toxicity, Arek M. Engstrom, Ryan A. Faase, Joe E. Baio, Marilyn R. Mackiewicz, Stacey L. Harper Jan 2020

Size-Dependent Interactions Of Lipid-Coated Gold Nanoparticles: Developing A Better Mechanistic Understanding Through Model Cell Membranes And In Vivo Toxicity, Arek M. Engstrom, Ryan A. Faase, Joe E. Baio, Marilyn R. Mackiewicz, Stacey L. Harper

Chemistry Faculty Publications and Presentations

Introduction: Humans are intentionally exposed to gold nanoparticles (AuNPs) where they are used in variety of biomedical applications as imaging and drug delivery agents as well as diagnostic and therapeutic agents currently in clinic and in a variety of upcoming clinical trials. Consequently, it is critical that we gain a better understanding of how physiochemical properties such as size, shape, and surface chemistry drive cellular uptake and AuNP toxicity in vivo. Understanding and being able to manipulate these physiochemical properties will allow for the production of safer and more efficacious use of AuNPs in biomedical applications.
Methods and Materials: Here, …

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Distribution Of Human Exposure To Ozone During Commuting Hours In Connecticut Using The Cellular Device Network, Owais Gilani, Simon Urbanek, Michael J. Kane Jan 2020

Distribution Of Human Exposure To Ozone During Commuting Hours In Connecticut Using The Cellular Device Network, Owais Gilani, Simon Urbanek, Michael J. Kane

Faculty Journal Articles

Epidemiologic studies have established associations between various air pollutants and adverse health outcomes for adults and children. Due to high costs of monitoring air pollutant concentrations for subjects enrolled in a study, statisticians predict exposure concentrations from spatial models that are developed using concentrations monitored at a few sites. In the absence of detailed information on when and where subjects move during the study window, researchers typically assume that the subjects spend their entire day at home, school, or work. This assumption can potentially lead to large exposure assignment bias. In this study, we aim to determine the distribution of …

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The Influence Of Self-Perceptions Of Attractiveness On Substance Use: Sex Differences In Predictors Of Alcohol Consumption In College Students, Ali Brenman, T. Joel Wade Jan 2020

The Influence Of Self-Perceptions Of Attractiveness On Substance Use: Sex Differences In Predictors Of Alcohol Consumption In College Students, Ali Brenman, T. Joel Wade

Faculty Journal Articles

Prior research demonstrates the negative relationship between self-esteem and alcohol use (Emery, 1993; Page, 1995; Winter, 2017), and prior research demonstrates how self-perceptions of attractiveness are fundamentally important (Barkow 1978; Wade, 2000, 2003). However, there is a paucity of research regarding exactly how self-perceptions of attractiveness, and mate value, which are related to self-esteem (Wade, Thompson, Tashakkori, Thompson, & Valente 1989; Tashakkori, Thompson, Wade, & Valente, 1990; Wade, 2000, 2003), influence alcohol consumption habits in college men and women. Using undergraduates, (66.4% female, 83.4% Caucasian), the present study examined how self-perceived attractiveness, self-esteem, mate value, sociosexuality, and sex of participant …

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Do Arthropods Respond To Noxious Stimuli Purely By Reflex?, Robert W. Elwood Jan 2020

Do Arthropods Respond To Noxious Stimuli Purely By Reflex?, Robert W. Elwood

Animal Sentience

Mikhalevich & Powell (2020) argue that it is wrong to dismiss the idea of sentience in invertebrates. Here, I expand on the evidence for crustaceans responding to noxious stimuli in ways that are not explained by mere reflexes, and that are consistent with pain. I consider the idea that male praying mantids must not feel pain because they may continue to mate whilst being consumed by the female. I finish with thoughts about the idea that because robots may be constructed to act as if they experience pain, the argument that animals might experience pain is diminished.

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The Mosaic Of Coronavirus Vaccine Development: Systemic Failures In Vaccine Innovation, Ana Santos Rutschman Jan 2020

The Mosaic Of Coronavirus Vaccine Development: Systemic Failures In Vaccine Innovation, Ana Santos Rutschman

All Faculty Scholarship

Scientists are racing to develop vaccines against the novel coronavirus. While some vaccine candidates may enter the market in record time, the current vaccine innovation ecosystem exposes governance lacunas at both the international and domestic levels.

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Production And Properties Of Resistant Maltodextrin From Cassava Starch, Kamonrat Trithavisup Jan 2020

Production And Properties Of Resistant Maltodextrin From Cassava Starch, Kamonrat Trithavisup

Chulalongkorn University Theses and Dissertations (Chula ETD)

This research aimed to determine the effects of processing conditions on molecular structure and selected properties of cassava-derived resistant dextrins (RDs) and resistant maltodextrins (RMDs). Cassava starch was mixed with hydrochloric acid solution to obtain the final acid concentration of 0.04-0.10% dry starch basis, dried at 50oC until having <5% moisture, and dextrinized at 100-120oC for 60-180 min. As acid concentration, heating temperature and time increased, water solubility, reducing sugar content, total dietary fiber (TDF) content and proportion of high molecular weight fiber fraction of RDs increased while their whiteness decreased. For the solution containing RDs produced under mild conditions (0.04-0.08% HCl, 100°C, 60 min), an endothermic peak at 45-70oC, having enthalpy of 1.66-2.14 J/g was detected. However, no endotherm was detected from the solution of RDs processed under extreme conditions. Harsher dextrinization conditions resulted in the RDs with slightly higher molecular weight but containing shorter branched chains. Dextrinization resulted in the formation of α-1,2, α-1,6, β-1,2, β-1,4 and β-1,6 in RDs. Lower proportion of α-1,4 linkage and α-/β-reducing ends with higher proportion of β-1,2, β-1,4, α-/β-1,6 linkages and degree of branching (DB) were found in RDs prepared under stronger dextrinization conditions. Although indigestible portion was enhanced by dextrinization, TDF of the RDs were only 7-47%. To increase the TDF content, RDs prepared from 5 different conditions (0.04% and 0.06% HCl, 120oC, 60-180 min), having >30% TDF, were selected for RMD production. The 30% RD solutions were treated with commercial α-amylase enzyme at 70oC, pH 6, for 90 and 120 min, to obtain the final dextrose equivalent of 8 and 12, respectively. The samples were then purified and spray dried. Alpha-amylase treatment produced RMD with shorter …

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Simple Headspace Device For Determination Of Volatile Compounds In Food And Drug Samples, Kamonwan Meesuwan Jan 2020

Simple Headspace Device For Determination Of Volatile Compounds In Food And Drug Samples, Kamonwan Meesuwan

Chulalongkorn University Theses and Dissertations (Chula ETD)

This work presented a simple alternative method for simultaneous extraction and determination of volatile compounds in complex matrix samples by combining headspace technique with paper based colorimetric method. The paper loaded with colorimetric reagent that was attached to the liner of the vial cap making a simple headspace device for direct detection of the semi-volatile and volatile compounds in headspace extraction mode. A sample was placed in a vial sealed with the paper-based headspace device. The method was tested for determination of volatile compound using ethanol as a model and semi-volatile compound using iodine as a model in complex matrix …

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Microplastics In Industrial Wastewater Treatment Plant: Quantification, Identification And Ecological Risk Assessment, Sujarat Saiwaree Jan 2020

Microplastics In Industrial Wastewater Treatment Plant: Quantification, Identification And Ecological Risk Assessment, Sujarat Saiwaree

Chulalongkorn University Theses and Dissertations (Chula ETD)

Wastewater treatment plants (WWTPs) are one of the significant pathways of microplastics (MPs) entering the environment. Thus, information regarding this issue is still requisite in Thailand. In this study, wastewater and sludge samples were collected from various treatment units of industrial WWTP in dry season (February 2020) and wet season (July 2020). The MP particles were identified by size, shape, and polymer types. From the wastewater, MPs were detected in the highest amounts after the aeration unit (134.35 ± 20.79 particles/L) in dry season sample. In addition, sludge contained relatively low MPs. The size fraction in wastewater varied, but in …

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Fabrication Of Three-Dimensional (3-D) Corneal Transplantable Model From Silk Fibroin/Gelatin-Based Biomaterial, Chutirat Torsahakul Jan 2020

Fabrication Of Three-Dimensional (3-D) Corneal Transplantable Model From Silk Fibroin/Gelatin-Based Biomaterial, Chutirat Torsahakul

Chulalongkorn University Theses and Dissertations (Chula ETD)

Canine corneal blindness is a common cause of vision loss and visual impairment worldwide. While the demand of canine corneal graft is continuously elevated, the clinical useable grafts are limited to acellular biomaterials and allograft. This study aimed to generate the tissue-engineered canine cornea in the part of corneal epithelium and underlying stroma based on cLESCs (canine limbal epithelial stem cells) seeded silk fibroin and gelatin (SF/G) film and cCSSCs (canine corneal stromal stem cells) seeded SF/G scaffold respectively. Both cell types were successfully isolated by collagenase I. SF/G films and scaffolds served as the prospective substrates for cLESCs and …

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Development Of Nanostructured Lipid Carrier Clove Oil As Anesthetic Agent In White Shrimp (Litopenaeus Vannamei), Somrudee Kaewmalun Jan 2020

Development Of Nanostructured Lipid Carrier Clove Oil As Anesthetic Agent In White Shrimp (Litopenaeus Vannamei), Somrudee Kaewmalun

Chulalongkorn University Theses and Dissertations (Chula ETD)

Clove oil is an essential oil extracted from the dried buds and leaves of the clove plant (Syzygium aromaticum). Clove oil contains eugenol as the main active ingredient. Clove oil used as an anesthesia functions as calming effect, loss of equilibrium, non-reactivity and consciousness in lead to reduce activity, physiological stress, mortality rate, and preventing cannibalism method during handling and transportation. However, the component of clove oil is insoluble in water and must be dissolved in ethanol. So, clove oil ethanolic solution leading to toxic and irritation in animal and user. In this study, to avoid this side effect, the …

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The Influence Of Polycyclic Aromatic Hydrocarbons In Fcgriib -/- Lupus Mice, Kanyarat Udompornpitak Jan 2020

The Influence Of Polycyclic Aromatic Hydrocarbons In Fcgriib -/- Lupus Mice, Kanyarat Udompornpitak

Chulalongkorn University Theses and Dissertations (Chula ETD)

The activation of aryl hydrocarbon receptor (Ahr) through polycyclic aromatic hydrocarbons (PAHs), the major components of particulate matter at 2.5 micron (PM2.5) in the polluted air, might aggravate inflammation and lupus activity. Hence, 1,4-chrysenequinone (1,4-CQ), a substance in the PAHs group, was tested in a lupus model from FcgRIIb deficiency (FcgRIIb-/-) using macrophages and mice. Although the activation by 1,4-CQ alone was unable to induce inflammation, the pre-conditioning by lipopolysaccharide (LPS), a representative inflammatory-activator, before 1,4-CQ (LPS/1,4-CQ) induced more predominant inflammation in macrophages when compared with LPS or 1,4-CQ activation alone as determined by supernatant cytokines (TNF-α, IL-6 and IL-10). …

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Molecular Detection Of Viable Mycobacterium Tuberculosis Complex In Clinical Specimens, Suthidee Petsong Jan 2020

Molecular Detection Of Viable Mycobacterium Tuberculosis Complex In Clinical Specimens, Suthidee Petsong

Chulalongkorn University Theses and Dissertations (Chula ETD)

Tuberculosis (TB) is the global health concern because of the rising incidence and mortality. TB is caused by Mycobacterium tuberculosis complex (MTBC) and transmitted via inhalation of infectious droplet nuclei circulating in the air. The World Health Organization (WHO) recommends the use of Acid-fast (AFB) smear microscopy, MTBC culture, and molecular detection of MTBC DNA for diagnosis of TB. The response to treatment should be acquired as soon as possible to reduce disease transmission and drug resistance. Although MTBC culture is a gold standard, it is laborious, expensive, and may take up to 8 weeks. The AFB staining and molecular …

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Synthesis, Characteristic And Application Of Mesocellular Foam Carbon (Mcf-C) As Catalyst For Dehydrogenation Of Ethanol, Yoottapong Klinthongchai Jan 2020

Synthesis, Characteristic And Application Of Mesocellular Foam Carbon (Mcf-C) As Catalyst For Dehydrogenation Of Ethanol, Yoottapong Klinthongchai

Chulalongkorn University Theses and Dissertations (Chula ETD)

This research aims to investigate the synthesis of MCF-C as catalyst for dehydrogenation of ethanol. The study was classified into 3 parts. In the first part, the mesocellular foam silica (MCF-Si) was converted to mesocellular foam carbon using a surfactant residue as a carbon source, and followed by testing the dehydrogenation of ethanol to acetaldehyde. Surfactant residue in the inside of MCF-Si could be used as the carbon source for MCF-C synthesis. The obtained material could maintain the meso-structure, and exhibited higher activity for ethanol dehydrogenation in comparison to MCF-Si. For the second part, MCF-C was examined for 12 h …

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The Effects Of Differentiated Reading Instruction On Reading Comprehension And Self-Efficacy Of Undergraduate Students, Prodpran Cholsakorn Jan 2020

The Effects Of Differentiated Reading Instruction On Reading Comprehension And Self-Efficacy Of Undergraduate Students, Prodpran Cholsakorn

Chulalongkorn University Theses and Dissertations (Chula ETD)

This study examined the effects of differentiated reading instruction (DRI) on the reading comprehension and self-efficacy of undergraduate students. The study indicated their improvement in both areas after the intervention. Thirty-three students attending the course of English for Scientists were chosen for the study. The pre-test in reading comprehension and the self-efficacy questionnaire were administered before the intervention. The scores of the pre-test of reading comprehension were used to divide the students into two groups according to their level of reading proficiency: lower-proficiency level students and higher-proficiency level students. The post-test of reading comprehension and that of self-efficacy was administered …

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Antioxidant And Antimicrobial Activities Of Crude Extracts Of Actinomycetes From Soils, Khaing Zar Wai Jan 2020

Antioxidant And Antimicrobial Activities Of Crude Extracts Of Actinomycetes From Soils, Khaing Zar Wai

Chulalongkorn University Theses and Dissertations (Chula ETD)

A total of 17 actinomycetes isolated from soil collected from Nong Khai, Nakhon Ratchasima, Khon Kaen, Phichit, Chachoengsao and Udonthani Province, were evaluated on antimicrobial and antioxidant activities. They were identified as Streptomyces (16 strains) and Micromonospora (1 strain) based on their phenotypic and chemotaxonomic characteristics including 16S rRNA gene sequences analysis. Strain JA03 showed 98.95% similarity of 16S rRNA gene sequence to S. puniciscabiei DSM 41929T. Strain JA03 was found to be the novel species of genus Streptomyces based on whole genome average nucleotide identity (ANI). All these strains were evaluated on antimicrobial and antioxidant activities. Based on agar …

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Effect Of Jorunnamycin A On Cancer Stem Cells Of Human Lung Cancer H460 Cells, Somruethai Sumkhemthong Jan 2020

Effect Of Jorunnamycin A On Cancer Stem Cells Of Human Lung Cancer H460 Cells, Somruethai Sumkhemthong

Chulalongkorn University Theses and Dissertations (Chula ETD)

It has been recognized that cancer stem-like cells (CSCs) in tumor tissue crucially contribute to therapeutic failure, resulting in a high mortality rate in lung cancer patients. Due to their stem-like features of self-renewal and tumor formation, CSCs can lead to drug resistance and tumor recurrence. Herein, the suppressive effect of jorunnamycin A, a bistetrahydroisoquinolinequinone isolated from Thai blue sponge Xestospongia sp., on cancer spheroid initiation and self-renewal in the CSCs of human lung cancer cells is revealed. The depletion of stemness transcription factors, including Nanog, Oct-4, and Sox2 in the lung CSC-enriched population treated with jorunnamycin A (0.5 µM), …

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Effects Of Sexism And Self-Construal On Women's Mental Intrusion And Autobiographical Memory, Natta Kambhu Jan 2020

Effects Of Sexism And Self-Construal On Women's Mental Intrusion And Autobiographical Memory, Natta Kambhu

Chulalongkorn University Theses and Dissertations (Chula ETD)

This online experiment aims to examine self-construal as a moderator to prevent negative effect, namely, mental intrusions and autobiographical memory about being incompetent, from hostile and benevolent sexism. Thai female undergraduates (N = 89) aged between 18 to 24 (M = 20.30, SD = 1.30) were recruited through convenience sampling technique. Participants were randomly assigned to either benevolent sexism or hostile sexism condition followed by one of the three self-construal written task (independent, interdependent, or no self-construal conditions). Participants completed a set of short-term memory question in order to assessed their mental intrusions during the time completing the task and …

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สภาพการอยู่อาศัยของผู้สูงอายุในโครงการหมู่บ้านจัดสรร : กรณีศึกษา โครงการหมู่บ้านนันทวัน, ทศพร มงคลนิมิตร Jan 2020

สภาพการอยู่อาศัยของผู้สูงอายุในโครงการหมู่บ้านจัดสรร : กรณีศึกษา โครงการหมู่บ้านนันทวัน, ทศพร มงคลนิมิตร

Chulalongkorn University Theses and Dissertations (Chula ETD)

เนื่องด้วยโครงสร้างประชากรผู้สูงอายุที่เพิ่มขึ้นอย่างต่อเนื่อง และงานวิจัยในผู้สูงอายุส่วนใหญ่จะเกี่ยวข้องกับผู้สูงอายุในชุมชน หรือผู้สูงอายุที่มีรายได้น้อย งานวิจัยนี้จึงมีวัตถุประสงค์เพื่อศึกษาสภาพประชากร สังคม เศรษฐกิจและพฤติกรรมการอยู่อาศัยของผู้สูงอายุในโครงการหมู่บ้านจัดสรรราคาสูง โดยเลือกกรณีศึกษาเป็นโครงการหมู่บ้านนันทวันจำนวน 3 โครงการ รวมถึงวิเคราะห์พฤติกรรมการใช้งาน ปัญหา และความต้องการด้านที่อยู่อาศัย กิจกรรม และพื้นที่ส่วนกลางภายในโครงการ เพื่อเสนอแนะแนวทางการออกแบบและแนวทางปรับปรุงพื้นที่ดังกล่าว ให้มีความเหมาะสมสําหรับผู้สูงอายุ โดยวิจัยข้อมูลจากการสัมภาษณ์และการสํารวจพื้นที่ด้านที่อยู่อาศัย อาคารสโมสรและพื้นที่ส่วนกลาง ซึ่งพบว่า ด้านพฤติกรรมคือ ผู้สูงอายุใช้เวลาภายในบ้านกับกิจกรรมดูทีวีมากเกินไป ขาดกิจกรรมที่จะช่วยส่งเสริมสุขภาพกายและสุขภาพใจให้สดใสแข็งแรง ด้านที่อยู่อาศัย มีพื้นที่บางส่วนที่ไม่เหมาะสมสำหรับผู้สูงอายุ ได้แก่ ห้องนํ้ามีขนาดเล็กเกินไป ลานซักล้างมีระดับต่างจากพื้นที่ภายในบ้าน ด้านอาคารสโมสรและพื้นที่ส่วนกลางในโครงการมีอุปสรรคต่อการใช้งานของผู้สูงอายุ ได้แก่ ตำแหน่งอาคารสโมสรที่อยู่ไกล ขาดทางลาดเพื่อใช้ในการเข้าถึงพื้นที่กิจกรรม จุดนั่งพักในสวนหรือริมทางเดินมีจำนวนน้อยเกินไป จึงเสนอแนะแนวทางการออกแบบและปรับปรุง ได้แก่ การเพิ่มกิจกรรมตามหลักทฤษฎีกิจกรรม เพื่อให้ผู้สูงอายุได้มีกลุ่มสังคมแลกเปลี่ยนความสนใจกับผู้อื่น กระตุ้นให้ร่างกายสดชื่นด้วยการเคลื่อนไหวจากกิจกรรมต่างๆ และจัดเตรียมที่อยู่อาศัยให้เหมาะสมต่อสภาพการอยู่อาศัยของผู้สูงอายุตามแนวคิดการออกแบบเพื่อทุกคน เช่น ขยายห้องน้ำให้มีขนาดใหญ่ขึ้นและติดตั้งอุปกรณ์ที่จำเป็น เช่น ราวจับ ทำทางลาดเข้าสู่ที่พักอาศัยและพื้นที่ส่วนกลางที่ผู้สูงอายุใช้งานเป็นประจำ หรือการวางเเนวทางการจัดวางสิ่งอำนวยความสะดวกที่เหมาะสมแก่ผู้สูงอายุกรณีออกแบบโครงการใหม่ เช่น การกำหนดแนวทางการวางตำแหน่งอาคารสโมสรให้อยู่กลางพื้นที่เพื่อให้ทุกคนสามารถเข้าถึงได้ในระยะที่สะดวก

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