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Articles 23071 - 23100 of 32181
Full-Text Articles in Entire DC Network
Bathypelagic Ocean Waters, Christy Linardich, Tracey Sutton, Imants G. Priede, David A. Keith
Bathypelagic Ocean Waters, Christy Linardich, Tracey Sutton, Imants G. Priede, David A. Keith
Marine & Environmental Sciences Faculty Books and Book Chapters
No abstract provided.
Mesopelagic Ocean Waters, Kate E. Watermeyer, Eduard J. Gregr, Ryan R. Rykaczewski, Imants G. Priede, Tracey Sutton, David A. Keith
Mesopelagic Ocean Waters, Kate E. Watermeyer, Eduard J. Gregr, Ryan R. Rykaczewski, Imants G. Priede, Tracey Sutton, David A. Keith
Marine & Environmental Sciences Faculty Books and Book Chapters
No abstract provided.
Undergraduate Catalog, 2020-2021, Valparaiso University
Undergraduate Catalog, 2020-2021, Valparaiso University
Undergraduate Catalogs
No abstract provided.
Niu Working Papers 2019-2020, Northern Illinois University
Niu Working Papers 2019-2020, Northern Illinois University
Working Papers
No abstract provided.
Health Care Provider’S Perspectives Of A Woman’S Quality Of Life Facing Endometriosis And Infertility, Bridget Ford
Health Care Provider’S Perspectives Of A Woman’S Quality Of Life Facing Endometriosis And Infertility, Bridget Ford
Master of Science in Nursing Theses and Projects
This study assessed the quality of life of women with endometriosis and infertility issues through the perception of health care providers. The purpose was to increase awareness of the psychosocial aspect of endometriosis to encourage health care providers to incorporate the assessment of the mental health of women diagnosed with endometriosis into care, as well as their partners. The findings of the study showed the importance of providing holistic care to women with endometriosis related infertility and the vast impact endometriosis has on mental health, relationships, and in a woman’s daily life. Implications for nurses as a result of the …
Paleoenvironments, Taphonomy, And Stable Isotopic Content Of The Terrestrial, Fossil-Vertebrate–Bearing Sequence Of The El Disecado Member, El Gallo Formation, Upper Cretaceous, Baja California, México, David Fastovsky, Marisol Montellano-Ballesteros, Henry C. Fricke, Jahandar Ramezani, Kaori Tsukui, Gregory P. Wilson, Paul Hall, Rene Hernandez-Rivera, Geraldo Alvarez
Paleoenvironments, Taphonomy, And Stable Isotopic Content Of The Terrestrial, Fossil-Vertebrate–Bearing Sequence Of The El Disecado Member, El Gallo Formation, Upper Cretaceous, Baja California, México, David Fastovsky, Marisol Montellano-Ballesteros, Henry C. Fricke, Jahandar Ramezani, Kaori Tsukui, Gregory P. Wilson, Paul Hall, Rene Hernandez-Rivera, Geraldo Alvarez
Geosciences Faculty Publications
The Late Campanian (Late Cretaceous), upper part of the El Disecado Member, El Gallo Formation, Baja California, México, preserves a rich fossil assemblage of microvertebrates and macrovertebrates, silicified logs, macroscopic plant remains, and pollen that was likely deposited as the distal part of a subaerial fan. The unit was episodic and high energy, with its salient features deriving from active river channels and sheet, debris-flow deposits. Landscape stability is indicated by the presence of compound paleosol horizons, containing Fe2O3 mottling in B horizons, cutans, and calcium carbonate concretions. All of these features indicate wet/dry cyclicity in subsurface …
A Randomized Phase Ii Trial Of Epigenetic Priming With Guadecitabine And Carboplatin In Platinum-Resistant, Recurrent Ovarian Cancer, A. M. Oza, U. A. Matulonis, A. A. Secord, J. Nemunaitis, L. D. Roman, S. P. Blagden, S. Banerjee, W. P. Mcguire, B. Schwartz, D. Matei, +18 Additional Authors
A Randomized Phase Ii Trial Of Epigenetic Priming With Guadecitabine And Carboplatin In Platinum-Resistant, Recurrent Ovarian Cancer, A. M. Oza, U. A. Matulonis, A. A. Secord, J. Nemunaitis, L. D. Roman, S. P. Blagden, S. Banerjee, W. P. Mcguire, B. Schwartz, D. Matei, +18 Additional Authors
Journal Articles
© 2020 American Association for Cancer Research Inc.. All rights reserved. Purpose: Platinum resistance in ovarian cancer is associated with epigenetic modifications. Hypomethylating agents (HMA) have been studied as carboplatin resensitizing agents in ovarian cancer. This randomized phase II trial compared guadecitabine, a second-generation HMA, and carboplatin (GþC) against second-line chemotherapy in women with measurable or detectable platinum-resistant ovarian cancer. Patients and Methods: Patients received either GþC (guadecitabine 30 mg/m2 s.c. once-daily for 5 days and carboplatin) or treatment of choice (TC; topotecan, pegylated liposomal doxorubicin, paclitaxel, or gemcitabine) in 28-day cycles until progression or unacceptable toxicity. The primary endpoint …
Seizures Induce Obstructive Apnea In Dba/2j Audiogenic Seizure-Prone Mice: Lifesaving Impact Of Tracheal Implants, R. Irizarry, D. Sukato, R. Kollmar, S. Schild, J. Silverman, K. Sundaram, S. Stephenson, M. Stewart
Seizures Induce Obstructive Apnea In Dba/2j Audiogenic Seizure-Prone Mice: Lifesaving Impact Of Tracheal Implants, R. Irizarry, D. Sukato, R. Kollmar, S. Schild, J. Silverman, K. Sundaram, S. Stephenson, M. Stewart
Journal Articles
Wiley Periodicals, Inc. © 2020 International League Against Epilepsy The mechanism(s) for sudden death in epilepsy (SUDEP) remain(s) unknown, but seizure spread to brainstem areas serving autonomic and respiratory function is critical. In a rat model, we established a mechanism for SUDEP that involves seizure-induced laryngospasm and obstructive apnea lasting until respiratory arrest. We hypothesized that DBA/2J mice, which display lethal audiogenic seizures, would be protected from death by implanting a tracheal T-tube as a surrogate airway. In a 2 × 2 design, mice were implanted with either open or closed tracheal T-tubes and treated with either low-dose ketamine/xylazine to …
The Validity Of Infrared Coagulator, And Bioglue With Antibiotics To Assist Surgical Treatment Of Infective Endocarditis?, G. Pettersson, S. Unai, S. Gordon, S. T. Hussain, E. Eriksson
The Validity Of Infrared Coagulator, And Bioglue With Antibiotics To Assist Surgical Treatment Of Infective Endocarditis?, G. Pettersson, S. Unai, S. Gordon, S. T. Hussain, E. Eriksson
Journal Articles
No abstract provided.
Pneumatosis Intestinalis In Covid-19: Case Series., K. Wong, D. H. Kim, S. Khanijo, A. Melamud, G. Zaidi
Pneumatosis Intestinalis In Covid-19: Case Series., K. Wong, D. H. Kim, S. Khanijo, A. Melamud, G. Zaidi
Journal Articles
OBJECTIVE:To describe the clinical characteristics and outcomes of patients with coronavirus disease 2019 (COVID-19) who developed pneumatosis intestinalis (PI). METHODS:This case series was conducted in intensive care units at two large tertiary care centers within the Northwell Health System, located in New York State. Patients were included if they were identified as having confirmed COVID-19 as well as pneumatosis intestinalis from March 16, 2020 to July 31, 2020. Patient demographics, clinical characteristics, vasopressor use, anticoagulation use, opiate use, paralytic use, COVID-19 treatment regimen, serum lactate, arterial pH, serum bicarbonate, subsequent intervention, and outcomes during hospitalization were collected. Results: A total …
Sars-Cov-2 And Interferon Blockade, B. Diamond, B. T. Volpe, S. Van Patten, Y. Al Abed
Sars-Cov-2 And Interferon Blockade, B. Diamond, B. T. Volpe, S. Van Patten, Y. Al Abed
Journal Articles
© 2020, The Author(s). The response to viral infection generally includes an activation of the adaptive immune response to produce cytotoxic T cells and neutralizing antibodies. We propose that SARS-CoV-2 activates the innate immune system through the renin-angiotensin and kallikrein-bradykinin pathways, blocks interferon production and reduces an effective adaptive immune response. This model has therapeutic implications.
Altered Monocyte And Langerhans Cell Innate Immunity In Patients With Recurrent Respiratory Papillomatosis (Rrp), M. Israr, J. A. Devoti, F. Lam, A. L. Abramson, B. M. Steinberg, V. R. Bonagura
Altered Monocyte And Langerhans Cell Innate Immunity In Patients With Recurrent Respiratory Papillomatosis (Rrp), M. Israr, J. A. Devoti, F. Lam, A. L. Abramson, B. M. Steinberg, V. R. Bonagura
Journal Articles
No abstract provided.
Demographics And Outcomes Of Patients With Eating Disorders Treated In Residential Care, M. Fisher, J. R. Henretty, S. A. Cox, R. Feinstein, V. Fornari, L. Moskowitz, M. Schneider, S. Levine, J. Malizio, J. Fishbein
Demographics And Outcomes Of Patients With Eating Disorders Treated In Residential Care, M. Fisher, J. R. Henretty, S. A. Cox, R. Feinstein, V. Fornari, L. Moskowitz, M. Schneider, S. Levine, J. Malizio, J. Fishbein
Journal Articles
No abstract provided.
Management Of Pediatric Systemic Lupus Erythematosus: Focus On Belimumab, M. Guzman, J. S. Hui-Yuen
Management Of Pediatric Systemic Lupus Erythematosus: Focus On Belimumab, M. Guzman, J. S. Hui-Yuen
Journal Articles
No abstract provided.
The Course Of Sars-Cov2 Infection Was Not Severe In A Crohn's Patient Who Administered Maintenance Anti-Tnf Therapy Overlapping The Early Pre-Symptomatic Period Of Infection., F. Okeke, A. Mone, A. Swaminath
The Course Of Sars-Cov2 Infection Was Not Severe In A Crohn's Patient Who Administered Maintenance Anti-Tnf Therapy Overlapping The Early Pre-Symptomatic Period Of Infection., F. Okeke, A. Mone, A. Swaminath
Journal Articles
The Inflammatory Bowel Disease (IBD) population, which may require treatment with immunosuppressive medications, may be uniquely vulnerable to COVID-19 infection. In fact, there is some evidence these medications may inhibit the cytokine storm that is theorized to cause a rapid decline seen in COVID-19. In addition, the digestive symptoms of COVID-19 can be difficult to distinguish from the activation of IBD. We present an interesting case of a Crohn's patient inadvertently administering anti-cytokine therapy during the pre-symptomatic period of COVID-19 infection. Immune suppression during early infection with SARS-COV2 risks a poor immune response to the virus and could theoretically result …
Predictors Of Bleeding In The Perioperative Anticoagulant Use For Surgery Evaluation Study, A. J. Tafur, N. P. Clark, A. C. Spyropoulos, N. Li, E. Kaplovitch, K. Macdougall, S. Schulman, J. A. Caprini, J. Douketis
Predictors Of Bleeding In The Perioperative Anticoagulant Use For Surgery Evaluation Study, A. J. Tafur, N. P. Clark, A. C. Spyropoulos, N. Li, E. Kaplovitch, K. Macdougall, S. Schulman, J. A. Caprini, J. Douketis
Journal Articles
No abstract provided.
Evaluating Of Hpv-Dna Ish As An Adjunct To P16 Testing In Oropharyngeal Cancer, J. Chi, I. R. Preeshagul, S. Sheikh-Fayyaz, S. Teckie, N. Kohn, Y. Ziemba, A. Laser, D. Frank, M. Ghaly, D. Kamdar, D. Kraus, D. Paul, N. Seetharamu
Evaluating Of Hpv-Dna Ish As An Adjunct To P16 Testing In Oropharyngeal Cancer, J. Chi, I. R. Preeshagul, S. Sheikh-Fayyaz, S. Teckie, N. Kohn, Y. Ziemba, A. Laser, D. Frank, M. Ghaly, D. Kamdar, D. Kraus, D. Paul, N. Seetharamu
Journal Articles
© 2020 Jeffrey Chi. Aim: Current guidelines recommend p16 immunohistochemistry (IHC) for testing human papillomavirus (HPV) in oropharyngeal carcinoma (OPSCC). We evaluated the value of adding DNA in situ hybridization (ISH) to p16 IHC. Methods: Fifty patients with OPSCC were analyzed. Concordance between HPV-DNA ISH and p16 IHC was measured by Gwet's agreement coefficient. Results: p16 IHC was positive in 35/48 (72.9%), negative in 8/48 (16.7%) patients. Wide spectrum DNA-ISH was positive in 9/23 (39%) and negative in 14/23 (60.9%) patients. High-risk 16/18 (HR) HPV DNA-ISH was positive in 11/23 (47.8%) and negative in 12 (52.2%) patients. The agreement between …
Deep Brain Stimulation For Refractory Obsessive-Compulsive Disorder (Ocd): Emerging Or Established Therapy?, H. Wu, M. Hariz, V. Visser-Vandewalle, L. Zrinzo, V. A. Coenen, S. A. Sheth, C. Bervoets, M. Naesstrom, M. Schulder, B. Nuttin, +45 Additional Authors
Deep Brain Stimulation For Refractory Obsessive-Compulsive Disorder (Ocd): Emerging Or Established Therapy?, H. Wu, M. Hariz, V. Visser-Vandewalle, L. Zrinzo, V. A. Coenen, S. A. Sheth, C. Bervoets, M. Naesstrom, M. Schulder, B. Nuttin, +45 Additional Authors
Journal Articles
No abstract provided.
Tdp-43 Is Elevated In Plasma Neuronal-Derived Exosomes Of Patients With Alzheimer’S Disease, N. Zhang, D. Gu, M. Meng, M. L. Gordon
Tdp-43 Is Elevated In Plasma Neuronal-Derived Exosomes Of Patients With Alzheimer’S Disease, N. Zhang, D. Gu, M. Meng, M. L. Gordon
Journal Articles
© Copyright © 2020 Zhang, Gu, Meng and Gordon. Background: Recently, TDP-43 has been recognized as a common proteinopathy in the “oldest old” and a neuropathological comorbidity in patients with Alzheimer’s disease (AD). However, since it has a low concentration in cerebrospinal fluid, the presence of TDP-43 in AD is rarely investigated in vivo. Methods: Twenty-four patients with amyloid PET confirmed AD and 15 healthy controls (HCs) were included in this study. TDP-43 level in plasma neuronal-derived exosomes (NDEs) was measured by enzyme-linked immunosorbent assay. Results: TDP-43 level was elevated in patients with AD compared with HCs (median 1.08 ng/ml, …
Systemic Inflammation In Traumatic Spinal Cord Injury, O. Bloom, P. E. Herman, A. M. Spungen
Systemic Inflammation In Traumatic Spinal Cord Injury, O. Bloom, P. E. Herman, A. M. Spungen
Journal Articles
No abstract provided.
A Pilot Study Testing A Novel 3d Printed Amphibious Lower Limb Prosthesis In A Recreational Pool Setting, T. Goldstein, A. Oreste, G. Hutnick, A. Chory, V. Chehata, J. Seldin, M. D. Gallo, O. Bloom
A Pilot Study Testing A Novel 3d Printed Amphibious Lower Limb Prosthesis In A Recreational Pool Setting, T. Goldstein, A. Oreste, G. Hutnick, A. Chory, V. Chehata, J. Seldin, M. D. Gallo, O. Bloom
Journal Articles
No abstract provided.
Relative Ratios Enhance The Diagnostic Power Of Phospholipids In Distinguishing Benign And Cancerous Ovarian Masses, T. Yagi, C. E. Kuschner, M. Shoaib, R. C. Choudhary, L. B. Becker, A. T. Lee, J. Kim
Relative Ratios Enhance The Diagnostic Power Of Phospholipids In Distinguishing Benign And Cancerous Ovarian Masses, T. Yagi, C. E. Kuschner, M. Shoaib, R. C. Choudhary, L. B. Becker, A. T. Lee, J. Kim
Journal Articles
No abstract provided.
Predictive Value Of 18F-Florbetapir And 18F-Fdg Pet For Conversion From Mild Cognitive Impairment To Alzheimer Dementia, G. Blazhenets, Y. Ma, A. Sörensen, F. Schiller, G. Rücker, D. Eidelberg, L. Frings, P. T. Meyer
Predictive Value Of 18F-Florbetapir And 18F-Fdg Pet For Conversion From Mild Cognitive Impairment To Alzheimer Dementia, G. Blazhenets, Y. Ma, A. Sörensen, F. Schiller, G. Rücker, D. Eidelberg, L. Frings, P. T. Meyer
Journal Articles
© 2020 by the Society of Nuclear Medicine and Molecular Imaging. The present study examined the predictive values of amyloid PET, 18F-FDG PET, and nonimaging predictors (alone and in combination) for development of Alzheimer dementia (AD) in a large population of patients with mild cognitive impairment (MCI). Methods: The study included 319 patients with MCI from the Alzheimer Disease Neuroimaging Initiative database. In a derivation dataset (n = 159), the following Cox proportional-hazards models were constructed, each adjusted for age and sex: amyloid PET using 18F-florbetapir (pattern expression score of an amyloid-β AD conversion-related pattern, constructed by principle-components analysis); 18F-FDG …
Hmgb1 In Systemic Lupus Erythematosus, T. Liu, M. Son, B. Diamond
Hmgb1 In Systemic Lupus Erythematosus, T. Liu, M. Son, B. Diamond
Journal Articles
No abstract provided.
Potential T Cell-Intrinsic Regulatory Roles For Irf5 Via Cytokine Modulation In T Helper Subset Differentiation And Function, Z. Brune, M. R. Rice, B. J. Barnes
Potential T Cell-Intrinsic Regulatory Roles For Irf5 Via Cytokine Modulation In T Helper Subset Differentiation And Function, Z. Brune, M. R. Rice, B. J. Barnes
Journal Articles
No abstract provided.
Modulating Cytokine Production Via Select Packaging And Secretion From Extracellular Vesicles, B. J. Barnes, C. C. Somerville
Modulating Cytokine Production Via Select Packaging And Secretion From Extracellular Vesicles, B. J. Barnes, C. C. Somerville
Journal Articles
No abstract provided.
Reproducible Metabolic Topographies Associated With Multiple System Atrophy: Network And Regional Analyses In Chinese And American Patient Cohorts, B. Shen, S. Wei, J. Ge, S. Peng, F. Liu, L. Li, S. Guo, P. Wu, D. Eidelberg, Y. Ma, +2 Additional Authors
Reproducible Metabolic Topographies Associated With Multiple System Atrophy: Network And Regional Analyses In Chinese And American Patient Cohorts, B. Shen, S. Wei, J. Ge, S. Peng, F. Liu, L. Li, S. Guo, P. Wu, D. Eidelberg, Y. Ma, +2 Additional Authors
Journal Articles
© 2020 The Authors Purpose: Multiple system atrophy (MSA) is an atypical parkinsonian syndrome and often difficult to discriminate clinically from progressive supranuclear palsy (PSP) and Parkinson's disease (PD) in early stages. Although a characteristic metabolic brain network has been reported for MSA, it is unknown whether this network can provide a clinically useful biomarker in different centers. This study was aimed to identify and cross-validate MSA-related brain network and assess its ability for differential diagnosis and clinical correlations in Chinese and American patient cohorts. Methods: We included 18F-FDG PET scans retrospectively from 128 clinically diagnosed parkinsonian patients (34 MSA, …
Nono Is A Novel Co-Factor Of Prdm1 And Regulates Inflammatory Response In Monocyte Derived-Dendritic Cells, K. Lee, S. H. Jang, H. Tian, S. J. Kim
Nono Is A Novel Co-Factor Of Prdm1 And Regulates Inflammatory Response In Monocyte Derived-Dendritic Cells, K. Lee, S. H. Jang, H. Tian, S. J. Kim
Journal Articles
© Copyright © 2020 Lee, Jang, Tian and Kim. Proper expression of the transcription factor, Positive regulatory domain 1 (PRDM1), is required for maintaining homeostasis of human monocyte derived-dendritic cells (MO-DCs). The molecular mechanisms and gene targets of PRDM1 in B and T lymphocytes have been identified. However, the function of PRDM1 in dendritic cells (DCs) remains unclear. We investigate co-regulators of PRDM1 in MO-DCs identified by mass spectrometry (MS) and co-immunoprecipitation (Co-IP). Notably, non-POU domain-containing octamer-binding protein (NonO) was found to be a PRDM1 binding protein in the nucleus of MO-DCs. NonO is recruited to the PRDM1 binding site …
Ultrasound Powered Piezoelectric Neurostimulation Devices: A Commentary., T. Sun, J. Wright, T. Datta-Chaudhuri
Ultrasound Powered Piezoelectric Neurostimulation Devices: A Commentary., T. Sun, J. Wright, T. Datta-Chaudhuri
Journal Articles
Conventional neurostimulation systems for preclinical research can be bulky and invasive due to the need for batteries or wired interfaces. Emerging as a new neural interface technique, ultrasound-powered piezoelectric neural stimulators work by converting ultrasound energy to electrical charge for neural stimulation. In addition to the benefits of wireless powering and miniaturization leading to less traumatic surgery, piezoelectric neural stimulators can also exhibit prolonged operational lifetimes for a long-term stable neural interface, and show promise for clinical translation. As one of first steps to demonstrate the value of ultrasound-powered piezoelectric neural interface, Li et al. developed a piezoelectric stimulator to …
In Utero Exposure To Endogenous Maternal Polyclonal Anti-Caspr2 Antibody Leads To Behavioral Abnormalities Resembling Autism Spectrum Disorder In Male Mice, C. Bagnall-Moreau, P. T. Huerta, D. Comoletti, A. La-Bella, R. Berlin, C. Zhao, B. T. Volpe, B. Diamond, L. Brimberg
In Utero Exposure To Endogenous Maternal Polyclonal Anti-Caspr2 Antibody Leads To Behavioral Abnormalities Resembling Autism Spectrum Disorder In Male Mice, C. Bagnall-Moreau, P. T. Huerta, D. Comoletti, A. La-Bella, R. Berlin, C. Zhao, B. T. Volpe, B. Diamond, L. Brimberg
Journal Articles
© 2020, The Author(s). The concept that exposure in utero to maternal anti-brain antibodies contributes to the development of autism spectrum disorders (ASD) has been entertained for over a decade. We determined that antibodies targeting Caspr2 are present at high frequency in mothers with brain-reactive serology and a child with ASD, and further demonstrated that exposure in utero to a monoclonal anti-Caspr2 antibody, derived from a mother of an ASD child, led to an-ASD like phenotype in male offspring. Now we propose a new model to study the effects of in utero exposure to anti-Caspr2 antibody. Dams immunized with the …