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Articles 23071 - 23100 of 818072
Full-Text Articles in Entire DC Network
Ai Enabled Service Design Approach - Demystifying The Myths, Shivani Ganwani, Karthik Konar, Simran Patankar, Sylvan Lobo, Ravi Mahamuni
Ai Enabled Service Design Approach - Demystifying The Myths, Shivani Ganwani, Karthik Konar, Simran Patankar, Sylvan Lobo, Ravi Mahamuni
ServDes Conference Series
There has been a recent surge in Artificial Intelligence (AI) adoption globally across industries. This has triggered widespread discussions about role of AI, particularly in design and creative fields. There are numerous opinions, findings and myths surrounding AI's role, capabilities, and limitations in general and in design too. This paper explores these prevalent myths and demystifies those by conducting a comprehensive literature review and offering insights from practical experiences. From our experience of using AI in different ways in varied service design projects, we argue about certain common myths about AI’s potential. We highlight where AI excels, where it falls …
Bat Observation During A Solar Eclipse In Georgia, Dalton C. Brantley, Graham B. Moore, Catherine H. Borer
Bat Observation During A Solar Eclipse In Georgia, Dalton C. Brantley, Graham B. Moore, Catherine H. Borer
Georgia Journal of Science
Eclipses are astronomical phenomena that occur infrequently enough, either spatially or temporally, that for most animals, experiencing an eclipse may only happen once in a lifetime. Thus, an eclipse can provide a unique combination of meteorological and environmental conditions, through which animal behavior can be evaluated. In this study we observed and documented bat behavior (order Chiroptera) in northwest Georgia during a partial solar eclipse in 2024. Using passive acoustic monitors at locations recognized as high quality bat habitat, we detected a single hoary bat (Lasiurus cinereus) 5 minutes before the solar eclipse peak. The bat was first …
An Overview Of The European Eel Anguilla Anguilla Fisheries In Egypt, Azza A. El Ganainy, Mohamed S. Ahmed, Mohamed F. Osman, Amany A. Mahmoud
An Overview Of The European Eel Anguilla Anguilla Fisheries In Egypt, Azza A. El Ganainy, Mohamed S. Ahmed, Mohamed F. Osman, Amany A. Mahmoud
Blue Economy
The main objective of this study is to give for the first time an overview of the geographic, seasonal and intraspecific variations in European eel (Anguilla Anguilla) stock in the Egyptian different habitats. The geographical distribution, general status as well as stocks temporal variation in Egypt are analyzed examining long term catch data sets. European eels are found in the Nile Delta and along the Mediterranean coast, occupying the brackish northern lagoons (Edko, Burullus, Manzala) and the hyper saline Bardawil lagoon. Annual total eel landings from 2013 to 2022 fluctuated, with a maximum of 1268 tons recorded in Burullus Lagoon …
Extremely Poleward Shift Of Antarctic Circumpolar Current By Eccentricity During The Last Interglacial, Lijuan Lu, Xufeng Zheng, Michael E. Weber, Victoria Peck, Brendan T. Reilly, Zhong Chen, Wen Yan, Tianyu Chen, Hong Yan, Xun Gong, Shuzhuang Wu, Liwei Zheng, Shiming Wan, Yan Du, Lisa Tauxe, Qinghua Yang, Stefanie Brachfeld, Trevor Williams, Yasmina M. Martos, Zhiheng Du, Marga García, Lara F. Pérez, Hu Yang, Bingyue Huang, Jonathan Warnock, Shuh-Ji Kao
Extremely Poleward Shift Of Antarctic Circumpolar Current By Eccentricity During The Last Interglacial, Lijuan Lu, Xufeng Zheng, Michael E. Weber, Victoria Peck, Brendan T. Reilly, Zhong Chen, Wen Yan, Tianyu Chen, Hong Yan, Xun Gong, Shuzhuang Wu, Liwei Zheng, Shiming Wan, Yan Du, Lisa Tauxe, Qinghua Yang, Stefanie Brachfeld, Trevor Williams, Yasmina M. Martos, Zhiheng Du, Marga García, Lara F. Pérez, Hu Yang, Bingyue Huang, Jonathan Warnock, Shuh-Ji Kao
Department of Earth and Environmental Studies Faculty Scholarship and Creative Works
The Antarctic Circumpolar Current (ACC) exerts substantial control on the physical, chemical, and biological properties of the Southern Ocean, playing a key role in modulating the global carbon cycle and climate. However, the orbital-scale forcing and future changes in the strength and position of the ACC remain elusive. Here, we reconstruct the history of ACC extending back to the Last Interglacial (LIG; 128-113 ka) using sediment cores from the Scotia Sea. Based on high-resolution measurements of sortable silt mean grain size, we find that bottom current speed is synchronized with eccentricity, superimposed by precession. During the LIG when both eccentricity …
Novo Nordisk Inc V. Secretary Us Dept & Health And Human Services
Novo Nordisk Inc V. Secretary Us Dept & Health And Human Services
2025 Decisions
USDC for the District of New Jersey
Exploring The Correlation Between Pupil Distance And Myopia Prevalence: An Observational Bioanthropology Study In Surabaya, Anggitha Hayuning Kinasih, Dwi Martha Nur Aditya, Y Adhimas Setyo Wicaksono
Exploring The Correlation Between Pupil Distance And Myopia Prevalence: An Observational Bioanthropology Study In Surabaya, Anggitha Hayuning Kinasih, Dwi Martha Nur Aditya, Y Adhimas Setyo Wicaksono
Folia Medica Indonesiana
Bioanthropology integrates biological and cultural perspectives, thereby enhancing our understanding of human health across populations. Myopia is a significant refractive error affecting potentially 2.5 billion people globally by the end of the decade. Bioanthropological theories suggest that pupil diameter and distance contribute to axial elongation and the progression of myopia. Nevertheless, current literature lacks empirical validation through rigorous hypothesis testing, highlighting a gap in comprehension. The research explores the relationship between pupil distance and the incidence of myopia via empirical assessments in Surabaya. An observational cross-sectional study was conducted, which involved pupil distance measurements and eye refraction assessments. Inclusion criteria …
Alloplastic Implants For Rhinoplasty: A Systematic Review And Meta-Analysis Of Clinical Outcomes And Complications, Rafeni Bunga Cikita, Beta Subakti Nataadmaja
Alloplastic Implants For Rhinoplasty: A Systematic Review And Meta-Analysis Of Clinical Outcomes And Complications, Rafeni Bunga Cikita, Beta Subakti Nataadmaja
Folia Medica Indonesiana
Alloplastic implants emphasize the importance of a comprehensive understanding of both clinical and histological aspects, which are attributed to enhancing patient satisfaction and surgical success rates. The study aims to assess the viability of different implant materials and their related risks over time. A systematic literature search was conducted across multiple databases, including PubMed, Cochrane, and EBSCOhost, to identify 79 records. After eliminating duplicates and applying specific inclusion and exclusion criteria, four new studies were included for evaluation, focusing on postoperative outcomes related to alloplastic implants in rhinoplasty. Late-onset inflammation in non-healthy capsules required removal and showed histological damage. One …
Forensic Anthropologists As “Social Workers For The Deceased”: Integrating Social Work Standards And Collaborative Efforts In Long-Term Unidentified Human Remains Cases, Amy Michael, Samantha Blatt, Jennifer Bengtson, Scotia Mullin, Juliette R. Bedard, Samantha Unwin, Jose Sanchez
Forensic Anthropologists As “Social Workers For The Deceased”: Integrating Social Work Standards And Collaborative Efforts In Long-Term Unidentified Human Remains Cases, Amy Michael, Samantha Blatt, Jennifer Bengtson, Scotia Mullin, Juliette R. Bedard, Samantha Unwin, Jose Sanchez
Human Biology Open Access Pre-Prints
Forensic anthropologists working in university laboratories are often curators of long-term unidentified human remains cases. Here, we review how and why anthropologists can effectively move toward case resolution by drawing on literature and collaborative best practices from the field of social work. Borrowing from the National Association of Social Workers (NASW) standards for case management, we detail five standards that can be effectively followed during the forensic anthropological case investigation to ensure culturally sensitive and victim-centered approaches to human identification. While the field of forensic anthropology has its own professional standards developed through a consensus body and shared governance, these …
Characterization Of Integrated Biopat® Viamass For Advanced Perfusion Process Control In Ambr® 250 High Throughput Generation 2, Ellen Lam, Philipp Kaiser, Benjamin Sommer, Frederic Houioua, Barney Zoro
Characterization Of Integrated Biopat® Viamass For Advanced Perfusion Process Control In Ambr® 250 High Throughput Generation 2, Ellen Lam, Philipp Kaiser, Benjamin Sommer, Frederic Houioua, Barney Zoro
Integrated Continuous Biomanufacturing VII (ICB VII)
Please click Additional Files below to see the full abstract
A Combination Of Machine Learning And Cfd Simulations To Enable Control And Scaling Of Continuous Bioprocesses, Christian Witz, Lukas Gsenger, Michael Wagner, Philipp Eibl, Johannes Khinast
A Combination Of Machine Learning And Cfd Simulations To Enable Control And Scaling Of Continuous Bioprocesses, Christian Witz, Lukas Gsenger, Michael Wagner, Philipp Eibl, Johannes Khinast
Integrated Continuous Biomanufacturing VII (ICB VII)
Please click Additional Files below to see the full abstract
Intensification Of Oncolytic Newcastle Disease Virus Production, Lennart Jacobtorweihe, Brice Madeline, Arnaud Léon, Yvonne Genzel, Udo Reichl
Intensification Of Oncolytic Newcastle Disease Virus Production, Lennart Jacobtorweihe, Brice Madeline, Arnaud Léon, Yvonne Genzel, Udo Reichl
Integrated Continuous Biomanufacturing VII (ICB VII)
Please click Additional Files below to see the full abstract
Integrated Continuous Downstream Process For Non-Enveloped Virus-Like Particles, Lukas Gerstweiler, Jingxiu Bi, Anton Middelberg
Integrated Continuous Downstream Process For Non-Enveloped Virus-Like Particles, Lukas Gerstweiler, Jingxiu Bi, Anton Middelberg
Integrated Continuous Biomanufacturing VII (ICB VII)
Please click Additional Files below to see the full abstract
I Am A Person Too: The State's Failure To Secure Transgender Rights And Personhood, Trevor L.M. Reynolds
I Am A Person Too: The State's Failure To Secure Transgender Rights And Personhood, Trevor L.M. Reynolds
Richmond Public Interest Law Review
The winds of change appeared to blow on June 15, 2020, when the Su- preme Court decided Bostock v. Clayton County. The Bostock decision—in which the Court held that discrimination based upon an employee’s gender identity violated Title VII of the Civil Rights Act—has been heralded as a revolutionary triumph for the LGBTQ+ community. And yet, while the Bos- tock decision dictated that employers cannot terminate people based on their gender identity, it failed in the most important regard: establishing gender identity as a protected constitutional class. The Court, however, is not unique in its failure to secure transgender rights; …
Perceived Political Party Divide During The Pandemic: A Framework Linking Attitude Strength Toward Covid-19 Vaccines To Affective Polarization, Hyungjin Gill, Heysung Lee, Soo Yun Kim, Xining Liao, Hernando Rojas
Perceived Political Party Divide During The Pandemic: A Framework Linking Attitude Strength Toward Covid-19 Vaccines To Affective Polarization, Hyungjin Gill, Heysung Lee, Soo Yun Kim, Xining Liao, Hernando Rojas
Communication Faculty Publications
This study examines how perceived political party divide may foster affective polarization during the COVID-19 pandemic. Drawing on nationally representative sample surveys of U.S. and South Korean adults, we investigate the relationship between attitude strength toward COVID-19 vaccines, perceived polarization, and affective polarization. Results suggest that individuals with stronger attitudes toward vaccines are more likely to perceive a greater ideological divide between political parties, which in turn, is associated with increased animosity toward the opposing party. Applying the mediation model to the South Korean sample yielded consistent findings, suggesting that the mechanism by which strong attitudes relate to negative emotions …
Chimes: October 6, 2025, Calvin University
Chimes: October 6, 2025, Calvin University
Chimes
Invading Hope: Embodying the Calvin community through tradition by Zach Kern & Hendrik Beelen
Calvin professors join lawsuit against Anthropic AI by Jorie Cho
"Think deeply and engage": New artwork on second Hiemenga by McKenna Wilkinson
Calvin acrobatics and tumbling rebuilds after coaching change by Evangeline Anga
Calvin's orchestra begins next chapter under new leadership by Ellery Johnson
Commitment, gratitude and celebration: Synod 2025 by Joe Toly
"In the round": How Calvin University's chapel was built to shape worship by Ella Vanden Berg
10.06.2025 Ored Connect, Liz Williamson
10.06.2025 Ored Connect, Liz Williamson
ORED Newsletter
- Field Fest
- AAAS Membership
- MIG Application Opportunity
- Contest to Promote Safe Lab Practices
Examining Student Resource Choice, Perception, And Self-Regulation In A Flipped Undergraduate Microbiology Lecture Course, Sarah Sletten
Examining Student Resource Choice, Perception, And Self-Regulation In A Flipped Undergraduate Microbiology Lecture Course, Sarah Sletten
Biomedical Sciences Faculty Publications
This study examines student resource choice, perceptions, and self-regulated learning (SRL) in preparation for a flipped undergraduate microbiology course. Drawing on Expectancy-Value Theory, the investigation explored whether students prefer video lectures or complete note sets for pre-class preparation, how SRL strategies evolve over time, and the relationship between flipped classroom perceptions and in-class engagement. Data were collected across multiple course units using surveys—including a modified Motivated Strategies for Learning Questionnaire—and analysis of resource selection and classroom participation. The results indicate a strong and increasing preference for slides over video lectures. Additionally, significant increases in higher-order cognitive strategies were observed alongside …
Intouch Week Of October 6, 2025, New York Medical College
Intouch Week Of October 6, 2025, New York Medical College
InTouch
- NYMC Goes Pink for Breast Cancer Awareness Month
- Summer Research Fellowships Empower Medical Students to Explore, Innovate, and Lead
- International Symposium on Adolescent and Young Adult NHL Has Far Reach
- A Look Inside NYMC with the 2025-2026 Social Media Ambassadors
- SOM Welcomes New Faculty
- Pet the Stress Away Brings Joy to NYMC
- Stay Warm with Savings on Hoodies
- In The Community: College Joins Forces at Westchester Heart Walk to Fight Heart Disease and Stroke
- In The Community: SHSP Students and Faculty Partner with the White Plains Youth Bureau for Community Health and Wellness Day
- Faculty Spotlight: Christopher Whitehurst, Ph.D., Cracks …
Dieticians’ Perceptions Of Pediatric Obesity Education In Children’S Hospitals Located In Northeast Maryland, Constance Bartu
Dieticians’ Perceptions Of Pediatric Obesity Education In Children’S Hospitals Located In Northeast Maryland, Constance Bartu
Walden Dissertations and Doctoral Studies
Dieticians play a vital role in the fight against pediatric obesity in the United States. The purpose of this qualitative study was to explore dieticians’ perceptions of internal and external reinforcements and barriers to childhood obesity interventions in children’s hospitals within Northeast Maryland. The study was framed by the social cognitive theory described by Bandura. As applied to this study, the theory focuses on prevention and intervention strategies used by dieticians working in children’s hospitals while offering educational interventions and other health care services. Interviews were conducted with eight dieticians with a minimum of 4 years working in children’s hospitals …
Strategies To Improve Access To Clinical Informatics Specialist Consultations In An Acute Care Hospital System, Holli Miller
Strategies To Improve Access To Clinical Informatics Specialist Consultations In An Acute Care Hospital System, Holli Miller
Walden Dissertations and Doctoral Studies
Access to clinical informatics specialist (CIS) consultations is essential for optimizing electronic health record (EHR) use in acute care hospital systems. Limited availability of CIS support contributes to clinician burnout, workflow inefficiencies, and patient safety risks. The purpose of this integrative review was to identify strategies to improve access to CIS consultations in acute care settings. A comprehensive literature search across multiple databases yielded 656 articles, with 24 meeting inclusion criteria based on relevance and methodological rigor, evaluated using the Johns Hopkins Nursing Evidence-Based Practice appraisal tools. These studies, published between 2019 and 2024, underwent thematic analysis guided by the …
Perceptions Of Whole Plant-Based Diets And Weight Among Hispanics In Miami, Florida, Zoraida Powell
Perceptions Of Whole Plant-Based Diets And Weight Among Hispanics In Miami, Florida, Zoraida Powell
Walden Dissertations and Doctoral Studies
Being overweight or obese poses major public health concerns and contributes to the development of chronic illnesses. While researchers have explored how a total plant-based diet impacts excess body weight or obesity, there is still a lack of clarity about how Hispanics living in Miami, FL, perceive or understand this diet concerning overweight and obesity. Using a generic qualitative approach, this study was conducted on how Hispanics in Miami, FL, understand and view a whole plant-based diet (WPBD) for preventing and reducing overweight and obesity. Through interviews with 14 diverse Hispanic participants, the study revealed that they see WPBD as …
Rurality’S Impact On Alaska Native Elders’ Levels Of Physical Activity And Obesity, Jessie Doherty
Rurality’S Impact On Alaska Native Elders’ Levels Of Physical Activity And Obesity, Jessie Doherty
Walden Dissertations and Doctoral Studies
While there have been studies on obesity levels and physical activity levels across many populations and age groups, few studies have focused on Alaska Native Elders. The purpose of this study was to examine rurality (urban vs. rural counties), physical activity, and obesity level while controlling for sex, self-reported loneliness, and self-reported stress. The theoretical foundation for this study was based on the socio-ecological model (SEM), and the research questions in this study explored how rurality impacted obesity levels and how rurality impacted physical activity levels in Alaska Native Elders. The methodology of this study was a quantitative cross-sectional design …
Practicing With Intent: How To Teach An Old Dogma New Tricks, Matthew C Phillips, Kusha Davar, Sarah Freling, Steven Y C Tong, Todd C Lee, Emily G Mcdonald, Travis B Nielsen, Noah Wald-Dickler, Alfredo J Mena Lora, Rachael A Lee, Fergus Hamilton, Daniel M Musher, Rodrigo P L Costa, Bassam Ghanem, Rachel Baden, Brad Spellberg
Practicing With Intent: How To Teach An Old Dogma New Tricks, Matthew C Phillips, Kusha Davar, Sarah Freling, Steven Y C Tong, Todd C Lee, Emily G Mcdonald, Travis B Nielsen, Noah Wald-Dickler, Alfredo J Mena Lora, Rachael A Lee, Fergus Hamilton, Daniel M Musher, Rodrigo P L Costa, Bassam Ghanem, Rachel Baden, Brad Spellberg
Faculty, Staff and Students Publications
Clinicians are constantly bombarded with an onslaught of newly published data, yet they must make clinical decisions despite a dearth of clinical data. Sometimes, they may fall back on clinical practices entrenched by experience, unaware that they are upheld by dogmatic tradition rather than robust evidence. Ideally, the totality of evidence must be assessed and utilized for clinical decision-making, irrespective of entrenched orthodoxy. Here, we explore the questions, how much evidence is needed to revise established clinical practices and, more fundamentally, can data alone truly catalyze such shifts.
Strain-Specific Variability In Viral Kinetics, Cytokine Response, And Cellular Damage In Air-Liquid Cultures Of Human Nasal Organoids After Infection With Sars-Cov-2, Gina M Aloisio, Trevor J Mcbride, Letisha Aideyan, Emily M Schultz, Ashley M Murray, Anubama Rajan, Erin G Nicholson, David Henke, Laura Ferlic-Stark, Amal Kambal, Hannah L Johnson, Elina A Mosa, Fabio Stossi, Sarah E Blutt, Pedro A Piedra, Vasanthi Avadhanula
Strain-Specific Variability In Viral Kinetics, Cytokine Response, And Cellular Damage In Air-Liquid Cultures Of Human Nasal Organoids After Infection With Sars-Cov-2, Gina M Aloisio, Trevor J Mcbride, Letisha Aideyan, Emily M Schultz, Ashley M Murray, Anubama Rajan, Erin G Nicholson, David Henke, Laura Ferlic-Stark, Amal Kambal, Hannah L Johnson, Elina A Mosa, Fabio Stossi, Sarah E Blutt, Pedro A Piedra, Vasanthi Avadhanula
Faculty, Staff and Students Publications
SARS-CoV-2 variants have demonstrated distinct epidemiological patterns and clinical presentations throughout the COVID-19 pandemic. Understanding variant-specific differences at the respiratory epithelium is crucial for understanding their pathogenesis. Here, we utilized human nasal organoid air-liquid interface (HNO-ALI) cell cultures to compare the viral replication kinetics, innate immune response, and epithelial damage of six different strains of SARS-CoV-2 (B.1.2, WA, Alpha, Beta, Delta, and Omicron). All variants replicated efficiently in HNO-ALIs, but with distinct replication kinetic patterns. The Delta variant exhibited delayed replication kinetics, achieving a steady state at 6 days post-infection compared to 3 days for other variants. Cytokine analysis revealed …
Fema Public Policy Impacts On Emergency Preparedness In Florida, Sara Sambolin
Fema Public Policy Impacts On Emergency Preparedness In Florida, Sara Sambolin
Walden Dissertations and Doctoral Studies
Older adults are at an increased risk of mortality during hazardous emergencies; therefore, it is crucial to comprehend how current emergency preparedness policies are related to preparedness perceptions of older adults. Findings in recent literature identified the underrepresentation of older adults in Emergency Preparedness studies across all areas and Counties of the state of Florida as a gap that needs to be addressed. The purpose of this quantitative correlational study was to examine the relationship between the 2023 FEMA policy on emergency preparedness and the self-reported degree of preparedness among Florida’s older adult residents in urban and rural areas across …
Atg Conjugation-Dependent/Independent Mechanisms Underlie Lysosomal Stress-Induced Tfeb Regulation, Shiori Akayama, Takayuki Shima, Tatsuya Kaminishi, Mengying Cui, Jlenia Monfregola, Kohei Nishino, Andrea Ballabio, Hidetaka Kosako, Tamotsu Yoshimori, Shuhei Nakamura
Atg Conjugation-Dependent/Independent Mechanisms Underlie Lysosomal Stress-Induced Tfeb Regulation, Shiori Akayama, Takayuki Shima, Tatsuya Kaminishi, Mengying Cui, Jlenia Monfregola, Kohei Nishino, Andrea Ballabio, Hidetaka Kosako, Tamotsu Yoshimori, Shuhei Nakamura
Duncan NRI Faculty and Staff Publications
TFEB, a master regulator of autophagy and lysosomal biogenesis, is activated by several cellular stresses including lysosomal damage, but its underlying mechanism is unclear. TFEB activation during lysosomal damage depends on the ATG conjugation system, which mediates lipidation of ATG8 proteins. Here, we newly identify ATG conjugation-independent TFEB regulation that precedes ATG conjugation-dependent regulation, designated Modes I and II, respectively. We reveal unique regulators of TFEB in each mode: APEX1 in Mode I and CCT7 and/or TRIP6 in Mode II. APEX1 interacts with TFEB independently of the ATG conjugation system, and is required for TFEB stability, while both CCT7 and …
Atg16l1 Controls Mammalian Vacuolar Proton Atpase, Thabata L A Duque, Masroor Paddar, Einar Trosdal, Ruheena Javed, Lee Allers, Michal H Mudd, Prithvi Akepati, Soumya R Mishra, Michelle Salemi, Brett Phinney, Shawn B Bratton, Thomas Wileman, Vojo Deretic
Atg16l1 Controls Mammalian Vacuolar Proton Atpase, Thabata L A Duque, Masroor Paddar, Einar Trosdal, Ruheena Javed, Lee Allers, Michal H Mudd, Prithvi Akepati, Soumya R Mishra, Michelle Salemi, Brett Phinney, Shawn B Bratton, Thomas Wileman, Vojo Deretic
Faculty, Staff and Student Publications
The mechanisms governing mammalian proton pump V-ATPase function are of fundamental and medical interest. The assembly and disassembly of cytoplasmic V1 domain with the membrane-embedded V0 domain of V-ATPase is a key aspect of V-ATPase localization and function. Here, we show that the mammalian protein ATG16L1, primarily appreciated for its role in canonical autophagy and in noncanonical membrane atg8ylation processes, controls V-ATPase. ATG16L1 knockout elevated V-ATPase activity, increased V1 presence on endomembranes, and increased the number of acidified intracellular compartments. ATG16L1's ability to efficiently bind V-ATPase was required for its inhibitory role in endolysosomal acidification and for control of Mycobacterium …
Improved Allele Frequencies In Gnomad Through Local Ancestry Inference, Pragati Kore, Michael W Wilson, Grace Tiao, Katherine Chao, Philip W Darnowsky, Nicholas A Watts, Jessica Honorato Mauer, Samantha M Baxter, Genome Aggregation Database Consortium, Heidi L Rehm, Mark J Daly, Konrad J Karczewski, Elizabeth G Atkinson
Improved Allele Frequencies In Gnomad Through Local Ancestry Inference, Pragati Kore, Michael W Wilson, Grace Tiao, Katherine Chao, Philip W Darnowsky, Nicholas A Watts, Jessica Honorato Mauer, Samantha M Baxter, Genome Aggregation Database Consortium, Heidi L Rehm, Mark J Daly, Konrad J Karczewski, Elizabeth G Atkinson
Faculty, Staff and Students Publications
The Genome Aggregation Database (gnomAD) is a foundational resource for allele frequency data, widely used in genomic research and clinical interpretation. However, traditional estimates rely on individual-level genetic ancestry groupings that may obscure variation in recently admixed populations. To improve resolution, we applied local ancestry inference (LAI) to over 27 million variants in two admixed groups: Admixed American (n = 7612) and African/African American (n = 20,250), deriving ancestry-specific allele frequencies. We show that 78.5% and 85.1% of variants in these groups, respectively, exhibit at least a twofold difference in ancestry-specific frequencies. Moreover, 81.49% of variants with LAI information would …
Phytochemisty And Antioxidant Activity Of Ethanol, Ethyl Acetate, And N-Hexane Extracts Of Suruhan Leaves (Peperomia Pellucida), Ade Arsianti, Steven Gill, Diyah Kristanty
Phytochemisty And Antioxidant Activity Of Ethanol, Ethyl Acetate, And N-Hexane Extracts Of Suruhan Leaves (Peperomia Pellucida), Ade Arsianti, Steven Gill, Diyah Kristanty
Indonesian Journal of Medical Chemistry and Bioinformatics
Background: Free radicals are natural byproducts of cellular metabolism, in which, their excessive accumulation can lead to oxidative stress, which plays a key role in the development of various chronic diseases, including cancer, cardiovascular disorders, and neurodegenerative conditions. Antioxidants are compounds capable of scavenging free radicals and minimizing oxidative damage. Peperomia pellucida, commonly known as Suruhan leaves, is a tropical herb traditionally used in folk medicine that contain bioactive compounds correlated with a strong radical-scavenging activity, suggesting its potential as a natural antioxidant source. This study aims to conduct a phytochemical analysis and evaluate the antioxidant activity of ethanol, …
Re: Butte Priority Soils Operable Unit (Bpsou) Final Reclamation Improvement Sites Field Sampling And Investigation Plan (Fsp): Bres No. 45 – Garfield, Mike Mcanulty
Silver Bow Creek/Butte Area Superfund Site
No abstract provided.