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2020

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Perspective Taking As Virtual Navigation? Perceptual Simulation Of What Others See Reflects Their Location In Space But Not Their Gaze, Eleanor Ward, Giorgio Ganis, Katrina L. Mcdonough, Patric Bach Jan 2020

Perspective Taking As Virtual Navigation? Perceptual Simulation Of What Others See Reflects Their Location In Space But Not Their Gaze, Eleanor Ward, Giorgio Ganis, Katrina L. Mcdonough, Patric Bach

School of Psychology

No abstract provided.


Rivals Without A Cause? Relative Performance Feedback Creates Destructive Competition Despite Aligned Incentives, Jan K. Woike, Sebastian Hafenbrädl Jan 2020

Rivals Without A Cause? Relative Performance Feedback Creates Destructive Competition Despite Aligned Incentives, Jan K. Woike, Sebastian Hafenbrädl

School of Psychology

No abstract provided.


Nutrition-Related Symptoms In Adult Survivors Of Critical Illness Who Are Eating Orally: A Scoping Review Protocol., Louise Albrich, Lee Anne S. Chapple, Amelia Nock, Emma J. Ridley, Mary Hickson Jan 2020

Nutrition-Related Symptoms In Adult Survivors Of Critical Illness Who Are Eating Orally: A Scoping Review Protocol., Louise Albrich, Lee Anne S. Chapple, Amelia Nock, Emma J. Ridley, Mary Hickson

School of Health Professions

OBJECTIVE: This review will explore and map the current literature on the nutritional impact of symptoms reported by adult survivors of critical illness who are eating orally after discharge from the intensive care unit (ICU). INTRODUCTION: Survivors of critical care often experience ICU-acquired weakness and poor functional recovery. It is plausible that nutrition interventions throughout their recovery could improve outcomes for these patients. Although a growing number of studies aim to explore the effect of nutrition delivered in the early phases of critical illness, this is also important post-ICU discharge, particularly in already nutritionally compromised patients presenting with muscle loss …


Enhancing Creativity By Training Metacognitive Skills In Mental Imagery, Jon May, Emma Redding, Sarah Whatley, Klara Łucznik, Lucie Clements, Rebecca Weber, John Sikorski, Sara Reed Jan 2020

Enhancing Creativity By Training Metacognitive Skills In Mental Imagery, Jon May, Emma Redding, Sarah Whatley, Klara Łucznik, Lucie Clements, Rebecca Weber, John Sikorski, Sara Reed

School of Psychology

No abstract provided.


Polyvinyl Chloride (Pvc) Plastic Fragments Release Pb Additives That Are Bioavailable In Zebrafish, David Boyle, Ana I. Catarino, Nathaniel J. Clark, Theodore B. Henry Jan 2020

Polyvinyl Chloride (Pvc) Plastic Fragments Release Pb Additives That Are Bioavailable In Zebrafish, David Boyle, Ana I. Catarino, Nathaniel J. Clark, Theodore B. Henry

School of Health Professions

No abstract provided.


Feasibility, Acceptability And Cost Efficiency Of Using Webinars To Deliver First‐Line Patient Education For People With Irritable Bowel Syndrome As Part Of A Dietetic‐Led Gastroenterology Service In Primary Care, M. Williams, Y. Barclay, L. Harper, C. Marchant, L. Seamark, M. Hickson Jan 2020

Feasibility, Acceptability And Cost Efficiency Of Using Webinars To Deliver First‐Line Patient Education For People With Irritable Bowel Syndrome As Part Of A Dietetic‐Led Gastroenterology Service In Primary Care, M. Williams, Y. Barclay, L. Harper, C. Marchant, L. Seamark, M. Hickson

School of Health Professions

No abstract provided.


Exploring Senior School Leaders And Parents Perspectives On Illegal School Exclusions Or 'Off Rolling' In England, E Done, Helen Knowler Jan 2020

Exploring Senior School Leaders And Parents Perspectives On Illegal School Exclusions Or 'Off Rolling' In England, E Done, Helen Knowler

School of Law, Humanities and Social Sciences

No abstract provided.


Ambiguity In Psychology, J May Jan 2020

Ambiguity In Psychology, J May

School of Psychology

No abstract provided.


Reforming Medical Regulation: A Qualitative Study Of The Implementation Of Medical Revalidation In England, Using Normalization Process Theory, Abigail Tazzyman, Jane Ferguson, Alan Boyd, Marie Bryce, John Tredinnick-Rowe, Tristan Price, Kieran Walshe Jan 2020

Reforming Medical Regulation: A Qualitative Study Of The Implementation Of Medical Revalidation In England, Using Normalization Process Theory, Abigail Tazzyman, Jane Ferguson, Alan Boyd, Marie Bryce, John Tredinnick-Rowe, Tristan Price, Kieran Walshe

Peninsula Medical School

Objectives The introduction of medical revalidation in 2012 has been a controversial and radical change to medical regulation in the UK. It involved changes to the way organizations manage medical performance, and to the relationships between doctors, their employers and the professional regulatory body. In this paper, we explore the implementation of medical revalidation, analysing the change process and its consequences for doctors and organizations. Methods We conducted a qualitative investigation of the implementation of revalidation in 15 case study organizations in 2016–2017, collecting documents and undertaking a total of 80 interviews with medical and non-medical staff. We used Normalization …


Introduction To Creative And Collaborative Approaches To Research And Practice With A Social And Criminal Justice Focus, Julie Parsons, Gayle Letherby Jan 2020

Introduction To Creative And Collaborative Approaches To Research And Practice With A Social And Criminal Justice Focus, Julie Parsons, Gayle Letherby

School of Law, Humanities and Social Sciences

An introduction to creative and collaborative approaches to research and practice, with a social and criminal justice focus.


Cognition And Its Relation To Brain Health In Patients With Ms: Response To Letter, Jeremy Hobart, Gavin Giovannoni Jan 2020

Cognition And Its Relation To Brain Health In Patients With Ms: Response To Letter, Jeremy Hobart, Gavin Giovannoni

Peninsula Medical School

No abstract provided.


Contrasting Impact Of Androgens On Male And Female Adiposity, Fat Distribution And Insulin Resistance In Childhood And Adolescence (Earlybird 75), Jade Chynoweth, Joanne Hosking, Alison Jeffery, Jonathan Pinkney Jan 2020

Contrasting Impact Of Androgens On Male And Female Adiposity, Fat Distribution And Insulin Resistance In Childhood And Adolescence (Earlybird 75), Jade Chynoweth, Joanne Hosking, Alison Jeffery, Jonathan Pinkney

Peninsula Medical School

Objectives: To investigate associations between androgens (testosterone, dehydroepiandrosterone sulphate [DHEAS] and androstenedione), adiposity, fat distribution and insulin resistance (IR) during childhood and adolescence. Methods: Three hundred and seven children (170 [55.4%] boys; 137 [44.6%] girls)recruited at age 5 and studied annually until age 16: androgens (liquid chromatography tandem-mass spectrometry), anthropometry, body composition (dual-energy x-ray absorptiometry) and IR (homeostasis model assessment). Results: Early adiposity was associated with earlier detection of androstenedione in both sexes, and DHEAS in boys. At puberty, higher androgen levels were associated with favourable metabolic changes in boys, but adverse metabolic effects in girls. In boys, higher free …


British Obesity And Metabolic Surgery Society Guidelines On Perioperative And Postoperative Biochemical Monitoring And Micronutrient Replacement For Patients Undergoing Bariatric Surgery—2020 Update, Mary O'Kane, Helen M. Parretti, Jonathan Pinkney, Richard Welbourn, Carly A. Hughes, Jessica Mok, Nerissa Walker, Denise Thomas, Jennifer Devin, Karen D. Coulman, Gail Pinnock, Rachel L. Batterham, Kamal K. Mahawar, Manisha Sharma, Alex I. Blakemore, Iris Mcmillan, Julian H. Barth Jan 2020

British Obesity And Metabolic Surgery Society Guidelines On Perioperative And Postoperative Biochemical Monitoring And Micronutrient Replacement For Patients Undergoing Bariatric Surgery—2020 Update, Mary O'Kane, Helen M. Parretti, Jonathan Pinkney, Richard Welbourn, Carly A. Hughes, Jessica Mok, Nerissa Walker, Denise Thomas, Jennifer Devin, Karen D. Coulman, Gail Pinnock, Rachel L. Batterham, Kamal K. Mahawar, Manisha Sharma, Alex I. Blakemore, Iris Mcmillan, Julian H. Barth

Peninsula Medical School

No abstract provided.


Assessment Of Patients With Lower Urinary Tract Symptoms Where An Undiagnosed Neurological Disease Is Suspected: A Report From An International Continence Society Consensus Working Group, Holly A. Roy, Jeremy Nettleton, Camilla Blain, Catherine Dalton, Bilal Farhan, Ailton Fernandes, Petros Georgopoulos, Sabine Klepsch, John Lavelle, Evangelista Martinelli, Jalesh N. Panicker, Ivan Radoja, Christina Anastasia Rapidi, E Silva R Pereira, Katarina Tudor, Adrian S. Wagg, Marcus J. Drake Jan 2020

Assessment Of Patients With Lower Urinary Tract Symptoms Where An Undiagnosed Neurological Disease Is Suspected: A Report From An International Continence Society Consensus Working Group, Holly A. Roy, Jeremy Nettleton, Camilla Blain, Catherine Dalton, Bilal Farhan, Ailton Fernandes, Petros Georgopoulos, Sabine Klepsch, John Lavelle, Evangelista Martinelli, Jalesh N. Panicker, Ivan Radoja, Christina Anastasia Rapidi, E Silva R Pereira, Katarina Tudor, Adrian S. Wagg, Marcus J. Drake

Peninsula Medical School

AimLower urinary tract symptoms (LUTS) are a common urological referral, which sometimes can have a neurological basis in a patient with no formally diagnosed neurological disease (“occult neurology”). Early identification and specialist input is needed to avoid bad LUTS outcomes, and to initiate suitable neurological management.MethodsThe International Continence Society established a neurological working group to consider: Which neurological conditions may include LUTS as an early feature? What diagnostic evaluations should be undertaken in the LUTS clinic? A shortlist of conditions was drawn up by expert consensus and discussed at the annual congress of the International Neurourology Society. A multidisciplinary working …


Social Connectedness And Financial Independence Strategies Supporting Nonprofit Sustainability, Christopher Edmund Maylor Jan 2020

Social Connectedness And Financial Independence Strategies Supporting Nonprofit Sustainability, Christopher Edmund Maylor

Walden Dissertations and Doctoral Studies

Leaders of nonprofit organizations (NPOs) often lack strategies to ensure the sustainability of their organizations beyond initial funding, resulting in significant risk to program continuity. Grounded in social entrepreneurship theory, the purpose of this qualitative single-case study was to explore strategies used by 3 leaders of a small NPO in the southwest region of the United States. Data were collected from semistructured interviews and a review of organizational documents. Through thematic analysis, 6 social themes emerged: optimization of business strategies, income and donor growth, program cost management, funding diversification, program licensing, and public awareness of NPO programs. The contributions to …


Creative Technologies For Behaviour Change, Joana Galvao Gomes Da Silva Jan 2020

Creative Technologies For Behaviour Change, Joana Galvao Gomes Da Silva

Other Faculty of Health Theses

This thesis presents innovative uses of technology to support motivation, using motivational interviewing (MI) and functional imagery training (FIT) scripts developed specifically for remote delivery. MI scripts aimed to develop discrepancy, evoke solutions and promote self-efficacy. FIT scripts included multi-sensory mental imagery exercises at key points in the MI scripts. Four methods of delivery were developed: a human video-counsellor, a NAO robot programmed with Choregraphe software, a video robot counsellor for comparison with the human video-counsellor, and a life-sized two dimensional 'holographic' projection. Four empirical studies tested these developments in participants wanting to become more physically active. Study 1 (N=18) …


An Evaluation Of The Incremental Value Of Computed Tomographic Biomarkers In Cardiovascular Risk Prediction, Chun Lap Pang Jan 2020

An Evaluation Of The Incremental Value Of Computed Tomographic Biomarkers In Cardiovascular Risk Prediction, Chun Lap Pang

Other Faculty of Health Theses

Predicting cardiovascular events is an important subject in the developed world as it is a major cause of morbidity and mortality. Identifying those at risk of developing cardiovascular disease is key as there are treatments available to reduce the risk of future events. The most well-known prediction tool is the Framingham Risk Score (FRS), a multivariate cardiovascular risk prediction model. The Framingham cohort identified some of the most fundamental risk factors that shape modern cardiovascular prevention, however, it is not a perfect model. The imperfect nature of cardiovascular risk prediction based on FRS forms the starting point of this research …


Self‐Perceived Preparedness Of Undergraduate Dental Students In Dental Public Universities In Malaysia: A National Study, Yudin Z Mat, K Ali, Ahmad Wma Wan, A Ahmad, Mf Khamis, Graville Monteiro Na Brian, Ab Aziz Za Che, R Saub, Ti Rosli, A Alias, Hamid Nf Abdul, Na Harun Jan 2020

Self‐Perceived Preparedness Of Undergraduate Dental Students In Dental Public Universities In Malaysia: A National Study, Yudin Z Mat, K Ali, Ahmad Wma Wan, A Ahmad, Mf Khamis, Graville Monteiro Na Brian, Ab Aziz Za Che, R Saub, Ti Rosli, A Alias, Hamid Nf Abdul, Na Harun

Peninsula Dental School

No abstract provided.


Current Uses Of Chlorhexidine For Management Of Oral Disease: A Narrative Review, Zoë L.S. Brookes, Raul Bescos, Louise A. Belfield, Kamran Ali, Anthony Roberts Jan 2020

Current Uses Of Chlorhexidine For Management Of Oral Disease: A Narrative Review, Zoë L.S. Brookes, Raul Bescos, Louise A. Belfield, Kamran Ali, Anthony Roberts

Peninsula Dental School

ObjectivesChlorhexidine (CHX) is a commonly used antiseptic mouthwash, used by dental practitioners and the public, due to its antimicrobial effects. The aim of this article was to provide a narrative review of current antimicrobial uses of CHX relevant to dentistry in the context of oral diseases, highlighting need for further studies to support its safe and appropriate use.Study selection, data and sourcesRandomised controlled trials, systematic reviews and national (UK and US) guidelines were consulted where available, with search terms for each subject category entered into MEDLINE, PubMed, Google Scholar and the Cochrane database.ResultsSome evidence existed to support adjunctive short-term use …


Homelessness On The Curriculum?, R. Witton, M. Paisi Jan 2020

Homelessness On The Curriculum?, R. Witton, M. Paisi

Peninsula Dental School

No abstract provided.


Evaluation Of An Orthotic Intervention For The Management Of Pregnancy Related Pelvic Girdle Pain (Pgp), Lee Cameron Jan 2020

Evaluation Of An Orthotic Intervention For The Management Of Pregnancy Related Pelvic Girdle Pain (Pgp), Lee Cameron

Other Faculty of Health Theses

The overall aim of the thesis was to evaluate the effectiveness of a novel orthotic intervention, a customised Dynamic Elastomeric Fabric Orthosis (DEFO), in the management of both antenatal and post-partum pelvic girdle pain (PGP). In the first instance the fabric, from which the DEFO was constructed, underwent testing to determine if the different colour fabrics available possessed the same underlying fabric stiffness and elastic hysteresis to ensure that each orthotic was standardised. Laboratory testing identified significant differences in both fabric stiffness and elastic hysteresis, between colours. The findings of this study enabled standardisation of the intervention by using a …


The Unequal Variance Signal-Detection Model Of Recognition Memory: Investigating The Encoding Variability Hypothesis, Rory W. Spanton, Christopher J. Berry Jan 2020

The Unequal Variance Signal-Detection Model Of Recognition Memory: Investigating The Encoding Variability Hypothesis, Rory W. Spanton, Christopher J. Berry

School of Psychology

Despite the unequal variance signal-detection (UVSD) model’s prominence as a model of recognition memory, a psychological explanation for the unequal variance assumption has yet to be verified. According to the encoding variability hypothesis, old item memory strength variance (σo) is greater than that of new items because items are incremented by variable, rather than fixed, amounts of strength at encoding. Conditions that increase encoding variability should therefore result in greater estimates of σo. We conducted three experiments to test this prediction. In Experiment 1, encoding variability was manipulated by presenting items for a fixed or variable (normally distributed) duration at …


Advanced Glycation End Products As A Biomarker For Accelerated Ocular Ageing And Glaucoma, Leanne Smewing Jan 2020

Advanced Glycation End Products As A Biomarker For Accelerated Ocular Ageing And Glaucoma, Leanne Smewing

Other Faculty of Health Theses

Advanced glycation end products (AGEs) have a large impact on the healthy ageing population and those diagnosed with pathology. Studies have linked AGEs to glaucomatous optic neuropathy, however there is little consensus on the role AGEs play in glaucoma development. Furthermore, it is known that diet is an exogenous source of AGEs, however it is not clear how dietary AGE (dAGE) influences tissue-bound levels in the body. The overarching theme of this thesis was to assess the impact of AGE level, measured both through diet and tissue-bound levels in the skin (skin autofluoresence, SAF), on retinal vessels and the cornea …


Enhancing Grit In Elite Athletes Through Functional Imagery Training, Jon Rhodes Jan 2020

Enhancing Grit In Elite Athletes Through Functional Imagery Training, Jon Rhodes

Other Faculty of Health Theses

Grit has been researched across a wide variety of domains with negative correlations to drop out rates and positive associations to performance. However, there has been little to empirically change character through interventions, and even fewer in sport. A total of six studies are presented through a mixed-method approach to initially gain an understanding how grit is created, and the processes involved in developing the trait (Studies One and Two). From the phenomenological findings, a bespoke Functional Imagery Training (FIT) intervention is initially tailored to athletes and delivered (Study Three). With ceiling effects present from our performance athletes (and those …


Influenza A Virus Infection And Innate Immunity In An Established Murine Alveolar-Like Macrophage Model, Connor Wood Jan 2020

Influenza A Virus Infection And Innate Immunity In An Established Murine Alveolar-Like Macrophage Model, Connor Wood

Other Faculty of Health Theses

Influenza is both a seasonal and occasional pandemic respiratory infection in humans, with the most vulnerable of society at the highest risk. With vaccine efficiency dropping and resistance against treatments, better understanding of the host-viral interactions is required to find novel therapy targets. Much of the current understanding for the host-viral interactions comes from epithelial cells or imperfect macrophage models. Alveolar macrophages (AMs) are crucial in the first stages of infection, but due to limited availability, true functional experiments have been impossible. By using the novel AM-like macrophage, Max Plank Institute (MPI) cells, which are available in practically unlimited numbers, …


Letter On “Protection By Exclusion? The (Lack Of) Inclusion Of Adults Who Lack Capacity To Consent To Research In Clinical Trials In The Uk”, Sarah Griffiths, Lorna Manger, Rebecca Chapman, Lauren Weston, Ian Sherriff, Cath Quinn, Paul Clarkson, Caroline Sutcliffe, Karen Davies, Richard Byng Jan 2020

Letter On “Protection By Exclusion? The (Lack Of) Inclusion Of Adults Who Lack Capacity To Consent To Research In Clinical Trials In The Uk”, Sarah Griffiths, Lorna Manger, Rebecca Chapman, Lauren Weston, Ian Sherriff, Cath Quinn, Paul Clarkson, Caroline Sutcliffe, Karen Davies, Richard Byng

Peninsula Medical School

Dear editors, We read with interest the recent article regarding the lack of inclusion of people who lack capacity in trials: ‘Protection by exclusion? The (lack of) inclusion of adults who lack capacity to consent in clinical trials in the UK’. As the authors so eloquently spotlight, those without capacity in many population groups are those who are likely to be most vulnerable to frailty, comorbidities and isolation. Their exclusion from research significantly limits the specific evidence base for their care. As a research team developing and evaluating a Dementia Support Worker intervention based in primary care, we appreciate the …


Aging Predicts Decline In Explicit And Implicit Memory: A Life-Span Study, Emma V. Ward, Christopher J. Berry, David R. Shanks, Petter L. Moller, Enida Czsiser Jan 2020

Aging Predicts Decline In Explicit And Implicit Memory: A Life-Span Study, Emma V. Ward, Christopher J. Berry, David R. Shanks, Petter L. Moller, Enida Czsiser

School of Psychology

Explicit memory declines with age, but age effects on implicit memory are debated. This issue is important because if implicit memory is age invariant, it may support effective interventions in individuals experiencing memory decline. In this study, we overcame several methodological issues in past research to clarify age effects on implicit memory (priming) and their relationship to explicit memory (recognition, source memory). We (a) recruited a large life-span sample of participants ( N = 1,072) during a residency at the Science Museum in London, (b) employed an implicit task that was unaffected by explicit contamination, and (c) systematically manipulated attention …


Epidermicin Ni01 And Human Β-Defensin 2 As Modulators Of Macrophage Subset Responses, Barbara Durante Jan 2020

Epidermicin Ni01 And Human Β-Defensin 2 As Modulators Of Macrophage Subset Responses, Barbara Durante

Other Faculty of Health Theses

Antimicrobial peptides (AMPs) and host defence peptides (HDPs) have been extensively investigated for their antimicrobial activity and evidence suggests that they can also modulate the host immune system. However, little is known about their effects on macrophages, a key cell population in inflammatory responses that mediates communication between innate and adaptive immunity. Macrophages are a pleiotropic cell population composed of different subsets that orchestrate diverse stages of inflammation with roles ranging from pro- to anti-inflammatory and thus, targets for immunomodulation in different diseases. Here, THP-1-derived M1- and M2-like cells (pro- and anti-inflammatory respectively) under stimulation of TLR4 by LPS were …


Birth Trauma From The Perspective Of Perinatal Counsellors. A Mini Focus Group Study, G Baptie, E Januario, A Norman Jan 2020

Birth Trauma From The Perspective Of Perinatal Counsellors. A Mini Focus Group Study, G Baptie, E Januario, A Norman

School of Psychology

One in five women in the UK develop mental health problems during pregnancy or in the first year after childbirth. ‘Birth trauma’ is a common birth-related mental health issue which stems from perceiving childbirth as a traumatic experience; the term ‘birth trauma’ also encompasses living with and experiencing the accompanying symptoms of trauma after childbirth. A mini focus group study was conducted with two experienced perinatal counsellors to discuss their experiences working with parents struggling with birth trauma. Analysis of the focus group revealed five key themes: the complexity of birth trauma; the power of communication; changes in culture; falling …


Remimazolam For Anaesthesia Or Sedation, J. Robert Sneyd, Ann E. Rigby-Jones Jan 2020

Remimazolam For Anaesthesia Or Sedation, J. Robert Sneyd, Ann E. Rigby-Jones

Peninsula Medical School

Purpose of review Anaesthesia and sedation are ubiquitous in contemporary medical practice. Developments in anaesthetic pharmacology are targeted on reducing physiological disturbance whilst maintaining or improving titrateability, recovery profile and patient experience. Remimazolam is a new short-acting benzodiazepine in the final stages of clinical development. Recent findings Clinical experience with remimazolam comprises volunteer studies and a limited number of clinical investigations. In addition, laboratory investigations explore the implications of its 'soft drug' pharmacology. Summary Remimazolam provides effective procedural sedation with superior success rates and recovery profile when compared to midazolam. Comparisons with propofol are required. Preliminary studies suggest potential for …