Digital Commons Network^™

Predictors Of Gestational Weight Gain In A Low-Income Hispanic Population: Sociodemographic Characteristics, Health Behaviors, And Psychosocial Stressors, C. D. Dolin, R. S. Gross, A. L. Deierlein, L. T. Berube, M. Katzow, Y. Yaghoubian, S. G. Brubaker, M. J. Messito

Journal Articles

No abstract provided.

Insulin Resistance And Cancer-Specific And All-Cause Mortality In Postmenopausal Women: The Women's Health Initiative, K. Pan, R. A. Nelson, J. Wactawski-Wende, D. J. Lee, J. A. Manson, A. K. Aragaki, J. E. Mortimer, L. S. Phillips, G. Y. Ho, R. T. Chlebowski, +6 Additional Authors

Journal Articles

© The Author(s) 2019. Published by Oxford University Press. All rights reserved. For permissions, please email: [email protected]. BACKGROUND: Insulin resistance has been proposed as a mediator of the increased cancer incidence and mortality associated with obesity. However, prior studies included limited cancer deaths and had inconsistent findings. Therefore, we evaluated insulin resistance and cancer-specific and all-cause mortality in postmenopausal women participating in the Women's Health Initiative (WHI). METHODS: Eligible were a subsample of 22 837 WHI participants aged 50-79 years enrolled at 40 US clinical centers from 1993 to 1998 who had baseline fasting glucose and insulin levels. Baseline insulin …

Racial Disparity In Pregnancy Risks And Complications In The Us: Temporal Changes During 2007-2018, E. Bornstein, Y. Eliner, F. A. Chervenak, A. Grunebaum

Journal Articles

No abstract provided.

A Modified Delphi Study To Prioritize Content For A Simulation-Based Pediatric Curriculum For Emergency Medicine Residency Training Programs, J. Mitzman, I. Bank, R. A. Burns, M. C. Nguyen, P. Zaveri, M. J. Falk, M. Madhok, A. Dietrich, F. M. Bullaro, M. Auerbach, +9 Additional Authors

Journal Articles

© 2019 by the Society for Academic Emergency Medicine Objectives: Pediatric training is an essential component of emergency medicine (EM) residency. The heterogeneity of pediatric experiences poses a significant challenge to training programs. A national simulation curriculum can assist in providing a standardized foundation of pediatric training experience to all EM trainees. Previously, a consensus-derived set of content for a pediatric curriculum for EM was published. This study aimed to prioritize that content to establish a pediatric simulation-based curriculum for all EM residency programs. Methods: Seventy-three participants were recruited to participate in a three-round modified Delphi project from 10 stakeholder …

Locked-In With Covid-19, A. Avula, A. Gill, R. Nassar, K. Nalleballe, S. Siddamreddy, M. Chalhoub

Journal Articles

© 2020 Elsevier Ltd Coronavirus Disease 2019 (COVID-19) can be associated with various neurological manifestations including acute strokes. Hyper acute diagnosis and treatment are key factors which decrease mortality and morbidity in stroke patients. The COVID-19 pandemic has introduced a great strain on the healthcare system, and as a result clinicians are facing several barriers in diagnosing and treating strokes. Delayed presentation of strokes is a problem as some in the general population defer the decision to seek immediate medical attention fearing contracting the virus. Also playing a role is the paucity of healthcare professionals available during a pandemic. Recent …

Nebulized In-Line Endotracheal Dornase Alfa And Albuterol Administered To Mechanically Ventilated Covid-19 Patients: A Case Series., A. G. Weber, A. S. Chau, M. Egeblad, B. J. Barnes, T. Janowitz

Journal Articles

Background Mechanically ventilated patients with coronavirus disease 2019 (COVID-19) have a mortality of 24-53%, in part due to distal mucopurulent secretions interfering with ventilation. Dornase alfa is recombinant human DNase 1 and digests DNA in mucoid sputum. Nebulized dornase alfa is FDA-approved for cystic fibrosis treatment. DNA from neutrophil extracellular traps (NETs) contributes to the viscosity of mucopurulent secretions. NETs are found in the serum of patients with severe COVID-19, and targeting NETs reduces mortality in animal models of acute respiratory distress syndrome (ARDS). Thus, dornase alfa may be beneficial to patients with severe COVID-19, acting as a mucolytic and …

Challenges In Abdominal Organ Transplantation During The Covid-19 Pandemic, S. M. Esagian, I. A. Ziogas, D. Giannis, M. H. Hayat, N. Elias, G. Tsoulfas

Journal Articles

© Copyright © 2020 Esagian, Ziogas, Giannis, Hayat, Elias and Tsoulfas. As the coronavirus disease 2019 (COVID-19) outbreak has rapidly evolved into a global pandemic, abdominal organ transplantation programs are currently facing multiple challenges. Transplant candidates and recipients are considered high-risk populations for severe disease and death due to COVID-19 as a result of their numerous underlying comorbidities, advanced age and impaired immune function. Emerging reports of atypical and delayed clinical presentations in these patients generate further concerns for widespread disease transmission to medical personnel and the community. The striking similarities between COVID-19 and other outbreaks that took place over …

Presenting Characteristics, Comorbidities, And Outcomes Among 5700 Patients Hospitalized With Covid-19 In The New York City Area, S Richardson, Js Hirsch, M Narasimhan, Jm Crawford, T Mcginn, Kw Davidson, Northwell Covid-19 Research Consortium

Journal Articles

No abstract provided.

Supplemental Schedules For The Year Ended June 30, 2020, Clemson University Controller's Office

Supplemental Schedules

No abstract provided.

The Inim Spring 2020, Nova Southeastern University

INIM Newsletters

No abstract provided.

Survival Of A Serotype 4b Strain And A Serotype 1/2a Strain Of Listeria T Monocytogenes, Isolated From A Stone Fruit Outbreak Investigation, On Whole Stone Fruit At 4 °C, Antonio J. De Jesus, Ishani Sheth, Hee Jin Kwon, Zhujun Gao, Jessica Palmer, Minji Hur, Thomas S. Hammack, Dumitru Macarisin, Yi Chen

United States Food and Drug Administration: Publications

In the summer of 2014, a multistate outbreak of listeriosis associated with contaminated stone fruit (peach and nectarine) was reported. A serotype 4b variant Listeria monocytogenes (Lm) strain of singleton Sequence Type (ST) 382 was isolated from clinical samples and stone fruit associated with the outbreak. A serotype 1/2b Lm strain of ST5, Clonal Complex 5 was isolated only from outbreak-associated stone fruit, not from clinical samples. Here we investigated the fate of the serotype 4b and 1/2b strains, at two inoculation levels (high level at 3.7 logCFU/fruit and low level at 2.7 logCFU/fruit), on the surfaces of white peach, …

Adult Perceptions Of The Relative Harm Of Tobacco Products And Subsequent T Tobacco Product Use: Longitudinal Findings From Waves 1 And 2 Of The Population Assessment Of Tobacco And Health (Path) Study, Tara Elton-Marshall, Pete Driezen, Geoffrey T. Fong, K. Michael Cummings, Alexander Persoskie, Olivia Wackowski, Kelvin Choi, Annette Kaufman, David Strong, Shannon Gravely, Kristie Kristie, Jonathan Kwan, Maansi Bansal-Travers, Mark Travers, Andrew Hyland

United States Food and Drug Administration: Publications

Objectives: To examine: (1) How perceptions of harm for seven non-cigarette tobacco products predict sub- sequent use; (2) How change in use is associated with changes in perceptions of product harm; (3) Whether sociodemographic variables moderate the association between perceptions and use.

Methods: Data are from the adult sample (18+) of the Population Assessment of Tobacco and Health (PATH) Study, a nationally representative longitudinal cohort survey conducted September 2013-December 2014 (Wave 1 (W1) n = 32,320) and October 2014-October 2015 (Wave 2 (W2) n = 28,362).

Results: Wave 1 users and non-users of e-cigarettes, filtered cigars, cigarillos, and pipes, who …

An Evaluation Of The Usda's Policy To Reduce Listeria Illnesses In Ready‐To‐Eat Meat And Poultry Products, Travis Minor, Matt Parrett

United States Food and Drug Administration: Publications

Using 1998–2008 data collected by the Centers for Disease Control and Prevention on foodborne illnesses and outbreaks, we examine the economic impact of the United States Department of Agriculture's proposed and final rules to reduce the incidence of Listeria monocytogenes (Lm) in ready‐to‐ eat meat and poultry products. Using a difference‐in‐ differences approach, we find that these rules together reduced meat‐related Lm illnesses by about 60 per year, which we attribute to reductions in both the number and average size of meat‐related Lm outbreaks. We then monetize this illness reduction using an underreporting and underdiagnosis multiplier of 2.3 and an …

Genomics-Based Re-Examination Of The Taxonomy And Phylogeny Of Human And Simian Mastadenoviruses: An Evolving Whole Genomes Approach, Revealing Putative Zoonosis, Anthroponosis, And Amphizoonosis, June Kang, Ashrafali Mohamed Ismail, Shoaleh Dehghan, Jaya Rajaiya, Marc W. Allard, Haw Chuan Lim, David W. Dyer, James Chodosh, Donald Seto

United States Food and Drug Administration: Publications

With the advent of high-resolution and cost-effective genomics and bioinformatics tools and methods contributing to a large database of both human (HAdV) and simian (SAdV) adenoviruses, a genomics-based re-evaluation of their taxonomy is warranted. Interest in these particular adenoviruses is growing in part due to the applications of both in gene transfer protocols, including gene therapy and vaccines, as well in oncolytic protocols. In particular, the re-evaluation of SAdVs as appropriate vectors in humans is important as zoonosis precludes the assumption that human immune system may be na€ıve to these vectors. Additionally, as impor- tant pathogens, adenoviruses are a model …

The Impact Of The Abuse-Deterrent Reformulation Of Extended-Release T Oxycontin On Prescription Pain Reliever Misuse And Heroin Initiation, Carolyn Wolff, William N. Dowd, Mir M. Ali, Chandler Mcclellan, Angelica Meinhofer, Lukas Glos, Ryan Mutter, Matthew Rosenberg, Andreas Schikc

United States Food and Drug Administration: Publications

The introduction of abuse-deterrent OxyContin in 2010 was intended to reduce its misuse by making it more tamper resistant. However, some studies have suggested that this reformulation might have had unintended consequences, such as increases in heroin-related deaths. We used the 2005–2014 cross-sectional U.S. National Survey on Drug Use and Health to explore the impact of this reformulation on intermediate outcomes that precede heroin-related deaths for individuals with a history of OxyContin misuse. Our study sample consisted of adults who misused any prescription pain reliever prior to the reformulation of OxyContin (n = 81,400). Those who misused OxyContin prior to …

Development Of A Nicotinic Acetylcholine Receptor Nachr Α7 Binding Activity Prediction Model, Sugunadevi Sakkiah, Carmine Leggett, Bohu Pan, Wenjing Guo, Luis G. Valerio Jr., Huixiao Hong

United States Food and Drug Administration: Publications

Despite the well-known adverse health effects associated with tobacco use, addiction to nicotine found in tobacco products causes difficulty in quitting among users. Nicotinic acetylcholine receptors (nAChRs) are the physiological targets of nicotine and facilitate addiction to tobacco products. The nAChR-α7 subtype plays an important role in addiction; therefore, predicting the binding activity of tobacco constituents to nAChR-α7 is an important component for assessing addictive potential of tobacco constituents. We developed an α7 binding activity prediction model based on a large training data set of 843 chemicals with human α7 binding activity data extracted from PubChem and ChEMBL. The model …

Male Figural Rating Scales: A Critical Review Of The Literature, Daniel Talbot, John Cass, Evelyn Smith

Sciences Papers and Journal Articles

Figural rating scales are tools used to measure male body dissatisfaction. The present review aimed to examine the design and psychometric properties of male figural rating scales and make recommendations based on findings. Relevant databases were systematically searched for studies that had developed and validated male figural rating scales. Twenty studies were included in this review. Figural rating scales differed in terms of the number of images represented and type of stimuli used (hand-drawn silhouettes, hand-drawn figures, computer-rendered figures, and photograph figures). Reliability and validity evidence varied greatly in strength across all scales. Four of the 20 scales included a …

Partial Adjustment Of Self-Reported Alcohol Consumption In The National Health And Nutrition Examination Survey: A Zero Inefficiency Stochastic Frontier Analysis, Isabella A. Yerby

Honors Undergraduate Theses

Alcohol consumption is likely underreported in the National Health and Nutrition Examination Survey. The problem, common among most self-reported data, stems from social desirability bias. As a result of this bias, the true level of alcohol consumption, specifically heavy episodic drinking, or binge drinking, is undercounted. By applying zero inefficiency stochastic frontier analysis, we adjust for the inefficiency caused by survey participants underreporting their alcohol consumption. This paper serves to partially correct the estimates of heavy episodic drinking and to serve as an example that stochastic frontier analysis can be used outside of its standard application to correct underreported and …

Apoptosis And Necrosis Drive Muscle Fiber Loss In Lipin1 Deficient Skeletal Muscle, Sandhya Ramani Sattiraju

Browse all Theses and Dissertations

Mutations in lipin1 are suggested to be a common cause of massive rhabdomyolysis episodes in children, however, the molecular mechanism involved in the regulation of myofiber death by lipin1 is not known. In this study, we utilized the skeletal muscle from cell-type-specific lipin1 knockout (Lipin1Myf5cKO) mice to define cell death pathways involved in lipin1 deficient muscles. We observed a significant increase in centrally nucleated fibers and embryonic myosin heavy chain (EMyHC)-positive regenerating fibers in Lipin1Myf5cKO mice compared to wild-type (WT) mice, indicating an increased cycle of degeneration and regeneration in lipin1 deficient muscles. Lipin1 deficient muscles had significantly elevated pro-apoptotic …

Students’ Knowledge Of Alzheimer’S Disease, D'Anna Helms

Nursing Theses and Capstone Projects

Preparing nursing students to care for the ever-growing aging population with memory impairment is vital. This research study aimed to determine the prevalence of knowledge of Alzheimer’s disease (AD) among Baccalaureate nursing students. A descriptive correlational design was used to determine the prevalence of AD knowledge among juniors in an Adult I course and seniors in a Mental Health nursing course. A cross-sectional design was used to collect data using the Alzheimer’s Disease Knowledge Scale (ADKS). A convenience sample of 63 student cohorts completed the survey. Results indicated that students were aware that AD is a form of dementia; however, …

Development Of Cut-Points For Determining Activity Intensity From A Wrist-Worn Actigraph Accelerometer In Free-Living Adults, Alexande H.K. Montoye, Kimberly A. Clevenger, Karin A. Pfeiffer, Michael B. Nelson, Joshua M. Bock, Mary T. Imboden, Leonard A. Kaminsky

Faculty Publications - Department of Kinesiology

Despite recent popularity of wrist-worn accelerometers for assessing free-living physical behaviours, there is a lack of user-friendly methods to characterize physical activity from a wrist-worn ActiGraph accelerometer. Participants in this study completed a laboratory protocol and/or 3–8 hours of directly observed free-living (criterion measure of activity intensity) while wearing ActiGraph GT9X Link accel- erometers on the right hip and non-dominant wrist. All laboratory data (n = 36) and 11 participants’ free- living data were used to develop vector magnitude count cut-points (counts/min) for activity intensity for the wrist-worn accelerometer, and 12 participants’ free-living data were used to cross-validate cut-point accuracy. …

Bathypelagic Ocean Waters, Christy Linardich, Tracey Sutton, Imants G. Priede, David A. Keith

Marine & Environmental Sciences Faculty Books and Book Chapters

No abstract provided.

Mesopelagic Ocean Waters, Kate E. Watermeyer, Eduard J. Gregr, Ryan R. Rykaczewski, Imants G. Priede, Tracey Sutton, David A. Keith

Marine & Environmental Sciences Faculty Books and Book Chapters

No abstract provided.

Niu Working Papers 2019-2020, Northern Illinois University

Working Papers

No abstract provided.

The Effects Of Caffeine On Early Second Half Sprint Performance In Ncaa Diii Women’S Soccer Players, David J. Granniss, Jessica W. Chow, Daniel A. Jaffe, Kristin M. Cannon, Jessica C. Brown, Deborah Vanlangen, Charity A. Byrum

Department of Exercise Science Faculty Publications

Objective

The purpose of this study was to examine the effects of caffeine on early second half sprint performance in 21 NCAA DIII women’s soccer players. The caffeine dosage attempted to approximate a liquid dosage many student athletes typically consume.

Design

In a randomized double blind repeated measures design, subjects began the protocol after ingestion of caplets containing 3 mg^.kg^-1 of caffeine (CAF) and after ingestion of placebo (PLA) caplets. Pre-game, warm-up, and first half conditions were designed to maximize external validity.

Methods

An adapted version of the Loughborough Intermittent Shuttle Test was applied to replicate first …

Postpartum Depression In Military Mothers:Active Duty And Partners Of Active Duty Service Members, Amanda Willis

Master of Science in Nursing Theses and Projects

Postpartum depression (PPD) is the most common complication of pregnancy. Active duty mothers and mothers with active duty spouses have a unique risk factor, deployment. Military mothers may receive PPD education prenatally and during postpartum visits if necessary. This project created a postpartum depression video that was mandatory for mothers to watch before they were discharged from the postpartum unit after the delivery of their baby. Early education and treatment are the key to managing PPD in all mothers. The mothers were surveyed at their postpartum office visits to evaluate effectiveness of video.

Preparing The Nurse Aide I Student For The Workplace: Combating Burnout And Compassion Fatigue, Patrice Staley

Master of Science in Nursing Theses and Projects

Abstract not available

2020 Year In Review: A Celebration Of Early Childhood In The Granite State, Nh Preschool Development Grant

Preschool Development Grant

No abstract provided.

Planting Date, Cultivar, Seed Treatment, And Seeding Rate Effects On Soybean Growth And Yield, Thandiwe Nleya, Matthew Schutte, David Clay, Graig Reicks, Nathan Mueller

Agronomy, Horticulture and Plant Science Faculty Publications

Soybean [Glycine max (L.) Merr.] yield is a function of many factors including genetic attributes of the cultivar, environmental conditions, and management practices. Temporally variable weather patterns in North America, especially in the northern Great Plains, have resulted in the re-examination of how spring production practices interact with the environmental conditions to influence yield. This study evaluated the impact of four plantings dates, four seeding rates, and two soybean maturity groups (MGs) using treated and untreated (control) seed on soybean growth, seed yield, and composition. The study was conducted at Volga, SD, in 2014, 2015, and 2016. The planting …

Impact Of Cardiologist Intervention On Guideline-Directed Use Of Statin Therapy, M. Cassagnol, O. Hai, S. A. Sherali, K. D'Angelo, D. Bass, R. Zeltser, A. N. Makaryus

Journal Articles

© The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved. BACKGROUND Statins have an important and well-established role in the prevention of atherosclerotic cardiovascular disease (ASCVD). However, several studies have reported widespread underuse of statins in various practice settings and populations. Review of relevant literature reveals opportunities for improvement in the implementation of guideline-directed statin therapy (GDST). AIM To examine the impact of cardiologist intervention on the use of GDST in the ambulatory setting. METHODS Patients with at least one encounter at the adult Internal Medicine Clinic (IMC) and/or Cardiology Clinic (CC), who had an available serum …