Digital Commons Network^™

Presence Of Dirofilaria Immitis In Mosquitoes In Southeastern Georgia, Angelica C. Tumminello

Honors College Theses

Canine heartworm disease is caused by the filarial nematode Dirofilaria immitis, which is transmitted by at least 25 known species of mosquito vectors. This study sought to understand which species of mosquitoes are present in Bulloch County, Georgia, and which species are transmitting canine heartworm disease. This study also investigated whether particular canine demographics correlated with a greater risk of heartworm disease. Surveillance of mosquitoes was conducted in known heartworm-positive canine locations using traditional gravid trapping and vacuum sampling. Mosquito samples were frozen until deemed inactive, then identified by species and sex. The mosquitoes were then either dissected under …

The Society For Immunotherapy Of Cancer Perspective On Regulation Of Interleukin-6 Signaling In Covid-19-Related Systemic Inflammatory Response, Fernanda I. Arnaldez, Steven J. O'Day, Charles G. Drake, Bernard A Fox, Bingqing Fu, Walter Urba, Vincenzo Montesarchio, Jeffrey S. Weber, Haiming Wei, Jon M. Wigginton, Paolo Antonio Ascierto

Articles, Abstracts, and Reports

The pandemic caused by the novel coronavirus SARS-CoV-2 has placed an unprecedented burden on healthcare systems around the world. In patients who experience severe disease, acute respiratory distress is often accompanied by a pathological immune reaction, sometimes referred to as ‘cytokine storm’. One hallmark feature of the profound inflammatory state seen in patients with COVID-19 who succumb to pneumonia and hypoxia is marked elevation of serum cytokines, especially interferon gamma, tumor necrosis factor alpha, interleukin 17 (IL-17), interleukin 8 (IL-8) and interleukin 6 (IL-6). Initial experience from the outbreaks in Italy, China and the USA has anecdotally demonstrated improved outcomes …

Severe Covid-19 Infection In Pregnancy Requiring Intubation Without Preterm Delivery: A Case Report, Leah Hong, Nicolina Smith, Madhurima Keerthy, Monica Lee-Griffith, Robyn Garcia, Majid Shaman, Gregory Goyert

Obstetrics, Gynecology and Women's Health Services Articles

Background: Coronavirus-2019 (COVID-19) is a global health crisis, but there is limited guidance for the critical care management of pregnant patients experiencing respiratory collapse. We describe our management of a peri-viable pregnant patient requiring intubation; discussion includes pharmacologic interventions, mechanical ventilation adjustments, and consideration of fetal interventions, including delivery timing.

Case: A 36-year-old, gravida 2, para 1 woman positive for COVID-19 at 23 weeks of gestation with severe disease required admission to the intensive care unit and intubation. She completed 5 days of hydroxychloroquine and 7 days of prednisone. She was successfully intubated after 8 days and discharged home in …

Novel Role Of Endothelial Derived Exosomal Hspa12b In Regulating Macrophage Inflammatory Responses In Polymicrobial Sepsis, Fei Tu, Xiaohui Wang, Xia Zhang, Tuanzhu Ha, Yana Wang, Min Fan, Kun Yang, P. Spencer Gill, Tammy R. Ozment, Yuan Dai, Li Liu, David L. Williams, Chuanfu Li

ETSU Faculty Works

Endothelial cell dysfunction contributes to sepsis induced initiate immune response and the infiltration of immune cells into organs, resulting in organ injury. Heat shock protein A12B (HSPA12B) is predominantly expressed in endothelial cells. The present study investigated whether endothelial HSPA12B could regulate macrophage pro-inflammatory response during sepsis. Wild type (WT) and endothelial cell-specific HSPA12B deficient (HSPA12B–/–) mice were subjected to CLP sepsis. Mortality and cardiac function were monitored. Higher mortality, worsened cardiac dysfunction, and greater infiltrated macrophages in the myocardium and spleen were observed in HSPA12B–/– septic mice compared with the WT septic mice. The serum levels of TNF-α and …

Bibliometric Analysis Of The Literature In The Field Of Coronavirus, Jagannathan Ramakrishnan Dr, Govindan Ravi Sankar Dr, Kotti Thavamani Dr

Library Philosophy and Practice (e-journal)

This paper presents a bibliometric analysis of the literature in the field of Coronavirus in MEDLINE data which has been covered in PubMed. The study period has been selected from the year 2000 to 2019. It is noticed that 10700 records available in the field of Coronavirus. It has been found that 41.71% of records are Research Support, Non U.S. Gov't, and 30.18% are Journal Articles. The United States is the major publisher in the field of Coronavirus followed by England, Netherlands, China, etc. It shows that 95.14% of the total records were in the English language. Relative Growth Rate …

Public Perspectives And Media Reporting Of Wolf Reintroduction In Colorado, Rebecca Niemiec, Richard E.W. Berl, Mireille Gonzalez, Tara Teel, Cassiopeia Camara, Matthew Collins, Jonathan Salerno, Kevin Crooks, Courtney Schultz, Stewart Breck, Dana Hoag

United States Department of Agriculture Wildlife Services: Staff Publications

In the state of Colorado, a citizen ballot initiative to reintroduce gray wolves (Canis lupus) is eliciting polarization and conflict among multiple stakeholder and interest groups. Given this complex social landscape, we examined the social context surrounding wolf reintroduction in Colorado as of 2019. We used an online survey of 734 Coloradans representative in terms of age and gender, and we sampled from different regions across the state, to examine public beliefs and attitudes related to wolf reintroduction and various wolf management options. We also conducted a content analysis of media coverage on potential wolf reintroduction in 10 major daily …

Shutdown Policies And Worldwide Conflict, Nicolas Berman, Mathieu Couttenier, Nathalie Monnet, Rohit Ticku

ESI Working Papers

We provide real-time evidence on the impact of Covid-19 restrictions policies on conflicts globally. We use daily information on conflict events and government policy responses to limit the spread of coronavirus to study how conflict levels vary following shutdown and lockdown policies. We use the staggered implementation of restriction policies across countries to identify their effect on conflict incidence and intensity. Our results show that imposing a nation-wide shutdown reduces the likelihood of daily conflict by around 9 percentage points. The reduction is driven by a drop in the incidence of battles, protests and violence against civilians. Across actors the …

Trade And Security Among The Ruins, J. Benton Heath

Duke Journal of Comparative & International Law

The collision of trade and security interests is taking place today in an increasingly fragmented landscape. Governments’ conceptions of their own vital interests are undergoing a rapid transformation as the concept of “national security” expands to encompass issues such as national industrial policy, cybersecurity, and responses to climate change and pandemic disease. At the same time, the system for settling trade disputes is being pulled apart by competing tendencies toward legalism and deformalization. Last year, a landmark decision suggested that international adjudicators could oversee this clash between security and trade, deciding which security interests can override trade rules and which …

2020-05-07 Daily Unm Global Health Covid-19 Briefing, Christophe G. Lambert, Shawn Stoicu, Ingrid Hendrix, Lori D. Sloane, Mari Anixter, Anastasiya Nestsiarovich, Praveen Kumar, Nicolas Lauve, Emma Wolinsky, Ryen Ormesher, Lauren Tagliaferro Epler, Timothy Campbell, Jenny Situ, Jennifer Thompson, Ryota Shimada, Ariel Hurwitz, Avanika Mahajan, Sandra Boettcher, Alexandra Yingling, Perez Olewe, Cristian Bologa, Gregory Mertz, Krisitne Tollestrup, Orrin Myers, Douglas J. Perkins

HSC Covid 19 Briefings

Executive Summary:

NM cases. Gallup shutdown extended. Gallup hospital crisis. NM assisted living testing. University student financial relief. FDA fraudulent products. Trump/Pence test negative. India displaced repatriated. Use facemasks. Facemasks cause skin damage. PPE protocol. Michigan reopens. Illegal drug prices up. Failing masks from China. Distribution of remdesivir. CDC PPE video. Low German R0. Stay-at-home lowers Rt. Detention facility epidemiology. Saliva transmission. Healthcare informatics shortcomings. Resource allocation ethics. Uninsured drug discounts. Safer food delivery. Bat coronavirus grant axed. Dispelling common misinformation. Recommendations on managing cardiac arrest, cardiac electrotherapy and electrophysiology, hematologic malignancy, ophthalmologic screening and procedures, the use of ACEIs …

2020-05-07 A Message From Chancellor Roth, Paul B. Roth

HSC Messages from the Chancellor

No abstract provided.

Individualized Mosaics Of Microbial Strains Transfer From The Maternal To The Infant Gut, Jeff Hansen

Browse All News

No abstract provided.

Symposium: Pandemics And The Constitution: Positive Constitutionalism In A Pandemic: Demanding Responsibility From The Trump Administration, Ruthann Robson

ConLawNOW

We have become accustomed to conceiving of our constitutional rights as affording protection only against government infringement, but not as granting us any positive rights to claim government protection or action. The circumstances surrounding the COVID-19 pandemic should make us question this reflexive resort to negative constitutionalism. The numerous failures of the present federal Administration to ameliorate and address the pandemic are startling. Even under current doctrinal limits of negative rights, the Administration’s failures should give rise to individual constitutional claims. Most importantly, we should reorient our constitutional frameworks, theories, and doctrines toward recognition of positive rights to health and …

Symposium: Pandemics And The Constitution: Why The Special Needs Doctrine Is The Most Appropriate Fourth Amendment Theory For Justifying Police Stops To Enforce Covid-19 Stay-At-Home Orders, Henry F. Fradella

ConLawNOW

Despite the fact that the steps the federal and state governments take to curtail the spread of the viral infection are presumably taken in the best interest of public health, governmental actions and actors must comply with the U.S. Constitution even during a pandemic. Some public health measures, such as stay-at-home orders, restrict the exercise of personal freedoms ranging from the rights to travel and freely associate to the ability to gather in places of worship for religious services. This Essay explores several completing doctrines that might justify the authority of law enforcement to stop people who are out of …

Numerical Simulation To The Fitzhugh-Nagumo Model With Strong Reaction, Hongsong Feng

Theses and Dissertations

The Fitzhugh-Nagumo model is a mathematical model derived from the simulation of propagating pulses in multicellular organisms. Since its creation, this model has drawn great attentions from academics and industry. To better understand the properties underlying this system, suitable numerical methods are needed to study it. In this thesis, numerical methods including the finite difference method, the finite element method, and the least-squares finite element method are applied to approximate its traveling wave solutions. In particular, since the FitzHugh-Nagumo model with strong reaction has a significant role in application, appropriate numerical scheme is designed to study it. Consistency and stability …

The Sir Models, Their Applications, And Approximations Of Their Rates, Christopher Cano

Mathematics Senior Capstone Papers

The SIR (Susceptible-Infected-Recovered) models are used to help predict the spread of diseases. The goals of this paper are: elaborating on the methods of approximating the recovery rate, infection rate, and loss of immunity rate, comparing the SIR models with these approximation methods to real world data, and determining the most accurate combination of the approximation methods for each SIR model. There are several SIR models such as the Kermack-McKendrick, SIRS, and SI models that are designed for specific diseases. Understanding the parameters of these models will assist us in maximizing their accuracy. For example, there is no explicit formula …

2020-05-06_Michiganoverview_Covidsymptoms, Michigan Department Of Health & Human Services

Michigan COVID-19 Syndromic Surveillance System Data

The Syndromic Surveillance System Data report was obtained from Michigan's COVID-19 dashboard, from under the link "​Coronavirus Symptoms": https://www.michigan.gov/coronavirus. Data was compiled by the Michigan Department of Health and Human Services (MDHHS). The information was updated daily.

Syndromic Surveillance System data is obtained from approximately 183 facilities participating in syndromic surveillance (132 Emergency Departments (ED), 51 Urgent Cares) across the State of Michigan. The reporting is based on individuals who present at EDs and may not be representative of the overall population. The coronavirus-like symptoms query searches visit free-text (chief complaint, triage notes, and clinical impression) for fever or …

Bhsc, Bsu, Alma Latina Host: Covid-19 Courageous Conversation, Illinois Mathematics And Science Academy

Brotherhood Sister Circle (BHSC)

Emerging data shows that African Americans and LAtinx communities are being stricken by COVID-19 at a higher rate, and experiencing greater sickness and a higher death toll than other Americans. Some have said that COVID-19 is “ravaging” black communities. In this interactive conversation, four panelists will discuss how racism shapes vulnerability to COVID19, why African Americans are being so heavily impacted, and why these disparities matter.

The Effects Of Therapeutic Back Massage On Psychophysiologic Variables And Immune Function In Spouses Of Cancer Patients, Linda M. Goodfellow-Kruth

Dissertations

Scant attention has been given to help spouses of cancer patients reduce stress associated with their partner's illness. Stress-induced immune function change may be the link between stress and illness. A significant decrease in natural killer cell activity (NKCA) and a high incidence of stress-related disorders, depression, loneliness, and marital disruption have been reported in spouses of cancer patients. Therapeutic back massage (TBM) is an intervention that may be beneficial in reducing stress in spouses of cancer patients. TBM is a systematic form of touch that manipulates soft tissues of the body to promote relaxation. Interventions that induce relaxation have …

2020-May-06-Etsu Offering Summer Online Courses Related To The Covid- Pandemic, University Marketing And Communication, East Tennessee State University

ETSU News

JOHNSON CITY (May 6, 2020) – In response to the COVID-19 pandemic, East Tennessee State University is offering several online summer courses across multiple disciplines that are related to the pandemic and its effects on society.

“The COVID-19 crisis has affected every person and every class at ETSU,” said Dr. Wilsie Bishop, interim provost and senior vice president for academics. “I am proud of the way ETSU has responded to the crisis and how quickly our faculty have adapted courses and used their expertise to create new courses that address subject matter and challenges associated with the pandemic.

“This summer, …

Executive Committee & Cabinet Minutes May 2020, Uno Faculty Senate

Faculty Senate Minutes

These are the official minutes of the Faculty Senate Executive Council Meetings at the University of Nebraska - Omaha (UNO) for Academic year 2019-2020. Minutes are not posted until officially approved by the Executive Council at the following meeting. Minutes are archived yearly within the UNO Library Archives.

Chagas Disease In The New York City Metropolitan Area, Crystal Zheng, Orlando Quintero, Elizabeth K. Revere, Michael B. Oey, Fabiola Espinoza, Yoram A. Puius, Diana Ramirez-Baron, Carlos R. Salama, Luis F. Hidalgo, Fabiana S Machado, Omar Saeed, Jooyoung Shin, Snehal R. Patel, Christina M. Coyle, Herbert B. Tanowitz

Internal Medicine Faculty Publications

Background

Chagas disease, caused by the parasite Trypanosoma cruzi, once considered a disease confined to Mexico, Central America, and South America, is now an emerging global public health problem. An estimated 300 000 immigrants in the United States are chronically infected with T. cruzi. However, awareness of Chagas disease among the medical community in the United States is poor.

Methods

We review our experience managing 60 patients with Chagas disease in hospitals throughout the New York City metropolitan area and describe screening, clinical manifestations, EKG findings, imaging, and treatment.

Results

The most common country of origin of our patients …

Multinational Organizations’ Efforts To Assist Countries Through Covid-19 Crisis, Aidan Lawson, Manuel Leon Hoyos, June Rhee

Documents

No abstract provided.

The Impact Of Multidrug-Resistant Organisms On Outcomes In Patients With Diabetic Foot Infections, Oryan Henig, Jason M. Pogue, Emily Martin, Umar Hayat, Mahmoud Ja'ara, Paul E. Kilgore, Raymond Cha, Sorab Dhar, Keith S. Kaye

Department of Pharmacy Practice

Background. Multidrug-resistant organisms (MDROs) are important diabetic foot infection (DFI) pathogens. This study evaluated the impact of DFIs associated with MDRO pathogens (DFI-MDRO) on clinical outcomes.

Methods. Adults admitted to Detroit Medical Center from January 2012 to December 2015 with culture-positive DFI were included. Associations between outcomes and DFI-MDRO (evaluated as a single group that included methicillin-resistant Staphylococcus aureus [MRSA], vancomycin-resistant enterococci, Enterobacteriaceae resistant to third-generation cephalosporin [3GCR-EC], Acinetobacter baumannii, and Pseudomonas aeruginosa) were analyzed. Outcomes included above- and below-knee lower extremity amputation (LEA), readmissions, and mortality within a year after DFI. A propensity score predicting the likelihood …

Knowledge And Compliance Of Staff In Using The Clostridium Difficile Bundle, Marissa Marie Lovely

DNP and Student Works

Clostridium difficile infection (CDI) is a nosocomial infection that has a significant risk to patient morbidity and mortality. Nurses and patient care technicians (PCTs) provide the most direct care to patients making them at risk of transmitting CDI to patients. It is a collaborative effort of healthcare personnel who provide direct care to patients to prevent transmission of CDI from one patient to another. The objective of this project was to measure staff knowledge about CDI and to evaluate their compliance in using the CDI bundle.

Immunity And Field Efficacy Of Type 2-Containing Polio Vaccines After Cessation Of Trivalent Oral Polio Vaccine: A Population-Based Serological Study In Pakistan, Arie Voorman, Atif Habib, Imtiaz Hussain, Rana Muhammad Safdar, Jamal A. Ahmed, William C. Weldon, Imran Ahmed, Muhammad Umer, Jeffrey Partridge, Sajid Bashir Soofi

Department of Paediatrics and Child Health

Background: In Pakistan and other countries using oral polio vaccine (OPV), immunity to type 2 poliovirus is now maintained by a single dose of inactivated polio vaccine (IPV) in routine immunization, supplemented in outbreak settings by monovalent OPV type 2 (mOPV2) and IPV. While well-studied in clinical trials, population protection against poliovirus type 2 achieved in routine and outbreak settings is generally unknown.
Methods: We conducted two phases of a population-based serological survey of 7940 children aged 6-11 months old, between November 2016 and October 2017 from 13 polio high-risk locations in Pakistan.
Results: Type 2 seroprevalence was 50% among …

The Influence Of Climate Change On Disease And Public Health, Natalie Petruzelli

The Review: A Journal of Undergraduate Student Research

This paper attempts to analyze the growing influence of climate change on the spread and development of diseases, as well as how this continues to affect public health and medical administrations around the world. The prevalence of airborne, waterborne, and vector-borne diseases have been found to be exacerbated as a result of climate change. In addition to this, the paper addresses the reemergence of eliminated diseases and ancient pathogens due to changing temperatures and weather patterns. Finally, the effect of these different conditions on national and international public health organizations and policies is analyzed, including projections on what can be …

Quantification Of Progesterone And 17-Β Estradiol In Mouse Serum By Liquid Chromatography-Tandem Mass Spectrometry, Benjamin Kennard, Allison Cobble, Amy Gravitte, Kaleigh Galloway, Jen Kintner, Jennifer Hall, Stacy C. Brown

Appalachian Student Research Forum

Quantification of progesterone and 17-β estradiol in mouse serum by liquid chromatography-tandem mass spectrometry

Authors:

Benjamin Kennard, Allison Cobble, Amy Gravitte, Keleigh Galloway, Jen Kintner, Jennifer Hall, Stacy Brown

Introduction: In the United States, Chlamydia trachomatis is a commonly appearing sexually transmitted infection¹. It affects the U.S. healthcare system to a tune of about $500 million dollars annually². In women, it generally appears asymptomatic and can lead to severe secondary complications such as pelvic inflammatory diseases or infertility¹. Female sex hormones, estrogen and progesterone, are being identified to have a role in chlamydial infection. …

Taylor Alum Makes National News In The Fight Against Covid-19, Taylor University

2020 Website News Stories

No abstract provided.

2020-05-05_Michiganoverview_Covidsymptoms, Michigan Department Of Health & Human Services

Michigan COVID-19 Syndromic Surveillance System Data

The Syndromic Surveillance System Data report was obtained from Michigan's COVID-19 dashboard, from under the link "​Coronavirus Symptoms": https://www.michigan.gov/coronavirus. Data was compiled by the Michigan Department of Health and Human Services (MDHHS). The information was updated daily.

Syndromic Surveillance System data is obtained from approximately 183 facilities participating in syndromic surveillance (132 Emergency Departments (ED), 51 Urgent Cares) across the State of Michigan. The reporting is based on individuals who present at EDs and may not be representative of the overall population. The coronavirus-like symptoms query searches visit free-text (chief complaint, triage notes, and clinical impression) for fever or …

Markov Chain Model For The Spread Of An Epidemic, Abigail Eleanor Bernhardt

Departmental Honors & Graduate Capstone Projects

In this project, I analyze a mathematical model for the spread of an epidemic using techniques from statistics, probability, and differential equations to track and test the severity of an epidemic. I focus on chlamydia and use 2018 data from the Centers for Disease Control and Prevention which includes prevalence in all genders and ages within the United States. I manipulated MATLAB code for the analysis. The results are examined to understand the stochastic processes which capture the epidemic model. With this understanding, we can map the disease and raise awareness in the populations that are prone to infection, in …