Digital Commons Network^™

Competency Based State Civil Apparatus Structuring In The Framework Of Bureaucracy Reform, Luthfiyah Rosyida, Abdul Hakim, Choirul Saleh

BISNIS & BIROKRASI: Jurnal Ilmu Administrasi dan Organisasi

The direction of bureaucratic reform currently rests on the application of professional state civil apparatus (ASN) management, one of which is through competency based ASN structuring. Appropriate ASN structuring based on competence (the right man in the right place) will bring a positive impact on organizational performance. However, the mismatch between employee competencies and position and placement is still a major problem for ASN. The policies related to existing employee structuring are less effective, so it is necessary to formulate a more adaptive ASN structuring policy that animates Law Number 5 of 2014 concerning ASN, and a competency based ASN …

Histone Demethylase Phf8 Drives Neuroendocrine Prostate Cancer Progression By Epigenetically Upregulating Foxa2., Qiuli Liu, Jian Pang, Lin-Ang Wang, Zhuowei Huang, Jing Xu, Xingxia Yang, Qiubo Xie, Yiqiang Huang, Tang Tang, Dali Tong, Gaolei Liu, Luofu Wang, Dianzheng Zhang, Qiang Ma, Hualiang Xiao, Weihua Lan, Jun Qin, Jun Jiang

PCOM Scholarly Works

Neuroendocrine prostate cancer (NEPC) is a more aggressive subtype of castration-resistant prostate cancer (CRPC). Although it is well established that PHF8 can enhance prostate cancer cell proliferation, whether PHF8 is involved in prostate cancer initiation and progression is relatively unclear. By comparing the transgenic adenocarcinoma of the mouse prostate (TRAMP) mice with or without Phf8 knockout, we systemically examined the role of PHF8 in prostate cancer development. We found that PHF8 plays a minimum role in initiation and progression of adenocarcinoma. However, PHF8 is essential for NEPC because not only is PHF8 highly expressed in NEPC but also animals without …

Recent Advancements In The Removal Of Cyanotoxins From Water Using Conventional And Modified Adsorbents—A Contemporary Review, Tauqeer Abbas, George William Kajjumba, Meena Ejjada, Sayeda Ummeh Masrura, Erica J. Marti, Eakalak Khan, Tammy L. Jones-Lepp

Civil and Environmental Engineering and Construction Faculty Research

The prevalence of cyanobacteria is increasing in freshwaters due to climate change, eutrophication, and their ability to adapt and thrive in changing environmental conditions. In response to various environmental pressures, they produce toxins known as cyanotoxins, which impair water quality significantly. Prolonged human exposure to cyanotoxins, such as microcystins, cylindrospermopsin, saxitoxins, and anatoxin through drinking water can cause severe health effects. Conventional water treatment processes are not effective in removing these cyanotoxins in water and advanced water treatment processes are often used instead. Among the advanced water treatment methods, adsorption is advantageous compared to other methods because of its affordability …

Transcriptional Frontloading Contributes To Cross‐Tolerance Between Stressors, Michael Collins, Melody S. Clark, John I. Spicer, Manuela Truebano

School of Biological and Marine Sciences

No abstract provided.

2019 Symposium On Education In Entertainment And Engineering, Mary K. Pillotte, Rich Dionne

Symposium on Education in Entertainment and Engineering

No abstract provided.

Detaining The Uncooperative Migrant, Siena Anstis, Molly Joeck

Journal of Law and Social Policy

A migrant held in a Canadian prison refuses to hand over a DNA sample to the Canadian Border Services Agency (CBSA). Another refuses to sign a statutory declaration of voluntary return to Somalia where his return is anything but voluntary. Others outright refuse at times to assist in any manner whatsoever with their own deportation. Canadian officials, judges, and adjudicators have treated all of these situations as instances of “non-cooperative” behaviour by an immigration detainee and, in turn, relied on such conduct to impose lengthy and indefinite periods of immigration detention. While the issue of an immigration detainee’s “non-cooperation” seems …

Thinking Broadly: This Volume As A Guide For Abolitionists, Adam Lee

Journal of Law and Social Policy

No abstract provided.

Cvor Model For Assessing The Steppe Ecosystem Health--A Case Study On The Typical Steppe In Inner Mongolia, China, Lixin Wang, Huamin Liu, Zhongling Liu, Wei Wang, Cunzhu Liang, Jie Yang

IGC Proceedings (1977-2023)

No abstract provided.

Health Claims On Food & Supplements: Fact Or Fiction?, Jamie Baum

Diet, Food, Exercise, and Nutrition (D-FEND)

Learning how to understand health claims on foods and supplements.

Safety And Molecular-Toxicological Implications Of Cannabidiol-Rich Cannabis Extract And Methylsulfonylmethane Co-Administration, Kristy R. Kutanzi, Laura E. Ewing, Charles M. Skinner, Charles M. Quick, Stefanie Kennon-Mcgill, Mitchell R. Mcgill, Larry A. Walker, Mahmoud A. Elsohly, Bill J. Gurley, Igor Koturbash

Faculty and Student Publications

© 2020 by the authors. Cannabidiol (CBD) is a biologically active, non-psychotropic component of Cannabis sativa whose popularity has grown exponentially in recent years. Besides a wealth of potential health benefits, ingestion of CBD poses risks for a number of side effects, of which hepatotoxicity and CBD/herb-drug interactions are of particular concern. Here, we investigated the interaction potential between the cannabidiol-rich cannabis extract (CRCE) and methylsulfonylmethane (MSM), a popular dietary supplement, in the mouse model. For this purpose, 8-week-old male C57BL6/J mice received MSM-containing water (80 mg/100 mL) ad libitum for 17 days. During the last three days of treatment, …

Biological Biomedical Seminar | Mohannad Ghazi Al-Saghir On Oct. 19, Ohio University College Of Arts & Sciences

All Forum Articles

No abstract provided.

A Brain-Infecting Parasite Impacts Host Metabolism Both During Exposure And After Infection Is Established, Lauren E. Nadler, Erik Bengston, Erika J. Eliason, Cameron Hassibi, Siri H. Helland-Riise, Ida B. Johansen, Garfield T. Kwan, Martin Tresguerres, Andrew V. Turner, Kelly L. Weinersmith, Øyvind Øverli, Ryan F. Hechinger

Marine & Environmental Sciences Faculty Articles

1. Metabolic costs associated with parasites should not be limited to established infections. Even during initial exposure to questing and attacking parasites, hosts can enact behavioural and physiological responses that could also incur metabolic costs. However, few studies have measured these costs directly. Hence, little is known about metabolic costs arising from parasite exposure.
2. Furthermore, no one has yet measured whether and how previous infection history modulates metabolic responses to parasite exposure.
3. Here, using the California killifish Fundulus parvipinnis and its brain‐infecting parasite Euhaplorchis californiensis, we quantified how killifish metabolism, behaviour and osmoregulatory phenotype changed upon acute exposure to parasite …

Bridging The State And Society: Rethinking Of Social Response And Disaster Risk Reduction During Uncertainties Future Of Covid-19 In Indonesia, Theresia Octastefani

BISNIS & BIROKRASI: Jurnal Ilmu Administrasi dan Organisasi

This study aimed to examine the social aspects of a disaster, in particular related to disaster risk reduction and social response, and to seek the references in adopting or adapting the best practices from a number of countries that have been able to control the Covid-19 spread. To get a comprehensive result, this study used a qualitative method with the data collected through desk studies sourced from the digitally accessed secondary data in the span of January to May 2020. The results of the study showed that unity of command in preparing a strategy of disaster risk reduction from the …

A Review Of The Financial Value Of Faecal Sludge Reuse In Low-Income Countries., Adrian Mallory, Rochelle Holm, Alison Parker

Faculty and Staff Scholarship

Faecal sludge reuse could promote responsible waste management and alleviate resource shortages. However, for this reuse to be carried out at scale, it needs to be financially viable. This paper reviews the financial values of resource recovery from 112 data points from 43 publications from academic and grey literature. The results found 65% of the existing literature is projected rather than being based on observed data from products in practice, with limited studies providing actual experiences of revenue in practice. Some of the estimates of the potential value were ten times those observed in data from operating businesses. Reasons for …

Program, 31st Annual Tampa Bay International Gay And Lesbian Film Festival, October 2-18, 2020, Friends Of The Festival, Inc.

Tampa Bay International Gay & Lesbian Film Festival (TIGLFF) Collection

Program for the 31st Annual Tampa Bay International Gay and Lesbian Film Festival, held between October 2-18, 2020. Includes committee listing, advertisements, letters of welcome, sponsor information, festival jury, schedule, and film descriptions.

Microglia Prevent Beta-Amyloid Plaque Formation In The Early Stage Of An Alzheimer's Disease Mouse Model With Suppression Of Glymphatic Clearance, Weixi Feng, Yanli Zhang, Ze Wang, Hanrong Xu, Ting Wu, Charles Marshall, Junying Gao, Ming Xiao

Physical Therapy Faculty Publications

BACKGROUND: Soluble beta-amyloid (Aβ) can be cleared from the brain through various mechanisms including enzymatic degradation, glial cell phagocytosis, transport across the blood-brain barrier, and glymphatic clearance. However, the relative contribution of each clearance system and their compensatory effects in delaying the pathological process of Alzheimer's disease (AD) are currently unknown.

METHODS: Fluorescent trace, immunofluorescence, and Western blot analyses were performed to compare glymphatic clearance ability and Aβ accumulation among 3-month-old APP695/PS1-dE9 transgenic (APP/PS1) mice, wild-type mice, aquaporin 4 knock out (AQP4^−/−) mice, and AQP4^−/−/APP/PS1 mice. The consequence of selectively eliminating microglial cells, or downregulating apolipoprotein …

Molecular Characterization, Protein-Protein Interaction Network, And Evolution Of Four Glutathione Peroxidases From Tetrahymena Thermophila, Diana Ferro, Rigers Bakiu, Sandra Pucciarelli, Cristina Miceli, Adriana Vallesi, Paola Irato, Gianfranco Santovito

Manuscripts, Articles, Book Chapters and Other Papers

Glutathione peroxidases (GPxs) form a broad family of antioxidant proteins essential for maintaining redox homeostasis in eukaryotic cells. In this study, we used an integrative approach that combines bioinformatics, molecular biology, and biochemistry to investigate the role of GPxs in reactive oxygen species detoxification in the unicellular eukaryotic model organism Tetrahymena thermophila. Both phylogenetic and mechanistic empirical model analyses provided indications about the evolutionary relationships among the GPXs of Tetrahymena and the orthologous enzymes of phylogenetically related species. In-silico gene characterization and text mining were used to predict the functional relationships between GPxs and other physiologically-relevant processes. The GPx …

Nad Metabolism In Male Reproductive Aging, Mirella L. Meyer-Ficca

Funded Research Records

No abstract provided.

Points Of Pride, Georgia Southern University

Points of Pride (2013-2023)

• Rankings
• Academics
• Athletics
• Facilities
• Outreach
• Research

Ionomic Profiling Of Pericardial Fluid In Ischemic Heart Disease, Noman Khan, Satwat Hashmi, Amna Jabbar Siddiqui, Sabiha Farooq, Shahid Ahmed Sami, Nageeb Basir, Syedah Saira Bokhari, Hasanat Sharif, Sanaullah Junejo, Syed Ghulam Musharraf

Department of Biological & Biomedical Sciences

Metals are essential cofactors that play a crucial role in heart function at the cell and tissue level. Information regarding the role of metals in the pericardial fluid and its ionome in ischemic heart disease (IHD) is limited. We aimed to determine the association of elements in pericardial fluid and serum samples of IHD patients and their correlation with systolic and diastolic function. IHD patients have been studied with systolic and diastolic dysfunction categorized on the basis of echocardiographic parameters. We measured concentrations of sixteen elements in the pericardial fluid and serum of 46 patients obtained during open heart surgery …

The Ames Library Partners To Digitize Medieval Manuscripts, University Communications

News and Events (Discontinued Series)

No abstract provided.

The Virtues Of Being Human: Faith, Hope, And Love In James Gray's The Immigrant (2013), The Lost City Of Z (2016), And Ad Astra (2019), John Adair

Journal of Religion & Film

James Gray’s three most recent features reflect on the Christian virtues of faith, hope, and love, revealed and developed through encounters with others. The Immigrant (2013) reveals the way faith informs familial commitments, social bonds, and a life-giving response to suffering and injustice. The Lost City of Z (2016) portrays a dreamer, a man whose hopeful vision of another world animates every aspect of his being. And Gray’s most recent feature, Ad Astra (2019) traces a man’s turn toward relationship as he discovers what it means to love. In each case, as Gray’s characters display these virtues, the characters transcend …

Consuming Bollywood, Anjali Gera Roy

Journal of Religion & Film

Hindi popular cinema, marked with sartorial, visual and material excess, has paradoxically portrayed acquisition of wealth or unregulated consumption as inimical to the Chaturvarga philosophy, or the idea that an individual should seek four goods – Artha (wealth), Kama (pleasure), Dharma (duty) and Moksha (renunciation) - in moderation in order to lead a balanced life. While its visual imagery is largely oriented towards Artha or pleasure, Dharma, in its meaning as duty, has been the prime motivation of Hindi or Bombay cinema’s characters and structures the cinematic conflict and action. However, Hindi cinema appears to have undergone a phase-shift in …

The Monstrous Other And The Biblical Narrative Of Ruth, Jonathan Lyonhart, Jennifer Matheny

Journal of Religion & Film

Guillermo Del Toro’s The Shape of Water (2017) restages the biblical narrative of Ruth in Cold War America, crystallizing the parallel through setting numerous scenes at a local cinema that is playing The Story of Ruth (1960). The book of Ruth tells the tale of how a non-Israelite outsider could be welcomed into the kingdom of God and ultimately into the lineage of Christ. Likewise, del Toro populates his tale with multiple outsiders—multiple ‘Ruths’—including a mute woman, an African American cleaner, a Russian Communist, and an elderly homosexual male. However, these are merely reflections of the ultimate outsider, Del Toro’s …

Islam, Immigrants, And The Angry Young Man: Laurent Cantet And The “Limits Of Fabricated Realism”, Elizabeth Toohey

Journal of Religion & Film

My paper juxtaposes Laurent Cantet’s films The Class (2008) and The Workshop (2017) to explore how they are infused with concerns about radical Islam and the place of Muslim immigrants in the West. Both films center on "angry young men" facing class-based marginalization, who are prone to anti-social behavior. In The Workshop, however, a great effort is made to reveal the intellectual potential and moral complexity of the young white French-born Antoine, whose alienation is defined by his attraction to the xenophobic and Islamophobic rhetoric of the Far Right, whereas viewers of The Class are kept at arm’s length …

Effect Of Captopril On Paracetamol Induced Nephrotoxicity In Rats: Histological Study, Turki Alsheika

Al Jinan الجنان

Paracetamol is widely used without prescription as an over the counter (OTC) drug. Many studies reported that it causes renal toxicity unlike ACE inhibitors like Captopril that can have renal protective effects. Since many patients may take Paracetamol and Captopril concomitantly, the aim of this study is to evaluate the renal protective effect of Captopril on Paracetamol induced nephrotoxicity. The present study was conducted in two phases. Phase (1): high dose Paracetamol: Animals were divided into 4 groups of 6 rats each. Group 1 (control group), Group 2 (Paracetamol 3000 mg/kg group) and Group 3 (Captopril 20 mg/kg group) were …

Diversity And Ethnobotany Of Fodder Plants In The Himalayan Rangelands: A Case Of The Uttarakhand Mountains, India, Vir Singh, R. D. Gaur

IGC Proceedings (1977-2023)

No abstract provided.

A Resource‐Explicit Population Model For The Management Of A Dominant Shrub That Takes Into Account The Ruminants' Feeding Strategy, D. Magda, Cyril Agreil, E. Chambon-Dubreuil, M. Jarry, Michel Meuret

IGC Proceedings (1977-2023)

No abstract provided.

Study On Some Models Exploiting Pasture Industry In The South Of China, Keyun Li, Xiong Li

IGC Proceedings (1977-2023)

No abstract provided.

Sexual Dimorphism In The Meiotic Requirement For Prdm9: A Mammalian Evolutionary Safeguard., Natalie Powers, Beth L Dumont, Chihiro Emori, Raman Akinyanju Lawal, Catherine Brunton, Kenneth Paigen, Mary Ann Handel, Ewelina Bolcun-Filas, Petko M. Petkov, Tanmoy Bhattacharyya

Faculty Research 2020

In many mammals, genomic sites for recombination are determined by the histone methyltransferase PRMD9. Some mouse strains lacking PRDM9 are infertile, but instances of fertility or semifertility in the absence of PRDM9 have been reported in mice, canines, and a human female. Such findings raise the question of how the loss of PRDM9 is circumvented to maintain fertility. We show that genetic background and sex-specific modifiers can obviate the requirement for PRDM9 in mice. Specifically, the meiotic DNA damage checkpoint protein CHK2 acts as a modifier allowing female-specific fertility in the absence of PRDM9. We also report that, in the …