Digital Commons Network^™

Killing Wotus 2015: Why Three Rulemakings May Not Be Enough, Stephen M. Johnson

Articles

This Article will discuss the procedural and substantive flaws in the three rulemaking efforts by the agencies. One or more of the rules (or the 2015 rule) will likely be litigated for the next several years and, ultimately, it is likely that the question of the scope of the federal government’s jurisdiction over “waters of the United States” will return to the Supreme Court. However, since challenges to those rules must originate in Federal district courts, it could take some time before the question returns to the Court.

Part II of this Article discusses the 2015 rule, including the motivation …

The Chumash Heritage National Marine Sanctuary: An Exploration Of Changing The Discourse On Conservation, Arielle Ben-Hur

Pitzer Senior Theses

In 2015, the Northern Chumash Tribal Council submitted a National Marine Sanctuary Nomination to establish the Chumash Heritage National Marine Sanctuary– a means by which to ensure the protection of one of the most culturally and biologically diverse coastlines in the world. On October 5, 2015, John Armor of the National Oceanic and Atmospheric Administration (NOAA) responded to the nomination, adding it to the inventory of areas NOAA may consider in the future for national marine sanctuary designation.

In my thesis, I explore how the nomination of the Chumash Heritage National Marine Sanctuary acts as a platform from which Traditional …

Characterizing Changes In The Colonic Epithelium Of Lrig3 Null Mice, Natalie Pedicino

Scripps Senior Theses

The lining of the colon, or colonic epithelium, is a very dynamic and highly regulated tissue in the human body. Colonic stem cells are a key component of this tissue, and they make up the stem cell niche, which is found at the base of the colonic crypt. Regeneration of the colonic epithelium, which occurs on a weekly basis, is a complex process, and proteins responsible for directing regeneration are still being discovered. Two critical regulatory proteins, Lrig1 and Lrig3, have been shown to modulate the EGFR pathway, a key signaling pathway for growth, differentiation, and regeneration. Data from the …

Teaching Texting On A Smart Phone To Children And Adolescents With Autism Spectrum Disorder (Asd), Jenna Gilder

CGU Theses & Dissertations

Children and adolescents diagnosed with autism spectrum disorder (ASD) have deficits in social communication ( Diagnostic and Statistical Manual of Mental Disorders -5th edition, APA, 2013). These deficits are significantly pronounced when individuals with ASD attempt to engage in conversations. Due to advances in technology, children and adolescents are now conversing through computer mediated communication (CMC; Pew, 2015, 2018). Texting in particular is one popular form of CMC that may mitigate the non-verbal social skill deficits seen in individuals with ASD, such as eye contact and tone of voice. Despite the potential of texting and its' popularity as a CMC …

Methods For Broad-Scale Plant Phenology Assessments Using Citizen Scientists’ Photographs, Vijay V. Barve, Laura Brenskelle, Daijiang Li, Brian J. Stucky, Narayani V. Barve, Maggie M. Hantak, Bryan S. Mclean, Daniel J. Paluh, Jessica A. Oswald, Michael W. Belitz, Ryan A. Folk, Robert P. Guralnick

Faculty Publications

© 2020 Barve et al. Applications in Plant Sciences is published by Wiley Periodicals, Inc. on behalf of the Botanical Society of America Premise: Citizen science platforms for sharing photographed digital vouchers, such as iNaturalist, are a promising source of phenology data, but methods and best practices for use have not been developed. Here we introduce methods using Yucca flowering phenology as a case study, because drivers of Yucca phenology are not well understood despite the need to synchronize flowering with obligate pollinators. There is also evidence of recent anomalous winter flowering events, but with unknown spatiotemporal extents. Methods: We …

Impaired Purine Homeostasis Plays A Primary Role In Trimethoprim-Mediated Induction Of Virulence Genes In Burkholderia Thailandensis, Sudarshan S. Thapa, Anne Grove

Faculty Publications

© 2020 John Wiley & Sons Ltd One of the most commonly prescribed antibiotics against Burkholderia infections is co-trimoxazole, a cocktail of trimethoprim and sulfamethoxazole. Trimethoprim elicits an upregulation of the mal gene cluster, which encodes proteins involved in synthesis of the cytotoxic polyketide malleilactone; trimethoprim does so by increasing expression of the malR gene, which encodes the activator MalR. We report that B. thailandensis grown on trimethoprim exhibited increased virulence against Caenorhabditis elegans. This enhanced virulence correlated with an increase in expression of the mal gene cluster. Notably, inhibition of xanthine dehydrogenase by addition of allopurinol led to similar …

Modeling The Effects Of Trait-Mediated Dispersal On Coexistence Of Mutualists, James T. Cronin, Jerome Goddard, Amila Muthunayake, Ratnasingham Shivaji

Faculty Publications

© 2020 the Author(s), licensee AIMS Press. This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0) Even though mutualistic interactions are ubiquitous in nature, we are still far from making good predictions about the fate of mutualistic communities under threats such as habitat fragmentation and climate change. Fragmentation often causes declines in abundance of a species due to increased susceptibility to edge effects between remnant habitat patches and lower quality “matrix” surrounding these focal patches. It has been argued that ecological communities are replete with trait-mediated indirect effects, and that these effects …

Modeling The Effects Of Density Dependent Emigration, Weak Allee Effects, And Matrix Hostility On Patch-Level Population Persistence, James T. Cronin, Nalin Fonseka, Jerome Goddard, Jackson Leonard, Ratnasingham Shivaji

Faculty Publications

© 2020 the Author(s), licensee AIMS Press. This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0) The relationship between conspecific density and the probability of emigrating from a patch can play an essential role in determining the population-dynamic consequences of an Allee effect. In this paper, we model a population that inside a patch is diffusing and growing according to a weak Allee effect per-capita growth rate, but the emigration probability is dependent on conspecific density. The habitat patch is one-dimensional and is surrounded by a tuneable hostile matrix. We consider five …

Taxonomic Resolution Affects Host-Parasite Association Model Performance, Tad A. Dallas, Daniel J. Becker

Faculty Publications

© 2020 Georg Thieme Verlag. All rights reserved. Identifying the factors that structure host-parasite interactions is fundamental to understand the drivers of species distributions and to predict novel cross-species transmission events. More phylogenetically related host species tend to have more similar parasite associations, but parasite specificity may vary as a function of transmission mode, parasite taxonomy, or life history. Accordingly, analyses that attempt to infer host-parasite associations using combined data on different parasite groups may perform quite differently relative to analyses on each parasite subset. In essence, are more data always better when predicting host-parasite associations, or does parasite taxonomic …

Behavioral, Morphological, And Ecological Trait Evolution In Two Clades Of New World Sparrows (Aimophila And Peucaea, Passerellidae), Carla Cicero, Nicholas A. Mason, Lauryn Benedict, James D. Rising

Faculty Publications

Copyright 2020 Cicero et al. The New World sparrows (Passerellidae) are a large, diverse group of songbirds that vary in morphology, behavior, and ecology. Thus, they are excellent for studying trait evolution in a phylogenetic framework. We examined lability versus conservatism in morphological and behavioral traits in two related clades of sparrows (Aimophila, Peucaea), and assessed whether habitat has played an important role in trait evolution. We first inferred a multi-locus phylogeny which we used to reconstruct ancestral states, and then quantified phylogenetic signal among morphological and behavioral traits in these clades and in New World sparrows more broadly. Behavioral …

Improving Natural Product Research Translation: From Source To Clinical Trial, Barbara C. Sorkin, Adam J. Kuszak, Gregory Bloss, Naomi K. Fukagawa, Freddie Ann Hoffman, Mahtab Jafari, Bruce Barrett, Paula N. Brown, Frederic D. Bushman, Steven J. Casper, Floyd H. Chilton, Christopher S. Coffey, Mario G. Ferruzzi, D. Craig Hopp, Mairead Kiely, Daniel Lakens, John B. Macmillan, David O. Meltzer, Marco Pahor, Jeffrey Paul, Kathleen Pritchett-Corning, Sara K. Quinney, Barbara Rehermann, Kenneth D.R. Setchell, Nisha S. Sipes, Jacqueline M. Stephens, D. Lansing Taylor, Hervé Tiriac, Michael A. Walters, Dan Xi, Giovanna Zappalá, Guido F. Pauli

Faculty Publications

© 2019 Federation of American Societies for Experimental Biology While great interest in health effects of natural product (NP) including dietary supplements and foods persists, promising preclinical NP research is not consistently translating into actionable clinical trial (CT) outcomes. Generally considered the gold standard for assessing safety and efficacy, CTs, especially phase III CTs, are costly and require rigorous planning to optimize the value of the information obtained. More effective bridging from NP research to CT was the goal of a September, 2018 transdisciplinary workshop. Participants emphasized that replicability and likelihood of successful translation depend on rigor in experimental design, …

Novel Resistant Starch Type 4 Products Of Different Starch Origins, Production Methods, And Amounts Are Not Equally Fermented When Fed To Sprague-Dawley Rats, Diana B. Coulon, Ryan Page, Anne M. Raggio, Justin Guice, Brain Marx, Vishnupriya Gourineni, Maria L. Stewart, Michael J. Keenan

Faculty Publications

© 2019 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim Scope: The possible mechanisms of production of four novel resistant starch type 4 (RS4) products for total cecal fermentation in an in vivo rodent model are evaluated. Methods and results: Forty weanling rats are randomly assigned to five groups (n = 8) for a 3-week study. Starches are the RS type 4 products, as 10% of weight of RS diets (RSA–RSD), and AMIOCA starch (100% amylopectin) comprises 53.6% weight of control (CON) and 43.6% weight of RS diets. The RS products vary by percent purity and origin (potato, corn, tapioca). At …

The Landscape Of Accessible Chromatin In Bovine Oocytes And Early Embryos, Hao Ming, Jiangwen Sun, Rolando Pasquariello, Lauren Gatenby, Jason Herrick, Ye Yuan, Carlos Pinto, Kenneth R. Bondioli, Rebecca L. Krisher, Zongliang Jiang

Faculty Publications

© 2020, © 2020 Informa UK Limited, trading as Taylor & Francis Group. Chromatin reorganization governs the regulation of gene expression during preimplantation development. However, the landscape of chromatin dynamics in this period has not been explored in bovine. In this study, we constructed a genome-wide map of accessible chromatin in bovine oocytes and early embryos using an improved assay for transposase-accessible chromatin with high-throughput sequencing (ATAC-seq) which revealed unique features of the accessible chromatin during bovine early embryo development. We found that chromatin accessibility is low in oocytes and 2-/4-cell embryos, followed by a significant increase in embryos during …

Novel Resistant Starch Type 4 Products Of Different Starch Origins, Production Methods, And Amounts Are Not Equally Fermented When Fed To Sprague-Dawley Rats, Diana B. Coulon, Ryan Page, Anne M. Raggio, Justin Guice, Brain Marx, Vishnupriya Gourineni, Maria L. Stewart, Michael J. Keenan

Faculty Publications

© 2019 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim Scope: The possible mechanisms of production of four novel resistant starch type 4 (RS4) products for total cecal fermentation in an in vivo rodent model are evaluated. Methods and results: Forty weanling rats are randomly assigned to five groups (n = 8) for a 3-week study. Starches are the RS type 4 products, as 10% of weight of RS diets (RSA–RSD), and AMIOCA starch (100% amylopectin) comprises 53.6% weight of control (CON) and 43.6% weight of RS diets. The RS products vary by percent purity and origin (potato, corn, tapioca). At …

The Landscape Of Accessible Chromatin In Bovine Oocytes And Early Embryos, Hao Ming, Jiangwen Sun, Rolando Pasquariello, Lauren Gatenby, Jason Herrick, Ye Yuan, Carlos Pinto, Kenneth R. Bondioli, Rebecca L. Krisher, Zongliang Jiang

Faculty Publications

© 2020, © 2020 Informa UK Limited, trading as Taylor & Francis Group. Chromatin reorganization governs the regulation of gene expression during preimplantation development. However, the landscape of chromatin dynamics in this period has not been explored in bovine. In this study, we constructed a genome-wide map of accessible chromatin in bovine oocytes and early embryos using an improved assay for transposase-accessible chromatin with high-throughput sequencing (ATAC-seq) which revealed unique features of the accessible chromatin during bovine early embryo development. We found that chromatin accessibility is low in oocytes and 2-/4-cell embryos, followed by a significant increase in embryos during …

Charros: How Mexican Cowboys Are Remapping Race And American Identity, Andrew Sluyter

Faculty Publications

No abstract provided.

Living By Inches: The Smells, Sounds, Tastes, And Feeling Of Captivity In Civil War Prisons, Holly A. Pinheiro Jr.

Civil War Book Review

Contrary to popular opinion, Civil War battles were not always formal military engagements or guerilla skirmishes between Confederate and U.S. forces. Hundreds of thousands of prisoners of war (POWs) knew that their battles were starkly different from armed conflicts. POWs understood that fights in captivity occurred against their enemies, themselves, elements, animals, insects, and diseases. We know an extensive amount of information about infamous prison camps, including Andersonville and Elmira. Recent scholarship has brought to light the complexity of pardoning and surrendering processes and the "black flag" policy's racial politics. However, the day-to-day lived experiences of imprisoned soldiers and their …

Informe Tecnico De Los Trabajos De Campo Del Proyecto De Investigación Arqueológica Cerro San Isidro, Valle De Nepeña, Costa De Ancash -- Temporada 2019, David Chicoine, Jeisen Navarro

Faculty Publications

No abstract provided.

Phlebotomines (Diptera: Psychodidae) From A Urban Park Of Belém, Pará State, Northern Brazil And Potential Implications In The Transmission Of American Cutaneous Leishmaniasis, Yetsenia D.V. Sánchez Uzcátegui, Thiago Vasconcelos Dos Santos, Fernando T. Silveira, Patricia K.S. Ramos, Eduardo José M. Dos Santos, Marinete M. Póvoa, Lane Foil

Faculty Publications

© 2019 The Author(s) 2019. Published by Oxford University Press on behalf of Entomological Society of America. In urban ecotourism parks, the life cycle of American cutaneous leishmaniasis (ACL) agents can remain established, where phlebotomines may comprise potential risks for visitors. The present study aimed to survey the phlebotomine fauna of a forest park 'Bosque Rodriques Alves-Jardim Botânico da Amazônia' (BRAJBA), in the urban area of Belém, Brazil. The park was monthly surveyed in 2018 using CDC light traps placed in ground and canopy strata. Leishmania spp. isolated from dissected females were characterized by polymerase chain reaction-restriction fragment length polymorphism …

Tropism, Pathology, And Transmission Of Equine Parvovirus-Hepatitis, Joy Ellen Tomlinson, Mason Jager, Alyssa Struzyna, Melissa Laverack, Lisa Ann Fortier, Edward Dubovi, Lane D. Foil, Peter D. Burbelo, Thomas J. Divers, Gerlinde R. Van De Walle

Faculty Publications

© 2020, © 2020 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group, on behalf of Shanghai Shangyixun Cultural Communication Co., Ltd. Equine parvovirus-hepatitis (EqPV-H) has recently been associated with cases of Theiler's disease, a form of fulminant hepatic necrosis in horses. To assess whether EqPV-H is the cause of Theiler's disease, we first demonstrated hepatotropism by PCR on tissues from acutely infected horses. We then experimentally inoculated horses with EqPV-H and 8 of 10 horses developed hepatitis. One horse showed clinical signs of liver failure. The onset of hepatitis was temporally associated with seroconversion and …

Hepatic Ikkε Expression Is Dispensable For High-Fat Feeding-Induced Increases In Liver Lipid Content And Alterations In Glucose Tolerance, J. Jason Collier, Heidi M. Batdorf, Tamra M. Mendoza, David H. Burk, Thomas M. Martin, Jingying Zhang, Randall L. Mynatt, Susan J. Burke

Faculty Publications

© 2020 the American Physiological Society. There are endocrine and immunological changes that occur during onset and progression of the overweight and obese states. The inhibitor of nuclear factor-κB kinase-ε (IKKε) was originally described as an inducible protein kinase; whole body gene deletion or systemic pharmaceutical targeting of this kinase improved insulin sensitivity and glucose tolerance in mice. To investigate the primary sites of action associated with IKKε during weight gain, we describe the first mouse line with conditional elimination of IKKε in the liver (IKKεAlb-/-). IKKεAlb-/- mice and littermate controls gain weight, show similar changes in body composition, and …

Response Of Liver Metabolic Pathways To Ketogenic Diet And Exercise Are Not Additive, Tai Yu Huang, Felicia R. Goldsmith, Scott E. Fuller, Jacob Simon, Heidi M. Batdorf, Matthew C. Scott, Nabil M. Essajee, John M. Brown, David H. Burk, Christopher D. Morrison, Susan J. Burke, J. Jason Collier, Robert C. Noland

Faculty Publications

© Lippincott Williams & Wilkins. Purpose Studies suggest ketogenic diets (KD) produce favorable outcomes (health and exercise performance); however, most rodent studies have used a low-protein KD, which does not reflect the normal- to high-protein KD used by humans. Liver has an important role in ketoadaptation due to its involvement in gluconeogenesis and ketogenesis. This study was designed to test the hypothesis that exercise training (ExTr) while consuming a normal-protein KD (NPKD) would induce additive/synergistic responses in liver metabolic pathways. Methods Lean, healthy male C57BL/6J mice were fed a low-fat control diet (15.9% kcal protein, 11.9% kcal fat, 72.2% kcal …

Where Virtue Goes: Stories, Radhika Vu Thanh Vy

Honors Theses

This story is a parallel narrative featuring the life in a fictional remote village in Vietnam some time during the 1800s, as well as the present-day life of a Vietnamese immigrant family in the US. The first narrative explores the efforts of a feminist duo, a matchmaker and a midwife, to help a young pregnant woman get out of an unhappy marriage. In doing so, the duo attempt to unravel traditional gender roles and oppressive social customs, and reweave the village social fabric. The other narrative explores a present-day marriage, one that is as much a disintegrating relationship as one …

Regarding Narrative Justice, Womxn, Geeta Tewari

Michigan Journal of Race and Law

The story within this article explores how narrative justice can be applied as a form of advocacy for persons seeking access to justice. The questions—what is narrative justice? How do we define it?—deserve a separate space, which will be shared in a forthcoming article. Meanwhile, in short, narrative justice is the power of the word—written, spoken, articulated with the emotion or experience of an individual or collective, to shape or express reaction to law and policy.

Survey On Needs Of People Living Unsheltered, Marisa Zapata, Homelessness Research & Action Collaborative, Joint Office Of Homeless Services, Shannon Singleton, Street Roots

Homelessness Research & Action Collaborative Publications and Presentations

Portland State University’s Homelessness Research & Action Collaborative worked with the Joint Office of Homeless Services, Shannon Singleton, and Street Roots to survey people who are living unsheltered to better understand their needs. Because of the racial disparities that we know exist, we set out to create and administrate a survey that would also ask these questions with a focus on people of color.

In all, 383 people took the rapidly deployed and quickly crafted survey over the course of two weeks. Nearly 40% of those surveyed identified as people of color with the highest representation among Black people and …

Columbus State University Honors College: Senior Theses, Fall 2020/Spring 2021, Abigail Abernathy, Micah Arnholt, Joshua Butler, Ashlyn Dewberry, Vivian Duncan, Shannon Eshman, Macy Frazier, Bailey Gaines, Meenal Joshi, Brenna Kincaid, Taylor Lewis, Molli Mcginnis, Elijah Neundorfer, Erin Perry, Grace Pippas, Elise Rhinebolt, Caitlin Schwartz, Tatseyana Taylor, Lyndi Whetzel

Senior Theses from the Honors College

This is a collection of senior theses written by honors students at Columbus State University during the Fall 2020 and Spring 2021 semesters.

Titles:

- "Comparison of Histological Techniques to Determine Intersex Prevalence and Severity in Testes of Largemouth Bass *Micropterus salmoides) and Spotted Bass (Micropterus punctulatus) From the Chattahoochee River, U.S.A" , by Abigail Abernathy

- "The Applications of Space Syntax Theory and Depthmap Technology to Problems of Race and Income Inequality in Midtown, Columbus ,GA" , by Micah Arnholt

- "Utilizing the Dalcroze Method in the Secondary Choral Classroom" , by Joshua Butler

- "A Tale of Two …

Projecting Regions Of North Atlantic Right Whale, Eubalaena Glacialis, Habitat Suitability In The Gulf Of Maine In 2050, Camille Ross

Honors Theses

North Atlantic right whales (Eubalaena glacialis) are endangered. Understanding the role environmental conditions play in habitat suitability is key to determining the regions in need of protection for conservation of the species, particularly as climate change shifts suitable habitat. This thesis uses three species distribution modeling algorithms, together with historical data on whale abundance(1993 to 2009) and environmental covariates to build monthly ensemble models of past E. glacialis habitat suitability in the Gulf of Maine. Then, the models are projected onto the year 2050 for a range of climate scenarios. Specifically, the distribution of the species was modeled …

The “Humanitarian Mystique:” Tracing The Rhetoric And Politics Of Aid In Southeast Asia From The Age Of The Civilizing Mission To The Present, Elizabeth M. Holland

Honors Theses

In contemporary Western popular culture, humanitarian action often serves as the ultimate expression of altruism, compassion, and moral obligation. This research historicizes humanitarianism to understand the assumptions that underlie its affective appeal. Oversimplified narratives of aid work frequently fail to acknowledge the historical and geopolitical context in which this work occurs. I argue that humanitarianism, as both a discursive tool and code of practice, makes visible some legacies of the ‘civilizing mission’ – the ideology used to justify colonialism in the late nineteenth and early twentieth centuries. An exercise in comparative history, this research consists of three spatially and temporally …

Propaganda Y Progreso: El Rol Paradójico De La Magia En La España Premoderna, Alexander K. Rhodes

Honors Theses

La magia tiene varios roles diferentes en la literatura española premoderna. A causa de las connotaciones pecaminosas de la magia, frecuentemente se usa para discriminar contra un grupo subalterno, como en la obra de teatro El niño inocente de La Guardia de Lope de Vega. Se ve que esta forma de discriminación difunde y apoya la anxiety of sameness definida por Christina Lee. La anxiety of sameness es el temor de los nobles de ser infiltrados por los no nobles, incluyendo a los judíos, los moriscos y los de la clase baja. Pero, como se ve en esta tesis, la …

Development And Validation Of Gene Delivery Methods For ​Crassostrea Virginica, Adrienne N. Tracy

Honors Theses

The Eastern oyster (Crassostrea virginica) is an important part of the East Coastal USA economy because aquaculture creates jobs. Sadly, the oysters are under constant threat due to increasing pollution, red tides, and diseases. Bivalves, and oysters in particular, are also becoming potential model organisms in medical research. With the sequencing of the oyster genome, scientists are focusing on deciphering the function of the predicted genes. However, the limited number of molecular and cellular tools available makes functional annotation of the genome challenging. A consistent, replicable gene delivery system needs to be developed to assess gene function and understand the …