Digital Commons Network^™

New Ohio Study Shows Huge Dinosaurs Evolved Different Cooling Systems To Combat Heat Stroke (October 16, 2019), University Communications And Marketing

OHIO News Articles Archive

No abstract provided.

Sustainable Infrastructure Hub Seminar Led By Dr. David Bayless Is Nov. 6 (October 16, 2019), University Communications And Marketing

OHIO News Articles Archive

No abstract provided.

Short Term Effects Of Hurricane Irma And Cyanobacterial Blooms On Ammonium Cycling Along A Freshwater-Estuarine Continuum In South Florida, Justyna J. Hampel, Mark J. Mccarthy, Megan H. Reed, Silvia E. Newell

Faculty Publications

Lacustrine and coastal systems are vulnerable to the increasing number and intensity of tropical storms driven by climate change. Strong winds associated with tropical storms can mobilize nutrients in sediments and alter nitrogen and phosphorus cycling, leading to amplification of preexisting conditions, such as eutrophication and cyanobacterial blooms (cyanoHABs). In 2016, Florida declared a State of Emergency within and downstream of Lake Okeechobee (LO) due to toxic cyanobacterial blooms (primarily Microcystis). The blooms originated in LO, but flood control measures released water from LO to the brackish St. Lucie Estuary (SLE). In September 2017, Hurricane Irma traversed the Florida …

Communication About Influenza Prevention: A Case Study Of Arkansas State University Students Health Center, Oyeronke Oyindamola Afolabi

Student Theses and Dissertations

The purpose of this case-study was to examine what and how the Arkansas State University Student Health Center (ASUSHC) communicates about influenza and influenza vaccination. To this end, the researcher conducted thematic analysis of social media posts and flyers disseminated by the ASUSCH on influenza and influenza vaccinations. ASUSHC provides an array of medical services including treatment of minor illnesses and injuries, physical exams, and immunizations. I adopted a reflective memoing in conducting a thematic analysis as recommended by Ryan and Branerd (2003). There were two research questions posed and four themes emerged from the first research question which are: …

Redefining Noradrenergic Neuromodulation Of Behavior: Impacts Of A Modular Locus Coeruleus Architecture, Dan J. Chandler, Patricia Jensen, Jordan G. Mccall, Anthony E. Pickering, Lindsay A. Schwarz, Nelson K. Totah

Open Access Publications

The locus coeruleus (LC) is a seemingly singular and compact neuromodulatory nucleus that is a prominent component of disparate theories of brain function due to its broad noradrenergic projections throughout the CNS. As a diffuse neuromodulatory system, noradrenaline affects learning and decision making, control of sleep and wakefulness, sensory salience including pain, and the physiology of correlated forebrain activity (ensembles and networks) and brain hemodynamic responses. However, our understanding of the LC is undergoing a dramatic shift due to the application of state-of-the-art methods that reveal a nucleus of many modules that provide targeted neuromodulation. Here, we review the evidence …

Adjuvant Chemotherapy And Survival Among Patients 70 Years Of Age And Younger With Node-Negative Breast Cancer And The 21-Gene Recurrence Score Of 26-30, Seho Park, Yunan Han, Ying Liu, Adetunji T Toriola, Lindsay L Peterson, Graham A Colditz, Seung Il Kim, Young Up Cho, Byeong-Woo Park, Yikyung Park

Open Access Publications

BACKGROUND: The benefits of chemotherapy in node-negative, hormone receptor-positive, and human epidermal growth factor receptor 2 (HER2)-negative breast cancer patients with the 21-gene recurrence score (RS) of 18-30, particularly those with RS 26-30, are not known.

METHODS: Using the Surveillance, Epidemiology, and End Results (SEER) data, we retrospectively identified 29,137 breast cancer patients with the 21-gene RS of 18-30 diagnosed between 2004 and 2015. Mortality risks according to the RS and chemotherapy use were compared by the Kaplan-Meier method and Cox's proportional hazards model.

RESULTS: Among the breast cancer patients with the RS 18-30, 21% of them had RS 26-30. …

The Combined Effect Of Heat And Corona Charge On Molecular Delivery To A T-Cell Line In-Vitro, Molly A. Skinner

USF Tampa Graduate Theses and Dissertations

Gene therapy and immunotherapy are new up and coming fields in cancer treatment. In August of 2017, the first gene therapy was FDA approved called CAR-T cell therapy("FDA approval brings first gene therapy to the United States," 2017). This therapy uses the patient’s

own T-cells that are genetically modified to attack the cancerous cells. Currently, it takes 4-6 weeks to genetically modify these T-cells, which can be the difference between life and death for a cancer patient (Cheng, Jun, Jiang, & Xi, 2017). There is evidence that gene electrotransfer can help expedite the genetic modification process by having an easy …

Multi-Year Water Quality Data Reveal Highly Variable Timing And Magnitude Of Metabolism And Physicochemical Drivers In An Aridland River Network, Betsy Marie Summers

Civil Engineering ETDs

Streams and rivers process and transport carbon to downstream systems and are important components of global and regional carbon budgets. Ecosystem functions, including gross primary production (GPP) and ecosystem respiration (ER), can be used to improve understanding of carbon cycling and ecosystem health in lotic systems. Whole-stream metabolism (GPP and ER) has been studied extensively in headwater streams. However, we know less about the variability in GPP and ER in aridland rivers and tributary streams despite being globally abundant and vulnerable systems to changing climate. This dissertation explores temporal and spatial variation of GPP and ER in a montane stream …

Effect Of Student Teams-Achievement Divisions And Think–Pair–Share On Students’ Interest In Reading Comprehension, Eucharia Okwudilichukwu Ugwu

Journal of Educational Research and Practice

The study investigated the effect of two cooperative learning strategies (the student teams-achievement divisions and think–pair–share methods) on students’ interest in reading comprehension. Seventy-eight senior secondary II students were randomly selected from three schools in Vandeikya Local Government Area, Benue State, Nigeria. A pretest–posttest quasi-experimental design was adopted. The Interest in Reading Inventory (R = 0.09) was the instrument used. Two hypotheses were tested at .05 levels of significance. Three intact classes were randomly assigned as Experimental Group 1, Experimental Group 2, and the control group. The data collected were analyzed using mean and standard deviation, and analysis of …

Facilitating The Creative Process Through Collaboration, Jennifer K. Fortuna

The Open Journal of Occupational Therapy

Miles Parker Scharfenberg, an artist based in Richland, Michigan, provided the cover art for the Fall 2019 edition of The Open Journal of Occupational Therapy (OJOT). “Late Night Fireworks” is a 30” x 40” painting made from acrylic on canvas. Born 15 weeks premature, Miles’ multiple health impairments have made it difficult to engage in meaningful occupations, such as painting. With support from his mother, Carol; occupational therapy students; and members of the community; Miles creates colorful abstract expressionist paintings. Collaboration is part of his creative process. In this fifth anniversary issue of OJOT, Occupation and the Artist is following …

Robust Observations Of Land-To-Atmosphere Feedbacks Using The Information Flows Of Fluxnet, Tobias Gerken, Benjamin L. Ruddell, Rong Yu, Paul C. Stoy, Darren T. Drewry

School of Natural Resources: Faculty Publications

Feedbacks between atmospheric processes like precipitation and land surface fluxes including evapotranspiration are difficult to observe, but critical for understanding the role of the land surface in the Earth System. To quantify global surface-atmosphere feedbacks we use results of a process network (PN) applied to 251 eddy covariance sites from the LaThuile database to train a neural network across the global terrestrial surface. There is a strong land–atmosphere coupling between latent (LE) and sensible heat flux (H) and precipitation (P) during summer months in temperate regions, and between H and P during winter, whereas tropical rainforests show little coupling seasonality. …

A Baker's Dozen Of Top Antimicrobial Stewardship Intervention Publications In 2018, Elias B. Chahine, Spencer H. Durham, Krutika N. Mediwala, Daniel B. Chastain, Timothy P. Gauthier, Brandon K. Hill, Bruce M. Jones, Jamie J. Kisgen, Ashley H. Marx, Kayla R. Stover, Marylee V. Worley, Christopher M. Bland, P. Brandon Bookstaver

Faculty and Student Publications

© The Author(s) 2019 Phytochemical investigation of methanolic extract of Limonium leptophyllum (Plumbaginaceae), led to the isolation of 1 new isoflavonoid with a rare 5-membered dihydrofuran ring (1, leptoisoflavone A) and 8 known compounds. The known isolated compounds were identified as euchrenone b9 (2), auriculasin (3), kaempferol (4), avicularoside (5), myrice-tin-3-arabinoside (6), trans-N-feruloyltyramine (7), trans-N-caffeoyltyramine (8), and β-sitosterol (9). The crude methanolic extract exhibited moderate activity toward endocannabinoid receptors. Auriculasin (3) showed activity toward cannabinoid receptor type 1 (86.7% displacement with IC50 8.92 μM).

Retention By Program Fall 2019, Southwestern Oklahoma State University

Student Outcomes

This is a Student Outcome and Retention Report produced by the SWOSU Office of Institutional Research.

Pragmatic Randomised Clinical Trial Of Proton Versus Photon Therapy For Patients With Non-Metastatic Breast Cancer: The Radiotherapy Comparative Effectiveness (Radcomp) Consortium Trial Protocol, Justin E Bekelman, Walter Bosch, Et Al

Open Access Publications

INTRODUCTION: A broad range of stakeholders have called for randomised evidence on the potential clinical benefits and harms of proton therapy, a type of radiation therapy, for patients with breast cancer. Radiation therapy is an important component of curative treatment, reducing cancer recurrence and extending survival. Compared with photon therapy, the international treatment standard, proton therapy reduces incidental radiation to the heart. Our overall objective is to evaluate whether the differences between proton and photon therapy cardiac radiation dose distributions lead to meaningful reductions in cardiac morbidity and mortality after treatment for breast cancer.

METHODS: We are conducting a large …

Ua12/2/1 College Heights Herald, Vol. 95, No. 8, Wku Student Affairs

WKU Administration Documents

WKU campus newspaper reporting campus, athletic and Bowling Green, Kentucky news. This issue contains articles:

• Civil Suit: Ex-WKU Player Accused of Sex Assault – Marlon Hunter
• Burris, Lily. WKU to Be Tobacco-Free, Smoke-Free Campus
• Burris, Lily. Behind the Mask – Big Red, O’Brian McKinley
• Burris, Lily. WKU Expects Freshman Enrollment Drop, University of Kentucky & Murray State University Up
• Dobbs. Jack. Graduate Programs for Criminology, Sociology Set to Be Cut
• Stack, Madalyn. Editorial Cartoon re: Matt Bevin Email
• Schmalbert Schmells – Matt Bevin Email
• Mattison, Reed. Not Horsing Around – Ethan Harrington, Farriers
• Tolbert, Eleanor. Shoot Your Shot – Gun …

2019 October 15 - Medical Student Education Committee Minutes, Medical Student Education Committee, East Tennessee State University

Medical Student Education Committee Minutes

No abstract provided.

Review Of "The Imagination In German Idealism And Romanticism" Edited By G. Gentry And K. Pollok, Richard Thomas Eldridge

Philosophy Faculty Works

No abstract provided.

Genetic Deficiency Or Pharmacological Inhibition Of Mir-33 Protects From Kidney Fibrosis, Nathan L. Price, Veronica Miguel, Wen Ding, Abhishek K. Singh, Shipra Malik, Noemi Rotllan, Anna Moshnikova, Jakub Toczek, Caroline Zeiss, Mehran M. Sadeghi, Noemi Arias, Angel Baldan, Oleg A. Andreev, Diego Rodriguez-Puyol, Raman Bahal, Yana K. Reshetnyak, Yajaira Suarez, Carlos Fernandez-Hernando, Santiago Lamas

Physics Faculty Publications

Previous work has reported the important links between cellular bioenergetics and the development of chronic kidney disease, highlighting the potential for targeting metabolic functions to regulate disease progression. More recently, it has been shown that alterations in fatty acid oxidation (FAO) can have an important impact on the progression of kidney disease. In this work, we demonstrate that loss of miR-33, an important regulator of lipid metabolism, can partially prevent the repression of FAO in fibrotic kidneys and reduce lipid accumulation. These changes were associated with a dramatic reduction in the extent of fibrosis induced in 2 mouse models of …

Multi‐Scale Integration Of Tree Recruitment And Range Dynamics In A Changing Climate, Paige E. Copenhaver-Parry, Charles J. W. Carroll, Patrick H. Martin, Matthew V. Talluto

Faculty Publications - Department of Biological & Molecular Science

Aim: The rate and magnitude of climate‐induced tree range shifts may be influenced by range‐wide variation in recruitment, which acts as a bottleneck in tree range dynamics. Here, we compare range predictions made using standard species distribution models (SDMs) and an integrated metamodelling approach that assimilates data on adult occurrence, seedling recruitment dynamics, and seedling survival under both current and future climate, and evaluate the degree to which information provided by seedling data can improve predictions of range dynamics.

Location: The interior west region of the United States.

Time period: 1990–2015.

Major taxa studied: Five widespread conifer tree species.

Methods: …

Nuclear Tau, P53 And Pin1 Regulate Parn-Mediated Deadenylation And Gene Expression, Jorge Baquero, Sophia Varriano, Martha Ordonez, Pawel Kuczaj, Michael R. Murphy, Gamage Aruggoda, Devon Lundine, Viktoriya Morozova, Ali Elhadi Makki, Alejandra Del C. Alonso, Frida E. Kleiman

Publications and Research

While nuclear tau plays a role in DNA damage response (DDR) and chromosome relaxation, the mechanisms behind these functions are not fully understood. Here, we show that tau forms complex(es) with factors involved in nuclear mRNA processing such as tumor suppressor p53 and poly(A)-specific ribonuclease (PARN) deadenylase. Tau induces PARN activity in different cellular models during DDR, and this activation is further increased by p53 and inhibited by tau phosphorylation at residues implicated in neurological disorders. Tau’s binding factor Pin1, a mitotic regulator overexpressed in cancer and depleted in Alzheimer’s disease (AD), also plays a role in the activation of …

2019-2020 Common Data Set - Wright State University Dayton Campus, Office Of Institutional Research & Effectiveness, Wright State University, Princeton Review

Common Data Set

The 2019-2020 Common Data Set of Wright State University Dayton Campus from the Princeton Review. It includes data on admissions, student enrollment, faculty, class size, financial aid and other measures, using standard definitions that aid comparisons between schools.

2019-2020 Common Data Set - Wright State University Lake Campus, Office Of Institutional Research & Effectiveness, Wright State University, Princeton Review

Common Data Set

The 2019-2020 Common Data Set of Wright State University Lake Campus from the Princeton Review. It includes data on admissions, student enrollment, faculty, class size, financial aid and other measures, using standard definitions that aid comparisons between schools.

Prevalence Of And Factors Associated With Female Sexual Dysfunction Among Women Using Hormonal And Non-Hormonal Contraception At The Aga Khan University Hospital Nairobi, Momin Butt, Valentino Lema, Abraham Mukaindo, Gulnaz Mohamoud, Jacob Shabani

Family Medicine, East Africa

Background: Female sexual function (FSD) is a complex phenomenon. It integrates all body systems and is influenced by a variety of factors. Contraceptives have shown to have variable effects on FSD. In Kenya, the majority of women use hormonal contraception with high rates of discontinuation of use, attributed to related side effects such as weight loss and loss of libido.

Aim: To determine the prevalence of and the factors affecting FSD among women using contraception in our setting.

Setting: The study was carried out at the Aga Khan University Hospital, Nairobi, at various clinical sites.

Methods: A cross-sectional study was …

Environmentally Persistent Free Radicals: Linking Air Pollution And Poor Respiratory Health?, Peter D. Sly, Stephania A. Cormier, Slawomir Lomnicki, Jeffrey N. Harding, Keith Grimwood, Griffith University

Faculty Publications

No abstract provided.

Gardner-Webb University Inducts Seven Into Gallery Of Distinguished Alumni, Office Of University Communications

Gardner-Webb NewsCenter Archive

Gardner-Webb honored outstanding members of the University family with induction into the GWU Gallery of Distinguished Alumni during 2019 Homecoming activities Oct. 11-12. Seven alumni were recognized as new members of the prestigious gallery, including Susan Bolt Briggs, of Gastonia, N.C., Porsha Russell, of Charlotte, N.C., Dr. Michelle Skipper, of St. Pauls, N.C., Mark Edward Smith, of Marvin, N.C., Dr. Manny Trujillo, of Spartanburg, S.C., Keon Williams Jr., of Charlotte, N.C., and Archie Wood, of Yadkinville, N.C.

Production Of Dynein And Kinesin Motor Ensembles On Dna Origami Nanostructures For Single Molecule Observation, Jingjie Hu, Nathan Derr

Biological Sciences: Faculty Publications

Summary

The goal of this protocol is to form ensembles of molecular motors on DNA origami nanostructures and observe the ensemble motility using total internal reflection fluorescence microscopy.

Abstract

Cytoskeletal motors are responsible for a wide variety of functions in eukaryotic cells, including mitosis, cargo transport, cellular motility, and others. Many of these functions require motors to operate in ensembles. Despite a wealth of knowledge about the mechanisms of individual cytoskeletal motors, comparatively less is known about the mechanisms and emergent behaviors of motor ensembles, examples of which include changes to ensemble processivity and velocity with changing motor number, location, …

How Protein - Protein Interactions Contribute To Pyrenoid Formation In Chlamydomonas, Ananya Mukherjee, James V. Moroney

Faculty Publications

© The Author(s) 2019. The chloroplast pyrenoid, an important component of the CO2 concentrating mechanism of algae, is a structure composed primarily of Rubisco. In Chlamydomonas, Rubisco in the pyrenoid is held together by the linker protein EPYC1. Atkinson et al., (2019) determined the regions of the Rubisco small subunit and EPYC1 that are important for the protein-protein interaction, thus making progress towards reconstruction of a pyrenoid in higher plants. Why is a protein soluble in one organism while its homologue in another species becomes part of a liquidlike cell structure? That is the question being addressed by Atkinson et …

Wearable Augmented Reality Application For Shoulder Rehabilitation, Giuseppe Turini, Sara Condino, Rosanna Viglialoro, Marco Gesi, Vincenzo Ferrari

Computer Science Publications

Augmented reality (AR) technology is gaining popularity and scholarly interest in the rehabilitation sector because of the possibility to generate controlled, user-specific environmental and perceptual stimuli which motivate the patient, while still preserving the possibility to interact with the real environment and other subjects, including the rehabilitation specialist. The paper presents the first wearable AR application for shoulder rehabilitation, based on Microsoft HoloLens, with real-time markerless tracking of the user’s hand. Potentialities and current limits of commercial head-mounted displays (HMDs) are described for the target medical field, and details of the proposed application are reported. A serious game was designed …

Daily Eastern News: October 15, 2019, Eastern Illinois University

October

No abstract provided.

Body Weight And General Health Among Female Breast Cancer Survivors, Quiping (Pearl) Zhou, Kathleen Griffith, Sherrie Flynt Wallington

Biennial Convention (CONV)

Overweight and obese breast cancer survivors reported lower general health than women with normal weight. Significant predictors for perceived fair poor health include number of comorbidities income, education, and physical activities or excise in the past 30 days.