Digital Commons Network^™

Direct-To-Patient Survey For Diagnosis Of Benign Paroxysmal Positional Vertigo, Heidi Richburg, Richard J. Povinelli, David Friedland

Electrical and Computer Engineering Faculty Research and Publications

Given the high incidence of dizziness and its frequent misdiagnosis, we aim to create a clinical support system to classify the presence or absence of benign paroxysmal positional vertigo with high accuracy and specificity. This paper describes a three-phase study currently underway for classification of benign paroxysmal positional vertigo, which includes diagnosis by a specialist in a clinical setting. Patient background information is collected by a survey on an Android tablet and machine learning techniques are applied for classification. Decision trees and wrappers are employed for their ability to provide information about the question set. One goal of the study …

The Genetic And Epigenetic Effects Of Pre-Treatment With The Small Molecule Inhibitors Chir99021, Pd0325901, And Nup0178 On Bovine Fetal Fibroblast Cells, Laura Whitney Coley

LSU Doctoral Dissertations

The ability to produce genetically superior livestock has established somatic cell nuclear transfer (SCNT) as an invaluable tool in commercial livestock production. Successful reprogramming of somatic cells towards pluripotency requires the epigenetic marks characteristic of the differentiated cell type first be erased in order to inactivate the somatic cell program and activate the embryonic program. Several small molecules have been shown to improve both the kinetics and efficiency of reprogramming. These chemical modifiers aid in overcoming the “roadblocks” encountered during the reprogramming process by inducing the necessary epigenetic modifications needed to silence the somatic cell genome and completely reactivate the …

Beach Recovery From Extreme Storm Activity During The 2013–14 Winter Along The Atlantic Coast Of Europe, Guillaume Dodet, Bruno Castelle, Gerd Masselink, Timothy Scott, Mark Davidson, France Floc'h, Derek Jackson, Serge Suanez

School of Biological and Marine Sciences

The storm sequence of the 2013–14 winter left many beaches along the Atlantic coast of Europe in their most eroded state for decades. Understanding how beaches recover from such extreme events is essential for coastal managers, especially in light of potential regional increases in storminess due to climate change. Here we analyse a unique dataset of decadal beach morphological changes along the west coast of Europe to investigate the post-2013–14 winter recovery. We show that the recovery signature is site specific and multi-annual, with one studied beach fully recovered after 2 years, and the others only partially recovered after 4 …

Inside Nano: A Systems Biology Framework To Contextualize The Mechanism-Of-Action Of Engineered Nanomaterials, A Serra, I Letunic, V Fortino, Rd Handy, B Fadeel, R Tagliaferri, D Greco

School of Biological and Marine Sciences

No abstract provided.

Protocol For A Feasibility Randomised Controlled Trial Of Targeted Oxygen Therapy In Mechanically Ventilated Critically Ill Patients, Daniel S. Martin, Chris Brew-Graves, Neil Mccartan, Gavin Jell, Ingrid Potyka, Jia Stevens, Norman R. Williams, Margaret Mcneil, Br O’Driscoll, Monty Mythen, Michael P.W. Grocott

Peninsula Medical School

IntroductionOxygen is the most commonly administered drug to mechanically ventilated critically ill adults, yet little is known about the optimum oxygen saturation (SpO2) target for these patients; the current standard of care is an SpO2of 96% or above. Small pilot studies have demonstrated that permissive hypoxaemia (aiming for a lower SpO2than normal by using a lower fractional inspired oxygen concentration (FIO2)) can be achieved in the critically ill and appears to be safe. This approach has not been evaluated in a National Health Service setting. It is possible that permissive hypoxaemia may be beneficial to critically ill patients thus it …

Effects Of Substrate On Movement Patterns And Behavior Of Stream Fish Through Culverts: An Experimental Approach, Kyla Johnson, Lindsay E. Wait, Suzanne K. Monk, Russell Rader, Rollin H. Hotchkiss, Mark C. Belk

Faculty Publications

Culverts can provide a significant barrier to fish passage by fragmenting fish habitats and impeding the passage success of small-bodied fish. Geographical connectivity is critical to the maintenance of diverse fish assemblages. Culverts with high cross-sectional velocity can cause population fragmentation by impeding passage of small, freshwater fish. Behavioral responses of small fish to high velocities can differ among functional groups, and swimming behavior of many species is not well known. We tested effects of substrate type on swimming behavior in two small, freshwater fish species—southern leatherside chub (Lepidomeda aliciae, a midwater species), and longnose dace (Rhinichthys …

Marine Renewable Energy Law And Policy In The Bay Of Fundy: The Impact Of Ambiguous Domestic Boundaries In Canada On Nova Scotia's Regulatory Framework, Esteban Salcedo

Ocean and Coastal Law Journal

Using a legal history methodology, this paper examines existing marine renewable energy law and policy in Nova Scotia with a focus on its application in the Bay of Fundy. This paper critically assesses the current approach to coastal management in light of recent recommendations summarized in the Fournier report. This paper argues that, despite clear calls to develop integrated ocean management and marine spatial planning in policies and regulations, Canada and Nova Scotia have failed to do so because of unclear federal-provincial boundaries. Ambiguous domestic borders in the Bay of Fundy have been at the source of an overly cautious, …

The Collegian: January 16, 2019, The Collegian Staff, South Dakota State University

The Collegian, 2018-2019

Volume: 134

Issue: 14

Maintaining Stability In A Changing Climate: A Comparative Analysis Of Public Health Systems And Migration Policies In The U.S. And Canada, Laura Cutlip

Climate and Society

This paper examines the relation between climate change, migration, and public health to better understand how the United States health system is positioned to deal with likely challenges to human health posed by environmental changes. The author reviews probable impacts of climate change on population displacement and disease before considering how the current structure of the health system of the United States will render it unable to adapt to these changes and challenges. The Canadian health care system and refugee policies are then reviewed to provide a counterpoint to this analysis. These findings are then considered in tandem as the …

Templated Macroporous Polyethylene Glycol Hydrogels For Spheroid And Aggregate Cell Culture, Mozhdeh Imaninezhad, Lindsay Hill, Grant Kolar, Kyle Vogt, Silviya Petrova Zustiak

Biological Sciences Faculty Research & Creative Works

Macroporous cell-laden hydrogels have recently gained recognition for a wide range of biomedical and bioengineering applications. There are various approaches to create porosity in hydrogels, including lyophilization or foam formation. However, many do not allow a precise control over pore size or are not compatible with in situ cell encapsulation. Here, we developed novel templated macroporous hydrogels by encapsulating uniform degradable hydrogel microspheres produced via microfluidics into a hydrogel slab. The microspheres degraded completely leaving macropores behind. Microsphere degradation was dependent on the incubation medium, microsphere size, microsphere confinement in the hydrogel as well as cell encapsulation. Uniquely, the degradable …

Open-Source Automated Chemical Vapor Deposition System For The Production Of Two-Dimensional Nanomaterials, Lizandra Williams-Godwin, Dale Brown, Richard Livingston, Tyler Webb, Lynn Karriem, Elton Graugnard, David Estrada

Materials Science and Engineering Faculty Publications and Presentations

The study of two- dimensional (2D) materials is a rapidly growing area within nanomaterials research. However, the high equipment costs, which include the processing systems necessary for creating these materials, can be a barrier to entry for some researchers interested in studying these novel materials. Such process systems include those used for chemical vapor deposition, a preferred method for making these materials. To address this challenge, this article presents the first open-source design for an automated chemical vapor deposition system that can be built for less than a third of the cost for a comparable commercial system. The materials and …

Standards For Distribution Models In Biodiversity Assessments, Miguel B. Araújo, Robert P. Anderson, A. Márcia Barbosa, Colin M. Beale, Carsten F. Dormann, Regan Early, Raquel A. Garcia, Antoine Guisan, Luigi Maiorano, Babak Naimi, Robert B. O'Hara, Niklaus E. Zimmermann, Carsten Rahbek

Publications and Research

Demand for models in biodiversity assessments is rising, but which models are adequate for the task? We propose a set of best-practice standards and detailed guidelines enabling scoring of studies based on species distribution models for use in biodiversity assessments. We reviewed and scored 400 modeling studies over the past 20 years using the proposed standards and guidelines. We detected low model adequacy overall, but with a marked tendency of improvement over time in model building and, to a lesser degree, in biological data and model evaluation. We argue that implementation of agreed-upon standards for models in biodiversity assessments would …

New Genomic Ecology Of Coastal Organisms Program: Unh And Umaine Partner For Research, Lori Taylor Gula

UNH Today Archive

No abstract provided.

Demethylation By Low-Dose 5-Aza-2'-Deoxycytidine Impairs 3d Melanoma Invasion Partially Through Mir-199a-3p Expression Revealing The Role Of This Mir In Melanoma., Cécile Desjobert, Arnaud Carrier, Audrey Delmas, Diego M Marzese, Antoine Daunay, Florence Busato, Arnaud Pillon, Jörg Tost, Joëlle Riond, Gilles Favre, Chantal Etievant, Paola B Arimondo

Articles, Abstracts, and Reports

BACKGROUND: Efficient treatments against metastatic melanoma dissemination are still lacking. Here, we report that low-cytotoxic concentrations of 5-aza-2'-deoxycytidine, a DNA demethylating agent, prevent in vitro 3D invasiveness of metastatic melanoma cells and reduce lung metastasis formation in vivo.

RESULTS: We unravelled that this beneficial effect is in part due to MIR-199A2 re-expression by promoter demethylation. Alone, this miR showed an anti-invasive and anti-metastatic effect. Throughout integration of micro-RNA target prediction databases with transcriptomic analysis after 5-aza-2'-deoxycytidine treatments, we found that miR-199a-3p downregulates set of genes significantly involved in invasion/migration processes. In addition, analysis of data from melanoma patients showed a …

Daily Eastern News: January 16, 2019, Eastern Illinois University

January

No abstract provided.

Hotline Press Newspaper- Jan 16 ,2019 Vol 34 No 40, Hotline Press Newspaper

Hotline Press Newspaper 2019

No abstract provided.

Model-Based Virtual Patient Analysis Of Human Liver Regeneration Predicts Critical Perioperative Factors Controlling The Dynamic Mode Of Response To Resection., Babita Verma, Pushpavanam Subramaniam, Rajanikanth Vadigepalli

Department of Pathology, Anatomy, and Cell Biology Faculty Papers

BACKGROUND: Liver has the unique ability to regenerate following injury, with a wide range of variability of the regenerative response across individuals. Existing computational models of the liver regeneration are largely tuned based on rodent data and hence it is not clear how well these models capture the dynamics of human liver regeneration. Recent availability of human liver volumetry time series data has enabled new opportunities to tune the computational models for human-relevant time scales, and to predict factors that can significantly alter the dynamics of liver regeneration following a resection.

METHODS: We utilized a mathematical model that integrates signaling …

Concept Inventories As A Resource For Teaching Evolution, Robert E. Furrow, Jeremy L. Hsu

Biology, Chemistry, and Environmental Sciences Faculty Articles and Research

Understanding evolution is critical to learning biology, but few college instructors take advantage of the body of peer-reviewed literature that can inform evolution teaching and assessment. Here we summarize the peer-reviewed papers on tools to assess student learning of evolutionary concepts. These published concept inventories provide a resource for instructors to design courses, gauge student preparation, identify key misconceptions in their student population, and measure the impact of a lesson, course, or broader curriculum on student learning. Because these inventories vary in their format, target audience, and degree of validation, we outline and explain these features. In addition to summarizing …

Global Papers On Supreme Court Judgments During 2000-2016: A Bibliometric Study, Banalata Pradhan Mrs, Annapurna Pattnaik

Library Philosophy and Practice (e-journal)

This paper analyses the growth and development of productivity in Supreme Court Judgments Worldwide during the period 2000-2016, data extracted from Scopus database. The focus of the study is on highest producing countries and institutions engaged in research and their impact on the society. The study shows that the World output in Supreme Court judgments has grown continuously during the period of study but in an inconsistent way. USA contributed highest 49.64% papers to the total World’s output followed by UK and Canada. Only a small proportion (35.99%) remains uncited during the period of study.

Informed Consent: No Longer Just What The Doctor Ordered? Revisited, Marc D. Ginsberg

Akron Law Review

The law of informed consent in medicine has evolved from the original doctrine which required the physician’s disclosure of the risks, benefits, and complications of (and alternatives to) a proposed procedure or treatment. The doctrine now implicates the disclosure of matters personal to the physician. Questions regarding the breadth of the doctrine in other respects have developed as well. This paper represents the author’s second examination of the unconventional aspects of the law of informed consent.

The Role Of Occupational Therapy In Functional Literacy, Lenin C. Grajo, Sharon A. Gutman

The Open Journal of Occupational Therapy

In this Opinions in the Profession article we aim to uniquely articulate the distinct value of and need for functional literacy development in the clients we serve. Functional literacy, as coined in this article, is the ability to interpret common written materials needed to effectively carry out basic daily life skills and participate in meaningful occupations and social roles. We propose three specific strategies through which occupational therapists, across practice settings, developmental stages, and populations, can assume active roles in literacy support as it is embedded in occupation: literacy (a) as a form of occupational justice promotion; (b) as an …

The Effects Of The Leisure Activity Of Coloring On Post-Test Anxiety In Graduate Level Occupational Therapy Students, Brittney N. Burton, Mary F. Baxter

The Open Journal of Occupational Therapy

Background: This study examined the effects of the leisure activity of coloring on the anxiety levels of graduate level occupational therapy students after taking a high stress exam. This study also examined the effects of the leisure activity of coloring on the students’ perceptions of preparedness for and performance on the exam.

Method: The participants were recruited for this quantitative, pre/posttest study through a purposive convenience sample and randomly assigned to either the leisure activity or the control. A self-report assessment was used for data collection. The changes in anxiety levels were examined using a repeated measures analysis …

Iron (Oxyhydr)Oxides Serve As Phosphate Traps In Tundra And Boreal Peat Soils, Elizabeth M. Herndon, Lauren Kinsman-Costello, Kiersten A. Duroe, Jonathan Mills, Evan Kane, Stephen D. Sebestyen, Aaron A. Thompson, Stan D. Wullschleger

College of Forest Resources and Environmental Science Publications

Arctic and boreal ecosystems are experiencing pronounced warming that is accelerating decomposition of soil organic matter and releasing greenhouse gases to the atmosphere. Future carbon storage in these ecosystems depends on the balance between microbial decomposition and primary production, both of which can be regulated by nutrients such as phosphorus. Phosphorus cycling in tundra and boreal regions is often assumed to occur through biological pathways with little interaction with soil minerals; that is, phosphate released from organic molecules is rapidly assimilated by plants or microorganisms. In contrast to this prevailing conceptual model, we use sequential extractions and spectroscopic techniques to …

Students Leading Effort To Measure Sustainability At Rwu, Courtney Dell’Agnese, Jill Rodrigues

Featured News Story

With sustainability embraced as a university mission and campus culture, students are tracking and evaluating how Roger Williams University measures up in making greater strides toward sustainability from energy conservation to teaching concepts.

Environmental Ethics And Biodiversity Principles, Z. Abduazimova

Central Asian Problems of Modern Science and Education

The article discusses the basic principles of environmental ethics and the characteristics of the principle of biodiversity. The principle of biodiversity has the characteristic features of elevating moral values regarding the moral and 89 caring attitude of a person to the world around. The article describes the main directions of environmental ethics and principles of biodiversity. Biological diversity is the diversity of all life on Earth, from gene-based ecosystems, including all types of animals, plants and microorganisms that inhabit all the habitats of the planet. It "permeates" each of the three main levels of the organization of living matter, hence …

Natural Distribution Of The Algae Plant Of The Treatment Of Telearosovodis, Systematic Place And Separate Biological Features, Ch. H. Kuchkarova

Central Asian Problems of Modern Science and Education

The present research works at the Andijan Municipal Water Treatment Plant Joint Stock Company recommendations were made to use Pistia Telezorovid, a high-water plant, to effectively neutralize the waste water in order to improve the biological treatment of communal waste water, which is the main treatment.

Baysun-Chulbair Mountains Are Unique Natural And Territorial Complex, M. A. Kholmurodov, D. N. Kodirova, Z. M. Kurbonova

Central Asian Problems of Modern Science and Education

The richness of the phytocenotic, floristic diversity of the vegetation cover of the Baysun-Chulbair Mountains is in accordance with the general natural law, ie its geographical, orographic, geological, hydrological, climatic and soil types, sea level and mountain slopes expositions, the harmony of the taxonomic units historically formed by the plant communities associated with them, ie because of the biogeocenosis complex were found and evaluated in the size of the independent district.

Hygienic Substantiation Of Alimentary Prevention Of Mastopathy, G. A. Toshmatova

Central Asian Problems of Modern Science and Education

Our survey indicates that there is a link between the process of risi ng of danger of mastopathie and medico-biologic actions. The followings are the most important actions: late beginning of "mehrane" (i n 15-17 years),late pregnancy, unnatural stopping the pregnancy, unnaturally nursing the baby or shortly nursing, soft or internal diseases (roting of genitalias and various types of illnesses related to sack-shaped tumour) existing, irregular sexual life, excessive bigness of "TVI", puberty and traumas in bust. Early founding out the mastophie can help to prevent and have a prophylactic works on it

Chronic Gastritis And Carcinogenesis Issues, G. N. Sobirova, U. K. Abdullaeva

Central Asian Problems of Modern Science and Education

In the review risk factors which transformations chronic atrophic a gastritis in a stomach cancer promote are analyzed. The characteristic of precancer conditions as increase in risk of development of a cancer of a stomach is given. As risk factor of a cancer of a stomach definition of subtypes intestinal metaplasia is offered, dividing on full and incomplete taking into account decrease in an expression gastric mucin MUC1, MUC5AC and MUC6. The role of a genetic susceptibility of an organism to infected Н pylori, the factors of its pathogenicity promoting metaplasia epithelium is analyzed. Also role Toll-like of receptors 4 …

The Collegian: January 15, 2019, The Collegian Staff, South Dakota State University

The Collegian, 2019-2020

Volume: 135

Issue: 12