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2019

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Articles 18721 - 18750 of 29728

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Electromagnon Excitation In Cupric Oxide Measured By Fabry-Pérot Enhanced Terahertz Mueller Matrix Ellipsometry, Sean Knight, Dharmalingam Prabhakaran, Christian Binek, Mathias Schubert Feb 2019

Electromagnon Excitation In Cupric Oxide Measured By Fabry-Pérot Enhanced Terahertz Mueller Matrix Ellipsometry, Sean Knight, Dharmalingam Prabhakaran, Christian Binek, Mathias Schubert

Christian Binek Publications

Here we present the use of Fabry-Pérot enhanced terahertz (THz) Mueller matrix ellipsometry to measure an electromagnon excitation in monoclinic cupric oxide (CuO). As a magnetically induced ferroelectric multiferroic, CuO exhibits coupling between electric and magnetic order. This gives rise to special quasiparticle excitations at THz frequencies called electromagnons. In order to measure the electromagnons in CuO, we exploit single-crystal CuO as a THz Fabry-Pérot cavity to resonantly enhance the excitation’s signature. This enhancement technique enables the complex index of refraction to be extracted. We observe a peak in the absorption coefficient near 0.705 THz and 215 K, which corresponds …

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Dynamics And Selective Remodeling Of The Dna-Binding Domains Of Rpa, Nilisha Pokhrel, Colleen C. Caldwell, Elliot I. Corless, Emma A. Tillison, Joseph Tibbs, Nina Jocic, S. M. Ali Tabei, Marc S. Wold, Maria Spies, Edwin Antony Feb 2019

Dynamics And Selective Remodeling Of The Dna-Binding Domains Of Rpa, Nilisha Pokhrel, Colleen C. Caldwell, Elliot I. Corless, Emma A. Tillison, Joseph Tibbs, Nina Jocic, S. M. Ali Tabei, Marc S. Wold, Maria Spies, Edwin Antony

Biological Sciences Faculty Research and Publications

Replication protein A (RPA) coordinates important DNA metabolic events by stabilizing single-stranded DNA (ssDNA) intermediates, activating the DNA-damage response and handing off ssDNA to the appropriate downstream players. Six DNA-binding domains (DBDs) in RPA promote high-affinity binding to ssDNA yet also allow RPA displacement by lower affinity proteins. We generated fluorescent versions of Saccharomyces cerevisiae RPA and visualized the conformational dynamics of individual DBDs in the context of the full-length protein. We show that both DBD-A and DBD-D rapidly bind to and dissociate from ssDNA while RPA remains bound to ssDNA. The recombination mediator protein Rad52 selectively modulates the dynamics …

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Against The Young, Starry Background: A Critical Analysis Of A Creative Work In The Context Of Its Genres, Todd Kleiboer Feb 2019

Against The Young, Starry Background: A Critical Analysis Of A Creative Work In The Context Of Its Genres, Todd Kleiboer

Honors Theses

No abstract provided.

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Gene Therapy Targeting Sarm1 Blocks Pathological Axon Degeneration In Mice, Stefanie Geisler, Shay X. Huang, Amy Strickland, Ryan A. Doan, Daniel W. Summers, Xianrong Mao, Jiwoong Park, Aaron Diantonio, Jeffrey Milbrandt Feb 2019

Gene Therapy Targeting Sarm1 Blocks Pathological Axon Degeneration In Mice, Stefanie Geisler, Shay X. Huang, Amy Strickland, Ryan A. Doan, Daniel W. Summers, Xianrong Mao, Jiwoong Park, Aaron Diantonio, Jeffrey Milbrandt

Open Access Publications

Axonal degeneration (AxD) following nerve injury, chemotherapy, and in several neurological disorders is an active process driven by SARM1, an injury-activated NADase. Axons of SARM1-null mice exhibit greatly delayed AxD after transection and in models of neurological disease, suggesting that inhibiting SARM1 is a promising strategy to reduce pathological AxD. Unfortunately, no drugs exist to target SARM1. We, therefore, developed SARM1 dominant-negatives that potently block AxD in cellular models of axotomy and neuropathy. To assess efficacy in vivo, we used adeno-associated virus-mediated expression of the most potent SARM1 dominant-negative and nerve transection as a model of severe AxD. While axons …

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Identification Of Novel Regulatory Genes In Apap Induced Hepatocyte Toxicity By A Genome-Wide Crispr-Cas9 Screen., Katherine Shortt, Daniel P. Heruth, Nini Zhang, Weibin Wu, Shipra Singh, Ding-You Li, Li Qin Zhang, Gerald J. Wyckoff, Lei S Qi, Craig A. Friesen, Shui Qing Ye Feb 2019

Identification Of Novel Regulatory Genes In Apap Induced Hepatocyte Toxicity By A Genome-Wide Crispr-Cas9 Screen., Katherine Shortt, Daniel P. Heruth, Nini Zhang, Weibin Wu, Shipra Singh, Ding-You Li, Li Qin Zhang, Gerald J. Wyckoff, Lei S Qi, Craig A. Friesen, Shui Qing Ye

Manuscripts, Articles, Book Chapters and Other Papers

Acetaminophen (APAP) is a commonly used analgesic responsible for more than half of acute liver failure cases. Identification of previously unknown genetic risk factors would provide mechanistic insights and novel therapeutic targets for APAP-induced liver injury. This study used a genome-wide CRISPR-Cas9 screen to evaluate genes that are protective against, or cause susceptibility to, APAP-induced liver injury. HuH7 human hepatocellular carcinoma cells containing CRISPR-Cas9 gene knockouts were treated with 15 mM APAP for 30 minutes to 4 days. A gene expression profile was developed based on the 1) top screening hits, 2) overlap of expression data from APAP overdose studies, …

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Size-Selective Harvesting And Individual Personality In A Social Fish, V Sbragaglia, J Alós, K Fromm, C Monk, C Díaz-Gil, S Uusi-Heikkilä, A Honsey, A Wilson, R Arlinghaus Feb 2019

Size-Selective Harvesting And Individual Personality In A Social Fish, V Sbragaglia, J Alós, K Fromm, C Monk, C Díaz-Gil, S Uusi-Heikkilä, A Honsey, A Wilson, R Arlinghaus

School of Biological and Marine Sciences

No abstract provided.

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The Effects Of Ocular Dominance On Visual Processing In College Students, William Alexander Holland Feb 2019

The Effects Of Ocular Dominance On Visual Processing In College Students, William Alexander Holland

James Madison Undergraduate Research Journal (JMURJ)

The role of ocular dominance in processing visual memory and analytic tasks is unknown. Research has variably showed both significant effects and no effect of ocular dominance on visual perception, motor control, and sports performance. The goal of this study was to determine if there is a relationship between ocular dominance and visual processing under a variety of computer gaming tasks. This was accomplished by first determining subjects’ ocular dominance through the Miles test, and then examining the subjects’ visual performance on four different Lumosity games under three conditions: left eye, right eye, and both eyes. Results suggest a relationship …

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Biologists Lure Long Horned Beetles To Diversity Study In Romania, Ohio University College Of Arts & Sciences Feb 2019

Biologists Lure Long Horned Beetles To Diversity Study In Romania, Ohio University College Of Arts & Sciences

All Forum Articles

No abstract provided.

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Wosu Talks To Mccarthy About American Chestnut, Ohio University College Of Arts & Sciences Feb 2019

Wosu Talks To Mccarthy About American Chestnut, Ohio University College Of Arts & Sciences

All Forum Articles

No abstract provided.

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Alumni News | Lyons To Expand Focal Pointe Eye Care, Ohio University College Of Arts & Sciences Feb 2019

Alumni News | Lyons To Expand Focal Pointe Eye Care, Ohio University College Of Arts & Sciences

All Forum Articles

No abstract provided.

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Nutrient Acquisition Strategies Augment Growth In Tropical N2‐Fixing Trees In Nutrient‐Poor Soil And Under Elevated Co2, Megan K. Nasto, Klaus Winter, Benjamin L. Turner, Cory C. Cleveland Feb 2019

Nutrient Acquisition Strategies Augment Growth In Tropical N2‐Fixing Trees In Nutrient‐Poor Soil And Under Elevated Co2, Megan K. Nasto, Klaus Winter, Benjamin L. Turner, Cory C. Cleveland

Ecology Center Publications

Tropical forests play a dominant role in the global carbon (C) cycle, and models predict increases in tropical net primary productivity (NPP) and C storage in response to rising atmospheric carbon dioxide (CO2) concentrations. The extent to which increasing CO2 will enhance NPP depends in part on the availability of nitrogen (N) and phosphorus (P) to support growth. Some tropical trees can potentially overcome nutrient limitation by acquiring N via symbiotic dinitrogen (N2) fixation, which may provide a benefit in acquiring P via investment in N‐rich phosphatase enzymes or arbuscular mycorrhizal (AM) fungi. We conducted …

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Alumni News | Fischer Is Obstetrician And Gynecologist With Trihealth, Ohio University College Of Arts & Sciences Feb 2019

Alumni News | Fischer Is Obstetrician And Gynecologist With Trihealth, Ohio University College Of Arts & Sciences

All Forum Articles

No abstract provided.

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Propolis Or Caffeic Acid Phenethyl Ester (Cape) Inhibits Growth And Viability In Multiple Oral Cancer Cell Lines, Wendy Saarem, Fang Wu Yang, Elena Farfel Feb 2019

Propolis Or Caffeic Acid Phenethyl Ester (Cape) Inhibits Growth And Viability In Multiple Oral Cancer Cell Lines, Wendy Saarem, Fang Wu Yang, Elena Farfel

Dental Medicine Faculty Research

Objective: Propolis is a natural antimicrobial resin from honeybee hives that contains caffeic acid phenethyl ester (CAPE), which has anti-proliferative activity against some human cancers, including colon, liver, lung and breast – although limited evidence has evaluated this potential in oral cancers. Based upon this information, the primary objective of this study was to evaluate the anti-tumor effects of CAPE against multiple well-characterized oral cancer cell lines. Methods: Using well-characterized oral cancer cell lines (SCC15, SCC25 and CAL27), CAPE was administered at 100 ug/mL to assess any effects on cellular viability or growth over three days. A normal, non-cancerous cell …

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Decoding Attentional State To Faces And Scenes Using Eeg Brainwaves, Reza Abiri, Soheil Borhani, Yang Jiang, Xiaopeng Zhao Feb 2019

Decoding Attentional State To Faces And Scenes Using Eeg Brainwaves, Reza Abiri, Soheil Borhani, Yang Jiang, Xiaopeng Zhao

Behavioral Science Faculty Publications

Attention is the ability to facilitate processing perceptually salient information while blocking the irrelevant information to an ongoing task. For example, visual attention is a complex phenomenon of searching for a target while filtering out competing stimuli. In the present study, we developed a new Brain-Computer Interface (BCI) platform to decode brainwave patterns during sustained attention in a participant. Scalp electroencephalography (EEG) signals using a wireless headset were collected in real time during a visual attention task. In our experimental protocol, we primed participants to discriminate a sequence of composite images. Each image was a fair superimposition of a scene …

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Increasing Salt Rejection Of Polybenzimidazole Nanofiltration Membranes Via The Addition Of Immobilized And Aligned Aquaporins, Priyesh Ashokrao Wagh, Xinyi Zhang, Ryan Blood, Peter M. Kekenes-Huskey, Prasangi Rajapaksha, Yinan Wei, Isabel C. Escobar Feb 2019

Increasing Salt Rejection Of Polybenzimidazole Nanofiltration Membranes Via The Addition Of Immobilized And Aligned Aquaporins, Priyesh Ashokrao Wagh, Xinyi Zhang, Ryan Blood, Peter M. Kekenes-Huskey, Prasangi Rajapaksha, Yinan Wei, Isabel C. Escobar

Chemical and Materials Engineering Faculty Publications

Aquaporins are water channel proteins in cell membrane, highly specific for water molecules while restricting the passage of contaminants and small molecules, such as urea and boric acid. Cysteine functional groups were installed on aquaporin Z for covalent attachment to the polymer membrane matrix so that the proteins could be immobilized to the membranes and aligned in the direction of the flow. Depth profiling using x-ray photoelectron spectrometer (XPS) analysis showed the presence of functional groups corresponding to aquaporin Z modified with cysteine (Aqp-SH). Aqp-SH modified membranes showed a higher salt rejection as compared to unmodified membranes. For 2 M …

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Biogeochemical Recuperation Of Lowland Tropical Forest During Succession, Benjamin W. Sullivan, Rachel L. Nifong, Megan K. Nasto, Silvia Alvarez-Clare, Camie M. Dencker, Fiona M. Soper, Kevin T. Shoemaker, F. Yoko Ishida, Joana Zaragoza-Castells, Eric A. Davidson, Cory C. Cleveland Feb 2019

Biogeochemical Recuperation Of Lowland Tropical Forest During Succession, Benjamin W. Sullivan, Rachel L. Nifong, Megan K. Nasto, Silvia Alvarez-Clare, Camie M. Dencker, Fiona M. Soper, Kevin T. Shoemaker, F. Yoko Ishida, Joana Zaragoza-Castells, Eric A. Davidson, Cory C. Cleveland

Biology Faculty Publications

High rates of land conversion and land use change have vastly increased the proportion of secondary forest in the lowland tropics relative to mature forest. As secondary forests recover following abandonment, nitrogen (N) and phosphorus (P) must be present in sufficient quantities to sustain high rates of net primary production and to replenish the nutrients lost during land use prior to secondary forest establishment. Biogeochemical theory and results from individual studies suggest that N can recuperate during secondary forest recovery, especially relative to P. Here, we synthesized 23 metrics of N and P in soil and plants from 45 secondary …

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Ecological Response Of Phytoplankton To The Oil Spills In The Oceans, Danling Tang, Jing Sun, Li Zhou, Sufen Wang, Ramesh P. Singh, Gang Pan Feb 2019

Ecological Response Of Phytoplankton To The Oil Spills In The Oceans, Danling Tang, Jing Sun, Li Zhou, Sufen Wang, Ramesh P. Singh, Gang Pan

Mathematics, Physics, and Computer Science Faculty Articles and Research

Oil spills in oceans have substantial influence on marine ecosystems. This study investigates 21 oil spills in the world. Analyzing Chlorophyll-a (Chl-a) from Moderate Resolution Imaging Spectroradiomerer (MODIS) data after Penglai oil spills on 4 June 2011, found a bloom with peak value of Chl-a (13.66 mg m−3) spread over an area of 800 km2 during 18–25 June 2011, and a pronounced increase in the monthly Chl-a concentration (6.40 mg m−3) on June 2012 in the Bohai Sea. Out of the 21 oil spills, 14 blooms were observed, while 11 …

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Rn181 Is A Tumour Suppressor In Gastric Cancer By Regulation Of The Erk/Mapk–Cyclin D1/Cdk4 Pathway, S Wang, X Wang, Y Gao, Y Peng, Et Al Feb 2019

Rn181 Is A Tumour Suppressor In Gastric Cancer By Regulation Of The Erk/Mapk–Cyclin D1/Cdk4 Pathway, S Wang, X Wang, Y Gao, Y Peng, Et Al

Peninsula Medical School

RN181, a RING finger domain-containing protein, is an E3 ubiquitin ligase. However, its biological function and clinical significance in cancer biology are obscure. Here, we report that RN181 expression is significantly down-regulated in 165 tumour tissues of gastric carcinoma (GC) versus adjacent non-tumour tissues, and inversely associated with tumour differentiation, tumour size, clinical stage, and patient's overall survival. Alterations of RN181 expression in GC cells by retrovirus-transduced up-regulation and down-regulation demonstrated that RN181 functions as a tumour suppressor to inhibit growth of GC in both in vitro culture and in vivo animal models by decreasing tumour cell proliferation and increasing …

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2019 Undergraduate Research Symposium: Full Program, Honors College, Old Dominion University Feb 2019

2019 Undergraduate Research Symposium: Full Program, Honors College, Old Dominion University

Undergraduate Research Symposium

Full program with schedule and abstracts for the 2019 Undergraduate Research Symposium.

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Biological Biomedical Seminar | You Are What You Don't Eat Bacterial Adaptation To Host Imposed Nutrient Starvation, March 18, Ohio University College Of Arts & Sciences Feb 2019

Biological Biomedical Seminar | You Are What You Don't Eat Bacterial Adaptation To Host Imposed Nutrient Starvation, March 18, Ohio University College Of Arts & Sciences

All Forum Articles

No abstract provided.

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Plant Biology Colloquium | Lasting Contributions Of Pasture Trees, Feb 22, Ohio University College Of Arts & Sciences Feb 2019

Plant Biology Colloquium | Lasting Contributions Of Pasture Trees, Feb 22, Ohio University College Of Arts & Sciences

All Forum Articles

No abstract provided.

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What Did We Learn About Vads In 2018?, Maya Guglin Feb 2019

What Did We Learn About Vads In 2018?, Maya Guglin

The VAD Journal

No abstract provided.

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Minutes, College Of Arts & Sciences Department Chairs Meeting, February 12, 2019, Bridget Nickens Feb 2019

Minutes, College Of Arts & Sciences Department Chairs Meeting, February 12, 2019, Bridget Nickens

Department Chairs Meetings

Minutes from the February 12, 2019, meeting of the department chairs from the University of South Florida St. Petersburg's College of Arts and Sciences.

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An Economic Feasibility Assessment Of Autonomous Field Machinery In Grain Crop Production, Jordan Murphy Shockley, Carl R. Dillon, Scott A. Shearer Feb 2019

An Economic Feasibility Assessment Of Autonomous Field Machinery In Grain Crop Production, Jordan Murphy Shockley, Carl R. Dillon, Scott A. Shearer

Agricultural Economics Faculty Publications

A multi-faceted whole farm planning model is developed to compare conventional and autonomous machinery for grain crop production under various benefit, farm size, suitable field day risk aversion, and grain price scenarios. Results suggest that autonomous machinery can be an economically viable alternative to conventional manned machinery if the establishment of intelligent controls is cost effective. An increase in net returns of 24% over operating with conventional machinery is found when including both input savings and a yield increase due to reduced compaction. This study also identifies the break-even investment price for intelligent controls for the safe and reliable commercialization …

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Carbon Dioxide (Co2) And Methane (Ch4) Fluxes From Agricultural Drainage Canals At The Timberlake Observatory For Wetland Restoration In North Carolina’S Coastal Plain, Hannah V. Schleupner, Katherine L. Juarez, Mary J. Carmichael Feb 2019

Carbon Dioxide (Co2) And Methane (Ch4) Fluxes From Agricultural Drainage Canals At The Timberlake Observatory For Wetland Restoration In North Carolina’S Coastal Plain, Hannah V. Schleupner, Katherine L. Juarez, Mary J. Carmichael

RURALS: Review of Undergraduate Research in Agricultural and Life Sciences

Wetlands play an integral role in the global biogeochemical cycling of carbon (C). Historically, research on carbon dynamics in wetlands has focused on large-scale wetlands that are easily recognized on the landscape. However, cryptic wetlands- wetlands that may be small-scale, seasonally inundated, and/or otherwise difficult to identify or characterize on a landscape- occur throughout the Earth’s surface. Agricultural drainage canals represent one type of cryptic wetland environment. Even though they are individually small, the collective imprint of drainage canals across a landscape, especially in low-lying regions where land use is dominated by agriculture, may be large. Herein, we measure CO …

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Poetry Across The Curriculum: New Methods Of Writing Intensive Pedagogy For U.S. Community College And Undergraduate Education: A Book Review, Rama Cousik Feb 2019

Poetry Across The Curriculum: New Methods Of Writing Intensive Pedagogy For U.S. Community College And Undergraduate Education: A Book Review, Rama Cousik

The Qualitative Report

This book review presents the basic premise of the book, which is use of poetry to teach undergraduate courses. The author of the review shares her own experiences with using poetry to teach college courses and highlights the beginning chapters. The editors of the book, Frank Jacobs, Shannon Kincaid and Amy. E. Traver, and other authors share their experiences from a workshop on the use of poetry in college. Empirical and anecdotal examples do well to underscore the need for more arts-based education and particularly poetry in teaching college courses.

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Second Chances In The Wire: Perspectives From Psychology And The Judiciary, Rebecca R. Pallmeyer, Dan P. Mcadams Feb 2019

Second Chances In The Wire: Perspectives From Psychology And The Judiciary, Rebecca R. Pallmeyer, Dan P. Mcadams

University of Chicago Legal Forum

Playing off a scene in The Wire wherein prison inmates discuss whether American lives have “second acts,” this essay considers psychological and legal issues at play in people’s efforts to turn their lives around, from bad to good. In the first half of the essay, a professor of psychology discusses empirical research into redemptive life stories in which people find positive meaning in suffering and/or transform their lives from failure to relative success. While examples of redemptive life stories may be found in The Wire, making good on second chances seems to be a relatively rare occurrence. In the second …

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Invasion Genetics Of The Mummichog (Fundulus Heteroclitus): Recent Anthropogenic Introduction In Iberia, Teofilo Morim, Grant R. Bigg, Pedro M. Madeira, Jorge Palma, David D. Duvernell, Enric Gisbert, Regina L. Cunha, Rita Castilho Feb 2019

Invasion Genetics Of The Mummichog (Fundulus Heteroclitus): Recent Anthropogenic Introduction In Iberia, Teofilo Morim, Grant R. Bigg, Pedro M. Madeira, Jorge Palma, David D. Duvernell, Enric Gisbert, Regina L. Cunha, Rita Castilho

Biological Sciences Faculty Research & Creative Works

Human activities such as trade and transport have increased considerably in the last decades, greatly facilitating the introduction and spread of non-native species at a global level. In the Iberian Peninsula, Fundulus heteroclitus, a small euryhaline coastal fish with short dispersal, was found for the first time in the mid-1970s. Since then, F. heteroclitus has undergone range expansions, colonizing the southern region of Portugal, southwestern coast of Spain and the Ebro Delta in the Mediterranean Sea. Cytochrome b sequences were used to elucidate the species invasion pathway in Iberia. Three Iberian locations (Faro, Cádiz and Ebro Delta) and 13 …

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Does The Acorn Barnacle Balanus Glandula Exhibit Predictable Gradients In Metabolic Performance Across The Intertidal Zone?, Kali Horn Feb 2019

Does The Acorn Barnacle Balanus Glandula Exhibit Predictable Gradients In Metabolic Performance Across The Intertidal Zone?, Kali Horn

Baker/Koob Endowments Awarded Projects

Intertidal organisms live in one of the most environmentally stressful habitats on the planet, and daily fluctuations they experience in abiotic factors (e.g., temperature, oxygen, salinity, pH) are predicted to intensify as our global climate continues to change. Elevated temperature and oxygen limitation are two dominant stressors associated with periodic air emersion in the littoral zone; both of which have substantial direct effects on metabolism in ectotherms. In the proposed study, we aim to profile the ‘metabolic phenotype’ of acorn barnacles (Balanus glandula) from different intertidal zones (low, mid, high). We define metabolic phenotype as the individual’s baseline metabolic performance, …

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Faculty Senate Minutes - February 1, 2019, Usm Faculty Senate Feb 2019

Faculty Senate Minutes - February 1, 2019, Usm Faculty Senate

Faculty Senate Minutes

No abstract provided.

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