Open Access. Powered by Scholars. Published by Universities.®

Digital Commons Network™

Open Access. Powered by Scholars. Published by Universities.®

2019

Discipline
Institution
Keyword
Publication
Publication Type
File Type

Articles 8941 - 8970 of 9649

Full-Text Articles in Entire DC Network

Development Of The Adept Screening Tool To Identify Health And Fitness Apps That Pose Risk For Individuals Susceptible To Disordered Eating, Georgia Mcartney Jan 2019

Development Of The Adept Screening Tool To Identify Health And Fitness Apps That Pose Risk For Individuals Susceptible To Disordered Eating, Georgia Mcartney

Graduate Research Theses & Dissertations

Popular health apps could contain risk factors for disordered eating such as restriction, weight stigma, harmful exercise, or compensation. Although previous studies have examined the connection between social media and disordered eating, data is lacking regarding risk factors from health apps. The purpose of this study is to develop a rating tool to detect, examine, and categorize app-based risk factors for disordered eating.

This study utilized a comprehensive review of literature regarding risk factors for disordered eating, connections between app use and disordered eating behaviors, and existing technology rating tools. Based on this framework, the Awareness of Disordered Eating

Promotion …


Codon-Specific Translation By M1g37 Methylation Of Trna, Ya-Ming Hou, Isao Masuda, Howard Gamper Jan 2019

Codon-Specific Translation By M1g37 Methylation Of Trna, Ya-Ming Hou, Isao Masuda, Howard Gamper

Department of Biochemistry and Molecular Biology Faculty Papers

Although the genetic code is degenerate, synonymous codons for the same amino acid are not translated equally. Codon-specific translation is important for controlling gene expression and determining the proteome of a cell. At the molecular level, codon-specific translation is regulated by post-transcriptional epigenetic modifications of tRNA primarily at the wobble position 34 and at position 37 on the 3′-side of the anticodon. Modifications at these positions determine the quality of codon-anticodon pairing and the speed of translation on the ribosome. Different modifications operate in distinct mechanisms of codon-specific translation, generating a diversity of regulation that is previously unanticipated. Here we …


The Risk For Developing Eating Disorders Among Indivdiuals With Diabetes, Nicole Havlik Jan 2019

The Risk For Developing Eating Disorders Among Indivdiuals With Diabetes, Nicole Havlik

Graduate Research Theses & Dissertations

Objective: The objective and purpose of this research was to determine if individuals with type 1 and type 2 diabetes are at risk for developing eating disorders. Currently, there is a gap in literature on the topic of eating disorders and diabetes. Further, there is little research on those with type 2 diabetes and their risk for eating disorder development. Management of diabetes and eating disorder treatment contradict each other. Therefore, there is a need to understand the risk involved in the treatment of diabetes in order to prevent eating disorder development.

Methods: The current study used a Likert-type scale …


Agronomic And Quality Response Of Hard Red Spring Wheat Genotypes To Management Systems In South Dakota, Jonathan Kleinjan Jan 2019

Agronomic And Quality Response Of Hard Red Spring Wheat Genotypes To Management Systems In South Dakota, Jonathan Kleinjan

Electronic Theses and Dissertations

Intensive cereals management techniques such as multiple fungicide applications and in-season split N applications have been used to successfully improve wheat yields in Europe and in some winter wheat production areas of the USA. However, research on the effects of these management practices and their interaction with genotypes is limited in the hard red spring wheat (HRSW) production areas of the USA. The objectives of this study were to: (i) compare management treatments and (ii) quantify any interaction effects between management and genotype on the agronomic characteristics and relevant flour and dough properties of locally-adapted HRSW genotypes. A randomized complete …


Impact Of Concussion And Orthopedic Injuries On Physical Activity And Quality Of Life After Sport Retirement, Makenna Hancock Jan 2019

Impact Of Concussion And Orthopedic Injuries On Physical Activity And Quality Of Life After Sport Retirement, Makenna Hancock

Electronic Theses and Dissertations

CONTEXT: Concussions and orthopedic injuries represent a significant risk related to participation in collegiate athletics. These injuries can create significant long-term impairments and functional limitations which may also decrease former athletes’ quality of life (QoL) and inhibit their ability to engage in physical activity. OBJECTIVE: To investigate QoL and physical activity levels of former collegiate athletes with a history of concussion and orthopedic injury, orthopedic injury only, and healthy controls. DESIGN: Descriptive, experimental study.
SETTING: Daily life as former National Collegiate Athletic Association Division I collegiate athlete.
PARTICIPANTS: Former Division I collegiate athletes competing in football, women’s soccer, baseball, softball, …


Production And Storage Stability Of High Concentrated Micellar Casein And Its Effect On The Functional Properties Of Process Cheese Products, Ahmed Hammam Jan 2019

Production And Storage Stability Of High Concentrated Micellar Casein And Its Effect On The Functional Properties Of Process Cheese Products, Ahmed Hammam

Electronic Theses and Dissertations

Micellar casein is a high-protein ingredient that can be used in process cheese products (PCP) formulations. PCP is a dairy food prepared by blending dairy ingredients (such as natural cheese, protein concentrates, butter, non-fat dry milk NFDM, whey powder, and permeate) with nondairy ingredients (such as sodium chloride, water, emulsifying salts, color, and flavors) and then heating the mixture with a continuous agitation to produce a homogeneous product with an extended shelf-life. The first objective of this study was to produce a highly concentrated micellar casein (HC-MC) and evaluate its storage stability. Skim milk was pasteurized at 76°C for 16 …


Supporting High Quality Early Childhood Experiences For Children With And Without Disabilities And Their Families In Nevada, Jenna Weglarz-Ward, Cyndy Ang, Robin Gaynes Jan 2019

Supporting High Quality Early Childhood Experiences For Children With And Without Disabilities And Their Families In Nevada, Jenna Weglarz-Ward, Cyndy Ang, Robin Gaynes

Policy Issues in Nevada Education: Policy Papers

It has become common for young children to be enrolled in some form early care or education programs before entering kindergarten (Whitebrook, McLean, & Austin, 2016). These experiences can encompass a range of programs and many families use multiple programs to meet their needs (U.S. Census Bureau, 2013). According to the U.S. Departments of Health and Human Services and Education (DHHS/DOE; 2014) early care and education includes programs that: provide early care and education to children birth through age five, where the majority of children in the program are typically developing. These include, but are not limited to, private or …


Whiley V. Scott: Misinterpreting Florida's Historical Scope Of Constitutional Executive Power, Eric Miller Jan 2019

Whiley V. Scott: Misinterpreting Florida's Historical Scope Of Constitutional Executive Power, Eric Miller

Seton Hall Journal of Legislation and Public Policy

No abstract provided.


The Health Care Systems Of The United States And Spain: A Comparison, Tasia Harman Jan 2019

The Health Care Systems Of The United States And Spain: A Comparison, Tasia Harman

Senior Honors Theses

When it comes to understanding and improving the United States health care system, comparison and analysis with the health care system of another country provides valuable insights. In this thesis, the United States’ health care system was compared to that of Spain, as the health care system of Spain is generally ranked well above the United States in terms of quality, function, and cost. In the comparison, information such as the health of the population, the quality of health care received, accessibility, and health care costs indicate the state of the health care systems and their ability to function well …


Evaluation Of The Correlation Between Quantitative Measurement Of The Foveal Avascular Zone And Retinal Vessel Density And Outer Retinal Disruptions In Diabetic Patients, Nagi̇han Uğurlu, Ayşe Güzi̇n Taşlipinar Uzel, Ahmet Şengün, Fatma Yülek, Demet Özdaş, Abbas Ali̇ Tam, Reyhan Ersoy, Beki̇r Çakir Jan 2019

Evaluation Of The Correlation Between Quantitative Measurement Of The Foveal Avascular Zone And Retinal Vessel Density And Outer Retinal Disruptions In Diabetic Patients, Nagi̇han Uğurlu, Ayşe Güzi̇n Taşlipinar Uzel, Ahmet Şengün, Fatma Yülek, Demet Özdaş, Abbas Ali̇ Tam, Reyhan Ersoy, Beki̇r Çakir

Turkish Journal of Medical Sciences

Background/aim: The aim of the current study was to evaluate the correlation between the integrity of the outer retinal layers on optical coherence tomography (OCT) and objective parameters of retinal microvascular perfusion on optical coherence tomography angiography (OCTA).Materials and methods: A total of 105 eyes of 54 diabetic patients were included in the study. Integrity of the outer retinal layers including the external limiting membrane (ELM), ellipsoid zone (EZ), and interdigitation zone (IZ) was assessed by spectral-domain optical coherence tomography. The foveal avascular zone (FAZ) area and vessel density (VD) measurements in the superficial capillary plexus (SCP) and deep capillary …


Assay Development For The Identification Of Species And Bioactive Compounds Of Morinda Citrifolia (Noni) In Dietary Supplements By Rt-Qpcr, Dna Sanger Sequencing And Spectroscopy (Uv-Vis/Ftir), Ricardo L. Fernandez Walker Jan 2019

Assay Development For The Identification Of Species And Bioactive Compounds Of Morinda Citrifolia (Noni) In Dietary Supplements By Rt-Qpcr, Dna Sanger Sequencing And Spectroscopy (Uv-Vis/Ftir), Ricardo L. Fernandez Walker

Master's Theses

Regulation standards for dietary supplements lack greatly. Due to this, fraud during the manufacturing of these products might be committed. Previous investigations on herbal dietary supplements have shown that the main ingredient was not present in most of the herbal supplements tested and that these products also contained other substances not stated in the label The purpose of this study was to develop a fluorescent qPCR assay for the identification of Morinda citrifolia herbal species in dietary supplements. Primers for genetic regions rbcL and matK of M. citrifolia were designed. The potential of novel matK primer showed discrimination potential …


Disruption Of Immune Homeostasis In Human Dendritic Cells Via Regulation Of Autophagy And Apoptosis By Porphyromonas Gingivalis, Mohamed M Meghil, Omnia K Tawfik, Mahmoud Elashiry, Mythilypriya Rajendran, Roger M Arce, David J Fulton, Patricia V Schoenlein, Christopher W Cutler Jan 2019

Disruption Of Immune Homeostasis In Human Dendritic Cells Via Regulation Of Autophagy And Apoptosis By Porphyromonas Gingivalis, Mohamed M Meghil, Omnia K Tawfik, Mahmoud Elashiry, Mythilypriya Rajendran, Roger M Arce, David J Fulton, Patricia V Schoenlein, Christopher W Cutler

Faculty, Staff and Student Publications

As fundamental processes of immune homeostasis, autophagy, and apoptosis must be maintained to mitigate risk of chronic inflammation and autoimmune diseases. Periodontitis is a chronic inflammatory disease characterized by oral microbial dysbiosis, and dysregulation of dendritic cell (DC) and T cell responses. The aim of this study was to elucidate the underlying mechanisms by which the oral microbe


From The Laboratory To The Vineyard—Evolution Of The Measurement Of Grape Composition Using Nir Spectroscopy Towards High-Throughput Analysis, Aoife Power, Vi Khanh Truong, James Chapman, Daniel Cozzolino Jan 2019

From The Laboratory To The Vineyard—Evolution Of The Measurement Of Grape Composition Using Nir Spectroscopy Towards High-Throughput Analysis, Aoife Power, Vi Khanh Truong, James Chapman, Daniel Cozzolino

Articles

Compared to traditional laboratory methods, spectroscopic techniques (e.g., near infrared, hyperspectralimaging)provideanalystswithaninnovativeandimprovedunderstandingofcomplex issuesbydeterminingseveralchemicalcompoundsandmetabolitesatonce,allowingforthecollection of the sample “fingerprint”. These techniques have the potential to deliver high-throughput options for the analysis of the chemical composition of grapes in the laboratory, the vineyard and before or during harvest, to provide better insights of the chemistry, nutrition and physiology of grapes. Faster computers, the development of software and portable easy to use spectrophotometers and data analytical methods allow for the development of innovative applications of these techniques for the analyses of grape composition.


A Bioinfomatic Analysis Of Luminal And Mucosal Ileal Bacteria Colonizing Nursery Pigs Fed Different Protein Sources, Jamie L. Ortman Jan 2019

A Bioinfomatic Analysis Of Luminal And Mucosal Ileal Bacteria Colonizing Nursery Pigs Fed Different Protein Sources, Jamie L. Ortman

Electronic Theses and Dissertations

Weaning is a critical time in a young pig’s life that will greatly impact its adult growth and development. The objective of this research was to evaluate the effects of various protein sources on the bacterial composition within luminal and mucosal populations in simple and complex diets to gain a better understanding of factors influencing gut health. Weaned pigs were fed 1 of 3 simple experimental diets: 1) basic diet containing corn and soybean meal (Negative Control - NEG), 2) basic diet + fishmeal (FM; Positive Control - POS), and 3) basic diet + microbially-enhanced soybean meal (MSBM). Phase I …


Does Medicaid Increase Emergency Room Use: Evidence From Oregon Health Program?, Md Fourkan Jan 2019

Does Medicaid Increase Emergency Room Use: Evidence From Oregon Health Program?, Md Fourkan

Electronic Theses and Dissertations

This thesis paper strives to identify the relationship between Medicaid expansion and Emergency Department use. I use a Monte Carlo simulation for demonstrating the endogeneity problem and a copula model using the Oregon Health Program (OHP) data to show the previous literature has exaggerated the causal relation between Medicaid expansion and Emergency Department use. This paper can be divided into two parts. First, it tries to focus on the under-identification of multiple endogenous variables problem in typical econometrics papers, where researchers correct for a single endogenous variable but intentionally or unintentionally ignore the endogeneity of one or more other independent …


Television Viewing And Markers Of Physical Fitness And Body Composition In College-Aged Students, James Peterson Jan 2019

Television Viewing And Markers Of Physical Fitness And Body Composition In College-Aged Students, James Peterson

Graduate Research Theses & Dissertations

Television viewing is one of the most popular sedentary activities in America. Sedentary behavior has been linked to increased risk of obesity, hypertension, cardiovascular disease, and all-cause mortalities. While many studies have focused on associations in children and middle aged to older adults, there is a dearth of literature regarding young college aged students. PURPOSE: The purpose of this study was to examine the association between daily television screen time viewing and markers of physical fitness and body composition in young college aged students. METHODS: The sample population consisted of 141 Northern Illinois University young college aged students. Subjects completed …


Early Childhood Teacher Educators Perception Of Their Own Critical Reflection On Race, Ethnicity, And Culture, Nicole Denise Porter Jan 2019

Early Childhood Teacher Educators Perception Of Their Own Critical Reflection On Race, Ethnicity, And Culture, Nicole Denise Porter

University of the Pacific Theses and Dissertations

This study examined three tenured early childhood teacher educators from Northern California community colleges on how they valued critical reflection on race, ethnicity, and culture. A narrative inquiry study was conducted to gather information based on in-depth conversational interviews. A timeline identified key experiences, both personal and professional, as well as educational experiences from elementary through high school, undergraduate, graduate, and post-graduate if applicable. The data was collected from the conversational interviews and then analyzed using the transformative learning theory by Mezirow (1991) in identifying key themes. The findings yielded three themes (a) exploring race, ethnicity, and culture, (b) understanding …


The Course Changes In Maximal Strength Velocity Following A Traditional Strength- Or Power Orientated Training Session, Alexander Vernon Jan 2019

The Course Changes In Maximal Strength Velocity Following A Traditional Strength- Or Power Orientated Training Session, Alexander Vernon

Theses

The primary aim of this study was to investigate the return to baseline of movement velocity and maximal strength following a typical strength-orientated and power-orientated session in the full depth, free-weight back squat performed with maximal concentric velocity. Fourteen strength-trained males completed a power-orientated session (3-sets of 6-repetitions @50% of a one-repetition maximum [1RM]) and a strength-orientated session (5-sets of 5-repetitions @80%1RM) in randomised order over two weeks. At 24, 48, 72 and 96-hours following the training session stimulus, sessions were completed with loads of 20%, 40%, 60%, 80%, 90% and 100%1RM lifted. Prior to the completion of the training …


Natural Product Induction In Pencillium And Human Caspase Crystallography, Kelly J. Mcgrath Jan 2019

Natural Product Induction In Pencillium And Human Caspase Crystallography, Kelly J. Mcgrath

Graduate Student Theses, Dissertations, & Professional Papers

No abstract provided.


Predictors Of Resilience Among Infants At Risk For Rapid Weight Gain, Alison K. Ventura, Kristen Thompson Jan 2019

Predictors Of Resilience Among Infants At Risk For Rapid Weight Gain, Alison K. Ventura, Kristen Thompson

Kinesiology and Public Health

Objective: The study objective was to investigate factors associated with resilience to rapid weight gain (RWG) among predominantly bottle-fed infants.

Methods: Data came from 1,353 mothers who participated in the Infant Feeding Practices Study 2. Mothers completed a prenatal questionnaire and monthly surveys of infant feeding and growth between birth and 12 months. Infants were classified as resilient if they were predominantly bottle fed but did not exhibit RWG between birth and the latter half of infancy (≥ +0.67 change in weight-for-age z score).

Results: Thirty-five percent of the sample (n = 467) was predominantly bottle fed but did …


Identification Of Surrogate Biomarkers For The Prediction Of Patients At Risk Of Low Macular Pigment In Type 2 Diabetes, Grainne Scanlon, Daniel Mccartney, John Butler, Ekaterina Loskutova, James Loughman Jan 2019

Identification Of Surrogate Biomarkers For The Prediction Of Patients At Risk Of Low Macular Pigment In Type 2 Diabetes, Grainne Scanlon, Daniel Mccartney, John Butler, Ekaterina Loskutova, James Loughman

Articles

Purpose: This cross-sectional study compared macular pigment (MP) levels among persons with Type 2 diabetes relative to healthy controls. Additionally, a range of behavioral, anthropometric, clinical and serum measures were explored as possible predictors of low MP optical density (MPOD) in diabetes.


Lutein And Zeaxanthin: The Possible Contribution, Mechanisms Of Action And Implications Of Modern Dietary Intake For Cognitive Development In Children. [Version 1; Peer Review: 2 Approved], Ekaterina Loskutova, Kajal Shah, Daniel Ian Flitcroft, Annalisa Setti, John Butler, Yvonne Nolan, Nabin Paudel, James Loughman Jan 2019

Lutein And Zeaxanthin: The Possible Contribution, Mechanisms Of Action And Implications Of Modern Dietary Intake For Cognitive Development In Children. [Version 1; Peer Review: 2 Approved], Ekaterina Loskutova, Kajal Shah, Daniel Ian Flitcroft, Annalisa Setti, John Butler, Yvonne Nolan, Nabin Paudel, James Loughman

Articles

No abstract provided.


2017 Drug Laws In West Virginia: The Wrong Prescription For The State's Opioid Crisis, Wesley A. Shumway Jan 2019

2017 Drug Laws In West Virginia: The Wrong Prescription For The State's Opioid Crisis, Wesley A. Shumway

Penn State Law Review (2003 - Present)

The United States has been devastated by an opioid epidemic. The 1990s, with shifting views of pain management and aggressive marketing of OxyContin, saw the beginning of a crisis that has taken the country by storm. Pain medication prescription rates skyrocketed throughout the United States, and as a result, addiction, overdose, and death have tormented the country in astonishing numbers. However, no state has suffered more than West Virginia. The Mountain State, with its struggling economy, labor-related injuries, and poor educational outcomes, is ground zero for such a crisis. West Virginia has struggled with high addiction and overdose rates. In …


Biopsychosocial Correlates Of Pain In Youth With Eosinophilic Esophagitis: A Comparison To Other Pediatric Patients, Mary Kenna Lynch Jan 2019

Biopsychosocial Correlates Of Pain In Youth With Eosinophilic Esophagitis: A Comparison To Other Pediatric Patients, Mary Kenna Lynch

All ETDs from UAB

EoE is a chronic, clinico-pathological, esophageal disease with symptoms that include dysphagia, reflux, vomiting, feeding aversion, and epigastric pain. Diagnosis requires clinical symptom presentation and histologic findings of eosinophil-predominant inflammation of the esophagus. While the pediatric patient’s epigastric pain is predictive of their quality of life, little is known about their pain experience. Through two studies, the pain experience, sleep quality, and internalizing symptoms of youth with Eosinophilic Esophagitis (EoE) have been examined. Through individually evaluating each of these factors as well as testing their relations with each other, the model proposed by Lynch and colleagues (2015) to understand the …


Occupational Therapy Students’ Perceptions Of Individuals With Mental Illness Before And After A Service-Learning Experience, Valley Mccurry Jan 2019

Occupational Therapy Students’ Perceptions Of Individuals With Mental Illness Before And After A Service-Learning Experience, Valley Mccurry

All ETDs from UAB

Service-learning is a pedagogical approach that allows occupational therapy students to engage in experiential learning with individuals who have mental illness. Perceptions of individuals with mental illness are influenced by factors such as societal stigma. Stigma is present among allied health professionals and students, including occupational therapy students, which may influence provision of care. In order to assess occupational therapy students’ level of comfort with the mental health population, this study used a convergent mixed methods approach to evaluate how students’ personal beliefs and self-efficacy changed after a service-learning experience at a homeless shelter. The study explored occupational therapy students’ …


The Role Of The Built Environment In Transforming Underserved Neighborhoods Into Smart And Connected Communities, Mary Claire Nabors Jan 2019

The Role Of The Built Environment In Transforming Underserved Neighborhoods Into Smart And Connected Communities, Mary Claire Nabors

All ETDs from UAB

The goal of this report is to create a model for transforming underserved neighborhoods into smart, connected, healthy, and sustainable communities by focusing on the built environment. To do this, there must be a thorough neighborhood analysis of the existing conditions with recommendations for what needs to be done, both short term and long term. The built environment impacts many aspects of a neighborhood and the quality of life for residents. Sidewalks, streets, lighting, landscaping, and accessibility are all components of the built environment and research has continuously shown how the deterioration of the built environment affects the health and …


Increasing Low-Income Residents’ Access To Fresh Produce Through A Local Mobile Pantry, Laura E. Wasson, L. Lanier Nalley, Mechelle Bailey, Laura Hill Jan 2019

Increasing Low-Income Residents’ Access To Fresh Produce Through A Local Mobile Pantry, Laura E. Wasson, L. Lanier Nalley, Mechelle Bailey, Laura Hill

Discovery, The Student Journal of Dale Bumpers College of Agricultural, Food and Life Sciences

Seeds that Feed (STF) is a mobile food pantry located in Fayetteville, Arkansas. STF receives produce from local farmers to distribute to residents in low-income housing sites throughout Northwest Arkansas. According to Feeding America, food insecurity affected 14.3% Washington County, Arkansas’ population in 2016. The purpose of this study was to determine if STF’s model is an effective way to increase individuals’ access to fresh fruits and vegetables and increase their potential to meet the United States Department of Agriculture’s Food Patterns (USDA-FP) for to fruit and vegetable consumption. Twenty-three participants from three sites completed the study. A survey was …


Creative Lesson Planning With College And Career Readiness Standards: Thoughts From The Curriculum Library, Margaret Robillard Jan 2019

Creative Lesson Planning With College And Career Readiness Standards: Thoughts From The Curriculum Library, Margaret Robillard

Journal of Excellence in College Teaching and Learning

Preservice teachers carefully craft lesson plans to meet the academic needs of elementary through high school students in their fieldwork. They rely in part on finding high quality texts and trade books that relate to College and Career Readiness Standards (CCR). While college curriculum libraries are excellent sources for materials, their organization often is not aligned with national curriculum academic standards. Preservice teachers therefore sometimes struggle to find appropriate analog resources to create lesson plans that integrate disciplinary literacy. This research utilizes CCR standards, survey data from stakeholders, and library organizational research literature to create a categorization system based on …


Effects Of A Ketogenic Diet On Body Composition, Metabolic Health, And Quality Of Life In Ovarian And Endometrial Cancer Patients, Caroline Whitney Cohen Jan 2019

Effects Of A Ketogenic Diet On Body Composition, Metabolic Health, And Quality Of Life In Ovarian And Endometrial Cancer Patients, Caroline Whitney Cohen

All ETDs from UAB

Ketogenic diets (KDs) have garnered considerable research attention in recent years, having been investigated as a therapy for neurologic, metabolic, and even dermatologic diseases. Recent research has also focused on KDs as a potential intervention for cancer, with preclinical studies demonstrating profound effects such as inhibiting tumor growth, enhancing the effects of radiation and chemotherapy, and prolonging survival. However, to date few studies have been conducted in cancer patients. In order to determine if KDs might augment existing cancer treatment protocols, additional research is needed. Accordingly, the objective of this project was to conduct the first randomized, controlled trial examining …


Examining The Role Of The Unfolded Protein Response In Depression, Matthew Timberlake Jan 2019

Examining The Role Of The Unfolded Protein Response In Depression, Matthew Timberlake

All ETDs from UAB

Depression is the leading cause of disability worldwide and impacts nearly 350 million people with a disproportionate representation in women with a 1:1.7 ratio of occurrence compared to men. This disorder is characterized by shifts in mood to include feelings of hopelessness, sadness, and lethargy as well as changes in diet, motivation, and sleep patterns. Further, over 50% of patients who struggle with depression also have suicidal ideation and as many as 10% of those commit suicide. At present, treatment plans include behavioral therapy (often) in conjunction with antidepressant medications which act on monoamines and their circuits in the central …