Open Access. Powered by Scholars. Published by Universities.®

Digital Commons Network™

Open Access. Powered by Scholars. Published by Universities.®

2019

Discipline
Institution
Keyword
Publication
Publication Type
File Type

Articles 8761 - 8790 of 9649

Full-Text Articles in Entire DC Network

Patient Involvement In Healthcare Projects: A Mixed Method Study On The Perspectives Of Project Staff In Western Australian (Wa) Public Hospitals And Health Services, Melanie Wright Jan 2019

Patient Involvement In Healthcare Projects: A Mixed Method Study On The Perspectives Of Project Staff In Western Australian (Wa) Public Hospitals And Health Services, Melanie Wright

Theses

Background: the benefits of patient involvement in clinical care and research is well described in the literature; but there is little evidence to suggest that involving patients in the planning and delivery of healthcare projects is beneficial to the outcomes of the project.

Purpose: this study explores the perspectives of staff who were specifically employed to lead and manage healthcare projects in Western Australian (WA) public hospitals and health services, regarding patient involvement in their projects and the perceived benefits and barriers of this involvement.

Study design: the study was designed using a sequential mixed method approach in three phases …


Strafford County 2018 Annual Report Of The Commissioners, Treasurer, Other County Officers And The Strafford County Delegation Strafford County, New Hampshire For The Year Ending December 31, 2018., Stafford County Representatives Jan 2019

Strafford County 2018 Annual Report Of The Commissioners, Treasurer, Other County Officers And The Strafford County Delegation Strafford County, New Hampshire For The Year Ending December 31, 2018., Stafford County Representatives

Strafford County, NH Annual Reports

This is an annual report containing vital statistics for a county in the state of New Hampshire.


Sibling Sex, But Not Androgens, Shapes Phenotypes In Perinatal Common Marmosets (Callithrix Jacchus), Brett M. Frye, Lisa G. Rapaport, Michael W. Sears, Talia Melber, Suzette D. Tardif Jan 2019

Sibling Sex, But Not Androgens, Shapes Phenotypes In Perinatal Common Marmosets (Callithrix Jacchus), Brett M. Frye, Lisa G. Rapaport, Michael W. Sears, Talia Melber, Suzette D. Tardif

Publications

When offspring share a womb, interactions among fetuses can impart lasting impressions on phenotypic outcomes. Such intrauterine interactions often are mediated by sex steroids (estrogens and androgens) produced by the developing fetuses. In many mammals, intrauterine interactions between brothers and sisters lead to masculinization of females, which can induce fitness consequences. Many litter-bearing primates, though, seem to escape androgen-mediated litter effects, begging why? Here, we investigated how the sex composition (i.e., same- or mixed-sex) of litters influences perinatal outcomes in the common marmoset monkey (Callithrix jacchus), using a combination of physiological, morphological, and behavioural assays. We hypothesized that …


Global Health Elective In Rural Guatemala, Kendall Burns Jan 2019

Global Health Elective In Rural Guatemala, Kendall Burns

Posters

Describes pediatric resident's experience learning to translate evidence based medicine to resource-limited areas in rural Guatemala.


Impact Investment Strategy: Linking Health & Housing, Elizabeth G. Mckinsey Jan 2019

Impact Investment Strategy: Linking Health & Housing, Elizabeth G. Mckinsey

Master of Urban and Regional Planning Capstone Projects

The purpose of this plan is to create an impact investment strategy for RMHF that explicitly links health and housing. The strategy will use impact investing, an investment strategy that directs capital to enterprises that generate social and or environmental benefits for the surrounding community. One of RMHF’s goals is for the investment strategy to offer strategies that address the entrenched racism and inequities in the City of Richmond. Impact investing will enable RMHF to be a contributing partner with Richmond as it moves away from a history of unfair housing policies that negatively impact countless citizens to a healthier, …


Metaproteomic Investigation Of The Vaginal Microbiome In Pregnancy, Zaneera Hassan Jan 2019

Metaproteomic Investigation Of The Vaginal Microbiome In Pregnancy, Zaneera Hassan

Theses and Dissertations

The development of early diagnostics and prevention strategies for preterm birth is an important global health challenge with the potential to impact over 15 million children annually, by improving health outcomes and reducing economic burden. Advances in microbial sequencing technology have opened the door to 16S rRNA gene survey, whole metagenomics, and whole transcriptomics, providing molecular evidence that the composition of the vaginal microbiome affects pregnancy outcomes in women, particularly those of African descent. A current gap in our molecular level understanding of the vaginal microbiome as it relates to healthy pregnancies is the metaproteome which comprises proteins from both …


Geographic Proximity To Healthy Food Not Associated With Increased Prevalence Of Cardiovascular Risk Factors In Stroke Patients, Alan D. Howard, Chigozirim Izeogu, Adeniyi J. Idigo, Michael J. Lyerly Jan 2019

Geographic Proximity To Healthy Food Not Associated With Increased Prevalence Of Cardiovascular Risk Factors In Stroke Patients, Alan D. Howard, Chigozirim Izeogu, Adeniyi J. Idigo, Michael J. Lyerly

UAB Huntsville Research Day - All Presentations

2019 research poster


Automatic Nonnutritive Suck Waveform Discrimination And Feature Extraction In Preterm Infants, Chunxiao Liao, Austin O. Rosner, Jill L. Maron, Dongli Song, Steven M. Barlow Jan 2019

Automatic Nonnutritive Suck Waveform Discrimination And Feature Extraction In Preterm Infants, Chunxiao Liao, Austin O. Rosner, Jill L. Maron, Dongli Song, Steven M. Barlow

School of Computing: Faculty Publications

Background and Objective: +e emergence of the nonnutritive suck (NNS) pattern in preterm infants reflects the integrity of the brain and is used by clinicians in the neonatal intensive care unit (NICU) to assess feeding readiness and oromotor development. A critical need exists for an integrated software platform that provides NNS signal preprocessing, adaptive waveform discrimination, feature detection, and batch processing of big data sets across multiple NICU sites. +us, the goal was to develop and describe a crossplatform graphical user interface (GUI) and terminal application known as NeoNNS for single and batch file time series and frequency-domain analyses of …


Infertility Patient-Provider Communication And (Dis)Continuity Of Care: An Exploration Of Illness Identity Transitions, Angela L. Palmer-Wackerly, Heather L Voorhees, Sarah D’Souza, Edward Weeks Jan 2019

Infertility Patient-Provider Communication And (Dis)Continuity Of Care: An Exploration Of Illness Identity Transitions, Angela L. Palmer-Wackerly, Heather L Voorhees, Sarah D’Souza, Edward Weeks

Department of Communication Studies: Faculty Publications

Objective: To identify how and why infertility patients’ communication with health care providers relates to their continuity of care within infertility treatment.

Method: A grounded theory analysis was conducted for 25 in-depth interviews across three coding phases, where we remained open to all themes present in the data, narrowed to most prominent themes, and found the connections between the themes.

Results: Based on our identified themes, we created a conceptual model that explains why infertility patients (dis)continued care with one or more clinician. Through this model, we describe two infertility identity transitions for patients: Transition 1: “Infertility as Temporary” to …


Wheat Streak Mosaic Virus Alters The Transcriptome Of Its Vector, Wheat Curl Mite (Aceria Tosichella Keifer), To Enhance Mite Development And Population Expansion, Adarsh K. Gupta, Erin D. Scully, Nathan A. Palmer, Scott M. Geib, Gautam Sarath, Gary L. Hein, Satyanarayana Tatineni Jan 2019

Wheat Streak Mosaic Virus Alters The Transcriptome Of Its Vector, Wheat Curl Mite (Aceria Tosichella Keifer), To Enhance Mite Development And Population Expansion, Adarsh K. Gupta, Erin D. Scully, Nathan A. Palmer, Scott M. Geib, Gautam Sarath, Gary L. Hein, Satyanarayana Tatineni

Department of Entomology: Faculty Publications

Wheat streak mosaic virus (WSMV; genus Tritimovirus; family Potyviridae) is an economically important wheat virus that is transmitted by the wheat curl mite (WCM; Aceria tosichella Keifer) in a persistent manner. Virus–vector coevolution may potentially influence vector gene expression to prolong viral association and thus increase virus transmission efficiency and spread. To understand the transcriptomic responses of WCM to WSMV, RNA sequencing was performed to assemble and analyse transcriptomes of WSMV viruliferous and aviruliferous mites. Among 7291 de novo-assembled unigenes, 1020 were differentially expressed between viruliferous and aviruliferous WCMs using edgeR at a false discovery rate ≤0.05. …


Effect Of Neem-Based Botanicals And Abamectin 1.8% Ec Against Phyllocnistis Citrella1 In Citrus Reticulata (Rutaceae) Nursery Plantations, Muhammad Arshad, Muhammad Irfan Ullah, Muhammad Afzal, Jaime Molina-Ochoa, Omar Francisco Prado-Rebolledo, John E. Foster Jan 2019

Effect Of Neem-Based Botanicals And Abamectin 1.8% Ec Against Phyllocnistis Citrella1 In Citrus Reticulata (Rutaceae) Nursery Plantations, Muhammad Arshad, Muhammad Irfan Ullah, Muhammad Afzal, Jaime Molina-Ochoa, Omar Francisco Prado-Rebolledo, John E. Foster

Department of Entomology: Faculty Publications

Citrus leafminer, Phyllocnistis citrella Stainton, is an economically important insect pest of citrus in Pakistan, Mexico, the United States and many other citrus-producing countries. Extract of Azadirachta indica A. Juss at 5 and 7% and its oil at 1 and 1.5% concentrations were tested in comparison to synthetic insecticide abamectin 1.8% EC against P. citrella in nursery plantations of Citrus reticulata L. Control of all larval instars of citrus leafminer was good with application of abamectin and A. indica oil during fall 2015 and summer 2016. Abamectin suppressed 75-90% of P. citrella larvae both seasons. A. indica oil at greater …


Temperature Dependent Development Of Sugarcane Aphids Melanaphis Sacchari, (Hemiptera: Aphididae) On Three Different Host Plants With Estimates Of The Lower And Upper Threshold For Fecundity, Michael A. De Souza, J. Scott Armstrong, W. Wyatt Hoback, Phillip G. Mulder, Sulochana Paudyal, John E. Foster, Mark E. Payton, Josephine Akosa Jan 2019

Temperature Dependent Development Of Sugarcane Aphids Melanaphis Sacchari, (Hemiptera: Aphididae) On Three Different Host Plants With Estimates Of The Lower And Upper Threshold For Fecundity, Michael A. De Souza, J. Scott Armstrong, W. Wyatt Hoback, Phillip G. Mulder, Sulochana Paudyal, John E. Foster, Mark E. Payton, Josephine Akosa

Department of Entomology: Faculty Publications

The sugarcane aphid, Melanaphis sacchari (Zehntner) is a serious economic threat to grain sorghum across the U.S. sorghum belt. It can develop on multiple grass hosts but only appears to survive winter temperatures in Texas near the Mexican border, Florida and Louisiana. Because survival and reproduction of aphids is dependent on access to appropriate nutrition and temperatures at which metabolic processes are maintained, we evaluated the growth, reproduction and survival of sugarcane aphids at constant temperatures (5°C,10°C,15°C,20°C,25°C,30°C,35°C) on three known hosts, sorghum, Johnsongrass, and Columbus grass. Longevity, fecundity, number of female nymphs/d, reproductive period in d, and intrinsic rate of …


Chlorothalonil Exposure Alters Virus Susceptibility And Markers Of Immunity, Nutrition, And Development In Honey Bees, Scott T. O'Neal, Alison M. Reeves, Richard D. Fell, Carlyle C. Brewster, Troy D. Anderson Jan 2019

Chlorothalonil Exposure Alters Virus Susceptibility And Markers Of Immunity, Nutrition, And Development In Honey Bees, Scott T. O'Neal, Alison M. Reeves, Richard D. Fell, Carlyle C. Brewster, Troy D. Anderson

Department of Entomology: Faculty Publications

Chlorothalonil is a broad spectrum chloronitrile fungicide that has been identified as one of the most common pesticide contaminants found in managed honey bees (Hymenoptera: Apidae: Apis mellifera L.), their food stores, and the hive environment. While not acutely toxic to honey bees, several studies have identified potential sublethal effects, especially in larvae, but comprehensive information regarding the impact of chlorothalonil on adults is lacking. The goal of this study was to investigate the effects of exposure to a field relevant level of chlorothalonil on honey bee antiviral immunity and biochemical markers of general and social immunity, as well as …


Community Composition, Abundance, And Phenology Of Stink Bugs (Hemiptera: Pentatomidae) In Soybean In The North Central Region Of The United States, Daniela Pezzini, Christina D. Difonzo, Deborah L. Finke, Thomas Hunt, Janet J. Knodel, Christian H. Krupke, Brian P. Mccornack, Andrew P. Michel, Christopher R. Philips, Adam J. Varenhorst, Robert J. Wright, Robert Koch Jan 2019

Community Composition, Abundance, And Phenology Of Stink Bugs (Hemiptera: Pentatomidae) In Soybean In The North Central Region Of The United States, Daniela Pezzini, Christina D. Difonzo, Deborah L. Finke, Thomas Hunt, Janet J. Knodel, Christian H. Krupke, Brian P. Mccornack, Andrew P. Michel, Christopher R. Philips, Adam J. Varenhorst, Robert J. Wright, Robert Koch

Department of Entomology: Faculty Publications

Stink bugs (Hemiptera: Pentatomidae) are an increasing threat to soybean (Fabales: Fabaceae) production in the North Central Region of the United States, which accounts for 80% of the country’s total soybean production. Characterization of the stink bug community is essential for development of management programs for these pests. However, the composition of the stink bug community in the region is not well defined. This study aimed to address this gap with a 2-yr, 9-state survey. Specifically, we characterized the relative abundance, richness, and diversity of taxa in this community, and assessed phenological differences in abundance of herbivorous and predatory stink …


Mycoprotein: The Future Of Nutritious Nonmeat Protein, A Symposium Review, Tim Ja Finnigan, Benjamin T. Wall, Peter J. Wilde, Francis B. Stephens, Steve Taylor, Marjorie R. Freedman Jan 2019

Mycoprotein: The Future Of Nutritious Nonmeat Protein, A Symposium Review, Tim Ja Finnigan, Benjamin T. Wall, Peter J. Wilde, Francis B. Stephens, Steve Taylor, Marjorie R. Freedman

Department of Food Science and Technology: Faculty Publications

Mycoprotein is an alternative, nutritious protein source with a meat-like texture made from Fusarium venenatum, a naturally occurring fungus. Its unique method of production yields a significantly reduced carbon and water footprint relative to beef and chicken. Mycoprotein, sold as Quorn, is consumed in 17 countries, including the United States. In line with current dietary guidelines, mycoprotein is high in protein and fiber, and low in fat, cholesterol, sodium, and sugar. Mycoprotein may help maintain healthy blood cholesterol levels, promote muscle synthesis, control glucose and insulin levels, and increase satiety. It is possible that some susceptible consumers will become sensitized, …


In Vitro Bioaccessibility Of Low-Crystallinity Phytosterol Nanoparticles Generated Using Nanoporous Starch Bioaerogels, Ali Ubeyitogullari, Regis Moreau, Devin J. Rose, Ozan Ciftci Jan 2019

In Vitro Bioaccessibility Of Low-Crystallinity Phytosterol Nanoparticles Generated Using Nanoporous Starch Bioaerogels, Ali Ubeyitogullari, Regis Moreau, Devin J. Rose, Ozan Ciftci

Department of Food Science and Technology: Faculty Publications

Phytosterols are natural health-promoting bioactive compounds; however, phytosterols have very limited bioavailability due to their crystalline lipophilic structure. With the aim of improving bioaccessibility, low-crystallinity phytosterol nanoparticles were generated by supercritical carbon dioxide (SC-CO2) impregnation of phytosterols into nanoporous starch aerogels (NSAs). The in vitro bioaccessibility of the phytosterol nanoparticles (35%) was significantly higher than that of the crude phytosterols (3%) after sequential oral, gastric, and intestinal digestion. The percentages of starch hydrolysis were not different among the various NSA preparations and reached to 64% after sequential digestion. The zeta potential of the phytosterol nanoparticles was higher compared to that …


Formation Of Low-Density And Free-Flowing Hollow Microparticles From Butter And Fractionated Palm Oil Mixture, Joshua Gudeman, Junsi Yang, Ozan Ciftci Jan 2019

Formation Of Low-Density And Free-Flowing Hollow Microparticles From Butter And Fractionated Palm Oil Mixture, Joshua Gudeman, Junsi Yang, Ozan Ciftci

Department of Food Science and Technology: Faculty Publications

The use of solid fats is challenging due to difficulty in incorporating into foods, handling during industrial food production, and relatively high-calorie contributions. The objective of this study was to form free-flowing and low-density hollow microparticles from nonhydrogenated fats, namely, butter and fractionated palm oil, using a novel method based on atomization of a carbon dioxide (CO2)- expanded lipid mixture. The melting point of the fractionated palm oil decreased from 66.2 to 47.3°C above 120 bar in the presence of pressurized CO2. The density of the particles decreased five-folds compared to that of the original oils. …


Extraction Of Astaxanthin From Engineered Camelina Sativa Seed Using Ethanol-Modified Supercritical Carbon Dioxide, Liyang Xie, Edgar B. Cahoon, Yue Zhang, Ozan Ciftci Jan 2019

Extraction Of Astaxanthin From Engineered Camelina Sativa Seed Using Ethanol-Modified Supercritical Carbon Dioxide, Liyang Xie, Edgar B. Cahoon, Yue Zhang, Ozan Ciftci

Department of Food Science and Technology: Faculty Publications

Natural astaxanthin, a high-value carotenoid that is currently extracted mainly from marine organisms, was extracted from engineered camelina seed using ethanol-modified supercritical carbon dioxide (SC-CO2) for the first time, and compared with hexane and accelerated solvent extraction using hexane and ethanol. Response surface methodology (RSM) based on central composite rotatable design was employed to investigate the effect of pressure (30–45 MPa), temperature (40–60 °C), and ethanol concentration (10–35%, w/w). RSM-optimized conditions (41.6 MPa, 36.6 °C and 42.0% ethanol concentration) predicted the astaxanthin concentration as 437 μg/g oil, whereas the actual concentration was 421 ± 14 μg/g oil. Astaxanthin …


Histone Acetylation Increases In Response To Ferulic, Gallic, And Sinapic Acids Acting Synergistically In Vitro To Inhibit Candida Albicans Yeast‐To‐Hyphae Transition, Cristiane R. S. Câmara, Qin-Yin Shi, Matthew Pedersen, Richard Zbasnik, Kenneth Nickerson, Vicki Schlegel Jan 2019

Histone Acetylation Increases In Response To Ferulic, Gallic, And Sinapic Acids Acting Synergistically In Vitro To Inhibit Candida Albicans Yeast‐To‐Hyphae Transition, Cristiane R. S. Câmara, Qin-Yin Shi, Matthew Pedersen, Richard Zbasnik, Kenneth Nickerson, Vicki Schlegel

Department of Food Science and Technology: Faculty Publications

Novel treatments are needed to prevent candidiasis/candidemia infection due to the emergence of Candida species resistant to current antifungals. Considering the yeast-to‐hyphae switch is a critical factor to Candida albicans virulence, phenols common in plant sources have been reported to demonstrating their ability to prevent dimorphism. Therefore, phenols present in many agricultural waste stress (ferulic (FA) and gallic (GA) acid) were initially screened in isolation for their yeast‐to‐hyphae inhibitory properties at times 3, 6, and 24 hr. Both FA and GA inhibited 50% of hyphae formation inhibitory concentration (IC50) but at a concentration of 8.0 ± 0.09 and …


Physicochemical Properties And Rheological Behavior Of Flours And Starches From Four Bean Varieties For Gluten-Free Pasta Formulation, Hollman Motta Romero, Yue Zhang Jan 2019

Physicochemical Properties And Rheological Behavior Of Flours And Starches From Four Bean Varieties For Gluten-Free Pasta Formulation, Hollman Motta Romero, Yue Zhang

Department of Food Science and Technology: Faculty Publications

The rheological behavior of gluten-free flour dispersions from four pulse market classes, including great northern, navy, red kidney (Phaseolus vulgaris L.), and garbanzo beans (Cicer arietinum) were evaluated and compared to soft wheat as a gluten-containing control. Their starches were isolated and the relationships between flour behavior and starch characteristics were studied. Soft wheat (56%) and garbanzo (39%) flours presented higher starch contents than the Phaseolus vulgaris beans (33–35%), which resulted in the development of stronger gel network structures. It was found that starch amylose content and granule size affected the swelling and pasting properties of both starches and flours. …


N-Glycans From Human Milk Glycoproteins Are Selectively Released By An Infant Gut Symbiont In Vivo, Sercan Karav, Giorgio Casaburi, Aysenur Arslan, Merve Kaplan, Berfin Sucu, Steven Frese Jan 2019

N-Glycans From Human Milk Glycoproteins Are Selectively Released By An Infant Gut Symbiont In Vivo, Sercan Karav, Giorgio Casaburi, Aysenur Arslan, Merve Kaplan, Berfin Sucu, Steven Frese

Department of Food Science and Technology: Faculty Publications

Complex, indigestible free oligosaccharides as well as conjugated glycans are found in milk that shape the gut microbiome of infants. The activity of an endo-β-N-acetylglucosaminidase from B. longum subsp. infantis (B. infantis) is known to release N-glycans from native milk glycoproteins under physiological conditions. We investigated whether this enzyme is active in vivo in breastfed infants fed B. infantis EVC001. Using mass spectrometry, we found 19 N-glycans related to human milk glycoproteins increased in abundance, similar to previous work using bovine milk glycoproteins, and these 19 N-glycans matched unique specificities of this enzyme. Twenty N …


Effects Of A Comprehensive Nutrition Education Programme To Change Grade 4 Primary-School Students’ Eating Behaviours In China, Lian Qian, Ian M. Newman, Lok-Wa Yuen, Weijing Du, Duane F. Shell Jan 2019

Effects Of A Comprehensive Nutrition Education Programme To Change Grade 4 Primary-School Students’ Eating Behaviours In China, Lian Qian, Ian M. Newman, Lok-Wa Yuen, Weijing Du, Duane F. Shell

Department of Educational Psychology: Faculty Publications

Objective: As part of a national initiative to reduce child obesity, a comprehensive school-based nutrition education intervention to change eating behaviours among grade 4 primary-school students was developed, implemented and evaluated. Design: The intervention was developed by school staff, with technical assistance from outside health education specialists. The programme included school facility upgrades, school teacher/staff training, curriculum changes and activities for parents. Student scores on nine key eating behaviours were assessed prior to and after the programme. The quality of programme implementation in the schools was monitored by technical assistance teams. Setting: Shandong Province (high household income) and Qinghai Province …


Research Output Of Icar-Indian Institute Of Horticultural Research: A Scientometric Study, Suresh N, Thanuskodi S Dr Jan 2019

Research Output Of Icar-Indian Institute Of Horticultural Research: A Scientometric Study, Suresh N, Thanuskodi S Dr

Library Philosophy and Practice (e-journal)

This paper deals with the analysis of research output of ICAR- Indian Institute of Horticulture, Bangalore (ICAR-IIHR) during 1989 to 2018 appeared in web of science database. It attempts to analyze the growth and development of research activity of ICAR-IIHR as reflected in publications output in web of science database. Data for a study is total of 1095 have been downloaded and analyzed according to objectives. The study reveals that the growth of literature follows the exponential growth pattern, journal articles are the most published form of literature (90.13%), Indian Journal of Agricultural Sciences followed by Current Science are top …


Diurnal Habitat Selection Of Migrating Whooping Crane In The Great Plains, David M. Baasch, Patrick D. Farrell, Aaron T. Pearse, David A. Brandt, Andrew J. Caven, Mary J. Harner, Greg D. Wright, Kristine L. Metzger Jan 2019

Diurnal Habitat Selection Of Migrating Whooping Crane In The Great Plains, David M. Baasch, Patrick D. Farrell, Aaron T. Pearse, David A. Brandt, Andrew J. Caven, Mary J. Harner, Greg D. Wright, Kristine L. Metzger

United States Geological Survey, Northern Prairie Wildlife Research Center: Publications

Available stopover habitats with quality foraging opportunities are essential for migrating waterbirds, including Whooping Crane (Grus americana). Several studies have evaluated habitats used by Whooping Crane for roosting throughout its migration corridor; however, habitats associated with foraging and other diurnal activities have received less attention. We used data collected from 42 Whooping Crane individuals that included 2169 diurnal use locations within 395 stopover sites evaluated during spring 2013 to fall 2015 to assess diurnal habitat selection throughout the U.S. portion of the migration corridor. We found that Whooping Crane selected wetland land-cover types (i.e., open water, riverine, and semipermanent wetlands) …


A Double Humanized Blt-Mice Model Featuring A Stable Human-Like Gut Microbiome And Human Immune System, Lance Daharsh, Jianshui Zhang, Amanda E. Ramer-Tait, Qingsheng Li Jan 2019

A Double Humanized Blt-Mice Model Featuring A Stable Human-Like Gut Microbiome And Human Immune System, Lance Daharsh, Jianshui Zhang, Amanda E. Ramer-Tait, Qingsheng Li

Nebraska Center for Virology: Faculty Publications

Humanized mice (hu-mice) that feature a functional human immune system have fundamentally changed the study of human pathogens and disease. They can be used to model diseases that are otherwise difficult or impossible to study in humans or other animal models. The gut microbiome can have a profound impact on human health and disease. However, the murine gut microbiome is very different than the one found in humans. There is a need for improved pre-clinical hu-mice models that have an engrafted human gut microbiome. Therefore, we created double hu-mice that feature both a human immune system and stable human-like gut …


Differential Relationship Between Physical Activity And Intake Of Added Sugar And Nutrient-Dense Foods: A Cross-Sectional Analysis, Karsten Koehler, Julie B. Boron, Teresa M. Garvin, Matthew R. Bice, Jeffrey R. Stevens Jan 2019

Differential Relationship Between Physical Activity And Intake Of Added Sugar And Nutrient-Dense Foods: A Cross-Sectional Analysis, Karsten Koehler, Julie B. Boron, Teresa M. Garvin, Matthew R. Bice, Jeffrey R. Stevens

Jeffrey Stevens Publications

A curvilinear relationship exists between physical activity (PA) and dietary energy intake (EI), which is reduced in moderately active when compared to inactive and highly active individuals, but the impact of PA on eating patterns remains poorly understood. Our goal was to establish the relationship between PA and intake of foods with varying energy and nutrient density. Data from the 2009–2010 United States National Health and Nutrition Examination Survey were used to include a Dietary Screener Questionnaire for estimated intakes of added sugar, fruits and vegetables, whole grains, fiber, and dairy. Participants (n = 4766; 49.7% women) were divided into …


The Role Of Isothiocyanates As Cancer Chemo‐Preventive, Chemo‐Therapeutic And Anti‐Melanoma Agents, Melina Mitsiogianni, Georgios Koutsidis, Nikos Mavroudis, Dimitrios T. Trafalis, Sotiris Botaitis, Rodrigo Franco, Vasilis Zoumpourlis, Tom Amery, Alex Galanis, Aglaia Pappa, Mihalis I. Panayiotidis Jan 2019

The Role Of Isothiocyanates As Cancer Chemo‐Preventive, Chemo‐Therapeutic And Anti‐Melanoma Agents, Melina Mitsiogianni, Georgios Koutsidis, Nikos Mavroudis, Dimitrios T. Trafalis, Sotiris Botaitis, Rodrigo Franco, Vasilis Zoumpourlis, Tom Amery, Alex Galanis, Aglaia Pappa, Mihalis I. Panayiotidis

School of Veterinary and Biomedical Sciences: Faculty Publications

Many studies have shown evidence in support of the beneficial effects of phytochemicals in preventing chronic diseases, including cancer. Among such phytochemicals, sulphur‐containing compounds (e.g., isothiocyanates (ITCs)) have raised scientific interest by exerting unique chemopreventive properties against cancer pathogenesis. ITCs are the major biologically active compounds capable of mediating the anticancer effect of cruciferous vegetables. Recently, many studies have shown that a higher intake of cruciferous vegetables is associated with reduced risk of developing various forms of cancers primarily due to a plurality of effects, including (i) metabolic activation and detoxification, (ii) inflammation, (iii) angiogenesis, (iv) metastasis and (v) regulation …


Viral Emergence In Marine Mammals In The North Pacific May Be Linked To Arctic Sea Ice Reduction, Elizabeth Vanwormer, J. A.K. Mazet, A. Hall, V. A. Gill, P. L. Boveng, J. M. London, T. Gelatt, B. S. Fadely, M. E. Lander, J. Sterling, V. N. Burkanov, R. R. Ream, P. M. Brock, L. D. Rea, B. R. Smith, A. Jeffers, M. Henstock, M. J. Rehberg, K. A. Burek-Huntington, S. L. Crosby, J. A, Hammond, T. Goldstein Jan 2019

Viral Emergence In Marine Mammals In The North Pacific May Be Linked To Arctic Sea Ice Reduction, Elizabeth Vanwormer, J. A.K. Mazet, A. Hall, V. A. Gill, P. L. Boveng, J. M. London, T. Gelatt, B. S. Fadely, M. E. Lander, J. Sterling, V. N. Burkanov, R. R. Ream, P. M. Brock, L. D. Rea, B. R. Smith, A. Jeffers, M. Henstock, M. J. Rehberg, K. A. Burek-Huntington, S. L. Crosby, J. A, Hammond, T. Goldstein

School of Veterinary and Biomedical Sciences: Faculty Publications

Climate change-driven alterations in Arctic environments can influence habitat availability, species distributions and interactions, and the breeding, foraging, and health of marine mammals. Phocine distemper virus (PDV), which has caused extensive mortality in Atlantic seals, was confirmed in sea otters in the North Pacific Ocean in 2004, raising the question of whether reductions in sea ice could increase contact between Arctic and sub-Arctic marine mammals and lead to viral transmission across the Arctic Ocean. Using data on PDV exposure and infection and animal movement in sympatric seal, sea lion, and sea otter species sampled in the North Pacific Ocean from …


High-Quality Genome-Scale Metabolic Modelling Of Pseudomonas Putida Highlights Its Broad Metabolic Capabilities, Juan Nogales, Joshua Mueller, Steinn Gudmundsson, Francisco J. Canalejo, Estrella Duque, Jonathan Monk, Adam M. Feist, Juan Luis Ramos, Wei Niu, Bernhard O. Palsson Jan 2019

High-Quality Genome-Scale Metabolic Modelling Of Pseudomonas Putida Highlights Its Broad Metabolic Capabilities, Juan Nogales, Joshua Mueller, Steinn Gudmundsson, Francisco J. Canalejo, Estrella Duque, Jonathan Monk, Adam M. Feist, Juan Luis Ramos, Wei Niu, Bernhard O. Palsson

Department of Chemical and Biomolecular Engineering: Faculty Publications

Genome-scale reconstructions of metabolism are computational species-specific knowledge bases able to compute systemic metabolic properties. We present a comprehensive and validated reconstruction of the biotechnologically relevant bacterium Pseudomonas putida KT2440 that greatly expands computable predictions of its metabolic states. The reconstruction represents a significant reactome expansion over available reconstructed bacterial metabolic networks. Specifically, iJN1462 (i) incorporates several hundred additional genes and associated reactions resulting in new predictive capabilities, including new nutrients supporting growth; (ii) was validated by in vivo growth screens that included previously untested carbon (48) and nitrogen (41) sources; (iii) yielded gene essentiality predictions showing large accuracy …


Development Of Chlorophyll-Meter-Index-Based Dynamic Models For Evaluation Of High-Yield Japonica Rice Production In Yangtze River Reaches, Ke Zhang, Xiaojun Liu, Syed Tahir Ata-Ul-Karim, Songyang Li, Brian Krienke, Songyang Li, Qiang Cao, Yan Zhu, Weixing Cao, Yongchao Tian Jan 2019

Development Of Chlorophyll-Meter-Index-Based Dynamic Models For Evaluation Of High-Yield Japonica Rice Production In Yangtze River Reaches, Ke Zhang, Xiaojun Liu, Syed Tahir Ata-Ul-Karim, Songyang Li, Brian Krienke, Songyang Li, Qiang Cao, Yan Zhu, Weixing Cao, Yongchao Tian

Department of Agronomy and Horticulture: Faculty Publications

Accurate estimation of the nitrogen (N) spatial distribution of rice (Oryza sativa L.) is imperative when it is sought to maintain regional and global carbon balances. We systematically evaluated the normalized differences of the soil and plant analysis development (SPAD) index (the normalized difference SPAD indexes, NDSIs) between the upper (the first and second leaves from the top), and lower (the third and fourth leaves from the top) leaves of Japonica rice. Four multi-location, multi-N rate (0–390 kg ha-1) field experiments were conducted using seven Japonica rice cultivars (9915, 27123, Wuxiangjing14, Wunyunjing19, Wunyunjing24, Liangyou9, and Yongyou8). Growth …