Digital Commons Network^™

Carotenoids As Neuroprotective Agents In Multiple Sclerosis: Pathways, Mechanisms, And Clinical Prospects, Elham Nadimi, Shirin Jamal Omidi, Mahshad Ghasemi, Mohammad Hashem Hashempur, Aida Iraji

Faculty, Staff and Student Publications

Multiple sclerosis (MS) is a chronic autoimmune andneurodegenerative disorder affecting the central nervous system (CNS), characterized by demyelination and neuroinflammatory responses, oxidative stress, and immune dysregulation. The global incidence of MS is rising, demonstrating the necessity for new therapeutic agents against its complex pathophysiology. Carotenoids, naturally pigments with strong antioxidant, anti-inflammatory, immunomodulatory, and neuroprotective activities, have been recognized as promising candidates to target MS.The antioxidant effect of astaxanthin, lycopene, β-carotene, crocin, and lutein resulted from the deactivation of reactive oxygen species (ROS), preservation of mitochondrial integrity, and prevention of lipid peroxidation. Additionally, carotenoids regulate inflammatory pathways by suppressing NF-κB activation, …

Tirzepatide For The Maintenance Of Body Weight Reduction: Rationale, Design, And Baseline Characteristics Of Surmount-Maintain, Deborah B Horn, Louis J Aronne, Sean Wharton, Harold E Bays, Elisa Gomez-Valderas, Avigdor D Arad, Palash Sharma, Julia P Dunn, Cagri Senyucel, Clare J Lee

Faculty, Staff and Student Publications

Objective: SURMOUNT-MAINTAIN aims to evaluate the efficacy and safety of reducing the tirzepatide dose and/or continuing the maximum tolerated dose (MTD) versus placebo in maintaining body weight (BW) reduction achieved with tirzepatide MTD.

Methods: This Phase 3b, multicenter, randomized, parallel-arm, double-blinded, placebo-controlled, 52-week clinical trial is in progress comparing treatment with once weekly tirzepatide (5 mg and/or MTD of 15 mg or 10 mg) versus placebo in achieving BW reduction maintenance from the initial 60-week open-label weight-loss period on tirzepatide MTD, in adults with obesity (BMI ≥ 30 kg/m2 or ≥ 27 kg/m2 with ≥ 1 obesity-related comorbidity, excluding type …

Association Between Weight Stigma Experiences In Healthcare And Self-Reported Healthcare Avoidance In A National Sample., Kathleen M. Robinson, Aaron M. Scherer, Alithea N. Zorn, Michelle A. Mengeling, Helena Laroche

Manuscripts, Articles, Book Chapters and Other Papers

OBJECTIVES: Although weight stigma in healthcare is common, existing measures may not capture the full range of patients' weight stigma experiences in clinical practice. We aimed to examine how physical examination by healthcare providers, communication, and the built environment perpetuate weight stigma and impact healthcare avoidance. Items from the previously developed Weight Stigma in Healthcare Inventory (WSHCI) were tested to assess weight stigma experiences and assess association with healthcare avoidance.

METHODS: Two sample groups, identified through ResearchMatch and a Qualtrics survey panel, completed the WSHCI online. We analyzed the association between individual items and healthcare avoidance, and between a summation …

Cancer-Associated Fibroblasts As Mediators Of Tissue Microenvironment Remodeling In Cancer, Fernanda G Kugeratski, Emily J Kay, Sara Zanivan

Faculty, Staff and Student Publications

Cancer-associated fibroblasts (CAFs) are a multifunctional cell population of solid tumors that substantially remodel the tumor microenvironment (TME). The combination of single-cell and spatial technologies with elegant mouse models and analysis of patient samples is enabling unprecedented advances in the characterization of CAF origins, heterogeneity, and functions within the TME. As such, the field is now evolving to delineate tissue-specific subpopulations of CAFs, their markers, and the biological context in which each subset presents with a tumor-promoting or a tumor-restraining function. In this timely review, we discuss recent advances in CAF biology in the context of emerging areas of interest …

Design Of A Maintenance Protocol Based On Bipolar Neutrosophic Analysis For Severe Depression, Karina Alejandra Álvarez Lino

Neutrosophic Sets and Systems

Severe depression has been one of the leading causes of disability worldwide and maintains a high risk of relapses even after successful treatment, especially in medium-sized cities in Latin America. Therefore, this study focused on the design of a clinical maintenance protocol based on Acceptance and Commitment Therapy (ACT), aimed at young adults residing in Ambato, Ecuador, who had previously received Cognitive-Behavioral Therapy (CBT). To this end, a bipolar neutrosophic analysis of depression was conducted to determine the attributes that impact the identified patients and define the design of the proposal. The designed protocol was structured into eight group sessions, …

The Weight Of Stigma, Rebekah A. King, Michael S. Sinha

Cardozo Journal of Equal Rights & Social Justice

Many health care providers, both implicitly and explicitly, perpetuate stigma in their treatment of patients classified as obese. While medical professionals understand that a one-size-fits-all approach to treatment is ineffective, patients classified as obese are frequently offered limited treatment options that fail to account for their unique needs. Access to a range of effective treatment options has historically been limited, but new GLP-1 receptor agonist medicines like Wegovy (semaglutide) and Zepbound (tirzepatide), have shown incredible promise in addressing the obesity crisis. Unfortunately, these transformative drugs are costly, in high demand, and not widely covered by insurance, rendering them inaccessible for …

Bridging The Rural Telehealth Divide, Deborah Farringer

Law Faculty Scholarship

This article examines the historical development, regulatory landscape, and post-pandemic future of telehealth in the United States, with a particular focus on its original purpose: improving access to care for rural populations. Although Congress first authorized Medicare reimbursement for telehealth in 1997 to alleviate rural health disparities, federal and state regulatory frameworks—especially restrictions on originating sites, licensure rules, and HIPAA-driven technology requirements—significantly limited adoption for more than two decades. The COVID-19 public health emergency triggered sweeping temporary waivers that removed geographic limitations, permitted the use of common communication technologies, liberalized supervision and prescribing rules, and allowed audio-only encounters. These changes …

Flies: Nature’S Hidden Helpers, A Science Literacy Project Exploring Beneficial And Pest Insects, Natalie Johnston

Department of Entomology: Distance Master of Science Projects

A science literacy project for elementary learners exploring beneficial and pest insects with a focus on flies, nature's hidden helpers.

This project demonstrates that science literacy can be cultivated through experiential and interdisciplinary teaching. Future developments could include digital tools for compost monitoring, citizen science participation, or expanded studies of other decomposer species. Cross-curricular collaboration with language arts and art education can further strengthen the integration of creativity and evidence-based reasoning.

Ultimately, this work reaffirms that even small organisms—like flies—can inspire big learning outcomes. By integrating science literacy with sustainability education, we prepare students to think critically about ecological relationships …

Experimental Insights Into High Background Radiation: Reduced Cancer Risks In A Murine Model Study, S. M.J. Mortazavi, M. Arshadi, B. F. Baha'addini Baigy Zarandi, J. S. Welsh, H. Mozdarani, M. Haghani, N. Jooyan, S. Nematollahi, Negar Azarpira, Lembit Sihver

Informatics and Engineering Systems Faculty Publications

Background: Natural background radiation varies geographically and has potential implications for cancer development. High-level natural radiation areas (HLNRAs), like Ramsar, Iran, offer unique opportunities to study the biological effects of radiation exposure. This study investigates the relationship between high background radiation and tumor progression in a murine model. Materials and Methods: Thirty-two C57BL/6 mice were exposed to varying levels of natural radiation (0.097 μSv/h to 9.24 μSv/h) for two months, simulating conditions in Ramsar. Mice were divided into four groups based on radiation intensity. After exposure, 1106 B16-F10 melanoma cells were injected subcutaneously, and tumor growth was monitored for 24 …

Institute For Global Health And Development : Issue 12 - October 2025, Institute For Global Health And Development

IGHD Newsletters

• Dr. Bhutta Awarded the Virchow Prize 2025 For Global Health
• Mapping Climate Vulnerability and Resilience Across the Prepare Pakistan Project – Promoting Climate Resilience, Pakistan’s High-Risk Districts
• Choice Project Dissemination Workshop Held in Accelerating Progress Towards Health and Health-Related SDGS Nairobi
• Farhana Tabassum Attends the Inauguration Of “Imagining Life” At the Climate Action Center, Karachi
• IGHD Participates in the Green Zameen Fellowship on Sustainable Energy Transition
• IGHD Team Leads Systematic Reviews & Meta-Analysis
• Empowering Research in Maternal Health Dr. Khadija Vadsaria Completes Her PhD at Aga Khan University
• Climate Change and Maternal Health Dr. Jai Das Featured in the Economist …

Preliminary Investigation Of Nitrogen Rate Influence On Irrigated Bermudagrass Forage Production, Bronc Finch, Lance Blythe

Crop, Soil and Environmental Sciences Faculty Publications and Presentations

Bermudagrass (Cynodon dactylon) forage production recommendations are often developed in natural environments with available water limitations, often resulting in highly variable responses and lower average responses. As farmland ownership changes and agriculture and irrigation technologies become more affordable the amount of irrigated hay production has increased. While much of the agronomic management does not differ between rain-fed and irrigated environments, nutrient use and uptake dynamics may. This requires a reevaluation and potential adjustment of current recommendations to allow for increased yield potential of irrigated production systems without detrimental impacts on the system. The objective of this study was to identify …

The Case For Using Student-Generated Goals To Cultivate Strong Readers, Heather Anne Wyman

Theses and Dissertations

This mixed-methods action research study explored how to motivate seventh-grade students to become stronger readers. I empowered my students by giving them the autonomy to set their own Lexile goals and develop plans to reach them, offering goal-setting lessons along with feedback and support. Students were motivated to meet the goals they created. Lexile assessment data from two benchmark periods enabled me to determine students’ growth, and survey and interview data helped me to determine their perceptions of their increase in self-efficacy and motivation to achieve. While most students did not meet their self-identified Lexile goals, most made academic progress, …

October 2025, Swosu Bulldog Wellness Committee

SWOSU BULLDOG WELLNESS

• October is National Dental Hygiene Month!
• Reminder: YOGA class Oct. 14th for SWOSU employees
• Spooktacular Step Challenge
• Home Fire Safety
• Wellness Committee has three standing desks to loan out
• National Family Health Month
• Autumn Word Search

Insect Pests Of Wheat In North India: A Comprehensive Review Of Their Bio-Ecology And Integrated Management Strategies, Gurveer Singh, Neelendra K. Joshi

Entomology and Plant Pathology Faculty Publications and Presentations

Wheat (Triticum aestivum L.) is a vital food crop for majority of the world's population. However, its yield potential is significantly threatened by insect pests, which adversely affect production, quality, and overall food security. The diverse array of insect pests throughout wheat's growth stages necessitates a comprehensive understanding of their interactions with wheat cultivation. This review critically assesses the diversity, biology, ecology, and management strategies of major insect pests in North India, including aphids, termites, pink stem borer, gram pod borer, armyworm, and brown wheat mite. These pests infest wheat at various growth stages, posing significant challenges to sustainable production. …

Reducing Aspiration Pneumonia By Implementing An Enhanced Oral Care Toolkit, Jennifer London

All Doctor of Nursing Practice (DNP) Scholarly Projects

Problem: Oral care is essential for reducing bacteria and preventing aspiration pneumonia. The risk of aspiration pneumonia increases when protocols are not followed. In 2024, a regional hospital in the Midwest United States spent approximately one million dollars on the preventable healthcare-associated infection known as aspiration pneumonia. A pre-project chart audit of 100 random patient charts on a medical/surgical step-down unit revealed that only 1 of the 100 charts had oral care documented as completed.

Aim of the Project: The primary aims of this project were to increase nursing documentation of oral care by 50% and to decrease …

Improving Pain Assessment After Bedside Percutaneous Endoscopic Gastrostomy (Peg) Placement, Sherman Cotton

All Doctor of Nursing Practice (DNP) Scholarly Projects

Problem: Baseline audits at a 44-bed critical-illness recovery hospital showed low reliability in two post-PEG practices: (1) pain reassessment within 90 minutes of an intervention and (2) complete PEG-site documentation (skin, drainage, tube position/measurement). Baseline performance averaged 55% and 62%, both of which were below the organization’s 90% benchmark.

Aim of the Project: From May to July 2025 (12 weeks), improve on-time pain reassessment and ensure PEG-site documentation reaches at least 90%, maintaining this level for three or more consecutive weeks; monitor workload to prevent increases in perceived charting time and ensure safety by avoiding a rise in PEG-related …

Adapting To Inflationary Pressures: Household Coping Strategies In Urban Egypt (2016– 2025), Mohamed Mohamed Ashraf Kamal

Theses and Dissertations

Over the past decade, Egypt has faced persistent economic challenges including repeated currency devaluations, high inflation rates, subsidy reforms such as the gradual reduction of food and energy subsidies, and the ripple effects of global crises that have significantly impacted household well-being, especially in urban areas. These pressures have eroded purchasing power and heightened food insecurity, especially among low- and middle-income families. Although substantial attention has been paid to macroeconomic indicators, there remains a critical gap in understanding how households adapt on a daily basis to manage financial stress and sustain their livelihoods. This inquiry is especially timely, as household …

Fcrh Honors Program: Fall 2025 Program Highlights, Fcrh Honors Program

FCRH Honors Program Newsletters and Reports

No abstract provided.

The Motherhood Penalty On Health: Evidence From China, Ang Sun, Fang Xia, Xuan Zhang

Research Collection School Of Economics

Understanding women’s physical and mental well-being following childbirth is critical for informing policies on labor market equity, family support, and fertility. Using event study methods and panel data from China, we document a persistent motherhood penalty in both physical and mental health, whereas the health impacts on fathers are minimal. While mothers experience a temporary reduction in paid work hours, they face a sustained increase in unpaid domestic labor — housework and childcare — resulting in a net increase in total work time. This additional workload likely contributes to deterioration in health. Mothers are also more likely to engage in …

University Of San Diego Magazine Fall 2025, Publications Department

University of San Diego Magazine (1992- )

Beauty, Goodness and Truth; Dear Toreros; Around Alcalá Park; At The Edge of It All; Faith In Action; Torero Spotlight; Torero Athletics; Toreros Making Waves; In Memoriam; Leading With Love

Relationship Between Dietary Probiotic Consumption And Cognitive Functioning In Older Adults: A 2011-2014 Nhanes Study, Lauren Weber, J. Gieng, Ashwini Wagle

Faculty Research, Scholarly, and Creative Activity

Background

Consumption of probiotics has recently been associated with a reduced risk of cognitive decline due to its anti-inflammatory effect on the brain, via the gut-brain-axis. Current studies with probiotic supplementation indicate that probiotics may play an important role in slowing the rate of cognitive decline and protecting memory. The purpose of this study was to evaluate a potential relationship between cognitive decline and dietary intake of probiotics.

Methods

This study utilized data from NHANES, both 2011-2012 and 2013-2014 cycles. Categorical variables were analyzed using chi-square tests, and continuous variables were analyzed using General Linear Models. Participants (n = 2,689) …

Advancing Medical Education With Lifestyle Medicine: A Comprehensive Program Evaluation Using The Kirkpatrick Framework, Shanna L. Mello

Electronic Theses and Dissertations

This dissertation examined how a U.S. national lifestyle medicine residency curriculum influenced resident learning and practice using a program evaluation paradigm with a convergent mixed methods design guided by Kirkpatrick’s four-level evaluation model. The problem addressed was the persistent gap between evidence for lifestyle interventions and the limited preparation residents receive to deliver lifestyle counseling in routine care. The purpose of the study was to evaluate changes in residents’ reactions, learning, and clinical behaviors and to identify early patient-level signals and the implementation conditions that enabled or constrained behavior change. Quantitative methods analyzed archived pre- and posttraining surveys from 148 …

Effective Practices In Working With Academic Coaches, Tracia M. Forman, Jessica M. Sanchez

Health & Biomedical Sciences Faculty Publications

As online education grows, instructional teams with academic coaches have become increasingly valuable in higher education. Coaches play crucial roles in fostering student engagement, supporting active learning, and delivering timely feedback, particularly in large online courses. Recent mixed-method research examined effective coach integration into online instructional teams by analyzing faculty characteristics, behaviors, preferences, attitudes, and knowledge. The study identified successful strategies and best practices for faculty-coach collaboration, providing actionable insights for instructors. This research expands our understanding of how team-based approaches can enhance educational quality in virtual environments, contributing meaningfully to ongoing discussions about online teaching effectiveness and the strategic …

Southeast Asia Higher Education Changes And Emerging Futures, Muhammad Hali Aprimadya, Lily Kong, Angel Calderon, Hamish Coates

Research Collection School of Social Sciences

This paper unpacks recent developments and future directions in Southeast Asian higher education. It takes stock of higher education systems in three selected countries, Australia, Indonesia and Singapore. It sketches these systems, distils several changes around 2024, and discusses emerging directions for education, research and universities. The paper concludes by looking at what is required to catalyse transformations likely to impel future progress.

Effectiveness And Assessment Of A Culturally-Tailored Carbohydrate Counting Tool For South Asians With Diabetes: A Practitioner’S Evaluation, Ashwini Wagle

Faculty Research, Scholarly, and Creative Activity

South Asians are at a higher risk for type 2 diabetes compared to many other racial and ethnic groups. Dietary patterns play a significant role and are a modifiable risk factor. This study aimed to evaluate a South Asian carbohydrate counting tool developed by the researcher, assessed by Registered Dietitians Nutritionists and Certified Diabetes Care and Education Specialists. Using nutrition communication theory and the transtheoretical model, the tool included a comprehensive list of commonly consumed South Asian foods and sample vegetarian and non-vegetarian meals (1800e2100 kcal). Sixty-five participants received the tool and a training slide deck. A 40-item questionnaire assessed …

Spinal Cord Injury, Children's Mercy Kansas City

Clinical Pathways

No abstract provided.

Taxes And Tournaments, Alex Raskolnikov

Faculty Scholarship

What is the best way to reduce economic inequality? Economists, lawyers, political philosophers, and politicians have pondered this question for decades. Yet there is another group of savvy and highly motivated individuals who have been thinking about redistribution for just as long. Commissioners of the National Football League, the National Basketball Association, the National Hockey League, and Major League Baseball, together with team owners and player unions, have been inventing and reinventing ways to redistribute resources, and they continue to do so today. The same is true of the President of National Collegiate Athletic Association, along with the heads of …

Ccfan Summer Meals Success Story, Joy Gagnon

UNH Cooperative Extension

No abstract provided.

Ccfan Brochure 2025, Joy Gagnon

UNH Cooperative Extension

No abstract provided.

2025 Ccfan Accomplishments, Mikayla Cerney

UNH Cooperative Extension

No abstract provided.