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2019

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Articles 63721 - 63750 of 65574

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Comparison Of Ultrasound-Guided Transversus Abdominis Plane Block, Quadratus Lumborum Block, And Caudal Epidural Block For Perioperative Analgesia In Pediatric Lower Abdominal Surgery, Celal Bulut İpek, Deni̇z Kara, Si̇nan Yilmaz, Serdar Yeşi̇ltaş, Asim Esen, Shai̇naaz Dooply Su Sander Lwi̇n, Kazi̇m Karaaslan, Ayda Türköz Jan 2019

Comparison Of Ultrasound-Guided Transversus Abdominis Plane Block, Quadratus Lumborum Block, And Caudal Epidural Block For Perioperative Analgesia In Pediatric Lower Abdominal Surgery, Celal Bulut İpek, Deni̇z Kara, Si̇nan Yilmaz, Serdar Yeşi̇ltaş, Asim Esen, Shai̇naaz Dooply Su Sander Lwi̇n, Kazi̇m Karaaslan, Ayda Türköz

Turkish Journal of Medical Sciences

Background/aim: Despite different regional anesthesia techniques used to provide intraoperative and postoperative analgesia in pediatric patients, the analgesic effectiveness of peripheral nerve blockades with minimal side effect profiles have not yet been fully determined.We aimed to compare the efficacy of ultrasound-guided transversus abdominis plane (TAP) block, quadratus lumborum (QL) block, and caudal epidural block on perioperative analgesia in pediatric patients aged between 6 months and 14 years who underwent elective unilateral lower abdominal wall surgery.Materials and methods: Ninety-four patients classified under the American Society of Anesthesiologists physical status classification system as ASA I or ASA II were randomly divided into …

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Normative Hippocampal Volumetric Measurements Using Magnetic Resonance Imaging, Meltem Özdemi̇r, Handan Soysal, Önder Eraslan, Alper Di̇lli̇ Jan 2019

Normative Hippocampal Volumetric Measurements Using Magnetic Resonance Imaging, Meltem Özdemi̇r, Handan Soysal, Önder Eraslan, Alper Di̇lli̇

Turkish Journal of Medical Sciences

Background/aim: A wide variety of neurological and psychiatric disorders have been shown to be closely related to changes in hippocampal volume (HV). It appears that hippocampal volumetry will be an indispensable part of clinical practice for a number of neuropsychiatric disorders in the near future. The aim of this study was to establish a normative data set for HV according to age and sex in the general population.Materials and methods: Hippocampal magnetic resonance imaging scans of 302 healthy volunteers were obtained using a 1.5 T unit with a 20-channel head coil. The hippocampal volumetric assessment was conducted using the volBrain …

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Evaluation Of Interleukin-23 Receptor (Il-23r) Gene Polymorphisms And Serum Il-23 Levels In Patients With Psoriasis, Başak Fi̇li̇z, Mehmet Yildirim, Kuyaş Heki̇mler Öztürk, Fevzi̇ye Burcu Şi̇ri̇n, Seda Çeli̇k, İjlal Erturan, Selma Korkmaz, Hi̇kmet Orhan Jan 2019

Evaluation Of Interleukin-23 Receptor (Il-23r) Gene Polymorphisms And Serum Il-23 Levels In Patients With Psoriasis, Başak Fi̇li̇z, Mehmet Yildirim, Kuyaş Heki̇mler Öztürk, Fevzi̇ye Burcu Şi̇ri̇n, Seda Çeli̇k, İjlal Erturan, Selma Korkmaz, Hi̇kmet Orhan

Turkish Journal of Medical Sciences

Background/aim: IL-23R gene polymorphisms and the association of these polymorphisms with serum IL-23 levels were investigated in patients with psoriasis in the current study. Materials and methods: Sixty-seven patients with psoriasis who were admitted to our dermatology outpatient clinic and 67 healthy controls were included in the study. Polymorphisms of the IL-23R gene were determined by KASP-PCR method, and serum IL-23 levels were determined by ELISA method.Results: The distribution of IL-23R gene polymorphisms rs2201841, rs11209026, rs7530511, rs1343152, and rs11465804 was not significantly different in the patient and control groups. The AA genotype of the rs2201841 locus in males and the …

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Pyogenic Granuloma And Nodular Kaposi?S Sarcoma: Dermoscopic Clues For The Differential Diagnosis, Ömer Faruk Elmas, Necmetti̇n Akdeni̇z, Emi̇ne Müge Acar, Asuman Ki̇li̇tçi̇ Jan 2019

Pyogenic Granuloma And Nodular Kaposi?S Sarcoma: Dermoscopic Clues For The Differential Diagnosis, Ömer Faruk Elmas, Necmetti̇n Akdeni̇z, Emi̇ne Müge Acar, Asuman Ki̇li̇tçi̇

Turkish Journal of Medical Sciences

Background/aim: Pyogenic granuloma (PG)-like nodular Kaposi?s sarcoma (KS) has been previously demonstrated in several studies. However, to the best of our knowledge, no original study investigating the dermoscopic differential diagnosis of PG and KS exists in the relevant literature. In this study we aimed to identify dermoscopic findings providing useful clues to differential diagnosis between the two entities.Materials and methods: Patients with histopathologically confirmed PG or nodular KS were included in the study. Demographic, clinical, dermoscopic, and histopathological findings of the cases were retrospectively reviewed. Results: The most common finding observed in PG was red structureless areas (80.00%), followed by …

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Importance Of 14-3-3eta, Anti-Carp, And Anti-Sa In The Diagnosis Of Seronegative Rheumatoid Arthritis, Emrah Salman, Sali̇h Çeti̇ner, Bariş Boral, Fi̇li̇z Ki̇bar, Eren Erken, Emi̇ne Duygu Ersözlü, Suade Özlem Badak, Reyhan Bi̇li̇ci̇ Salman, Yaşar Sertdemi̇r, Alev Çeti̇n Duran, Akgün Yaman Jan 2019

Importance Of 14-3-3eta, Anti-Carp, And Anti-Sa In The Diagnosis Of Seronegative Rheumatoid Arthritis, Emrah Salman, Sali̇h Çeti̇ner, Bariş Boral, Fi̇li̇z Ki̇bar, Eren Erken, Emi̇ne Duygu Ersözlü, Suade Özlem Badak, Reyhan Bi̇li̇ci̇ Salman, Yaşar Sertdemi̇r, Alev Çeti̇n Duran, Akgün Yaman

Turkish Journal of Medical Sciences

Background/aim: Rheumatoid arthritis (RA) is an autoimmune disease characterized by synovial inflammation. The study aimed to assess serum 14-3-3eta, anti-CarP, and anti-Sa in seronegative RA (SNRA) patients who were treatment-naïve as well as in healthy subjects. This is the first study in the literature to examine these autoantibodies together in SNRA patients. Materials and methods: Forty-five treatment-naïve SNRA patients and 45 healthy subjects were recruited. Drugs change the levels of autoantibodies; therefore, patients who took any medication had been excluded from our study. Anti-carbamylated protein, anti-Sa, and 14-3-3eta were measured by using three different ELISA kits.Results: Median serum concentration of …

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Comparison Of 2-Year Clinical And Radiological Outcomes Between Volar Plating And External Fixation With Additional K-Wires For Ao Type C Distal Radius Fractures, Özgür Çi̇çekli̇, Erhan Şükür, Alauddi̇n Kochai̇, Levent Bayam, İzzet Bi̇ngöl, Uğur Özdemi̇r Jan 2019

Comparison Of 2-Year Clinical And Radiological Outcomes Between Volar Plating And External Fixation With Additional K-Wires For Ao Type C Distal Radius Fractures, Özgür Çi̇çekli̇, Erhan Şükür, Alauddi̇n Kochai̇, Levent Bayam, İzzet Bi̇ngöl, Uğur Özdemi̇r

Turkish Journal of Medical Sciences

Background/aim: Surgical treatment of distal intraarticular radius fractures remains controversial. Our aim was to compare the clinical and radiological outcomes between volar plating (VP) and external fixation (EF) for distal intraarticular radius fractures two years postoperatively. Materials and methods: This retrospective study included 59 patients with 62 intraarticular AO Type C distal radius fractures. We distinguished two groups: patients treated with internal fixation (volar locking plate, VP group: 41 fractures), and patients treated with an external fixator and K-wires (EF group: 21 fractures). The clinical assessment included range of motion, grip strength, disability of the arm, shoulder, and hand (DASH), …

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Quantitative Analysis Of The Optic Nerve Head Parameters In Patients With Age-Related Macular Degeneration, Mert Şi̇mşek, Mehmet Çitirik, Serdar Özateş, Tülay Şi̇mşek Jan 2019

Quantitative Analysis Of The Optic Nerve Head Parameters In Patients With Age-Related Macular Degeneration, Mert Şi̇mşek, Mehmet Çitirik, Serdar Özateş, Tülay Şi̇mşek

Turkish Journal of Medical Sciences

Background/aim: To evaluate the topographic parameters of the optic disc of patients with age-related macular degeneration (AMD) by performing confocal scanning laser ophthalmoscopy.Materials and methods: This prospective study included 41 eyes of 41 patients with neovascular AMD, 56 eyes of 56 patients with nonneovascular AMD, and 48 eyes of 48 healthy control subjects. Images of the optic nerve head of all of the participants were obtained using Heidelberg retinal tomography III software 3.1. The following stereometric parameters were measured for each participant: disc area, cup area, rim area, cup volume, rim volume, cup-to-disc ratio, mean cup depth, maximum cup depth, …

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The Frequency Of Raynaud?S Phenomenon In Patients With Methylenetetrahydrofolate Reductase Gene Mutation And Hyperhomocysteinemia, Kadi̇r Serkan Yalçin, Ali̇ Koşar Jan 2019

The Frequency Of Raynaud?S Phenomenon In Patients With Methylenetetrahydrofolate Reductase Gene Mutation And Hyperhomocysteinemia, Kadi̇r Serkan Yalçin, Ali̇ Koşar

Turkish Journal of Medical Sciences

Background/aim: Raynaud?s phenomenon (RP) is not a rare health problem; global prevalence is about 3%?20%. Etiology and pathophysiology of this pathology has not been clarified. There are many precipitating factors resulting in RP. Hyperhomocysteinemia resulting from methylenetetrahydrofolate reductase (MTHFR) gene mutationmay have a role in its etiology. The aim of this study was to observe the frequency of RP in patients with MTFHR gene mutation and hyperhomocysteinemia. Possible relationships among vitamin B12, folic acid, complete blood count (leukocytes and platelets), and c-reactive protein levels and RP were also analyzed. Materials and methods: A total of 388 patients admitted to the …

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Incidence Of Second Primary Malignancies In Patients With Thyroid Cancer In The Turkish Population, Meli̇a Karaköse, İlker Çordan, Mustafa Can, Muhammet Kocabaş, Mustafa Kulaksizoğlu, Feridun Karakurt Jan 2019

Incidence Of Second Primary Malignancies In Patients With Thyroid Cancer In The Turkish Population, Meli̇a Karaköse, İlker Çordan, Mustafa Can, Muhammet Kocabaş, Mustafa Kulaksizoğlu, Feridun Karakurt

Turkish Journal of Medical Sciences

Background/aim: Thyroid cancer is the most common endocrine malignancy. Recently the incidence has been increasing faster compared to other malignancies. Different studies have shown that the incidence of breast cancer in patients followed due to thyroid cancer has increased, and vice versa. The aim of this study was to evaluate the frequency of second primary cancers in the follow-up of patients with thyroid cancer.Materials and methods: In this study, 1196 patients with thyroid cancer were evaluated in the Necmettin Erbakan University Meram Medical School?s Department of Endocrinology between 2004 and 2018. Demographic characteristics and radiological and pathological results of the …

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Tracheal Intubation With The Mcgrath Mac X-Blade Videolaryngoscope In Morbidly Obese And Nonobese Patients, Zehra İpek Arslan, Hadi̇ Ufuk Yörükoğlu Jan 2019

Tracheal Intubation With The Mcgrath Mac X-Blade Videolaryngoscope In Morbidly Obese And Nonobese Patients, Zehra İpek Arslan, Hadi̇ Ufuk Yörükoğlu

Turkish Journal of Medical Sciences

Background/aim: Increased body mass index (BMI) and neck circumference are the two independent predictors of difficult intubation. McGrath MAC X-Blade is a videolaryngoscope specifically designed for difficult intubations. Materials and methods: Eighty patients with the American Society of Anesthesiologists (ASA) physical status I?III undergoing elective surgery requiring endotracheal intubation were enrolled in the study. Patients were divided into two groups, nonobese (BMI < 30) and morbidly obese (BMI > 35). All patients were intubated with the McGrath MAC X-Blade in both groups. View optimization and tube insertion maneuvers such as reinsertion of the device, slight removal of the device, cricoid pressure, handling force, 90° anticlockwise rotation of …

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Nicotinamide N-Methyltransferase Expression And Its Association With Phospho-Akt, P53 Expression, And Survival In High-Grade Endometrial Cancer, Serra Akar, İsmai̇l Harmankaya, Serdar Ugras, Çeti̇n Çeli̇k Jan 2019

Nicotinamide N-Methyltransferase Expression And Its Association With Phospho-Akt, P53 Expression, And Survival In High-Grade Endometrial Cancer, Serra Akar, İsmai̇l Harmankaya, Serdar Ugras, Çeti̇n Çeli̇k

Turkish Journal of Medical Sciences

Background/aim: Nicotinamide N-methyltransferase (NNMT) is an enzyme that is overexpressed in malignancies. NNMT expression has not been previously studied in endometrial cancer (EC). Increased phospho-Akt (pAkt) levels in response to NNMT overexpression have been reported in in vitro studies of different cancer types. We assayed NNMT expression in primary and metastatic high-grade EC and investigated the relationship of NNMT with p53, pAkt, and survival. Materials and methods: NNMT, pAkt, and p53 expressions were assayed in 100 tissue samples of benign endometria, primary EC, and metastatic EC by immunohistochemistry. Results: The NNMT immunoreactivity score was significantly higher in primary high-grade EC …

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Comparison Of Block And Pulsed Radiofrequency Of The Ganglion Impar In Coccygodynia, Ender Si̇r, Sami̇ Eksert Jan 2019

Comparison Of Block And Pulsed Radiofrequency Of The Ganglion Impar In Coccygodynia, Ender Si̇r, Sami̇ Eksert

Turkish Journal of Medical Sciences

Background/aim: Ganglion impar blockis used for the treatment of chronic coccygodynia. Pulsed radiofrequency (PRF) of the ganglion impar is a promising novel technique. The aim of this study was to determine and compare the efficacy of the blockade and PRF of the ganglion impar.Materials and methods: Thirty-nine consecutive patients diagnosed with coccygodynia and treated with a blockade or PRF of the ganglion impar were included in this retrospective study. We compared the ganglion impar block (GIB) group (n = 25) with the ganglion impar pulsed radiofrequency (GIPRF) group (n = 14) in terms of pain intensity and patient satisfaction. We …

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Unclassifiable Non-Cml Classical Myeloproliferative Diseases With Microcytosis: Findings Indicating Diagnosis Of Polycythemia Vera Masked By Iron Deficiency, Eli̇fcan Aladağ Karakulak, Sali̇h Aksu, Haluk Demi̇roğlu, Ni̇lgün Sayinalp, Hakan Göker, İbrahi̇m Celaletti̇n Haznedaroğlu, Osman İlhami̇ Özcebe, Yahya Büyükaşik Jan 2019

Unclassifiable Non-Cml Classical Myeloproliferative Diseases With Microcytosis: Findings Indicating Diagnosis Of Polycythemia Vera Masked By Iron Deficiency, Eli̇fcan Aladağ Karakulak, Sali̇h Aksu, Haluk Demi̇roğlu, Ni̇lgün Sayinalp, Hakan Göker, İbrahi̇m Celaletti̇n Haznedaroğlu, Osman İlhami̇ Özcebe, Yahya Büyükaşik

Turkish Journal of Medical Sciences

Background/aim: Polycythemia Vera (PV) is a myeloproliferative disorder characterized by overproduction of morphologically normal red blood cells (RBCs), granulocytes, and platelets, a phenotype that is caused by a mutation (V617F) in Janus kinase 2 (JAK2). However, JAK2 V617F is also found in approximately 50% of patients with essential thrombocytosis and primary myelofibrosis, rendering its presence nonspecific as a diagnostic test. An increased red cell mass is a major criterion for the diagnosis of PV according to World Health Organization (WHO) 2016 criteria. High hemoglobin (Hgb) or Hematocrit (Hct) are universally used as indicators of an increased red cell mass for …

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Serum Zinc Levels In Seborrheic Dermatitis: A Case-Control Study, Ezgi̇ Aktaş Karabay, Asli Aksu Çerman Jan 2019

Serum Zinc Levels In Seborrheic Dermatitis: A Case-Control Study, Ezgi̇ Aktaş Karabay, Asli Aksu Çerman

Turkish Journal of Medical Sciences

Background/aim:Malassezia colonization, sebaceous gland activity, hormones, immune system defects, environmental factors, and the interactions between these factors are thought to contribute to the pathogenesis of seborrheic dermatitis (SD). Zinc, an essential element, is involved in many biological processes including the ones that contribute to the development of SD. The aim of this study is to evaluate serum zinc levels in patients with SD.Materials and methods: Forty-three patients with SD and 41 healthy controls were enrolled in the study. Disease activity was assessed by the Seborrheic Dermatitis Area and Severity Index by a single dermatologist. Serum zinc levels of all subjects …

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Comparison Of Bactericidal And Fungicidal Efficacy Of Antiseptic Formulations According To En 13727 And En 13624 Standards, Asli Şahi̇ner, Ece Halat, Evren Alğin Yapar Jan 2019

Comparison Of Bactericidal And Fungicidal Efficacy Of Antiseptic Formulations According To En 13727 And En 13624 Standards, Asli Şahi̇ner, Ece Halat, Evren Alğin Yapar

Turkish Journal of Medical Sciences

Background/aim: In this study, the antibacterial and antifungal properties of the five most commonly used antiseptic formulations were evaluated in terms of different contact times and organic conditions. Materials and methods: Solutions of chlorhexidine digluconate, povidone iodine, isopropyl alcohol, hydrogen peroxide, and tincture of iodine were prepared and tested according to European standards EN 13727 and EN 13624 with different parameters.Results: The results showed that isopropyl alcohol (70% v/v) and tincture of iodine (2%) had greater bactericidal and fungicidal activity against the four tested bacteria and two fungi in all conditions.Conclusion: When the results of the five different active substances …

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Shear Wave Versus Strain Elastography In The Differentiation Of Benign And Malignant Breast Lesions, Aykut Gürüf, Mesut Öztürk, İlkay Koray Bayrak, Ahmet Veysel Polat Jan 2019

Shear Wave Versus Strain Elastography In The Differentiation Of Benign And Malignant Breast Lesions, Aykut Gürüf, Mesut Öztürk, İlkay Koray Bayrak, Ahmet Veysel Polat

Turkish Journal of Medical Sciences

Background/aim: To evaluate and compare the diagnostic performances of shear wave elastography (SWE) and strain elastography (SE) in the differentiation of benign and malignant breast lesions.Materials and methods: The current study included 87 breast lesions in 84 patients. The Breast Imaging Reporting and Data System (BIRADS) categories were determined with ultrasound features. The maximum shear wave velocity (SWV), mean SWV, maximum SWV to fat SWV ratio, and mean SWV to fat SWV ratio were measured using SWE. The strain ratio (SR) was calculated as the ratio of lesion strain to the adjacent fat strain using SE. Receiver operating characteristic (ROC) …

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Do Pd-1 And Pd-L2 Expressions Have Prognostic Impact In Hematologic Malignancies?, Serdal Korkmaz, Selahatti̇n Erdem, Ebru Akay, Erdem Arzu Taşdemi̇r, Hati̇ce Karaman, Muzaffer Kekli̇k Jan 2019

Do Pd-1 And Pd-L2 Expressions Have Prognostic Impact In Hematologic Malignancies?, Serdal Korkmaz, Selahatti̇n Erdem, Ebru Akay, Erdem Arzu Taşdemi̇r, Hati̇ce Karaman, Muzaffer Kekli̇k

Turkish Journal of Medical Sciences

Background/aim: PD-1 (programmed death-1) is an immune checkpoint receptor that modulates T-cell activity in peripheral tissues via interaction with its ligands, PD-L1 (programmed death-ligand 1) and PD-L2 (programmed death-ligand 2). Tumor cells upregulate PD-L1 or PD-L2 to inhibit this T lymphocyte attack. Our goal was to determine the PD-1 and PD-L2 expression rates of various hematologic malignancies, and evaluate whether PD-1 and PD-L2 expressions have an impact on prognosis. Materials and methods: For this purpose, pretreatment bone marrow biopsy specimens of 83 patients [42 multiple myeloma (MM), 21 acute leukemia, and 20 chronic lymphocytic leukemia (CLL)] were stained with monoclonal …

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External Validation Of Anastomotic Leakage Risk Analysis System In Patients Who Underwent Colorectal Resection, Sadetti̇n Er, Sabri̇ Özden, Faruk Koca, Bariş Doğu Yildiz, Bülent Cavi̇t Yüksel, Mesut Tez Jan 2019

External Validation Of Anastomotic Leakage Risk Analysis System In Patients Who Underwent Colorectal Resection, Sadetti̇n Er, Sabri̇ Özden, Faruk Koca, Bariş Doğu Yildiz, Bülent Cavi̇t Yüksel, Mesut Tez

Turkish Journal of Medical Sciences

Background/aim: One of the most feared complications after colon resection for carcinoma is anastomotic leakage. Prediction of anastomotic leakage can alter pre- and perioperative management of patients. This study validates an anastomotic leakage prediction system. Materials and methods: Ninety-five patients who underwent colonic resection between 1 January 2016 and 30 January 2017 were included in the study. Patient records and electronic charting system data were used to calculate anastomotic leakage risk on the http://www.anastomoticleak.com/ website.Results: Fifty-six (58.9%) patients were male and thirty-nine (41.1%) were female. The mean age was 61.7 (min: 33, max: 90). Six (6.3%) patients had anastomotic leakage. …

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The Effect Of Isotretinoin On Insulin Resistance And Adipocytokine Levels In Acne Vulgaris Patients, Gonca Soyuduru, Esra Özsoy Adişen, İlkay Özer, Ahmet Burhan Aksakal Jan 2019

The Effect Of Isotretinoin On Insulin Resistance And Adipocytokine Levels In Acne Vulgaris Patients, Gonca Soyuduru, Esra Özsoy Adişen, İlkay Özer, Ahmet Burhan Aksakal

Turkish Journal of Medical Sciences

Recent data draw attention to the effect of body composition, insulin resistance, and adipocytokines to acne vulgaris (AV) development. The aim of this study was to assess the association of AV with insulin resistance and adipocytokine levels and to evaluate the effect of isotretinoin on insulin resistance and adipocytokine levels. Materials and methods: In 29 AV patients and 29 healthy volunteers, body mass index (BMI) and body fat mass (BFM), lipid, adiponectin, leptin, resistin, retinol binding protein-4 (RBP4), and insulin levels were measured and insulin resistance was assessed by HOMA-IR index in serum samples taken twice from patients before and …

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Prevalence Of Multiple Sclerosis In An Urban Population Of Sivas Province In Turkey, Şeyda Fi̇gül Gökçe, Burhanetti̇n Çi̇ğdem, Sanem Nemmezi̇ Karaca, Asli Bolayir, Özlem Kayim Yildiz, Ahmet Suat Topaktaş, Hati̇ce Balaban Jan 2019

Prevalence Of Multiple Sclerosis In An Urban Population Of Sivas Province In Turkey, Şeyda Fi̇gül Gökçe, Burhanetti̇n Çi̇ğdem, Sanem Nemmezi̇ Karaca, Asli Bolayir, Özlem Kayim Yildiz, Ahmet Suat Topaktaş, Hati̇ce Balaban

Turkish Journal of Medical Sciences

Background/aim: Multiple sclerosis (MS) is a common neurological disorder that can be a leading cause of nontraumatic disability in several countries. Recent reports have indicated a moderate to high risk of MS in European countries. In this study, we examined the prevalence of MS in a well-defined urban population of provincial center in Sivas Province in Turkey.Materials and methods: This study sampled all registered residents of urban areas of provincial center in Sivas Province in April 2017 and 2018 January. All the included patients met the McDonald 2010 criteria. Medical records were reviewed, including all available previously acquired magnetic resonance …

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Comparison Of Ga-68 Psma Positron Emission Tomography/Computerized Tomography With Tc-99m Mdp Bone Scan In Prostate Cancer Patients, Rabi̇a Lebri̇z Uslu Beşli̇, Muhammet Sai̇t Sağer, Eli̇fe Akgün, Sertaç Asa, Onur Erdem Şahi̇n, Çeti̇n Demi̇rdağ, Ekrem Güner, Seyedbaresh Razavi̇khosroshahi̇, Emre Karayel, Hüseyi̇n Pehli̇vanoğlu, Aslan Aygün, İlhami̇ Uslu, Zübeyr Talat, Keri̇m Sönmezoğlu Jan 2019

Comparison Of Ga-68 Psma Positron Emission Tomography/Computerized Tomography With Tc-99m Mdp Bone Scan In Prostate Cancer Patients, Rabi̇a Lebri̇z Uslu Beşli̇, Muhammet Sai̇t Sağer, Eli̇fe Akgün, Sertaç Asa, Onur Erdem Şahi̇n, Çeti̇n Demi̇rdağ, Ekrem Güner, Seyedbaresh Razavi̇khosroshahi̇, Emre Karayel, Hüseyi̇n Pehli̇vanoğlu, Aslan Aygün, İlhami̇ Uslu, Zübeyr Talat, Keri̇m Sönmezoğlu

Turkish Journal of Medical Sciences

Background/aim: The aim of our study was to compare Tc-99m MDP bone scan and Ga-68 PSMA PET/CT in terms of detection of bone metastasis in prostate cancer patients. Materials and methods: A total of 28 prostate cancer patients with bone scan and PSMA PET/CT performed within 90 days were retrospectively included in our analysis. All bone lesions were scored as negative (score-0), positive (score-1), or suspicious (score-2) for metastasis by two experienced nuclear medicine physicians. Both patient-based and region-based analyses were made for all osseous lesions. Results: On per-patient analysis; sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), …

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The Effects Of Early Neurodevelopmental Bobath Approach And Mobilization On Quadriceps Muscle Thickness In Stroke Patients, Arzu Güçlü Gündüz, Gökhan Yazici, Çağla Özkul, Hami̇t Küçük, Hale Zeynep Batur Çağlayan, Bi̇jen Nazliel Jan 2019

The Effects Of Early Neurodevelopmental Bobath Approach And Mobilization On Quadriceps Muscle Thickness In Stroke Patients, Arzu Güçlü Gündüz, Gökhan Yazici, Çağla Özkul, Hami̇t Küçük, Hale Zeynep Batur Çağlayan, Bi̇jen Nazliel

Turkish Journal of Medical Sciences

Background/aim: Following stroke, damage to the central nervous system and adaptive changes in muscle tissue are factors responsible for the loss of muscle strength. Even though it is suggested that early physiotherapy and mobilization prevent structural adaptive changes in muscle tissue, studies regarding this issue are insufficient. The aim of this study is to investigate the effects of early physiotherapy and mobilization on quadriceps muscle thickness (QMT) in stroke patients.Materials and methods: Twelve stroke patients who were admitted to the neurology intensive care unit and 13 healthy controls were included in the study. QMT was examined at admission and discharge …

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Evaluation Of The Efficacy Of Epiduroscopic Adhesiolysis In Failed Back Surgery Syndrome, Ayşegül Ceylan, İbrahi̇m Aşik, Güngör Enver Özgenci̇l, Burak Erken Jan 2019

Evaluation Of The Efficacy Of Epiduroscopic Adhesiolysis In Failed Back Surgery Syndrome, Ayşegül Ceylan, İbrahi̇m Aşik, Güngör Enver Özgenci̇l, Burak Erken

Turkish Journal of Medical Sciences

We aimed to compare the results of the treatment of the patients with failed back surgery syndrome (FBSS) by mechanical lysis and steroid hylase injection via epiduroscopy due to their stabilization status and to detect the effect of pathological diagnostic markers on prognosis and ongoing treatment protocol. Materials and methods: Eighty-two patients with FBSS symptoms were included. Two groups were composed as group I (stabilized) and group II (nonstabilized). All patients were evaluated using the oswestry disability index (ODI) and visual analogue scale (VAS) scores before and after treatment at 1, 3, 6, and 12 months and using the patient …

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Evaluation Of The Retinal Nerve Fiber Layer And Ganglion Cell Complex Thicknesses In Patients With Exfoliation Syndrome, Cem Alay, Oya Tekeli̇, Özge Yanik Odabaş, Feyza Çaliş Karanfi̇l Jan 2019

Evaluation Of The Retinal Nerve Fiber Layer And Ganglion Cell Complex Thicknesses In Patients With Exfoliation Syndrome, Cem Alay, Oya Tekeli̇, Özge Yanik Odabaş, Feyza Çaliş Karanfi̇l

Turkish Journal of Medical Sciences

Background/aim: This study aimed to evaluate retinal nerve fiber layer (RNFL) and ganglion cell complex (GCC) thicknesses using spectral domain optical coherence tomography (SD-OCT) in both unilateral and bilateral exfoliation syndrome (XFS) patients.Materials and methods: Twenty-four patients with unilateral XFS, 20 patients with bilateral XFS, and 23 healthy subjects were enrolled in this study. Eyes with XFS were compared with both fellow eyes and age-matched control subject eyes in terms of mean and segmental RNFL thickness and minimum, mean, and segmental GCC thickness. Results: In the bilateral XFS group, minimum GCC of the right eye (75.80 ± 11.6 μm) was …

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Risk Factors For Rectal Colonization Of Carbapenem-Resistant Enterobacteriaceae In A Tertiary Care Hospital: A Case-Control Study From Turkey, Fatma Eser, Gülruhsar Yilmaz, Hati̇ce Rahmet Güner, İmran Hasanoğlu, Fatma Yekta Ürkmez Korkmaz, Zi̇yaci̇bali̇ Açikgöz, Mehmet Akin Taşyaran Jan 2019

Risk Factors For Rectal Colonization Of Carbapenem-Resistant Enterobacteriaceae In A Tertiary Care Hospital: A Case-Control Study From Turkey, Fatma Eser, Gülruhsar Yilmaz, Hati̇ce Rahmet Güner, İmran Hasanoğlu, Fatma Yekta Ürkmez Korkmaz, Zi̇yaci̇bali̇ Açikgöz, Mehmet Akin Taşyaran

Turkish Journal of Medical Sciences

Background/aim: This study aimed to evaluate the risk factors of patients colonized with carbapenem-resistant Enterobacteriaceae (CRE).Materials and methods: The study was conducted between January 2010 and March 2016. The colonized group consisted of patients who had a CRE strain in their rectal swab cultures, whereas patients with negative rectal surveillance cultures for CRE who were concurrently hospitalized in the same units with the colonized group patients were included in the control group.Results: The number of patients in the colonized and the control group was 71 and 120, respectively. Both groups were evaluated for demographic and healthcare-associated characteristics. Isolated microorganisms in …

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Effects Of Ankaferd Hemostat On Helicobacter Pylori Strains And Antibiotic Resistance, Rafi̇ye Çi̇ftçi̇ler, Ahmet Koluman, İbrahi̇m Celaletti̇n Haznedaroğlu, Nejat Akar Jan 2019

Effects Of Ankaferd Hemostat On Helicobacter Pylori Strains And Antibiotic Resistance, Rafi̇ye Çi̇ftçi̇ler, Ahmet Koluman, İbrahi̇m Celaletti̇n Haznedaroğlu, Nejat Akar

Turkish Journal of Medical Sciences

Background/aim: Ankaferd hemostat (ABS; Ankaferd blood stopper, İstanbul, Turkey) is a folkloric medicinal plant extract. The aim of this study was to determine the effect of Ankaferd hemostat (ABS) on the fate of Helicobacter pylori strains. The study also aims to determine alterations in the antimicrobial resistance of three different H. pylori strains in response to ABS exposure.Materials and methods: H. pylori Strain 1 was obtained from the culture collection ATCC 43504 and passaged three times for viability. Strain 2 was isolated from a gastric ulcer patient and Strain 3 was isolated from a gastritis patient. 1% of ABS was …

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Factors Associated With Glomerular Filtration Rate Variation In Primary Hyperparathyroidism After Parathyroidectomy, Mustafa Çalişkan, Muhammed Kizilgül, Selvi̇han Beysel, Beki̇r Uçan, Fati̇h Alper Akcan, Mümtaz Takir, Mustafa Özbek, Erman Çakal Jan 2019

Factors Associated With Glomerular Filtration Rate Variation In Primary Hyperparathyroidism After Parathyroidectomy, Mustafa Çalişkan, Muhammed Kizilgül, Selvi̇han Beysel, Beki̇r Uçan, Fati̇h Alper Akcan, Mümtaz Takir, Mustafa Özbek, Erman Çakal

Turkish Journal of Medical Sciences

Background/aim: Prolonged hypercalcemia impairs renal function, and a reduced glomerular filtration rate (GFR) is typical in advanced primary hyperparathyroidism (PHPT). There are scarce data related to predictors of renal impairment in patients with PHPT. Hence, we aimed to evaluate changes in kidney function in PHPT patients after parathyroidectomy (PTX) and identify factors associated with GFR variation in these patients.Materials and methods: One hundred and twenty-five patients with PHPT who underwent surgery between 2012 and 2014 were enrolled in the study. Patients were divided into two groups according to GFR values: patients whose GFR was lower than 60 mL/min/1.73 m2 and …

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Anticandidal Activities Of Lactic Acid Bacteria Isolated From The Vagina, Sevda Er, Ayşe İstanbullu Tosun, Gi̇zem Arik Berk, Meri̇h Kivanç Jan 2019

Anticandidal Activities Of Lactic Acid Bacteria Isolated From The Vagina, Sevda Er, Ayşe İstanbullu Tosun, Gi̇zem Arik Berk, Meri̇h Kivanç

Turkish Journal of Medical Sciences

Background/aim: Lactic acid bacteria prevent the overgrowth of pathogenic agents and opportunistic pathogens in the vagina. Moreover, lactic acid bacteria contribute to the preservation of vaginal microbiota by producing antimicrobial agents. Previous studies showed that some lactic acid bacteria exhibited antimicrobial activity against Candida species causing yeast vaginosis as well as many bacterial pathogens.Materials and methods: The antifungal activities of various lactic acid bacteria isolated from the vagina of healthy women on some Candida species isolated from the vagina were investigated by agar diffusion technique. Results: Most of the lactic acid bacteria that belong to the species of Lactobacillus crispatus, …

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Serum Fetuin-A Is Associated With The Components Of Miac(Malnutrition, Inflammation, Atherosclerosis, Calcification) Syndrome In Different Stages, Rüya Mutluay, Ceyla Konca Değerteki̇n, Emel Işiktaş Sayilar, Ülver Deri̇ci̇, Serap Gülteki̇n, Sevi̇m Gönen, Seli̇m Turgay Arinsoy, Mahmut Şükrü Si̇ndel Jan 2019

Serum Fetuin-A Is Associated With The Components Of Miac(Malnutrition, Inflammation, Atherosclerosis, Calcification) Syndrome In Different Stages, Rüya Mutluay, Ceyla Konca Değerteki̇n, Emel Işiktaş Sayilar, Ülver Deri̇ci̇, Serap Gülteki̇n, Sevi̇m Gönen, Seli̇m Turgay Arinsoy, Mahmut Şükrü Si̇ndel

Turkish Journal of Medical Sciences

Background/aim: Fetuin-A, a circulating inhibitor of calcification, is a marker of inflammatory-nutritional state. We evaluated the association between serum fetuin-A levels and vascular calcification, intima-media thickness, and nutritional and inflammatory markers in different stages of chronic kidney disease (CKD). Materials and methods: CKD patients were sampled for calcium-phosphate parameters and nutritional and inflammatory markers [highly sensitive C-reactive protein (hs-CRP)], and serum fetuin-A levels. Intima-media thicknesses of the common carotid arteries (CIMT) were measured. Peripheral artery calcification scores were obtained.Results: A total of 238 patients were included in the study. Fetuin-A levels in patients with end-stage renal disease were significantly lower …

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S1pr2 Deficiency Enhances Neuropathic Pain Induced By Partial Sciatic Nerve Ligation, Qiang Gu, Jin Chao Hou, Xiang Ming Fang Jan 2019

S1pr2 Deficiency Enhances Neuropathic Pain Induced By Partial Sciatic Nerve Ligation, Qiang Gu, Jin Chao Hou, Xiang Ming Fang

Turkish Journal of Medical Sciences

Background/aim: Sphingosine 1-phosphate receptor 2 (S1PR2), a member of the seven-transmembrane receptor family, can be activated by its natural ligand sphingosine 1-phosphate (S1P) to initiate signal transduction and is involved in a wide range of biological effects such as immune cell migration and vascular permeability. Its relationship with neuropathic pain (NP) has not been reported. In this study, the effects of S1PR2 on the development of NP were studied.Materials and methods: We generated a model of NP by partial sciatic nerve ligation (pSNL). The 50% paw withdrawal threshold of the wild-type (WT) group and the S1PR2 deficiency group were measured …

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