Digital Commons Network^™

Do Judges Cry? An Essay On Empathy And Fellow-Feeling, Richard Delgado, Jean Stefancic

Case Western Reserve Law Review

No abstract provided.

The Content-Discrimination Principle And The Impact Of Reed V. Town Of Gilbert, David L. Hudson Jr.

Case Western Reserve Law Review

No abstract provided.

Securities & Exchange Commission Vs. Elon Musk & The First Amendment, Jerry W. Markham

Case Western Reserve Law Review

No abstract provided.

Measuring And Evaluating Directional Textures And Using Them In Visual Discovery, Manil Maskey

Dissertations

This dissertation focuses on three aspects of directional textures. The first aspect is the development of a new directional texture-based visualization technique to address challenges in visualizing multivariate data in a single display. The technique uses a multi level Markov Random Field-based texture synthesis to progressively generate a visualization that encodes data variables using various texture features, especially texture direction. Since texture directionality has not been used extensively in visualization, this technique provides a new visual cue to display additional data variable in a single display. Evaluations of the new texture-based visualization technique are also presented. The second aspect is …

Making “Meaningful Access” Even Less Meaningful: Judicial Gatekeeping Under Title Ii Of The Americans With Disabilities Act, Cheryl Anderson

University of Memphis Law Review

No abstract provided.

Making “Meaningful Access” Even Less Meaningful: Judicial Gatekeeping Under Title Ii Of The Americans With Disabilities Act, Cheryl Anderson

University of Memphis Law Review

No abstract provided.

Making “Meaningful Access” Even Less Meaningful: Judicial Gatekeeping Under Title Ii Of The Americans With Disabilities Act, Cheryl Anderson

University of Memphis Law Review

No abstract provided.

Volume 36 - Full Volume

National Forensic Journal

No abstract provided.

Hunter-Gatherers Harvested And Heated Microbial Biogenic Iron Oxides To Produce Rock Art Pigment, Brandi Lee Macdonald, David Stalla, Xiaoqing He

KIP Articles

Red mineral pigment use is recognized as a fundamental component of a series of traits associated with human evolutionary development, social interaction, and behavioral complexity. Iron-enriched mineral deposits have been collected and prepared as pigment for use in rock art, personal adornment, and mortuary practices for millennia, yet little is known about early developments in mineral processing techniques in North America. Microanalysis of rock art pigments from the North American Pacific Northwest reveals a sophisticated use of iron oxide produced by the biomineralizing bacterium Leptothrix ochracea; a keystone species of chemolithotroph recognized in recent advances in the development of thermostable, …

“A Secret Place Above The Trees”: Keatsian Imagination In Fitzgerald’S The Great Gatsby, Kate Lisowski

Masters Essays

No abstract provided.

Navigating Conflict: A Transcendental Phenomenological Study Of Online Higher Education Subject Matter Experts, Tammi Clearfield

Department of Conflict Resolution Studies Theses and Dissertations

This qualitative study, using phenomenology, examined the lived experiences of subject matter experts navigating conflict in the higher education online course development process. Examination of conflict from the perspective of the subject matter expert in this context was important because of impacts on subject matter experts, design and development team members, course quality, instructors, students, and institutions. Research questions that guided the study were: What were the potential sources of conflict encountered by the subject matter expert throughout the course development process? What did the conflict mean to the subject matter expert in the course development process? How did the …

Engineering Stem Cell Cardiac Patch With Microvascular Features Representative Of Native Myocardium, Zichen Qian, Dhavan Sharma, Wenkai Jia, Daniel Radke, Timothy Kamp, Feng Zhao

Michigan Tech Publications, Part 1

The natural myocardium is a highly aligned tissue with an oriented vasculature. Its characteristic cellular as well as nanoscale extracellular matrix (ECM) organization along with an oriented vascular network ensures appropriate blood supply and functional performance. Although significant efforts have been made to develop anisotropic cardiac structure, currently neither an ideal biomaterial nor an effective vascularization strategy to engineer oriented and high-density capillary-like microvessels has been achieved for clinical cardiovascular therapies. A naturally derived oriented ECM nanofibrous scaffold mimics the physiological structure and components of tissue ECM and guides neovascular network formation. The objective of this study was to create …

Automatic 13C Chemical Shift Reference Correction Of Protein Nmr Spectral Data Using Data Mining And Bayesian Statistical Modeling, Xi Chen

Theses and Dissertations--Molecular and Cellular Biochemistry

Nuclear magnetic resonance (NMR) is a highly versatile analytical technique for studying molecular configuration, conformation, and dynamics, especially of biomacromolecules such as proteins. However, due to the intrinsic properties of NMR experiments, results from the NMR instruments require a refencing step before the down-the-line analysis. Poor chemical shift referencing, especially for ¹³C in protein Nuclear Magnetic Resonance (NMR) experiments, fundamentally limits and even prevents effective study of biomacromolecules via NMR. There is no available method that can rereference carbon chemical shifts from protein NMR without secondary experimental information such as structure or resonance assignment.

To solve this problem, we …

City Limits: Heat Tolerance Is Influenced By Body Size And Hydration State In An Urban Ant Community, Dustin Jerald Johnson

University of the Pacific Theses and Dissertations

Cities are rapidly expanding, and global warming is intensified in urban environments due to the urban heat island effect. Therefore, urban animals may be particularly susceptible to warming associated with ongoing climate change. Thus, I used a comparative and manipulative approach to test three related hypotheses about the determinants of heat tolerance or critical thermal maximum (CTmax) in urban ants—specifically, that (1) body size, (2) hydration status, and (3) preferred micro-environments influence CTmax. I further tested a fourth hypothesis that native species are particularly physiologically vulnerable in urban environments. I manipulated water access and determined CTmax for 11 species common …

Immunological Pathways Triggered By Porphyromonas Gingivalis And Fusobacterium Nucleatum: Therapeutic Possibilities?, Kívia Queiroz De Andrade, Cassio Luiz Coutinho Almeida-Da-Silva, Robson Coutinho-Silva

All Dugoni School of Dentistry Faculty Articles

Porphyromonas gingivalis (P. gingivalis) and Fusobacterium nucleatum (F. nucleatum) are Gram-negative anaerobic bacteria possessing several virulence factors that make them potential pathogens associated with periodontal disease. Periodontal diseases are chronic inflammatory diseases of the oral cavity, including gingivitis and periodontitis. Periodontitis can lead to tooth loss and is considered one of the most prevalent diseases worldwide. P. gingivalis and F. nucleatum possess virulence factors that allow them to survive in hostile environments by selectively modulating the host's immune-inflammatory response, thereby creating major challenges to host cell survival. Studies have demonstrated that bacterial infection and the host immune responses are involved …

The Evolution Of Sunset Magazine's Cooking Department: The Accommodation Of Men's And Women's Cooking In The 1930s, Jennifer Hoolhorst Pagano

University of the Pacific Theses and Dissertations

The Western regional magazine Sunset has been published under a series of owners and publishers since 1898. In 1928, Sunset was purchased by Lawrence Lane, a Midwestern magazine executive who transformed it from a failing turn-of-the-century, general interest publication about the West, into a successful magazine about living in the West for the Western middle-class. Sunset had always been a magazine for men and women, and one that appealed to both male and female intellectuals at the time Lane purchased it. Lane and his editors attempted to interject more rigid middle-class ideals into a magazine that had espoused ideas that …

Computer And Information Technology Major, Mathematics & Computer Science

Program Revisions/Additions

No abstract provided.

Due Process And The Myth Of Sovereignty, Michael Vitiello

McGeorge School of Law Scholarly Articles

No abstract provided.

Developmental Expression Of Monocarboxylate Transporter 1 And 4 In Rat Liver, Michael Ng, Justin Louie, Jieyun Cao, Melanie A. Felmlee

School of Pharmacy Faculty Articles

PURPOSE: Monocarboxylate transporters (MCT) are proton-coupled integral membrane proteins that control the influx and efflux of endogenous monocarboxylates such as lactate, acetate and pyruvate. They also transport and mediate the clearance of drugs such as valproate and gamma-hydroxybutyrate. CD147 functions as ancillary protein that chaperones MCT1 and MCT4 to the cell membrane. There is limited data on the maturation of MCT and CD147 expression in tissues related to drug distribution and clearance. The objective of the present study was to quantify hepatic MCT1, MCT4, and CD147 mRNA, whole cell and membrane protein expression from birth to sexual maturity.

METHODS: Liver …

Mechanisms Underlying Neuroprotection By The Nsaid Mefenamic Acid In An Experimental Model Of Stroke, Parto S. Khansari, Robert F. Halliwell

School of Pharmacy Faculty Articles

Stroke is a devastating neurological event with limited treatment opportunities. Recent advances in understanding the underlying pathogenesis of cerebral ischemia support the involvement of multiple biochemical pathways in the development of the ischemic damage. Fenamates are classical non-steroidal anti-inflammatory drugs but they are also highly subunit-selective modulators of GABAA receptors, activators of IKS potassium channels and antagonists of non-selective cation channels and the NLRP3 inflammosome. In the present study we investigated the effect of mefenamic acid (MFA) in a rodent model of ischemic stroke and then addressed the underlying pharmacological mechanisms in vitro for its actions in vivo. The efficacy …

The Influence Of Food Insecurity, Low-Income, And Race On Diabetes Self-Management Practices Among Women With Diabetes, Jill La Capria

Walden Dissertations and Doctoral Studies

Diabetes is a chronic condition affecting more than 30 million adults living in the United States. Diabetes self-management (DSM) can prevent or delay the complications of diabetes and improve clinical outcomes; however, data show that low-income, food insecurity, female gender, and race contribute to challenges performing effective DSM. The health belief model was the theoretical framework for this cross-sectional study, which examined how food insecurity, low-income, and race affect DSM activities in women with diabetes. The sample population from the 2017 Behavioral Risk Factor Surveillance System survey consisted of 1,842 women with diabetes who were 18 years of age or …

The Digital Public Humanities: Giving New Arguments And New Ways To Argue, Jordana Cox, Lauren Tilton

Rhetoric and Communication Studies Faculty Publications

In response to the latest "crisis" in the humanities, advocates have marched, rallied, fundraised, and-especially-argued. This essay contends that communication scholars can support the growing "case for the humanities" by analyzing argumentative strategies, and more specifically, by offering ethical argumentative strategies that avoid replicating structures of domination. In particular, we look to Mari Lee Mifsud's theorization of rhetoric as gift, which follows Henry W. Johnstone in conceptualizing argument as something other than winning over an adversary. We place Mifsud's theorization of the gift in conversation with the methods of the digital public humanities (DPH), which acknowledge and offer abundant resources …

Rural Business Development Corporation Annual Report 2019, Department Of Primary Industries And Regional Development, Western Australia

All other publications

In accordance with section 63 of the Financial Management Act 2006, we hereby submit for your information and presentation to Parliament, the annual report of the Rural Business Development Corporation for the reporting period ended 30 June 2019.

The annual report has been prepared in accordance with the provisions of the Financial Management Act 2006 and the Rural Business Development Corporation Act 2000.

Digital Media, Technology

Program Revisions/Additions

No abstract provided.

Media Technology Minor, Technology

Program Revisions/Additions

No abstract provided.

Effect Of Manipulation Of Notch Signaling Pathway On Neural Stem Cell Proliferation In The Hippocampus Following Traumatic Brain Injury, Seung L. Kim

Theses and Dissertations

Effect of Manipulation of Notch Signaling Pathway on Neural Stem Cell Proliferation in the Hippocampus Following Traumatic Brain Injury

By Seung L. Kim A thesis statement submitted for degree requirement in Mater of Science Virginia Commonwealth University, 2019 Advisor: Dong Sun, MD. PhD. Department of Anatomy & Neurobiology

The Notch signaling pathway is known as a core signaling system in maintaining neural stem cells (NSCs) in embryonic development and adulthood including cell proliferation, maturation, and cell fate decision. Proliferation of NSCs persists throughout lifespan in neurogenic niches and is often upregulated following neurological insults including traumatic brain injury (TBI). Therefore, …

The Effect Of Repeated Opioid Dosing On The Gut Microbiome, Anne K. Rowe

Theses and Dissertations

Opioids are prescribed to millions of people each year, especially to help patients cope with chronic pain, something from which more than a fifth of U.S. adults suffer (CDC). Unfortunately, opioid use and abuse has become a national emergency as the number of opioid prescriptions, opioid misuse, and opioid-related drug overdoses and death have drastically increased in the last twenty years (HHS). Because of the emergent state surrounding opioid use and misuse, the effects of opioids on all aspects of the human body has been an increasingly large focus of research scientists. This study focuses on the possible effect of …

The Nail That Sticks Up Isn't Always Hammered Down: Women, Employment Discrimination, And Litigiousness In Japan, Kristen Luck

Theses and Dissertations

Much recent scholarship is devoted to projecting Japan’s future and analyzing its prospects as a global power. After two decades of economic stagnation, alarming demographic trends, and the 3/11 triple disaster, some scholars argue that Japan is grappling with an era of precarity, marked with instability and anxiety. Prime Minister Shinzo Abe returned to office in 2012, promoting his economic reform policy, “Abenomics” and within the third “arrow" of this approach targeting structural reforms, he promoted “womenomics”, a term coined by Kathy Matsui of Goldman-Sachs. Prime Minister Abe’s objective is to create a society where "women can shine” and women …

A Novel Framework For Social Internet Of Things: Leveraging The Friendships And The Services Exchanged Between Smart Devices, Javad Abed

Theses and Dissertations

As humans, we tackle many problems in complex societies and manage the complexities of networked social systems. Cognition and sociability are two vital human capabilities that improve social life and complex social interactions. Adding these features to smart devices makes them capable of managing complex and networked Internet of Things (IoT) settings.

Cognitive and social devices can improve their relationships and connections with other devices and people to better serve human needs. Nowadays, researchers are investigating two future generations of IoT: social IoT (SIoT) and cognitive IoT (CIoT). This study develops a new framework for IoT, called CSIoT, by using …

Geospatial Analysis Of Invasive Plant Species And Their Threats To Ecological Functionality At The Vcu Rice Rivers Center, Erik W. Kellogg

Theses and Dissertations

Invasive plants are a significant threat to native ecosystems and to biodiversity. They are often strong competitors and have multiple techniques to outcompete native plants. Thus, controlling or removing invasive plants facilitates the restoration of native ecosystems. We used GPS technology coupled with field surveying techniques adapted from the U.S. Fish and Wildlife Service to locate and identify invasive plants present within VCU’s Rice Rivers Center. We digitally overlaid a 50-meter x 50-meter grid system over the property. In each grid cell we recorded visual estimations of invasive plant coverage sorted into modified Daubenmire cover classes and used ArcGIS for …