Digital Commons Network^™

Effects Of Secondary Stall And Unsteady Free-Stream On Blade Drag And Pitching Moments, Michael Malick

McKelvey School of Engineering Graduate Student Theses & Dissertations

Dynamic stall is a complex aerodynamic phenomenon occurring in helicopter rotors, limiting the flight envelope and causing control linkage damage and instabilities. The Peters-Modarres semi-empirical dynamic stall model is extended to simulate pitching moment and drag in unsteady freestream and yawed flow, including the effects of secondary stall. The aerodynamics are implemented as a state-space model, suitable for time-marching or aeroelastic analyses. With small modifications to the original stall model, secondary stall effects and unsteady freestream can be simulated without adding additional states. An optimization routine determines sets of parameters that minimize the error between the modeled solution and experimental …

Kcnq1/Kcne1 Interaction In The Cardiac Iks Channel And Its Physiological Consequences, Jiajing Xu

McKelvey School of Engineering Graduate Student Theses & Dissertations

Dynamic conformational changes of ion channel proteins during activation gating determine their function as carriers of current. The relationship between these molecular movements and channel function over the physiological timescale of the action potential (AP) has not been fully established due to limitations of existing techniques. We constructed a library of possible cardiac IKs protein conformations and applied a combination of protein segmentation and energy linearization to study this relationship computationally. Simulations reproduced the effects of the beta-subunit (KCNE1) on the alpha-subunit (KCNQ1) dynamics and function, observed in experiments. Mechanistically, KCNE1 increased the probability of “visiting” conducting pore conformations on …

Graphene Oxides In Water: Characterization, Reactivity, And Application, Siyuan An

McKelvey School of Engineering Graduate Student Theses & Dissertations

Recently discovered, graphene and graphene oxide materials have drawn considerable research attention due to outstanding and novel properties, which underpin wide material potential for a number of advanced applications including supercapacitors, solar cells, sensors, catalysts, semiconductors, sorbents, and membranes, among others. Graphene oxides (GO), which are considered as a family of oxidized graphene materials (derivatives), is a key precursor to the synthesis of free-standing graphene via oxidation-exfoliation-reduction pathways. GO properties depend on the synthesis routes/conditions (i.e. derivatization), including partially maintaining graphene (i.e. sp2) properties. Further, oxygen-containing functionalities (epoxy, hydroxyl, carbonyl, and carboxyl groups) render GO hydrophilic – and correspondingly stability …

Investigating Cyanobacteria Metabolism And Channeling-Based Regulations Via Isotopic Nonstationary Labeling And Metabolomic Analyses, Mary Helen Abernathy

McKelvey School of Engineering Graduate Student Theses & Dissertations

Cyanobacteria have the potential to be low-cost and sustainable cell factories for bio-products; however, many challenges face cyanobacteria as biorefineries. This dissertation seeks to advance non-model photosynthetic organisms for biotechnology applications by characterizing central carbon metabolism and its regulations. Cyanobacteria phenotypes for bio-production are examined and their intracellular metabolism is quantified. Using isotopic labeling experiments, phenotypic relationships between biomass composition, central carbon fluxes, and metabolite pool sizes are investigated. Metabolic analyses of cyanobacteria led to new investigations of flux regulation mechanisms via protein spatial organizations or metabolite channeling. Metabolite channeling is further explored as a hypothesis to explain enigmatic labeling …

Multifunctional Nanocomposites Based On Bacterial Cellulose, Qisheng Jiang

McKelvey School of Engineering Graduate Student Theses & Dissertations

Cellulose is biodegradable, renewable, and abundant in nature thus cellulose (or paper)-based products can be inexpensively produced and recycled. Among cellulosic materials, bacterial nanocellulose (BNC) draws a special research attention due to the inherent three-dimensional nanofibrous structure, excellent mechanical flexibility, high purity and well-defined surface chemistry, and cost-efficient, scalable and environment-friendly synthesis. BNC can be biosynthesized by Gluconacetobacter xylinus, which is the most characterized BNC producer among various microorganisms. BNC is composed of highly pure cellulose nanofibrils, produced from well-defined dextrose through biochemical steps and subsequent self-assembling of the secreted cellulose fibrils which has the dimension ranges from 25 to …

Development Of The Emotional Verbal Learning Test - Spanish (Evlt-S), Davor Nicolas Zink

UNLV Theses, Dissertations, Professional Papers, and Capstones

Emotional disturbances are common features of clinical disorders and are often present in individuals who have neurodevelopmental or acquired brain disorders. The Hispanic population is the largest and fastest growing ethnic minority group in the United States (U.S.) and by 2050 is projected to be the largest. However, few instruments are available to evaluate emotional functioning in individuals who speak Spanish. Fewer still are available to assess cognitive disturbances resulting from brain dysfunction that impact emotion processing. Normal processing of emotion is critical for social functioning. In recent years it has become apparent that cognitive abilities specialized to process social …

Efficient And Practical Composition Of Lock-Free Data Structures, Neha Bajracharya

UNLV Theses, Dissertations, Professional Papers, and Capstones

A concurrent data object is lock-free if it guarantees that at least one, among all concurrent operations, finishes after a finite number of steps. In other words, a lock free technique guarantees that some thread always makes progress. Lock-free data objects offer several advantages over their blocking counterparts, such as being immune to deadlocks and priority inversion, and typically provide high scalability and performance, especially in shared memory multiprocessor architectures.

Composition of data structures is a powerful approach to combine simple data structures to create more complex ones. It works as a building block for many advanced useful data structures. …

Performance-Based Economical Seismic Design Of Multistory Reinforced Concrete Frame Buildings And Reliability Assessment, Chunyu Zhang

UNLV Theses, Dissertations, Professional Papers, and Capstones

As the next generation of seismic design methodology, performance-based seismic design (PBSD) method requires a structure satisfy multiple preselected performance levels under different hazard levels. Optimal PBSD methods provide different strategies to design the numerous variables, including strength, stiffness and ductility of each structural component. The overall goal of this study is to develop a new optimal PBSD method for multi-story RC moment frames. This method is capable of overcoming the deficiencies of existing optimal PBSD methods and can be implemented by the U.S. design practice. The proposed method minimizes construction cost and takes the limit of member plastic rotation …

Combinatorial Ant Optimization And The Flowshop Problem, Tasmin Chowdhury

UNLV Theses, Dissertations, Professional Papers, and Capstones

Researchers have developed efficient techniques, meta-heuristics to solve many Combinatorial Optimization (CO) problems, e.g., Flow shop Scheduling Problem, Travelling Salesman Problem (TSP) since the early 60s of the last century. Ant Colony Optimization (ACO) and its variants were introduced by Dorigo et al. [DBS06] in the early 1990s which is a technique to solve CO problems. In this thesis, we used the ACO technique to find solutions to the classic Flow shop Scheduling Problem and proposed a novel method for solution improvement. Our solution is composed of two phases; in the first phase, we solved TSP using ACO technique which …

A Distributed Real-Time Short-Term Solar Irradiation Forecasting Network For Photovoltaic Systems, Michael Adelbert Gacusan

UNLV Theses, Dissertations, Professional Papers, and Capstones

Solar irradiation forecasting is essential for PV connected electrical grids to maintain reliability, stability, and effective matching of real-time demand to power distribution. This research paper develops and evaluates proposed forecasting methods using wireless sensor networks. Each node of the network is capable of monitoring illuminance data and communicate it through RF and/or WiFi. The nodes are calibrated with respect to irradiance data from an industry-standard pyranometer. Power consumption of each node type is also collected at different operating states. The proposed sensor network can estimate a cloud motion vector or a cloud shadow’s speed and direction from the data …

Measuring Housing And Population Densities In Dublin City & County, Paul J. Lawlor Mr, Max Mcgovern, Hugo Fitzpatrick, Carl Wessels

Articles

A key strategic objective of Irelands national land use plan (known as the National Planning Framework) is to accommodate a significant increase in population in Irish cities in more concentrated settlement patterns and at higher residential densities. This is to be achieved by requiring 50% of new residential developments to be located in infill and brownfield locations in cities such as Dublin. This paper explores the implications of this policy by examining existing housing and population density in Dublin using CSO data and mapping tools to measure densities throughout the City and County. A ranking of areas with the highest …

Molecular Basis Of Class Ib Drug Interactions With The Nav Channel Macromolecular Complex: A Route To Personalized Medicine For Cardiac Arrhythmia, Wandi Zhu

McKelvey School of Engineering Graduate Student Theses & Dissertations

The heart rhythm is precisely controlled by the electrical impulse that propagate in the cardiac tissue. In single cardiomyocytes, the electrical activity generated by action potentials (AP). Cardiac NaV channels (NaV1.5) carry a large influx of Na+ that mediates the initiation and propagation of the AP in both atria and ventricles. Disruption of NaV1.5 function by genetic variants or external factors can result in deadly arrhythmias, such as long QT syndrome and Brugada syndrome. Thus, NaV channels are import therapeutic targets. The class I antiarrhythmics are the modulators of the NaV channels. Although they have been used clinically for over …

Computational Explorations Of Information And Mechanism Design In Markets, Zhuoshu Li

McKelvey School of Engineering Graduate Student Theses & Dissertations

Markets or platforms assemble multiple selfishly-motivated and strategic agents. The outcomes of such agent interactions depend heavily on the rules, regulations, and norms of the platform, as well as the information available to agents. This thesis investigates the design and analysis of mechanisms and information structures through the ``computational lens'' in both static and dynamic settings. It both addresses the outcome of single platforms and fills a gap in the study of the dynamics of multiple platform interactions.

In static market settings, we are particularly interested in the role of information, because mechanisms are harder to change than the information …

Learning About Large Scale Image Search: Lessons From Global Scale Hotel Recognition To Fight Sex Trafficking, Abby Stylianou

McKelvey School of Engineering Graduate Student Theses & Dissertations

Hotel recognition is a sub-domain of scene recognition that involves determining what hotel is seen in a photograph taken in a hotel. The hotel recognition task is a challenging computer vision task due to the properties of hotel rooms, including low visual similarity between rooms in the same hotel and high visual similarity between rooms in different hotels, particularly those from the same chain. Building accurate approaches for hotel recognition is important to investigations of human trafficking. Images of human trafficking victims are often shared by traffickers among criminal networks and posted in online advertisements. These images are often taken …

Basis Vector Model Method For Proton Stopping Power Estimation Using Dual-Energy Computed Tomography, Shuangyue Zhang

McKelvey School of Engineering Graduate Student Theses & Dissertations

Accurate estimation of the proton stopping power ratio (SPR) is important for treatment planning and dose prediction for proton beam therapy. The state-of-the-art clinical practice for estimating patient-specific SPR distributions is the stoichiometric calibration method using single-energy computed tomography (SECT) images, which in principle may introduce large intrinsic uncertainties into estimation results. One major factor that limits the performance of SECT-based methods is the Hounsfield unit (HU) degeneracy in the presence of tissue composition variations. Dual-energy computed tomography (DECT) has shown the potential of reducing uncertainties in proton SPR prediction via scanning the patient with two different source energy spectra. …

Biosensing By “Growing” Antennas And Error-Correcting Codes, Mingquan Yuan

McKelvey School of Engineering Graduate Student Theses & Dissertations

Food-borne disease outbreaks not only cause numerous fatalities every year but also contribute to significant economic losses. While end-to-end supply chain monitoring can be one of the keys to preventing these outbreaks, screening every food product in the supply chain is not feasible considering the sheer volume and prohibitive test costs. Fortunately, two converging economic trends promise to make this end-to-end supply chain monitoring possible. The first trend is that passive radio-frequency identification (RFID) tags and quick response (QR) codes are now widely accepted for food packaging. The second trend is that smartphones are now equipped with the capability to …

Towards Engineering Advanced Nanomaterials: Elucidating Fundamental Particle Behavior In Water And Critical Sorption Dynamics, Changwoo Kim

McKelvey School of Engineering Graduate Student Theses & Dissertations

As advanced nanomaterials, inorganic-organic nano composites have received great interest as potential platform (nano) structures for sensor, catalyst, sorbent, and environmental applications. Here, my Ph.D. research has focused on the design, synthesis, and characterization of advanced water-stable engineered metal-oxide nanoparticles functionalized by organic frames for environmental applications. For the environmental applications, I have evaluated particleoptimized sorption processes for the remediation and separation of arsenic, chromium, and uranium under environmentally relevant conditions. More specifically, I have explored the critical role of organic coating on sorption mechanisms and performances using engineered iron oxide -based, manganese oxide -based, and manganese ferrite -based (core) …

Nanopower Analog Frontends For Cyber-Physical Systems, Kenji Aono

McKelvey School of Engineering Graduate Student Theses & Dissertations

In a world that is increasingly dominated by advances made in digital systems, this work will explore the exploiting of naturally occurring physical phenomena to pave the way towards a self-powered sensor for Cyber-Physical Systems (CPS). In general, a sensor frontend can be broken up into a handful of basic stages: transduction, filtering, energy conversion, measurement, and interfacing. One analog artifact that was investigated for filtering was the physical phenomenon of hysteresis induced in current-mode biquads driven near or at their saturation limit. Known as jump resonance, this analog construct facilitates a higher quality factor to be brought about without …

Effects Of Secondary Stall And Unsteady Free-Stream On Blade Drag And Pitching Moments, Michael Malick

McKelvey School of Engineering Graduate Student Theses & Dissertations

Dynamic stall is a complex aerodynamic phenomenon occurring in helicopter rotors, limiting the flight envelope and causing control linkage damage and instabilities. The Peters-Modarres semi-empirical dynamic stall model is extended to simulate pitching moment and drag in unsteady freestream and yawed flow, including the effects of secondary stall. The aerodynamics are implemented as a state-space model, suitable for time-marching or aeroelastic analyses. With small modifications to the original stall model, secondary stall effects and unsteady freestream can be simulated without adding additional states. An optimization routine determines sets of parameters that minimize the error between the modeled solution and experimental …

Mechanisms Of Calcium Phosphate Mineralization On Biological Interfaces And Their Engineering Applications, Doyoon Kim

McKelvey School of Engineering Graduate Student Theses & Dissertations

All living organisms utilize phosphorus (P) as an essential component of their cell membranes, DNA and RNA, and adenosine triphosphate. Bones, in addition to bearing loads, play an important role in balancing P levels in our bodies. In bones, a network of collagen templates and calcium phosphate (CaP) nanocrystals builds hierarchical levels, from nano- to macroscale. Within this architecture, the thermodynamic properties of CaP minerals are influential. Despite the importance of nucleation, growth, and crystallization in collagen structures for tissue development, little kinetic study of these processes has been conducted due to the limited in situ techniques for monitoring these …

Multifunctional Nanocomposites Based On Bacterial Cellulose, Qisheng Jiang

McKelvey School of Engineering Graduate Student Theses & Dissertations

Cellulose is biodegradable, renewable, and abundant in nature thus cellulose (or paper)-based products can be inexpensively produced and recycled. Among cellulosic materials, bacterial nanocellulose (BNC) draws a special research attention due to the inherent three-dimensional nanofibrous structure, excellent mechanical flexibility, high purity and well-defined surface chemistry, and cost-efficient, scalable and environment-friendly synthesis. BNC can be biosynthesized by Gluconacetobacter xylinus, which is the most characterized BNC producer among various microorganisms. BNC is composed of highly pure cellulose nanofibrils, produced from well-defined dextrose through biochemical steps and subsequent self-assembling of the secreted cellulose fibrils which has the dimension ranges from 25 to …

Understanding Adolescent Physical Activity In The Early Nutrition Transitioning Country Of Haiti, Haley V. Becker

Arts & Sciences Graduate Student Theses and Dissertations

The nutrition transition is underway in Haiti, giving rise to the dual burden of malnutrition. Physical activity (PA) plays an important role in mitigating the negative health consequences of nutrition transition and the dual burden, but heretofore this data has been unavailable for Haiti. This dissertation undertook an exploratory needs assessment providing baseline PA data for Haitian adolescents. It evaluated two different PA data collection methodologies: a cross-sectional survey adapted from the IPAQ long-form and objectively measured PA via Actigraph GT1M accelerometers. Next, it identified initial covariates of self-reported and objectively-assessed PA behaviors; data was operationalized as meeting the World …

Freezing Of Gait: Mechanisms, Mechanics, And Management, Peter S. Myers

Arts & Sciences Graduate Student Theses and Dissertations

Parkinson disease (PD) is a neurodegenerative disease with multiple motor and non-motor symptoms, including postural instability, gait impairments, and cognitive deficits. More than 50% of individuals with PD experience a symptom called freezing of gait (FOG), described as a transient inability to take another step forward. Individuals with PD who experience FOG (freezers) have further postural, gait, and cognitive impairments compared to individuals with PD without FOG (non-freezers). While degeneration of the dopaminergic neurons in the substantia nigra is accepted as the primary etiology of the disease, research shows that the disease has a global impact on the brain, accounting …

Intersecting Variables Of Second And Foreign Language Reading: Self-Assessment And Comprehension With Adolescents And Adults Across Languages, Haley Dolosic

Arts & Sciences Graduate Student Theses and Dissertations

Today, more individuals are seeking to learn a second language (L2) or foreign language (FL) than ever before. These individuals are language learners who intend to use their growing L2 knowledge to traverse linguistic and national boundaries in order to achieve their personal and professional goals (Callahan & Gándara, 2014). To realize these goals in the digital era, L2 learners must be more prepared than ever to use their knowledge with written media, making L2 reading a central skill to successful use of their L2 knowledge. Yet, when language learners attempt to use their L2 skills in their daily lives, …

Decoding Complexity In Metabolic Networks Using Integrated Mechanistic And Machine Learning Approaches, Tolutola Timothy Oyetunde

McKelvey School of Engineering Graduate Student Theses & Dissertations

How can we get living cells to do what we want? What do they actually ‘want’? What ‘rules’ do they observe? How can we better understand and manipulate them? Answers to fundamental research questions like these are critical to overcoming bottlenecks in metabolic engineering and optimizing heterologous pathways for synthetic biology applications. Unfortunately, biological systems are too complex to be completely described by physicochemical modeling alone.

In this research, I developed and applied integrated mechanistic and data-driven frameworks to help uncover the mysteries of cellular regulation and control. These tools provide a computational framework for seeking answers to pertinent biological …

Ming China As A Gunpowder Empire: Military Technology, Politics, And Fiscal Administration, 1350-1620, Weicong Duan

Arts & Sciences Graduate Student Theses and Dissertations

This dissertation explores the transformation of Ming China in the gunpowder age. Focusing on the relation between military technology, politics, and fiscal administration, it closely traces the change of the Ming state in association with the gunpowder revolution. Two aspects of institutional change receive special attention. The first aspect is the formation of an absolute authority in the Ming period, a development exhibiting many parallels with the absolute monarchies of other major gunpowder states in Europe and the Islamic world. The second is the modification of the Confucian bureaucratic government. The revolutions in gunpowder technology had a complex impact on …

Using Design Science Research To Develop A Conceptual Solution For Improving Knowledge Sharing In A Virtual Workspace, Lata Koneru

UNLV Theses, Dissertations, Professional Papers, and Capstones

Enhancements in technology have resulted in significant changes to day-to-day operations of organizations in the present day. One especially noteworthy change is the alteration in the nature of teams from being co-located, with face-to-face interaction, to virtual, with the involvement of information and communication technologies (ICT) to facilitate communication. This change in team character has had a downstream impact on a key element of an organization’s competitive edge, namely knowledge.

Overall, there is consensus that knowledge is a crucial facet of the competitive edge of an organization. Consequently, knowledge management, knowledge sharing, and organizational learning are essential components of an …

Fluid Structure Interaction Study Of The Obstructive Sleep Apnea And Surgical Treatment Using Suture-Patch Device On The Patient’S Tongue, Yang Liu

UNLV Theses, Dissertations, Professional Papers, and Capstones

Up to 14% of the U.S. population is estimated to have obstructive sleep apnea (OSA) related to obesity, and there is increased incidence occurring worldwide. While treatment with continuous positive airway pressure (CPAP) resolves airway obstruction, patient compliance is relatively low. Alternative interventions are available to treat OSA patients; however, their outcomes have had variable results. For example, current technologies have demonstrated an inability to define and treat the specific anatomical site(s) causing the obstruction, resulting in suboptimal modifications of the airway and poor control of OSA.

In the current study, a three-dimensional (3-D) fluid-structure interaction (FSI) numerical simulation has …

Variable Transition Time Inverters In A Digital Delay Line With Analog Storage For Processing Fast Signals And Pulses, James Kenton Mellott

UNLV Theses, Dissertations, Professional Papers, and Capstones

As the electronics industry moves forward there is an increasing need to process information faster and more accurately. High speed signals are used in scientific instrumentation, range finding devices, radar applications, and electro-optical interfaces. High-speed state of the art analog-to-digital converters are required to process these signals in real time. High frequency signals or very fast pulses are not able to be processed accurately due to either Nyquist-rate limitations or practical power consumption limits. For applications where signals are transient in nature and design size and power consumption are major factors, the proposed Variable Fast Transient Digitizer (VFTD) will be …

Community College Students’ Perceptions Of Their Academic Workload, William Neff

UNLV Theses, Dissertations, Professional Papers, and Capstones

One major barrier to success, for first-time, full-time college students, is course workload (Bowyer, 2012). How students respond to their situation and the barriers they face may influence decisions they make about classes in which they should enroll or those they should avoid, completing or dropping a class during the semester, and persisting from term-to-term and year-to-year. In an effort to help students succeed, colleges often give them a specified set of core courses and a specific or even prescribed pathway to complete the “general education” requirements. These core courses such as mathematics, communication, and English, among others, taken separately …