Digital Commons Network^™

Provenance And Risk In Transfer Of Biological Materials, Jane Nielsen, Tania M. Bubela, Don R C. Chalmers, Amber Johns, Linda Kahl, Joanne Kamens, Charles Lawson, John Liddicoat, Rebekah Mcwhirter, Ann Monott

Office of the Provost

Whereas biological materials were once transferred freely, there has been a marked shift in the formalisation of exchanges involving these materials, primarily through the use of Material Transfer Agreements (MTAs). This paper considers how risk aversion dominates MTA negotiations and the impact it may have on scientific progress. Risk aversion is often based on unwarranted fears of incurring liability through the use of a material or loss of control or missing out on commercialisation opportunities. Evidence to date has suggested that complexity tends to permeate even straightforward transactions despite extensive efforts to implement simple, standard MTAs. We argue that in …

Genomic Analysis Of Acropora Cervicornis Mucus And Sediments In The Florida Keys Tavernier Nursery, Rachel Zimmerman

HCNSO Student Theses and Dissertations

White Band disease has devastated the staghorn coral Acropora cervicornis in recent decades, and it continues to impinge upon restoration efforts. The etiological agent(s) remain unknown as Koch’s postulates have yet to be satisfied, but disease may originate when opportunistic pathogens in the surface mucus layer exploit a stressed host. Using 16s rRNA sequencing, differences in the taxonomic diversity and relative abundances of bacteria within the mucus of A. cervicornis were documented between colonies of the same genotype, genotypes (n=8) categorized as having either high or low WBD susceptibility, and during a transplantation event. A. cervicornis colonies suspended from midwater …

Determining Relative Dynamic Stability Of Cell States Using Boolean Network Model., Jae Il Joo, Joseph X Zhou, Sui Huang, Kwang-Hyun Cho

Articles, Abstracts, and Reports

Cell state transition is at the core of biological processes in metazoan, which includes cell differentiation, epithelial-to-mesenchymal transition (EMT) and cell reprogramming. In these cases, it is important to understand the molecular mechanism of cellular stability and how the transitions happen between different cell states, which is controlled by a gene regulatory network (GRN) hard-wired in the genome. Here we use Boolean modeling of GRN to study the cell state transition of EMT and systematically compare four available methods to calculate the cellular stability of three cell states in EMT in both normal and genetically mutated cases. The results produced …

Topp, William Oral History Interview, Doris Meyer

Emeriti Society Oral History Collection

Professor of Computer of Mathematics and Computer Science (1970-2014). Topics include: Math Department in the 70's changes emphasis - theoretical to applied; Department responses to student demands and corporate need for computer training; Computer science and computer engineering degree programs established by the University; Department of Computer Science with fully accredited degree programs established by the University; Computer enrollment and programs flourish in the boom period of the 90's; Computer faculty and programs become part of the newly formed School of Engineering and Computer Science; The years faculty members Bill Topp and Bill Ford published assembly language and data structures …

Poultry Slaughterhouse Wastewater Treatment Using Submerged Fibers In An Attached Growth Sequential Batch Reactor, Hamidi Abdul Aziz, Nur Nasuha Ahmad Puat, Motasem Y.D. Alazaiza, Yung-Tse Hung

Civil and Environmental Engineering Faculty Publications

In this study, a sequential batch reactor (SBR) with different types of fibers was employed for the treatment of poultry slaughterhouse wastewater. Three types of fibers, namely, juite fiber (JF), bio-fringe fiber (BF), and siliconised conjugated polyester fiber (SCPF), were used. Four SBR experiments were conducted, using the fibers in different reactors, while the fourth reactor used a combination of these fibers. The treatment efficiency of the different reactors with and without fibers on biochemical oxygen demand (BOD), chemical oxygen demand (COD), ammonia-nitrogen (NH₃-N), phosphorus (P), nitrite (NO₂), nitrate (NO₃), total suspended solids (TSS), and oil-grease were evaluated. The removal …

The Tick Endosymbiont Candidatus Midichloria Mitochondrii And Selenoproteins Are Essential For The Growth Of Rickettsia Parkeri In The Gulf Coast Tick Vector, Khemraj Budachetri, Deepak Kumar, Gary Crispell, Christine Beck, Gregory Dasch, Shahid Karim

Faculty Publications

Background

Pathogen colonization inside tick tissues is a significant aspect of the overall competence of a vector. Amblyomma maculatum is a competent vector of the spotted fever group rickettsiae, Rickettsia parkeri. When R. parkeri colonizes its tick host, it has the opportunity to dynamically interact with not just its host but with the endosymbionts living within it, and this enables it to modulate the tick’s defenses by regulating tick gene expression. The microbiome in A. maculatum is dominated by two endosymbiont microbes: a Francisella-like endosymbiont (FLE) and CandidatusMidichloria mitochondrii (CMM). A range of selenium-containing proteins (selenoproteins) in A. …

Students Excell In Stem With Unh Manchester Summer Program Focused On Esol, Carol Robidoux

UNH Today Archive

No abstract provided.

Novel Stat3 Gene Mutation Related Hyper-Ige Syndrome Misdiagnosed As Hidradenitis Suppurativa., Pragya Shrestha, Geetika Sabharwal, Gisoo Ghaffari

Reading Hospital Internal Medicine Residency

Although Hyper-IgE Syndrome (HIES) is a rare immunodeficiency disorder, presenting symptoms may be as common as lung and skin infections. Symptoms are usually nonspecific such as recurrent abscesses, folliculitis, and pneumonias along with skeletal abnormalities. Careful history of susceptibility to skin and lung infections, thorough family history, and findings on physical exam can guide towards the diagnosis of this often-eluded condition. Early optimization of therapy with prophylactic antibiotics can prevent recurrent infections and future complications and improve quality of life and longevity of survival. We present a case of a young female with Hyper-IgE Syndrome with a novel mutation in …

Students Excell In Stem With Unh Manchester Summer Program Focused On Esol, Unh Communications And Public Affairs

UNH Today Archive

No abstract provided.

Early-Season Heating Shows Promise Boosting Ginger Harvest, Lori Tyler Gula

UNH Today Archive

No abstract provided.

Applications Of Computational Models On Studying Particulate Systems, Jielin Yu

LSU Doctoral Dissertations

Particulate systems have been widely studied because of its various phenomena and tight relationship with industry applications. In this dissertation, two types of computational models have been adopted to study two problems with different particulate systems: granular self-organization inside a cylinder driven by an orbital-shaker and the optimal design of bypass line for an industrial-scale 8‑leg polyolefin loop reactor.

In the first study, behavior of both single particle and multiple particles in a rotating cylinder has been modeled by discrete element method (DEM) to understand the mechanism of granular self-organization. Sets of studies have then been performed to study the …

Identification Of Susceptibility Pathways For The Role Of Chromosome 15q25.1 In Modifying Lung Cancer Risk., Xuemei Ji, Yohan Bossé, Maria Teresa Landi, Jiang Gui, Xiangjun Xiao, David Qian, Philippe Joubert, Maxime Lamontagne, Yafang Li, Ivan Gorlov, Mariella De Biasi, Younghun Han, Olga Gorlova, Rayjean J Hung, Xifeng Wu, James Mckay, Xuchen Zong, Robert Carreras-Torres, David C Christiani, Neil Caporaso, Mattias Johansson, Geoffrey Liu, Stig E Bojesen, Loic Le Marchand, Demetrios Albanes, Heike Bickeböller, Melinda C Aldrich, William S Bush, Adonina Tardon, Gad Rennert, Chu Chen, M Dawn Teare, John K Field, Lambertus A Kiemeney, Philip Lazarus, Aage Haugen, Stephen Lam, Matthew B Schabath, Angeline S Andrew, Hongbing Shen, Yun-Chul Hong, Jian-Min Yuan, Pier A Bertazzi, Angela C Pesatori, Yuanqing Ye, Nancy Diao, Li Su, Ruyang Zhang, Yonathan Brhane, Natasha Leighl, Jakob S Johansen, Anders Mellemgaard, Walid Saliba, Christopher Haiman, Lynne Wilkens, Ana Fernandez-Somoano, Guillermo Fernandez-Tardon, Erik H F M Van Der Heijden, Jin Hee Kim, Juncheng Dai, Zhibin Hu, Michael P A Davies, Michael W Marcus, Hans Brunnström, Jonas Manjer, Olle Melander, David C Muller, Kim Overvad, Antonia Trichopoulou, Rosario Tumino, Jennifer Doherty, Gary E Goodman, Angela Cox, Fiona Taylor, Penella Woll, Irene Brüske, Judith Manz, Thomas Muley, Angela Risch, Albert Rosenberger, Kjell Grankvist, Mikael Johansson, Frances Shepherd, Ming-Sound Tsao, Susanne M Arnold, Eric B Haura, Ciprian Bolca, Ivana Holcatova, Vladimir Janout, Milica Kontic, Jolanta Lissowska, Anush Mukeria, Simona Ognjanovic, Tadeusz M Orlowski, Ghislaine Scelo, Beata Swiatkowska, David Zaridze, Per Bakke, Vidar Skaug, Shanbeh Zienolddiny, Eric J Duell, Lesley M Butler, Woon-Puay Koh, Yu-Tang Gao, Richard Houlston, John Mclaughlin, Victoria Stevens, David C Nickle, Ma'en Obeidat, Wim Timens, Bin Zhu, Lei Song, María Soler Artigas, Martin D Tobin, Louise V Wain, Fangyi Gu, Jinyoung Byun, Ahsan Kamal, Dakai Zhu, Rachel F Tyndale, Wei-Qi Wei, Stephen Chanock, Paul Brennan, Christopher I Amos

Articles, Abstracts, and Reports

Genome-wide association studies (GWAS) identified the chromosome 15q25.1 locus as a leading susceptibility region for lung cancer. However, the pathogenic pathways, through which susceptibility SNPs within chromosome 15q25.1 affects lung cancer risk, have not been explored. We analyzed three cohorts with GWAS data consisting 42,901 individuals and lung expression quantitative trait loci (eQTL) data on 409 individuals to identify and validate the underlying pathways and to investigate the combined effect of genes from the identified susceptibility pathways. The KEGG neuroactive ligand receptor interaction pathway, two Reactome pathways, and 22 Gene Ontology terms were identified and replicated to be significantly associated …

Identification Of Susceptibility Pathways For The Role Of Chromosome 15q25.1 In Modifying Lung Cancer Risk, Xuemei Ji, Yohan Bossé, Maria Teresa Landi, Jiang Gui, Xiangjun Xiao, David Qian, Philippe Joubert Joubert, Maxime Lamontagne, Yafang Li, Ivan Gorlov, Mariella De Biasi, Younghun Han, Olga Gorlova, Rayjean J. Hung, Xifeng Wu, James Mckay, Xuchen Zong, Robert Carreras-Torres, David C. Christiani, Neil Caporaso, Mattias Johansson, Geoffrey Liu, Stig E. Bojesen, Loic Le Marchand, Demetrios Albanes, Heike Bickeböller, Melinda C. Aldrich, William S. Bush, Adonina Tardon, Gad Rennert, Susanne M. Arnold

Markey Cancer Center Faculty Publications

Genome-wide association studies (GWAS) identified the chromosome 15q25.1 locus as a leading susceptibility region for lung cancer. However, the pathogenic pathways, through which susceptibility SNPs within chromosome 15q25.1 affects lung cancer risk, have not been explored. We analyzed three cohorts with GWAS data consisting 42,901 individuals and lung expression quantitative trait loci (eQTL) data on 409 individuals to identify and validate the underlying pathways and to investigate the combined effect of genes from the identified susceptibility pathways. The KEGG neuroactive ligand receptor interaction pathway, two Reactome pathways, and 22 Gene Ontology terms were identified and replicated to be significantly associated …

Robert James Baker (1942-2018), Obituary, Hugh H. Genoways, Robert D. Bradley, David J. Schmidly, Lisa C. Bradley, James J. Bull, Karen Mcbee, Meredith J. Hamilton, Peter A. Larsen

University of Nebraska State Museum: Mammalogy Papers

First paragraph:

On 30 March 2018, the science of mammalogy and the American Society of Mammalogists lost one of the most influential figures of the last half-century. Robert James Baker died quietly at his home in Lubbock, Texas (Fig. 1). He was born on 8 April 1942 to James Simeon Baker and Laura Cooper in Warren, Arkansas. His father was killed during World War II and his mother remarried, resulting in his growing up with six half-siblings. According to Robert’s autobiography in Going afield (330—number refers to specific publication in “Bibliography”), he spent a good deal of his youth with …

Metabolism Of Primaquine In Normal Human Volunteers: Investigation Of Phase I And Phase Ii Metabolites From Plasma And Urine Using Ultra-High Performance Liquid Chromatography-Quadrupole Time-Of-Flight Mass Spectrometry, Bharathi Avula, Babu L. Tekwani, Narayan D. Chaurasiya, Pius S. Fasinu, N. P. Dhammika Nanayakkara, H. M. T. Bhandara Herath, Yan-Hong Wang, Ji-Yeong Bae, Shabana I. Khan, Mahmoud A. Elsohly, James D. Mcchesney, Peter A. Zimmerman, Ikhlas A. Khan, Larry Walker

Faculty and Student Publications (Open Access)

No abstract provided.

Bioreducible Poly(Amino Ethers) Based Mtor Sirna Delivery For Lung Cancer, Nishant Gandhi, Godeshala Sudhakar, Dana-Lynn T. Koomoa-Lange, Bhavani Miryala, Kaushal Rege, Mahavir B. Chougule

Faculty and Student Publications (Open Access)

No abstract provided.

Pengaruh Pupuk Hayati Dan Pengapuran Terhadap Produktivitas Kedelai Di Tanah Inceptisol Jatinangor, Aep Wawan Irwan, Tati Nurmala

Jurnal Kultivasi

Kedelai merupakan tanaman pangan dengan kandungan protein tinggi sebagai bahan baku utama berbagai makanan, sehingga kebutuhan kedelai di Indonesia selalu tinggi. Hasil kedelai dapat ditingkatkan melalui aplikasi pupuk hayati dan pengapuran. Penelitian ini dilaksanakan di Kebun Percobaan Fakultas Pertanian Universitas Padjadjaran, Jatinangor, Sumedang pada ordo tanah Inseptisol. Penelitian dilakukan dari Maret 2017 sampai Juni 2017. Rancangan percobaannya adalah Rancangan Acak Kelompok, terdiri dari sembilan perlakuan, yaitu tanpa pupuk hayati dan tanpa pengapuran (kontrol); pupuk hayati 5 liter/ha + tanpa pengapuran; pupuk hayati 8 liter/ha + tanpa pengapuran; tanpa pupuk hayati + pengapuran 140 kg/ha; pupuk hayati 5 liter/ha + pengapuran …

Pertumbuhan Dan Hasil Tanaman Cabai (Capsicum Sp.) Yang Diberi Pupuk Hayati Pada Pertanaman Kelapa Sawit (Elaeis Guineensis Jacq.) Tbm I, Cucu Suherman, Mochamad Arief Soleh, Anne Nuraini, Annisa Nurul Fatimah

Jurnal Kultivasi

Penerapan sistem tanam tumpangsari pada tanaman belum menghasilkan (TBM) kelapa sawit merupakan upaya optimalisasi lahan. Pada TBM I terdapat 75 % ruang terbuka yang dapat ditanami tanaman sela, misalnya tanaman cabai. Tanaman sawit umumnya ditanam pada lahan marginal, maka untuk optimasi pertumbuhan tanaman sela perlu dipilih varietas yang baik dan dilakukan pemupukan. Penelitian bertujuan untuk memperoleh pengaruh interaksi terbaik varietas dan dosis pupuk hayati terhadap pertumbuhan dan hasil tanaman cabai yang ditanam pada pertanaman kelapa sawit TBM 1. Percobaan dilakukan mulai Oktober 2017 sampai Pebruari 2018 di Kebun Percobaan Fakultas Pertanian, Universitas padjadjaran. Ordo tanah inceptisol. Tipe curah hujan C …

Pengaruh Dosis Pupuk Hayati Dan Pupuk N, P, K, Terhadap Komponen Hasil Dan Hasil Jagung ( Zea Mays L.) Di Dataran Medium Jatinangor, Agus Wahyudin, Fiky Yulianto Wicaksono, Irfan Maolana

Jurnal Kultivasi

Penelitian ini bertujuan untuk mengetahui pengaruh interaksi dan kombinasi yang terbaik antara pemberian dosis pupuk hayati dan dosis pupuk N, P, K terhadap pertumbuhan dan hasil tanaman jagung hibrida P-12. Percobaan dilakukan di Kebun Percobaan Fakultas Pertanian Universitas Padjadjaran Jatinangor, dengan ketinggian 760 meter di atas permukaan laut, jenis tanah inseptisol dan tipe iklim C3 menurut Oldeman. Rancangan percobaan yang digunakan adalah Rancangan Acak Kelompok (RAK) pola faktorial dengan dua faktor perlakuan. Faktor pertama adalah dosis pupuk N, P, K yang terdiri dari tiga taraf yaitu k1 = 100% pupuk N, P, K, k2 = 75% pupuk N, P, K …

Using Local Fishery Monitoring To Understand Small-Scale Coastal Fisheries In Tanzania, Matthew Robertson

LSU Master's Theses

Nearshore marine fisheries provide the main source of protein for nearly 9 million people in the coastal villages of Tanzania, yet for decades the fisheries have shown signs of overexploitation. These fisheries are small-scale and co-managed by local coastal communities in groups known as Beach Management Units (BMUs). BMUs monitor individual fishing trip data (e.g. gear, vessel, taxa); however, these data have only been analyzed in nationally aggregated statistics and to our knowledge, are not presently used in management decision making. The present thesis aimed to identify the forms of data and information that local fishery monitoring can record about …

Transforming Learning With Information And Communication Technologies: Insights From Three Decades Of Research, Romina Jamieson-Proctor

2009 - 2019 ACER Research Conferences

Since computers first appeared in classrooms, educators have sought to integrate information communication technologies (ICT) into teaching and learning. In Australia, as elsewhere, ICT are widely regarded as critical facilitators of student learning. The ability to use ICT effectively is specified in Australia’s national curriculum as a required general capability. However, despite the educational environment being replete with ICT related programs, our understanding of how students use ICT for learning is still limited. This paper presents insights from the past 30 years of research, which suggest that even though the current ‘climate’ in Australian schools is favourable, teacher confidence and …

The Effect Of Intermittent Normobaric Hyperoxia On Stem Cell Mobilization And Cytokine Expression, Kent Maclaughlin

International Symposium for Hyperbaric Medicine

No abstract provided.

Louisiana Urban And Suburban Homeowners’ Fertilizer Management Behavioral Beliefs, Intentions, And Past Behaviors, Natalie Levy

LSU Doctoral Dissertations

Nutrient runoff of nitrogen and phosphorus from improper lawn and landscape fertilization practices contributes to water quality issues within the Mississippi River drainage basin and the Northern Gulf of Mexico (NRC, 2009a; Robbins & Birkenholtz, 2003). The implementation of fertilizer best management practices has become a critical strategy for reducing nutrient runoff (Carey et al., 2012a; Carey et al., 2013; U.S. EPA, 2005). The purpose of this study was to determine if relationships exist among selected perceptual measures regarding home lawn and landscape fertilizer management practices among Louisiana urban and suburban homeowners. Ajzen’s (1991) Theory of Planned Behavior (TPB) was …

Pubh 7090 – Public Health Practice Trends, Gulzar H. Shah

College of Public Health: Faculty Syllabi (2014-2021)

Today’s public health landscape is increasingly complex and constantly changing. This course focuses on emerging trends and challenges in public health practice that epitomize the increasing complexity and nature of challenges facing public health practitioners.

Pubh 7132 – Scientific Basis Of Public Health, Haresh Rochani

College of Public Health: Faculty Syllabi (2014-2021)

This course explores the scientific basis of 21st century disease processes including a survey of the origins, natural history, factors influencing individual and community risk. Clinical symptoms of diseases impacting humans, both acute and chronic, as well as epidemiologic trends will be also be discussed. Students will obtain an understanding of scientific mechanisms associated with the disease processes with particular focus on using this information in health-related professions and public health decision-making. As such, emphasis will be placed on the understanding and application of proposing community-based solutions designed to break the cycle of disease.

Hbot: An Essential Component For The Regenerative Treatment Of Pain From Sports Injuries, Chronic Inflammation And Infection, John Hughes

International Symposium for Hyperbaric Medicine

This lecture will present the science behind using the synergistic combination of hyperbaric oxygen with stem cell (VSELs) and oxidative IV therapies for chronic pain. I will also present case studies for patients suffering from chronic pain from sports injuries, degenerative, inflammatory, or infections conditions.

Tumor Biology And Hyperbaric Oxygen: Differential Effects In Tumor Versus Normal Tissues, Paul Anderson

International Symposium for Hyperbaric Medicine

When assessing the potential benefits of HBOT in oncology patients occasional confusion arises when extrapolating the cytokine, epigenetic and other effects of HBOT in non-cancerous tissues (neurological and other injuries etc.) versus those in cancerous tissues. This confusion often results in misinterpretation of data and concern over potential harm in HBOT oncology cases. The focus of this presentation is to point out the data supporting these differences as we know it to date and underscore the benefits while decreasing this clinical confusion.

Ischemia Reperfusion Injury: The New Frontier For Wound Healing & Hbot, Jeffrey A. Niezgoda

International Symposium for Hyperbaric Medicine

This session will introduce the attendee to the impact of oxygen free radicals on wound healing. Ischemia reperfusion injury (IRI) and oxygen free radicals are defined and the basic chemistry surrounding reactive oxygen species (ROS) will be discussed. Detailed analysis of the inflammatory phase of wound healing and the role of oxygen free radicals in inflammation are presented.

The Impact Of Mother And Father Stress On Child Externalizing Behaviors, Allison Mccobin

Electronic Theses and Dissertations

The impact of parental stress on child behavioral problems has often been examined through research. A large majority of research indicates a strong correlation between parenting stress and an increase in child behavioral difficulties. However, most studies have focused only on the impact that one parent’s stress has on the child’s behavior, rather than both or comparing the two. Using two separate cross-lagged structural equation models, data from the Fragile Families Child and Wellbeing Study (N = 1010) were analyzed to examine the differences between mother and father parenting stress on child externalizing behavior problems over time (ages three and …

Posttraumatic Growth: The Lived Experience Of Recurrent And Multiple Trauma Survivors Of Kenya’S Skirmishes, 2007 Post-Election Violence, And 2009 National Level Oil Tanker Fire Explosion, Jane C. Lang'at

Electronic Theses and Dissertations

Current research has associated the benefits of posttraumatic growth (PTG) with high levels of stress and trauma that challenge the victim’s assumptive world. The literature reveals that extensive research on PTG has been done on the American, European, and Asian continents but not on the African continent. Yet, how trauma survivors make meaning out of their lived experiences may not be the same globally. This universal phenomenon may also have varied interpretations based on the frequency, intensity, and scope of the traumata, along with the survivors’ socio-economic status (SES) and other benefits and risk factors. In addition, anticipation for high-risk …