Digital Commons Network^™

Draft Genome Sequence Of A Novel Thermofilum Sp. Strain From A New Zealand Hot Spring Enrichment Culture, Anna-Louise Reysenbach, John A. Donaho, Todd M. Hinsch, John F. Kelley, Kathleen Kouba, Mircea Podar, Matthew B. Stott

Biology Faculty Publications and Presentations

A draft genome of a new Thermofilum sp. strain was obtained from an enrichment culture metagenome. Like its relatives, Thermofilum sp. strain NZ13 is adapted to organic-rich thermal environments and has to depend on other organisms and the environment for some key amino acids, purines, and cofactors.

February 2018 Faculty Senate Packet, University Of Nebraska At Kearney Faculty Senate

Faculty Senate Packets

No abstract provided.

Assessment Of Temperature And Ultraviolet Radiation Effects On Sunburn At An Inland U.S. Beach: A Cohort Study, Jason W. Marion, Jiyoung Lee, James Rosenblum, Timothy J. Buckley

EKU Faculty and Staff Scholarship

Background

Increases in outdoor temperature may lead to increases in sunburn, outdoor exposure, and skin cancer in human populations.

Objective

This study aimed to quantify sunburn incidence and risk for Ohio beachgoers exposed to varying outdoor conditions.

Methods

Sunburn incidence data were obtained through a prospective cohort study at East Fork Lake (Cincinnati, Ohio, USA). Recruitment occurred over 26 weekend days. Beach interviews and follow-up telephone interviews obtained exposure and health information. New sunburns were self-reported 8–9 days post-enrollment. Survey data were paired with ultraviolet radiation (UVR) index and temperature data for statistical analysis.

Results

Among 947 beachgoers, new sunburns …

Current Medical Research Winter/Spring 2017, Richard J. Fehring, Kathleen Raviele

College of Nursing Faculty Research and Publications

No abstract provided.

A Method Of Locating The Abutment Screw Access Channel With Cone-Beam Computed Tomography And A 3d-Printed Drilling Guide, Waleed Nasir Asiri, Agnieszka Domagala, Seok-Hwan Cho, Geoffrey A. Thompson

School of Dentistry Faculty Research and Publications

In managing loose abutment screws, locating precisely the position of the screw access channel is difficult. This technique describes the use of cone-beam computed tomography (CBCT) and surgical guide planning software to locate the screw access channel with the intention of retrieving a loosened cement-retained implant-supported prosthesis. The method minimizes damage to the abutment crown assembly.

The Grizzly, February 1, 2018, Valerie Osborne, Naseem Syed, Julie Krasutsky, Kevin Leon, Xichang Wu, Kim Corona, Paige Szmodis, David Mendelsohn, Gabriela Howell

Ursinus College Grizzly Newspaper, 1978 to Present

Spring Semester Opens with "MLK Week" • Ursinus Community Questions Response to Bias Incident • Ursinus Announces Nursing Affiliation with Villanova • Tune in to "Tune Out" • Campus Safety Welcomes a New Family Member • Opinions: Student Calls for Change Regarding Racial Bias Incident; Ansari Allegations Can Help Colleges Communicate About Consent • Swim Team Travels to Florida, Impresses Against Villanova • Eight Straight Wins for Men's Hoops

Core Competencies For Successful Watershed Management Practitioners, Vikram Koundinya, Anne Baird, Jenna Klink, Lois Wolfson, Jane Frankenberger, Joseph Bonnell, Rebecca Power

Journal of Extension

We surveyed participants from three watershed leadership education programs to identify competencies critical to successful watershed management. Participants rated 26 competency areas identified from literature and watershed education curricula for extent of criticality and listed additional competencies needed for successful watershed management. On the basis of those ratings and listings, we propose that competency in the following areas is required: establishing and maintaining partnerships/collaborating, outreach and communication, project and organizational management, landowner interaction/interpersonal skills, facilitative leadership, and, possibly, developing and maintaining a vision for the future. Our findings have implications for designing professional development activities and developing position descriptions for …

4-S Positive Youth Development In Latin America: Professional Schools In Costa Rica, Sandro Lopes, G. John Geldhof, Edmond P. Bowers, Asia Thogmartin

Journal of Extension

As youth development programs established in the United States expand globally, researchers must evaluate their impacts in diverse contexts. The work described in this article established a baseline for assessing the impact of a 4-S youth program at professional technical high schools in Costa Rica. The 4-S program is equivalent to 4-H in English-speaking countries. Results indicate that members of the 4-S program exhibited significantly higher levels of positive youth development than youths in the comparison group (p < .001). We consider how these findings speak to the importance of promoting programs such as 4-S, and we conclude by discussing the implications of this work for practitioners.

Issue 15

The Synapse: Intercollegiate science magazine

No abstract provided.

Inactivation Of Myeloma Cancer Cells By Helium And Argon Plasma Jets: The Effect Comparison And The Key Reactive Species, Zeyu Chen, Qingjie Cui, Chen Chen, Dehui Xu, Dingxin Liu, H. L. Chen, Michael G. Kong

Bioelectrics Publications

In plasma cancer therapy, the inactivation of cancer cells under plasma treatment is closely related to the reactive oxygen and nitrogen species (RONS) induced by plasmas. Quantitative study on the plasma-induced RONS that related to cancer cells apoptosis is critical for advancing the research of plasma cancer therapy. In this paper, the effects of several reactive species on the inactivation of LP-1 myeloma cancer cells are comparatively studied with variable working gas composition, surrounding gas composition, and discharge power. The results show that helium plasma jet has a higher cell inactivation efficiency than argon plasma jet under the same discharge …

Pleiotropic And Novel Phenotypes In The Drosophila Gut Caused By Mutation Of Drop-Dead, Sean Conway, Christine Lynn Sansone, Anika Benske, Kaitlin Kentala, Johan Billen, Jozef Vanden Broeck, Edward M. Blumenthal

Biological Sciences Faculty Research and Publications

Normal gut function is vital for animal survival, and deviations from such function can contribute to malnutrition, inflammation, increased susceptibility to pathogens, diabetes, neurodegenerative diseases, and cancer. In the fruit fly Drosophila melanogaster, mutation of the gene drop-dead (drd) results in defective gut function, as measured by enlargement of the crop and reduced food movement through the gut, and drd mutation also causes the unrelated phenotypes of neurodegeneration, early adult lethality and female sterility. In the current work, adult drd mutant flies are also shown to lack the peritrophic matrix (PM), an extracellular barrier that lines the lumen of the …

Replication Rapidly Recovers And Continues In The Presence Of Hydroxyurea In Escherichia Coli, Samvel A. Nazaretyan, Neda Savic, Michael Sadek, Brandy J. Hackert, Justin Courcelle, Charmain T. Courcelle

Biology Faculty Publications and Presentations

In both prokaryotes and eukaryotes, hydroxyurea is suggested to inhibit DNA replication by inactivating ribonucleotide reductase and depleting deoxyribonucleoside triphosphate pools. In this study, we show that the inhibition of replication in Escherichia coli is transient even at concentrations of 0.1 M hydroxyurea and that replication rapidly recovers and continues in its presence. The recovery of replication does not require the alternative ribonucleotide reductases, NrdEF and NrdDG, or translesion DNA polymerases, Pol II, Pol IV, or Pol V. Ribonucleotides are incorporated at higher frequencies during replication in the presence of hydroxyurea. However, these do not contribute significantly to the observed …

At The Intersection Of Acts And Galatians : New Strategies For Women Church Planters, Carolyn Moore

ATS Dissertations

No abstract provided.

Interspecific Competition Between Egg Parasitoids: Native Fopius Caudatus And Exotic Fopius Arisanus, In Ceratitis Cosyra, Miriam Frida Karlsson, Espérantos O. De Souza, Pascal M. Ayelo, Joseph Ayomidé Zannou, Gbelidji Souvenir Blaise Mègnigbèto, Aimé H. Bokonon-Ganta

All Peer-Reviewed Publications

Tephritidae fruit flies are parasitized by Braconidae wasps, of which some are used in biological control programs. Releases of exotic parasitoids might affect, or be affected by, native species exploiting a common host. We studied interspecific competition between the native African parasitoid Fopius caudatus (Szépligeti) and the exotic Asian parasitoid Fopius arisanus (Sonan) (both Hymenoptera: Braconidae) in African native Ceratitis cosyra Walker (Diptera: Tephritidae). Wasp behaviour on infested fruits and dissection of fruit fly eggs assessed acceptance, oviposition performance and suitability for egg development, parasitism, and effect of parasitism by heterospecific species. While F. arisanus outcompeted F. caudatus in parasitization …

Lanthorn, Vol. 52, No. 39, February 1, 2018, Grand Valley State University

Volume 52, July 10, 2017 - April 23, 2018

Lanthorn is Grand Valley State's student newspaper, published from 1968 to the present.

Association Between Environmental Tobacco Smoke And Dental Caries Amongst 5-14 Years Old Children In Karachi, Pakistan., Anna Ali Nayani, Romaina Iqbal, Syed Iqbal Azam, Farhan Raza Khan, Aysha Habib Khan, Naveed Janjua, Azmina Hussain

Community Health Sciences

Objective:To determine the association between environmental tobacco smoke and dental caries.
Methods:This cross-sectional study was conducted in peri-urban and urban areas of Karachi, from February to August 2014, and comprised children aged 5-14 years. A pre-coded questionnaire for environmental tobacco smoke and food frequency questionnaire for dietary habits were used. Dental examination of children was done to detect caries. Cox-proportional hazard algorithm was used to measure the association of environmental tobacco smoke with dental caries at multivariable level. STATA version 12.0 was used for statistical analysis.
Result:Of the 500 children, 250(50%) each were from peri-urban and urban …

The Evolutionary Mismatch Hypothesis: Implications For Psychological Science, Norman P. Li, Mark Van Vugt, Stephen M. Colarelli

Research Collection School of Social Sciences

Human psychological mechanisms are adaptations that evolved to process environmental inputs, turning them into behavioral outputs that, on average, increase survival or reproductive prospects. Modern contexts, however, differ vastly from the environments that existed as human psychological mechanisms evolved. Many inputs now differ in quantity and intensity or no longer have the same fitness associations, thereby leading many mechanisms to produce maladaptive output. We present the precepts of this evolutionary mismatch process, highlight areas of mismatch, and consider implications for psychological science and policy.

Discovery Orientation, Cognitive Schemas, And Disparities In Science Identity In Early Adolescence, Patricia Wonch Hill, Julia Mcquillan, Amy Spiegel, Judy Diamond

Department of Sociology: Faculty Publications

Why are some youth more likely to think of themselves as a science kind of person than others? In this paper, we use a cognitive social-theoretical framework to assess disparities in science identity among middle school–age youth in the United States. We investigate how discovery orientation is associated with science interest, perceived ability, importance, and reflected appraisal, and how they are related to whether youth see themselves, and perceive that others see them, as a science kind of person. We surveyed 441 students in an ethnically diverse, low-income middle school. Gender and race/ethnicity are associated with science identity but not …

Towards A Digital Earth: Using Archetypes To Enable Knowledge Interoperability Within Geo-Observational Sensor Systems Design, Paul Stacey, Damon Berry

Articles

Earth System Science (ESS) observational data are often inadequately semantically enriched by geo-observational information systems in order to capture the true meaning of the associated data sets. Data models underpinning these information systems are often too rigid in their data representation to allow for the ever-changing and evolving nature of ESS domain concepts. This impoverished approach to observational data representation reduces the ability of multi-disciplinary practitioners to share information in a computable way.

Object oriented techniques typically employed to model data in a complex domain (with evolving domain concepts) can unnecessarily exclude domain specialists from the design process, invariably leading …

Taking Flight – February 2018, Georgia Southern University

College of Business: News & Publications

• Message From the Dean
• Alumni Spotlight -- Moira Sheehan
• AACSB Recognizes Georgia Southern University College of Business Alum as a 2018 Influential Leader
• Defying the Odds: From the Projects of Baltimore to CPA
• Center for Business Analytics and Economics Research Participate in Georgia Economic Outlook
• Start Your Business in Three Days #GS3DS
• TLC Awards & Scholarship Dinner
• Armstrong Graduates Take 1st Place
• Faculty/Staff News

Nanostructured Scaffold For Neural Tissue Regeneration, Walaa Abbas

Theses and Dissertations

Neural regeneration treatment after spinal cord injury (SCI) is still unsatisfactory despite the advances made in the field. One of the main challenges in neural tissue engineering is the axonal growth and directionality. Cell and molecular therapies can enhance the axonal attachment and growth. However, axons may be unsuccessful to maintain their native organization and may grow in a disorganized fashion. Nanofiber scaffolds represent a potential solution for the problem of nerve regeneration and axon extension, as they can mimic the neural tissue extra cellular matrix (ECM) and combine the advantages of the combinatorial therapy for nerve injury in SCI …

Biographies Of Port-Said: Everydayness Of State, Dwellers, And Strangers, Mostafa Mohielden Lotfy

Theses and Dissertations

The thesis examined how the social of the city of Port Said has been assembled, and how the spaces of the city have been produced through the practices of the dwellers and the state. I focused on the processes of the making and the transformation of the people and the city in specific moments. I focused on al tahgeer (the forced migration that followed the outbreak of the 1967 war and lasted until 1974), the declaration of the free trade zone in the mid-1970s, and the massacre of Port Said stadium in 2012. The city of Port Said was built …

Parp Pet Imaging Agents, Brandon Carney

Dissertations, Theses, and Capstone Projects

The poly (adenosine-diphosphate (ADP) ribose) polymerase (PARP) family of enzymes has been of interest to researchers and clinicians for over fifty years, especially the first member of the family, PARP1. This enzyme has become a target for cancer therapeutics due the reliance of highly proliferating cells on PARP1 for genomic maintenance. In the coming age of individualized medicine, however, highly specific therapeutic agents like PARP inhibitors are in need of similarly highly specific companion diagnostic agents. These kind of agents have been made possible with the quickly progressing field of molecular imaging. Specifically, positron emission tomography (PET) has enabled the …

Neonatal Stimulation Of Pkc Epsilon Signaling Normalizes Fragile X-Associated Deficits In Pvn Oxytocin Expression And Later-Life Social And Anxiety Behavior, Alexandra E. Marsillo

Dissertations, Theses, and Capstone Projects

Fragile X Syndrome (FXS) is an inherited developmental disorder characterized by disturbances in emotional and social behavior. Our studies have revealed suppressed hippocampal PKCε expression in Fmr1 knockout (KO) mice, the leading model of FXS. To compensate for this deficiency, we stimulated PKCε in neonatal KO mice by administering a selective PKCε activator, dicyclopropyl-linoleic acid (DCP-LA), and studied its effect on ventral hippocampal neurons and a proximal target of the ventral hippocampus, the hypothalamus, which regulates social and emotional behavior. We observed that at postnatal day 18 (P18), vehicle-treated KO mice displayed increased surface localization of the 3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) …

Militarization Of Conservation, Daniel Ryan Michel

Dissertations, Theses, and Capstone Projects

The world is facing biological diversity extinction of its wildlife solely caused by humans. One of the leading causes of the extinction crisis is attributed to poaching and the illegal trade of wildlife products. In search of finding suitable methods to curb the crisis, a dichotomy of overarching solutions has arisen: those who have advocated for community-based natural resource management and those who support militarized conservation. The focus of this paper is to delineate which method is, if any, the most appropriate when combatting poaching and the illegal wildlife trade. Concentrating on elephants (both African and Asian) and the rhinoceros, …

Impact Of Neurodevelopmental Genes On The Trajectory Of Adhd Severity: A Pilot Study, Agnieszka Mlodnicka

Dissertations, Theses, and Capstone Projects

Attention-deficit/Hyperactivity Disorder (ADHD) is a chronic neurodevelopmental disorder characterized by symptoms of inattention and hyperactivity, and is associated with delays in neural development. To assess the association of genes involved in neurodevelopment with symptoms and trajectory of ADHD, saliva was collected and genotyped from 145 participants from a longitudinal study of preschoolers who were followed annually for 7 years. We examined four single nucleotide polymorphisms (SNPs) in genes associated with neurodevelopment: neuregulin-1 (NRG-1; SNP rs3924999), neurotropin-3 (NT-3; SNP rs6489630), brain-derived neurotrophic factor (BDNF; rs6265), and regulator of G protein signaling 4 (RGS4; rs951439). Hierarchical linear modeling revealed that neuregulin-1 and …

Betty Friedan And Juliet Mitchell: Critiques Of Ideology And Power, Jennie Eagle

Dissertations, Theses, and Capstone Projects

My thesis attends to a common thread of critique in two founding documents of “second-wave” feminism: Betty Friedan’s The Feminine Mystique (1963) and Juliet Mitchell’s “Women: the Longest Revolution.” I am interested in the ways in which both foundational texts de-naturalize male supremacy by defining it as ideological. The concept of ideology as employed by three notable social theorists – Marx’s concept of a social mythology disseminated by ruling elites to uphold various forms of hierarchy, operating through internal contradictions; French communist Louis Althusser’s concept of a social practice disseminated by the institutions of civil society; and Michel Foucault’s identification …

Discovery And Development Of A Three-Component Oxidopyrylium Cycloaddition And Its Application Towards Alpha-Hydroxytropolone Synthesis, Michael P. D'Erasmo

Dissertations, Theses, and Capstone Projects

Historically, natural products have provided unique research opportunities and challenges for organic synthesis, chemical biology, and medicinal chemistry due to their molecular complexity and effects on physiological systems. The total synthesis of natural products has not only produced novel reaction methods and strategies capable of efficiently generating complex structural motifs but also granted access to sufficient quantities of otherwise scarce natural product material for clinical evaluation. These synthetic efforts have facilitated the formation of a transdisciplinary partnership between chemistry, biology, and medicine that has been paramount in elucidating the chemical and pharmaceutical utility of natural products. Chapter I of this …

Neural Hypervigilance In Trauma-Exposed Women, Seungyeon A. Yoon

Dissertations, Theses, and Capstone Projects

Trauma-exposed people often experience hypervigilance, which is a tonic condition of elevated alertness and excessive scanning for potential threat. A cardinal feature of hypervigilance is that no actual threat is needed to evoke or maintain the over-alertness and heightened affective response. However, most neuroimaging research in trauma to date has only focused on reactivity to an actual threat. Thus, the overarching aim of this dissertation was to investigate neural signatures and salivary markers of post-trauma hypervigilance in the absence of threat that can cause impairment in daily functioning and contribute to developing other trauma-related symptoms such as heightened threat reactivity. …

Pipeline To Failure: Social Inequality And The False Promises Of American Public Schooling, Adia Wilson

Dissertations, Theses, and Capstone Projects

My experience as a New York City public school student was absolutely electrifying, though filled with many trials. While my mother would have preferred to put me in private school, having access to some of the world’s greatest institutions and resources offered unique opportunities and exposures. The performing arts provided me with an outlet to express myself and build skills and confidence. In particular, dance education kept me occupied and disciplined in a large city full of danger. Every so often, I witnessed hostile, or even violent exchanges between students, or students and staff. While some of my schoolmates became …