Digital Commons Network^™

Light Regulates The Rubylation Levels Of Individual Cullin Proteins In Arabidopsis Thaliana, Matthew J. Christians, Aron Rottier, Carly Wiersma

Open Access Publishing Support Funded Articles

In plants, the small protein related to ubiquitin (RUB) modifies cullin (CUL) proteins in ubiquitin E3 ligases to allow for efficient transfer of ubiquitin to substrate proteins for degradation by the 26S proteasome. At the molecular level, the conjugation of RUB to individual CUL proteins is transient in nature, which aids in the stability of the cullins and adaptor proteins. Many changes in cellular processes occur within the plant upon exposure to light, including well-documented changes in the stability of individual proteins. However, overall activity of E3 ligases between dark- and light-grown seedlings has not been assessed in plants. In …

The Scholarly Publishing Scene-Getting Attention, Myer Kutz

Against the Grain

No abstract provided.

Juvenile Programming Activities In Detention Facilities: Self-Adjustment And Levels Of Stress, Stephen Davis

Dissertations

The significance of this study was to examine if adolescents in a juvenile detention center in St. Louis City could self-adjust, cope, or adapt to their levels of stress. There was a great deal of literature available supporting the notion of utilizing affective tactics in combating stress levels among various age groups. However, there was very little information provided on at-risk adolescents in a juvenile detention center confronted with dangerous levels of stress. The importance of understanding how these detained adolescents, between the ages of 12 and 17, approached dealing with their stress was not just beneficial to them, but …

And They Were There-Reports Of Meetings, Ramue K. Kubilius, Sever Bordeianu

Against the Grain

No abstract provided.

Oregon Trails-Favorite Books Of 2017, Thomas W. Leonhardt

Against the Grain

No abstract provided.

The Bridge Newsletter Spring 2018, Missouri University Of Science And Technology

The Bridge Newsletter

-Steel Bridge Design Team takes first at ASCE student conference
-Sneed helps lead study abroad course
-ACML gifts
-Schonberg named Fulbright Chair

Latent Toxoplasma Gondii Infection Moderates The Association Between The C677t Mthfr Polymorphism And Cognitive Function In U.S. Adults, Andrew Nathan Berrett

Theses and Dissertations

Sufficient blood concentrations of folate and the products from its metabolism are necessary for several cellular functions. The C677T MTHFR polymorphism, present in over half of the U.S. population, reduces the efficiency of folate metabolism and has been linked to the onset of multiple psychiatric disorders and cognitive decline. The intracellular parasite Toxoplasma gondii can infect the human brain and is associated with increased prevalence of psychiatric disorders and cognitive decline. In vitro studies have found that Toxoplasma gondii may salvage unmetabolized folate from host cells. Since the C677T MTHFR polymorphism and infection by Toxoplasma gondii both affect folate metabolism …

Brexit And Ip: The Great Unraveling?, Graeme B. Dinwoodie, Rochelle Cooper Dreyfuss

Cardozo Law Review

The article examines the impact of Brexit on intellectual property (IP) law in the United Kingdom, arguing that while Brexit may theoretically restore sovereignty, the practical benefits are limited. The U.K. remains deeply intertwined with international IP regimes, and the costs of divergence from European Union (E.U.) law may outweigh the gains. The authors conclude that the U.K. will likely need to recreate many E.U.-derived IP protections to maintain a robust creative sector and global trade efficiency.

The Cowl - V.82 - N.15 - Feb 1, 2018

The Cowl

The Cowl - student newspaper of Providence College. Volume 82, Number 15 - February 1, 2018. 24 pages.

Cyp-450 Epoxygenase Derived Epoxyeicosatrienoic Acid Contribute To Reversal Of Heart Failure In Obesity-Induced Diabetic Cardiomyopathy Via Pgc-1 Alpha Activation, Shailendra Singh, John A. Mcclung, Lars Bellner, Jian Cao, Maayan Waldman, Joseph Schragenheim, Nader G. Abraham

NYMC Faculty Publications

We have previously shown that an Epoxyeicosatrienoic Acid (EET) -agonist has pleiotropic effects and reverses cardiomyopathy by decreasing inflammatory molecules and increasing antioxidant signaling. We hypothesized that administration of an EET agonist would increase Peroxisome proliferator-activated receptor-gamma coactivator (PGC-1alpha), which controls mitochondrial function and induction of HO-1 and negatively regulates the expression of the proinflammatory adipokines CCN3/NOV in cardiac and pericardial tissues. This pathway would be expected to further improve left ventricular (LV) systolic function as well as increase insulin receptor phosphorylation. Measurement of the effect of an EET agonist on oxygen consumption, fractional shortening, blood glucose levels, thermogenic and …

Concussion, Microvascular Injury, And Early Tauopathy In Young Athletes After Impact Head Injury And An Impact Concussion Mouse Model, Chad A. Tagge, Andrew M. Fisher, Olga V. Minaeva, Amanda Gaudreau-Balderrama, Juliet A. Moncaster, Xiao-Lei Zhang, Omid Miry, Linnea R. Vose, Katisha R. Gopaul, Chirag Upreti, Patric K. Stanton, Ann C. Mckee, Lee E. Goldstein

NYMC Faculty Publications

The mechanisms underpinning concussion, traumatic brain injury, and chronic traumatic encephalopathy, and the relationships between these disorders, are poorly understood. We examined post-mortem brains from teenage athletes in the acute-subacute period after mild closed-head impact injury and found astrocytosis, myelinated axonopathy, microvascular injury, perivascular neuroinflammation, and phosphorylated tau protein pathology. To investigate causal mechanisms, we developed a mouse model of lateral closed-head impact injury that uses momentum transfer to induce traumatic head acceleration. Unanaesthetized mice subjected to unilateral impact exhibited abrupt onset, transient course, and rapid resolution of a concussion-like syndrome characterized by altered arousal, contralateral hemiparesis, truncal ataxia, locomotor …

Condition-Dependence Of Blue Plumage Coverage In Indigo Buntings Passerina Cyanea, Spencer B. Hudson, Travis E. Wilcoxen

Biology Faculty Publications

Nuptial plumage colouration is seemingly favoured by females of avian species with regards to sexual selection. This particular secondary sexual characteristic has been previously shown to be a condition-dependent signal of individual quality among passerines with pigment-based colouration (i.e. yellows and reds). In contrast, relationships between structural plumage colouration (i.e. blues) and aspects of both physical quality and physiological function have been understudied. Using free-living Indigo Buntings (Passerina cyanea) as a study species, we compared the percentage of blue feather coverage to body condition, innate immune responses, antioxidant capacity, stress physiology, reproductive physiology, and …

February 2018 News Releases, University Of Montana--Missoula. Office Of University Relations

University of Montana News Releases, 1928, 1956-present

No abstract provided.

Vol 63 #1, Melanie Argo

MPLA Newsletter

No abstract provided.

Eight-Legged Encounters—Arachnids, Volunteers, And Art Help To Bridge The Gap Between Informal And Formal Science Learning, Eileen Hebets, Melissa Welch-Lazoritz, Pawl Tisdale, Patricia Wonch Hill

Eileen Hebets Publications

Increased integration and synergy between formal and informal learning environments is proposed to provide multiple benefits to science learners. In an effort to better bridge these two learning contexts, we developed an educational model that employs the charismatic nature of arachnids to engage the public of all ages in science learning; learning that aligns with the Next Generation Science Standards (NGSS Disciplinary Core Ideas associated with Biodiversity and Evolution). We created, implemented, and evaluated a family-focused, interactive science event—Eight-Legged Encounters (ELE)—which encompasses more than twenty modular activities. Volunteers facilitated participant involvement at each activity station and original …

Resistance In 27 Rice Cultivars To Sugarcane Borer (Lepidoptera: Crambidae), F. Correa, C. L. T. Silva, A. P. Pelosi, A. C. S. Almeida, E. A. Heinrichs, J. A. F. Barrigossi, F. G. Jesus

Department of Entomology: Faculty Publications

Rice (Oryza sativa L.) is considered one of the most important crops in the world, and the sugarcane borer, Diatraea saccharalis Fabricius (Lepidoptera: Crambidae), is among the key pests damaging the crop in the Americas. The objective of this work was to identify rice genotypes as a source of resistance to D. saccharalis. Rice plants were infested in the greenhouse and subsequently evaluated for damage, larval weight and survival, and stem size. The cultivars “Bonança,” “Caripuna,” “IR 42,” “Canela de Ferro,” “SWA Norte,” “BR IRGA 409,” “Pepita,” “Serra Dourada,” “Araguaia,” “Xingú,” “Tangará,” and “Soberana” showed antibiosis, antixenosis, or …

Policy Determinants Of Physical Activity Across The Life Course: A Dedipac' Umbrella Systematic Literature Review, Anna Puggina, Katina Aleksovska, Christoph Buck, Con Burns, Greet Cardon, Angela Carlin, Simon Chantal, Donatella Ciarapica, Giancarlo Condello, Tara Coppinger, Cristina Cortis, Sara D'Haese, Marieke De Craemer, Andrea Di Blasio, Sylvia Hansen, Licia Iacoviello, Johann Issartel, Pascal Izzicupo, Lina Jaeschke, Martina Kanning, Aileen Kennedy, Fiona Chun Man Ling, Agnes Luzak, Giorgio Napolitano, Julie Anne Nazare, Camille Perchoux, Tobias Pischon, Angela Polito, Alessandra Sannella, Holger Schulz, Rhoda Sohun, Astrid Steinbrecher

Publications

Background Despite the large number of studies and reviews available, the evidence regarding the policy determinants of physical activity (PA) is inconclusive. This umbrella systematic literature review (SLR) summarizes the current evidence on the policy determinants of PA across the life course, by pooling the results of the available SLRs and meta-analyses (MAs). Methods A systematic online search was conducted on MEDLINE, ISI Web of Science, Scopus and SPORTDiscus databases up to April 2016. SLRs and MAs of observational studies investigating the association between policy determinants of PA and having PA as outcome were considered eligible. The extracted data were …

A Real-Time Wireless Sweat Rate Measurement System For Physical Activity Monitoring, Andrew Brueck, Tashfin Iftekhar, Alicja B. Stannard, Kumar Yelamarthi, Tolga Kaya

Exercise Science Faculty Publications

There has been significant research on the physiology of sweat in the past decade, with one of the main interests being the development of a real-time hydration monitor that utilizes sweat. The contents of sweat have been known for decades; sweat provides significant information on the physiological condition of the human body. However, it is important to know the sweat rate as well, as sweat rate alters the concentration of the sweat constituents, and ultimately affects the accuracy of hydration detection. Towards this goal, a calorimetric based flow-rate detection system was built and tested to determine sweat rate in real …

On-Chip Optical Sensors, Mohamed Elsayed

Theses and Dissertations

Adding more functionality to chips is an important trend in the advancement of technology. During the past couple of decades, integrated circuit developments have focused on keeping Moore's Law alive "More of Moore". Moore's law predicts the doubling of the number of transistors on an integrated circuit every year. My research objectives revolve around "More than Moore", where different functionalities are sought to be integrated on chip. Sensing in particular is becoming of paramount importance in a variety of applications. Booming healthcare costs can be reduced with early diagnosis, which requires improved sensitivity and lower cost. To halt global warming, …

Tuning The Nature Of Defect States In Black Tio2 Nanostructures, Moamen Mohamed Soliman

Theses and Dissertations

Black TiO2 is being widely investigated due to its superior optical activity. Herein, the limitations of the hydrogenation process are unraveled by exploiting the fundamental tradeoffs affecting the overall efficiency of the water splitting process. Different reduction rates are applied to sub-100 nm TiO2 highly efficient short nanotubes. X-ray photoelectron spectroscopy reveals changes in the stoichiometry of TiO2 with the reduction rate. UV-Vis and Raman spectra reveal that high reduction rates promote the formation of the rutile phase in TiO2, which is inactive towards water splitting. The electrochemical analysis discloses that low reduction rates induce higher concentration of localized electronic …

Frequency Of Macroprolactin In Hyperprolactinemia, Aysha Habib Khan, Noreen Abbas Sherazi, Mirza Zain Baig

Department of Pathology and Laboratory Medicine

Objective: To determine the frequency of Macroprolactin (MaPRL) in patients with increased total prolactin and its clinical and financial impact.
Study Design: Cross-sectional study.
Place and Duration of Study: Section of Clinical Chemistry, Department of Pathology and Laboratory Medicine, The Aga Khan University Hospital, Karachi, from March to May 2015. Methodology: Patients with high total prolactin were screened by polyethylene glycol (PEG) precipitation for determination of MaPRL. Clinical history, imaging work-ups, and cost incurred in further investigations were collected by telephonic interview after verbal consent. Patients were stratified into true hyperprolactinemia and macroprolactinemia after PEG treatment, based on monomeric prolactin …

A-Mode And B-Mode Ultrasound Measurement Of Fat Thickness: A Cadaver Validation Study, Dale R. Wagner, Brennan J. Thompson, D. Andy Anderson, Sarah Schwartz

Kinesiology and Health Science Faculty Publications

Background/Objectives With technological advances, there has been a resurgence in ultrasound as a method to measure subcutaneous fat thickness. Despite the increased interest in this methodology, research comparing A-mode and B-mode ultrasound devices is lacking. Subcutaneous fat thickness measured by a low resolution (2.5 MHz) A-mode ultrasound and a high resolution (12 MHz) B-mode ultrasound were compared to the actual fat thickness in dissected cadavers.

Subjects/Methods Subcutaneous fat thickness of six cadavers was measured at the abdomen, thigh, triceps, and calf (plus chest for males and suprailiac for females) with both ultrasound devices before the cadavers were dissected and site-specific …

Inhibition Of Human Monoamine Oxidase A And B By Flavonoids Isolated From Two Algerian Medicinal Plants., Farida Larit, Khaled M. Elokely, Narayan D. Chaurasiya, Samira Benyahia, Manal A. Nael, Francisco León, Mohammad Sanad Abu-Darwish, Thomas Efferth, Yan-Hong Wang, Djamila Belouahem-Abed, Samir Benayache, Babu L. Tekwani, Stephen J. Cutler

Faculty and Student Publications (Open Access)

Monoamine oxidases (MAOs) are outer mitochondrial membrane flavoenzymes. They catalyze the oxidative deamination of a variety of neurotransmitters. MAO-A and MAO-B may be considered as targets for inhibitors to treat neurodegenerative diseases and depression and for managing symptoms associated with Parkinson's and Alzheimer's diseases.

One-Step, Stereoselective Synthesis Of Octahydrochromanes Via The Prins Reaction And Their Cannabinoid Activities, Shuneize Slater, Pradeep B. Lasonkar, Saqlain Haider, Moneerah J. Alqahtani, Amar G. Chittiboyina, Ikhlas A. Khan

Faculty and Student Publications (Open Access)

No abstract provided.

Functional Activation During A Cognitive Control Task In Healthy Youth Specific To Externalizing Or Internalizing Behaviors., Katherine Karlsgodt, Angelica A. Bato, Toshikazu Ikuta, Bart D. Peters, Pamela Derosse, Philip R. Szeszko, Anil K. Malhotra

Faculty and Student Publications (Open Access)

Externalizing behaviors are negative behaviors expressed outwardly, including rule breaking, aggression, and risk taking; internalizing behaviors are expressed inwardly, including depression, withdrawal, and anxiety. Such behavior can cause problems in early life and predict difficulties across the lifespan. There is evidence for a relationship between executive function and both externalizing and internalizing. However, although these behaviors occur along a spectrum, there is little neuroimaging research on this relationship in typically developing youth.

The Healthy, Hunger-Free Kids Act: The Fight Must Go On, Jenny Nelson, Jessica Nelson

Denver Law Review Forum

No abstract provided.

Contested Visions: The Value Of Systems Theory For Corporate Law, Tamara Belinfanti, Lynn A. Stout

Cornell Law Faculty Publications

Despite the dominant role corporations play in our economy, culture, and politics, the nature and purpose of corporations remains hotly contested. This conflict was brought to the fore in the recent Supreme Court opinions in Citizens United and Hobby Lobby. Although the prevailing narrative for the past quarter-century has been that corporations “belong” to shareholders and should pursue “shareholder value,” support for this approach, which has been justified as essential for managerial accountability, is eroding. It persists today primarily in the form of the argument that corporations should seek “long-term” shareholder value. Yet, as this Article shows, when shareholder value …

Monthly Paleostreamflow Reconstruction From Annual Tree-Ring Chronologies, James H. Stagge, David E. Rosenberg, R. J. Derose, Tammy M. Rittenour

Publications

Paleoclimate reconstructions are increasingly used to characterize annual climate variability prior to the instrumental record, to improve estimates of climate extremes, and to provide a baseline for climate-change projections. To date, paleoclimate records have seen limited engineering use to estimate hydrologic risks because water systems models and managers usually require streamflow input at the monthly scale. This study explores the hypothesis that monthly streamflows can be adequately modeled by statistically decomposing annual flow reconstructions. To test this hypothesis, a multiple linear regression model for monthly streamflow reconstruction is presented that expands the set of predictors to include annual streamflow reconstructions, …

Expanding Spheres: Atoms To Earth, Local To Global, Science To Society, Sarah Green

Distinguished Lecture Series

Best case scenario. Worst case scenario. Sarah Green talks about the human impacts of climate change and responding to those changes on local and global scales. Green, a professor in both the Department of Chemistry and the Great Lakes Research Center at Michigan Technological University, presented the Spring 2018 Distinguished Lecture at the Michigan Tech Research Forum. Her lecture, Expanding Spheres: Atoms to Earth, Local to Global, Science to Society, was Thursday, February 15, 2018.

Robotic Motion Learning Framework To Promote Social Engagement, Rachel Burns, Myounghoon Jeon, Chung Hyuk Park

Department of Psychology and Human Factors Publications

Abstract Imitation is a powerful component of communication between people, and it poses an important implication in improving the quality of interaction in the field of human–robot interaction (HRI). This paper discusses a novel framework designed to improve human–robot interaction through robotic imitation of a participant’s gestures. In our experiment, a humanoid robotic agent socializes with and plays games with a participant. For the experimental group, the robot additionally imitates one of the participant’s novel gestures during a play session. We hypothesize that the robot’s use of imitation will increase the participant’s openness towards engaging with the robot. Experimental results …