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2018

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Cortical Trajectory Pedicle Screws For The Fixation Of Traumatic Thoracolumbar Fractures., Jacob C Wochna, Rudy Marciano, Irina Catanescu, Joel Katz, M Chance Spalding, Kailash Narayan Jun 2018

Cortical Trajectory Pedicle Screws For The Fixation Of Traumatic Thoracolumbar Fractures., Jacob C Wochna, Rudy Marciano, Irina Catanescu, Joel Katz, M Chance Spalding, Kailash Narayan

Trauma and Acute Care Articles

Objective Cortical bone trajectory pedicle screws (CBT) have a different trajectory compared to traditional pedicle screws (PS) and they may confer biomechanical advantages in some patient populations. We hypothesize that the placement of CBT in traumatic thoracolumbar fractures could be an alternative technique to the traditional utilization of PS. Methods Single surgeon, retrospective study was performed at a Level 1 Trauma Center from 2013 to 2017. All patients aged between 18 and 90 years with operative AO classification A, B, and C traumatic thoracolumbar fractures were included. Patients with pathological fractures, active spinal infections, or history of vertebral augmentation were …


Chemical Investigation Of Bioactive Marine Extracts, Selam Hagos Jun 2018

Chemical Investigation Of Bioactive Marine Extracts, Selam Hagos

USF Tampa Graduate Theses and Dissertations

Natural products have been a fundamental source of medicinal scaffolds for decades; with sixty percent of marketed drugs. Many synthetic chemists are focused on synthesizing potent and nontoxic compounds for pharmaceutical targets, however, nature is still proving to be a source of new bioactive compounds. Produced by the host organism for defense, reproduction and communication, secondary metabolites also demonstrate promising bioactivity against human pathogens. Hence, natural product chemists continue their quest for new leads.

As a continuation of these efforts, this thesis attempts to explore fungi and sponges for new chemistry, and ultimately, new drug candidates. Antarctica is largely untapped; …


Managing Forest Disease Spread With Tangible Participatory Models, Devon Gaydos, Anna Petrasova, Vaclav Petras, Richard Cobb, Ross Meentemeyer Jun 2018

Managing Forest Disease Spread With Tangible Participatory Models, Devon Gaydos, Anna Petrasova, Vaclav Petras, Richard Cobb, Ross Meentemeyer

International Congress on Environmental Modelling and Software

Forest diseases fundamentally diminish the health and functioning of our valuable forest resources. Landscape-scale management efforts to reduce disease spread are a priority but can be fraught with questions about how best to allocate limited resources. Management efforts can be greatly enhanced by spatiotemporal models of disease spread which allow the comparison of alternative scenarios. In many cases, however, models are developed without user-friendly interfaces or consideration of stakeholder motivations, fueling a knowledge-practice gap where better science has not necessarily lead to better management. Tangible Landscape, an open-source participatory modeling tool, has been designed to address this challenge. Stakeholders can …


Formulation Of An Approach For Integrating Earth Observations, Climate Forecasting And Land-Surface Modelling In Order To Predict Outbreaks Of Dengue Fever And Zika Virus In Vietnam, Quillon Harpham, Darren Lumbroso, Gina Tsarouchi Jun 2018

Formulation Of An Approach For Integrating Earth Observations, Climate Forecasting And Land-Surface Modelling In Order To Predict Outbreaks Of Dengue Fever And Zika Virus In Vietnam, Quillon Harpham, Darren Lumbroso, Gina Tsarouchi

International Congress on Environmental Modelling and Software

Dengue fever occurs in 141 countries with 122,000 cases reported in Vietnam in 2016. The epidemiological situation there has been worsened by the failure of health systems to maintain adequate control of the species of mosquito that spread dengue. Several studies have emphasised the significant links between weather variability and infectious diseases, highlighting the potential for developing early warning systems for epidemics. The same methods could also be used to forecast outbreaks of zika, which has recently begun to be reported in Vietnam.

This presentation describes the results of a study, supported by the UK Space Agency, resulting in a …


Computational Insights Into The Structures, Mechanisms, And Chemical Properties Of Metal Complexes, Enzymes, And Bio-Molecules, Thomas J. Paul Jun 2018

Computational Insights Into The Structures, Mechanisms, And Chemical Properties Of Metal Complexes, Enzymes, And Bio-Molecules, Thomas J. Paul

Open Access Dissertations

In this thesis, we have focus on the following three projects: (1) the inhibition of amyloid beta aggregation, (2) structural and mechanical properties of amyloid peptides, and (3) complex biological systems of molecular recognition pertaining to hydrolysis. In the first project, we have looked at the inhibition of early and late forms of Aß peptides using heparin derived disaccharides, small molecules, and a Rhenium centered photoluminescence probe. We have determined and characterized the most relevant binding sites of these complexes to both the monomeric and fibrillar forms of the Aß peptide. Currently, the aggregation of biomolecules has been implicated in …


Volume 55, Number 45: June 27, 2018, University Of North Dakota Jun 2018

Volume 55, Number 45: June 27, 2018, University Of North Dakota

University Letter Archive

No abstract provided.


Purifying Selection In The Toll-Like Receptors Of Song Sparrows Melospiza Melodia, Martha J. Nelson-Flower, Ryan R. Germain, Elizabeth A. Macdougall-Shackleton, Sabrina S. Taylor, Peter Arcese Jun 2018

Purifying Selection In The Toll-Like Receptors Of Song Sparrows Melospiza Melodia, Martha J. Nelson-Flower, Ryan R. Germain, Elizabeth A. Macdougall-Shackleton, Sabrina S. Taylor, Peter Arcese

Faculty Publications

Variation in immune gene sequences is known to influence resistance to infectious diseases and parasites, and hence survival and mate choice, across animal taxa. Toll-like receptors (TLRs) comprise one essential gene family in the vertebrate innate immune system and recognize evolutionarily conserved structures from all major microorganism classes. However, the causes and consequences of TLR variation in passerine birds remain largely unexplored. We examined 7 TLR genes in song sparrows (Melospiza melodia), a species that is studied across North America. We then examined sequences from 4 unduplicated TLRs (TLR1LB, TLR3, TLR4, and TLR15) from birds in 2 parts of the …


Enlisting Student Nurses In A Lebanese National Campaign To Immunize Children Against Polio, Christine W. Abbyad Jun 2018

Enlisting Student Nurses In A Lebanese National Campaign To Immunize Children Against Polio, Christine W. Abbyad

International Nursing Research Congress (INRC)

There is great value in having nursing students engage in public health projects. One such endeavor was a polio immunization campaign in Lebanon. Reports of polio in neighboring Syria necessitated immunization of Lebanese children under the age of five. Junior and senior nursing students who participated learned many valuable lessons.


Density And Pond Habitat Affect Survival And Growth Rates In Larval Columbia Spotted Frogs (Rana Luteiventris), Sidney A. Patchett, Allystair D. Jones, Mark C. Belk Jun 2018

Density And Pond Habitat Affect Survival And Growth Rates In Larval Columbia Spotted Frogs (Rana Luteiventris), Sidney A. Patchett, Allystair D. Jones, Mark C. Belk

Western North American Naturalist

Juvenile survival and growth are critical determinants of evolutionary fitness in most organisms. However, specific effects of population density and habitat quality on survival and growth of larvae vary widely among amphibian species. The Columbia spotted frog (Rana luteiventris), like many amphibians in the arid western United States, is a species of conservation concern, especially in the southern part of its range. To determine how density and habitat affect vital rates of Columbia spotted frog during the larval period, we performed a controlled experiment. Larval growth and survival in the Columbia spotted frog are determined by density of …


Aurora Freedom 55/65 News, 1996 Summer, Advocate Aurora Health Jun 2018

Aurora Freedom 55/65 News, 1996 Summer, Advocate Aurora Health

Aurora Health Care Books, Documents, and Pamphlets

Aurora Health Care, Milwaukee, WI: Summer 1996 edition of Freedom 55/65 News for members in the metro Milwaukee area. Article topics include evaluation of health services, community health services, community events, esophageal problems, hearing loss workshops, health and wellness events, diabetes, and sharps disposal.


Landscape Structure And Ecology Influence The Spread Of A Bat Fungal Disease, Thomas M. Lilley, Jani Anttila, Lasse Ruokolainen Jun 2018

Landscape Structure And Ecology Influence The Spread Of A Bat Fungal Disease, Thomas M. Lilley, Jani Anttila, Lasse Ruokolainen

KIP Articles

1. White‐nose syndrome (WNS), affecting multiple North American bat species during the hibernation period, is a highly pathogenic disease caused by the psychrophilic fungus Pseudogymnoascus destructans (Pd). Because the fungal pathogen persists in the hibernation site environment independently of the hosts, previous theory on spatial disease dynamics cannot predict WNS epidemics. However, the ability to understand factors contributing to the spread of white‐nose syndrome (WNS) in North America is crucial to the management of infected and susceptible bat populations as well as the conservation of threatened and endangered bat species. 2. Utilizing recent theory on environmental opportunistic pathogens, we modelled …


The Role Of Clinical Sign And The Added Value Of Procalcitonin In Determining The Existance Of Infection In The Treated Diabetic Foot Ulcer, Andra Aswar, Em Yunir, Anis Karuniawati, Kuntjoro Harimurti Jun 2018

The Role Of Clinical Sign And The Added Value Of Procalcitonin In Determining The Existance Of Infection In The Treated Diabetic Foot Ulcer, Andra Aswar, Em Yunir, Anis Karuniawati, Kuntjoro Harimurti

Jurnal Penyakit Dalam Indonesia

No abstract provided.


Ethical Issues In Designing Interventions For Behavioural Change, Gyuchan Thomas Jun, Fernando Carvalho, Neil Sinclair Jun 2018

Ethical Issues In Designing Interventions For Behavioural Change, Gyuchan Thomas Jun, Fernando Carvalho, Neil Sinclair

DRS Biennial Conference Series

This paper reflects on fundamental ethical issues concerning designing for behavioural change, in order to raise questions about the factors that should be considered by design practitioners when developing interventions. It draws on existing literature on philosophical ethics, moral psychology and design. It proposes a list of ethical questions and considerations to be made throughout the design process. A case study addressing behavioural changes in antibiotics prescriptions (for Urinary Tract Infections) was carried out to demonstrate how the ethical questions identified are asked and considered. We provide a framework for addressing these issues with the hope that it will help …


Synthesis Of Small Molecules That Target Metalloenzymes, Akram M. Hazeen Jun 2018

Synthesis Of Small Molecules That Target Metalloenzymes, Akram M. Hazeen

Doctoral Dissertations

Metalloenzymes have gained interest in drug development. In this study, small molecules with metal binding groups were synthesized to target two metalloenzymes: alkaline nuclease (UL12) that causes a viral infection resulted in the simplex herpes 1 disease. The other enzyme was E. colienolase which is essential for the survival of several pathogens. Three general motifs were modified in this study inspired from natural products. Tropolone was diversified through aminocarbonylation and cross coupling reaction with diethyl phosphite to provide a series of tropolone derivatives. Pyridone series which has two sites for diversifications was also prepared. The last series was based …


Series Solution Of Typhoid Fever Model Using Differential Transform Method, O. J. Peter, O. B. Akinduko, C. Y. Ishola, O. A. Afolabi, A. B. Ganiyu Jun 2018

Series Solution Of Typhoid Fever Model Using Differential Transform Method, O. J. Peter, O. B. Akinduko, C. Y. Ishola, O. A. Afolabi, A. B. Ganiyu

Malaysian Journal of Computing (MJoC)

This paper presents an analysis of PSIuIeTR type model, which are used to study the transmission dynamics of typhoid fever diseases in a population. Basic idea of typhoid fever disease transmission using compartmental modeling is discussed. Differential Transformation Method (DTM) is discussed in detail, which is used to compute the series solution of the non-linear system of differential equation governing the model equations. The validity of the (DTM) in solving the proposed model is established by classical fourth-order Runge-Kutta method which is implemented in Maple 18. Graphical results confirm that (DTM) is in good agreement with RK-4 and this produced …


Pre-Exposure Prophylaxis (Prep) In Primary Care Settings: Current Problems And Proposed Solutions, Yeow Chye Ng, Angela Caires, Jack J. Mayeux Jun 2018

Pre-Exposure Prophylaxis (Prep) In Primary Care Settings: Current Problems And Proposed Solutions, Yeow Chye Ng, Angela Caires, Jack J. Mayeux

International Nursing Research Congress (INRC)

Pre-exposure prophylaxis (PrEP) is a lifesaving HIV prevention medication that should not be solely introduced by primary care providers in a primary care setting. Urgent Care centers, hospitals, and community free clinics may also play a vital role in providing this important medical service.


Introducing Pre-Exposure Prophylaxis (Prep) Therapy For Populations Experiencing Homelessness, Angela Caires, Yeow Chye Ng, Jack J. Mayeux Jun 2018

Introducing Pre-Exposure Prophylaxis (Prep) Therapy For Populations Experiencing Homelessness, Angela Caires, Yeow Chye Ng, Jack J. Mayeux

International Nursing Research Congress (INRC)

Individuals who are experiencing homelessness are at increased risk for exposure to HIV because of precarious living situations and crowded shelter populations. The utilization of pre-exposure prophylaxis (PrEP) by agencies providing healthcare for the homeless is urgently needed.


The Need For Pre-Exposure Prophylaxis (Prep) In The Urgent Care Setting, Jack J. Mayeux, Yeow Chye Ng, Angela Caires Jun 2018

The Need For Pre-Exposure Prophylaxis (Prep) In The Urgent Care Setting, Jack J. Mayeux, Yeow Chye Ng, Angela Caires

International Nursing Research Congress (INRC)

The role of urgent care clinics in facilitating PrEP service for prevention in HIV is under-explored. There is a lack of guidelines for initiating PrEP in the UC setting which delivers care to an increasing number of individuals. A PrEP initiation protocol is crucial for use in the UC setting.


Borrelia Burgdorferi Invasion Of B Lymphocytes, Jacob Bailey, Richard Robinson Jun 2018

Borrelia Burgdorferi Invasion Of B Lymphocytes, Jacob Bailey, Richard Robinson

Journal of Undergraduate Research

The goal of this project was to determine if Borrelia Burgdorferi’s linear plasmid 36 is required for intracellular localization in B lymphocytes. A more complete understanding of the intracellular localization of B. burgdorferi may provide the means to effective Lyme treatment. It has been proposed that intracellular localization of Lyme spirochetes may be, at least in part, responsible for Post Treatment Lyme Disease. As the spirochetes are safe within human cells, Borrelia are able to evade host immune system responses and be protected from antibiotic treatment. A more complete understanding of the intracellular localization of B. burgdorferi may provide the …


Calibration Of The National Ecological Observatory Network's Airborne Observation Platforms, Nathan Leisso, Joe Boardman, Tristan Goulden, Ian Crocker Jun 2018

Calibration Of The National Ecological Observatory Network's Airborne Observation Platforms, Nathan Leisso, Joe Boardman, Tristan Goulden, Ian Crocker

The Characterization and Radiometric Calibration for Remote Sensing Annual Meeting (CALCON)

The National Ecological Observatory Network (NEON) is a continental-scale ecological observation facility funded by the National Science Foundation (NSF). NEON's mission is to enable understanding and forecasting of the impacts of land-use change and invasive species by providing the infrastructure and consistent methodologies for the collection of continental-scale ecological data. The Airborne Observation Platform (AOP) will play a unique role by collecting regional scale remote sensing data surrounding the NEON sites. This is expected to enable scaling of individual in-situ measurements collected by NEON or others to those collected by external satellite-based remote sensing systems.

The airborne payload consists of …


Full Issue 47(2) Jun 2018

Full Issue 47(2)

International Journal of Speleology

No abstract provided.


High-Titer Rapid Response Platform For Epidemic Preparedness, José Castillo Jun 2018

High-Titer Rapid Response Platform For Epidemic Preparedness, José Castillo

Vaccine Technology VII

Recent epidemics & pandemics have exposed serious flaws in global response to infectious disease outbreaks, as no vaccine were available to stop the diseases, due to limited market incentive.

New initiatives, such as the CEPI “Coalition for Epidemic Preparedness Innovations” are focusing on accelerating vaccine development for priority disease and ensuring their global availability.

In this light, Univercells is dedicated to designing novel biomanufacturing technologies to accommodate new products at short notice.

Univercells innovative manufacturing concept is designed to enable the rapid generation of potent vaccine candidates against a broad spectrum of targets, with the capacity to rapidly scale-up and …


Improving Alcohol Use Screening And Brief Intervention: A Multidisciplinary Mobile App Randomized Control Trial, Alexa Colgove Curtis Jun 2018

Improving Alcohol Use Screening And Brief Intervention: A Multidisciplinary Mobile App Randomized Control Trial, Alexa Colgove Curtis

International Nursing Research Congress (INRC)

This presentation will review the global epidemiology of alcohol misuse and clinical strategies to combat the health consequences of hazardous alcohol misuse including multidisciplinary SBIRT training, and the development, implementation and randomized control trial evaluation of a Screening, Brief Intervention and Referral to Treatment (SBIRT) mobile app.


Ripple Effects Of The Belo Monte Dam: A Syndemic Approach To Addressing Health Impacts For The Downstream Community Of Gurupá, Cynthia A. Pace Jun 2018

Ripple Effects Of The Belo Monte Dam: A Syndemic Approach To Addressing Health Impacts For The Downstream Community Of Gurupá, Cynthia A. Pace

USF Tampa Graduate Theses and Dissertations

This dissertation examines the public health impacts of a large dam project on a downstream community using the framework of Syndemic Theory. The particular focus is the Belo Monte Dam, located in the Brazilian Amazon, and its impact on the community of Gurupá, Pará. At the present time the Belo Monte Dam, which is nearing completion, stands out in scale as being the world’s third largest dam complex. Gurupá is a community well known (and well-studied) in the social science literature as Amazon Town. The aims of this study are to assess the pre-existing public health of Gurupá, as well …


Week Of June 19, 2018, New York Medical College Jun 2018

Turan To Lead The Sparkman Center For Global Health, Staff Jun 2018

Turan To Lead The Sparkman Center For Global Health, Staff

Browse All News

No abstract provided.


Indwelling Catheter Challenge, Monina Hernandez Jun 2018

Indwelling Catheter Challenge, Monina Hernandez

International Nursing Research Congress (INRC)

A study done in a New Zealand hospital identified nurses' (n=14) baseline knowledge of evidence-based indwelling catheter management using a 25-item pre- and post-test. Sixty-four percent received scores below 70%. An education intervention significantly improved (p < .05) nurses' post-test scores. This interactive session challenges nurses to take the test.


Health And The Hospital Workplace Environment Of Us Nurses, Susan M. Priano, Carol Dawson-Rose, Oisaeng Hong Jun 2018

Health And The Hospital Workplace Environment Of Us Nurses, Susan M. Priano, Carol Dawson-Rose, Oisaeng Hong

International Nursing Research Congress (INRC)

A cross-sectional study using the American Nurses Association HealthyNurseTM online health risk appraisal data to describe hospital registered nurses' health, perceived health and their perception of the health and safety of the hospital work environment.


Health And Housing: Altruistic Medicalization Of America’S Affordability Crisis, Dayna Bowen Matthew Jun 2018

Health And Housing: Altruistic Medicalization Of America’S Affordability Crisis, Dayna Bowen Matthew

Law and Contemporary Problems

No abstract provided.


Slaying Little Dragons: The Impact Of The Guinea Worm Eradication Program On Dracunculiasis Disability Averted From 1990 To 2016, Elizabeth A. Cromwell, Sharon Roy, Dieudonne P. Sankara, Adam Weiss, Jeffrey Stanaway, Ellen Goldberg, David M. Pigott, Heidi Larson, Stein Emil Vollset, Zulfiqar Ahmed Bhutta Jun 2018

Slaying Little Dragons: The Impact Of The Guinea Worm Eradication Program On Dracunculiasis Disability Averted From 1990 To 2016, Elizabeth A. Cromwell, Sharon Roy, Dieudonne P. Sankara, Adam Weiss, Jeffrey Stanaway, Ellen Goldberg, David M. Pigott, Heidi Larson, Stein Emil Vollset, Zulfiqar Ahmed Bhutta

Department of Paediatrics and Child Health

Background: The objective of this study was to document the worldwide decline of dracunculiasis (Guinea worm disease, GWD) burden, expressed as disability-adjusted life years (DALYs), from 1990 to 2016, as estimated in the Global Burden of Disease study 2016 (GBD 2016). While the annual number of cases of GWD have been consistently reported by WHO since the 1990s, the burden of disability due to GWD has not previously been quantified in GBD.
Methods: The incidence of GWD was modeled for each endemic country using annual national case reports. A literature search was conducted to characterize the presentation of GWD, translate …