Digital Commons Network^™

A Review Of Epstein Barr Virus Immunity, Pathogenesis And Immunotherapies, Heather Stuart

Senior Honors Projects

Epstein – Barr Virus (EBV), a member of the Herpesviridae family, is commonly known as the cause of infectious mononucleosis. While EBV infection has acute effects, its primary significance in human health stems from its association with multiple cancers resulting from chronic infection. EBV first establishes infection in epithelial cells of the oropharynx, where it is lytic, and later establishes latent infection in B cells, where it exists in latency for remainder of the host’s lifetime. Dendritic cells and natural killer cells are first to control expansion of the infection followed by cytotoxic T cells and helper T cells. Through …

Performance Evaluation Of Mission Critical Communications Services Over Lte Networks, Kehinde Olumide Olasupo

Theses and Dissertations

he existing Private/Professional Mobile Radio (PMR) technologies designed specifically for Mission Critical Communication (MCC) systems are narrowband and wideband devices, with limited network data capacity in emergency scenarios. They are majorly used to support MCC voice communications and low data rate applications during mission critical operations. However, the need for broadband systems that would support high radio data capacity keep increasing during major incidents and accident scenarios. Because of this, the MCC agencies were attracted by the broadband capabilities of Long Term Evolution (LTE) technology. But, the uplink capacity of LTE- based MCC systems is still a concern. In planning …

Front Matter

Hofstra Law Review

No abstract provided.

Deciding Not To Decide: Federal Courts' Discretion To Decline Review And Miller V. City Of Wickliffe, Tommy Tobin

Hofstra Law Review

No abstract provided.

Homeless, Hungry, And Targeted: A Look At The Validity Of Food-Sharing Restrictions In The United States, Samantha Holloway

Hofstra Law Review

No abstract provided.

The English Legacy Of The Second Amendment - History And Myth, Allen R. Kamp

Hofstra Law Review

According to the majority opinion of Justice Scalia in District of Columbia v. Heller, pre-Second Amendment adoption English history informs the Amendment’s meaning. The majority opinion discusses the historical background after analyzing the language of the Amendment: “Putting all of these textual elements together, we find that they guarantee the individual right to possess and carry weapons in case of confrontation. This meaning is strongly confirmed by the historical background of the Second Amendment. We look to this because it has always been widely understood that the Second Amendment, like the First and Fourth Amendments, codified a pre-existing right.”

My …

Midbrain Circuit Regulation Of Individual Alcohol Drinking Behaviors In Mice, Barbara Juarez, Carole Morel, Stacy M. Ku, Yutong Liu, Hongxing Zhang, Sarah Montgomery, Hilledna Gregoire, Efrain Ribeiro, Marshall Crumiller, Ciorana Roman-Ortiz, Jessica J. Walsh, Kelcy Jackson, Denise E. Croote, Yingbo Zhu, Song Zhang, Leandro F. Vendruscolo, Scott Edward, Amanda Roberts, Georgia E. Hodes, Yongke Lu, Erin S. Calipari, Dipesh Chaudhury, Allyson K. Friedman, Ming Hu Han

ETSU Faculty Works

Alcohol-use disorder (AUD) is the most prevalent substance-use disorder worldwide. There is substantial individual variability in alcohol drinking behaviors in the population, the neural circuit mechanisms of which remain elusive. Utilizing in vivo electrophysiological techniques, we find that low alcohol drinking (LAD) mice have dramatically higher ventral tegmental area (VTA) dopamine neuron firing and burst activity. Unexpectedly, VTA dopamine neuron activity in high alcohol drinking (HAD) mice does not differ from alcohol naive mice. Optogenetically enhancing VTA dopamine neuron burst activity in HAD mice decreases alcohol drinking behaviors. Circuit-specific recordings reveal that spontaneous activity of nucleus accumbens-projecting VTA (VTA-NAc) neurons …

Ensuring Student Success In Full-Day Kindergarten: Purposeful Professional Development And Professional Learning Communities, Amy Houlihan

Dissertations

The change leadership model, developed by Wagner et al. (2008), was utilized to assess the context, culture, conditions and competencies of a large suburban school district during the early stages of districtwide implementation of full-day kindergarten. With overwhelming support from families, teachers and administrators, the change plan revolves around ongoing and purposeful professional development for staff building upon systematic work of Professional Learning Communities in order to provide a high quality full-day kindergarten program across twenty-three kindergarten program sites. When districts and schools focus on purposeful professional development and enhanced practice of Professional Learning Communities programs can work to provide …

Transforming The American Education System: A Program Evaluation Of A School District’S 1:1 Chromebook Pilot, Michael Marassa

Dissertations

The focus of this program evaluation is to determine the impact of a Google Chromebook 1:1 program on the learning process and educational experience for students and teachers. The participants attend two high schools of a high-performing public-school district in an affluent Chicago suburb. The following research questions guide the program evaluation:

• What is the measurable relationship between academic performance and engagement and the 1:1 Chromebook program?
• What changes in instructional practice occur with the implementation of 1:1 Chromebooks?

A literature review presents current research in areas that explore 21st Century Skills, Tony Wagner’s Global Achievement Gap, constructivist instructional pedagogy, …

Hmgcs2 Is A Key Ketogenic Enzyme Potentially Involved In Type 1 Diabetes With High Cardiovascular Risk., Sanket Kumar Shukla, Weijing Liu, Kunal Sikder, Sankar Addya, Amrita Sarkar, Yidong Wei, Khadija Rafiq

Center for Translational Medicine Faculty Papers

Diabetes increases the risk of Cardio-vascular disease (CVD). CVD is more prevalent in type 2 diabetes (T2D) than type 1 diabetes (T1D), but the mortality risk is higher in T1D than in T2D. The pathophysiology of CVD in T1D is poorly defined. To learn more about biological pathways that are potentially involved in T1D with cardiac dysfunction, we sought to identify differentially expressed genes in the T1D heart. Our study used T1D mice with severe hyperglycemia along with significant deficits in echocardiographic measurements. Microarray analysis of heart tissue RNA revealed that the T1D mice differentially expressed 10 genes compared to …

Antibacterial Activity Of Zno Nanoparticles On Silica Thin Film For Wastewater Treatment, S Chanrawangyot, S Rattanachan, A Watcharenwong, T Fangsuwannarak

Journal of Metals, Materials and Minerals

Zinc Oxide nanoparticles on silica matrix thin films were prepared by the Sol-gel method and dip coating on ceramic tiles. In this study, EC (Ethyl cellulose) and TP (alpha-terpineol) used as a binder and a solvent in Sol-gel method, respectively, were studied on the characteristics of thin films. The thin films were dried and calcined at the temperature of 500, 600˚C soaking 30 minutes with the heating rate of 1˚C/minutes. The result of Glancing X-Ray Diffraction showed that thin films were ZnO phase on the amorphous phase of silica matrix. Scanning electron microscope showed the ZnO nanoparticles dispersed on thin …

Properties Of Natural Rubber Latex Filled With Bacterial Cellulose Produced From Pineapple Peels, T Saowapark, E Chaichana, A Jaturapiree

Journal of Metals, Materials and Minerals

Bacterial cellulose (BC) is natural biopolymers with unique properties such as high purity and high tensile strength. These properties considerably support for use as filler in rubber applications. In this research, BC was produced from fermentation by Acetobacter xylinum. Additionally, pineapple peels (agricultural waste) were evaluated for carbon sources in BC's production process. Natural rubber latex (NRL) compound was then incorporated BC with various loadings of 0, 5, 10 and 15 phr (parts per hundred of rubber) for enhancement properties of NRL. Furthermore, NRL filled with BC (NRL-BC) compounds were prevulcanized at 70°C for 2 hours and then NRL-BC sheets …

Physical And Optical Properties Of 20cao-(80-X)B2o3-Xzno Glass System, N Jearnkulprasert, O Chaemlek, N Wantana, J Kaewkhao

Journal of Metals, Materials and Minerals

The 20CaO-(80-x)B2O3-xZnO glasses were prepared by melt quenching technique (where x=0, 5, 15 and 20 mol%) in order to study in the physical and optical properties. These glass compositions were heated to 1200 ºC for 3 hours and annealed at 500ºC for 3 hours. Clear glass samples were obtained from these compositions. The density, molar volume, refractive index, optical spectra (in the wavelength of 190-1100 nm), optical band gap, optical basicity and polarizability of glass samples have been investigated in this work.

The Mirage Of Use Restrictions, Ric Simmons

North Carolina Law Review

This Article concludes that most types of use restrictions do not have sufficient legal justifications. It first reviews the many possible applications of use restrictions and discusses five potential doctrinal bases to justify them: (1) apply an “ongoing seizure” doctrine; (2) create a purpose test for the exclusionary rule; (3) re-define a “search” as including the processing of information, not just its collection; (4) make the purpose of the data collection a factor in determining whether collecting the data is a search; and (5) limit which government agencies are allowed access to the data that is collected. This Article then …

Development Of Pre-Stressed Retrofit Strategies For Mitigating Fatigue Cracking In Steel Waterway Lock Gate Components, Christine Michelle Lozano

Graduate Theses and Dissertations

Lock gates are an important part of the transportation infrastructure within the United States (US), having many economic, safety, and environmental benefits over rail and highway transportation systems. Unfortunately, many existing lock gates throughout the US have reached or exceeded their initial design life and require frequent repairs to remain in service. Unscheduled repairs often increase as gates age, having a local economic impact on freight transport which can create economic ripples throughout the nation. Fatigue and corrosion are key causes of unscheduled service interruptions, degrading lock gate components over time. Additionally, because lock gates are submerged during operation, crack …

Progress On The Hupo Draft Human Proteome: 2017 Metrics Of The Human Proteome Project., Gilbert S Omenn, Lydie Lane, Emma K Lundberg, Christopher M Overall, Eric W Deutsch

Articles, Abstracts, and Reports

The Human Proteome Organization (HUPO) Human Proteome Project (HPP) continues to make progress on its two overall goals: (1) completing the protein parts list, with an annual update of the HUPO draft human proteome, and (2) making proteomics an integrated complement to genomics and transcriptomics throughout biomedical and life sciences research. neXtProt version 2017-01-23 has 17 008 confident protein identifications (Protein Existence [PE] level 1) that are compliant with the HPP Guidelines v2.1 ( https://hupo.org/Guidelines ), up from 13 664 in 2012-12 and 16 518 in 2016-04. Remaining to be found by mass spectrometry and other methods are 2579 "missing …

Cognitive Trajectory Changes Over 20 Years Before Dementia Diagnosis: A Large Cohort Study., Ge Li, Eric B Larson, Jane B Shofer, Paul K Crane, Laura E Gibbons, Wayne Mccormick, J D Bowen, Mary Lou Thompson

Articles, Abstracts, and Reports

BACKGROUND/OBJECTIVES: Longitudinal studies have shown an increase in cognitive decline many years before clinical diagnosis of dementia. We sought to estimate changes, relative to "normal" aging, in the trajectory of scores on a global cognitive function test-the Cognitive Abilities Screening Instrument (CASI).

DESIGN: A prospective cohort study.

SETTING: Community-dwelling members of a U.S. health maintenance organization.

PARTICIPANTS: Individuals aged 65 and older who had no dementia diagnosis at baseline and had at least two visits with valid CASI test score (N = 4,315).

MEASUREMENTS: Average longitudinal trajectories, including changes in trajectory before clinical diagnosis in those who would be diagnosed …

Welfare And Federalism's Peril, Andrew Hammond

Washington Law Review

Recent scholarship on American federalism lacks case studies to inform that scholarship’s trans-substantive insights and claims. This Article examines the last two decades of devolution brought about by the 1996 Welfare Reform Act (PRWORA). It details the history of PRWORA and how the funding mechanism built into Temporary Assistance for Needy Families (TANF)—the TANF block grant—guaranteed the program’s deterioration. The Article documents the program’s failure to respond to increased need among poor families after Hurricane Katrina and in the Great Recession, showing how the federal government’s use of TANF in both crises teach us the limits of fiscally devolved programs. …

The Declining Presbyterian Church, Joshua A. Edwards

Religious Studies

In this thesis I will discuss how the Presbyterian Church has been declining in membership and in the number of people attending weekly services. Within this study, I use my own church, Niagara Presbyterian Church in Niagara Falls, NY as a case study to further prove what is happening within the Presbyterian Church. Though the trend of declining church attendance can be seen across most denominations, I will show how the Presbyterian Church specifically is struggling and show why it is unique in its situation along with other characteristics of the decline that have happened across the denominations. I close …

Popularity Prediction, Andrew Furgiuele

Computer Science

With the rise in popularity of the Internet, data describing unique types of items has been collected into easy to access sources. Using this newly acquired data, is it possible to predict if an item will become a bestseller while another fade away with time? Popularity prediction is a problem that has attracted a great deal of research recently, and for good reason. The ability to predict an items future rise to popularity or fall to obscurity is a possibly priceless skill and sought out in many different industries such as sales, investments, and marketing. This report enumerates and analyzes …

El Leñador, December 2017, El Leñador Staff

El Leñador Newspaper

El Leñador is an English and Spanish newspaper produced by Humboldt State University students. Our staff cover and provide news to Latinx and other diverse communities on campus and in Humboldt County. We are committed to providing relevant news and expanding the representations and stories told about people of color and other marginalized groups. Our work helps create more social, political and cultural diversity in local media.

El Leñador es un periodico en español y inglés producido por estudiantes de la Universidad Estatal de Humboldt. Nuestro personal cubre y provee noticias a la comunidad Latinx y otras comunidades diversas en …

Influence Of Social And Economic Factors On Elementary Student Health In Northwest Arkansas, Megan Marks

The Eleanor Mann School of Nursing Undergraduate Honors Theses

A child’s wellbeing is influenced by many factors related to the environment they are raised in. The purpose of this study was to investigate the relationship between a child’s social and economic factors and his or her health. A convenience sample of 588 2nd and 4th grade children was taken from three elementary schools in Springdale Independent School District. Health status was represented by calculations of each child’s body mass index (BMI) and number of days counted absent from school. Socioeconomic and demographic factors examined include the child’s grade level, gender, ethnicity, number of parents over the household, number of …

Modifiable Factors Impeding Nurses’ Willingness To Report In A Disaster, Kate Hutchison

The Eleanor Mann School of Nursing Undergraduate Honors Theses

This research project investigates what modifiable factors impede nurses’ willingness to report to work during a disaster. The survey sample were nurses in the United States. Survey methodology was a snowball sampling initiated among nurses attending a PhD Program at the University of Texas at Tyler as well as the utilization of Facebook to recruit participants. The survey instrument determined likelihood of nurses reporting to work in various types of disasters and factors that may impede them from responding to such disasters. The online survey asked thirty-five “select all that apply” type questions and the results will be used to …

The New Sister-State Sovereign Immunity, Michael H. Hoffheimer

Washington Law Review

The Article reviews the constitutional status of sister-state sovereign immunity. It argues that the parity requirement announced in Franchise Tax Board v. Hyatt (2016) is a temporary compromise that is supported by neither the purposes of the Full Faith and Credit Clause nor by cases cited by the Court. It further argues that parity is bad policy because parity overprotects states for acts they commit beyond their borders and under protects the interests of forum states in regulating conduct within their territorial jurisdiction. But the Article breaks from most scholarship. It suggests that the Court went too far in Nevada …

Safeguarding Washington's Trade Secrets: Protecting Businesses From Public Records Requests, John Delaney

Washington Law Review

Lawmakers constantly balance competing interests. They decide where to draw lines so that societal goals are accomplished without ignoring the needs of those who will be affected by their choices. The Washington State Legislature is now in the process of addressing the line between government transparency and the protection of private companies’ trade secrets. Companies who provide technology to the federal government are susceptible to losing their trade secrets through a public records request. The Washington State Legislature is currently reviewing the trade secret exception to the Public Records Act to ensure it is continuing to protect companies from losing …

The Helicopter State: Misuse Of Parens Patriae Unconstitutionally Precludes Individual And Class Claims, Gabrielle J. Hanna

Washington Law Review

The doctrine of parens patriae allows state attorneys general to represent state citizens in aggregate litigation suits that are, in many ways, similar to class actions and mass-tort actions. Its origins, however, reflect a more modest scope. Parens patriae began as a doctrine allowing the British king to protect those without the ability to protect themselves, including wards and mentally disabled individuals. The rapid expansion of parens patriae standing in the United States may be partly to blame for the relative absence of limiting requirements or even well-developed case law governing parens patriae suits. On the one hand, class actions …

Reinvigorating Urban Under Space:Towards A New Type Of Public Landscape, Yujia Wang, Gandong Cai

NAKHARA (Journal of Environmental Design and Planning)

The proposition of this paper is to examine the agency of landscape in subverting, energizing and reinvigorating a specific kind of deserted space in cities - Urban Under Space. The term Urban UnderSpace refers to residual infrastructural spaces, such as under-bridge space, abandoned subway stations, air raid shelters, etc. The wide availability and continued generation of Urban Under Space in cities that were investigated in North America and Asia reflect a problem in modern planning. But it also provides an opportunity of positioning these piecesas a network of new urban landscapes that can offer a unique and attractive public space …

A Design Methodology For Continuous Fiber Additive Manufacturing Using Advanced Computer Aided Engineering Techniques, Nicholas Venter

Mechanical and Aerospace Engineering Theses - Archive

A design methodology for Continuous Carbon Fiber Additive Manufacturing (CCFAM) developed using Computer Aided Engineering (CAE) techniques takes advantage of both the mechanical strength of composite materials and the Fused Filament Fabrication (FFF) method. By performing topology optimization and Finite Element Analysis (FEA) on a load-bearing part, engineers can design much lighter optimized parts that are just as strong as those produced using FFF. This weight reduction is achieved by relying on the mechanical strength of continuous carbon fibers printed alongside a traditional thermoplastic matrix. The FFF additive manufacturing method enables the production of complex shapes, which can match the …

Effect Of Underfill Material & Gap Height On Reliability Of Low-K Large-Die Flip Chip Package Under Thermal Loading, Paul Crisanth

Mechanical and Aerospace Engineering Theses - Archive

The reliability assessment of package assembly is important to predict the performance of any microelectronic devices. Formation of fatigue cracks at the interface between the solder joint and component is the common failure occurring in widely used microelectronic devices. Lead-free solders and advanced silicon process nodes with the low-k dielectrics flip chip package are used and are facing significant reliability challenges. The mismatch of coefficient of thermal expansion (CTE) between the chip and substrate affect solder joint reliability. The underfill encapsulant packaging is widely used to improve chip device reliability. In this paper, we are studying the effect of different …

Editorial Team

The Prairie Light Review

No abstract provided.