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Sexual Education Pedagogy In The Global South: Pubmed Data In The Age Of Globalization, Grace A. Walker-Stevenson

University Honors Theses

This systematic review and subsequent analysis examines the harm caused by inadequate sexual education in countries with minimal access to healthcare. This review relies on PubMed as its singular database. PubMed is a free search engine that utilizes the MEDLINE database of references on life sciences and biomedical topics. This database is maintained by The United States Library of Medicine and The National Institutes of Health, therefore it is an authoritative entity on the subject of health research. Assessing the breadth of knowledge represented in PubMed related to this issue can be extrapolated to estimate the current state of salient …

Chlamydia Screening In Women At A University Student Health Center, Jaime K. Carroll, Karen Macauley

Doctor of Nursing Practice Final Manuscripts

The purpose of this evidenced-based project was to increase chlamydia pre- screening and screening in women under age 25 presenting with urinary symptoms. Interventions included chlamydia pre-screening alerts embedded into the electronic medical record. Three-month evaluation showed a chlamydia pre-screening rate of 100% and an increase in chlamydia screening by 9%.

Methodological Approach To The Ex Vivo Expansion And Detection Of T. Cruzi-Specific T Cells From Chronic Chagas Disease Patients, Gonzalo R. Acevedo, Silvia A. Longhi, Alcinette Bunying, Nazila Sabri, Augusto Atienza, Maria P. Zago, Radleigh Santos, Valeria A. Judkowski, Clemencia Pinilla, Karina A. Gomez

Mathematics Faculty Articles

The discovery of T cell epitopes is essential not only for gaining knowledge about host response to infectious disease but also for the development of immune-intervention strategies. In Chagas disease, given the size and complexity of the Trypanosoma cruzi proteome and its interaction with the host’s immune system, the fine specificity of T cells has not been extensively studied yet, and this is particularly true for the CD4+ T cell compartment. The aim of the present work was to optimize a protocol for the generation of parasite-specific memory T cell lines, representative of their in vivo precursor populations and capable …

Final Report: Status Of The Arizona Toad (Anaxyrus Microscaphus) In New Mexico, Mason J. Ryan, Jacek Tomasz Giermakowski, Ian M. Latella, Howard L. Snell

Biology Faculty & Staff Publications

This report covers the fourth consecutive year (2013-2016) of research on the population dynamics, ecology, and conservation status of the Arizona Toad (Anaxyrus microscaphus) in New Mexico. The year 2016 represented the rare opportunity to study the effects of El Niño, which typically brings above average precipitation to New Mexico, on the breeding behavior and ecology of the Arizona toad. We expected that the El Niño-driven above average precipitation during the winter of 2015 and spring of 2016 would result in increased detection of toads at breeding sites, especially those sites that were dry in 2013, 2014, and …

Synchronized And Mixed Outbreaks Of Coupled Recurrent Epidemics, Muhua Zheng, Ming Zhao, Byungjoon Min, Zonghua Liu

Publications and Research

Epidemic spreading has been studied for a long time and most of them are focused on the growing aspect of a single epidemic outbreak. Recently, we extended the study to the case of recurrent epidemics (Sci. Rep. 5, 16010 (2015)) but limited only to a single network. We here report from the real data of coupled regions or cities that the recurrent epidemics in two coupled networks are closely related to each other and can show either synchronized outbreak pattern where outbreaks occur simultaneously in both networks or mixed outbreak pattern where outbreaks occur in one network but do not …

Food Allergies Abroad: An Exploration Of The Experiences Individuals With Food Allergies Face While Studying Abroad, Danielle M. Roberge

Capstone Collection

Food allergies are a life-threatening medical condition that can result in a potentially fatal allergic reaction known as anaphylaxis. Food allergies affect roughly 15 million United States citizens and this number is growing, currently there is no cure. Young adults are most at risk to experience this life-threatening reaction. As more students with food allergies are entering colleges and universities to pursue a higher education, they are also becoming increasingly interested in studying abroad; however, there are few resources available. This research paper aims to explore the various challenges those with food allergies experience while studying abroad. To understand these …

Predicting Cryptic Links In Host-Parasite Networks, Tad Dallas, Andrew W. Park, John M. Drake

Faculty Publications

Networks are a way to represent interactions among one (e.g., social networks) or more (e.g., plant-pollinator networks) classes of nodes. The ability to predict likely, but unobserved, interactions has generated a great deal of interest, and is sometimes referred to as the link prediction problem. However, most studies of link prediction have focused on social networks, and have assumed a completely censused network. In biological networks, it is unlikely that all interactions are censused, and ignoring incomplete detection of interactions may lead to biased or incorrect conclusions. Previous attempts to predict network interactions have relied on known properties of network …

Comparison Of Biomarker Based Matrix Assisted Laser Desorption Ionization-Time Of Flight Mass Spectrometry (Maldi-Tof Ms) And Conventional Methods In The Identification Of Clinically Relevant Bacteria And Yeast, Ali Kassim, Valentin Pflüger, Zul Premji, Claudia Daubenberger, Gunturu Revathi

Pathology, East Africa

Background: MALDI-TOF MS is an analytical method that has recently become integral in the identification of microorganisms in clinical laboratories. It relies on databases that majorly employ pattern recognition or fingerprinting. Biomarker based databases have also been developed and there is optimism that these may be superior to pattern recognition based databases. This study compared the performance of ribosomal biomarker based MALDI-TOF MS and conventional methods in the identification of selected bacteria and yeast.

Methods: The study was a cross sectional study identifying clinically relevant bacteria and yeast isolated from varied clinical specimens submitted to a clinical laboratory. The identification …

Offering Self-Administered Oral Hiv Testing As A Choice To Truck Drivers In Kenya: Predictors Of Uptake And Need For Guidance While Self-Testing, Elizabeth A. Kelvin, Gavin George, Eva Mwai, Eston N. Nyaga, Joanne E. Mantell, Matthew L. Romo, Jacob O. Odhiambo, Kaymarlin Govender

Publications and Research

We assessed predictors of choosing self-administered oral HIV testing in the clinic with supervision versus the standard provider-administered blood test when offered the choice among 149 Kenyan truck drivers, described the types of guidance participants needed during self-testing and predictors of needing guidance. Overall, 56.38% of participants chose the self-test, 23.49% the provider-administered test, and 20.13% refused testing. In the adjusted regression models, each additional unit on the fatalism and self-efficacy scales was associated with 0.97 (p = 0.003) and 0.83 (p = 0.008) times lower odds of choosing the self-test, respectively. Overall, 52.38% of self-testers did so correctly without …

Influenza Vaccination As A Condition Of Employment At An Integrated Health System: A Six Year Review, John Brill, Mar Hermanoff, Mary Jo Capodice, Angela Tonozzi, Jennifer L. Farrar, Zarina Dawoodbhai, Gwen Baumel

Aurora UW Family Medicine Faculty – Milwaukee

No abstract provided.

Evaluating The Hiv Continuum Of Care Within A Large Integrated Health System, Michael J. Williams, Thomas J. Dilworth

Pharmacy and Pharmacology

No abstract provided.

Evaluation Of Socioeconomic Factors And Achievement Of Sustained Virologic Response (Svr) In The Treatment Of Hepatitis C Virus (Hcv), Erika Aldag, Rachel Pedersen, Andrew Ackerman, Vikraman Gunabushanam, Ajay Sahajpal, Siddesh Besur

Pharmacy and Pharmacology

Poster presented at: Aurora Scientific Day; May 24, 2017; Milwaukee, WI.

The Community-Acquired Pneumonia Organization (Capo) Cloud-Based Research Platform (The Capo-Cloud): Facilitating Data Sharing In Clinical Research, William A. Mattingly, Timothy L. Wiemken, Stephen P. Furmanek, Paula Peyrani, Robert R. Kelley, Julio A. Ramirez

The University of Louisville Journal of Respiratory Infections

Background: Pneumonia is a costly and deadly respiratory disease that afflicts millions every year. Advances in pneumonia care require significant research investment and collaboration among pneumonia investigators. Despite the importance of data sharing for clinical research it remains difficult to share datasets with old and new investigators. We present CAPOCloud, a web-based pneumonia research platform intended to facilitate data sharing and make data more accessible to new investigators.

Methods: We establish the first two use cases for CAPOCloud to be the automatic subsetting and constraining of the CAPO database and the automatic summarization of the database in aggregate. We use …

A New Journal Section: Patient Management, Forest W. Arnold, Rodrigo Cavallazzi

The University of Louisville Journal of Respiratory Infections

No abstract provided.

Sepsis In Patients With Ventilator Associated Pneumonia Due To Methicillin- Resistant Staphylococcus Aureus: Incidence And Impact On Clinical Outcomes, Anupama Raghuram, Martin Gnoni, Timothy Lee Wiemken, Leslie Beavin, Julio A. Ramirez, Forest W. Arnold, Marcus J. Zervos, Daniel H. Kett, Thomas M. File Jr., Gary Stein, Kimbal D. Ford, Paula Peyrani, The Impact-Hap Investigators

The University of Louisville Journal of Respiratory Infections

Background: Sepsis is a clinical syndrome associated with organ dysfunction due to a dysregulated host response to infection. Methicillin-resistant Staphylococcus aureus (MRSA) Ventilator-associated pneumonia (VAP) is a serious infection frequently associated with sepsis. The objectives of this study were to define the incidence of sepsis and clinical failure in patients with MRSA VAP.

Methods: This was a secondary analysis of the Improving Medicine through Pathway Assessment of Critical Therapy in Hospital-Acquired Pneumonia (IMPACT-HAP) study database. VAP was defined according to CDC criteria. MRSA VAP was considered when MRSA was isolated from a tracheal aspirate or bronchoalveolar lavage. We …

Impact Of Obesity On Mortality In Hospitalized Patients With Pneumonia Due To 2009 H1n1 Influenza A Virus Versus Other Etiologies, Martin A. Espinosa-Ginic, Ryan T. Hurt, Stephen P. Furmanek, Paula Peyrani, Julio A. Ramirez, Timothy Lee Wiemken, The Capo Investigators

The University of Louisville Journal of Respiratory Infections

Background: Reports from the 2009 H1N1 influenza A virus (2009 H1N1) pandemic indicate increased mortality in obese patients hospitalized with pneumonia. However, articles published prior to the pandemic have suggested that obesity may be a protective factor for mortality in these patients. The objective of this study was to compare the impact of obesity on mortality in hospitalized patients with pneumonia due to the 2009 H1N1 versus pneumonia due to other etiologies.

Methods: This was a secondary analysis of the CAPO international cohort study. Study groups were defined as follows: Group One, pneumonia due to 2009 H1N1: Patients hospitalized with …

Short Duration Of Antibiotic Therapy In Hospitalized Patients With Community-Acquired Pneumonia: Results From The Capo International Cohort Study, Alejandro Chirino Navarta, Paula Peyrani, Timothy L. Wiemken, Marcos I. Restrepo, James D. Chalmers, Carlos M. Luna, Francesco Blasi, Julio A. Ramirez, Stefano Aliberti

The University of Louisville Journal of Respiratory Infections

Introduction: Experts suggest a short duration of antibiotic therapy (DOT) in responding patients with community-acquired pneumonia (CAP). The aim of this study was to evaluate clinical outcomes after hospital discharge among patients treated with short-course antibiotic therapy (SCT) vs. long-course antibiotic therapy (LCT) for CAP.

Methods: A secondary analysis of the Community-Acquired Pneumonia Organization (CAPO) database from January 2007 to June 2013 was performed, including hospitalized CAP patients who reached clinical stability within 5 days. Two groups were identified: patients who were treated with antibiotic therapy for a total duration of 5 days or less (SCT Group) vs. …

The Presence Of Copd Does Not Influence Clinical Outcomes In Hospitalized Patients With Community-Acquired Pneumonia, Rosemeri Maurici, Alessandra Morello Gearhart, Vanessa Viríssimo Maciel, Forest Arnold, Francisco Fernandez, Annuradha K. Persaud, Stephen Furmanek, Timothy Wiemken, Julio Ramirez, Rodrigo Cavallazzi

The University of Louisville Journal of Respiratory Infections

Introduction

Community-acquired pneumonia (CAP) is a leading cause of death worldwide. Chronic obstructive pulmonary disease (COPD) is a well-established risk factor for development of CAP. What is not as clear is the impact of COPD in the outcomes of patients with CAP. In this study, we compared the outcomes of CAP in COPD and non-COPD patients.

Methods

This was a retrospective cohort study. We conducted a secondary analysis of the Community-Acquired Pneumonia Organization (CAPO) international cohort study database, which includes patients with CAP admitted to several hospitals throughout the world. Outcomes were time to clinical stability, length of hospital stay, …

Analysis Of The Local And Systemic Cytokine Response Profiles In Patients With Community-Acquired Pneumonia. Relationship With Disease Severity And Outcomes., Rafael Fernandez-Botran, Timothy Lee Wiemken, Robert R. Kelley, Paula Peyrani, Jose Bordon, Rodrigo Cavallazzi, Julio A. Ramirez

The University of Louisville Journal of Respiratory Infections

The goals of this study were to investigate the relationship of systemic and local cytokine responses with time to clinical stability (TCS) in patients with community-acquired pneumonia (CAP) and to develop a model to integrate multiple cytokine data into “cytokine response profiles” based on local vs. systemic and pro- vs. anti-inflammatory cytokine patterns in order to better understand their relationships with measures of CAP severity and outcomes. Forty hospitalized patients enrolled through the Community Acquired Pneumonia Inflammatory Study Group (CAPISG) were analyzed. Based on the ranked distribution of the levels of eight different pro-inflammatory cytokines and chemokines (IL-1b, IL-6, IL-8, …

Impact Of Temperature Relative Humidity And Absolute Humidity On The Incidence Of Hospitalizations For Lower Respiratory Tract Infections Due To Influenza, Rhinovirus, And Respiratory Syncytial Virus: Results From Community-Acquired Pneumonia Organization (Capo) International Cohort Study, Timothy L. Wiemken, William A. Mattingly, Stephen P. Furmanek, Brian E. Guinn, Connor L. English, Ruth Carrico, Paula Peyrani, Julio A. Ramirez

The University of Louisville Journal of Respiratory Infections

Abstract

Background: Transmissibility of several etiologies of lower respiratory tract infections (LRTI) may vary based on outdoor climate factors. The objective of this study was to evaluate the impact of outdoor temperature, relative humidity, and absolute humidity on the incidence of hospitalizations for lower respiratory tract infections due to influenza, rhinovirus, and respiratory syncytial virus (RSV).

Methods: This was a secondary analysis of an ancillary study of the Community Acquired Pneumonia Organization (CAPO) database. Respiratory viruses were detected using the Luminex xTAG respiratory viral panel. Climate factors were obtained from the National Weather Service. Adjusted Poisson regression models with robust …

Predicting 30-Day Mortality In Hospitalized Patients With Community-Acquired Pneumonia Using Statistical And Machine Learning Approaches, Timothy L. Wiemken, Stephen P. Furmanek, William A. Mattingly, Brian E. Guinn, Rodrigo Cavallazzi, Rafael Fernandez-Botran, Leslie A Wolf, Connor L. English, Julio A. Ramirez

The University of Louisville Journal of Respiratory Infections

Background: Predicting if a hospitalized patient with community-acquired pneumonia (CAP) will or will not survive after admission to the hospital is important for research purposes as well as for institution of early patient management interventions. Although population-level mortality prediction scores for these patients have been around for many years, novel patient-level algorithms are needed. The objective of this study was to assess several statistical and machine learning models for their ability to predict 30-day mortality in hospitalized patients with CAP.

Methods: This was a secondary analysis of the University of Louisville (UofL) Pneumonia Study database. Six different statistical and/or machine …

Week Of May 22, 2017, New York Medical College

InTouch

• New York Medical College and the Westchester Medical Center Health Network Host Ceremonial Signing of Academic Affiliation Agreement
• Touro College Set to Launch Nursing Program at New York Medical College
• SOM Class of 2020 Honors First Patients at the 29th Annual Convocation of Thanks
• SHSP Hosts Successful Fifth Annual Research and Scholarship Day
• College Celebrates Longevity of Employee Service
• Jeffrey Aston, School of Medicine Class of 2017, Completes Prestigious AOA Fellowship
• Four SHSP Students Graduate from the Westchester Institute for Human Development LEND Program
• NYMC Observes World Hypertension Day

A 49-Year-Old Woman With Chronic Skin Lesions, Acute Mental Status Changes And New Pulmonary Infiltrate: Case Discussion From The University Of Louisville Hospital, Bhavani Puskur, Youssef Khafateh, Srikant Ramachandruni, Veronica Corcino, Mark Burns, Forest W. Arnold

The University of Louisville Journal of Respiratory Infections

No abstract provided.

Alternatives To Pretrial Detention:Pre Global Best Practice Catalog, Jerry Cho, Sara Cronqvist, Sara Curran, Laura Galeano, Camila Jimenez Lugo, Alexandra Lynn, Weronika Kozyra, Justyna Maksimiuk, Suchaya Mokkhasen, Kelly Ortega, Kartika Rahman, Ashley Roman

Publications and Research

This Global Best Practice Catalog of Alternatives to Pretrial Detention was completed by students of the Master of Arts Degree Program in International Crime and Justice at John Jay College of Criminal Justice as part of their capstone course, in collaboration with the US State Department's Diplomacy Lab program. This catalog is intended to cover best practices in reducing pretrial detention (either before it occurs or while it is occurring) across the globe, including laws, policies and programs. It does not include Oceania or very detailed information on North America. Each entry meets 5 of 8 criteria below, as decided …

Modeling Hiv Dynamics Following 3bnc117 Antibody Infusion, Samantha Erwin

Biology and Medicine Through Mathematics Conference

No abstract provided.

Methods For Parameter Estimation Of A Stochastic Seir Model, Kaitlyn Martinez

Biology and Medicine Through Mathematics Conference

No abstract provided.

Applied Drug Development And Combinatorial Strategies For Antimicrobial Treatment, Steven K. Lai Hing

Andrews Research Conference

Streptococcus mutans JH1140 is a strain of bacteria which produces a lantibiotic product, named mutacin 1140. Mutacin 1140 has been shown to be effective at inhibiting Gram-positive bacterial infections caused by Staphylococcus aureus and Streptococcus pneumoniae. Mutacin 1140 is a ribosomally synthesized peptide antibiotic that undergoes extensive posttranslational modifications (PTM). We have found that Mutacin 1140 and an aminoglycoside, Kanamycin, when combined together, act synergistically against Staphylococcus aureus. This was determined by performing serial kill curve dilution overlays on solid media, followed up with kill curve by microdilution plate, and most recently confirmed with kill curve CFU count plates …

Environment, Host And Pathogen Diversity On Probability Of Disease Extinction, Linda Allen

Biology and Medicine Through Mathematics Conference

No abstract provided.

Development Of Standard Operational Procedures For Bacterial Management In Marine Fish Hatcheries, Muyassar H. Abualreesh

Open Access Theses

Live feeds are utilized in marine fish hatcheries to feed and promote the health of finfish larvae due to their nutritional advantages. The presence of detrimental bacteria in rotifer culture can cause disease outbreaks in larval rearing. Nevertheless, the use of UV application to disinfect seawater is not very effective to eliminate and inactivate all pathogenic agents presented in the raw surface water. To investigate new methods of disinfection, two experiments were conducted at the University of Miami Experimental Hatchery (UMEH) to quantify and test for antibiotic susceptibility for Vibrio spp. and the total coliforms by using plate counting method …

Gavage Program For The Preterm Infant, Amanda K. Guina

Master's Projects and Capstones

Preterm infants in the Neonatal Intensive Care unit, are susceptible to hospital acquired infections due to their immature immune systems. To mitigate this occurrence a change project will be implemented to decrease the incidence of nosocomial infection in this population. The project will be focusing on preterm infants working on full nipple feeds. Our project is aiming to discharge this population home with a nasogastric tube to work on feedings, rather than remaining in the hospital. Chart Audits were conducted pre-program and found approximately 18 patients acquired blood stream infections and 2 acquired MRSA. The method used to assist in …