Digital Commons Network^™

Racial And Socioeconomic Disparities Are More Pronounced In Inflammatory Breast Cancer Than Other Breast Cancers, Ryan A. Denu, John M. Hampton, Adam Currey, Roger T. Anderson, Rosemary D. Cress, Steven T. Fleming, Joseph Lipscomb, Xiao-Cheng Wu, J. Frank Wilson, Amy Trentham-Dietz

Epidemiology and Environmental Health Faculty Publications

Inflammatory breast cancer (IBC) is a rare yet aggressive form of breast cancer. We examined differences in patient demographics and outcomes in IBC compared to locally advanced breast cancer (LABC) and all other breast cancer patients from the Breast and Prostate Cancer Data Quality and Patterns of Care Study (POC-BP), containing information from cancer registries in seven states. Out of 7,624 cases of invasive carcinoma, IBC and LABC accounted for 2.2% (N = 170) and 4.9% (N = 375), respectively. IBC patients were more likely to have a higher number (P = 0.03) and severity (P …

Perceptions Of Registered Nurses On The Choice Of Geriatric Nursing As A Specialty Area Of Practice: A Case Study, Cirila Daaco Negad

CUP Ed.D. Dissertations

The progressive growth of geriatric facilities as valuable element of the health system signified for increased services from health care workers particularly Registered Nurses (RNs). A major health care concern could be perceived due to the inadequate number of RNs providing care to elderly patients. Most studies centered on insufficiency of RNs in hospital settings while only few focused on geriatric facilities. In response to this gap, my study concentrated on perceptions of Registered Nurses on the demand for more RNs working with elderly patients in geriatric facilities with specialization in geriatric nursing. My study was a qualitative, descriptive, case …

Reduced Immune Investment With Energy Stress: Evidence From A Mouse Model And Human Studies, Alaina L. Schneider

Theses and Dissertations

During periods of energy stress, animals will prioritize and allocate energy from non-essential to essential tasks. Using a mouse model and published human data, we found that during periods of energy stress, energy is allocated away from immune function, and is prioritized for physical activity usage.

Buford Joins Center For Exercise Medicine As Associate Director, Christina Crowe

Browse All News

No abstract provided.

Age Differences In Stress And Coping: Problem-Focused Strategies Mediate The Relationship Between Age And Positive Affect, Yiwei Chen, Yisheng Peng, Huanzhen Xu, William H. O'Brien

Psychology Faculty Publications

The present study examined the different types of stressors experienced by adults of different ages, their coping strategies, and positive/negative affect. A mediation hypothesis of coping strategies was tested on the relationships between age and positive/negative affect. One-hundred and ninety-six community-dwelling adults (age range 18-89 years old) reported the most stressful situation they experienced in the past month and coping strategies. Levels of positive and negative affect in the past month were also measured. Content analysis revealed age differences in different types of stressors adults reported. Three types of coping strategies were found: problem-focused, positive emotion-focused, and negative emotion-focused coping. …

Protecting The Environment: Awareness And Responsibility, Susan E. Mason, James J. Winkelman

Journal of Vincentian Social Action

Protecting the environment is not only the right thing to do, it is the smart thing to do, in terms of both short-term and long term business goals. Green businesses can realize immediate financial benefits from environmental sustainability and energy conservation, and there are branding benefits associated with developing and maintaining a reputation for integrity and social responsibility. All participants first answered demographic questions and then responded to a ten-item questionnaire, which was a modified version of Simpson’s (1998) environmental awareness questionnaire. In conclusion, the study revealed gender, age, and political affiliation difference in environmental awareness.

The Impact Of Intergenerational Projects On The Younger Person's View Of Older People, Ian Mcnamara

Journal of Social Care

Intergenerational projects and activities have become popular among both youth and senior citizen groups across Ireland. These programmes fill a variety of personal and societal needs as our society becomes increasingly age-segregated. This study examined the impact of intergenerational projects on a group of six girls aged 15 to 16 living in the west of Ireland. It explores preconceptions and changes in views towards older people, as well as personal impacts. All participants were members of a local youth group and had taken part in two intergenerational projects at a local nursing home. The first project involved working with residents …

Bridging The Gap: An Integrated Approach To Facilitating Foundational Learning Of Neuroanatomy And Neurophysiology In Graduate-Level Speech-Language Pathology Coursework, Lisa A. Vinney, Jennine M.T. Harvey

Teaching and Learning in Communication Sciences & Disorders

The current study examined whether the integration of foundational neuroanatomy and neurophysiology content, across a pair of medically-based, disorder-specific courses (motor speech disorders and aphasia), promoted students’ abilities to describe common neurological constructs and apply them to clinical cases. Specifically, student responses to case questions were rubric-scored following their completion of five neuroanatomy and neurophysiology online modules independently and after in-class instructional augmentation of each module’s content. Students’ own perceptions of this integrated curriculum were also surveyed and coded into themes. Rubric scores, evaluating content knowledge of the brainstem, spinal cord, and the neuron, significantly improved from post-module to after …

Sepsis, Sarah Jones

Nursing Student Class Projects (Formerly MSN)

Sepsis is a dysregulation of the inflammatory response, termed systemic inflammatory response syndrome or SIRS, caused by stimulation of an infectious process. Sepsis often leads to organ dysfunction and increased morbidity, mortality and financial burdens. The goal of treatment is to initiate appropriate antimicrobial therapies, target the underlying infection, optimize intravascular volume, provide fluid resuscitation and maintain adequate perfusion and stroke volume (Taeb, Hooper & Marik, 2017).

Timing of treatment and early detection of sepsis is critical to patients with early warning signs. Sharing this information and potentially making a difference in the outcomes of patients presenting with early signs …

Hepatotoxicity Effects Of Alcohol Consumption During Paracetamol Therapy Of Malaria Patients, Fonny Dinge, Sofa D. Alfian, Rizky Abdulah, Sri A. Sumiwi

Pharmacology and Clinical Pharmacy Research

The risk of paracetamol induced hepatotoxicity could increase with alcohol consumption.
Paracetamol was usually given to tropical malaria patients to treat fever. The aim of this study
was to determine the hepatotoxicity effect of alcohol consumption in malaria tropica patients
receiving paracetamol. This study was a cross-sectional study which was conducted during
April-June 2015 at a hospital in Jayapura, Indonesia. The data were obtained from questionnaires
and medical records. Alcohol status was determined by Short Michigan Alcoholics Screening
Test (SMAST) questionnaire. Level of ALT, AST and bilirubin were observed before and after
receiving paracetamol therapy for 5 days. Based on …

The Drug Overdose Epidemic: Deaths Of Despair Or Deaths Of Addiction?, Marissa Botelho, Jennifer Lemos, Jessica Souza, Roger Clark

Sociology Between the Gaps: Forgotten and Neglected Topics

No abstract provided.

A Novel Mechanism Of Non- Feminizing Estrogens In Neuroprotection, Elizabeth B. Engler-Chiurazzi, Douglas F. Covey, James W. Simpkins

Clinical and Translational Science Institute

Estrogens are potent and efficacious neuroprotectants both in vitro and in vivo in a variety of models of neurotoxicity. We determined the structural requirements for neuroprotection in an in vitro assay using a panel of more than 70 novel estratrienes, synthesized to reduce or eliminate estrogen receptor (ER) binding. We observed that neuroprotection could be enhanced by as much as 200-fold through modifications that positioned a large bulky group at the C2 or C4 position of the phenolic A ring of the estratriene. Further, substitutions on the B, C or D rings either reduced or did not markedly change neuroprotection. …

Alzheimer's Disease, Kirstin Fortune

Nursing Student Class Projects (Formerly MSN)

This presentation is an overview on Alzheimer's disease. Signs, symptoms, pathophysiology and pharmaceuticals are all incorporated in this poster. The United States is planning to address the possible crisis of Alzheimer's with many initiatives.

Enduring Chronic Kidney Disease: An Investigation Of Psychosocial Factors And Life Satisfaction In Older Adults Receiving Dialysis Treatment, Bailee Sobotka

Honors Program: Senior Projects (Public)

Chronic kidney disease is a condition during which the kidneys begin to shut down and no longer filter blood efficiently. Once the disease has progressed far enough, dialysis treatments are mandatory to sustain life. To further understand how older adults receiving dialysis treatments cope with their disease, psychosocial factors were evaluated to investigate possible correlations with life satisfaction using a Life Satisfaction Index Z (LSI-Z). Expected correlations with life satisfaction were sociability, financial satisfaction, importance of spirituality, and activities of daily living scores. Interviews were conducted with 30 dialysis patients and results were analyzed using various statistical measures. Significant correlations …

Screening For Traumatic Brain Injury During Mental Health Evaluations, Onome Okurume

Student Projects for Graduate Degrees

Traumatic brain injuries (TBIs) are a major cause of mortality and long-term functional impairment (Gould, Ponsford, Johnston, & Schonberger, 2011; Whelan-Goodinson, Ponsford, Johnston, & Grant, 2009) and are associated with new-onset or worsening of many psychiatric disorders (Gould et al., 2011; Juengst, Whyte, & Skidmore, 2014; Masel & DeWitt, 2010; Whelan-Goodinson et al., 2009) including depression, anxiety, and post-traumatic stress (PTSD). Affected patients may also experience personality changes and problems with aggressive behavior, which can negatively influence personal relationships, ability to work and overall quality of life. This screening can help identify a past TBI, which may influence current mental …

Caregiver Integration During Discharge Planning For Older Adults To Reduce Resource Use: A Metaanalysis, Juleen Rodakowski, Philip Rocco, Maqui Ortiz, Barbara Folb, Richard Schulz, Sally C. Morton, Sally Caine Leathers, Lu Hu, A. Everette James

Political Science Faculty Research and Publications

Objectives

To determine the effect of integrating informal caregivers into discharge planning on postdischarge cost and resource use in older adults.

Design

A systematic review and metaanalysis of randomized controlled trials that examine the effect of discharge planning with caregiver integration begun before discharge on healthcare cost and resource use outcomes. MEDLINE, EMBASE, and the Cochrane Library databases were searched for all English‐language articles published between 1990 and April 2016.

Setting

Hospital or skilled nursing facility.

Participants

Older adults with informal caregivers discharged to a community setting.

Measurements

Readmission rates, length of and time to post‐discharge rehospitalizations, costs of postdischarge …

The Effect Of Different Resistance Training Load Schemes On Strength And Body Composition In Trained Men, Charles Ricardo Lopes, Marcelo Saldanha Aoki, Alex Harley Crisp, Renê Scarpari De Mattos, Miguel Alves Lins, Gustavo Ribeiro Da Mota, Brad Jon Schoenfeld, Paulo Henrique Marchetti

Publications and Research

The purpose of this study was to evaluate the impact of moderate-load (10 RM) and low-load (20 RM) resistance training schemes on maximal strength and body composition. Sixteen resistance-trained men were randomly assigned to 1 of 2 groups: a moderate-load group (n = 8) or a low-load group (n = 8). The resistance training schemes consisted of 8 exercises performed 4 times per week for 6 weeks. In order to equate the number of repetitions performed by each group, the moderate load group performed 6 sets of 10 RM, while the low load group performed 3 sets of 20 RM. …

2017-2018 Undergraduate And Graduate Catalog, The University Of Alabama In Huntsville

Course Catalogs

No abstract provided.

Mitochondrial D-Loop Markers And Size Variation Of Sorex Species, Joseph Andrew Osei

Theses, Dissertations and Culminating Projects

Sorex hoyi share similar morphologies with various other shrew species, ranging from nose size to tail length, which makes identification between species difficult. Current species identification relies on specific morphological traits (including dentition), however due to hybridization, these techniques may be inaccurate in certain shrews. Dentition also requires lethal sampling of shrews, which would best be avoided to not impact the populations.

To remedy this problem, a procedure for identifying the species using the mitochondrial D-loop sequences of Sorex hoyi, Sorex cinereus, Sorexfumeus, Cryptotis parva. and Blarina brevicauda was designed. This procedure would look for speciesspecific differences in the shrews' …

Comparing Reaction Time And Postural Stabilization Based On Activity Groups In Older Adults, Lauren Marie Merk

Graduate Theses and Dissertations

The purpose of this study was to compare reaction time and postural stabilization between activity groups in older adults. These variables are important because older adults are at a high fall risk and two major contributors to fall risk are postural stabilization and reaction time. This study examined if the activity group of an older adult had any influence on reaction time and postural stabilization. Fifty-nine older adults aged 66.46 ± 9.47 years old were used in the study. Thirteen subjects were in the master’s athletes which are individuals over the age of 40 who competed in a nationally sanctioned …

Using Neonatal Skin To Study The Developmental Programming Of Aging, Leryn J. Reynolds, Brett J. Dickens, Benjamin B. Green, Carmen J. Marsit, Kevin J. Pearson

Pharmacology and Nutritional Sciences Faculty Publications

Numerous studies have examined how both negative and positive maternal exposures (environmental contaminants, nutrition, exercise, etc.) impact offspring risk for age-associated diseases such as obesity, type 2 diabetes, hypertension, and others. The purpose of this study was to introduce the foreskin as a novel model to examine developmental programming in human neonates, particularly in regard to adipogenesis and insulin receptor signaling, major contributors to age-associated diseases such as obesity and diabetes. Neonatal foreskin was collected following circumcision and primary dermal fibroblasts were isolated to perform adipocyte differentiation and insulin stimulation experiments. Human neonatal foreskin primary fibroblasts take up lipid when …

Effects Of Adaptive-Tempo Music-Based Ras For Parkinson’S Disease Patients, Bart Moens, Leon Van Noorden, Wim De Wilde, Micheline Lesaffre, Dirk Cambier, Dobromir Dotov, Patrick Santens, Jana Blomme, Heleen Soens, Marc Leman

Journal Articles

The use of Rhythmic Auditory Stimulation (RAS) is a potential method to help Parkinson Patients improve their gait characteristics. By providing auditory stimuli such as a metronome or music, gait impairments, which characterize the illness, tend to improve without pharmacological or surgical intervention. This work evaluates three different RAS approaches: fixed-tempo metronomes, fixed-tempo music and adaptive-tempo music. 29 Parkinson Disease (PD) patients were tested in a repeated measures experiment to compare spatiotemporal gait parameters in different cueing conditions. Baseline measures without RAS were taken, followed by counterbalanced trials of the three RAS methods. Compared to the baseline, beneficial effects were …

Pro-Angiogenesis Therapy And Aging: A Mini-Review, Charles T. Ambrose

Microbiology, Immunology, and Molecular Genetics Faculty Publications

Apart from major illnesses and chronic afflictions, the elderly experience lesser ailments, such as muscle weakness, cold intolerance, and transient memory lapses. Physical signs in the aged include wrinkled skin and the slow healing of skin abrasions. These ailments and signs are grouped together because they may be due in part to an age-linked, waning microcirculation. A reduced capillary density (CD) throughout the body of aged people and animals has been reported in over 40 papers. The reduced CD is due in turn to declining levels of angiogenic growth factors (AGFs) throughout the body during old age, as documented in …

Longitudinal Examination Of Social And Environmental Influences On Motivation For Physical Activity, Elizabeth Richards, M Mcdonough, R Fu

School of Nursing Faculty Publications

Background: Physical activity behavior is influenced by numerous factors including motivation, social interactions, and the walkability of the environment. Aim: To examine how social contexts and environmental features affect physical activity motivational processes across time. Methods: Participants (N=104) completed 3 monthly online surveys assessing self-determination theory constructs, social partners in physical activity, neighborhood walkability, and weekly physical activity. Longitudinal path analysis examined the degree to which physical activity was predicted by individual goals, orientation, and autonomy support and whether these associations were meditated by motivation and moderated by the social and environmental contexts of physical activity. Results: The effect …

2017-2018 Fall Bulletin Amended, University Of Mississippi Medical Center

Bulletins/Catalogs

2017-2018 Fall Bulletin amended

Service-Learning Times : Programme Booklet 2017/18 Semester 1, Office Of Service-Learning, Lingnan University

S-L Times

Service-Learning (S-L) integrates academic study with meaningful community service to create opportunities for students and staff to make positive impact locally, regionally, and globally. In line with Lingnan’s motto “Education for Service”, Service-Learning and Research Scheme (SLRS) aims to provide opportunities where students can apply subject-specific knowledge to the real world, while collaboration partners can benefit from the knowledge and innovation that faculty and students bring to these projects.

Innovation and entrepreneurship are central to SLRS as it is a priority for liberal arts students to understand and engage with the impact of technology on the humanities, and vice versa. …

Optimization Of Mitochondrial Isolation Techniques For Intraspinal Transplantation Procedures, Jenna L. Gollihue, Samir P. Patel, Charles B. Mashburn, Khalid C. Eldahan, Patrick G. Sullivan, Alexander G. Rabchevsky

Physiology Faculty Publications

Background—Proper mitochondrial function is essential to maintain normal cellular bioenergetics and ionic homeostasis. In instances of severe tissue damage, such as traumatic brain and spinal cord injury, mitochondria become damaged and unregulated leading to cell death. The relatively unexplored field of mitochondrial transplantation following neurotrauma is based on the theory that replacing damaged mitochondria with exogenous respiratory-competent mitochondria can restore overall tissue bioenergetics.

New Method—We optimized techniques in vitro to prepare suspensions of isolated mitochondria for transplantation in vivo. Mitochondria isolated from cell culture were genetically labeled with turbo-green fluorescent protein (tGFP) for imaging and tracking purposes …

Primetimes Newsletter, Fall 2017, Office Of Lifespan Studies

PrimeTimes Newsletter

PrimeTimes is the newsletter of the Office of Lifespan Studies in the College of Science at Coastal Carolina University.

August 2017 Commencement Program, Bowling Green State University

Commencement Programs

No abstract provided.

Lhuft Bibliography January 2017, Anne M. Casey, William Condon

Bibliographies

No abstract provided.