Digital Commons Network^™

Incorporating Community-Based Observing Networks And Systems: Enhancing Community Preparedness And Response To Arctic Critical Events, Lilian Alessa, Paula Williams, Andrew Kliskey, Grace Beaujean

Washington Journal of Environmental Law & Policy

No abstract provided.

Assessment Of Tick Antioxidant Responses To Exogenous Oxidative Stressors And Insight Into The Role Of Catalase In The Reproductive Fitness Of The Gulf Coast Tick, Amblyomma Maculatum, D. Kumar, K. Budachetri, V.C. Meyers, Shahid Karim

Faculty Publications

As obligate blood‐sucking ectoparasites, to avoid tissue damage, ticks must neutralize the reactive oxygen species (ROS) generated from uptake and digestion of a bloodmeal. Consequently, ticks utilize a battery of antioxidant molecules, including catalase (CAT), an enzyme that converts hydrogen peroxide (H₂O₂) into water and oxygen. Here, we investigated the tick antioxidant machinery by exogenous injection of sublethal doses of H₂O₂ or paraquat. The relative transcript levels of selected Amblyomma maculatum antioxidant targets in tissues were determined by quantitative reverse transcriptase PCR following treatment. The results showed 2–16‐fold increases in target antioxidant gene …

Biological Sciences Newsletter - June 2016, Department Of Biological Sciences, East Tennessee State University

Biological Sciences Newsletters

No abstract provided.

A Rhetorical Criticism Of Blackfish: Making Waves In Orca Activism, Lindsay Beisheim

Communication Studies

No abstract provided.

Widening Access In Selection Using Situational Judgement Tests: Evidence From The Ukcat, Filip Lievens, Fiona Patterson, Jan Corstjens, Stuart Martin, Sandra Nicholson

Research Collection Lee Kong Chian School Of Business

Widening access promotes student diversity and the appropriate representation of all demographic groups. This study aims to examine diversity-related benefits of the use of situational judgement tests (SJTs) in the UK Clinical Aptitude Test (UKCAT) in terms of three demographic variables: (i) socioeconomic status (SES); (ii) ethnicity, and (iii) gender. Methods: Outcomes in medical and dental school applicant cohorts for the years 2012 (n = 15 581) and 2013 (n = 15 454) were studied. Applicants' scores on cognitive tests and an SJT were linked to SES (parents' occupational status), ethnicity (White versus Black and other minority ethnic candidates), and …

Sediment Transport Dynamics In The Swash Zone Under Large-Scale Laboratory Conditions, Andrea Ruju, Daniel Conley, Gerd Masselink, Jack Puleo

School of Biological and Marine Sciences

No abstract provided.

Strategic Interactions In A One-Sector Growth Model, Eric Fesselmeyer, Leonard J. Mirman, Marc Santugini

Research Collection College of Integrative Studies

We study the effect of dynamic and investment externalities in a one-sector growth model. In our model, two agents interact strategically in the utilization of capital for consumption, savings, and investment in technical progress. We consider two types of investment choices: complements and substitutes. For each case, we derive the equilibrium and provide the corresponding stationary distribution. We then compare the equilibrium with the social planner's solution.

Victorian Teacher Supply And Demand Report 2012 And 2013, Paul R. Weldon, Chandra Shah, Glenn Rowley

School and system improvement

This report provides forecasts of the supply and demand for teachers in Victoria from 2014 to 2020. The teaching workforce includes all teachers from K to 12. This is the tenth in the series of such reports, the first of which was released in 2001. Unlike previous reports, this one includes a section on Early Childhood and has more extensive analysis of the future demand for teachers in the state.

June 2016 News Releases, University Of Montana--Missoula. Office Of University Relations

University of Montana News Releases, 1928, 1956-present

No abstract provided.

Development And Evaluation Of Matrix Material Formulations For Potential Integration Into Immunodiagnostic Biosensors, Payam Aminayi

Dissertations

This study supports the development, characterization and optimization of biosensor material formulations for immunodiagnostic applications based on experimental findings and hypotheses by Wang and Wu [1, 2], and using a test-plate apparatus and thin-film design developed by Young [3].

Certain biosensors working on the basis of conductance/impedance changes have demonstrated their potential to detect various bacteria, enzymes, and biomolecules due to their enhanced electrical properties with incorporated single-walled carbon nanotubes (SWNT). From the work conducted in our laboratory, we are attempting to determine and develop a matrix formulation containing highly dispersed SWNT, antibody and other components that elicit a significantly …

Valorization Of Waste Sludge, S. Shrihari

Manipal Journal of Science and Technology

The amount of sludge produced in wastewater treatment plants is enormous. This sludge contains undesirable metals and other contaminants, and its disposal is expensive. Several attempts are being made towards valorization of this sludge, by using it in building and construction materials, reuse as adsorbent in water and wastewater treatment, as a coagulant and recovery of metals. This paper looks into some of the attempts at valorization of sludge.

Genome-Wide Differentiation In Closely Related Populations: The Roles Of Selection And Geographic Isolation, Rebecca Safran, Elizabeth Scordato, Matt Wilkins, Joanna K. Hubbard, B. R. Jenkins, Tomáš Albrecht, Samuel Flaxman, H. Karaardiç, Yoni Vortman, Arnon Lotem, Patrik Nosil, P. Pap, Sheng-Feng Shen, S.-F. Chan, T. L. Parchman, Nolan C. Kane

School of Biological Sciences: Faculty Publications

Population divergence in geographic isolation is due to a combination of factors. Natural and sexual selection may be important in shaping patterns of population differentiation, a pattern referred to as “isolation by adaptation” (IBA). IBA can be complementary to the well-known pattern of “isolation by distance” (IBD), in which the divergence of closely related populations (via any evolutionary process) is associated with geographic isolation. The barn swallow Hirundo rustica complex comprises six closely related subspecies, where divergent sexual selection is associated with phenotypic differentiation among allopatric populations. To investigate the relative contributions of selection and geographic distance to genome-wide differentiation, …

Aristotle, The Pythagoreans, And Structural Realism, Owen Goldin

Philosophy Faculty Research and Publications

Aristotle’s main objection to Pythagorean number ontology is that it posits as a basic subject what can exist only as inherent in a subject. I then show how contemporary structural realists posit an ontology much like that of Aristotle’s Pythagoreans. Both take the objects of knowledge to be structure, not the subject of structure. I discuss both how pancomputationalists such as Edward Fredkin approach the Pythagorean account insofar as on their account all reality can in principle be expressed as one (very big) number, made up of discrete units, and even more moderate varieties of structural realism, like that of …

The Arg59trp Variant In Angptl8 (Betatrophin) Is Associated With Total And Hdl-Cholesterol In American Indians And Mexican Americans And Differentially Affects Cleavage Of Angptl3, Robert L. Hanson, Fatjon Leti, Darwin Tsinajinnie, Sayuko Kobes, Sobha Puppala, Joanne E. Curran, Laura Almasy, Donna M. Lehman, John Blangero, Ravi Duggirala, Johanna K. Distefano

School of Medicine Publications

We previously identified a locus linked to total cholesterol (TC) concentration in Pima Indians on chromosome 19p. To characterize this locus, we genotyped >2000 SNPs in 1838 Pimas and assessed association with log(TC). We observed evidence for association with log(TC) with rs2278426 (3.5% decrease/copy of the T allele; P=5.045×10(-6)) in the ANGPTL8 (angiopoietin-like 8) gene. We replicated this association in 2413 participants of the San Antonio Mexican American Family Study (SAMAFS: 2.0% decrease per copy of the T allele; P=0.005842). In a meta-analysis of the combined data, we found the strongest estimated effect with rs2278426 (P=2.563×10(-7)). The variant T allele …

Utility Of Lymphoblastoid Cell Lines For Induced Pluripotent Stem Cell Generation, Satish Kumar, Joanne E. Curran, David C. Glahn, John Blangero

School of Medicine Publications

A large number of EBV immortalized LCLs have been generated and maintained in genetic/epidemiological studies as a perpetual source of DNA and as a surrogate in vitro cell model. Recent successes in reprograming LCLs into iPSCs have paved the way for generating more relevant in vitro disease models using this existing bioresource. However, the overall reprogramming efficiency and success rate remain poor and very little is known about the mechanistic changes that take place at the transcriptome and cellular functional level during LCL-to-iPSC reprogramming. Here, we report a new optimized LCL-to-iPSC reprogramming protocol using episomal plasmids encoding pluripotency transcription factors …

Alternative Functions For The Multifarious Inflammasome, J. Martel, H. C. Lai, Y. F. Ko, J. D. Young, David M. Ojcius

All Dugoni School of Dentistry Faculty Articles

The inflammasome has been mainly studied in innate immune cells in which it senses microbes and cellular damage, and induces secretion of pro-inflammatory cytokines. This process induces an inflammatory response that is critical for the resolution of infections and repair of tissue damage following injury. Recent studies indicate that inflammasome complex formation also participates in many other cellular and physiological processes beyond modulation of inflammation, such as autophagy, metabolism, eicosanoids production, and phagosome maturation.

Mechanism Of Lysine 48 Selectivity During Polyubiquitin Chain Formation By The Ube2r1/2 Ubiquitin-Conjugating Enzyme, Spencer Hill, Joseph S. Harrison, Steven M. Lewis, Brian Kuhlman, Gary Kleiger

College of the Pacific Faculty Articles

Lysine selectivity is of critical importance during polyubiquitin chain formation because the identity of the lysine controls the biological outcome. Ubiquitins are covalently linked in polyubiquitin chains through one of seven lysine residues on its surface and the C terminus of adjacent protomers. Lys 48-linked polyubiquitin chains signal for protein degradation; however, the structural basis for Lys 48 selectivity remains largely unknown. The ubiquitin-conjugating enzyme Ube2R1/2 has exquisite specificity for Lys 48, and computational docking of Ube2R1/2 and ubiquitin predicts that Lys 48 is guided to the active site through a key electrostatic interaction between Arg 54 on ubiquitin and …

Access To Education: Transgender Students In Missouri’S Public Education System, Cailynn Hayter

Missouri Law Review

Although the questions about whether transgender students have a right to use the restrooms of their gender identity in public schools have been centered on moral and religious concerns, this Note does not focus on those aspects. Instead, it focuses on legal precedent and the implications of developing law on the issue in Missouri. The first half of this Note discusses the federal and state legal backgrounds of transgender students’ right to use the restroom of their gender identity, while the second half discusses the need for the Missouri General Assembly to adopt a specific statute protecting this right.

The Use Of Lactic Acid Bacteria To Control The Growth Of Foodborne Pathogens On Fresh-Cut Fruits And Sprout Vegetables, Franca Gabriela Rossi

Master's Theses

Growing consumer awareness of the health benefits associated with fruits and vegetables and demand for easy to prepare products has prompted the development of a wide variety of minimally processed fruits and vegetables. Minimally processed fruits and vegetables are often peeled, cut, or diced which compromise the produces’ natural protective barriers, exposing a nutrient rich medium and providing an ideal environment for the growth of microorganisms, including foodborne pathogens. The germination conditions of sprout vegetables consisting of relatively high temperatures and humidity, low light and abundance of nutrients are also conducive to the proliferation of foodborne pathogens. Recent outbreaks and …

Robotic Overbed Table, Jonathan Lantz

Electrical Engineering

Traditionally overbed tables have simple and cheap designs, yet contain many disadvantages compared to the design proposed in this report. Disabled or bedridden persons, often require the use of a bedside table either in hospital environments or at home. Unfortunately, many modern overbed tables require the user to get out of bed and move in order to adjust and position the table. Incorporating a singlebutton control panel that allows the user to make adjustments and access other features independently, creates more accessible product. Integrated subsystems must control all motors and interfaces with an easy access control panel in order to …

Understanding College Students’ Exam Process In A General Chemistry Course, Angela Willson

Masters Theses

The main way most college chemistry courses assess what a student has learned is through a summative exam. After introductory science courses, such as general chemistry, many students cite poor teaching and disappointing grades in these courses as a reason for dropping out of STEM programs. There has been a lack of qualitative research on students’ experiences of the complete process of taking an exam from start to finish, or the exam process, which includes preparing for an exam, taking an exam, receiving feedback, and responding to feedback after the exam has been graded.

My goal in this exploratory study …

Reversibility Of Apixaban Anticoagulation With A Four-Factor Prothrombin Complex Concentrate In Healthy Volunteers., S Nagalla, Lynda Thomson, Y Oppong, B Bachman, I Chervoneva, Walter K. Kraft

Department of Pharmacology and Experimental Therapeutics Faculty Papers

It was hypothesized that the four-factor prothrombin complex concentrate (4F-PCC) Kcentra 25 unit/kg would reverse impairment of thrombin generation in healthy volunteers dosed with apixaban to steady state. In this randomized, two-period crossover, assessor-blinded trial, 12 healthy subjects received 5 mg apixaban every 12 h. Three h after the fifth dose, four-factor prothrombin complex concentrate (4F-PCC) 25 unit/kg or saline were infused. Serial blood samples were assessed for thrombin generation using PPP-reagent and PPP-reagent low, anti-Xa, PT, and PTT assays. Geometric mean ratio was calculated at 30 min postinfusion, and at 24, 48, and 72 h. Peak thrombin generation was …

Bridging The Justice Gap In Family Law: Repurposing Federal Iv-D Funding To Expand Community-Based Legal And Social Services For Parents, Lisa V. Martin, Stacy Brustin

Faculty Publications

Parents in family court overwhelmingly proceed pro se; however, in child support courtrooms, government attorneys representing the state child support agency frequently play a pivotal role. These attorneys represent the state’s ostensible interests in ensuring that children are financially supported and in preventing welfare dependence; they do not represent individual parents. The outcomes of child support proceedings have profound, long-term constitutional and financial implications for parents, yet litigants rarely understand their rights or the role of the government.

Originally, the goal of state child support enforcement efforts was to recapture the costs of welfare expenditures. In 1990, two-thirds of cases …

#Likeagirl: Realizing The Communicative Potential Of Fourth Wave Feminism, Samantha Keville

Communication Studies

Although the notion of feminism has existed among humanity for centuries, it continues to remain one of the most ambiguous and controversial terms in today's society. Throughout history, there have been numerous efforts enacted among humanity aimed at honing women's rights, typically falling under the categories of first, second, and third wave feminism. Recent discussion has taken place regarding the emergence of a new wave of feminism existing today, known as fourth wave feminism. Fourth wave feminism is a movement characterized by the utilization of technology to enhance feminist ideals. Many companies have developed an association with the feminist movement …

Enhancing Digestibility And Ethanol Yield Of Populus Wood Via Expression Of An Engineered Monolignol 4-O-Methyltransferase, Yuanheng Cai, Kewei Zhang, Hoon Kim, Guichuan Hou, Xuebin Zhang, Huijun Yang, Huan Feng, Lisa Miller, John Ralph, Chang-Jun Liu

Department of Earth and Environmental Studies Faculty Scholarship and Creative Works

Producing cellulosic biofuels and bio-based chemicals from woody biomass is impeded by the presence of lignin polymer in the plant cell wall. Manipulating the monolignol biosynthetic pathway offers a promising approach to improved processability, but often impairs plant growth and development. Here, we show that expressing an engineered 4-O-methyltransferase that chemically modifies the phenolic moiety of lignin monomeric precursors, thus preventing their incorporation into the lignin polymer, substantially alters hybrid aspens’ lignin content and structure. Woody biomass derived from the transgenic aspens shows a 62% increase in the release of simple sugars and up to a 49% increase in the …

Red Rock Lake: A Path Forward, Colette Millard, Edwin Brands

Center for Small Towns

The quality of lake water in West Central Minnesota have a been a growing concern in recent years for both residents and state and local governments. This reports evaluates the water quality for the Red Rock Lake Association by summarizing years of existing reports by Minnesota MPCA, DNR and Douglas County about Red Rock Lake into a user-friendly document for the association and lake community residents. The reports also presented a set of recommendations for improving water quality that individuals residents, the lake association and other stakeholders in the Red Rock Lake can discuss and pursue.

Book Reviews: A Chorus Of Cranes: The Cranes Of North America And The World. Paul A. Johnsgard (With Photographs By Thomas D. Mangelsen, And Drawings And Maps By Paul A. Johnsgard)., John G. Sidle

The Prairie Naturalist

Once again, naturalist and author Paul A. Johnsgard invites us to dance and chorus with cranes, and to appreciate their beauty and links to another species, Homo sapiens. A Chorus of Cranes is about natural history but also is a plea for conservation, which is a common foreword, prologue, preface, and/or epilogue of many wildlife books. It is vintage Paul Johnsgard text from preface to epilogue, words that emerge after a long wade through countless papers and reports, and a prolonged career of observation and reflection in the field. He has beckoned us before to cherish cranes and the natural …

Resource Selection By Black-Backed Woodpeckers (Picoides Arcticus) And American Three-Toed Woodpeckers (P. Dorsalis) In South Dakota And Wyoming, Sean R. Mohren, Mark A. Rumble, Chadwick P. Lehman, Stanley H. Anderson

The Prairie Naturalist

Black-backed woodpeckers (Picoides arcticus, [BBWO]) and American three-toed woodpeckers (P. dorsalis, [ATTW]) are uncommon inhabitants of conifer forests and are sympatric in some areas, including the Black Hills. Both species exhibit genetic characteristics associated with isolated populations, are species of special management concern, and for which data are lacking concerning populations and habitats. We developed resource selection models of forest vegetation within 500 m radius plots (78.5 ha) for BBWOs and ATTWs to provide forest managers with stand-level information to estimate how forest management might affect habitat for these species in the Black Hills. Relative probability of selection by BBWOs …

Missing The Point, Christopher N. Jacques

The Prairie Naturalist

Greetings GPNSS members! I hope summer finds you well and enjoying the Great Plains in some way, whether that be getting your hands dirty with field work, a reprieve from the office, anxiously awaiting the crappie bite at your favorite lake, or taking a much needed vacation. For those who enjoy cooler temperatures, summer heat and humidity are challenging and even the most seasoned field biologists among us are tested when fighting the conditions doing what we are passionate about. I personally prefer the fall and winter seasons, though also look forward to summer because it offers me a break …

The Science Of Open Spaces: Theory And Practice For Conserving Large, Complex Systems. Charles G. Curtin., Michelle L. Hellman, Caleb P. Roberts, Hannah Birge, Zachary Warren, Craig R. Allen

The Prairie Naturalist

The phrase “open spaces,” may bring to mind expansive tracts of prairie, rangeland, or even desert, stretching lonely and unchanged to the horizon. Open spaces also could conjure open oceans or interstitial rural lands between urbanized hubs, dotted with farms, fields, and woodlands. In an abstract sense, open spaces could represent gaps in human understanding or blank spaces on a map. In his book The Science of Open Spaces, landscape ecologist Charles Curtin combines all these perspectives, expanding the definition of “open spaces” to multi-layered and multi-scaled complex systems that are “greater than the sum of their parts.” He populates …