Digital Commons Network^™

Hif1Α-Driven Glycolysis Controls Ifn-Γ Production And Immune Checkpoint Blockade Response In Hypoxic T Cells, Zach Lewis, Hongxing Shen, Oluwagbemiga A. Ojo, Vivian Y. Shi, Haitao Ding, Abdelrahman Yassin, James A. Bonner, Lewis Zhichang Shi

Expo Student Presentations

2026 Spring Expo Poster Presentation

• Biological & Life Sciences

Sex Specific Effects Of Early Life Stress On Blood Pressure Regulation Is Independent Of Arterial Stiffness In Rats, Vanvy Ly, Hiruni M. Aponso, David M. Pollack

Expo Student Presentations

2026 Spring Expo Poster Presentation

• Biological & Life Sciences

Gold & Blue Law Edition, Spring 2026, St. Mary's University - San Antonio, Texas

Gold & Blue Law Edition

This is the Spring 2026 edition of Gold & Blue Law Edition which is St. Mary's University's official School of Law publication.

Remove To Recruit: The Short-Term Efficacy Of Invasive Shrub Removal In A Minnesota Floodplain Forest, Claire S. Wiley

Biology Honors Projects

Within Midwest floodplain forests, there is a lack of long-term studies focusing on native tree recruitment post invasive shrub removal. With interacting threats such as emerald ash borer (Agrilus planipennis), invasive earthworms, and white-tailed deer (Odocoileus virginianus), land managers need particular information about these ecosystems in order to better understand how to protect them. This study aims to explore the efficacy of the removal of Rhamnus cathartica and Lonicera spp. in promoting native tree recruitment within a Minnesota floodplain forest along the Mississippi River. Results revealed that post removal ash (Fraxinus spp.) seedling abundance …

The Highs And Lows Of Life In A Valley: Topographic Controls On Tundra Vegetation In A Warming Arctic, Ruth S. Dunlap

Biology Honors Projects

Topographic heterogeneity structures Arctic plant communities, impacting broader ecosystem responses to climate change. The role of topography in shaping leaf physiological, nutritional, and structural traits in the Arctic is important, yet not well characterized across diverse tundra landscapes. To address these controls, we examined plant community composition and measured leaf traits in a few representative species along a heath-slope-valley gradient in Varanger, Norway. Our results indicated that valleys are more biodiverse, driven by forb and graminoid dominance, whereas slopes and heaths had less diversity with high shrub abundance. Leaf physiology and structural traits did not vary across topographic positions, though …

Instrumental Avoidance Promotes Safety Learning Across Distributed Neural Circuits, Zhenfu Wen, Lihan Cui, Muhammad Badarnee, Kai Zhang, Isabel Moallem, Hannah Mcmanus, Zakiya Atiyah, Joseph Borrelli, Wen Li, L Elliot Hong, Peter Kochunov, Mohammed R Milad

Faculty, Staff and Student Publications

Background: Instrumental avoidance is a coping strategy that plays a critical role in anxiety and trauma-related disorders. Yet, the neural mechanisms supporting instrumental avoidance and its interaction with extinction learning remain incompletely understood.

Methods: Fifty-nine healthy adults completed a two-day fMRI paradigm including Pavlovian threat conditioning, avoidance learning, extinction, and memory recall. Subjective reports measuring the 'fear ratings' for each CS were administered and analyzed across all experimental phases. Neural responses were analyzed using univariate general linear modeling and multivariate pattern analysis with a validated threat/safety decoder. To assess generalizability, the analysis pipeline was repeated in an independent cohort (n=59) …

Multivariate Analysis Of Ecological Diversity In Asian Rodentia In The Context Of Tectonism And Environmental Change, Amanda Peng, Samantha S.B. Hopkins

Geosciences Faculty Publications

The Asian continent is unique for its exceptional biodiversity and position as a biogeographic crossroads, resulting in considerable taxonomic, ecological, and morphological diversity. Asia is also notable for its complex geological and climatic history stemming from the collision of Eurasia with the Indian subcontinent, resulting in uplift of the Himalaya and Tibetan Plateau, which have gone on to influence local and global climatic change over millions of years. The effects of these events on biotic assemblages have not been comprehensively investigated, and consequences for mammalian assemblages are unclear. Asian biodiversity is preserved in a rich and well-studied Cenozoic fossil mammal …

Unpacking Developmental Programming: A Conceptual And Historical Analysis In The Context Of Dohad, Andrea Gretchev, Heide S. Temples, Gillian England-Mason, Deborah Dewey, Sara M. Sarasua, Christopher Farrell, Vivian Haley-Zitlin

Publications

The Developmental Origins of Health and Disease (DOHaD) paradigm posits that early environmental factors may influence a child’s development and long-term health outcomes. Developmental programming (DP) is central to this paradigm, whereby specific early life exposures during critical periods of development are associated with changes to physiological and metabolic pathways, potentially predisposing individuals to disease. However, no standard definition of DP exists, and various terms have been used to describe similar processes. This analysis aimed to develop a conceptual definition for DP to inform interdisciplinary research, education, and practice. Walker and Avant’s eight-step method was employed to analyze the literature, …

Dipl 6277 Global Health Security In A Changing World, Matthew Brown Phd, Mps

Diplomacy Syllabi

This course provides an interdisciplinary survey of global health security at a critical juncture in international health governance. The Spring 2026 semester unfolds against the backdrop of dramatic shifts in U.S. global health policy, including the withdrawal from the World Health Organization, the dismantling of USAID, and the introduction of the "America First Global Health Strategy." These changes, coupled with ongoing threats such as the H5N1 avian influenza outbreak and climate-driven health challenges, create an unprecedented moment for examining the intersection of health and security.

Students will analyze how the reconfiguration of global health architecture affects disease surveillance, pandemic preparedness, …

Celebration Of Scholarship And Creativity Magazine, 2024-2025, University Of Texas At Tyler

Celebration of Scholarship and Creativity Magazine

This annual review is compiled to promote scholarship and document a record of the published and creative works of The University of Texas at Tyler faculty for academic year 2024-2025. Information was compiled from Faculty180©, the university’s platform for faculty activity reporting.

Catholic Studies 2026 Newsletter, Sacred Heart University

Catholic Studies Newsletter

Highlights: The Lilly Network 2025 National Conference -- Bergoglio Lecture -- Center for Catholic Studies Lecture Series -- Warsaw Conference on Social Justice --SYNODAL Conversations in the Diocese -- ESTEEM Program at the Center for Catholic Studies

Vol. 16, Iss. 1

Library Newsletter (2009-present)

No abstract provided.

Use Your Voice, St. Mary's University Theatre Department

Theatre

Use Your Voice is a play devised by Dr. Grace Edgar and her students in the Theatre for Change & Social Justice course at St. Mary's University during the Spring 2026 semester. Acts: Lower the Ceiling; Did You Love Him?; Dad, Let Me in; Cartel Assassination; Two Towns; Paperball of the Past; Whale Noise; The Alysa Liu Moment; Since I Was Little; Lake House; The Dow Right Now; Cobbler

Short Lab Report- Presentation, Wroud Saleh, Yevgeniy Grigoryev

Open Educational Resources

No abstract provided.

Transcultural Headache Medicine: A Framework For Integrating Cultural Contexts Into Headache Science And Care - A Call To Action From The International Headache Society., Mario F. P. Peres, Giancarlo Lucchetti, Homero Vallada, Ivy L. Riso, Georgia K. Westenhofen, Marcelo Moraes Valença, Juliana Ramos De Andrade, K. C. Brennan, Morris Levin, Tsubasa Takizawa, Zhao Dong, Yonggang Wang, Wanakorn Rattanawong, Henry Riyanto Sofyan, Massimo Leone, Freda Dodd-Glover, Hsiangkuo Yuan, Abdulrazaq Albilali, Taoufik Alsaadi, Leonardo Caixeta, Anna P. Andreou, Peter J. Goadsby, Antoinette Maassenvandenbrink, Sait Ashina, Rami Burstein, Patricia Pozo-Rosich, Fayyaz Ahmed, Shuu-Jiun Wang

Department of Jefferson Headache Center Papers and Presentations

Headache disorders are among the most disabling neurological conditions, affecting over 1.5 billion people globally. Despite advances in pharmacological therapies, major inequities persist due to underdiagnosis, undertreatment and limited access to effective care, particularly in low- and middle-income countries. Social determinants of health, including cultural meanings, language and health beliefs, are increasingly recognized as key drivers of disparities in burden, diagnosis and treatment outcomes. Traditional medicine, used by more than 80% of the global population, remains first-line care in many regions and continues to influence therapeutic choices in high-income settings. Major systems such as Ayurveda, Traditional Chinese Medicine, Unani and …

Sensitivity Of Headwater Carbon Storage To Climate Change, Maddie Benello

Earth Sciences Undergraduate Senior Theses

Headwater streams play a critical role in the global carbon cycle, serving as significant sites of carbon storage. While there have been recent efforts to quantify carbon storage in headwater streams in the western United States, there remains limited understanding of both the volume and timescale of carbon storage in northeastern forests which often have extensive logging and agricultural histories. Here, we quantify the carbon stock, residence time, and flux of a zero-to-first order headwater stream in Charles Downer State Forest (DF), VT using novel fallout radionuclide (FRN) chronometry. We find DF headwaters have a carbon stock of 66.2 Mg …

Cuny Oer Initiative Catalog (Ay 2024-2025), Jahanara Alamgir, Yujin Lee-Hwang, Rachael Nevins, Elliot Galvis, Rebecca Morofsky, Andrew Mckinney, Jojo Karlin

Open Educational Resources

This circulating catalog inventories the reusable teaching objects produced by CUNY campuses in AY 2024-2025! You’ll find textbooks, assignments, syllabi, videos, and more, organized by discipline and with brief descriptions of the resource. This publication (which links to all the resources) is supplemented by a by our online, filterable CUNY OER Initiative Catalog.

The CUNY OLS Research and Publishing Strategy team gathered, described and indexed the work of the campuses. OLS Fellow Hwang-Lee Yujin designed the publication.

The Indian River Lagoon Through The Lens Of An Artist: Examining The Impact Of Growth And Development On The Lagoon's Water Quality, Lisa K. Skelly

Theses

This project investigates the ecological degradation of the Indian River Lagoon, a vital estuary on central Florida’s east coast. The research focuses on the intersection of habitat loss and water quality degradation, specifically as they relate to anthropogenic factors such as land development and nutrient pollution. Furthermore, the study evaluates the effectiveness of environmental art in fostering environmentally conscious behavior. I translated these findings into a cohesive body of work, including ceramics, fiber arts, and oil painting, utilizing site-specific materials sourced from the lagoon. By integrating these organic elements, the work aims to showcase the estuary’s natural beauty while highlighting …

A Comparative Study On Performance Of Iot-Driven Ml-Enabled Forecasting Models For Efficient Air Quality Monitoring, Bara Ksiksi

Theses

Air pollution is one of the most critical environmental challenges affecting public health globally, responsible for approximately 4.2 million premature deaths annually according to the World Health Organisation. This thesis presents a comparative study of IoT-driven machine learning forecasting models for air quality monitoring in Abu Dhabi, UAE, introducing a zonal approach combined with satellite-based spatial validation. The primary objective is to evaluate forecasting performance across three distinct activity zones using ground station data from the Environment Agency Abu Dhabi (EAD), and to incorporate a spatial validation component using satellite imagery to assess the consistency of ground-based predictions at a …

A Computational Assessment Of Halobacterium Salinarum Glutamate Dehydrogenase Enzymes, Maaz Abdalla

Theses

Glutamate dehydrogenase (GDH) is a hexameric enzyme. GDH is involved in several pathways and cellular processes such as oxidation-reduction homeostasis, ammonia metabolism, lipid biosynthesis, insulin and lactate production, and acid-base equilibrium. The main objective of this thesis is to understand the structural and biochemical properties of this enzyme and why some organisms, for e.g., Halobacterium salinarum, have more than one GDH with different coenzyme specificities. The catabolism of glutamate is linked to NAD+ specific GDHs, meanwhile, NADP+ specific GDHs play an anabolic role in ammonia assimilation. Molecular docking and binding free energy calculations were employed followed by long-scale (500 nanoseconds) …

Comparative Evaluation Of Five Bacterial Strains For The Fermentation Of Camel Milk, Sifatun Nesa Ali

Theses

In this study, the comparative fermentation performance of lactic acid bacteria Streptococcus thermophilus, Lactobacillus delbrueckii subsp. bulgaricus, Lb. helveticus, Lb. casei, and Lactiplantibacillus plantarum in Camel Milk (CM) and Bovine Milk (BM) was investigated. Fermentations were carried out at 42°C for 48 hours, and was monitored through bacterial growth, titratable acidity, pH evolution, proteolytic activity, microstructural properties, and rheological characteristics. Although comparable bacterial viability was observed in CM and BM, acidification kinetics varied significantly between CM and BM (p < 0.05). Proteolysis was significantly higher in fermented CM than in BM (p < 0.001), with consistently greater o-Phthalaldehyde Assay (OPA) values in CM across all strains during fermentation (p < 0.001). Scanning electron microscopy revealed more porous, loose protein matrices in fermented CM than in BM, which supports the rheological results showing weaker gel networks and lower rheological strength in fermented CM. Among the tested bacteria, Lb. casei demonstrated superior adaptability, enhanced viability, balanced acidification, and favorable rheological properties in both milks. Overall, the results of this thesis demonstrate strain-specific fermentation responses and support the possible suitability of different starter cultures for improving the technological performance of fermented camel milk products.

Optimizing Duckweeds Harvesting Strategies To Maximize Nutrient Recovery And Its Role As A Phytosensor In Different Water Sources While Maintaining Sustainable Biomass Growth, Basma Ghannam

Theses

This thesis is concerned with determining the optimal water treatment and harvesting strategy for Lemna minor duckweed plants. The main objective of this thesis is to examine how duckweed plants grow in terms of biomass, photosynthetic activity, leaf morphology, chlorophyll and carotenoid content, and their efficiency in nutrient removal from different water sources. The methodology of the study included assessing duckweed in three water samples including tap water, saline water, and greywater and three harvesting strategies, including low, medium, and high harvesting intensities to assess their growth and nutrient removal efficiency. The results of the study showed that L. minor …

Breath-Based Detection Of Liver Cancer Biomarkers Using An Swcnt-Fet Nano-Biosensor: Quantumatk, Mohamed Mohieb Rashdan

Theses

Early detection of liver cancer remains limited by the slow pace and invasiveness of current testing methods. This study proposes a single-walled carbon nanotube field-effect transistor (SWCNT-FET) designed to detect hexanal—a volatile organic compound (VOC) elevated in liver cancer—directly from exhaled breath. The device is modeled in QuantumATK using a semi-empirical Extended Hückel Hamiltonian within the non-equilibrium Green's function (NEGF) framework, emphasizing realistic contact physics by employing metallic SWCNT electrodes instead of conventional metal films. Zigzag channels with (11,0) and (12,0) chiralities are examined to analyze how geometry and contact matching influence charge transport. Simulations include current–voltage (I–V) characteristics and …

3-Deoxyanthocyanidins Inhibit Β-Amyloid Aggregation, Toxicity, And Mitochondrial Dysfunction: Evidence From Mc-65 Cells And Molecular Dynamics Simulations, Rasheed A. Abdulraheem, Ammar U. Danazumi, Philipp Nitschke, Luke Gray Whiley, Abdulrahman Ibrahim Tudu, Ranil Coorey, Zhoyu Li, Prashant Bharadwaj, Vijay Jayasena, Stuart K. Johnson, Ralph N. Martins, W. M.A.D.Binosha Fernando

Research outputs 2022 to 2026

Accumulation of amyloid-beta (Aβ42) senile plaques in the brain is a hallmark of Alzheimer's disease (AD). Although some drug have been approvaled recently, none has demonstrated robust disease-modifying outcome. The 3-deoxyanthocyanidins (3-DXA) and their derivatives represent a more stable class of polyphenols, present at uniquely high concentrations in sorghum grains. Although 3-DXA exhibit strong potential to modulate protein aggregation processes, their effects on AD pathology remain unexplored. In this study, we investigated the inhibitory effects of three 3-DXA derivatives, apigeninidin chloride (AC), luteolinidin chloride (LC), and 7-methoxy apigeninidin (7-MAC), on Aβ42 aggregation and associated neurotoxicity. Thioflavin T fluorescence assay was …

Characterising Soil Microbial Communities In Thinned And Unthinned Eucalyptus Forest In Southwestern Australia, Aaron J. Brace, Laurence Dugal, Josephine Hyde, Kristen Fernandes, Anna J.M. Hopkins, Emma Stevens, Gavan S. Mcgrath, Katinka X. Ruthrof

Research outputs 2022 to 2026

Climate change stress in forested ecosystems globally has led to die-off events, and management actions are needed to help mitigate these pressures. Forest thinning has been proposed to reduce competition for moisture between trees, however, the effects of forest thinning on lesser-studied organisms, such as soil microbial communities, need quantification. Soil microbial communities are essential for processes such as nutrient cycling and can be used as indicators of below-ground health and as an overall proxy for biodiversity. This study examined soil microbial communities, and site and soil characteristics, directly at the base of trees and in inter-tree spaces in a …

A Flexible Wearable Glucose Sensor For Noninvasive Diabetes Screening: Functional Equivalence And Model Interpretability, Wenhan Xie, Wang, Hao Liu, Shuo Chen, Peng Wang, Yumei Han, Xianxiang Chen, Zhen Fang, Zhan Zhao, Guohong Zhang, Xiuhua Guo

Research outputs 2022 to 2026

Real-world evidence for wearable noninvasive glucose monitoring (NIGM) remains limited. To evaluate the functional equivalence of a wearable NIGM device and explore its utility for T2DM and prediabetes screening. In this multicenter study, 12-h daytime glucose profiles obtained by a flexible reverse iontophoresis-based electrochemical sensor were compared with capillary glucose using functional equivalence. Subgroup analyses were conducted. Screening models of T2DM and prediabetes were developed using elastic net and Logistic regression. A total of 135 participants (mean age 35.3 years; 60.0% female) were included, and no serious device-related adverse events were reported. Compared to the capillary measurements, functional equivalence was …

Disuse-Induced Muscle Atrophy And Muscle Weakness From Hospitalization To Spaceflight: Exercise Succeeds In Prevention And Treatment—A Meta-Analysis, Camila S. Padilha, Figueiredo, Rafael Deminice, S. Ribeiro, Robert U. Newton, Nicolas H. Hart, José Cesar Rosa-Neto, Marília Seelaender, Fábio Santos Lira

Research outputs 2022 to 2026

Background: Exercise has been proposed as both a preventive and therapeutic countermeasure; however, its effectiveness across different disuse conditions and timings of implementation remains uncertain. Methods: This systematic review and meta-analysis (PROSPERO: CRD42021256599) searched ClinicalTrials.gov, Cochrane Central, PubMed, SPORTDiscus, Web of Science, Scopus, CINAHL and SciELO from inception to May 2021, with an update in March 2025. Randomized and nonrandomized controlled trials examining exercise interventions during or after muscle disuse were included according to the PICOS framework. Random-effects meta-analysis evaluated effects on muscle strength, power and mass across hospitalization, bed rest and spaceflight conditions. Effect sizes (ES) are reported as …

Impact Of Cannabis And Cannabis Legalization On Us Atrial Septal Defect Rates, Albert Stuart Reece, Hulse

Research outputs 2022 to 2026

Atrial septal defect (ASD) affects 1:11.3 children in some US states; however, the antecedents of these trends are yet to be identified. A total of 1882 ASD rates (ASDRs) for 2003–2020 were sourced from the National Birth Defects Prevention Network reports. A total of 406,893 ASDs are reported. Substance (cigarettes, binge alcohol, cannabis, cannabinoids, analgesics, cocaine) exposure data were taken from the National Survey of Drug Use and Health. Income and ethnicity data were derived from the US Census. Adjustment was performed by mixed effects, survey and generalized additive regression. Causal analysis was by inverse probability weighting and E-values. Data …

Space-Time Analysis Of Burgeoning Us Atrial Septal Defect Rates Driven By Cannabis, Albert Stuart Reece, Kenneth Hulse

Research outputs 2022 to 2026

Atrial septal defect (ASD) has become increasingly common in the USA and now affects 1 in 11.3 children in some places, but space–time analysis has not been applied to this emerging trend. ASD rate (ASDR) data were obtained from the National Birth Defects Prevention Network 2003–2020. Substance (cigarettes, alcohol, cannabis, analgesics, cocaine) use data were obtained from the National Survey of Drug Use and Health. Income data were obtained from the US Census. Analysis was limited to the Non-Hispanic White population by technical factors. Time-sequential univariate and bivariate maps were prepared for both covariates and outcomes and their combinations. Spatial …

Upper Ocean Cycling Of Iron South Of The Polar Front: Biological Patterns And Processes, Luis M. Laglera, Santos-Echeandía, Viena Puigcorbé, Christine Klass, Dieter Wolf-Gladrow

Research outputs 2022 to 2026

Samples from the upper 300 m along the 52°S band, south of the Antarctic Polar Front in the Atlantic sector of the Southern Ocean, including a 3-week monitoring of a persistent bloom, were analyzed to advance our understanding of iron cycling and supply to recurrent phytoplankton blooms. We measured dissolved Fe (dFe, <0.2 μm) and labile particulate iron using a mild acid leach (pLFe^48h) targeting primarily detrital and fecal material. Particulate iron was partitioned into size classes to distinguish small, “slow” sinking particles (<53 μm) from large, “fast” sinking particles (>53 μm), while intermediate fractions were analyzed to investigate aggregation and export processes. Across all stations, dFe exhibited a consistent vertical structure, including a previously undescribed …