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Social-Biological Interactions In Oral Disease: A 'Cells To Society' View, Noha Gomaa, Michael Glogauer, Howard Tenenbaum, Arjumand Siddiqi, Carlos Quiñonez

Paediatrics Publications

Oral diseases constitute a major worldwide public health problem, with their burden concentrating in socially disadvantaged and less affluent groups of the population, resulting in significant oral health inequalities. Biomedical and behavioural approaches have proven relatively ineffective in reducing these inequalities, and have potentially increased the health gap between social groups. Some suggest this stems from a lack of understanding of how the social and psychosocial contexts in which behavioural and biological changes occur influence oral disease. To unravel the pathways through which social factors affect oral health outcomes, a better understanding is thus needed of how the social 'gets …

Faculty Senate Agenda, January 11, 2016, Utah State University

Faculty Senate & Faculty Senate Executive Committee

• EPC Items December 2015
• Council on Teacher Education
• Scholarship Advisory Board
• 405.12.1 Annual Review of Faculty (First Reading)

Adsorption And Unfolding Of A Single Protein Triggers Nanoparticle Aggregation, Lydia Kisley

Faculty Scholarship

The response of living systems to nanoparticles is thought to depend on the protein corona, which forms shortly after exposure to physiological fluids and which is linked to a wide array of pathophysiologies. A mechanistic understanding of the dynamic interaction between proteins and nanoparticles and thus the biological fate of nanoparticles and associated proteins is, however, often missing mainly due to the inadequacies in current ensemble experimental approaches. Through the application of a variety of single molecule and single particle spectroscopic techniques in combination with ensemble level characterization tools, we identified different interaction pathways between gold nanorods and bovine serum …

The Utah Statesman, January 11, 2016, Utah State University

The Utah Statesman

Weekly student newspaper of Utah State University in Logan.

Daily Eastern News: January 11, 2016, Eastern Illinois University

January

No abstract provided.

The Complete Sequence And Comparative Analysis Of A Multidrug Resistance And Virulence Multireplicon Incfii Plasmid Pec302/04 From An Extraintestinal Pathogenic Escherichia Coli Ec302/04 Indicate Extensive Diversity Of Incfii Plasmids, W.S. Ho, K.P. Yap, C.C. Yeo, G. Rajasekaram, Kwai Lin Thong

Research Publications (2016 to 2020)

Extraintestinal pathogenic Escherichia coli (ExPEC) that causes extraintestinal infections often harbor plasmids encoding fitness traits such as resistance and virulence determinants that are of clinical importance. We determined the complete nucleotide sequence of plasmid pEC302/04 from a multidrug-resistant E. coli EC302/04 which was isolated from the tracheal aspirate of a patient in Malaysia. In addition, we also performed comparative sequence analyses of 18 related IncFIIA plasmids to determine the phylogenetic relationship and diversity of these plasmids. The 140,232 bp pEC302/04 is a multireplicon plasmid that bears three replication systems (FII, FIA, and FIB) with subtype of F2:A1:B1. The plasmid is …

Human Gut Bacteria Are Sensitive To Melatonin And Express Endogenous Circadian Rhythmicity, Jiffin K. Paulose, John M. Wright, Akruti G. Patel, Vincent M. Cassone

Biology Faculty Publications

Circadian rhythms are fundamental properties of most eukaryotes, but evidence of biological clocks that drive these rhythms in prokaryotes has been restricted to Cyanobacteria. In vertebrates, the gastrointestinal system expresses circadian patterns of gene expression, motility and secretion in vivo and in vitro, and recent studies suggest that the enteric microbiome is regulated by the host’s circadian clock. However, it is not clear how the host’s clock regulates the microbiome. Here, we demonstrate at least one species of commensal bacterium from the human gastrointestinal system, Enterobacter aerogenes, is sensitive to the neurohormone melatonin, which is secreted into the …

University Of Northern Iowa Faculty Senate Meeting Minutes, January 11, 2016, University Of Northern Iowa. Faculty Senate.

Documents - Faculty Senate

Meeting minutes from the Faculty Senate of the University of Northern Iowa.

The Mechanisms Of Water Exchange: The Regulatory Roles Of Multiple Interactions In Social Wasps, Devanshu Agrawal, Istvan Karsai

ETSU Faculty Works

Evolutionary benefits of task fidelity and improving information acquisition via multiple transfers of materials between individuals in a task partitioned system have been shown before, but in this paper we provide a mechanistic explanation of these phenomena. Using a simple mathematical model describing the individual interactions of the wasps, we explain the functioning of the common stomach, an information center, which governs construction behavior and task change. Our central hypothesis is a symmetry between foragers who deposit water and foragers who withdraw water into and out of the common stomach. We combine this with a trade-off between acceptance and resistance …

Site-Specifically Labeled Immunoconjugates For Molecular Imaging—Part 1: Cysteine Residues And Glycans, Pierre Adumeau, Sai Kiran Sharma, Colleen Brent, Brian M. Zeglis

Publications and Research

Due to their remarkable selectivity and specificity for cancer biomarkers, immunoconjugates have emerged as extremely promising vectors for the delivery of diagnostic radioisotopes and fluorophores to malignant tissues. Paradoxically, however, these tools for precision medicine are synthesized in a remarkably imprecise way. Indeed, the vast majority of immunoconjugates are created via the random conjugation of bifunctional probes (e.g., DOTA-NCS) to amino acids within the antibody (e.g., lysines). Yet antibodies have multiple copies of these residues throughout their macromolecular structure, making control over the location of the conjugation reaction impossible. This lack of site specificity can lead to the formation of …

January 11, 2016: New Sustainability Report, Summer Mission Programs, Hands-On Genetics, Saint Mary's College Of California

SMC Bulletin 2013-2020

No abstract provided.

Characterization Of Rna Helicase Csha And Its Role In Protecting Mrnas And Small Rnas Of Staphylococcus Aureus Strain Newman, Samin Kim, Anna-Rita Corvaglia, Stefano Léo, Ambrose Cheung, Patrice Francois

Dartmouth Scholarship

The toxin MazF_sa in Staphylococcus aureus is a sequence-specific endoribonuclease that cleaves the majority of the mRNAs in vivo but spares many essential mRNAs (e.g., secY mRNA) and, surprisingly, an mRNA encoding a regulatory protein (i.e., sarA mRNA). We hypothesize that some mRNAs may be protected by RNA-binding protein(s) from degradation by MazF_sa. Using heparin-Sepharose-enriched fractions that hybridized to sarA mRNA on Northwestern blots, we identified among multiple proteins the DEAD box RNA helicase CshA (NWMN_1985 or SA1885) by mass spectroscopy. Purified CshA exhibits typical RNA helicase activities, as exemplified by RNA-dependent ATPase activity and unwinding of …

The Impact Of Information On Behavior Under An Ambient-Based Policy For Regulating Nonpoint Source Pollution, Haoran Miao, Jacob Fooks, Todd Guilfoos, Kent Messer, Soni M. Pradhanang, Jordan Suter, Simona Trandafir, Emi Uchida

Environmental and Natural Resource Economics Working Papers

Stemming from Segerson [1988], literature on nonpoint source pollution shows that ambient-based regulatory policies can induce polluters in a common watershed to comply with an exogenously determined emissions standard. This study uses laboratory economic experiments in a spatially heterogeneous setting to test the effectiveness of an ambient tax/subsidy policy in a setting with realistic in-stream nutrient transport dynamics when varying levels of ambient information about the pollution is available to the agents and the regulator. We find that increasing the frequency of ambient monitoring improves the spatial allocation of emissions reductions. In particular with more frequent monitoring, the ambient-based policy …

My News

My News (2014-2020)

• Georgia Southern staff honored with Awards of Excellence
• Georgia Southern creates Dr. Willie J. Burden Memorial Scholarship
• New pedestrian crossing at University entrance
• New Health Services facility opens today
• Georgia Southern hosts renowned educator Dr. Steve Perry for annual MLK Celebration

Reduction Of Ctrp9, A Novel Anti-Platelet Adipokine, Contributes To Abnormal Platelet Activity In Diabetic Animals., Wenqing Wang, Wayne Bond Lau, Yajing Wang, Xin-Liang Ma, Rong Li

Department of Medicine Faculty Papers

Platelet hyper-reactivity is a crucial cause of accelerated atherosclerosis increasing risk of thrombotic vascular events in diabetic patients. The mechanisms leading to abnormal platelet activity during diabetes are complex and not fully defined. The current study attempted to clarify the role of CTRP9, a novel adiponectin paralog, in enhanced platelet activity and determined whether CTRP9 may inhibit platelet activity. Adult male C57BL/6 J mice were randomized to receive high-fat diet (HFD) or normal diet (ND). 8 weeks after HFD, animals were sacrificed, and both plasma CTRP9 and platelet aggregation were determined. HFD-fed animals increased weight gain significantly, and became hyperglycemic …

A New Method For The Rapid Analysis Of 1h-Pyrrole-2,5-Diones (Maleimides) In Environmental Samples By Two-Dimensional Gas Chromatography Time-Of-Flight Mass Spectrometry (Gc×Gc-Tof-Ms), S Naeher, Sk Lengger, K Grice

School of Geography, Earth and Environmental Sciences

Maleimides (1H-Pyrrole-2,5-diones) are monopyrrolic pigment derivatives with specific alkyl side chains that can be directly linked to their tetrapyrrole precursors, most notably chlorophylls and bacteriochlorophylls. These compounds can be used as palaeoenvironmental indicators such as, for instance, algal productivity and redox conditions in ancient and modern aquatic systems. Here, we present a new method using two-dimensional gas chromatography time-of-flight mass spectrometry (GC×GC-ToF-MS), which enables the rapid analysis of maleimides in complex mixtures and different matrices (e.g. sediments and soils), therefore largely simplifying the previous intricate maleimide purification protocol. This method also reduces the potential for bias associated with partial losses …

Medical School Watercooler Newsletter - January 10, 2014, Lindsey Lyle

Watercooler Newsletter

This is the January 10, 2014 edition of the Frederick P. Whiddon College of Medicine's newsletter - Watercooler.

Contents Include:

• Two USA Graduate Students Awarded AHA Grants
• January Med School Café - ‘Cosmetic and Reconstructive Breast Surgery’
• Carla Watlington Recognized for Customer Service
• Alice Johnson Named Assistant Administrator for Ancillary Services

Litigating The Blue Wall Of Silence: How To Challenge The Police Privilege To Delay Investigation, Aziz Huq, Richard H. Mcadams

Public Law and Legal Theory Working Papers

No abstract provided.

Three Popular Medicinal Mushroom Supplements: A Review Of Human Clinical Trials, Megan Frost

Faculty Publications

There are many mushroom supplements on the market claiming a variety of health benefits, and it is difficult to discern which of these claims is backed by reliable research. Most of the existing research is conducted using either human cells or animal models rather than human participants. Without being tested directly on humans, this research has limited application. A review of the literature reveals a relatively small number of studies have been conducted using human patients and those that do exist vary widely in study design and quality. This article brings together all the existing studies that involve human participants …

Gene 33/Mig6 Inhibits Hexavalent Chromium-Induced Dna Damage And Cell Transformation In Human Lung Epithelial Cells, Soyoung Park, Cen Li, Hong Zhao, Zbigniew Darzynkiewicz, Dazhong Xu

NYMC Faculty Publications

Hexavalent Chromium [Cr(VI)] compounds are human lung carcinogens and environmental/occupational hazards. The molecular mechanisms of Cr(VI) carcinogenesis appear to be complex and are poorly defined. In this study, we investigated the potential role of Gene 33 (ERRFI1, Mig6), a multifunctional adaptor protein, in Cr(VI)-mediated lung carcinogenesis. We show that the level of Gene 33 protein is suppressed by both acute and chronic Cr(VI) treatments in a dose- and time-dependent fashion in BEAS-2B lung epithelial cells. The inhibition also occurs in A549 lung bronchial carcinoma cells. Cr(VI) suppresses Gene 33 expression mainly through post-transcriptional mechanisms, although the mRNA level of gene …

Phase Transition Enthalpy Measurements Of Organic And Organometallic Compounds. Sublimation, Vaporization And Fusion Enthalpies From 1880 To 2015. Part 1. C1 − C10, William Acree, James Chickos

Chemistry & Biochemistry Faculty Works

A compendium of phase change enthalpies published in 2010 is updated to include the period 1880–2015. Phase change enthalpies including fusion, vaporization, and sublimation enthalpies are included for organic, organometallic, and a few inorganic compounds. Part 1 of this compendium includes organic compounds from C1 to C10. Part 2 of this compendium, to be published separately, will include organic and organometallic compounds from C11 to C192. Sufficient data are presently available to permit thermodynamic cycles to be constructed as an independent means of evaluating the reliability of the data. Temperature adjustments of phase change enthalpies from the temperature of measurement …

A New Species Of Euscorpius Thorell, 1876 From Peloponnese, Greece (Scorpiones: Euscorpiidae, Gioele Tropea, Victor Fet, Aristeidis Parmakelis, Panayiota Kotsakiozi, Iasmi Stathi

Euscorpius

A new scorpion species, Euscorpius (Euscorpius) erymanthius sp. n., is described from Peloponnese, Greece (Erymanthos Mts.), based on genetic and morphological evidence. It is characterized by small size, light brown to reddish color, and a standard trichobothrial pattern (Pv = 8–9, et = 7–6, em = 4 and eb = 4). In a phylogeny based on multiple DNA markers, the new species groups close with E. corcyraeus Tropea et Rossi, 2012 from Corfu (Kerkyra) Island.

A Review Of Androctonus Finitimus (Pocock, 1897), With Description Of Two New Species From Pakistan And India (Scorpiones, Buthidae), František Kovařík, Zubair Ahmed

Euscorpius

We describe Androctonus robustus sp. n. and A. cholistanus sp. n. from Pakistan and India and compare them with A. finitimus (Pocock, 1897), whose holotype we have studied. These three species are closely related and form a group that has hitherto been considered one species. They share coloration and are close to each other in geographic range. However, these three species can be reliably distinguished morphologically, primarily based on morphometry of male metasoma, which is widest in A. robustus sp. n. and narrowest in A. cholistanus sp. n.

A New Species Of Buthus Leach, 1815 From Libya (Scorpiones: Buthidae), Andrea Rossi, Gioele Tropea, Ersen Aydın Yağmur

Euscorpius

Although Libya covers a very wide territory in northern Africa, only two species of the genus Buthus have been recorded from this country: B. tunetanus (Herbst, 1800) and B. barcaeus Birula, 1909. In the present study, a third species, Buthus lourencoi sp. n., closely related to Buthus egyptiensis Lourenço et Cloudsley-Thompson 2012, is described from west Libya, around the area of Tripoli. An identification key for the scorpions of the genus Buthus (Leach, 1815) that occur in Algeria, Tunisia, Libya, and Egypt is provided.

Reproduction And Birth In The “Vorhiesi” Group Of The Genus Vaejovis (Scorpiones: Vaejovidae). Part I. Clutch Size, Richard F. Ayrey

Euscorpius

A total of 2,287 newborn scorpions were counted and photographed on 100 females of all 12 described species of the “vorhiesi” group of the genus Vaejovis (Scorpiones: Vaejovidae) found in Arizona, USA, and several undescribed species. Average clutch size for the “vorhiesi” group and for each individual species is reported. The data clearly shows that the larger species have more young, per parturition, than the smaller species. Representative photographs are presented for each species discussed.

Three More Species Of Euscorpius Confirmed For Greece (Scorpiones: Euscorpiidae), Victor Fet, Michael E. Soleglad, Aristeidis Parmakelis, Panayiota Kotsakiozi, Iasmi Stathi

Euscorpius

In Greece, scorpion genus Euscorpius has been insufficiently studied. Taxonomy of several species and subspecies has been inconsistent and confusing. We provide new morphological data and redescriptions of type specimens of three “old” taxa, described from Greece and formerly listed under a “catch-all” taxon Euscorpius carpathicus. We elevate to, or confirm at species status: Euscorpius scaber Birula, 1900 (type locality: Mt. Athos), E. candiota Birula, 1903 (type locality: Heraklion, Crete), and E. ossae Di Caporiacco, 1950, stat.n. (type locality: Mt. Ossa, Thessaly). Species-level separation of these taxa is also confirmed by multiple species delimitation methods implemented on the phylogenetic …

Etudes On Iurids, Vii. An Sem Study Of External Morphology Of Calchas Birulai Fet Et Al., 2009 (Scorpiones: Iuridae), Mehlika Benli, Ersen Aydın Yağmur, Victor Fet

Euscorpius

External morphology of a recently described scorpion species, Calchas birulai Fet et al., 2009 (Iuridae), was investigated in detail using Scanning Electron Microscopy (SEM). The samples were collected from Halfeti District, Şanlıurfa Province, Turkey. We investigate and depict, in particular, the cuticle, chelicerae, genital operculum, sternum, stigmata, wax pores, and sensory organs (trichobothria, setae, pectines, slit sensilla, constellation array).

Pandinus (Pandinus) Trailini Sp. N. From Ethiopia (Scorpiones: Scorpionidae), With Data On Localities And Life Strategy, František Kovařík

Euscorpius

Pandinus (Pandinus) trailini sp. n. from Ethiopia is described and compared with other species of the subgenus. The new species is characterized by 6/4: 6-7/4: 7-8/4-5: 7-8/4-5 spination formula of tarsomere II and only two spines on the inclined anteroventral surface of tarsomere II; 16–18 ventral trichobothria on the chela; and sexual dimorphism, with the male having a more pronounced tooth on the movable finger of pedipalp than the female. A key to species and a distribution map of the subgenus Pandinus Thorell, 1876 are provided. Presented are also photos of localities.

Reconsideration Of The Taxonomy Of Euscorpius Tergestinus (Scorpiones: Euscorpiidae), Gioele Tropea

Euscorpius

After the revision of Fet & Soleglad (2002), Euscorpius tergestinus (C. L. Koch, 1837) was considered a polymorphic species widespread from France to Croatia. In this study, we reconsidered the taxonomy of E. tergestinus s.str. based on morphological and genetic evidence, its range, and its original description. Euscorpius aquilejensis (C. L. Koch, 1837), stat. nov., previously synonymous with E. tergestinus, is elevated to species status herein. A preliminary phylogenetic analysis based on available GenBank 16S rDNA data shows a separate, basal position of E. aquilejensis and some other Euscorpius species, which implies that the subgenus Euscorpius s.str. is …

The Size Relationship Of 12 Days Post-Exodus Larvae With 56 Day Post-Exodus Fingerlings Regarding Growth And Survival In Bluegill (Lempomis Macrochirus), J.L. Schulte, James E. Wetzel

Cooperative Extension Research Publications

Low survival and quality of early life-stage bluegill is an obstacle to viable production where size may influence weaning efficiency. Herein, we investigate through two trials the effects of fry size 12-d post-exodus on total length, weight, production and survival through 56-d post-exodus. Full sibling broods (trial 1=10, trial 2=6) were reared with feedings of brine shrimp Artemia sp. nauplii (BS) through 12-d post-exodus (PE). Broods of trial 1 were visual sorted 12 d PE into small and large size groups. Fry (n = 25) from each size group were sampled for measured total length (TL) and weight. Starting 14 …