Digital Commons Network^™

Can The Cdc's Get Smart Program And A Decision Tree Alter Clinician Guideline Adherence For Abrs And Avrs?, Tracy R. Wilson

DNP Projects

In previous bodies of work, researchers have not evaluated clinicians’ treatment of AVRS and ABRS by examining the impact of a national education toolkit and a decision tree tool. It is the intent of this scholarly project to determine whether an educational program based on a national education toolkit plus a decision tree tool offered to health care providers in a Middle Tennessee walk-in clinic, promoted an increase in treatment guideline adherence when diagnosing and treating acute bacterial rhinosinusitis and acute viral rhinosinusitis.

Endemicity Of Chytridiomycosis Features Pathogen Overdispersion, Laura F. Grogan, Andrea D. Phillott, Benjamin C. Scheele, Lee Berger, Scott D. Cashins, Sara C. Bell, Robert Puschendorf, Lee F. Skerratt

School of Biological and Marine Sciences

No abstract provided.

Pilz Domain Protein Flgz Mediates Cyclic Di-Gmp-Dependent Swarming Motility Control In Pseudomonas Aeruginosa, Amy Baker, Andreas Diepold, Sherry Kuchma, Jessie Scott, Dae Gon Ha, Giulia Orazi, Judith Armitage, George A. O'Toole

Dartmouth Scholarship

The second messenger cyclic diguanylate (c-di-GMP) is an important regulator of motility in many bacterial species. In Pseudomonas aeruginosa, elevated levels of c-di-GMP promote biofilm formation and repress flagellum-driven swarming motility. The rotation of P. aeruginosa's polar flagellum is controlled by two distinct stator complexes, MotAB, which cannot support swarming motility, and MotCD, which promotes swarming motility. Here we show that when c-di-GMP levels are elevated, swarming motility is repressed by the PilZ domain-containing protein FlgZ and by Pel polysaccharide production. We demonstrate that FlgZ interacts specifically with the motility-promoting stator protein MotC in a c-di-GMP-dependent manner and that a …

Multi-Scale Modeling And Assessment Of Malaria Risk In Northern South America, Temitope O. Alimi

Open Access Dissertations

With malaria control in Latin America firmly established in most countries and a growing number of these countries in the pre-elimination phase, malaria elimination appears feasible. A review of the literature indicates that malaria elimination in this region will be difficult without locally tailored strategies for vector control, which depend on more research on vector ecology, genetics and behavioral responses to environmental changes, such as those caused by land cover alterations, and human population movements. An essential way to bridge the knowledge gap and improve vector control is through risk mapping. Malaria risk maps based on statistical and knowledge-based modelling …

Affecting Tdap Vaccination Rates Among Women: A Multifaceted Intervention, Soneka Wynter

Evidence-Based Practice Project Reports

Despite the availability of a preventive vaccine, the incidence of pertussis in the United States has continued to increase over the past two decades and it is now considered the most common preventable infectious illness. Highly contagious in nature, it is estimated that about 50 million people are infected each year, and approximately 300,000 deaths occur worldwide (Centers for Disease Control and Prevention [CDC], 2012). In 2013, Indiana reported 616 cases (Indiana State Department of Health [ISDH], 2014). In spite of CDC recommendations on strategies that can improve vaccine delivery, rates of immunization remain low nationwide (CDC, 2014). The purpose …

Current Therapeutic Role And Medicinal Potential Of Scutellaria Barbata In Traditional Chinese Medicine And Western Research, Geyang Tao, Marcy J. Balunas

Honors Scholar Theses

ETHNOPHARMACOLOGICAL RELEVANCE: Scutellaria barbata is a common herb in Traditional Chinese Medicine (TCM) most often used to treat cancer. S. barbata has been found to exhibit efficacy both in vitro and in vivo on a variety of cancer types. Similarly encouraging results have been shown in patients with metastatic breast cancer from Phase Ia and Ib clinical trials. This study aims to elucidate the current use of S. barbata by TCM practitioners and in current Western research.

MATERIALS AND METHODS: Semi-structured interviews were conducted with fifteen TCM practitioners in Beijing and Nanjing, China to understand their clinical use of …

Synbiotic Ice Cream As A Probiotic Carrier Tested In A Human Blind Crossover Trial, Erin M. Mcnamara

Department of Nutrition and Health Sciences: Dissertations, Theses, and Student Research

Diet is an important factor in gastrointestinal health. A synbiotic food option utilizing prebiotic and probiotic ingredients may be beneficial for improving gastrointestinal health. To conduct a human subject study of synbiotic ice cream containing prebiotic (inulin) and two strains of probiotics (Lactobacillus casei KE99 and Bifidobacterium bifidum) to determine its effectiveness as a carrier for a these ingredients and to identify any negative gastrointestinal side effects.

The study started with baseline data collection including a food frequency, a three day food recall, and one stool sample. The study was a 12 week crossover design with three weeks consuming …

Integrating Correctional And Community Health Care: An Innovative Approach For Clinical Learning In A Baccalaureate Nursing Program., Mary T. Bouchaud, Beth Ann Swan

College of Nursing Faculty Papers & Presentations

PROBLEM: With an evolving focus on primary, community-based, and patient-centered care rather than acute, hospital-centric, disease-focused care, and recognition of the importance of coordinating care and managing transitions across providers and settings of care, registered nurses need to be prepared from a different and broader knowledge base and skills set. A culture change among nurse educators and administrators and in nursing education is needed to prepare competent registered nurses capable of practicing from a health promotion, disease prevention, community- and population-focused construct in caring for a population of patients who are presenting health problems and conditions that persist across decades …

Geographic Distribution Of Maternal Group B Streptococcus Colonization And Infant Death During Birth Hospitalization: Eastern Wisconsin, Jessica J. F. Kram, Dennis J. Baumgardner, Kiley B. Vander Wyst, Melissa A. Lemke

Journal of Patient-Centered Research and Reviews

Purpose

Maternal group B Streptococcus (GBS) can be transmitted from a colonized mother to newborn during vaginal delivery and may or may not contribute to infant death. This study aimed to explore the geographic distribution and risk factors of maternal GBS colonization and infant death during birth hospitalization.

Methods

We retrospectively studied mothers with live birth(s) in a large eastern Wisconsin hospital system from 2007 through 2013. Associations between maternal and neonatal variables, GBS colonization and infant death were examined using chi-squared, Mann-Whitney U and t-tests. Multivariable logistic regression models also were developed.

Results

Study population (N = 99,305) had …

Clinical Approach To Nonresponsive Pneumonia In Adults Diagnosed By A Primary Care Clinician: A Retrospective Study, Kiley B. Vander Wyst, Jessica J. F. Kram, Dennis J. Baumgardner

Journal of Patient-Centered Research and Reviews

Purpose

Community-acquired pneumonia (CAP) is commonly diagnosed in the primary care setting. Management of nonresponsive pneumonia (NRP), i.e. failure to respond to CAP treatment, is not clearly understood. The purpose of this study was to describe the initial work-up and treatment of CAP in the ambulatory primary care setting and to determine relative proportion of, diagnostic approach to and treatment of NRP.

Methods

We retrospectively studied adult patients diagnosed with CAP within our large, integrated health care system from October 2006 through July 2013. Cases were defined as patients with CAP who worsened after 4 days, or did not improve …

Geodemographic Features Of Human Blastomycosis In Eastern Wisconsin, Megan E. Huber, Dennis J. Baumgardner, Jessica J. F. Kram, Melissa A. Lemke

Journal of Patient-Centered Research and Reviews

Purpose

Blastomycosis is an endemic fungal infection. In rural northern Wisconsin, blastomycosis cases are associated with certain environmental features including close proximity to waterways. Other studies have associated blastomycosis with particular soil chemicals. However, blastomycosis also occurs in urban and suburban regions. We explored the geodemographic associations of blastomycosis cases in the more urban/suburban landscape of eastern Wisconsin.

Methods

We conducted a retrospective study of 193 laboratory-identified blastomycosis cases in a single eastern Wisconsin health system, 2007–2015. Controls were 250 randomly selected cases of community-diagnosed pneumonia from a similar time period. Geographic features of home addresses were explored using Google …

Is 13-Valent Pneumococcal Conjugate Vaccine (Pcv13) Combined With 23-Valent Pneumococcal Polysaccharide Vaccine (Ppsv23) Superior To Ppsv23 Alone For Reducing Incidence Or Severity Of Pneumonia In Older Adults? A Clin-Iq, Starla Hayward, Lou Ann Thompson, Andrea Mceachern

Journal of Patient-Centered Research and Reviews

Pneumonia infection is a significant cause of morbidity and mortality worldwide. In addition to the public health concerns, pneumonia also accounts for a significant cost to the health care system. Currently there are two leading vaccines targeted against Streptococcus pneumoniae: 23-valent pneumococcal polysaccharide vaccine (PPSV23) and 13-valent pneumococcal conjugate vaccine (PCV13). Until recently, the recommendation for adult pneumonia vaccination has been a single dose of PPSV23 for all adults aged 65 years or older. However, concerns were raised regarding the vaccine’s efficacy due to the persistent burden of pneumococcal disease in the elderly population. This paper focuses on two …

Blastomyces: Why Be Dimorphic?, Dennis J. Baumgardner

Journal of Patient-Centered Research and Reviews

In introducing the infectious disease focus for this edition of the Journal of Patient-Centered Research and Reviews, the author describes the unsolved mysteries surrounding the dimorphic fungus Blastomyces and the related pathogenesis of pulmonary blastomycosis.

Epidemiology Crucial To Cracking Elizabethkingia Crisis, Angela Tonozzi

Journal of Patient-Centered Research and Reviews

The author explains the epidemiological methods, tools and personnel required to pinpoint the source of Wisconsin’s 2016 outbreak of Elizabethkingia infections.

Disease-Causing Fungi In Homes And Yards In The Midwestern United States, Dennis J. Baumgardner

Journal of Patient-Centered Research and Reviews

A number of fungal pathogens that may result in a variety of human diseases are found in residential homes and yards. The growth of these microscopic fungi is often favored by particular characteristics of the dwelling and nearby outdoor environment. Evolved virulence factors or increased ability of specific fungi to grow in diverse, and sometimes harsh, microenvironments presented by the domestic environment may promote growth and pathogenesis. Infection may occur by inhalation or direct inoculation and include endemic fungi in addition to opportunistic or emerging species. Systemic or locally aggressive fungal infections are particularly likely and may be life-threatening in …

A Study Of Insecticide Resistance In West Nile Virus Vectors: Culex Pipiens And Culex Quinquefasciatus In Shelby County, Tennessee, Cyril Patra

Electronic Theses and Dissertations Archive

West Nile Virus (WNV) is a vector-borne virus transmitted to humans through mosquitoes. Shelby County, Tennessee had 138 cases of WNV and 11 fatalities from 2002 to 2014. Genus Culex mosquitoes are an important vector for the disease. Since there is no treatment available, a WNV outbreak is a growing public health concern in Shelby County. The purpose of this study was to assess the efficacy of commonly used insecticides in Shelby County and evaluate the presence of resistance. Partial resistance was found for permethrin, deltamethrin, chlorpyrifos, and bendiocarb. Permethrin performed the poorest in comparison to deltamethrin, chlorpyrifos, and bendiocarb. …

The Firece Green Fire: Vol. 6 Issue 23, Wofford College Environmental Studies Program

The Fierce Green Fire

No abstract provided.

“One Health” Or Three? Publication Silos Among The One Health Disciplines, Kezia R. Manlove, Josephine G. Walker, Meggan E. Craft, Kathryn P. Huyvaert, Maxwell B. Joseph, Ryan S. Miller, Pauline Nol, Kelly A. Patyk, Daniel O'Brien, Daniel P. Walsh, Paul C. Cross

Wildland Resources Faculty Publications

The One Health initiative is a global effort fostering interdisciplinary collaborations to address challenges in human, animal, and environmental health. While One Health has received considerable press, its benefits remain unclear because its effects have not been quantitatively described. We systematically surveyed the published literature and used social network analysis to measure interdisciplinarity in One Health studies constructing dynamic pathogen transmission models. The number of publications fulfilling our search criteria increased by 14.6% per year, which is faster than growth rates for life sciences as a whole and for most biology subdisciplines. Surveyed publications clustered into three communities: one used …

Gradenigo Syndrome: A Rare Complication Of Otitis Media, Paul Brent Ferguson, Md

Marshall Journal of Medicine

Gradenigo syndrome is a very rare complication of otitis media that if left unrecognized and subsequently untreated will result in severe neurologic sequelae. Gradenigo Syndrome clinically represented by the triad of otitis media, ipsilateral, abducens nerve palsy and dysasthesia within the V1 and V2 divisions of the trigeminal nerve branches. We describe a 4 year-old patient who presented with headache, facial pain, diplopia and a recent history of upper respiratory tract symptomatology. Examination revealed an abducens palsy with subsequent magnetic resonance imaging demonstrating inflammation in the left petrous apex and along the tracts of the 6^th, 7^{th …}

The Humanitarian Narrative: Defining And Problematizing An Emerging Literary Genre, Jolena Zabel

International Studies Honors Projects

This thesis defines and problematizes the emerging Anglo-American literary genre of the humanitarian narrative. It interrogates its characteristics, origins, and significance. It first defines the genre, noting its primary conventions, which include an exceptional Hero, exotic setting, and an autobiographical or laudatory-biographical narrative approach. The thesis then argues that its emergence flows from converging Anglo-American literary and political histories and traditions that extol (Western) Heroes, human rights, and Western humanitarian intervention in the Global South. Three extended close readings follow, illuminating and critiquing the genre’s features: Little Princes by Conor Grennan (2014); Three Cups of Tea by Greg Mortenson and …

Untying The Knot: Child Marriage In Situations Of Armed Conflict, Jolena Zabel

Political Science Honors Projects

Child marriage is one of the largest global human rights concerns today; one in three girls worldwide under age eighteen are married, negatively impacting their health, economic wellbeing, and education. While studies have been done on child marriage outside of conflict and, separately, on gender-based violence in armed conflict, little is known about what happens to child marriage in situations of armed conflict. This paper argues that child marriage in situations of armed conflict has both cultural and economic drivers, as is the case outside of conflict. Using the case of Syria, it shows that the effects of conflict, including …

Silent Resistance: The History And Resonance Of 19th Century Photographs Of Native Americans, Maria Carmela Ferguson

Electronic Theses and Dissertations Archive

Although nineteenth-century photographs of Native Americans were often created to portray romanticized images of a "vanishing race," they can also represent the agency of those pictured. In this paper, Ipresent research on a collection of photographs taken of Osage Indians by George W. Parsons in Pawhuska, Indian Territory, during the late nineteenth-century. In order to support my claim that the photographs in the collection are examples of silent resistance practiced by Native Americans, Idiscuss the history of representation of Native Americans and highlight elements of Osage culture illustrated by the photographs. In doing so, I demonstrate how the images illustrate …

Novel Agents And Comparative Efficacy In The Prevention And Management Of Post-Herpetic Neuralgia, Laurie A. Chittum

Nursing Capstones

No abstract provided.

Improving The State Of Health Literacy Among American Adults: Why Community Outreach Methods Are More Effective Than Literacy-Level Screenings, Lydia Simpson

Honors Theses

Health literacy refers to an individual’s ability to access and process health information to make important decisions about their health. Unfortunately, millions of American adults have inadequate health literacy skills and are not able to navigate their way through the world of health care. This may lead to disastrous consequences and poor health outcomes. To improve health literacy, nationwide health education programs are imperative. Despite this, low health literacy is often ignored, or only considered for individuals suspected of having low health literacy who might then be administered a screening instrument. A better model for the American health care system …

Renewing Curiosities, Marveling At The Wonders Of Biology, And Promoting Deep Approaches To Learning With Non-Science Majors, Carol A. Hurney, Sofia Ganev, Alexandra Higgins

Teaching and Learning Together in Higher Education

No abstract provided.

The Effects Of The Fungus Beauvaria Sp. On The Cave Cricket, Hadenoecus Subterraneus, Christina N. Walker, Derrick J. Jent, Claire A. Fuller

Scholars Week

The cave cricket, Hadenoecus subterraneus, is a keystone species in cave ecosystems within Mammoth Cave National Park (MCNP). Within MCNP, many cricket cadavers have been found

with a thick, white fungus growing on them; this fungus has previously been identified to be Beauveria bassiana. However, new molecular data suggests that this may actually be the species B. amorpha. Cricket cadavers with Beauveria sp. were collected from MCNP and cultured on potato dextrose agar. Cultures will be sent to the USDA for a genetic analysis and identification of the fungus. The purpose of this study is to examine if the relationship …

Extension For Community Health Outcomes-Hepatitis C: Small Steps Carve Big Footprints In The Allocation Of Scarce Resources For Hepatitis C Virus Treatment To Remote Developing Areas, Veysel Tahan, Ashraf Almashhrawi, Ali M. Kahveci, Rachel Mutrux, Jamal A. Ibdah

Project ECHO Bibliography

Hepatitis C virus (HCV) infection is still a major health problem throughout the world. HCV patients living in rural areas are less fortunate than their counterparts residing in populous urbanized regions. The lack of medical resources and properly trained medical personnel in rural regions make it especially burdensome for HCV patients seeking treatment. Dr. Sanjeev Arora at the University of New Mexico Health Sciences Center took initiative to resolve the issue at hand by developing a model named Project Extension for Community Health Outcomes (ECHO). ECHO connects primary care providers (PCPs), usually family medicine physicians, in local communities with specialists. …

A Tale Of Two Theories: Using An Engineered Strain Of E. Coli To Bridge The Gap Between Quorum Sensing And Diffusion Sensing, Cortney E. Wilson

HCNSO Student Theses and Dissertations

Cooperation is a trait that is found at all levels of biological organization. Interestingly, cooperation appears to occur in bacteria that produce small, easily diffusible molecules called autoinducers. To understand why bacteria produce these autoinducers, the scientific community has focused on one predominant theory called quorum sensing. Under this theory, bacteria produce autoinducers so they can sense the density of the population. Once a sufficiently high population density is reached, autoinducers initiate the production of a costly gene product that serves to benefit the population. In contrast, a competing theory called diffusion sensing suggests that autoinducers are used by the …

Four From Uab Named To Association Of American Physicians, Staff

Browse All News

No abstract provided.

Week Of April 18, 2016, New York Medical College

InTouch

• "Innovation and Inspiration" Fuels Successful NYMedTalks
• SHSP Inducts New Members into Delta Omega and Alpha Eta Honor Societies
• SHSP Hosts Movie Screening to Mark National Public Health Week
• Resident Research Day Recognizes Scholarly Efforts of Residents
• Doc's Café Offers New Mini-Mart