Digital Commons Network^™

Kenyon Collegian - October 22, 2015

The Kenyon Collegian

No abstract provided.

Improving Healthspan Via Changes In Gut Microbiota And Fermentation, Michael J. Keenan, Maria L. Marco, Donald K. Ingram, Roy J. Martin

Faculty Publications

Dietary resistant starch impact on intestinal microbiome and improving healthspan is the topic of this review. In the elderly population, dietary fiber intake is lower than recommended. Dietary resistant starch as a source of fiber produces a profound change in gut microbiota and fermentation in animal models of aging. Dietary resistant starch has the potential for improving healthspan in the elderly through multiple mechanisms as follows: (1) enhancing gut microbiota profile and production of short-chain fatty acids, (2) improving gut barrier function, (3) increasing gut peptides that are important in glucose homeostasis and lipid metabolism, and (4) mimicking many of …

Migration In The Social Stage Of Dictyostelium Discoideum Amoebae Impacts Competition, Chandra N. Jack, Neil J. Buttery, Boahemaa Adu-Oppong, Michael Powers, Christopher R.L. Thompson, David Queller, Joan E. Strassmann

Biology Faculty Research

Interaction conditions can change the balance of cooperation and conflict in multicellular groups. After aggregating together, cells of the social amoeba Dictyostelium discoideum may migrate as a group (known as a slug) to a new location. We consider this migration stage as an arena for social competition and conflict because the cells in the slug may not be from a genetically homogeneous population. In this study, we examined the interplay of two seemingly diametric actions, the solitary action of kin recognition and the collective action of slug migration in D. discoideum, to more fully understand the effects of social competition …

Bayle's 'Rorarius,' Leibniz, And Animal Souls, Richard Fry

SIUE Faculty Research, Scholarship, and Creative Activity

Bayle produces a set of three criteria to evaluate views of non-human animal souls. These criteria arise from Bayle’s interaction with the extant Modern views on the topic and are meant to capture features that any successful view will have. Bayle criticizes Leibniz’s view of animal souls at length for its reliance on the theory of pre-established harmony, entering into a long exchange with Leibniz on the topic, but Bayle never explicitly applies his criteria. This leads some (including Leibniz) to conclude that Bayle thinks Leibniz’s view satisfies the criteria. I argue in this paper that Leibniz’s view properly satisfies …

The Scarlet - Volume Xcv, No. 5 (October 22, 2015), Scarlet Staff

The Scarlet (Student Newspaper) (2011-present)

The October 22, 2015 edition of The Scarlet (est. 1939), Clark University's student-run newspaper. The Scarlet is intellectually and editorially independent of the University.

Andrews Autumn Conference On Religion And Science: Keynote Speaker Gregory Boyd Presents Oct. 23-24, Becky St. Clair

Andrews Agenda: Campus News

The annual Andrews Autumn Conference on Religion and Science was scheduled for October 23-24, 2015. This article also provides a short background on the conference.

The Observer, Central Washington University

Student Newspaper

Student newspaper for Central Washington University for October 22-28, 2015. Vol. 101, No. 4.

The George-Anne, Georgia Southern University

The George-Anne

• Opinions
• News
• Features
• Sports
• Puzzles

The Montclarion, October 22, 2015, The Montclarion

The Montclarion

Student Newspaper of Montclair State University

The Vulnerability Of Indo-Pacific Mangrove Forests To Sea-Level Rise, Catherine E. Lovelock, Donald R. Cahoon, Daniel A. Friess, Glenn R. Guntenspergen, Ken W. Krauss, Ruth Reef, Kerrylee Rogers, Megan L. Saunders, Frida Sidik, Andrew Swales, Neil Saintilan, Le Xuan Thuyen, Tran Triet

United States Geological Survey: Staff Publications

Sea-level rise can threaten the long-term sustainability of coastal communities and valuable ecosystems such as coral reefs, salt marshes and mangroves^1,2. Mangrove forests have the capacity to keep pace with sea-level rise and to avoid inundation through vertical accretion of sediments, which allows them to maintain wetland soil elevations suitable for plant growth³. The Indo- Pacific region holds most of the world’s mangrove forests⁴, but sediment delivery in this region is declining, owing to anthropogenic activities such as damming of rivers⁵. This decline is of particular concern because the Indo-Pacific region is …

Unh Agriculture, Life Sciences Researchers Honored For Innovations, Lori Tyler Gula

UNH Today Archive

No abstract provided.

The Fungal Exopolysaccharide Galactosaminogalactan Mediates Virulence By Enhancing Resistance To Neutrophil Extracellular Traps, Mark J. Lee, Hong Liu, Bridget M. Barker, Brendan D. Snarr, Fabrice M. Gravelat, Qusai Al Abdallah, Christina Gavino, Shane R. Baistrocchi, Hanna Ostapska, Tianli Xiao, Benjamin Ralph, Norma V. Solis, Melanie Lehoux, Stefanie D. Baptista, Arsa Thammahong

Dartmouth Scholarship

Of the over 250 Aspergillus species, Aspergillus fumigatus accounts for up to 80% of invasive human infections. A. fumigatus produces galactosaminogalactan (GAG), an exopolysaccharide composed of galactose and N-acetyl-galactosamine (GalNAc) that mediates adherence and is required for full virulence. Less pathogenic Aspergillus species were found to produce GAG with a lower GalNAc content than A. fumigatus and expressed minimal amounts of cell wall-bound GAG. Increasing the GalNAc content of GAG of the minimally pathogenic A. nidulans, either through overexpression of the A. nidulans epimerase UgeB or by heterologous expression of the A. fumigatus epimerase …

The Rna World: 4,000,000,050 Years Old, Niles Lehman

Chemistry Faculty Publications and Presentations

The notion that molecular systems such as RNA can display a wide range of evolutionary processes in the absence of fully formed cellular life continues to gain support. Understanding how RNA can behave in an abiotic context is a key piece of our picture of how life developed and expanded on the Earth, and by proxy, elsewhere. We can study how RNA behaves in this regard through a combination of in vivo work (with small regulatory RNAs and larger catalytic RNAs alike), experimental work in the laboratory, and through powerful analytical and simulation studies. These efforts will not only grant …

"Thomas Mann, ‘Expressionism,’ And Ðeath In Venice” For “Death In Venice: Warrington Colescott And Thomas Mann”, David B. Dennis

History: Faculty Publications and Other Works

This was a public lecture in association with an excellent exhibition of works by one of America’s premier printmakers, on the theme of Mann’s work and German culture.

The Inkwell, Armstrong State University

The Inkwell

No abstract provided.

Intracellular Information Processing Through Encoding And Decoding Of Dynamic Signaling Features., Hirenkumar K Makadia, James S. Schwaber, Rajanikanth Vadigepalli

Department of Pathology, Anatomy, and Cell Biology Faculty Papers

Cell signaling dynamics and transcriptional regulatory activities are variable within specific cell types responding to an identical stimulus. In addition to studying the network interactions, there is much interest in utilizing single cell scale data to elucidate the non-random aspects of the variability involved in cellular decision making. Previous studies have considered the information transfer between the signaling and transcriptional domains based on an instantaneous relationship between the molecular activities. These studies predict a limited binary on/off encoding mechanism which underestimates the complexity of biological information processing, and hence the utility of single cell resolution data. Here we pursue a …

The Transcriptional Landscape Of Age In Human Peripheral Blood, Marjolein J. Peters, Roby Joehanes, Luke C. Pilling, Claudia Schurmann, Karen N. Conneely, Harald H. H. Goring, Joanne E. Curran, Sarah Williams-Blangero, John Blangero

School of Medicine Publications

Disease incidences increase with age, but the molecular characteristics of ageing that lead to increased disease susceptibility remain inadequately understood. Here we perform a whole-blood gene expression meta-analysis in 14,983 individuals of European ancestry (including replication) and identify 1,497 genes that are differentially expressed with chronological age. The age-associated genes do not harbor more age-associated CpG-methylation sites than other genes, but are instead enriched for the presence of potentially functional CpG-methylation sites in enhancer and insulator regions that associate with both chronological age and gene expression levels. We further used the gene expression profiles to calculate the 'transcriptomic age' of …

We Are...Marshall, October 21, 2015, Office Of Marshall University Communications

We Are ... Marshall: the Newsletter for Marshall University 1999-2023

No abstract provided.

Stability, Structure, And Reactivity Of Biotemplated Metal Nanoparticles, Nicholas A. Merrill

Open Access Dissertations

Metal nanomaterials are used for a variety of applications ranging from biomedical to electronics. Gold nanomaterials are of particular interest due to their unique optical and electronic properties and the ability to easily functionalize the gold surface. One disadvantage to using gold nanorods in biological applications is the lack of particle stability during surface modification processes. In this regard, the surfactant concentration during gold nanorod washing was studied for multiple washing steps where a minimum CTAB concentration of 0.5 mM was required to maintain stability throughout 10 wash cycles. While there are numerous routes to synthesize metal nanomaterials, biomolecules such …

10-21-2015 Health Careers Day Planned November 12 At Swosu, Southwestern Oklahoma State University

THE BARK ARCHIVE 2015

Registration is underway for an upcoming Health Careers Day to be held at Southwestern Oklahoma State University on Thursday, November 12.

The Dueling Influences On Stigma Toward Mental Illness: Effects Of Interpersonal Familiarity And Stigmatizing Mediated Portrayals Of Mental Illness On Attitudes, Bridget Rubenking, Cheryl C. Bracken

Communication Faculty Publications

Popular media is both a common source for information about mental illness and notorious for its disproportionately negative and violent portrayals of those with mental illness. This research undertook an experiment (N = 92) to explore the competing influences of mass communication messages and interpersonal familiarity/ experience with people with mental illness on stigmatizing attitudes toward the mentally ill. Results demonstrate that exposure to negative, violent mediated portrayals of the mentally ill increase stigmatizing attitudes toward the mentally ill, while exposure to positive, sympathetic portrayals of the mentally ill relates to less stigmatizing attitudes toward the mentally ill. Greater interpersonal …

Outstanding Educational Performance Awards: Highlighting High-Achieving Arkansas Schools, 2015, Charlene A. Reid, Gary W. Ritter

Arkansas Education Reports

In this report, we are presenting a list of the top 25 schools in each area. In some cases, these “top 25 lists” will contain more than 25 schools as some schools’ GPA scores will be identical. This is not a new phenomenon, as we also exceeded 25 schools in previous reports when using the percent proficient and advanced metric as an indicator for student achievement; however, there are fewer ties using the more precise GPA measure.

Science exams were only administered in grades 5, 7, and to students completing Biology. There are very different performance patterns by grade: Fifth …

Successfully Employing Single-Use Bioreactors For Different Expression Systems, Valentin Jossen, Regine Eibl, Dieter Eibl

Single-Use Technologies: Bridging Polymer Science to Biotechnology Applications

The single-use bioreactor market was estimated to have grown at a CAGR of 20% in 2014. Wave-mixed bioreactors and stirred bioreactors represent the largest segment of today`s single-use bioreactor market, and are preferred by process developers and manufacturers of preclinical and clinical samples when high-value products up to medium scale and products requiring high safety demands are in focus. However, wave-mixed and stirred single-use bioreactors are also becoming increasingly important for commercial biopharmaceutical productions. This is ascribed to the availability of high-productivity cell lines, which require smaller bioreactors. In addition, the availability of bioengineering data and cultivation bags with improved …

The Lumberjack, October 21, 2015, The Lumberjack Staff

2015

The student newspaper of Humboldt State University

Applying Practices From The Medical Device Industry To Ensure Patient Safety Of Single-Use Products In The Biotechnology Industry, Jan Oberdoerster

Single-Use Technologies: Bridging Polymer Science to Biotechnology Applications

Biocompatibility (i.e., the quality of not having toxic or injurious effects on biological systems) requirements for single-use products in the biotechnology industry can vary depending on point of use. For example, single-use syringes are considered a combination medical device and thus require assessment according to the ISO 10993 standards with test ranging from acute systemic toxicity to genotoxicity to sensitization. Processing equipment (e.g., reaction vessels, tubing, filters, chromatography columns) in contrast, generally requires a USP Class VI designation (a battery of in vivo tests consisting of acute systemic toxicity, intracutaneous reactivity, and muscle implantation) with rigorous requirements for leachates. The …

Homogenizing Biologic Drug Substance Bulk Using Single Use Mixing Systems, Benson Gikanga, Yufei Chen, Oliver Stauch, Yuh-Fun Maa

Single-Use Technologies: Bridging Polymer Science to Biotechnology Applications

Mixing of biologic Drug Substance (DS) is a critical process step during manufacturing of biologic Drug Product (DP). Generally, mixers used are equipped with either bottom-mounted or top-mounted agitators. Bottom-mounted mixers (BMMs), particularly those that are magnetically driven, are preferred because of their associated low risk of contamination, ease of use, and ability to accommodate low minimum mixing volumes. Despite these benefits the mechanical coupling of the rotating impeller and the male bearing on the tank may lead to shearing of monoclonal antibody (mAb) formulations generating elevated amount of particles in the DS or DP solution. This may lead to …

Complete Mitochondrial Genome Of The Speckled Dace Rhinichthys Osculus, A Widely Distributed Cyprinid Minnow Of Western North America, Samantha J. Bock, Morgan M. Malley, Sean Lema

Biological Sciences

The speckled dace Rhinichthys osculus (order Cypriniformes), also known as the carpita pinta, is a small cyprinid minnow native to western North America. Here, we report the sequencing of the full mitochondrial genome (mitogenome) of R. osculus from a male fish collected from the Amargosa River Canyon in eastern California, USA. The assembled mitogenome is 16 658 base pair (bp) nucleotides, and encodes 13 protein-coding genes, and includes both a 12S and a 16S rRNA, 22 tRNAs, and a 985 bp D-loop control region. Mitogenome synteny reflects that of other Ostariophysian fishes with the majority of genes and RNAs encoded …

Female Sex Hormone May Save Injured Soldiers On The Battlefield, Jeff Hansen

Browse All News

No abstract provided.

Abq Free Press, October 21, 2015, Abq Free Press

ABQ Free Press

No abstract provided.

Volume 53, Number 10: October 21, 2015, University Of North Dakota

University Letter Archive

No abstract provided.