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2015

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Sex Differences In The Kinetic Profiles Of D- And L- Methylphenidate In The Brains Of Adult Rats, J. Bentley, F. Snyder, Stacy D. Brown, R. W. Brown, Brooks B. Pond Jan 2015

Sex Differences In The Kinetic Profiles Of D- And L- Methylphenidate In The Brains Of Adult Rats, J. Bentley, F. Snyder, Stacy D. Brown, R. W. Brown, Brooks B. Pond

ETSU Faculty Works

OBJECTIVE: Methylphenidate is commonly used in the treatment of Attention Deficit Hyperactivity Disorder and narcolepsy. Methylphenidate is administered as a racemic mixture of the d- and l- threo enantiomers; however, the d-enantiomer is primarily responsible for the pharmacologic activity. Previous studies of the behavioral effects of methylphenidate have highlighted sex differences in the responsiveness to the drug, namely an increased sensitivity of females to its stimulatory effects. These differences may be due to differences in the uptake, distribution, and elimination of methylphenidate from male and female brains. Therefore, we compared the pharmacokinetics of d- and l- threo methylphenidate in the …


2014-2015 Tennessee Higher Education Fact Book, Tennessee Higher Education Commission Jan 2015

2014-2015 Tennessee Higher Education Fact Book, Tennessee Higher Education Commission

Higher Education Fact Book

No abstract provided.


Evaluating The Vegetation Recovery In The Damage Area Of Wenchuan Earthquake Using Modis Data, Wei-Guo Jiang, Kai Jia, Jian-Jun Wu, Zhenghong Tang, Wen-Jie Wang, Xiao-Fu Liu Jan 2015

Evaluating The Vegetation Recovery In The Damage Area Of Wenchuan Earthquake Using Modis Data, Wei-Guo Jiang, Kai Jia, Jian-Jun Wu, Zhenghong Tang, Wen-Jie Wang, Xiao-Fu Liu

Community and Regional Planning Program: Faculty Scholarly and Creative Activity

The catastrophic 8.0 Richter magnitude earthquake that occurred on 12 May 2008 in Wenchuan, China caused extensive damage to vegetation due to widespread landslides and debris flows. In the past five years, the Chinese government has implemented a series of measures to restore the vegetation in the severely afflicted area. How is the vegetation recovering? It is necessary and important to evaluate the vegetation recovery effect in earthquake-stricken areas. Based on MODIS NDVI data from 2005 to 2013, the vegetation damage area was extracted by the quantified threshold detection method. The vegetation recovery rate after five years following the earthquake …


Mitotic Recombination In Saccharomyces Cerevisiae Results From Genetic Instability At Fragile Site Fs2, Shaylynn Delaney Miller Jan 2015

Mitotic Recombination In Saccharomyces Cerevisiae Results From Genetic Instability At Fragile Site Fs2, Shaylynn Delaney Miller

Senior Honors Theses and Projects

Common fragile sites (CFSs) are present in a number of species and are considered a normal structural feature of the eukaryotic chromosome. CFSs are regions of genetic instability prone to breaking under DNA replication stress. Cancer is a possible result of DNA breaks that lead to a loss of heterozygosity (LOR) in the cell. Mitotic homologous recombination is a method of DNA repair following a break from DNA instability. Our experiments investigated the role of mitotic recombination in the development of LOH. Replication stress was induced in Saccharomyces cerevisiae through the use of the GALl/lO promoter; this modified promoter …


Does The Structure Of The United States Child Welfare System Possess The Ability To Adequately Treat Mental Health Concerns For Foster Care Youth?, Vanisha Sophya Dejonghe Jan 2015

Does The Structure Of The United States Child Welfare System Possess The Ability To Adequately Treat Mental Health Concerns For Foster Care Youth?, Vanisha Sophya Dejonghe

Senior Honors Theses and Projects

No abstract provided.


Musculoskeletal Markers Of Linguistic Variance On The Human Mandible, Hannah Catherine Hilbert Jan 2015

Musculoskeletal Markers Of Linguistic Variance On The Human Mandible, Hannah Catherine Hilbert

Senior Honors Theses and Projects

Skeletal morphology is greatly influenced by muscle action and articulation. Exertion of force by muscle use permanently alters bone shape. It can therefore be assumed that the muscles involved in speech production would play a role in shaping the stomatognathic structures (i.e. relating to the mouth and jaw). This study has been designed to explore the resulting cranio-facial manifestations of linguistic diversity amongst modern Homo sapiens. Utilizing data independently collected from American, French, and Philippine skeletal collections, it is concluded that a correlation exists (albeit not significant) between observed musculoskeletal markers on the human mandible and the repetitive tongue …


The Effects Of Salinity On The Stratification And Nutrient Dynamics Of Inland Lakes In Southeast Michigan, Hallee Kansman Jan 2015

The Effects Of Salinity On The Stratification And Nutrient Dynamics Of Inland Lakes In Southeast Michigan, Hallee Kansman

Senior Honors Theses and Projects

Temperate lakes typically turnover twice annually; however, certain factors can reduce the possibility of turnover. One of these factors may be the addition of road salt to the watershed. Road salt increases the density of water, increasing the energy needed to turnover a lake. Reduced turnover can have major effects on the nutrient dynamics of the lake. In this study, I examined seven small, deep lakes in Southeast Michigan to determine if turnover was affected by salinity. The purpose of this study was to determine whether these turnover events in TSL have changed since 2009 and how common incomplete spring …


Candida Albicans Quorum Sensing Molecules Stimulate Mouse Macrophage Migration, Jessica C. Hargarten, Tyler C. Moore, Thomas M. Petro, Kenneth W. Nickerson, Audrey L. Atkin Jan 2015

Candida Albicans Quorum Sensing Molecules Stimulate Mouse Macrophage Migration, Jessica C. Hargarten, Tyler C. Moore, Thomas M. Petro, Kenneth W. Nickerson, Audrey L. Atkin

Kenneth Nickerson Papers

The polymorphic commensal fungus Candida albicans causes life-threatening disease via bloodstream and intra-abdominal infections in immunocompromised and transplant patients. Although host immune evasion is a common strategy used by successful human fungal pathogens, C. albicans provokes recognition by host immune cells less capable of destroying it. To accomplish this, C. albicans white cells secrete a low-molecular-weight chemoattractive stimulant(s) of macrophages, a phagocyte that they are able to survive within and eventually escape from. C. albicans opaque cells do not secrete this chemoattractive stimulant( s). We report here a physiological mechanism that contributes to the differences in the interaction of C. …


Winter Commencement, December 19, 2015, Eastern Michigan University Jan 2015

Winter Commencement, December 19, 2015, Eastern Michigan University

Commencement Programs and Materials

No abstract provided.


Emu Today, January 9, 2015, Eastern Michigan University Jan 2015

Emu Today, January 9, 2015, Eastern Michigan University

EMU Today

No abstract provided.


Emu Today, January 8, 2015, Eastern Michigan University Jan 2015

Emu Today, January 8, 2015, Eastern Michigan University

EMU Today

No abstract provided.


Emu Today, January 16, 2015, Eastern Michigan University Jan 2015

Emu Today, January 16, 2015, Eastern Michigan University

EMU Today

No abstract provided.


Emu Today, January 12, 2015, Eastern Michigan University Jan 2015

Emu Today, January 12, 2015, Eastern Michigan University

EMU Today

No abstract provided.


Emu Today, January 26, 2015, Eastern Michigan University Jan 2015

Emu Today, January 26, 2015, Eastern Michigan University

EMU Today

No abstract provided.


Emu Today, January 23, 2015, Eastern Michigan University Jan 2015

Emu Today, January 23, 2015, Eastern Michigan University

EMU Today

No abstract provided.


Emu Today, January 21, 2015, Eastern Michigan University Jan 2015

Emu Today, January 21, 2015, Eastern Michigan University

EMU Today

No abstract provided.


Emu Today, January 20, 2015, Eastern Michigan University Jan 2015

Emu Today, January 20, 2015, Eastern Michigan University

EMU Today

No abstract provided.


Emu Today, January 19, 2015, Eastern Michigan University Jan 2015

Emu Today, January 19, 2015, Eastern Michigan University

EMU Today

No abstract provided.


Emu Today, January 30, 2015, Eastern Michigan University Jan 2015

Emu Today, January 30, 2015, Eastern Michigan University

EMU Today

No abstract provided.


Emu Today, January 29, 2015, Eastern Michigan University Jan 2015

Emu Today, January 29, 2015, Eastern Michigan University

EMU Today

No abstract provided.


Emu Today, January 28, 2015, Eastern Michigan University Jan 2015

Emu Today, January 28, 2015, Eastern Michigan University

EMU Today

No abstract provided.


Emu Today, February 4, 2015, Eastern Michigan University Jan 2015

Emu Today, February 4, 2015, Eastern Michigan University

EMU Today

No abstract provided.


Emu Today, February 3, 2015, Eastern Michigan University Jan 2015

Emu Today, February 3, 2015, Eastern Michigan University

EMU Today

No abstract provided.


Emu Today, February 11, 2015, Eastern Michigan University Jan 2015

Emu Today, February 11, 2015, Eastern Michigan University

EMU Today

No abstract provided.


Emu Today, February 10, 2015, Eastern Michigan University Jan 2015

Emu Today, February 10, 2015, Eastern Michigan University

EMU Today

No abstract provided.


Emu Today, March 3, 2015, Eastern Michigan University Jan 2015

Emu Today, March 3, 2015, Eastern Michigan University

EMU Today

No abstract provided.


Emu Today, April 10, 2015, Eastern Michigan University Jan 2015

Emu Today, April 10, 2015, Eastern Michigan University

EMU Today

No abstract provided.


Emu Today, April 9, 2015, Eastern Michigan University Jan 2015

Emu Today, April 9, 2015, Eastern Michigan University

EMU Today

No abstract provided.


Emu Today, April 7, 2015, Eastern Michigan University Jan 2015

Emu Today, April 7, 2015, Eastern Michigan University

EMU Today

No abstract provided.


Emu Today, April 16, 2015, Eastern Michigan University Jan 2015

Emu Today, April 16, 2015, Eastern Michigan University

EMU Today

No abstract provided.