Digital Commons Network^™

Individual Strength-Based Assessment For Adult Empowerment Ngos, Ashley T. Turner

MA IDS Thesis Projects

The purpose of this culminating comprehensive project is to advise adult empowerment focused NGOs on the importance of identifying and leveraging the strengths of the individuals they serve. Given the evidence that all individuals innately have strengths, it is important to be aware of them in order to properly engage such assets. Character strengths are studied in this paper as one of the main pillars in the field of positive psychology. This culminating comprehensive project reviews the literature on positive psychology to best understand how empowerment can be achieved. Accompanying this research is a sample resource guide that was designed …

A Nuclear Fraction Of Turnip Crinkle Virus Capsid Protein Is Important For Elicitation Of The Host Resistance Response, Sung-Hwan Kang, Feng Qu, Thomas J. Morris

Nebraska Center for Virology: Faculty Publications

The N-terminal 25 amino acids (AAs) of turnip crinkle virus (TCV) capsid protein (CP) are recognized by the resistance protein HRT to trigger a hypersensitive response (HR) and systemic resistance to TCV infection. This same region of TCV CP also contains a motif that interacts with the transcription factor TIP, as well as a nuclear localization signal (NLS). However, it is not yet known whether nuclear localization of TCV CP is needed for the induction of HRT-mediated HR and resistance. Here we present new evidence suggesting a tight correlation between nuclear inclusions formed by CP and the manifestation of HR. …

A Novel Codon-Optimized Siv Gag-Pol Immunogen For Genebased Vaccination, Catherine M. Crosby, Eric A. Weaver, Reeti Khare, Michael A. Barry

Nebraska Center for Virology: Faculty Publications

Simian immunodeficiency virus (SIV) is a robust pathogen used in non-human primates to model HIV vaccines. SIV encodes a number of potential vaccine targets. By far the largest and most conserved protein target in SIV is its gag-pol protein that bears many epitopes to drive multivalent immune T cell responses. While gag-pol is an attractive antigen, it is only translated after a frame shift between gag and pol with the effect that gag and pol are expressed at an approximate 10/1 ratio. The codon bias of native lentiviral genes are also mismatched with the abundance of tRNAs in mammalian cells …

Ballast Water Regulation In The Great Lakes, Erin James

War Crimes Memoranda

No abstract provided.

Factors That Impact End-Of-Course Assessments In Indiana Public, Non-Charter High Schools, Donald Edward Harman

All-Inclusive List of Electronic Theses and Dissertations

The purpose of this study was to determine whether a relationship exists between Indiana End-of-Course Assessments (ECA) in English 10 and Algebra I and the following indicators at the high school level: (a) socioeconomic status, (b) instructional expenditures per student, (c) attendance rate, (d) school size, (e) percentage of ELLs, (f) mobility rate, (g) minority rate, and (h) percentage of specialEducation students. This study examined which indicators had the greatest effect on English 10 ECA scores and Algebra I ECA scores in Indiana. To expand the purpose of this study to a specific variable, the study also examined if there …

What About Protection? A Content Analysis Of Reducing The Risk, An Evidence-Based Sex Education Curriculum, Julia Desangles

Theses & ETDs

In this thesis, I analyze Reducing the Risk: Building the Skills to Prevent Pregnancy, STD & HIV (RTR). As one of the first evidence-based curricula in the U.S., RTR is now one of the numerous programs funded by the U.S. government. While this curriculum has been evaluated twice for its ability to influence student sexual behavior, messages found in the inclusion of abstinence and protection has not. Using an open coding method, I delve into this curriculum and find a disconnect between the stated goal of RTR—to provide students with the skills to abstain and use protection—and the material presented. …

“I Am Filled With Freedom”: A Staged Production And Translation Of Antigona...¡Cerda! By Luis Riaza, Sara Linares

Theses & ETDs

This thesis explores adaptation through translation in Luis Riaza’s dramatic text, Antígona...¡Cerda!. I have translated this play from Spanish to English and staged it at New College of Florida. The first chapter describes the sociohistorical and cultural context in which Riaza wrote the play as well as an explanation and analysis of his style of work. My translation of the play is the second chapter, which includes notes on directorial and translation choices. The final chapter is a reflection on the performance and the rehearsal process including an explanation on specific actor technique. A copy of the performance is attached …

Which Aspects Matter? The Effect Of Mentoring Satisfaction On Work Engagement For Female Accounting Faculty Members, Donna Whitten

All-Inclusive List of Electronic Theses and Dissertations

Although women have comprised the majority of accounting graduates in the United States since the mid 1980s, they are underrepresented in the accounting professoriate. Therefore, studies that add to an understanding of the factors that contribute to retaining those in the profession are valuable. Studies have been conducted to understand ways to support female faculty members, with mentoring in particular being one of those factors. However, there is a lack of scholarly work on mentoring female accounting faculty members and an absence of any research that seeks to empirically link aspects of mentoring with work engagement. Hence, the purpose of …

Social Behaviors Of Indiana Bats (Myotis Sodalis) At Day Roost Sites, Caroline M. Byrne

All-Inclusive List of Electronic Theses and Dissertations

Bats are highly social, but the study of bat social behavior was limited until recently due to technological limitations. Most of bat behavior is imperceptible to our senses, including both their use of ultrasound and their nocturnal activities. During the maternity seasons (May-August) of 2013 and 2014 near Plainfield, Indiana, we recorded Indiana bat (Myotis sodalis) roost site behaviors with emergence count observation, video (Sony Nightshot HandyCams and IR lights), and acoustic detectors (Pettersson D500X ultrasonic detectors). The objective of this study was to compile a catalog of observable and acoustic behaviors seen at M. sodalis day roost sites. We …

Research Agenda Into Human-Intelligence/Machine-Intelligence Governance, Teddy Steven Cotter

Engineering Management & Systems Engineering Faculty Publications

Since the birth of modern artificial intelligence (AI) at the 1956 Dartmouth Conference, the AI community has pursued modeling and coding of human intelligence into AI reasoning processes (HI Þ MI). The Dartmouth Conference's fundamental assertion was that every aspect of human learning and intelligence could be so precisely described that it could be simulated in AI. With the exception of knowledge specific areas (such as IBM's Big Blue and a few others), sixty years later the AI community is not close to coding global human intelligence into AI. In parallel, the knowledge management (KM) community has pursued understanding of …

Application Of Lipid Styryl Dye For Staining Intracytoplasmic Membranes In Gram-Negative Bacteria, Theodore J. Hammer

Williams Honors College, Honors Research Projects

Intracytoplasmic membranes are structures that form within cells which help facilitate a variety of different metabolic processes. This feature of intracellular membranes makes them particularly valuable for studying compartmentalization and cell dynamics in bacteria. In the past, transmission electron microscopy has been the primary method for imaging bacteria with intracytoplasmic membranes. Because transmission electron microscopy takes images of a cell in fixed slices, it’s impossible to follow a cell’s growth and development over time. Fluorescence microscopy is a particularly effective method of measurement that can combat these issues when evaluating live bacterial cells. Here, standard biochemical laboratory procedures were used …

Myriad Lessons Learned, Amelia Rinehart

Utah Law Faculty Scholarship

Maybe the most important lesson that can be learned from cases like Myriad (ones in which the legal problems are complex) is a subtle one: the big picture is complicated. After all, if every case were easy to resolve on the merits, all lawyers and judges would be out of jobs quickly. Technology is complex, also. This results in a tendency (maybe even a compulsion) among patent attorneys and courts deciding patent cases to analogize to other areas of the law, to shoehorn fact into narrow doctrines, or otherwise to do things that reduce the case and the technology at …

From Bibles To Biomarkers: The Future Of The Dsm And Forensic Psychiatric Diagnosis, Teneille R. Brown

Utah Law Faculty Scholarship

Given its importance to the law, it is regrettable that judges and lawyers do not fully understand how the DSM is constructed, and the bedrock of values on which it rests. As evidence of this, lawyers and judges often refer to the DSM as the “psychiatric bible.” This language is both fascinating and perplexing. This Article will attempt to correct the notion that the DSM is a legal “psychiatric bible” by explaining how it is created and used by the medical field. It will also provide a few reasons why the law may have come to view it as a …

Brougham’S Ghost, Michael S. Ariens

Faculty Articles

In defending Queen Caroline in the House of Lords, Henry Brougham declared, “[a]n advocate, by the sacred duty of his connection with his client, knows, in the discharge of that office, but one person in the world, that client and none other.” Brougham’s ethic of advocacy has been cited repeatedly as stating the American lawyer’s duty of zealous representation of a client. It has often been called the “classic statement” of zealous representation and representing the “traditional view of the lawyer’s role.”

This essay challenges these conclusions. Brougham’s rhetoric was neither a classic statement of the duty of loyalty to …

5-Hydroxytryptamine Receptor (5-Ht1dR) Promotes Colorectal Cancer Metastasis By Regulating Axin1/Β-Catenin/Mmp-7 Signaling Pathway, Hua Sui, Hanchen Xu, Qing Ji, Xuan Liu, Lihong Zhou, Haiyan Song, Xiqiu Zhou, Yangxian Xu, Zhesheng Chen, Jianfeng Cai, Guang Ji, Qi Li

Chemistry Faculty Publications

Overexpression of 5-hydroxytryptamine (5-HT) in human cancer contributes to tumor metastasis, but the role of 5-HT receptor family in cancer has not been thoroughly explored. Here, we report overexpression of 5-HT_1D receptor (5-HT_1DR) was associated with Wnt signaling pathway and advanced tumor stage. The underlying mechanism of 5-HT_1DR-promoted tumor invasion was through its activation on the Axin1/β-catenin/MMP-7 pathway. In an orthotopic colorectal cancer mouse model, we demonstrated that a 5-HT_1DR antagonist (GR127935) effectively inhibited tumor metastasis through targeting Axin1. Furthermore, in intestinal epithelium cells, we observed that 5-HT_1DR played an important …

Inhibition Of Shp2 Suppresses Mutant Egfr-Induced Lung Tumors In Transgenic Mouse Model Of Lung Adenocarcinoma, Valentina E. Schneeberger, Yuan Ren, Noreen Luetteke, Qingling Huang, Liwei Chen, Harshani R. Lawrence, Nicholas J. Lawrence, Eric B. Haura, John M. Koomen, Domenico Coppola, Jie Wu

Molecular Biosciences Faculty Publications

Epidermal growth factor receptor (EGFR) mutants drive lung tumorigenesis and are targeted for therapy. However, resistance to EGFR inhibitors has been observed, in which the mutant EGFR remains active. Thus, it is important to uncover mediators of EGFR mutant-driven lung tumors to develop new treatment strategies. The protein tyrosine phosphatase (PTP) Shp2 mediates EGF signaling. Nevertheless, it is unclear if Shp2 is activated by oncogenic EGFR mutants in lung carcinoma or if inhibiting the Shp2 PTP activity can suppress EGFR mutant-induced lung adenocarcinoma. Here, we generated transgenic mice containing a doxycycline (Dox)-inducible PTP-defective Shp2 mutant (tetO-Shp2CSDA). Using the rat Clara …

The Νsaα Specific Lipoprotein Like Cluster (Lpl) Of S. Aureus Usa300 Contributes To Immune Stimulation And Invasion In Human Cells, Minh Thu Nguyen, Beatrice Kraft, Wenqi Yu, Dogan Doruk Demicrioglu, Tobias Hertlein, Marc Burian, Mathias Schmaler, Klaus Boller, Isabelle Bekeredjian-Ding, Knut Ohlsen, Birgit Schittek, Friedrich Götz

Molecular Biosciences Faculty Publications

All Staphylococcus aureus genomes contain a genomic island, which is termed νSaα and characterized by two clusters of tandem repeat sequences, i.e. the exotoxin (set) and 'lipoprotein-like' genes (lpl). Based on their structural similarities the νSaα islands have been classified as type I to IV. The genomes of highly pathogenic and particularly epidemic S. aureus strains (USA300, N315, Mu50, NCTC8325, Newman, COL, JH1 or JH9) belonging to the clonal complexes CC5 and CC8 bear a type I νSaα island. Since the contribution of the lpl gene cluster encoded in the νSaα island to virulence is unclear to date, we deleted …

Ecology, Population Dynamics, And Sexual Characteristics Of Commensal Leucothoid Amphipods With The Sponge Cliona Varians In The Florida Keys (Crustacea: Amphipoda), Stephanie Lynn Andringa

HCNSO Student Theses and Dissertations

Recent observations have identified a new species of leucothoid amphipod, Leucothoe “sp. F,” associated with the sponge Cliona varians. This project examined the relationship between this amphipod and its sponge host at three sites in the Florida Keys with differing hydrodynamic regimes. Ninety-eight sponge samples with a total of 2,030 amphipods were collected between December 2011 and September 2012. Leucothoe “sp. F” is currently a common species in the Florida Keys strongly associated with C. varians; its distribution strongly coincides with open tidal currents from the Gulf of Mexico. Seasonality, depth, and tidal regimes not only influence population …

Caffeine Elicits Time Dependent Biphasic Response Of Functional Recovery In Carassius Auratus Hemilabyrinthectomy Lesion Model, Bethany Brockhoff

HCNSO Student Theses and Dissertations

Caffeine is one of the most popular psychostimulant drugs worldwide. Its effects are exerted through a variety of complex mechanisms, apparently primarily via interactions with adenosine A1 and A2A receptors. This drug has also been proven to elicit neuroprotective responses in a number of different brain disorders of the Central Nervous System (CNS), as well as provide enhancement of cognitive abilities. Moreover, a biphasic set of functional and structural neurological changes are often found in these receptors among diverse vertebrates. I investigated the effects of chronic caffeine exposure on functional recovery of the dorsal light reflex (DLR) in hemilabyrinthectomized common …

Ebola Cases And Health System Demand In Liberia, John M. Drake, Rajreni B. Kaul, Laura W. Alexander, Suzanne M. O’Regan, Andrew M. Kramer, J. Tomlin Pulliam, Matthew J. Ferrari, Andrew W. Park

Integrative Biology Faculty and Staff Publications

In 2014, a major epidemic of human Ebola virus disease emerged in West Africa, where human-to-human transmission has now been sustained for greater than 12 months. In the summer of 2014, there was great uncertainty about the answers to several key policy questions concerning the path to containment. What is the relative importance of nosocomial transmission compared with community-acquired infection? How much must hospital capacity increase to provide care for the anticipated patient burden? To which interventions will Ebola transmission be most responsive? What must be done to achieve containment? In recent years, epidemic models have been used to guide …

Undergraduate Research Experience Aids Progression, Graduation Rates At Texas Southern University, David Owerbach

Office of Research Institutional Research and Scholarship

Undergraduate research experiences have become a widely accepted goal of colleges and universities for enhancing student development and success. Texas Southern University (TSU) is an Historically Black College and University (HBCU) with approximately 6,000 undergraduate students and as with most HBCUs, retention and graduation rates are extremely low. This study addresses the relationship between undergraduate research at TSU and progression, graduation rates and GPA. The experimental population includes 34 students that participated at a 10-week undergraduate research program (URP) during the summers of 2012 or 2013. The control group was selected from the 2006 freshmen class (n=268) admitted to the …

Comparative Metal Oxide Nanoparticle Toxicity Using Embryonic Zebrafish, Leah C. Wehmas, Catherine Anders, Jordan Chess, Alex Punnoose, Cliff B. Pereira, Juliet A. Greenwood, Robert L. Tanguay

Physics Faculty Publications and Presentations

Engineered metal oxide nanoparticles (MO NPs) are finding increasing utility in the medical fields as anticancer agents. Before validation of in vivo anticancer efficacy can occur, a better understanding of whole-animal toxicity is required. We compared the toxicity of seven widely used semiconductor MO NPs made from zinc oxide (ZnO), titanium dioxide, cerium dioxide and tin dioxide prepared in pure water and in synthetic seawater using a five-day embryonic zebrafish assay. We hypothesized that the toxicity of these engineered MO NPs would depend on physicochemical properties. Significant agglomeration of MO NPs in aqueous solutions is common making it challenging to …

The Relevance Of Maize Pollen For Assessing The Extent Of Maize Production In Chaco Canyon, Carrie C. Heitman, Phil R. Geib

Department of Anthropology: Faculty Publications

Opinion is hardly unanimous, but many authors endorse the idea that Chaco Canyon is and was a marginal place for growing corn (Zea mays), a chief source of food energy for Puebloan groups in the Southwest. Poor soils with “toxic” levels of salts, inadequate and unpredictable precipitation, and a short growing season have all been identified as contributing to the agricultural marginality of the place (Benson 2011a; Bryan 1954; Force et al. 2002; Judd 1954:59–61). Benson has been the most vocal proponent of this view of late, and his research has culminated in the conclusion that “the San Juan Basin, …

Case Study: Producer Concerns And Perceptions Regarding The Effect Of Methane On Cattle Production And The Environment: A Survey Of Nebraska Producers, B. M. Boyd, A. Jones, Lisa Franzen-Castle, K. Jenkins, Richard J. Rasby, Matt K. Luebbe, Richard R. Stowell, Samodha C. Fernando, Galen E. Erickson

Department of Animal Science: Faculty Publications

Enteric methane production from cattle and its effect on climate change has been a topic of debate. Multiple studies have explored methods to reduce cattle enteric methane production while simultaneously improving performance. However, most strategies developed have not been widely implemented by cattle producers. Knowledge of producer concerns and perceptions on methane production from cattle and its effect on the environment may be limited. Therefore, the objectives of this survey were to determine what Nebraska producers know about methane production by cattle and how it affects performance and to determine whether different age groups, regions of Nebraska, and production size …

Development Of A Row-Crop Tractor Data Acquisition System, James Roeber, Santosh Pitla, Roger M. Hoy, Joe D. Luck

Department of Animal Science: Faculty Publications

Numerous advancements in machinery performance on row-crop agricultural tractors have been made in recent years. Currently, the Organisation for Economic Co-operation and Development (OECD) only tests predetermined points (E.g., max. power, max. torque) for drawbar and hydraulic power. This method of testing has been used for many years with the tractor at a steady state which is usually not typical of row-crop operations. A data acquisition system (DAQ) was designed that records implement energy consumption (E.g., drawbar loading, PTO power, and hydraulic power). The system used a LabVIEW program and a compact data acquisition system (cDAQ) to record data from …

An Application Of Mesh Enrichment Analysis In Livestock, Gota Morota, F. Moreno, James L. Petersen, Daniel C. Ciobanu, K. Tsuyuzaki, I. Nikaido

Department of Animal Science: Faculty Publications

An integral part of functional genomics studies is to assess the enrichment of specific biological terms in lists of genes found to be playing an important role in biological phenomena. Contrasting the observed frequency of annotated terms with those of the background is at the core of overrepresentation analysis (ORA). Gene Ontology (GO) is a means to consistently classify and annotate gene products and has become a mainstay in ORA. Alternatively, Medical Subject Headings (MeSH) offers a comprehensive life science vocabulary including additional categories that are not covered by GO. Although MeSH is applied predominantly in human and model organism …

Microbial Diversity And Activity In The Nematostella Vectensis Holobiont: Insights From 16s Rrna Gene Sequencing, Isolate Genomes, And A Pilot-Scale Survey Of Gene Expression, Jia Y. Har, Tim Helbig, Ju H. Lim, Samodha C. Fernando, Adam M. Reitzel, Kevin Penn, Janelle R. Thompson

Department of Animal Science: Faculty Publications

We have characterized the molecular and genomic diversity of the microbiota of the starlet sea anemone Nematostella vectensis, a cnidarian model for comparative developmental and functional biology and a year-round inhabitant of temperate salt marshes. Molecular phylogenetic analysis of 16S rRNA gene clone libraries revealed four ribotypes associated with N. vectensis at multiple locations and times. These associates include two novel ribotypes within the ε-Proteobacterial order Campylobacterales and the Spirochetes, respectively, each sharing 99% 16S rRNA identity with Endozoicomonas elysicola and Pseudomonas oleovorans, respectively. Species-specific PCR revealed that these populations persisted in N. vectensis asecually propagated under laboratory …

Presencia De Metales Pesados En La Reserva De La Biosfera Barranca De Metztitlán, Hidalgo, México, Irving Giovanny González-Salazar, Maritza López-Herrera, Scott Monks, Griselda Pulido-Flores

Estudios en Biodiversidad

La Reserva de la Biosfera Barranca de Metztitlán es un área natural protegida por la gran diversidad de flora y fauna existente en la misma. La zona es atravesada por un río de gran longitud que se extiende desde el municipio de Tulancingo hasta su desembocadura en la Laguna de Metztitlán, en la zona núcleo de la reserva. A lo largo del cauce del río se ubican algunos asentamientos humanos y zonas industriales, que vierten aguas residuales domésticas e industriales. Además, el agua del río es un recurso natural utilizado como agua de riego para las zonas agrícolas, que con …

Percepción De Calidad De Vida, Contaminación Y Riesgo En Localidades Rurales Del Municipio De Tecoanapa, Guerrero, Rocío López-Velasco, América Rodríguez-Herrera, Humberto González-González, Branly Olivier-Salomé, Consuelo Montalvo-Marques

Estudios en Biodiversidad

En el presente trabajo se realizó un análisis sobre la percepción de calidad de vida, contaminación y riesgo en nueve comunidades rurales del Municipio de Tecoanapa, Guerrero. Para ello, se seleccionaron nueve comunidades que cumplieran con tres aspectos: rezago social (muy alto, medio y muy bajo); ubicación (cerca de ríos); y vivencias en conflictos y embates ambientales. Se levantó una encuesta a jefes de familia en febrero de 2014. Registrando que el 70% de los habitantes afirmaron tener una buena calidad de vida. Al cuestionarlos sobre contaminación, el 59.9% consideró que si existe y está asociada al agua. El 52.0% …

Plantas Útiles De Tres Municipios (Metztitlán, Atotonilco El Grande Y Huasca De Ocampo) De La Reserva De La Biosfera Barranca De Metztitlán, Hidalgo, México, Miguel Ángel Villavicencio-Nieto, Blanca Estela Pérez-Escandón, Berenice N. López-Gutiérrez

Estudios en Biodiversidad

Existen muy pocos trabajos etnobotánicos realizados en la Reserva de la Biosfera Barranca de Metztitlán, por lo que el objetivo de este estudio fue generar un listado preliminar de plantas útiles de la Reserva. Se aplicaron entrevistas a habitantes de localidades ubicadas en la zona, para colectar las plantas útiles mencionadas se hicieron recorridos de campo en compañía de informantes, posteriormente las especies fueron identificadas con el uso de claves dicotómicas. Se registraron 83 especies de plantas útiles, distribuidas en 39 familias y 20 categorías de uso, siendo la medicinal la mejor representada por número de especies. Conocer el uso …