Digital Commons Network^™

Clear Cell Renal Cell Carcinoma With Borderline Features Of Clear Cell Papillary Renal Cell Carcinoma: Combined Morphologic, Immunohistochemical, And Cytogenetic Analysis, Sean R. Williamson, Nilesh S. Gupta, John N. Eble, Craig G. Rogers, Susan Michalowski, Shaobo Zhang, Mingsheng Wang, David J. Grignon, Liang Cheng

Pathology and Laboratory Medicine Articles

Clear cell papillary renal cell carcinoma is increasingly recognized as a distinct tumor with unique morphology, immunohistochemistry, and cytogenetics. Histopathology often mimics clear cell renal cell carcinoma; however, metastasis has not been reported, emphasizing the clinical value of recognizing these likely nonaggressive tumors. We studied tumors with borderline morphology of clear cell papillary renal cell carcinoma, utilizing immunohistochemistry and fluorescence in situ hybridization or karyotyping. Tumors from 22 patients (ages 33 to 82 y) were analyzed. Clear cell papillary renal cell carcinoma-like morphology varied from 10% to 90% of the tumor (median 25%). Sources of resemblance included: branched glands (95%), …

Alternative Courts And Drug Treatment: Finding A Rehabilitative Solution For Addicts In A Retributive System, Molly K. Webster

Fordham Law Review

    Sentencing drug crimes and treating drug-addicted defendants often stem from contradictory theories of punishment. In the late twentieth century, courts traded rehabilitation for retributive ideals to fight the “War on Drugs.” However, beginning with the Miami-Dade Drug Court, treatment and rehabilitation have returned to the forefront of sentencing policy in traditional and alternative drug courts.

    Jurisdictions have implemented a variety of policies designed to treat addiction as opposed to punishing it. Community courts, such as the Red Hook Community Justice Center in Brooklyn, New York, community-panel drug courts, such as the Woodbury County Community Drug Court in Iowa, and Hawaii’s …

Factors Contributing To Students Seeking An Alternative Secondary School Setting, Brian Crawford

Doctor of Education (EdD)

This is a case study of six students who chose to leave a comprehensive high school that has a reputation for academic excellence. Through a triangulation of data from semi-structured private interviews with the students and their school counselors and the students’ academic records, the details of the students’ experiences at a high school exposed some of the personal factors and school-based factors that influenced their decision to leave. All of these students struggled academically, socially, or emotionally. The major thematic categories for reasons the students left that emerged from the interviews were student mobility, mental illness, socio-economic pressure, academic …

Concentration-Independent Mri Of Ph With A Dendrimer-Based Ph-Responsive Nanoprobe, Mohammed Pi Bhuiyan, Madhava P. Aryal, Branislava Janic, Kishor Karki, Nadimpalli Rs Varma, James R. Ewing, Ali S. Arbab, Meser M. Ali

Neurology Articles

The measurement of extracellular pH (pHe ) has significant clinical value for pathological diagnoses and for monitoring the effects of pH-altering therapies. One of the major problems of measuring pHe with a relaxation-based MRI contrast agent is that the longitudinal relaxivity depends on both pH and the concentration of the agent, requiring the use of a second pH-unresponsive agent to measure the concentration. Here we tested the feasibility of measuring pH with a relaxation-based dendritic MRI contrast agent in a concentration-independent manner at clinically relevant field strengths. The transverse and longitudinal relaxation times in solutions of the contrast agent (GdDOTA-4AmP)44 …

Identification Of Regions Of Normal Grey Matter And White Matter From Pathologic Glioblastoma And Necrosis In Frozen Sections Using Raman Imaging, Rachel Kast, Gregory Auner, Sally Yurgelevic, Brandy Broadbent, Aditya Raghunathan, Laila M. Poisson, Tom Mikkelsen, Mark L. Rosenblum, Steven N. Kalkanis

Neurosurgery Articles

In neurosurgical applications, a tool capable of distinguishing grey matter, white matter, and areas of tumor and/or necrosis in near-real time could greatly aid in tumor resection decision making. Raman spectroscopy is a non-destructive spectroscopic technique which provides molecular information about the tissue under examination based on the vibrational properties of the constituent molecules. With careful measurement and data processing, a spatial step and repeat acquisition of Raman spectra can be used to create Raman images. Forty frozen brain tissue sections were imaged in their entirety using a 300-µm-square measurement grid, and two or more regions of interest within each …

Inquiry-Based Experiments For Large-Scale Introduction To Pcr And Eestriction Enzyme Digests, Kelly E. Johanson, Terry J. Watt

Faculty and Staff Publications

Polymerase chain reaction and restriction endonuclease digest are important techniques that should be included in all Biochemistry and Molecular Biology laboratory curriculums. These techniques are frequently taught at an advanced level, requiring many hours of student and faculty time. Here we present two inquiry-based experiments that are designed for introductory laboratory courses and combine both techniques. In both approaches, students must determine the identity of an unknown DNA sequence, either a gene sequence or a primer sequence, based on a combination of PCR product size and restriction digest pattern. The experimental design is flexible, and can be adapted based on …

Residual Impact Of Previous Injury On Musculoskeletal Characteristics In Special Forces Operators, Jeffrey J. Parr, Nicholas C. Clark, John P. Abt, Julie Y. Kresta, Karen A. Keenan, Shawn F Kane, Scott M. Lephart

Physical Therapy Faculty Publications

Background: Musculoskeletal injuries are a significant burden to United States Army Special Operations Forces. The advanced tactical skill level and physical training required of Army Special Operators highlights the need to optimize musculoskeletal characteristics to reduce the likelihood of suffering a recurrent injury.

Purpose: To identify the residual impact of previous injury on musculoskeletal characteristics.

Study Design: Cross-sectional study; Level of evidence, 3.

Methods: Isokinetic strength of the knee, shoulder, and back and flexibility of the shoulder and hamstrings were assessed as part of a comprehensive human performance protocol, and self-reported musculoskeletal injury history was obtained. Subjects were stratified based …

Disaster Preparedness Education And Resource Needs For Pregnant And Post-Partum Families, Ellen A. Erickson Bonner

Nursing Theses and Dissertations

Hurricane Katrina in 2005 heightened awareness of the need to educate vulnerable populations on disaster preparedness. However, little has been written specifically on the preparedness needs of the pregnant and post-partum families. Only one article explores disaster preparedness education for this population. To fill this gap. An interprofessional sample (n=115) rated the relevance of the educational topics and birthing kit items proposed by the panel from the previous Delphi study. The education topics were reduced to four themes that explained 66.80% of the variance and the birthing kit items were reduced to six themes that explained 70.99% of the variance.

Technostress Effects On Technology Acceptance By Nurse Faculty, Joseph W. Tacy

Nursing Theses and Dissertations

Technology is an essential tool used in nursing academia. The rapid changes in technology and required adaptations can result in technostress, but little research exists about technostress among nurse educators. Gaps in this area of research generated several questions regarding the adaption to technology among nurse faculty and the impact technology has on stress, system use, job satisfaction, and intent to stay in the profession. This dissertation explored technostress and its influence on technology use, acceptance, job satisfaction, and intention to stay within the profession. Included are two manuscripts. The first is a concept analysis of technostress. The second manuscript …

Intergenerational Challenges In Teaching & Learning, Danice B. Greer, Melinda Hermanns

Nursing Faculty Publications and Presentations

This presentation discusses the challenges with teaching and learning students of varying generations. Solutions, including a Strength-based approach to teaching, are provided to give guidance on working with intergenerational students.

Police Violence And Ferguson: (En)Racing Criminal Procedure, Jeannine Bell

Journal of Legal Education

No abstract provided.

Que Ondee Sola - November 2015, Juan Morales

Que Ondee Sola

Student publication founded in 1972, articles include: The Weapon of Poetry, El Sueno Americana- The American Dream, Puerto Rican Education and Social Justice: Promoting Transformative and Emancipatory Forms of Knowledge, The Face of the Puerto Rican Diaspora is manifested in Orlando, Student ACCESS Bill Campaign Launch, Three Cities One Voice National Lawyers Guild Annual Conference, Can We Imagine?, Semilla's Fight for Women's Rights from Chicago to Mexico

Panorama November 2015, Southern Adventist University

Panorama Parent Newsletter

This issue of the Panorama parent newsletter discusses working with mentors and advisers, highlights the LEAP alumni mentor program, includes a staff profile on Career Counselor Daniel Olson, and highlights student mentors.

November 2015 Quicknotes, Southern Adventist University

QuickNotes – Advancement e-Newsletter

QuickNotes is an e-newsletter that comes from Advancement at Southern Adventist University. November 2015 edition features the article "Advancement Welcomes New VP".

A Path To Empathy: Child And Family Communication, Sarah Ann Stone

Theses and Dissertations

This longitudinal study examined the association between communication in the family on the development of empathy in young children. Co-regulation and family expressiveness measured communication in parent-child dyads at age 12 months (N = 186), 24 months (N = 100), and 36 months (N = 78). A follow-up was conducted at 60 months (N = 47) to measure empathy-related responding in children. Co-regulation styles change over time, generally increasing in the most engaged, two-way style of communication (symmetrical) and decreasing in one-sided and less engaged types. Greater family expressiveness predicted higher levels of empathy as observed in an empathy-eliciting experiment, …

Alternating Direction Implicit Method With Adaptive Grids For Modeling Chemotaxis In Dictyostelium Discoideum, Christopher F. Loomis

Theses and Dissertations

Dictyostelium discoideum (Dd) is a model organism, studied for reasons from cell movement to chemotaxis to human disease control. Creating a computer model of the life cycle of Dd has garnered great interest, one part of which is the Aggregation Stage, where thousands of amoeba gather together to form a slug. Chemotaxis is the mechanism through which this is accomplished. This thesis develops two- and three-dimensional alternating direction implicit code which solves the diffusion equation on an adaptive grid. The calculated values for both two and three dimensions are checked against the actual solution and error results are provided. Comparisons …

The Homeoprotein Dlx3 And Tumor Suppressor P53 Co-Regulate Cell Cycle Progression And Squamous Tumor Growth, Paul W. Bible, E. Palazzo, M. Kellett, C. Cataisson, A. Gormley, V. Pietroni, Et Al.

Computer Science Faculty publications

Epidermal homeostasis depends on the coordinated control of keratinocyte cell cycle. Differentiation and the alteration of this balance can result in neoplastic development. Here we report on a novel DLX3-dependent network that constrains epidermal hyperplasia and squamous tumorigenesis. By integrating genetic and transcriptomic approaches, we demonstrate that DLX3 operates through a p53-regulated network. DLX3 and p53 physically interact on the p21 promoter to enhance p21 expression. Elevating DLX3 in keratinocytes produces a G1-S blockade associated with p53 signature transcriptional profiles. In contrast, DLX3 loss promotes a mitogenic phenotype associated with constitutive activation of ERK. DLX3 expression is lost in human …

The Impact Of Immobile Zones On The Transport And Retention Of Nanoparticles In Porous Media, Ian L. Molnar, Jason I. Gerhard, Clinton S. Willson, Denis M. O'Carroll

Faculty Publications

Nanoparticle transport and retention within porous media is treated by conceptualizing the porous media as a series of independent collectors (e.g., Colloid Filtration Theory). This conceptualization assumes that flow phenomena near grain-grain contacts, such as immobile zones (areas of low flow), exert a negligible influence on nanoparticle transport and assumes that retention and release of particles depends only on surface chemistry. This study investigated the impact of immobile zones on nanoparticle transport and retention by employing synchrotron X-ray computed microtomography (SXCMT) to examine pore-scale silver nanoparticle distributions during transport through three sand columns: uniform iron oxide, uniform quartz, and well-graded …

Hypercalcemia Of Malignancy: An Update On Pathogenesis And Management, Aibek E. Mirrakhimov

Internal Medicine Faculty Publications

Hypercalcemia of malignancy is a common finding typically found in patients with advanced stage cancers. We aimed to provide an updated review on the etiology, pathogenesis, clinical presentation, and management of malignancy-related hypercalcemia. We searched PubMed/Medline, Scopus, Embase, and Web of Science for original articles, case reports, and case series articles focused on hypercalcemia of malignancy published from 1950 to December 2014. Hypercalcemia of malignancy usually presents with markedly elevated calcium levels and therefore, usually severely symptomatic. Several major mechanisms are responsible for the development of hypercalcemia of malignancy including parathyroid hormone-related peptide-mediated humoral hypercalcemia, osteolytic metastases-related hypercalcemia, 1,25 Vitamin …

The Heart Failure Overweight/Obesity Survival Paradox : The Missing Sex Link, Amanda R. Vest, Yuping Wu, Roy Hachamovitch, James B. Young, Leslie Cho

Mathematics and Statistics Faculty Publications

Objectives: This study sought to determine whether body mass index (BMI) has a differential impact on survival for females versus males with advanced systolic heart failure (HF). Background: Females have a survival advantage in HF, the mechanisms of which are unclear. There is also a proposed “obesity survival paradox” in which excess adiposity promotes HF survival. Methods: We reviewed 3,811 patients with left ventricular ejection fraction ≤40% who had undergone cardiopulmonary exercise testing between 1995 and 2011. The endpoint was all-cause mortality. Multivariable analysis was performed using a Cox proportional hazards model. Because of the nonlinearity of BMI, a restricted …

Urbanisation, Technology, And The Growth Of Smart Cities, Parag Khanna

Asian Management Insights

The dual trend of rapid urbanisation and sophistication of technology will eventually give rise to smart cities around the world. As new challenges emerge, what are Asian cities doing to ensure their success in the future?

คำขอบคุณ, N/A

Chulalongkorn Medical Journal

No abstract provided.

Mckee Minute November 2015, Southern Adventist University

McKee Minute – McKee Library This Month

The November 2015 McKee Minute features several books on "The History & Mystery of Time," including The Little Book of Time by Klaus Mainzer and Splitting the Second by Tony Jones. Featured films include The Adventures of Huck Finn and The Life and Work of Mark Twain. Featured Adventist periodicals include Adventist Frontiers and Journal of Adventist Education. This month's spotlight is on chemistry.

Ipulse: November 2015, Lynn University

Student Newspapers

Issues:

• November 2, 2015
• November 4, 2015
• November 6, 2015
• November 11, 2015
• November 13, 2015
• November 16, 2015
• November 18, 2015
• November 20, 2015
• November 30, 2015

Clinical Utility Of Dabigatran In United Arab Emirates: A Pharmacovigilance Study, Abdulla Shehab, Asim A. Elnour, Adel Sadik, Mahmoud Abu Mandil, Ali Alshamsi, Aesha Al Suwaidi, Akshayasrikanth Bhagavathula, Pinar Erkekoglu, Farah Hamad

Saudi Medical Journal

Objectives: To provide early data regarding clinical utility of dabigatran in Al-Ain, United Arab Emirates (UAE). Methods: This was an ethics approved retrospective cross sectional study. We retrieved a total of 76 patients who were using dabigatran from September to December 2014 in the Cardiology Clinic at Al-Ain Hospital, Al-Ain, UAE. The primary analysis was designed to test the frequency of bleeding events (rate) with dabigatran 75, 110, and 150 mg. Results: The mean age ± standard deviation of cohort was 67.9 ± 1.5 years (range; 29-98 years), composed of males (52.6%) with mean age of 66.3 ± 1.7 years, …

Osteoporosis Treatment With Zoledronic Acid In Pediatric Population At A University Hospital In Western Saudi Arabia: A 13-Year Experience, Abdulmoein E. Al-Agha, Rahaf S. Hayatalhazmi

Saudi Medical Journal

Objectives: To highlight the clinical benefit, efficacy, and safety of zoledronic acid (ZA) therapy in children and adolescents with primary and secondary osteoporosis. Methods: This is a retrospective observational study of 131 children and adolescents visiting the Pediatric Endocrine Clinic at King Abdulaziz University Hospital, Jeddah, Kingdom of Saudi Arabia, between January 2002 and January 2015. Clinical and laboratory data were collected for each patient and adverse events were evaluated. Results: The mean patient age was 11.43 years. There was a significant decrease in the number of fractures after ZA treatment for primary osteoporosis ( p =0.000) and in secondary …

Meaning In Life In Psychotherapy: The Perspective Of Experienced Psychotherapists, Clara E. Hill, Yoshi Kanazawa, Sarah Knox, Iris Schauerman, Darren Loureiro, Danielle James, Imani Carter, Shakeena King, Suad Razzak, Melanie Scarff, Jasmine Moore

College of Education Faculty Research and Publications

Objective

Our goal was to explore the meaning experienced psychotherapists derive from providing psychotherapy, their beliefs about the role of meaning in life (MIL) in psychotherapy, how they worked with MIL with a client who explicitly presented concerns about MIL, and how they worked with a different client for whom MIL was a secondary and more implicit concern.

Method

Thirteen experienced psychotherapists were interviewed and data were analyzed using consensual qualitative research.

Results

Therapists derived self-oriented meaning (e.g., feeling gratified, fulfilled, connected) and other-oriented meaning (helping others, making the world a better place) from providing psychotherapy. They believed that MIL …

Civic Play And Civic Gaps: Can Life Simulation Games Advance Educational Equity?, Christine Bachen, Pedro F. Hernández-Ramos, Chad Raphael, Amanda Waldron

Communication

Digital games and simulations (DG&S) could help mitigate inequities in civic education and participation, which are found in many contemporary democracies. Yet incorporating DG&S into the curriculum may reinforce or introduce inequities for students who are less engaged by game-based learning. A quasi-experimental study of 301 U.S. high school students in social studies classes examined whether prior academic performance, civic engagement, civic game play experience and gender affected how (and which) students benefit from playing a life simulation game. Dependent variables included several civic dispositions: justice-oriented citizenship norms and interest in politics, news, and global issues. The simulation game especially …

Tri-Ag Academics Research Extension College Of Agriculture Sciences - November 2015, Prairie View A&M University

Prairie View Magazine Collection

No abstract provided.

Copyright And The Digitization Of State Government Documents: A Preliminary Analysis, Brett D. Currier, David Hansen, Anne Gilliland

UTA Libraries Staff Publications - Archive

In this paper we explore the copyright status of state and local government documents and address some of the legal issues encountered when digitizing them.