Digital Commons Network^™

Aspirin Triggered Resolution Phase Interaction Product D1: A Novel Treatment For Hyperoxic Acute Lung Injury, Ruan Rollin Cox, Jr.

USF Tampa Graduate Theses and Dissertations

Acute Lung injury (ALI) and the more severe acute respiratory distress syndrome (ARDS) are respiratory maladies that present immense clinical challenges. ALI affects 200,000 individuals annually and features a 40% mortality rate. ALI can be initiated by both pathogenic and sterile insults originating locally in the lungs or systemically. While immense research has been poured into this disease in an effort to find a therapeutic strategy, the heterogeneously diffuse nature of the disease has not yielded a cure for the disease. Death from this disease is strongly attributed to reduced gas exchange from a severely compromised alveolar-capillary barrier. The only …

Interview With Anne Porcher Perrin And Daughter, Anne Perrin Flynn, Anne Porcher Perrin, Anne Perrin Flynn

South Carolina Mother of the Year Oral History Archives

Interview with Anne Porcher Perrin, member of the South Carolina Mothers Association and South Carolina Mother of the Year Selection Committee, and Anne Perrin Flynn, member of the South Carolina Mothers Association.

Faunal Data For Pleistocene-Holocene Archaeological Sites In Thailand And Peninsular Malaysia, Cyler Conrad

Anthropology Datasets

Faunal data, R script and figures are provided as a zip file (OQ_SEA-master.zip) created from the repository hosted at https://github.com/cylerc/OQ_SEA. Within this zip file there is a folder called “data,” where all summary and raw faunal counts are included. Original citation information from which this data is derived is included in the Readme document. Tables are presented as number of identified specimens (NISP), minimum number of individuals (MNI) or presence/absence data within each .csv. Column headings represent stratigraphic units or contexts that the original publications use. x=classification present in context/unit. In Thailand, zooarchaeological data is included from Spirit Cave, Banyan …

Medical School Watercooler Newsletter - July 12, 2015, Lindsey Lyle

Watercooler Newsletter

This is the July 12, 2015 edition of the Frederick P. Whiddon College of Medicine's Newsletter - Watercooler.

Contents Include:

Grant Award Allows for Creation of NICU Family Resource Center

USA Center for Healthy Communities Center of Excellence Hosts Regional Health Disparities Symposium

USA Medical Student Returns From NIH Medical Research Scholars Program

Tobacco Cessation: Why Quit?

July 11, 2015 (Pages 3699-3788), Pennsylvania Legislative Reference Bureau

Volume 45 (2015)

No abstract provided.

Low And Moderate Prenatal Ethanol Exposure Of Mice During Gastrulation Or Neurulation Delays Neurobehavioral Development, Uta B. Schambra, Jeff Goldsmith, Kevin Nunley, Yali Liu, Sam Harirforoosh, Heidi M. Schambra

Pharmacy Faculty Articles and Research

Human and animal studies show significant delays in neurobehavioral development in offspring after prolonged prenatal exposure to moderate and high ethanol doses resulting in high blood alcohol concentration (BECs). However, none have investigated the effects of lower ethanol doses given acutely during specific developmental time periods. Here, we sought to create a mouse model for modest and circumscribed human drinking during the 3rd and 4th weeks of pregnancy.

We acutely treated mice during embryo gastrulation on gestational day (GD) 7 or neurulation on GD8 with a low or moderate ethanol dose given via gavage that resulted in BECs of 107 …

Formulation And In Vivo Evaluation Of Aliskiren-Loaded Poly(Lactic-Co-Glycolic) Acid Nanoparticles, Derek E. Murrell, Jessica M. Coleman, Stacy D. Brown, Sam Harirforoosh

Pharmacy Faculty Articles and Research

Aliskiren (ALS) is a direct renin inhibitor with low bioavailability and high drug cost. The goal of this study was to increase the bioavailability of ALS through nanoformulation. The optimized formulation was then evaluated in spontaneously hypertensive rats (SHRs). We developed an ALS poly(lactic-co-glycolic) acid nanoparticle (ALS-NP) through the emulsion–diffusion–evaporation method with various solvents, stabilizer concentrations, and centrifugation speeds. SHRs were orally dosed with 30 mg/kg ALS or dose equivalent ALS-NP. Several parameters were assayed in plasma and/or urine at baseline and 24 h post-dose, while pharmacokinetic analysis included serial sampling. The optimum formulation was found with ethyl acetate, a …

Why A Fundamental Right To A Quality Education Is Not Enough, James Wilson

Akron Law Review

This article relies upon the political and economic analysis of such great thinkers as Aristotle and Rousseau to understand and normatively evaluate constitutional caselaw in general and education cases in particular. The article’s title contains its conclusion: a judicially created right to a quality education is a laudable, but possibly counterproductive and definitely insufficient condition, for creating a humane constitutional system. The rest of society needs to do far more to protect the average citizen and worker from the ever-ravenous ruling class. All the edification in the world will not mean much if there are only a few decent jobs …

Teaching Free Speech From An Incomplete Fossil Record, Michael Kent Curtis

Akron Law Review

The second part of this symposium has been devoted to how we teach the Constitution. It has emphasized what gets left out. The reader will see a pattern. Paul Finkelman is a leading scholar on the law of slavery and the Constitution. Paul thinks – and I believe he is correct – that the immense influence of slavery on American constitutional law is too often neglected in our constitutional law courses. James Wilson has studied how political philosophers – Aristotle, Rousseau, James Harrington, and others – have understood the distribution of wealth as a central factor affecting how the constitution …

The Contemporary Significance Of Meyer And Pierce For Parental Rights Issues Involving Education, William G. Ross

Akron Law Review

Despite their ringing declarations about human rights, Meyer and Pierce were both formally decided largely on the basis of property rights -- the liberty of the schools to conduct a business, the right of private school teachers to follow their occupation, and the freedom of the schools and the parents to enter into contracts. Although the Court easily could have decided the cases on the bases of freedom of religion or freedom of speech, the Court had not yet incorporated any part of the Bill of Rights into state law, and it was not prepared to begin the process of …

Free At Last? Charter Schools And The "Deregulated" Curriculum, Molly O'Brien

Akron Law Review

This paper will explore the prospects for charter school reform to provide curricular innovation and will point out several provisions in the legal organization of charter schools that will limit the possibilities for major innovation or radical reform of the official curriculum. This paper will also take stock of the autocratic and bureaucratic nature of the current public school model and weigh the possibility for charter schools to transform schools into places that embody democratic and community values. Charter schooling presents an exciting opportunity for school reform that rejects the factory model of public schooling and establishes both an official …

Can Post-Chicago Economics Survive Daubert?, Malcolm B. Coate, Jeffrey H. Fischer

Akron Law Review

In Section II of this Article, we review the Supreme Court’s standard for allowing expert testimony as explained in Daubert and related opinions, and discuss in detail the City of Tuscaloosa and Concord Boat decisions that, following Daubert, excluded the economic expert testimony on which the plaintiffs relied. Section III presents an overview of the Chicago School of Economics, which sets a foundation for our commentary on the Post-Chicago school and serves as a basis for the evaluation of Chicago-based testimony in Section V. Section IV discusses the Post-Chicago School approach to antitrust analysis as a refinement of the Chicago …

Get On Board For The Ride Of Your Life! The Ups, The Downs, The Twists, And The Turns Of The Applicability Of The "Gatekeeper" Function To Scientific And Non-Scientific Expert Evidence: Kumho'sexpansion Of Daubert, Leslie Morsek

Akron Law Review

This Comment examines the history of scientific and non-scientific expert evidence, its current status, and the future of scientific and non-scientific evidence based on recent court decisions. Part II explores the background of these issues by examining the earlier standard for admitting expert testimony, the effect of Congress’ promulgation of the Federal Rules of Evidence, and the influential cases in this area. Part III analyzes the importance of subjecting nonscientific expert testimony to the same rigors as scientific expert testimony. Lastly, Part IV predicts the future of expert evidence.

Is Justice For Sale In Ohio? An Examination Of Ohio Judicial Elections And Suggestions For Reform Focusing On The 2000 Race For The Ohio Supreme Court, Kara Baker

Akron Law Review

“Is justice for sale in Ohio?” asked a television advertisement in October 2000. Another advertisement informed voters that “today in Ohio, instructors teach and students learn, in spite of Justice Alice Resnick.” These advertisements are examples of the derogatory judicial campaigning that is becoming prevalent in the United States.

Part II of this comment will focus on the 2000 Ohio Supreme Court campaign between Alice Robie Resnick and Terrence O’Donnell as an example of current problems in judicial campaigning. The effect of this campaign and of similar other campaigns on the judicial system and public perceptions of justice will be …

Distinguishing The Concept Of Strict Liability For Ultra-Hazardous Activities From Strict Products Liability Under Section 402a Of The Restatement (Second) Of Torts: Two Parallel Lines Of Reasoning That Should Never Meet, Charles E. Cantu

Akron Law Review

The cornerstone of tort law in our Anglo-American system of jurisprudence is based upon three generally accepted principles. The first is that by awarding any individual monetary damages after their injury, we can make them whole, and the second is the concept of the reasonable prudent person. The third, and the focal point of this article, is that liability is imposed, and the corresponding right to recovery is created, not because of the fact that the plaintiff is injured, but because the injury is the result of the defendant’s fault.

Fault, as each first year law student is quick to …

Obituaries

Colby Magazine

No abstract provided.

Class Notes

Colby Magazine

No abstract provided.

Fishing For New Ways To Stop Parkinson's, A Researcher Makes Big Catches In The Gene Pool, Staff

Browse All News

No abstract provided.

Comparative Analysis Of Dietary Guidelines In The Spanish-Speaking Caribbean, Melissa Fuster

Publications and Research

Objective: Dietary guidelines are important education and policy tools to address local nutrition concerns. The current paper presents a comparative analysis of nutrition messages from three Spanish-speaking Caribbean countries (Cuba, Puerto Rico and Dominican Republic) to explore how these dietary guidelines address common public health nutrition concerns, contextualized in different changing food environments and food culture similarities.

Design: Qualitative, comparative analysis of current dietary guideline documents and key recommendations.

Results: Key recommendations were categorized into sixteen themes (two dietbased, ten food-based and four ‘other’). Only the Cuban dietary guidelines included diet-based key recommendations. Of the ten food-based …

Deep Characterization Of The Microbiomes Of Calophya Spp. (Hemiptera: Calophyidae) Gall-Inducing Psyllids Reveals The Absence Of Plant Pathogenic Bacteria And Three Dominant Endosymbionts, Will A. Overholt, Rodrigo Diaz, Erin Rosskopf, Stefan J. Green, William A. Overholt

Faculty Publications

© This is an open access article, free of all copyright, and may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose. The work is made available under the Creative Commons CC0 public domain dedication. Bacteria associated with sap-feeding insect herbivores include not only symbionts that may increase their hosts' fitness but also harmful plant pathogens. Calophya spp. gall-inducing psyllids (Hemiptera: Calophyidae) are being investigated for their potential as biological control agents of the noxious weed, Brazilian peppertree (Schinus terebinthifolia), in Florida. Although there are no examples of plant pathogen transmission by …

The Complexity Of Background Clutter Affects Nectar Bat Use Of Flower Odor And Shape Cues, Nathan Muchhala, Diana Serrano

Biology Department Faculty Works

Given their small size and high metabolism, nectar bats need to be able to quickly locate flowers during foraging bouts. Chiropterophilous plants depend on these bats for their reproduction, thus they also benefit if their flowers can be easily located, and we would expect that floral traits such as odor and shape have evolved to maximize detection by bats. However, relatively little is known about the importance of different floral cues during foraging bouts. In the present study, we undertook a set of flight cage experiments with two species of nectar bats (Anoura caudifer and A. geoffroyi) and artificial flowers …

The Road I'Ve Traveled: Who Said Grownups Have To Be Practical?, John Marshall

UNH Today Archive

No abstract provided.

The Murray Ledger And Times, July 10, 2015, The Murray Ledger And Times

The Murray Ledger & Times

No abstract provided.

The View From T-Hall: The Importance Of Public Service, Mark Huddleston

UNH Today Archive

No abstract provided.

Inquiring Minds, Beth Potier

UNH Today Archive

No abstract provided.

Molecular Overlap In The Regulation Of Sk Channels By Small Molecules And Phosphoinositides, Miao Zhang, Xuan-Yu Meng, Ji-Fang Zhang, Meng Cui, Diomedes E. Logothetis

Pharmacy Faculty Articles and Research

Phosphatidylinositol 4,5-bisphosphate (PIP2) directly interacts with the small-conductance Ca2+-activated K+ 2-a (SK2-a) channel/calmodulin complex, serving as a critical element in the regulation of channel activity. We report that changes of protein conformation in close proximity to the PIP2 binding site induced by a small-molecule SK channel modulator, NS309, can effectively enhance the interaction between the protein and PIP2 to potentiate channel activity. This novel modulation of PIP2 sensitivity by small-molecule drugs is likely not to be limited in its application to SK channels, representing an intriguing strategy to develop drugs controlling the activity of the large number of PIP2-dependent proteins.

Entire Issue Volume 5, Number 4

The Primary Source

Complete issue of Vol. 5, No. 4 of The Primary Source.

The Fourteenth Amendment: The Great Equalizer Of The American People, Abel A. Bartley

Akron Law Review

The Fourteenth Amendment to the United States Constitution, which was ratified on July 28, 1868, demonstrated the change in attitude, which hit many Americans after the chaotic Civil War. It was America’s first attempt to legally challenge White supremacist ideas by creating a truly equal multiracial society. With its emphasis on equal protection and equal justice, the Fourteenth Amendment was intended to be the great equalizer of American people, legally changing African American men into White men so that they could enjoy all the rights, privileges, and immunities of United States citizenship. However, determining the meaning of equality uncovered the …

The Constitutional Politics Of Interpreting Section 5 Of The Fourteenth Amendment, Christopher P. Banks

Akron Law Review

This essay analyzes the Rehnquist Court’s Section 5 cases by first, in Section I, establishing how the Supreme Court has historically assumed the task of interpreting Congress’ power to act under the Fourteenth Amendment. Two periods, Reconstruction and then the mid- 1960s, are examined because they present contrasting views about the scope of what the Fourteenth Amendment and its enforcement section means. Section II then surveys Section 5 cases from the Rehnquist Court in order to illustrate how its jurisprudence mirrors the antifederalist rhetoric established in the post-reconstruction era while, not surprisingly, departing from the principles set forth in the …

Rolling John Bingham In His Grave: The Rehnquist Court Makes Sport With The 14th Amendment, Stephen E. Gottlieb

Akron Law Review

The Warren Court organized the concept of strict scrutiny in Shelton v. Tucker. Where the defendant was obligated to treat people without regard to membership in a suspect class and failed to do that, the Court would hold them liable for their behavior unless it was done for a compelling public reason and there was no less damaging alternative.

The concept of strict scrutiny had nothing to do with intentions. The issue for the Warren Court was whether one party had injured another because of a forbidden reason. That concept of causation was understood broadly. The Court was not looking …