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2015

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Mobile Learning, John M. Traxler, Helen Crompton Jan 2015

Mobile Learning, John M. Traxler, Helen Crompton

Teaching & Learning Faculty Publications

No abstract provided.

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Perceptions Of Using Smart Mobile Devices In Higher Education Teaching: A Case Study From Palestine, Khitam Shraim, Helen Crompton Jan 2015

Perceptions Of Using Smart Mobile Devices In Higher Education Teaching: A Case Study From Palestine, Khitam Shraim, Helen Crompton

Teaching & Learning Faculty Publications

Smart mobile devices (SMDs), especially smartphones and tablets, are becoming increasingly ubiquitous among educators and students in Palestine. While their use is on the rise, many academics are not effectively incorporating this technology into their teaching, which may be attributable to their negative perceptions of these devices. This study therefore examined academics’ perceptions of the value of integrating SMDs into their teaching activities. A questionnaire survey collected data from 56 academic staff of the Palestine Technical University - Kadoorie, eliciting perceptions of the physical attributes of SMDs, participants’ self-efficacy, the pedagogical affordance of mobile devices and challenges to their use …

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Stat4 Regulates Multiple Pathogenic Mechanisms Of Cd4 T Cells In Experimental Autoimmune Encephalomyelitis, A Model Of Multiple Sclerosis, Ian Lee Mcwilliams Jan 2015

Stat4 Regulates Multiple Pathogenic Mechanisms Of Cd4 T Cells In Experimental Autoimmune Encephalomyelitis, A Model Of Multiple Sclerosis, Ian Lee Mcwilliams

All ETDs from UAB

Multiple Sclerosis (MS) is an autoimmune disease whereby the host immune system fails to recognize self vs non-self and targets myelin of the central nervous system. Currently there is no permanent cure for MS and the efficacy of immune modulatory treatments often wane over time, therefore we seek to determine novel pathogenic mechanisms to target therapeutically. CD4 T cells have been found within inflammatory CNS lesions of MS patients and are believed to be important mediators of MS pathology. To study CD4 T cells in the context of MS, we use the well-defined MS mouse model experimental autoimmune encephalomyelitis (EAE). …

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A Three Dimensional Microphysiologic Liver Model For Toxicity Testing, Lindsay Mckinney Miller Jan 2015

A Three Dimensional Microphysiologic Liver Model For Toxicity Testing, Lindsay Mckinney Miller

All ETDs from UAB

Drug development is an expensive and time consuming process, requiring an average of over $1 billion and up to fifteen years of work for each newly released product. Drug-induced liver toxicity is the leading cause of post-market drug withdrawals despite the fact that extensive animal testing and clinical trials are required prior to approval of a novel drug or therapy. Due to both the specificity and genetic variability of hepatic regulation and metabolism in humans, animal models and single-cell hepatocyte testing cannot fully predict the metabolic response of a novel compound. In vitro organ culture in a three dimensional (3D) …

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Innate Immunity Mechanisms In Parkinson Disease, Mark Moehle Jan 2015

Innate Immunity Mechanisms In Parkinson Disease, Mark Moehle

All ETDs from UAB

Parkinson disease (PD) is a late onset, progressive neurodegenerative movement disorder with cardinal symptoms of tremor at rest, bradykinesia, postural instability, and rigidity. These motor symptoms of PD are caused by the progressive loss of dopaminergic neurons in the substantia nigra pars compacta (SNpc). However, despite PDs first modern observation in 1817, little is understood about the causes and molecular mechanisms behind dopaminergic neuron loss. The relatively weak understanding of pathological mechanisms has hindered the development of treatments to slow or halt the progression of PD. However, recently, mounting evidence from post-mortem, imaging, and retrospective studies suggest an important role …

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The Interrelationships Among Obesity, Insulin Sensitivity, And Bone Phenotype In Pre-Pubertal Girls, Anna L. Newton Jan 2015

The Interrelationships Among Obesity, Insulin Sensitivity, And Bone Phenotype In Pre-Pubertal Girls, Anna L. Newton

All ETDs from UAB

Impaired insulin sensitivity as a consequence of childhood obesity has been implicated as a contributor to skeletal fragility. There is a need to understand the interrelationships among insulin sensitivity and skeletal parameters (i.e. cortical, trabecular, marrow) in obesity during the pubertal transition. Further, calorie restricted weight loss to stabilize these relationships warrants investigation as well. The goal of this project was to examine the relationships among body composition, skeletal parameters, and insulin sensitivity. The first aim was to evaluate the relationships among total body fat, bone mineral content (BMC) and femoral bone marrow adipose tissue (BMAT) during childhood and underlying …

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Lost (But Not Missing) At Work: Organizational Lostness As An Employee Response To Change, Lisa Jones Christensen, Scott C. Hammond Jan 2015

Lost (But Not Missing) At Work: Organizational Lostness As An Employee Response To Change, Lisa Jones Christensen, Scott C. Hammond

Faculty Publications

This article draws from the psychology of lost person behavior, established from wilderness search and rescue missions, to suggest that employees experience the condition of being lost within organizations. Data from wilderness searches, survivors, and organizational actors suggests that lessons from lost person behaviors apply in organizations. Reactions to being lost in an organization follow predictable patterns and include five specific stages: separation, isolation, deviation, deprivation, and realization. In defining the construct of organizational lostness and differentiating it from stress, coping, and resistance, we suggest an organizing framework to understand employee behaviors that would previously seem idiosyncratic. This article offers …

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The Effect Of Breakfast Protein Source On Postprandial Hunger And Glucose Response In Normal Weight And Overweight Young Women, Christina Crowder, Brianna I. Neumann, Jamie I. Baum Jan 2015

The Effect Of Breakfast Protein Source On Postprandial Hunger And Glucose Response In Normal Weight And Overweight Young Women, Christina Crowder, Brianna I. Neumann, Jamie I. Baum

Discovery, The Student Journal of Dale Bumpers College of Agricultural, Food and Life Sciences

Breakfast consumption has been linked to health benefits such as improved weight regulation and glucose control. Studies have shown higher protein breakfasts lead to a greater reduction in hunger compared to breakfasts higher in carbohydrates. However, few studies have examined the impact of higher protein breakfasts from differing protein sources. The objective of this study was to determine if protein quality (animal (AP) versus plant (PP) protein) influences postprandial appetite, food cravings, food intake and glucose response in participants consuming a high protein breakfast (~30% energy from protein). We hypothesized that AP would be more satiating than PP. Normal weight …

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Tau-Sh3 Interactions: Implications For Alzheimer's Disease, Jesse Nicholas Cochran Jan 2015

Tau-Sh3 Interactions: Implications For Alzheimer's Disease, Jesse Nicholas Cochran

All ETDs from UAB

Alzheimer’s disease (AD) is the most common neurodegenerative disease and with Americans’ increasing longevity it is becoming an epidemic. There are currently no effective treatments for this disorder. Abnormalities of tau track more closely with cognitive decline than the most studied therapeutic target in AD, amyloid-beta, but the optimal strategy for targeting tau has not yet been identified. Based on considerable preclinical data from AD models, we hypothesize that interactions between tau and SH3 domain–containing proteins are pathogenic in AD. Genetically reducing either tau or tau interactants has beneficial effects relevant to AD. Here, we describe a drug screen for …

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Behavioral And Developmental Abnormalities In Sult4a1 Deficient Zebrafish, Francis Crittenden Jan 2015

Behavioral And Developmental Abnormalities In Sult4a1 Deficient Zebrafish, Francis Crittenden

All ETDs from UAB

Since its identification in 2000, sulfotransferase (SULT) 4A1 has presented an enigma to the field of cytosolic SULT biology. SULT4A1 is exclusively expressed in neural tissue, is highly conserved, and has been identified in every vertebrate studied to date. Despite this singular level of conservation, no substrate or function for SULT4A1 has been identified. Previous studies demonstrated that SULT4A1 does not bind the obligate sulfate donor, 3’-phosphoadenosine-5’-phosphosulfate (PAPS), yet SULT4A1 is classified as a SULT superfamily member based on sequence and structural similarities to the other SULTs. In this study, RNA-seq was used to search for alterations in gene ex-pression …

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Mitragyna Speciosa: An Analytical Study, Jace Alan Daniels Jan 2015

Mitragyna Speciosa: An Analytical Study, Jace Alan Daniels

All ETDs from UAB

Legal highs are compounds that produce the same psychoactive effects as illicit compounds, but are not legally controlled under the Controlled Substances Act. While Kratom has been used for centuries by Thai laborers, it has recently been offered as a legal high by online markets and local head shops. Kratom is an indigenous plant to Southeast Asia, and the botanical name is Mitragyna speciosa. It is a mild stimulant, and the traditional use is to chew on leaves to overcome fatigue. Kratom is unique in that it is capable of producing both stimulant and sedative effects depending on the dose …

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Hepatocyte Clock And Alcohol-Dependent Disruption In Glycogen Metabolism, Uduak Sunday Udoh Jan 2015

Hepatocyte Clock And Alcohol-Dependent Disruption In Glycogen Metabolism, Uduak Sunday Udoh

All ETDs from UAB

Chronic alcohol consumption has been shown to significantly decrease hepatic glycogen, an important storage form of energy for the body and liver. Emerging studies indicate a link between metabolism and the molecular circadian clock. Previously, we have shown that chronic alcohol consumption disrupts the liver molecular clock mechanism. However, it is not known how this alteration impacts hepatic energy (e.g., glycogen) metabolism and contributes to alcohol hepatotoxicity. This dissertation investigates the impact chronic alcohol consumption has on time-of-day-dependent oscillations of various aspects of liver glycogen metabolism, and the importance of the liver circadian clock in these metabolic alterations. Chapter 1: …

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A Novel Role For Usp14 In Regulating Non-Proteolytic Ubiquitin Signaling, Jada Hallengren Vaden Jan 2015

A Novel Role For Usp14 In Regulating Non-Proteolytic Ubiquitin Signaling, Jada Hallengren Vaden

All ETDs from UAB

Loss of the deubiquitinating enzyme (DUB) USP14 in the ataxia (axJ) mice leads to altered neuromuscular junction (NMJ) structure, reduced synaptic transmission at the NMJ, and decreased mobility. However, the types of processes that USP14 regulates in the nervous system remain unclear. Because association with the proteasome stimulates USP14's ubiquitin hydrolase activity, it is thought to act primarily on proteasomal substrates. Therefore, one way for USP14 to support nervous system function is by modulating protein turnover. While a number of studies done in yeast and immortalized cell lines demonstrate that loss or inhibition of USP14 alters proteasome function, there is …

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The Effects Of The Initially Transcribed Sequence On Reiterative Transcription In Escherichia Coli, Jeffery Michael Vahrenkamp Jan 2015

The Effects Of The Initially Transcribed Sequence On Reiterative Transcription In Escherichia Coli, Jeffery Michael Vahrenkamp

All ETDs from UAB

Transcription, the synthesis of a ribonucleic acid transcript using a nucleic acid template, is the first step in gene expression for all life. In most organisms, high fidelity transcription is achieved through the formation of an RNA:DNA hybrid which allows the RNA polymerase to maintain the correct register. Slippage, which would lead to improper base pairing, is prevented by the heterogeneous sequence of the DNA template. However, when homogenous tracts of bases are present in the template, slippage can occur, allowing a single base in the template to encode multiple bases in the transcript in a process called reiterative transcription. …

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Aping Nobility: Reinterpreting The Mma "Monkey Cup", Ruoxin Wang Jan 2015

Aping Nobility: Reinterpreting The Mma "Monkey Cup", Ruoxin Wang

All ETDs from UAB

The “Monkey Cup” in the collection of the Metropolitan Museum of Art (MMA) exhibits a unique rendition of the monkeys robbing the sleeping peddler theme. Generally believed to have been created in the second quarter of the fifteenth century in Burgundian territories, the exact origin of the beaker is not known. Based on visual evidence and the socio-historical context, I propose that the “Monkey Cup” was created in the first quarter of the fifteenth century, and the attribution should be broadened to the greater circle of the Valois courts. In this thesis, I offer a new contextualized reading of the …

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Characterizing The Nuclear Import And Functions Of Cystin, The Ciliary Protein Disrupted In The Cpk Mouse Model Of Recessive Polycystic Kidney Disease, Jacob Asher Watts Jan 2015

Characterizing The Nuclear Import And Functions Of Cystin, The Ciliary Protein Disrupted In The Cpk Mouse Model Of Recessive Polycystic Kidney Disease, Jacob Asher Watts

All ETDs from UAB

Autosomal recessive polycystic kidney disease (ARPKD; MIM 263200) is a ma-jor cause of pediatric morbidity and mortality. Typically, orthologous animal models are the mainstay for pathogenic studies of human diseases. However, gene-targeting of Pkhd1, the mouse ortholog of the ARPKD gene, results in mutants with little or no kidney disease. In contrast, disruption of the non-orthologous gene, Cys1, in the cpk mouse model closely phenocopies human ARPKD. We speculate that this phenotypic similarity suggests that the Pkhd1 and Cys1 genes encode proteins (FPC and cystin, respectively) that share, at least in part, common molecular pathways. Our laboratory, as well as …

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Bioavailability Of Dietary Oxalate, Mary Catherine Robertson Jan 2015

Bioavailability Of Dietary Oxalate, Mary Catherine Robertson

All ETDs from UAB

Urolithiasis, or kidney stone disease, is a costly and painful health problem affecting about 8.8% of Americans with prevalence on the rise. Calcium oxalate stones account for about 80% of all stones. Increased urinary excretion of calcium and oxalate is a risk factor and central feature of such stones; dietary oxalate contributes up to 50% of urinary oxalate. The purpose of our research is to determine if physical manipulation such as chewing or blending prior to ingestion may render some oxalate more accessible for absorption in spinach, a high-oxalate food. In this crossover, controlled trial we enrolled six healthy, non-stone …

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The Mechanism Of Small Molecule Viral Fusion Inhibitors, Michael Joseph Rowse Jan 2015

The Mechanism Of Small Molecule Viral Fusion Inhibitors, Michael Joseph Rowse

All ETDs from UAB

All negative stranded RNA viruses (NSRV) have genomes encapsidated by oligomerized nucleoprotein (N). The N-RNA complex acts as the template for both transcription and replication. The crystal structure of the N protein from the model NSRV vesicular stomatitis virus (VSV) established the structural basis for the oligomerization of N-protein and the encapsidation of RNA. To determine how the structure of N protein changes in response to specific sequences of RNA, we developed a strategy to digest the random RNA encapsidated in the recombinant N-protein and reencapsidated specific RNA sequences. Poly-rA, poly-rC, poly-rU, and poly-rG sequences were encapsidated and co-crystallized with …

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The Unfolded Protein Response And Calcium Dysregulation In Autosomal Dominant Retinitis Pigmentosa Animal Models., Vishal Madhukar Shinde Jan 2015

The Unfolded Protein Response And Calcium Dysregulation In Autosomal Dominant Retinitis Pigmentosa Animal Models., Vishal Madhukar Shinde

All ETDs from UAB

The photoreceptor cell death in autosomal dominant retinitis pigmentosa (ADRP) is associated with molecular changes that occur due to mutations in a specific gene. S334ter RHO and P23H RHO are two ADRP rat models expressing mutant rhodopsin. The unfolded protein response (UPR) is a cellular stress response involved in the pathophysiology of several retinal disorders including P23H RHO rats. Considering our previous findings, we started our investigation by examining the status of UPR in S334ter RHO rats. As UPR tightly regulates several signaling pathways, we further studied whether UPR activation in S334ter and P23H RHO retina is accompanied by the …

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The Multifactorial Roles Of The Cytokines Il-21 And Il-22 In Mediating Host Defense Against Enteropathogenic Infection, Daniel James Silberger Jan 2015

The Multifactorial Roles Of The Cytokines Il-21 And Il-22 In Mediating Host Defense Against Enteropathogenic Infection, Daniel James Silberger

All ETDs from UAB

Enteropathogenic strains of Escherichia coli are a major public health concern, causing diarrhea and mortality particularly among infants and children in developing countries. Citrobacter rodentium is a murine intestinal pathogen that models pathogenic E. coli infection. Both innate and adaptive immune cells contribute to the clearance of C. rodentium. In particular, B cells and CD4+ T cells but not CD8+ T cells are required for protection during a primary infection with C. rodentium. In addition, T cell-dependent antibody responses are required for clearance. Th17 cells are a major CD4+ T cell population that accumulates in the large intestine during C. …

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Compatibility Of The Parasitoid Spalangia Endius (Hymenoptera: Pteromalidae) And Insecticides Against Musca Domestica (Diptera: Muscidae) As Evaluated By A New Index., Edwin R. Burgess, Bethia H. King Jan 2015

Compatibility Of The Parasitoid Spalangia Endius (Hymenoptera: Pteromalidae) And Insecticides Against Musca Domestica (Diptera: Muscidae) As Evaluated By A New Index., Edwin R. Burgess, Bethia H. King

Faculty Articles, Papers, and Other Scholarship

Various insecticides for the control of the house fly Musca domestica L. were tested for compatibility with a biological control agent, the pupal parasitoid Spalangia endius Walker. Bioassays used the mode in which each organism was expected to be harmed by the insecticides, a surface contact bioassay for S. endius and a feeding bioassay for M. domestica. A Pesticide Compatibility Index (PCI) was created that allows comparison of LC50 values when the mode of exposure to a pesticide differs. First LC50 values were converted into units of prescribed dosages (LPR = LC50-to-prescribed dosage ratio). This study used dosages from labels …

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Comparison Of Gut Microbiomes In Laboratory Cultured Sea Urchins Revealing Selective Attributes Of Microbial Composition Based Upon Their Feed And Surroundings, Joseph Antoine Hakim Jan 2015

Comparison Of Gut Microbiomes In Laboratory Cultured Sea Urchins Revealing Selective Attributes Of Microbial Composition Based Upon Their Feed And Surroundings, Joseph Antoine Hakim

All ETDs from UAB

Bacteria residing in the gastrointestinal tract play important roles in digestive physiology and host health. The advent of NextGen sequencing and bioinformatics has made it possible to establish taxonomic profiles with highest coverage, and map these microbes in the gut ecosystem. Although extensively studied in the context of human health, understanding the microbial profiles associated with other organisms will elucidate the roles of the microbial inhabitants to their respective hosts and environment. The microbes of the sea urchin gut have been linked to digestion, processing, and extraction of nutrients from ingesta while within the gut, and have also been implicated …

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Obesity Weighs Down Memory: Emerging Insights Into The Epigentic Basis Of Obesity-Induced Memory Impairment In Adult Mice, Frankie Darryn Heyward Jan 2015

Obesity Weighs Down Memory: Emerging Insights Into The Epigentic Basis Of Obesity-Induced Memory Impairment In Adult Mice, Frankie Darryn Heyward

All ETDs from UAB

A preponderance of evidence has established that obesity contributes to memory impairments in mid-age adults. Empirical evidence has revealed that diet-induced obesity contributes to memory impairments in adult rodents. Precisely how obesity disrupts memory remains an open question. Bourgeoning data indicate that molecular epigenetic mechanisms mediate the changes in gene transcription that are necessary for hippocampus-dependent memory consolidation. Epigenetic mechanisms, such as DNA methylation, stably regulate gene expression without affecting the DNA sequence. Moreover, DNA methylation of memory-related genes with in the hippocampus is indispensible for memory formation. There is recent evidence of obesity-induced aberrantions in DNA methylation both peripherally …

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Metabolic And Oxidative Regulation Of Neuronal Autophagy And Survival, Matthew Dodson Jan 2015

Metabolic And Oxidative Regulation Of Neuronal Autophagy And Survival, Matthew Dodson

All ETDs from UAB

Neurodegenerative diseases, such as Parkinson's disease, Alzheimer's disease and Huntington's disease are all characterized by metabolic dysfunction, increased oxidative damage to proteins and organelles, formation of proteinaceous inclusions, decreased autophagic and proteasomal function, and eventual neuronal and glial cell death. While our understanding of the mechanisms that underlie many of these pathologies is constantly growing, their exact cause, onset, interplay and progression still remain unclear. The gap between the description of disease pathologies and understanding the fundamental mechanisms of disease pathogenesis, progression and potential therapeutics to mitigate disease progression is still large. Based on the observation that altered glucose utilization, …

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The Characterization Of Human Cytosolic Sulfotransferase 1a1: Interactions With 17Α-Ethinylestradiol, Katie Jo Glowacki Jan 2015

The Characterization Of Human Cytosolic Sulfotransferase 1a1: Interactions With 17Α-Ethinylestradiol, Katie Jo Glowacki

All ETDs from UAB

Human cytosolic sulfotransferases (SULTs) are a family of Phase II conjugating enzymes that facilitate the transfer of a sulfonate moiety from 3’phosphoadenosine 5’phosphosulfate (PAPS) to hydroxyl or amine groups of acceptor substrates. SULT1A1, located in many tissues throughout the human body including the liver, is important in the metabolism of many endogenous, exogenous, xenobiotic, and drug compounds. The majority of substrates for SULT1A1 are small neutral phenols including 1-naphthol and acetaminophen; however, SULT1A1 sulfates larger compounds including 17β-estradiol (E2) and raloxifene. SULT1A1 conjugates E2 with a Km of 2.3 µM and the structure of E2 is almost identical to the …

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Probing Astrocytes With Carbon Nanotubes And Assessing Their Effects On Astrocytic Structural And Functional Properties, Manoj K. Gottipati Jan 2015

Probing Astrocytes With Carbon Nanotubes And Assessing Their Effects On Astrocytic Structural And Functional Properties, Manoj K. Gottipati

All ETDs from UAB

Single-walled carbon nanotubes, chemically-functionalized with polyethylene glycol (SWCNT-PEG) have been shown to modulate the morphology and proliferation characteristics of astrocytes in culture, when applied to the cells as colloidal solutes or as films upon which the cells can attach and grow. These changes were associated with a change in the immunoreactivity of the astrocyte-specific protein, glial fibrillary acidic protein (GFAP); the solutes and films caused an increase and a decrease in GFAP levels, respectively. To assess if these morpho-functional changes induced by the SWCNT-PEG modalities are dependent on GFAP or if the changes in GFAP levels are independent events, I …

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Emotion Regulation And Neuropathic Pain Following Spinal Cord Injury (Sci): Influence Of Emotional Processes On The Efficacy Of A Novel Treatment Paradigm For Sci-Related Pain, Juliette Galindo Jan 2015

Emotion Regulation And Neuropathic Pain Following Spinal Cord Injury (Sci): Influence Of Emotional Processes On The Efficacy Of A Novel Treatment Paradigm For Sci-Related Pain, Juliette Galindo

All ETDs from UAB

While spinal cord injury (SCI) is a relatively rare in the general population, it has significant implications on functionality, independence, and quality of life for individuals who are affected by it. Common sequelae of SCI include sensorimotor dysfunction and pain symptoms that are often severe. More specifically, approximately 33% of individuals with SCI experience severe, intractable neuropathic pain. Additionally, treatments for neuropathic pain have variable efficacy and/or many side effects. While SCI-related neuropathic pain is thought to be related to cortical reorganization and nerve damage, there may be psychological factors that contribute to increased pain severity and variable treatment response. …

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Bioenergetics As A Biomarker Of Health And Disease, Philip Kramer Jan 2015

Bioenergetics As A Biomarker Of Health And Disease, Philip Kramer

All ETDs from UAB

The increasing prevalence of metabolic syndrome, diabetes, atherosclerosis, and many other diseases only recently associated with aberrant metabolism, have led to a de-mand for clinical assays to determine a patient’s mitochondrial health. With the rapidly growing interest in personalized medicine, such an assay would ideally be able to capture the metabolic changes associated with oxidative stress, inflammation, and therapy of a patient in a swift and non-invasive manner. Short of tissue biopsies, this burgeoning field of Translational Bioenergetics has had minimal success in obtaining sufficient human cells and the means to assess them both accurately and swiftly. The purpose of …

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The Biological And Conservational Implications Of Hatchling Biology In The Kemp's Ridley (Lepidochelys Kempii) Sea Turtle, Amy Nicole Bonka Jan 2015

The Biological And Conservational Implications Of Hatchling Biology In The Kemp's Ridley (Lepidochelys Kempii) Sea Turtle, Amy Nicole Bonka

All ETDs from UAB

The Kemp’s ridley sea turtle is currently listed as critically endangered, and has a very limited range, often found along the Atlantic coast though primarily inhabiting the Gulf of Mexico, with the majority of all nesting occurring near Rancho Nuevo, Mexico. Historically, large numbers of turtles have been reported to nest at Rancho Nuevo; though numbers dropped due to egg take and by-catch in the fishing and shrimping industries. Extensive conservation efforts over the last several decades significantly increased the number of nests; however the recovery status of the Kemp’s ridley is still in question, and the continued research and …

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Transferring Virtual Reality Training To Real World Settings In Individuals With Low Vision And Dual-Sensory Impairments, Ellen Lambert Bowman Jan 2015

Transferring Virtual Reality Training To Real World Settings In Individuals With Low Vision And Dual-Sensory Impairments, Ellen Lambert Bowman

All ETDs from UAB

TRANSFERRING VIRTUAL REALITY TRAINING TO REAL WORLD SETTINGS IN INDIVIDUALS WITH LOW VISION AND DUAL-SENSORY IMPAIRMENTS ELLEN LAMBERT BOWMAN VISION SCIENCE GRADUATE PROGRAM ABSTRACT The goal of this study was to determine if individuals with low vision could learn useful visual skills in Virtual Reality and could transfer these skills to the real world. To achieve this goal, one set of Orientation & Mobility (O&M) skills, using the near lane parallel traffic surge to decide the safest timing to cross a signal controlled street, was selected. Twelve participants with vision too poor to use pedestrian signals were randomly assigned to …

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