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2015

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Special Speciation, Lyn L. Countryman, Jill D. Maroo Jan 2015

Special Speciation, Lyn L. Countryman, Jill D. Maroo

Faculty Publications

Considerable anecdotal evidence indicates that some of the most difficult concepts that both high school and undergraduate elementary-education students struggle with are those surrounding evolutionary principles, especially speciation. It’s no wonder that entry-level biology students are confused, when biologists have multiple definitions of “species.” We developed this speciation activity to provide clarity and allow students a hands-on experience with a speciation model.

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Upper Elementary Students Creatively Learn Scientific Features Of Animal Skulls By Making Movable Books, Juile L. Klein, Phyllis Gray, Ksenia S. Zhbanova, Audrey C. Rule Jan 2015

Upper Elementary Students Creatively Learn Scientific Features Of Animal Skulls By Making Movable Books, Juile L. Klein, Phyllis Gray, Ksenia S. Zhbanova, Audrey C. Rule

Curriculum & Instruction Faculty Publications

Arts integration in science has benefits of increasing student engagement and understanding. Lessons focusing on form and function of animal skulls provide an effective example of how handicrafts integrated with science instruction motivate students and support learning. The study involved students ages 9-12 during a week-long summer day camp. Students applied animal skull concepts of eye positions of predators and prey, relative eye sizes of nocturnal animals compared to tunnel-dwellers, shapes and functions of different types of teeth, and terminology and functions of different bones, openings, and structures of animal skulls in making moveable book pages. These pages featured pop-up …

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Feasibility Of Using Biofuel By-Products As A Sustainable Nutritional Resource For Aquaculture Production Of Litopenaeus Vannamei, Erik David Demicco Jan 2015

Feasibility Of Using Biofuel By-Products As A Sustainable Nutritional Resource For Aquaculture Production Of Litopenaeus Vannamei, Erik David Demicco

HCNSO Student Theses and Dissertations

Many different algal species can provide an acceptable protein ingredient, with good digestibility, for shrimp feeds. Compared to fish meal, similar protein, carbohydrate, and lipid levels can be found in select algal species. Traditional shrimp diets in aquaculture rely on fish meal and fish oil from pelagic fish fisheries. A reduction or elimination of these ingredients would reduce the dependency of shrimp aquaculture on offshore fisheries and increase economic competiveness. Biofuel production produces algal by-products of potential use to aquaculturists that might reduce or eliminate the need for fisheries products in shrimp feed. Established uses for by-products from biofuel production …

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Hallowed Be Thy Fall, Kristina Smeriglio Jan 2015

Hallowed Be Thy Fall, Kristina Smeriglio

Department of Writing and Communication Theses

All Priella wanted was to find love. She roamed the fields of the Garden of Earthly Delights, day by day, in the hopes of finally attaining it. But, it wasn't that simple. In the midst of an existential crisis, unable to understand her difficulty in relating to others and achieving happiness, Priella meets the Archangel Michael who offers her a chance at salvation. Venturing into the unknown, Priella is forced to face the distorted ways of thinking that kept her hostage.

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Carnival Of Creeps, Richard Rodriguez Jan 2015

Carnival Of Creeps, Richard Rodriguez

Department of Writing and Communication Theses

No abstract provided.

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Conservative Collision Course: The Tension Between Conservative Corporate Law Theory And Citizens United, Leo E. Strine Jr., Nicholas Walter Jan 2015

Conservative Collision Course: The Tension Between Conservative Corporate Law Theory And Citizens United, Leo E. Strine Jr., Nicholas Walter

Cornell Law Review

No abstract provided.

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Constitutional Law And The Law Of Evidence, Brandon L. Garrett Jan 2015

Constitutional Law And The Law Of Evidence, Brandon L. Garrett

Cornell Law Review

No abstract provided.

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Servsafe® Exam: Student's Memory Retention Two Years Later, Laura E. Tincher Jan 2015

Servsafe® Exam: Student's Memory Retention Two Years Later, Laura E. Tincher

Theses and Dissertations--Nutrition and Food Systems

This study analyzed the memory retention of University of Kentucky Dietetic and Hospitality students as it relates to food safety and sanitation knowledge originally presented on the ServSafe® certification exam. Dietetic and hospitality students take the ServSafe® certification course during the sophomore year of their degree program, but they are responsible for the sanitation and food safety information throughout their entire program of undergraduate study. The final sample consisted of 25 participants, with 84% (n=21) in the Dietetics program and 16% (n=4) in the Hospitality, Management and Tourism program. The mean difference in total score, domain one, domain two, domain …

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Four Narratives Of Cross-Dressing In Twentieth-Century Art : Marcel Duchamp, Claude Cahun, Eleanor Antin, And Diane Torr, Chrisoula Gardiakos Jan 2015

Four Narratives Of Cross-Dressing In Twentieth-Century Art : Marcel Duchamp, Claude Cahun, Eleanor Antin, And Diane Torr, Chrisoula Gardiakos

Graduate Research Theses & Dissertations

This essay looks at cross-dressing as a trope in fine art across the twentieth century. The respective contemporaneous discourse that was taking place informed artists Marcel Duchamp, Claude Cahun, Eleanor Antin and Diane Torr's art practice. These separate artistic engagements are referred to as narratives. Duchamp was engaged with the Victorian era's notion of allegorical alchemy, which was widely accepted as an artistic endeavor by many modern artists, and its connection to androgyny. Cahun was engaged in the medical models of homosexuality, which was synonymous with cross-dressing during the early part of the twentieth century and questioned rigid gender roles. …

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A Case For Weakening Patent Rights, Lucas S. Osborn, Joshua M. Pearce, Amberlee Haselhuhn Jan 2015

A Case For Weakening Patent Rights, Lucas S. Osborn, Joshua M. Pearce, Amberlee Haselhuhn

Scholarly Works

This Article contributes to the patent debate by observing that new and emerging technologies are radically altering the relative costs and benefits of the patent system. Although analysts cannot measure the patent system's numerous absolute costs and benefits, this Article demonstrates that new and emerging technologies are significantly reducing the research, development, and commercialization costs ("innovation costs") that are used by adherents to the incentive and prospect theories to justify the patent system's existence. All things being equal, if significantly, the relative need for the patent system has decreased and will continue to decrease. Thus, this Article argues that patents …

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Ce 611 Syllabus: Lifespan Development, Mary Fawcett Jan 2015

Ce 611 Syllabus: Lifespan Development, Mary Fawcett

Counselor Education Syllabi

The purpose of this course is to provide an overview of perspectives on the normal development of children, adolescents and adults.

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Whose Urban Forest? The Political Ecology Of Foraging Urban Nontimber Forest Products, Patrick T. Hurley, Marla R. Emery, Rebecca J. Mclain, Melissa R. Poe, Brain Grabbatin, Cari L. Goetcheus Jan 2015

Whose Urban Forest? The Political Ecology Of Foraging Urban Nontimber Forest Products, Patrick T. Hurley, Marla R. Emery, Rebecca J. Mclain, Melissa R. Poe, Brain Grabbatin, Cari L. Goetcheus

Institute for Sustainable Solutions Publications and Presentations

Drawing on case studies of foraging in Philadelphia, Pennsylvania and Mt. Pleasant, South Carolina, we point to foraging landscapes and practices within diverse urban forest spaces. We examine these spaces in relation to U.S. conservation and development processes and the effects of management and governance on species valued by foragers. These case studies reveal the everyday landscapes of urban foraging and suggest that ideas about what constitutes the suite of appropriate human-environment interactions in the sustainable city are contested and accommodated in diverse ways.

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Contributors, Criterion: A Journal For Literary Criticism Jan 2015

Contributors, Criterion: A Journal For Literary Criticism

Criterion: A Journal of Literary Criticism

No abstract provided.

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Impacts Of Climate, Geography And White-Nose Syndrome Mortality On The Population Genetic Structure And Variation Of Myotis Lucifugus In The Eastern United States, Shannon Marie Dodge Morgan Jan 2015

Impacts Of Climate, Geography And White-Nose Syndrome Mortality On The Population Genetic Structure And Variation Of Myotis Lucifugus In The Eastern United States, Shannon Marie Dodge Morgan

Legacy Theses & Dissertations (2009 - 2024)

A myriad of biotic and abiotic factors contribute to the fluctuations in geographic range and size of animal populations. In the Nearctic, bat species have experienced drastic historic changes in available habitat due to Pleistocene glaciations, and are recently imperiled by the introduction of a novel fungal pathogen, Pseudogymnoascus destructans within the last decade. Myotis lucifugus in particular has lost 90-95% of the population in the eastern US due to the fungal disease White-Nose Syndrome (WNS). A population decline of this magnitude will likely result in a loss of allelic diversity as a result of a genetic bottleneck. My study …

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Understanding Transcriptional Enhancement In Monoclonal Antibody-Producing Chinese Hamster Ovary Cells, Sarah E. Nicoletti Jan 2015

Understanding Transcriptional Enhancement In Monoclonal Antibody-Producing Chinese Hamster Ovary Cells, Sarah E. Nicoletti

Legacy Theses & Dissertations (2009 - 2024)

With the demand for monoclonal antibody (mAB) therapeutics continually increasing, the need to better understand what makes a high productivity clone has gained substantial interest. Monoclonal antibody producing Chinese hamster ovary (CHO) cells with different productivities were provided by a biopharmaceutical company for investigation. Gene copy numbers, mRNA levels, and mAb productivities were previously determined for two low producing clones and their amplified progeny. These results showed an increase in mRNA copy number in amplified clones, which correlated to the observed increases in specific productivity of these clones. The presence of multiple copies of mRNA per one copy of DNA …

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Human Feeding Biomechanics : Intraspecific Variation And Evolution, Justin Ledogar Jan 2015

Human Feeding Biomechanics : Intraspecific Variation And Evolution, Justin Ledogar

Legacy Theses & Dissertations (2009 - 2024)

This study examines feeding biomechanics in modern human crania and those of extinct early members of the human lineage in order to better understand the selective pressures that influenced human craniofacial evolution. Specifically, this study uses finite element analysis to examine: 1) human feeding performance, in terms bite force production and craniofacial strength; 2) intraspecific variation in human feeding biomechanics; 3) feeding biomechanics in fossil hominins, including Australopithecus sediba and Homo habilis, species that are potentially at the root of modern human lineage, and 4) the functional role of purported facial buttresses.

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Antibiotics, The Microbiome, And Immunity : A Case Study In Bangladesh, Carmen Fagnani Jan 2015

Antibiotics, The Microbiome, And Immunity : A Case Study In Bangladesh, Carmen Fagnani

Legacy Theses & Dissertations (2009 - 2024)

The purpose of this study was to establish a theoretical impact of antibiotic misuse on the microbiome and its effects on immunity. Recent studies indicate the importance of a microbiome on the immune system. Both the leptin signaling pathways and CD4T cell production are influenced by the microbiome (Mazmanian, et al. 2005). The use of antibiotics has been associated with dysbiosis, a microbial imbalance in the digestive tract. The immune system is limited when the microbiome is dysbiotic.

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Characterization Of R-Plasmid Dependent Single-Stranded Rna Phages : Interactions Of Phage Hgal1 With Five Enterobacteriaceae Species, Sherin Kannoly Jan 2015

Characterization Of R-Plasmid Dependent Single-Stranded Rna Phages : Interactions Of Phage Hgal1 With Five Enterobacteriaceae Species, Sherin Kannoly

Legacy Theses & Dissertations (2009 - 2024)

Viruses in general have a narrow host range, usually infecting a single or very closely related host species. Recently, emerging diseases in human populations have been increasingly attributed to host range expansion in animal viruses. Many studies have investigated host range expansion in model systems involving animal viruses and potential hosts. My study describes the development of a model system that uses a single-stranded RNA (ssRNA) phage and five Enterobacteriaceae species. The study involved: I) Characterization of two ssRNA phages, Hgal1 and C-1, and assessing their abilities to infect multiple hosts, II) Developing and characterizing a model system involving an …

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Francisella Tularensis Catalase Restricts Immune Function By Impairing Trpm2 Channel Activity, Nicole Lynn Flaherty Jan 2015

Francisella Tularensis Catalase Restricts Immune Function By Impairing Trpm2 Channel Activity, Nicole Lynn Flaherty

Legacy Theses & Dissertations (2009 - 2024)

As an innate defense mechanism, macrophages produce reactive species that weaken pathogens and serve as secondary messengers to modify signaling responses involved in immune function. The gram-negative bacterium F. tularensis utilizes its antioxidant armature to limit the host immune response but the mechanism behind this suppression has not been defined. Here we establish that F. tularensis limits Ca2+ entry thereby limiting actin reorganization and IL-6 production in a redox-dependent fashion. Wild-type (LVS) or catalase deficient F. tularensis (∆katG) show distinct profiles in their H2O2 scavenging capacity, 1 pM/sec and 0.015 pM/sec, respectively. Murine alveolar macrophages infected with ∆katG display distinct …

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Gendered Patriots And Post-Revolutionary Ladies : Girl Guiding And Twentieth Century Mexican Girlhood, Maryann Kelly Jan 2015

Gendered Patriots And Post-Revolutionary Ladies : Girl Guiding And Twentieth Century Mexican Girlhood, Maryann Kelly

Legacy Theses & Dissertations (2009 - 2024)

Through the lens of the Guías de México (Girl Guides of Mexico), Gendered Patriots and Postrevolutionary Ladies examines Girl Guide efforts to advance international cooperation and peace by promoting international friendship among the world’s youth between 1919 and 1980. From its birth as a branch of the British Girl Guide Movement, Mexican Guides participated in the World Association of Girl Guides and Girl Scout’s (WAGGGS) international conferences, encampments, and global initiatives. During the first half of the twentieth century Western European and United States members established WAGGGS global agenda for social reform and the advancement of women and youth. At …

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Developing A Weibull Model Extension To Estimate Cancer Latency Times, Diana L. Nadler Jan 2015

Developing A Weibull Model Extension To Estimate Cancer Latency Times, Diana L. Nadler

Legacy Theses & Dissertations (2009 - 2024)

More than one-third of all Americans will be diagnosed with cancer sometime in their lives. Though their illness may be invisible now, it presents a great, and largely unexamined, opportunity to find and treat their cancers early. Early detection represents one of the most promising approaches to reduce the growing cancer burden by identifying cancer while it is localized and curable, preventing not only mortality, but also reducing morbidity and costs.

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Role Of Antibody Isotypes In Providing Passive Protection Against Ricin Toxin, Ipneet Kaur Dhaliwal Jan 2015

Role Of Antibody Isotypes In Providing Passive Protection Against Ricin Toxin, Ipneet Kaur Dhaliwal

Legacy Theses & Dissertations (2009 - 2024)

Ricin toxin is a glycoprotein produced by the castor bean plant, Ricinus communis. Ricin is an extraordinarily potent inducer of cell death and inflammation, especially following inhalation. The toxin’s enzymatic subunit (RTA) is transported via retrograde transport into the cytoplasm of mammalian cells by the toxin’s B subunit (RTB). Once in the cytoplasm, RTA inactivates ribosomes through cleavage of ribosomal RNA. In this study, I characterized a ricin-specific monoclonal IgA antibody (mAb) known as 23D7. I confirmed that 23D7 reacts with RTA and is effective at neutralizing ricin in a Vero cell cytotoxicity assay in vitro. To localize the epitope …

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Eighth Grade Girls' Knowledge Building With Narrative Texts, Julie Smit Jan 2015

Eighth Grade Girls' Knowledge Building With Narrative Texts, Julie Smit

Legacy Theses & Dissertations (2009 - 2024)

This study focused on the knowledge building work of eighth grade female avid readers who were invited to discuss their experiences with reading narrative fiction. The study examined the kinds of knowledge these students drew on and constructed and the processes they used to do so. The following research questions were asked: What kinds of experiences do eighth grade female avid readers have with narrative works? What kinds of knowledge were being built? How do these avid readers arrive at new understandings? How do these eighth grade female avid readers transform their individual and collective understandings?

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Government-Nonprofit Relationships And The Management Process Of Social Welfare Service Contracting In Korea, Ji Sun Kang Jan 2015

Government-Nonprofit Relationships And The Management Process Of Social Welfare Service Contracting In Korea, Ji Sun Kang

Legacy Theses & Dissertations (2009 - 2024)

This dissertation is an exploratory analysis of a government policy tool− contracting out social welfare services with nonprofit organizations− that aims to identify how contracting relationships between public and nonprofit managers influence the contract management process. The theoretical framework draws on the government-nonprofit relationship literature, especially studies that rely on resource dependence theory and agency theory. Using data gathered from interviews conducted with public officials in district governments and workers in social welfare centers in Korea, this dissertation examines the contract management process, particularly negotiation, monitoring, and evaluation through five critical dimensions of the contracting relationship: power, resources, communication, information …

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Coherent Scattering Imaging Monte Carlo Simulation, Laila Hassan Jan 2015

Coherent Scattering Imaging Monte Carlo Simulation, Laila Hassan

Legacy Theses & Dissertations (2009 - 2024)

Conventional mammography has poor contrast between healthy and cancerous tissues due to the small difference in attenuation properties. Coherent scatter potentially provides more information because interference of coherently scattered radiation depends on the average intermolecular spacing, and can be used to characterize tissue types. However, typical coherent scatter analysis techniques are not compatible with rapid low dose screening techniques. Coherent scatter slot scan imaging is a novel imaging technique which provides new information with higher contrast. In this work a simulation of coherent scatter was performed for slot scan imaging to assess its performance and provide system optimization. In coherent …

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Evolution Of Viral Host Recognition Through Multiple Pathways, Sara Stark Jan 2015

Evolution Of Viral Host Recognition Through Multiple Pathways, Sara Stark

Legacy Theses & Dissertations (2009 - 2024)

Most viruses are specialists and have a narrow host range, infecting only a single species or host strain. However, many of the viruses currently responsible for causing emerging infectious diseases are generalists and able to infect a wider host range. Viruses that are able to infect multiple hosts are more likely to continue expanding their host range and infecting additional species. The ability to infect a novel host is a complex process. The first step required to acquire the ability to infect a novel host is host recognition; the host recognition binding protein on the virus must be able to …

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Mass Spectrometry-Based Rnomics : Global Surveys Of Ribonucleotide Modifications As Possible Indicators Of Cell Identity, Epigenetic, Metabolic And Pathological State, Rebecca Erin Rose Jan 2015

Mass Spectrometry-Based Rnomics : Global Surveys Of Ribonucleotide Modifications As Possible Indicators Of Cell Identity, Epigenetic, Metabolic And Pathological State, Rebecca Erin Rose

Legacy Theses & Dissertations (2009 - 2024)

Discovery of the regulatory roles of non-protein coding RNAs (ncRNAs), once considered “junk” or “transcriptional noise”, has prompted a reassessment of the significance of the multifaceted activities of RNA in cellular response, which can result in cell transformation and diseased states. This reassessment, however, can only be accomplished if techniques are developed to capture, characterize and quantify the more than 100 covalent post-transcriptional modifications (PTMs) that adorn natural RNAs. Undoubtedly, the creation of high-throughput platforms such as next-generation sequencing and RNA-seq have provided unparalleled accuracy and sensitivity, however, they rely on strand amplification procedures that are blind to the known …

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Plato And The Sophists : Eristic Practice, Cognition, And Perception, Kevin W. Olbrys Jan 2015

Plato And The Sophists : Eristic Practice, Cognition, And Perception, Kevin W. Olbrys

Legacy Theses & Dissertations (2009 - 2024)

This dissertation traces metaphysical, epistemological and cognitive developments in Plato’s canon from his earlier Euthydemus and Charmides to his great work on epistemology, the Theaetetus. I argue that Plato’s confrontation with eristic (the methodology of his philosophical predecessors, the sophists) presents him with a serious epistemological challenge that can only be met through the development of a philosophical theory of cognition and perception. I also argue that the Theaetetus only appears to be an aporetic dialogue; read in the context of Plato's earlier work, it actually offers a series of refutations aimed at the theoretical assumptions that underpin the practice …

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Creation Of A 3d Construct To Aid Cell Migration And Promote Cell Capture, Joseph Michael Sanders Jan 2015

Creation Of A 3d Construct To Aid Cell Migration And Promote Cell Capture, Joseph Michael Sanders

Legacy Theses & Dissertations (2009 - 2024)

Most cancer-related deaths are attributed to metastasis. The tumor microenvironment is a complex environment which is not fully understood. The Nano Intravital Device (NANIVID) is a versatile, biocompatible device that allows for the manipulation of the tumor microenvironment in vitro and in vivo, providing a platform to study various aspects of tumor progression. The purpose of this study is to modify the NANIVID to resemble the tumor microenvironment in order to allow for a seamless transition from the in vivo environment into the engineered environment within the NANIVID. This engineered microenvironment will promote cell migration and cell capture. It has …

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Examining The Craniofacial Biomechanics Of Paranthropus Boisei, Amanda L. Smith Jan 2015

Examining The Craniofacial Biomechanics Of Paranthropus Boisei, Amanda L. Smith

Legacy Theses & Dissertations (2009 - 2024)

An engineering method, finite element analysis (FEA), was used to examine the craniofacial biomechanics of Paranthropus boisei. The craniofacial morphology of Paranthropus boisei exhibits a number of highly derived characteristics that have commonly been thought to be related to feeding. This series of studies includes an ex vivo strain gage study (validation of techniques), an assessment of the effects of intraspecific craniofacial shape variation in chimpanzees (Pan troglodytes), and an examination of the feeding biomechanics of Paranthropus boisei. Modeling experiments were also conducted to test mechanical hypotheses regarding the effects of specific derived craniofacial features on Paranthropus feeding function.

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