Digital Commons Network^™

Design And Evaluation Of A Primary / Secondary Pumping System For A Heat Pump Assisted Solar Thermal Loop, Kyle Gene Krockenberger

Open Access Theses

A heat pump assisted solar thermal system was designed, commissioned, tested and analyzed over a period of two years. The unique system uses solar energy whenever it is available, but switches to heat pump mode at night or whenever there is a lack of solar energy. The solar thermal energy is added by a variety of flat plat solar collectors and an evacuated tube heat pipe solar collector. The working medium in the entire system is a 50% mixture of propylene glycol and water for freeze protection. During the design and evaluation the primary / secondary pumping system was the …

Analyzing The Perceptions Of The General Public With Regard To Meat Production In The U.S.: A Spotlight On Pork Production And The Impacts Of The Fair Oaks Farms’ Pig Adventure, Ann Marie Cummins

Open Access Theses

Consumers have an increasing amount of information available to them while make purchasing decisions for livestock products. This information increasingly includes both production and product components. It is evident that along with this increasing amount of available information consumers also have an increased interest in farming practices associated with the rearing of livestock. Therefore, it is important to have an increased understanding in consumer’s perceptions and level of concern for production attributes, such as animal welfare, relative to product attributes such as taste and price. This analysis examines United States residents’ demographics, knowledge, sources of information, and perceptions on livestock …

Factors That Influence The Adoption Of Hermetic Storage, Evidence From Nepal, James Henry Flock

Open Access Theses

ABSTRACT

Morphological Plasticity Of Invasive Silver Carp In Divergent Midwestern Rivers, Katherine Flynn Touzinsky

Open Access Theses

In the past decade, silver carp (SC; Hypopthalmicthys molitrix) have incited a great quantity of scientific research because their establishment and success in the Midwestern U.S. has led to concerns that they could invade the Great Lakes Basin. These previous studies have identified phenotypic plasticity in SC behavior and spawning as they invade novel environments. Although divergent habitats have been shown to elicit morphological plasticity in multiple fish species, similar research has not been conducted for SC despite their observed plasticity in other traits. I examined SC collected from two hydrogeomorphically divergent rivers, the Illinois River (IR) and middle Wabash …

Can We Put Photobiology To Work? Using Light To Manipulate The Nutritional And Sensory Properties Of Greenhouse Tomatoes, Michael Dzakovich

Open Access Theses

While generally viewed within the context of plant growth and development, different qualities of light are also powerful elicitors of secondary metabolic pathways in plants that affect the nutritional value and flavor of edible tissues. Leveraging fundamental photobiology principles, our studies sought to use different qualities of supplemental light including ultraviolet-B (UV-B), UV-A, blue, red, and far-red as an environmental treatment to restore garden-grown flavor and nutritional attributes to greenhouse-grown tomatoes (Solanum lycopersicum); a commercially important crop that has a poor reputation compared to its garden-grown counterparts. To test our hypotheses, we used a battery of physicochemical analyses that included …

Investigating The Amino Acid Digestibility Of Alternative Protein Sources And Determining The Impact Of Dietary Fiber On Energy, Nitrogen, And Amino Acid Digestibility In Growing Pigs, Bradley M. Cotten

Open Access Theses

Three experiments were designed to quantify the nitrogen (N) and amino acid (AA) digestibility of various protein sources fed to growing pigs. The protein ingredients were sunflower meal, cottonseed meal, canola meal, camelina meal, egg albumen, casein, blood meal, plasma meal, potato protein concentrate, soy protein concentrate, soy protein isolate, and linseed meal, which were fed as the sole source of amino acids for the animals and were included in semi-purified, corn starch-based diets. A semi-purified, nitrogen-free diet (NFD) was used to estimate endogenous losses of AA. In each experiment, pigs were surgically fitted with a simple T-cannula at the …

In Vivo Analysis Of A Salt Bridge At The External Gate Of The Drosophila Melanogaster Serotonin Transporter In Response To Amphetamines, Timothy J. Beenen

Open Access Theses

Monoamine neurotransmitter transporters are membrane proteins responsible for the clearing of biogenic amines from a synapse. These transporters are targets for many important pharmaceuticals including antidepressants, as well as psychostimulant drugs such as cocaine and amphetamines. Amphetamines are believed to elicit their psychostimulant activity primarily by inducing a reversal of the transport cycle and increasing neurotransmitter release into the synapse, though the mechanism of this activity is incompletely understood. Previous in vitro research has suggested functional significance of a conserved salt bridge in the serotonin transporter (SERT) in amphetamine-induced 5-HT efflux. This salt bridge is disrupted in the Drosophila melanogaster …

Identification, Description, And Activity Of Proteins In The Tergal Glands Of The German Cockroach, Blattella Germanica (L.), Aaron Myers

Open Access Theses

German cockroaches are important urban pests that have been linked to asthma and serious allergic reactions in sensitized individuals. In this research project I, (i) identified different proteins expressed in the tergal glands of male German cockroaches, (ii) determined the expression levels of these proteins in different cockroach life stages and tissues, and (iii) investigated the role of the tergal gland alpha-amylase (BGTG-1) protein. ^ Four major tergal gland proteins were separated on denaturing polyacrylamide gels. With peptide sequencing two of these proteins were identified as alpha-amylase (BGTG-1) and Blattella germanica allergen 2 (Bla g 2). Both of these proteins …

Management Effects On The Environmental Footprint Of Swine Production, Aaron M. Jones

Open Access Theses

Livestock production in general is a very small contributor to GHG emissions. However, swine producers will continually be faced with a series of challenges to minimize the environmental impact of swine production. The main objectives of the the studies in this thesis were to evaluate the effects of reducing dietary CP with the supplementation of synthetic AA and the effects of feeding diets with or without antibiotics on manure generation and excretion of N and C. In Exp. 1, thirty-two barrows were used in a metabolism study to evaluate the effect of feeding reduced CP, amino acid (AA) supplemented diets …

Intelligent Sensor System For Selected Environmental Safety Application, Chen-Lin Song

Open Access Theses

Song, Chen-Lin. M.S., Purdue University, August 2015. Intelligent Sensor System for Selected Environmental Safety Applications. Major Professor: Suranjan Panigrahi

Pharmacokinetics Of Ketorolac Tromethamine In Horses After Intravenous, Intramuscular, And Oral Single Dose Administration, Alexandra Walsh Bianco

Open Access Theses

Bianco, Alexandra W. M.S., Purdue University, August 2015. Pharmacokinetics of ketorolac tromethamine in horses after intravenous, intramuscular and oral single dose administration. Major Professor: Sandra D. Taylor.

Investigations Into The Anti-Collagenase Efficacy Of Serum And Plasma, Emily Dakin Conway

Open Access Theses

Corneal ulcers are a commonly encountered problem in domesticated species and can cause significant pain, incur a high cost for the owner, and result in blindness or eventual enucleation. The progressive deepening of corneal ulcers is mediated by enzymatic destruction of stromal collagen (termed keratomalacia) when collagenases from endogenous and exogenous sources are active on the corneal surface. The inhibition of collagenases can therefore be crucial to mitigating the damage that breakdown of corneal stromal collagen causes. In ulcers where collagenase activity is suspected, the use of topical serum has been recommended, in both human and veterinary medicine, primarily due …

Application Of Biodynamic Imaging For Personalized Chemotherapy In Canine Lymphoma, Michelle Renee Custead

Open Access Theses

Biodynamic imaging (BDI) is a novel phenotypic cancer profiling technology which characterizes changes in cellular and subcellular motion in living tumor tissue samples following in vitro or ex vivo treatment with chemotherapeutics. The ability of BDI to predict clinical response to single-agent doxorubicin chemotherapy was tested in ten dogs with naturally-occurring non-Hodgkin’s lymphomas (NHL). Pre-treatment tumor biopsy samples were obtained from all dogs and treated with doxorubicin (10 M) ex vivo. BDI captured cellular and subcellular motility measures on all biopsy samples at baseline and at regular intervals for 9 hours following drug application. All dogs subsequently received treatment with …

Alpha Lipoic Acid: A Potential Therapeutic Option For Painful Peripheral Neuropathies, Jessica Curcio

Physician Assistant Scholarly Project Posters

• Peripheral neuropathy (PN) is a major public health concern.

• There are many etiologies for PN including injury, infection, toxicity, genetics, metabolic disease and nutritional deficiencies.

• Alpha lipoic acid (ALA), also known as thioctic acid, is a potent antioxidant and cofactor in many cellular metabolic processes.

• Oxidative damage plays a significant role in the pathogenesis of both diabetic peripheral neuropathy (DPN) and chemotherapy induced peripheral neuropathy (CIPN).

• Because of the antioxidant capability ALA has been studied for its potential benefit in preventing and treating PN

Implementing Animal Therapy Into Current Medicinal Practices, Jenna Schiefelbein

Physician Assistant Scholarly Project Posters

• The purpose of this study was to explore an unconventional intervention of medicine; specifically the integration of animals into current healthcare practices.

• The review of literature evaluated the implementation of animal therapy in medicine, both in the past and present.

• It was demonstrated that incorporating animal-assistance therapy into modern day medicine had a positive correlation with overall patient health, pain control, and disposition.

Bond V. United States: Choosing The Lesser Of Two Evils, David L. Sloss

Faculty Publications

In Bond v. United States, Carol Anne Bond used toxic chemicals in an attempt to poison her husband’s lover. The federal government prosecuted Bond for violating the Chemical Weapons Convention Implementation Act of 1998 (the “CWC Act”). Congress enacted the CWC Act to implement U.S. obligations under the Chemical Weapons Convention (CWC), a multilateral treaty signed in 1993 that is designed to address the global threat posed by chemical weapons. Bond challenged the constitutional validity of the federal statute and urged the Court to overrule Missouri v Holland, a 1920 case holding that the combination of the Treaty Power and …

Avoiding Extinction, Preserving Culture: Sustainable, Sovereignty-Centered Tribal Citizenship Requirements, Michael D. Oeser

North Dakota Law Review

No abstract provided.

Rituals Upon Celluloid: The Need For Crime And Punishment In Contemporary Film, J C. Oleson

Cleveland State Law Review

Most members of the public lack first-hand experience with the criminal justice system; nevertheless, they believe that they possess phenomenological knowledge about it. In large part, the public’s understandings of crime and punishment are derived from television and film, which provide modern audiences with a vision of institutions that are normally occluded from view. While public rituals of punishment used to take place on the scaffold, equivalent moral narratives about crime and punishment now occur on film because modern punishment is imposed outside of the public gaze. Yet because crime films distort what they depict, the public’s view of crime …

"The Millennials Are Coming!" : Improving Self-Efficacy In Law Students Through Universal Design In Learning, Jason S. Palmer

Cleveland State Law Review

The Millennial generation has arrived in law school. This new generation of self-confident and extremely high achieving learners merits a new interdisciplinary approach to legal education. Some institutions have explored formative assessments and regulated self-learning to improve academic success. Other universities have looked to universal design, specifically universal design in learning or universal design in instruction, as a mechanism for furthering educational goals for their students. All agree that a lack of self-efficacy can prevent Millennial students from overcoming challenges in their educational growth, and that high self efficacy, the ability to put forth effort and persistence to successfully accomplish …

The War With The Sioux, Karl Jakob Skarstein

Digital Press Books

Translated Melissa Gjellstad and Danielle Skjelver With contributions from Dakota Goodhouse and Richard Rothaus

The Dakota War (1862-1864) ranks among the most overlooked conflicts in American History. Contemporary with the American Civil War, the Dakota War featured significant fighting, tactical brilliance, and strategic savvy set in the open landscape of the Northern Plains in Minnesota and North Dakota.

Karl Jakob Starstein’s The War with the Sioux tells the story of the Norwegian immigrants, American soldiers, and Lakota and Dakota Indians as they sought to protect their ways of life. Translated from Norwegian and supplemented with new introductions by Melissa Gjellstad, …

Transcriptional Stress Response In Foodborne Pathogens, Aaron M. Pleitner

Open Access Dissertations

Novel molecular method use is leading to better identification and understanding of microbial presence in food and food processing environments. The application of molecular methods targeting foodborne pathogens provides genetic profiling and targeted intervention methods. Whole-genome sequencing (WGS) provides information on the genomic uniqueness of specific pathogens and is being implemented in epidemiological investigations. Transcriptomic profiling allows for tracking the differential expression of genes and elucidating stress responses. Effective methods and treatments require an understanding of intervention (e.g. sanitizers) and treatment (e.g. antibiotics) mechanisms and efficacies. Accurate novel molecular method use requires proper learning of theory and data management. ^ …

Synthetic Steganography: Methods For Generating And Detecting Covert Channels In Generated Media, Philip Carson Ritchey

Open Access Dissertations

Issues of privacy in communication are becoming increasingly important. For many people and businesses, the use of strong cryptographic protocols is sufficient to protect their communications. However, the overt use of strong cryptography may be prohibited or individual entities may be prohibited from communicating directly. In these cases, a secure alternative to the overt use of strong cryptography is required. One promising alternative is to hide the use of cryptography by transforming ciphertext into innocuous-seeming messages to be transmitted in the clear. ^ In this dissertation, we consider the problem of synthetic steganography: generating and detecting covert channels in generated …

Show Horse Welfare, Melissa A. Voigt

Open Access Dissertations

In recent years there has been an increase in the public's attention to situations where trainers, owners, and handlers have compromised the well-being of show horses for the sake of winning. These situations may be due to training negligence or naivety of individuals working with the horse. Either way, due to these incidents, increasing pressure has been placed on the horse industry to address show horse welfare. The purpose of this research was to expound on the welfare of stock-type show horses through the perspective of those directly involved; considering the understanding of welfare, the value placed on welfare, and …

Overweight Vehicle Permitting Alternatives, Stephanie R Everett

Open Access Dissertations

Overweight vehicles exceed the federal and/or state statutory limits for either the gross vehicle weight (GVW) or the weight of individual axles or axle groups. National and state limits on vehicle weights were established to preserve the highway infrastructure. Past research has shown that overweight operations, while causing significant damage to roads and bridges, can enhance the trucking industry productivity, and thus yield economic benefits both regionally and nationally. In the United States, individual states administer oversize and overweight vehicle permit programs to regulate and collect revenues from overweight operations. Differences in the truck size and weight limits and overweight …

The Epidemiology Of Coxiella Burnetii In Goats In Indiana, Amy E. Bauer

Open Access Dissertations

Coxiella burnetii is an obligate, intracellular bacterium and the etiologic agent of the zoonotic disease Q fever. Through the presence of an environmentally resilient small cell variant, C. burnetii can persist outside of a host in the face of extremes in temperature, humidity, and pressure. C. burnetii is considered to be ubiquitous in the environment and endemic in cattle, sheep and goat populations. These same species are the main reservoirs for human infection with C. burnetii. The overall goal of this project was to develop a baseline understanding of the epidemiology of C. burnetii in goats in Indiana. Specific areas …

Design Of An Embedded Fluorescence Imaging System For Implantable Optical Neural Recording, Giovanni Barbera

Open Access Dissertations

The brain is the most complex and least understood biological system known to man. New imaging techniques are providing scientists with an entirely new perspec- tive on the study of the functional brain at a neural circuit level, enabling in-depth understanding of both physiological processes and animal models of neurological and psychiatric diseases which currently lack e↵ective treatments. These new tools come at the cost of meeting the challenges associated with the miniaturization of the hard- ware for in vivo recordings

Control Of Bovine Pyruvate Carboxylase Expression By Saturated And Unsaturated Fatty Acids And Impact On Fatty Acid Metabolism, Katherine Elizabeth Boesche

Open Access Dissertations

Pyruvate carboxylase (PC; EC 6.4.1.1) ostensibly links carbohydrate and lipid metabolism by supplying oxaloacetate (OAA) from the carboxylation of pyruvate. The OAA pool is necessary in maintaining the anaplerotic supply of carbons to the TCA cycle, and to promote the complete oxidation, to CO2, of acetyl-CoA. The actions of PC in supplying OAA are critical during periods of increased cellular lipid load, including the negative energy balance experienced by periparturient dairy cows. The bovine PC gene contains three promoter sequences, with products of the proximal promoter (PCP1) being specific to glucogenic and lipogenic tissues. Previous work links control of bovine …

Impact Of L-Arginine Transportation On Myeloid-Derived Suppressor Cell Function, Cansu Cimen Bozkus

Open Access Dissertations

Inflammatory chronic prostatitis/chronic pelvic pain syndrome has been linked to autoimmune inflammation. Likewise, prostatitis has been linked to prostate cancer development and progression. A better understanding of the mechanisms by which inflammation is regulated may provide the foundation for novel approaches to controlling inflammation. Myeloid-derived suppressor cells (MDSC) are a heterogeneous population of immature cells that expand during benign and cancer-associated inflammation. MDSC are characterized by their ability to potently inhibit T cell responses. Therefore, by dampening inflammation, MDSC benefit autoimmune diseases. Instead, they aggravate cancer by blocking antitumor immune responses. Identification of mechanisms underlying MDSC activities can enable the …

Examining The Use Of User-Centered Design In Gamification: A Delphi Study, Yang Chen

Open Access Dissertations

This study examined using the user-centered design (UCD) approach in gamification product development with the research question, "What opinions do experienced gamification designers have in using the UCD method as they develop and design gamification products?" Through the multi- phase interactions between researcher and participants of this Delphi study, specific survey questions were developed such as, how does the UCD method work in gamification design, how well does it work, and suggestions on how it should be used. Gamification design experts were recruited as research participants and four Delphi rounds of data collection were conducted. Thirtythree design heuristics within five …

Assessing Inter-Rater Agreement For Compositional Data, Ningning Chen

Open Access Dissertations

Compositional data are non-negative vectors whose elements sum to one (e.g., [0.1, 0.5, 0.4]). This type of data occurs in many research areas where the relative magnitudes between the vector’s elements are of primary interest. In this dissertation we propose novel methodology for assessing inter-rate agreement based on compositional data. This is needed because existing agreement measures either involve converting the vector to a univariate value, thereby losing information, or they fail to account for the sum-to-one restriction. We propose a novel Bayesian approach, enabled by Markov chain Monte Carlo, to investigate differences in the pattern of compositional vector scores. …