Digital Commons Network^™

Cross-Linked Alginate Film Pore Size Determination Using Atomic Force Microscopy And Validation Using Diffusivity Determinations, Cheryl Simpliciano, Larissa Clark, Behrokh Asi, Nathan Chu, Maria Mercado, Steven Diaz, Michel Goedert, Maryam Mobed-Miremadi

Bioengineering

The deficit of organ donors has fueled the need for advances in tissue engineering and regenerative medicine. Microencapsulation in alginate immuno-isolation membranes has been used to treat many disabling metabolic disorders, namely, phenylketonuria, kidney failure and diabetes mellitus. Systematic nutrient flux determinations are hindered by the lack of experimental data on alginate-based membrane topography and the pore size thus preventing the full therapeutic potential of the bio-membranes to be reached. In this study, samples of cross-linked alginate membranes were subjected to the following analytical characterization: 1) pore size characterization using atomic force microscopy operated in contact mode to detect and …

Com Outlook Fall 2013, College Of Osteopathic Medicine

COM Outlook

No abstract provided.

2012-2013 Hccp Year-End Summary, Kristen S. Cloutier

Year-end Summaries

No abstract provided.

Law & Health Care Newsletter, V. 21, No. 1, Fall 2013

Law & Health Care Newsletter

No abstract provided.

Scholarworks Statistics - October 2013, Scholarworks

ScholarWorks Reports

For the month of October 2013, ScholarWorks recorded a total 28,413 full-text downloads and 17,360 page views.

The Pillar - Fall 2013, College Of Education And Human Development

College of Education and Human Development News

No abstract provided.

Center For Grassland Studies, Fall 2013, Volume 19, No. 3

Center for Grassland Studies: Newsletters

Insects as Agents of Improved Rangeland Quality and Cattle Production

From the Director

Another Successful Nebraska Grazing Conference

Sand County Foundation Conservation Partners Hold National Symposium

Nominate Someone for Leopold Conservation Award

Terry Klopfenstein Recognized as BEEF Top 50

Golf Student Breaks Guinness World Record!

CGS Associates

UNL Launches Online Grassland Management Graduate Certificate Program

Pathoscope: Species Identification And Strain Attribution With Unassembled Sequencing Data., Owen E Francis, Matthew Bendall, Solaiappan Manimaran, Changjin Hong, Nathan L Clement, Eduardo Castro-Nallar, Quinn Snell, G Bruce Schaalje, Mark J Clement, Keith A Crandall, W Evan Johnson

Computational Biology Institute

Emerging next-generation sequencing technologies have revolutionized the collection of genomic data for applications in bioforensics, biosurveillance, and for use in clinical settings. However, to make the most of these new data, new methodology needs to be developed that can accommodate large volumes of genetic data in a computationally efficient manner. We present a statistical framework to analyze raw next-generation sequence reads from purified or mixed environmental or targeted infected tissue samples for rapid species identification and strain attribution against a robust database of known biological agents. Our method, Pathoscope, capitalizes on a Bayesian statistical framework that accommodates information on sequence …

Vbp15, A Novel Anti-Inflammatory And Membrane-Stabilizer, Improves Muscular Dystrophy Without Side Effects, Christopher R. Heier, Jesse M. Damsker, Qing Yu, Blythe C. Dillingham, Tony Huynh, Heather A. Gordish-Dressman, Jyoti K. Jaiswal, Eric P. Hoffman, Kanneboyina Nagaraju, +15 Additional Authors

Genomics and Precision Medicine Faculty Publications

Absence of dystrophin makes skeletal muscle more susceptible to injury, resulting in breaches of the plasma membrane and chronic inflammation in Duchenne muscular dystrophy (DMD). Current management by glucocorticoids has unclear molecular benefits and harsh side effects. It is uncertain whether therapies that avoid hormonal stunting of growth and development, and/or immunosuppression, would be more or less beneficial. Here, we discover an oral drug with mechanisms that provide efficacy through anti-inflammatory signaling and membrane-stabilizing pathways, independent of hormonal or immunosuppressive effects. We find VBP15 protects and promotes efficient repair of skeletal muscle cells upon laser injury, in opposition to prednisolone. …

How The Trans Pacific Partnership Agreement Could Undermine Pharmac And Threaten Access To Affordable Medicines And Health Equity In New Zealand, Deborah Gleeson, Ruth Lopert, Papaarangi Reid

Health Policy and Management Faculty Publications

New Zealand's Pharmaceutical Management Agency (PHARMAC) has been highly successful in facilitating affordable access to medicines through a combination of aggressive price negotiations, innovative procurement mechanisms, and careful evaluation of value for money. Recently the US government, through the establishment of a series of bilateral and plurilateral “free” trade agreements, has attempted to constrain the pharmaceutical access programs of other countries in order to promote the interests of the pharmaceutical industry. The Trans Pacific Partnership Agreement (TPPA) represents the latest example; through the TPPA the US is seeking to eliminate therapeutic reference pricing, introduce appeals processes for pharmaceutical companies to …

Faculty Achievements, October 2013, Otterbein University

Faculty Achievement Reports

No abstract provided.

Hilary Putnam's Consistency Objection Against Wittgenstein's Conventionalism In Mathematics, Pieranna Garavaso

Philosophy Publications

Hilary Putnam first published the consistency objection against Ludwig Wittgenstein’s account of mathematics in 1979. In 1983, Putnam and Benacerraf raised this objection against all conventionalist accounts of mathematics. I discuss the 1979 version and the scenario argument, which supports the key premise of the objection. The wide applicability of this objection is not apparent; I thus raise it against an imaginary axiomatic theory T similar to Peano arithmetic in all relevant aspects. I argue that a conventionalist can explain the consistency of T and suggest that an analogous explanation can be provided for the consistency of Peano arithmetic.

Illinois Critical Access Hospitals: Managing Healthy Communities In Rural Illinois, Melissa Henriksen, Norman Walzer

Reports, Whitepapers, Articles, and Other Publications

The Illinois Critical Access Hospital Network (ICAHN), working with the Center for Governmental Studies (CGS) at Northern Illinois University recently released, “Illinois Critical Access Hospitals: Managing Healthy Communities in Rural Illinois,” the third in a series of white papers focused on rural health care issues. The ICAHN and CGS worked with hospital administrators across rural Illinois to examine PHM challenges, alternative revenue models, and promising practices that can help small hospitals respond to the new health care environment. The report identifies population health management approaches currently underway in Illinois critical access hospitals (CAHs) and other health care organizations. It also …

Life History Comparison Of Two Green Lacewing Species Chrysoperla Johnsoni And Chrysoperla Carnea (Neuroptera: Chrysopidae), Kaushalya G. Amarasekare, Peter W. Shearer

Agricultural and Environmental Sciences Faculty Research

We investigated the life histories of two green lacewing species, Chrysoperla johnsoni Henry, Wells, and Pupedis from western North America, and Chrysoperla carnea (Stephens) (Neuroptera: Chrysopidae) from western Europe in the laboratory. There were both similarities and differences in their life history characteristics. C. johnsoni exhibited a significantly longer developmental time for egg, first instar, and pupal stage than C. carnea. C. carnea exhibited a significantly shorter egg to adult developmental time than C. johnsoni. Except for the pupal stage, the survival of all other life history stages was not species-specific. All C. carnea pupae were able to develop …

Year In Review 2012-2013, Bridgewater College

Bridgewater Magazine

No abstract provided.

Improving Reuse In Software Development For The Life Sciences, Nicholas Vincent Iannotti

Open Access Dissertations

The last several years have seen unprecedented advancements in the application of technology to the life sciences, particularly in the area of data generation. Novel scientific insights are now often driven primarily by software development supporting new multidisciplinary and increasingly multifaceted data analysis. However, despite the availability of tools such as best practice frameworks, the current rate of software development is not able to keep up with the needs of scientists. This bottleneck in software development is largely due to code reuse generally not being applied in practice.

This dissertation presents Legwork, a class library of reuse-optimized design pattern implementations …

Road Cuts And Atterberg Limits Of Little Creek Road, Christopher A. Marquis

Natural Resources Management and Environmental Sciences

This senior project examined road cuts and soil adjacent to the road cut, along Little Creek road. Contrasting a landslide hillslope complex to a hillslope drainage complex, the project also compared the organic soil horizon to the mineral soil horizon in both soil units. The soils were analyzed using qualitative and quantitative measures of soil properties. The project utilized a road cut inventory to note the characteristics of the road cut such as presence of rill erosion, rock outcrop and sloping degree of the road cut. The project derived the plasticity index for both organic and mineral horizons, and compared …

Project-Oriented Science Instruction Involving General-Education Undergraduates Serving As Mentors To Underprivileged Middle-Students Students, Walter S. Borowski, Malcolm P. Frisbie, Tara Shepperson, Linda Frost

EKU Faculty and Staff Scholarship

We report results from a novel, project-based science course funded by the NSF for general-education students in the EKU Honors Program and for middle school students. Key aspects of the course are: (1) instruction in the natural sciences adopting a regional context; (2) investigation of the water quality of a local stream involving all portions of a scientific study from planning to data collection and analysis to presentation; and (3) direct mentoring of underprivileged, seventh-grade students by honors students in project activities, including trips to campus for laboratory work and presentations. The course is meant to provide high-quality scientific instruction …

Wellesley Magazine Fall 2013, Wellesley College Alumnae Association

Wellesley Magazine (Alumnae Association)

Featured in this issue:

Getting to 'I Do' / by Jennifer Vanasco ’94

Campus Wags / by Alice Hummer, Jennifer Flint, and Lisa Scanlon ’00

Living Faith / by Jana Riess ’91

Strategies Of Cooperation And Punishment Among Students And Clerical Workers, Maria Bigoni, Gabriele Camera, Marco Casari

Economics Faculty Articles and Research

We study the individual behavior of students and workers in an experiment where they repeatedly face the same cooperative task. The data show that clerical workers differ from college students in overall cooperation rates, strategy adoption and use of punishment opportunities. Students cooperate more than workers. Cooperation increases in both subject pools when a personal punishment option is available. Students are less likely than workers to adopt strategies of unconditional defection, and more likely to select strategies of conditional cooperation. Finally, students are more likely than workers to sanction uncooperative behavior by adopting decentralized punishment, and also personal punishment when …

Second Messenger/Signal Transduction Pathways In Major Mood Disorders: Moving From Membrane To Mechanism Of Action, Part Ii: Bipolar Disorder, Mark Niciu, Dawn F. Ionescu, Daniel C. Matthews, Erica M. Richards, Carlos A. Zarate

Psychiatry and Behavioral Sciences Faculty Publications

The etiopathogenesis and treatment of major mood disorders have historically focused on modulation of monoaminergic (serotonin, norepinephrine, dopamine) and amino acid [γ-aminobutyric acid (GABA), glutamate] receptors at the plasma membrane. Although the activation and inhibition of these receptors acutely alter local neurotransmitter levels, their neuropsychiatric effects are not immediately observed. This time lag implicates intracellular neuroplasticity as primary in the mechanism of action of antidepressants and mood stabilizers. The modulation of intracellular second messenger/signal transduction cascades affects neurotrophic pathways that are both necessary and sufficient for monoaminergic and amino acid–based treatments. In this review, we will discuss the evidence in …

Medicine + Health, Fall 2013, George Washington University, School Of Medicine And Health Sciences, Office Of Communications And Marketing

Medicine + Health Magazine

No abstract provided.

Engineering News, Fall 2013, School Of Engineering

Engineering News

No abstract provided.

Fall 2013, Seattle University

Seattle University Magazine

No abstract provided.

External Influence As An Indicator Of Scholarly Importance, Ho Fai Chan, Bruno S. Frey, Jana Gallus, Markus Schaffner, Benno Torgler, Stephen Whyte

Fondazione Eni Enrico Mattei Working Papers

The external influence of scholarly activity has to date been measured primarily in terms of publications and citations, metrics that also dominate the promotion and grant processes. Yet the array of scholarly activities visible to the outside world are far more extensive and recently developed technologies allow broader and more accurate measurement of their influence on the wider societal discourse. Accordingly we analyze the relation between the internal and external influences of 723 top economics scholars using the number of pages indexed by Google and Bing as a measure of their external influence. Although the correlation between internal and external …

Spiritual Dangers, Matthew Ferrence

CutBank

No abstract provided.

Educational Leadership Newsletter Fall 2013, Educational Leadership Department, University Of Southern Maine

Educational Leadership Newsletters

Inside this issue:

• News from the Chair
• USM Pioneer Program: STEM Scholarships
• Faculty Highlights: Anita Stewart McCafferty
• Spring 2014 Registration

Macalester Today Fall 2013, Macalester College

Macalester Today

No abstract provided.

Bucknell River Reporter, Bucknell University Environmental Center

Newsletters

Volume 1, issue 3 of the Bucknell River Reporter edited by Fred Swader. Articles include -- The River: no news = good news (?), An engineer’s perspective of our local streams and rivers, How Susquehanna river towns deal with flooding, A Fragmented System: Dams in the Susquehanna Watershed, Science, “safety,” and the State of the River, Exploring the river, Watching the river flow, Susquehanna River Initiative.

Growing A Healthy Future, Fall 2013

Institute of Agriculture and Natural Resources: Institute Publications

What's new at IANR; Who's new at IANR; Globe-trotting beans; Science in the know; Gilt puberty; Soybean agreement; Firing down wildfires; Energy interest; The vet is in; By the Numbers