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The Scientific Evidence Validating The Use Of Honey As A Medicinal Agent, Raitzel Chemda Bernstein

The Science Journal of the Lander College of Arts and Sciences

Honey has been used to treat wounds, infections, and other diseases since ancient times. Due to the widespread bacterial resistance to antibiotics, scientists have investigated the healing power of honey. Numerous studies have documented the broad-spectrum antibacterial effect of honey and its success in inhibiting MRSA. The use of honey as a wound dressing has proven to successfully heal chronic wounds in short amounts of time by inhibiting pathogens, reducing inflammation, rebuilding damaged tissue, and minimizing scarring. The mechanisms of action are directly related to the high hydrogen peroxide and rich polyphenol content present in honey. These two components account …

Cancer Immunotherapy Treatments, Shifra Sadowsky

The Science Journal of the Lander College of Arts and Sciences

Cancer is the second leading cause of death in American, with over half a million deaths from cancer reported in 2009. Cancer chemotherapy treatments were developed in the nineteen hundreds and remain the backbone of current treatments; however, they have some limitations. New immunotherapy cancer treatments, where biologic agents are given to patients to influence the body’s natural immune response, are being researched. Among these immunotherapy treatments are co-inhibition blockade of T cells, and combination blockade treatments together with chemotherapy treatment. This review will discuss T cell activation and the role of T cell coinhibitors such as CTLA-4 and PD-1 …

Alopecia Areata: An Overview, Chaya Gestetner

The Science Journal of the Lander College of Arts and Sciences

This review seeks to find the most efficient treatment for alopecia areata. Alopecia is not very well understood as demonstrated by the unsatisfactory treatment options. The author reviewed many studies with different treatment options and concluded that treatment with Diphenylcyclopropenone (DPCP), a topical sensitizer, has the best results and that extensive research into the pathogenesis of alopecia areata is still necessary and may result in better treatment options for those afflicted with the disease.

The Pathogenesis And Treatment Of Gout, Daniel Silberstein

The Science Journal of the Lander College of Arts and Sciences

In the past, the etiology of gout was simplistically believed to be based in the generous indulgence of rich foods and alcohol. However, research has revealed that gout has complex environmental and genetic origins. Specifically, researchers have begun to focus attention on the molecular basis of gout and its related features. These features include hyperuricemia, the stages of gout, and the decreased solubility of uric acid. Furthermore, with epidemiologic evidence indicating that the prevalence of gout is consistently rising, it is imperative that medical providers understand the research-based guidelines for treatment. This includes what medications to administer, monitoring for drug-induced …

Huntington's Disease And Its Effect On The Brain, Shaina Rivkin-Drizin

The Science Journal of the Lander College of Arts and Sciences

Huntington's disease is a neurodegenerative disease that leads to gradual extensive brain damage, especially in the striatum and the cerebral cortex. Initial symptoms are cognitive difficulties, loss of motor contra and sudden mood imbalances. Cognitive function slowly declines into dementia, coupled with behavioral and psychiatric problems. Sufferers die within 20 years due to illness complications: a fall, pneumonia, or heart disease (Walker, 2007). This paper reviews the principle biological cause of the disease, its effect on the brain, diagnosis, and treatment.

Microparticle Function, Leorra Kohen

The Science Journal of the Lander College of Arts and Sciences

Microparticles are emerging as an integral part of the vascular system. The microparticles are derived from stimulated or apoptotic endothelial cells, platelets, and leukocytes. They are involved in coagulation and regular cell function. Excessive numbers of microparticles contribute to artherosclerosis, chronic renal failure, and metabolic syndrome. Microparticle levels may be reduced by medications, relieving symptoms for awhile. Studies are being done to predict disease by counting microparticles. Further research must be done to understand and make use of microparticles.

Full Issue: Volume 7, Number 1

The Science Journal of the Lander College of Arts and Sciences

No abstract provided.

The Rollamo 2013, Missouri University Of Science And Technology

Yearbooks

No abstract provided.

An Exploration Of Compulsory Licensing As An Effective Policy Tool For Antiretroviral Drugs In India, Dipika Jain, Jonathan J. Darrow

Health Matrix: The Journal of Law-Medicine

No abstract provided.

Selection And Clustering For Disease Associated Genetic Variants, Yubo Zou

Theses and Dissertations

Epigenetics is the study of chemical reactions, which are orchestrated for the development and maintenance of an organism. Genetic or epigenetic variants (GEVs) encompass different types of genetic measures, such as Deoxyribonucleic acid (DNA) methylation at different CpG sites, expression level of genes, or single nucleotide polymorphisms (SNPs). With the development of technology, huge amount of genetic and epigenetic information is produced. However, the rich information potentially brings in challenges in data analyses. Thus it is necessary to reduce the dimension of data to improve efficiency. In my dissertation, I will focus on two directions of dimension reduction: variable selection …

Computational Analysis And Prediction Of Genome-Wide Protein Targeting Signals And Localization, Jhih-Rong Lin

Theses and Dissertations

Computational prediction of protein subcellular localization can greatly help to elucidate its functions. Despite the existence of dozens of protein localization prediction algorithms, the prediction accuracy and coverage are still low. Several ensemble algorithms have been proposed to improve the prediction performance, which usually include as many as 10 or more individual localization algorithms. However, their performance is still limited by the running complexity and redundancy among individual prediction algorithms. In the first part of the dissertation, we propose a novel method for rational design of minimalist ensemble algorithms for practical genome-wide protein subcellular localization prediction. The algorithm is based …

Description And Service Innovation In Adolescent Transition Within Kentucky State Agency Education Programs, Amy C. Marshall

Theses and Dissertations--Rehabilitation Sciences

Of all Kentucky youth, state agency children are at the highest risk of making unsuccessful post-secondary transitions to adulthood. The intent of both studies comprising this dissertation was to understand and guide transition planning to make future improvements to transitions of adolescents in state agency programs.

The Kentucky Youth at Risk in Transition Study was a mixed methods study that identified and described the understandings of student transitions in state agency education programs from the perspectives of youth and administrators. The study included 105 nontraditional education programs funded and supervised by the Kentucky Educational Collaborative for State Agency Children (KECSAC). …

Evading Innate And Adaptive Immunity During Adenovirus Cell Entry, Shauna Marvin

Dissertations

Adenovirus (Ad), a non-enveloped, dsDNA virus, enters cells via clathrin-mediated endocytosis. For viral genome delivery to the nucleus, Ad must penetrate endosomal membranes to create defects sufficient for the passage of the 90 nm diameter capsid across cell membranes. Recent observations suggest that adenovirus type 5 (Ad5) capsid uncoating occurs at the cell surface upon binding to both the coxsackievirus and adenovirus receptor and α_v integrins. This uncoating event leads to the exposure of the capsid membrane lytic protein VI. Using the cytosolic protein galectin-3 (gal3) as a marker of membrane rupture, we demonstrate that Ad5 membrane rupture occurs …

Reclaiming Hazelwood: Public School Classrooms And A Return To The Supreme Court's Vision For Viewpoint-Specific Speech Regulation Policy, Brad Dickens

Richmond Public Interest Law Review

Federal and circuit courts continue to fiercely debate whether the Supreme Court's 1988 ruling in Hazelwood v. Kuhineier requires school policies regulating student speech and expression to be viewpoint neutral. However, this note suggests that the language of Hazelwood itself shows that the Circuit debate may be misguided. The Supreme Court intended Hazelwood to stand as a narrow exception to its earlier holding in Tinker, and Hazelwood only applies in instances where the government's own voice is implicated, largely in a public context. When the school, and in effect the government, is speaking with its own voice, the school must …

International Health Emergencies In Failed And Failing States, Chiara Giorgetti

Law Faculty Publications

Global health emergencies, particularly those occurring in Jailed and Jailing States, can become threats to the stability of the international community. This Article assesses the international mechanisms available to respond to such emergencies. After defining global health emergencies, it discusses the implications of global outbreaks in Jailed and Jailing States. It then examines the role played by the World Health Organization in controlling global health emergencies, with particular reference to the newly amended 2005 International Health Regulations and the Global Outbreak Alert and Response Network. Finally, it explores the role of other international organizations, including the United Nations Children's Fund …

Innovative Food Product Development Using Molecular Gastronomy: A Focus On Flavour And Sensory Evaluation, Mark Traynor

Doctoral

The primary goal of this research was to develop novel ice cream products using the principles of molecular gastronomy. An ice cream model system (emulsion) was developed, in which the effects of ingredient levels on stability and formation were investigated and optimised using Response Surface Methodology (RSM). Two characteristic volatiles of banana (isoamyl acetate and furfuryl acetate) were added to the optimised emulsion, and their headspace emission was quantified using Solid Phase Microextraction with Gas Chromatography Mass Spectrometry. RSM was used to investigate the main and interactive effects of ingredient, salt and pH levels on the headspace emission of these …

'Simple' Takes On The Supreme Court, Robert Tsai

Scholarly Articles in Law Reviews & Journals

This essay assesses black literature as a medium for working out popular understandings of America’s Constitution and laws. Starting in the 1940s, Langston Hughes’s fictional character, Jesse B. Semple, began appearing in the prominent black newspaper, the Chicago Defender. The figure affectionately known as “Simple” was undereducated, unsophisticated, and plain spoken - certainly to a fault according to prevailing standards of civility, race relations, and professional attainment. Butthese very traits, along with a gritty experience under Jim Crow, made him not only a sympathetic figure but also an armchair legal theorist. In a series of barroom conversations, Simple ably critiqued …

Predictors Of Resilience Among Hispanic Adults: Stepwise Analyses From Late Adolescence To Adulthood, Katherine Marie Aguirre

Open Access Theses & Dissertations

Background: The focus of this study was factors that affect resilience as a health outcome among Hispanic adults. Some Hispanics and other members of disadvantaged and vulnerable populations have developed remarkable ways of coping with adversity, such as positive reframing (Farley, Galves, Dickinson, & Perez, 2005). Purpose: This research aimed to examine various ways of coping in response to difficult life situations for Hispanic adults and identify those that are associated with resilient outcomes. Methods: The present sub-study focused on difficult life problem narratives from the semi-structured interviews conducted in Dr. Felipe González Castro's Corazón projects (Castro, Kellison, Boyd & …

Determination Of The Effects Of Zno And Ceo2 Nanoparticles In Mesquite (Prosopis Juliflora) And Soybean (Glycine Max): Synchrotron And Spectroscopic Approaches, Jose Angel Hernandez Viezcas

Open Access Theses & Dissertations

The rapid growth of nanotechnology is exposing the environment to abnormal concentrations of engineered nanoparticles (NPs). There is concern about the unknown consequences of NPs on the environment and human health. This Dissertation has relied significantly on Synchrotron and other spectroscopic techniques to give insights on the effects, speciation and distribution of two metal oxide nanoparticles (ZnO, CeO2) on two plant species (Mesquite and Soybean). We evaluated the effects of ZnO (10 nm) and CeO2 (8 nm) NPs on a plant species native to the semi-arid regions of North America, Mesquite (Prosopis juliflora velutina). Mesquite plants grown in hydroponic culture …

Arab Muslim Immigrant Women's Experiences Of Living In The United States: A Qualitative Descriptive Study, Maissa Khatib

Open Access Theses & Dissertations

Background: Over three million Arab Muslims live in the United States, and more than half are women (Nasser-McMillan, 2003). Little is known about these women in the growing and diverse Arab American Muslim population, and there is limited information available regarding their experiences of living in the U.S. Their experiences influence multiple aspects of their lives, including functioning in mainstream culture, use of resources or agencies, and the decisions they make that shape their acculturation outcome.

Purpose: To describe the experiences of Arab Muslim immigrant women living in the U.S.

Methods: This qualitative study examined the shared experiences of immigrant …

The Impact Of Interpersonal Communication On Breastfeeding, Jennifer Alarcon

Open Access Theses & Dissertations

The medical community has offered a lot of evidence in support of breastfeeding which has led to many of the leading medical associations (i.e. the American Academy of Pediatrics, World Health Organization) to recommend breastfeeding infants exclusively for the first six months of life and for at least a full year, up to two years or whatever is mutually desirable to mother and child. However, in the United States, many mothers do not follow this recommendation. Research shows that instances of women being unable to breastfeed exist but are minimal. Many people have attempted to address the problem of low …

The Impact Of Fear Of Falling On Functional Independence, Katherine Aileen Lawson

Open Access Theses & Dissertations

ABSTRACT

Falls are the fifth leading cause of death for persons over the age of 55 (CDC, 2010). However, not all falls result in death. In 2006, 10.5% or 2.1 million visits to the emergency room were the result of older adults falling. Non-fatal falls have long-term effects that impact a person's well-being physically, financially, and emotionally. It is estimated that health care costs of non-fatal falls is expected to reach $54.9 billion by 2020 (Englander, Hodson & Terregrossa, 1996). Intrinsic and extrinsic fall risk factors have been identified for persons over the age of 65. Intrinsic fall risk factors …

The Strength Of Family Bonds: A Look Into The Lives Of A Family That Has Overcome Adversity And Marginality, Angelique Nevarez Maes

Open Access Theses & Dissertations

In the recent literature that entails the effectiveness of parent/child bonds in deterring children from crime and related deviant activities, little information is mentioned about the effectiveness of Kinship (extended family members) and its possible effectiveness in deterring an individual from crime and related deviant activities. Adverse events such as drug abuse, early death, prostitution and gang activity can plague a family and threaten its unity when parental bonds are absent or non-consistent during adolescence. Marginalities such as poverty and racism take the family unit to the edge of society only serve to further the extent of the damage that …

Theoretical Communities Of Praxis: The University Writing Center A Cultural Contact Zone, Randall William Monty

Open Access Theses & Dissertations

The fundamental purpose of Theoretical Communities of Praxis: The University Writing Center as Cultural Contact Zone is to investigate the situatedness of Writing Center Studies, defining it as an autonomous (sub)discipline and interdisciplinary contact zone within the larger discipline of Rhetoric and Composition. In order to meet this objective, a "Communities of Praxis" methodological and theoretical framework, based on scholarship of Critical Discourse Analysis, ecocomposition, and Contextualist Research Paradigm, is applied in the analysis of a variety of WCS discourses. In doing so, WCS is repositioned as a series of interrelated, triangulated contact zones that are based on collaborative interactions …

Tea Party Movement Mobilization: Examining The Role Of Emotive Cues And Strategic Appeals, Rebeca Beatriz Puentes

Open Access Theses & Dissertations

Campaign messages used by political parties have given scholars a rich opportunity to analyze the impact that such cues may have on voters. While voter mobilization and participation is a necessity for a democracy's survival, certain messages used by very conservative movements and conservative parties may encourage intolerance towards minorities. This study examines the racial cues and appeals used by the Tea Party movement in the United States and the influence that such emotionally-charged appeals have on citizen support for very conservative political parties, movements, and policies. As my main theoretical framework, I merge political opportunity theory and intergroup emotions …

The Chicana Experience In Indonesia: An Autoethnography And Dialogic Performance Evaluating The Influence Of Cultural Identity And Gender, Bianca Ramirez

Open Access Theses & Dissertations

This study seeks to evaluate how aspects of cultural identity, gender and religion play a role on a Chicana's (mestiza's) experience of studying abroad internationally through an Indonesian conservation program. The experience of traveling to Indonesia, engaging in cross-cultural dialogue, and experiencing adversities prohibiting multiculturalism, influences the ability of the Chicana/o ethnographer to examine cross-cultural parallels in dialect and behavior. I also analyzed the rhetoric contained within the dialogic performances of the mestiza ethnographer's documented experiences. Lastly, the intersections of cultural identity, gender, and class were evaluated to determine their influence on the mestiza ethnographer's ability to successfully engage in …

Two-Photon Microscopy Of Nanoparticles And Biotissues, Judith Noemi Rivera

Open Access Theses & Dissertations

Biomedical Imaging is an important tool in medical research and clinical practice. From understanding the fundamental processes involved in our biological makeup to its use in diagnostics in helping determine what ails us, the advancements in imaging and microscopy have helped shape our view of the world and nature. Microscopy in particular is often used to study the smallest of cells and their dynamical properties while attempting to minimally change the sample being studied. My research objective is largely divided into two parts. The first part consists of designing a video-rate raster scanning two-photon microscope that is faster than current …

Treatment For Children With High Functioning Autism: A Comparison Of Social Stories To Musically Adapted Social Stories, Veronica M. Torres

Open Access Theses & Dissertations

The incorporation of music and social stories has been seldom tested, thus a study which uses a single-subject, alternating treatment design assesses the effects of standard social stories versus musically adapted social stories on the pragmatic abilities of an individual with high-functioning autism is presented. The goal of this project was to determine whether read social stories versus musically adapted social stories would be more beneficial in reducing problem behaviors in a child with high-functioning autism. Both types of social stories were implemented with the participant and the data supported the effectiveness of both treatments. Though the musically adapted social …

Structure And Electronic Properties Of Pure And Nitrogen Doped Nanocrystalline Tungsten Oxide Thin Films, Vemnkata Rama Sesha Ravi Kumar Vemuri

Open Access Theses & Dissertations

Tungsten oxide (WO₃) is a multifunctional material which has applications in electronics, sensors, optoelectronics, and energy-related technologies. Recently, electronic structure modification of WO₃ to design novel photocatalysts has garnered significant attention. However, a fundamental understanding of nitrogen induced changes in the structure, morphology, surface/interface chemistry, and electronic properties of WO₃ is a prerequisite to producing materials with the desired functionality and performance. Also, understanding the effect of thermodynamic and processing variables is highly desirable in order to derive the structure-property relationships in the W-O/W-O-N material system. The present work was, therefore, focused on studying the effects …

International Polar Year (Ipy) Back To The Future (Btf): Changes In Arctic Ecosystem Structure Over Decadal Times Scales, Sandra Villarreal

Open Access Theses & Dissertations

Arctic vegetation communities are responding to climate warming through shifts in species composition and diversity but most observations have been made over relatively short time frames, and/or in association with experimental manipulations. Because vegetation plays a key role in regulating ecosystem productivity, nutrient cycling, surface energy budgets, and trophic interactions in the Arctic, there is a need to better understand shifts in tundra vegetation communities over decadal time scales. Understanding these shifts and their impact on ecosystem structure and function in the Arctic has important implications for predicting the future state of both the Arctic and the Earth System. Long …